#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q6ZN18 uniprotkb:Q92833 intact:EBI-743256|ensembl:ENSP00000381840|uniprotkb:Q59FS5|uniprotkb:Q6ZN62|uniprotkb:Q96BG3 intact:EBI-1222720|uniprotkb:Q5U5L5|uniprotkb:A8K9Z6|uniprotkb:B7Z5S5|uniprotkb:Q86X63|uniprotkb:B7Z8L0|ensembl:ENSP00000341280 psi-mi:aebp2_human(display_long)|uniprotkb:Adipocyte enhancer-binding protein 2(gene name synonym)|uniprotkb:AEBP2(gene name)|psi-mi:AEBP2(display_short) psi-mi:jard2_human(display_long)|uniprotkb:JARID2(gene name)|psi-mi:JARID2(display_short)|uniprotkb:JMJ(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830755|imex:IM-21659-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000139154(gene)|interpro:IPR036236|ensembl:ENST00000398864(transcript)|go:"GO:0000785"(chromatin)|mint:Q6ZN18|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001107648.1|refseq:NP_694939.2|rcsb pdb:5WAI|rcsb pdb:5Y0U|rcsb pdb:5Y1U|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|reactome:R-HSA-3214841|refseq:NP_001253972.1|dip:DIP-58581N|uniprotkb:Q6ZN18(identity)|ddbj/embl/genbank:BC015624(identity)|entrezgene/locuslink:121536(identity) refseq:NP_004964.2|refseq:NP_001253969.1|refseq:XP_005249146.1|refseq:XP_016866323.1|refseq:XP_016866324.1|dip:DIP-45494N|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR036431|mint:Q92833|rcsb pdb:5HYN|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000008083(gene)|ensembl:ENST00000341776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007417"(central nervous system development)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0034721"(histone H3-K4 demethylation, trimethyl-H3-K4-specific)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|uniprotkb:Q92833(identity)|entrezgene/locuslink:3720(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:mOY+NOTaqJlXjW8v6D3YPnfnfBU9606 rogid:G/oMY7WdV7UyQwfT4MOZyET2fS89606 intact-crc:B7EEE441A248FA49|rigid:dWlnSm+wq2ppUARc8YaNokPUjiE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZN18 uniprotkb:P62891 intact:EBI-743256|ensembl:ENSP00000381840|uniprotkb:Q59FS5|uniprotkb:Q6ZN62|uniprotkb:Q96BG3 intact:EBI-8830744|uniprotkb:P02404|uniprotkb:Q9BYF2|uniprotkb:P39025|ensembl:ENSP00000355315 psi-mi:aebp2_human(display_long)|uniprotkb:Adipocyte enhancer-binding protein 2(gene name synonym)|uniprotkb:AEBP2(gene name)|psi-mi:AEBP2(display_short) psi-mi:rl39_human(display_long)|uniprotkb:RPL39(gene name)|psi-mi:RPL39(display_short)|uniprotkb:Large ribosomal subunit protein eL39(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830755|imex:IM-21659-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000139154(gene)|interpro:IPR036236|ensembl:ENST00000398864(transcript)|go:"GO:0000785"(chromatin)|mint:Q6ZN18|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001107648.1|refseq:NP_694939.2|rcsb pdb:5WAI|rcsb pdb:5Y0U|rcsb pdb:5Y1U|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|reactome:R-HSA-3214841|refseq:NP_001253972.1|dip:DIP-58581N|uniprotkb:Q6ZN18(identity)|ddbj/embl/genbank:BC015624(identity)|entrezgene/locuslink:121536(identity) refseq:NP_000991.1|rcsb pdb:4V6X|ensembl:ENSG00000198918(gene)|ensembl:ENST00000361575(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000077(Ribosomal protein L39e)|interpro:IPR020083|interpro:IPR023626|rcsb pdb:4UG0|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|uniprotkb:P62891(identity)|entrezgene/locuslink:6170(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:mOY+NOTaqJlXjW8v6D3YPnfnfBU9606 rogid:AZus2dxwJsTxAOwnJ93E2yhasbo9606 intact-crc:B7EEE441A248FA49|rigid:dWlnSm+wq2ppUARc8YaNokPUjiE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZN18 uniprotkb:P02788 intact:EBI-743256|ensembl:ENSP00000381840|uniprotkb:Q59FS5|uniprotkb:Q6ZN62|uniprotkb:Q96BG3 intact:EBI-1058602|ensembl:ENSP00000231751|uniprotkb:O00756|uniprotkb:Q16780|uniprotkb:Q16785|uniprotkb:Q16786|uniprotkb:Q16789|uniprotkb:Q8IU92|uniprotkb:Q8IZH6|uniprotkb:Q8TCD2|uniprotkb:Q96KZ4|uniprotkb:Q96KZ5|uniprotkb:Q9H1Z3|uniprotkb:Q9UCY5|uniprotkb:B7Z4X2|uniprotkb:E7EQH5|uniprotkb:B2MV13|uniprotkb:Q5DSM0|uniprotkb:A8K9U8 psi-mi:aebp2_human(display_long)|uniprotkb:Adipocyte enhancer-binding protein 2(gene name synonym)|uniprotkb:AEBP2(gene name)|psi-mi:AEBP2(display_short) psi-mi:trfl_human(display_long)|uniprotkb:LTF(gene name)|psi-mi:LTF(display_short)|uniprotkb:LF(gene name synonym)|uniprotkb:Talalactoferrin(gene name synonym)|uniprotkb:GIG12(gene name synonym)|uniprotkb:Growth-inhibiting protein 12(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830755|imex:IM-21659-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000139154(gene)|interpro:IPR036236|ensembl:ENST00000398864(transcript)|go:"GO:0000785"(chromatin)|mint:Q6ZN18|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001107648.1|refseq:NP_694939.2|rcsb pdb:5WAI|rcsb pdb:5Y0U|rcsb pdb:5Y1U|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|reactome:R-HSA-3214841|refseq:NP_001253972.1|dip:DIP-58581N|uniprotkb:Q6ZN18(identity)|ddbj/embl/genbank:BC015624(identity)|entrezgene/locuslink:121536(identity) refseq:NP_001308050.1|ensembl:ENST00000231751(transcript)|go:"GO:0001503"(ossification)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001895"(retina homeostasis)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006826"(iron ion transport)|go:"GO:0006959"(humoral immune response)|go:"GO:0008201"(heparin binding)|ensembl:ENSG00000012223(gene)|refseq:NP_001186078.1|refseq:NP_002334.2|go:"GO:0009986"(cell surface)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0030141"(secretory granule)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035580"(specific granule lumen)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1900159"(positive regulation of bone mineralization involved in bone maturation)|go:"GO:1900229"(negative regulation of single-species biofilm formation in or on host organism)|go:"GO:0042581"(specific granule)|go:"GO:1902732"(positive regulation of chondrocyte proliferation)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:2000117"(negative regulation of cysteine-type endopeptidase activity)|go:"GO:2000308"("negative regulation of tumor necrosis factor (ligand) superfamily member 11 production")|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:2001205"(negative regulation of osteoclast development)|go:"GO:0044793"(negative regulation by host of viral process)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|interpro:IPR001156(Peptidase S60, transferrin lactoferrin)|go:"GO:0045837"(negative regulation of membrane potential)|go:"GO:0048525"(negative regulation of viral process)|interpro:IPR016357(Transferrin)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051673"(membrane disruption in another organism)|interpro:IPR018195|interpro:IPR030684|mint:P02788|rcsb pdb:1B0L|rcsb pdb:1BKA|rcsb pdb:1CB6|rcsb pdb:1DSN|rcsb pdb:1EH3|rcsb pdb:1FCK|rcsb pdb:1H43|rcsb pdb:1H44|rcsb pdb:1H45|rcsb pdb:1HSE|rcsb pdb:1L5T|rcsb pdb:1LCF|rcsb pdb:1LCT|rcsb pdb:1LFG|rcsb pdb:1LFH|rcsb pdb:1LFI|rcsb pdb:1LGB|rcsb pdb:1N76|rcsb pdb:1SQY|rcsb pdb:1VFD|rcsb pdb:1VFE|rcsb pdb:1XV4|rcsb pdb:1XV7|rcsb pdb:1Z6V|rcsb pdb:1Z6W|rcsb pdb:2BJJ|rcsb pdb:2DP4|rcsb pdb:2GMC|rcsb pdb:2GMD|rcsb pdb:2HD4|rcsb pdb:2PMS|reactome:R-HSA-1222449|reactome:R-HSA-6798695|reactome:R-HSA-6799990|reactome:R-HSA-6803157|reactome:R-HSA-977225|rcsb pdb:1U62|refseq:NP_001308051.1|dip:DIP-41354N|uniprotkb:P02788(identity)|entrezgene/locuslink:4057(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:mOY+NOTaqJlXjW8v6D3YPnfnfBU9606 rogid:OLhbdYXPaD10eAg3HyhCA5Akw8o9606 intact-crc:B7EEE441A248FA49|rigid:dWlnSm+wq2ppUARc8YaNokPUjiE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZN18 uniprotkb:P47929 intact:EBI-743256|ensembl:ENSP00000381840|uniprotkb:Q59FS5|uniprotkb:Q6ZN62|uniprotkb:Q96BG3 intact:EBI-357504|ensembl:ENSP00000313571|ensembl:ENSP00000367891|ensembl:ENSP00000489395|ensembl:ENSP00000489582|uniprotkb:Q6IB87 psi-mi:aebp2_human(display_long)|uniprotkb:Adipocyte enhancer-binding protein 2(gene name synonym)|uniprotkb:AEBP2(gene name)|psi-mi:AEBP2(display_short) psi-mi:leg7_human(display_long)|uniprotkb:LGALS7(gene name)|psi-mi:LGALS7(display_short)|uniprotkb:PIG1(gene name synonym)|uniprotkb:HKL-14(gene name synonym)|uniprotkb:PI7(gene name synonym)|uniprotkb:p53-induced gene 1 protein(gene name synonym)|uniprotkb:LGALS7B(gene name)|psi-mi:LGALS7B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830755|imex:IM-21659-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000139154(gene)|interpro:IPR036236|ensembl:ENST00000398864(transcript)|go:"GO:0000785"(chromatin)|mint:Q6ZN18|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001107648.1|refseq:NP_694939.2|rcsb pdb:5WAI|rcsb pdb:5Y0U|rcsb pdb:5Y1U|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|reactome:R-HSA-3214841|refseq:NP_001253972.1|dip:DIP-58581N|uniprotkb:Q6ZN18(identity)|ddbj/embl/genbank:BC015624(identity)|entrezgene/locuslink:121536(identity) ensembl:ENSG00000178934(gene)|ensembl:ENSG00000205076(gene)|ensembl:ENSG00000282902(gene)|ensembl:ENSG00000283082(gene)|ensembl:ENST00000314980(transcript)|ensembl:ENST00000378626(transcript)|ensembl:ENST00000634448(transcript)|ensembl:ENST00000634800(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016936"(galactoside binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000562"(negative regulation of CD4-positive, alpha-beta T cell proliferation)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030640|interpro:IPR044156|mint:P47929|rcsb pdb:1BKZ|rcsb pdb:2GAL|rcsb pdb:3GAL|rcsb pdb:3ZXE|rcsb pdb:3ZXF|rcsb pdb:4GAL|rcsb pdb:4UW3|rcsb pdb:4UW4|rcsb pdb:4UW5|rcsb pdb:4UW6|rcsb pdb:4XBQ|rcsb pdb:4Y26|rcsb pdb:5GAL|rcsb pdb:5H9Q|rcsb pdb:5H9S|refseq:NP_001035972.1|refseq:NP_002298.1|uniprotkb:P47929(identity)|entrezgene/locuslink:653499(identity)|entrezgene/locuslink:3963(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:mOY+NOTaqJlXjW8v6D3YPnfnfBU9606 rogid:TIAlvVZ7rOYqTAGrYAFbJY231gc9606 intact-crc:B7EEE441A248FA49|rigid:dWlnSm+wq2ppUARc8YaNokPUjiE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZN18 uniprotkb:Q15910 intact:EBI-743256|ensembl:ENSP00000381840|uniprotkb:Q59FS5|uniprotkb:Q6ZN62|uniprotkb:Q96BG3 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 psi-mi:aebp2_human(display_long)|uniprotkb:Adipocyte enhancer-binding protein 2(gene name synonym)|uniprotkb:AEBP2(gene name)|psi-mi:AEBP2(display_short) psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830755|imex:IM-21659-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000139154(gene)|interpro:IPR036236|ensembl:ENST00000398864(transcript)|go:"GO:0000785"(chromatin)|mint:Q6ZN18|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001107648.1|refseq:NP_694939.2|rcsb pdb:5WAI|rcsb pdb:5Y0U|rcsb pdb:5Y1U|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|reactome:R-HSA-3214841|refseq:NP_001253972.1|dip:DIP-58581N|uniprotkb:Q6ZN18(identity)|ddbj/embl/genbank:BC015624(identity)|entrezgene/locuslink:121536(identity) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N|uniprotkb:Q15910(identity)|entrezgene/locuslink:2146(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:mOY+NOTaqJlXjW8v6D3YPnfnfBU9606 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 intact-crc:B7EEE441A248FA49|rigid:dWlnSm+wq2ppUARc8YaNokPUjiE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZN18 uniprotkb:P31151 intact:EBI-743256|ensembl:ENSP00000381840|uniprotkb:Q59FS5|uniprotkb:Q6ZN62|uniprotkb:Q96BG3 intact:EBI-357520|uniprotkb:Q6FGE3|uniprotkb:Q5SY67|uniprotkb:Q9H1E2|ensembl:ENSP00000357711|ensembl:ENSP00000357712 psi-mi:aebp2_human(display_long)|uniprotkb:Adipocyte enhancer-binding protein 2(gene name synonym)|uniprotkb:AEBP2(gene name)|psi-mi:AEBP2(display_short) psi-mi:s10a7_human(display_long)|uniprotkb:S100A7(gene name)|psi-mi:S100A7(display_short)|uniprotkb:PSOR1(gene name synonym)|uniprotkb:S100A7C(gene name synonym)|uniprotkb:S100 calcium-binding protein A7(gene name synonym)|uniprotkb:Psoriasin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830755|imex:IM-21659-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000139154(gene)|interpro:IPR036236|ensembl:ENST00000398864(transcript)|go:"GO:0000785"(chromatin)|mint:Q6ZN18|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001107648.1|refseq:NP_694939.2|rcsb pdb:5WAI|rcsb pdb:5Y0U|rcsb pdb:5Y1U|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|reactome:R-HSA-3214841|refseq:NP_001253972.1|dip:DIP-58581N|uniprotkb:Q6ZN18(identity)|ddbj/embl/genbank:BC015624(identity)|entrezgene/locuslink:121536(identity) ensembl:ENSG00000143556(gene)|ensembl:ENST00000368722(transcript)|ensembl:ENST00000368723(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001525"(angiogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008544"(epidermis development)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045087"(innate immune response)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051238"(sequestering of metal ion)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071624"(positive regulation of granulocyte chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028477|interpro:IPR034325|mint:P31151|rcsb pdb:1PSR|rcsb pdb:2PSR|rcsb pdb:2WND|rcsb pdb:2WOR|rcsb pdb:2WOS|rcsb pdb:3PSR|rcsb pdb:4AQJ|reactome:R-HSA-6798695|reactome:R-HSA-6799990|refseq:NP_002954.2|uniprotkb:P31151(identity)|entrezgene/locuslink:6278(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:mOY+NOTaqJlXjW8v6D3YPnfnfBU9606 rogid:/v8+XQ7rCMTYzq9k/KqjcSm/G0A9606 intact-crc:B7EEE441A248FA49|rigid:dWlnSm+wq2ppUARc8YaNokPUjiE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZN18 uniprotkb:O75530 intact:EBI-743256|ensembl:ENSP00000381840|uniprotkb:Q59FS5|uniprotkb:Q6ZN62|uniprotkb:Q96BG3 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 psi-mi:aebp2_human(display_long)|uniprotkb:Adipocyte enhancer-binding protein 2(gene name synonym)|uniprotkb:AEBP2(gene name)|psi-mi:AEBP2(display_short) psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830755|imex:IM-21659-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000139154(gene)|interpro:IPR036236|ensembl:ENST00000398864(transcript)|go:"GO:0000785"(chromatin)|mint:Q6ZN18|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001107648.1|refseq:NP_694939.2|rcsb pdb:5WAI|rcsb pdb:5Y0U|rcsb pdb:5Y1U|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|reactome:R-HSA-3214841|refseq:NP_001253972.1|dip:DIP-58581N|uniprotkb:Q6ZN18(identity)|ddbj/embl/genbank:BC015624(identity)|entrezgene/locuslink:121536(identity) refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:O75530(identity)|entrezgene/locuslink:8726(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:mOY+NOTaqJlXjW8v6D3YPnfnfBU9606 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 intact-crc:B7EEE441A248FA49|rigid:dWlnSm+wq2ppUARc8YaNokPUjiE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZN18 uniprotkb:P01833 intact:EBI-743256|ensembl:ENSP00000381840|uniprotkb:Q59FS5|uniprotkb:Q6ZN62|uniprotkb:Q96BG3 intact:EBI-1052371|uniprotkb:Q68D81|uniprotkb:Q8IZY7|ensembl:ENSP00000348888 psi-mi:aebp2_human(display_long)|uniprotkb:Adipocyte enhancer-binding protein 2(gene name synonym)|uniprotkb:AEBP2(gene name)|psi-mi:AEBP2(display_short) psi-mi:pigr_human(display_long)|uniprotkb:Hepatocellular carcinoma-associated protein TB6(gene name synonym)|uniprotkb:PIGR(gene name)|psi-mi:PIGR(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830755|imex:IM-21659-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000139154(gene)|interpro:IPR036236|ensembl:ENST00000398864(transcript)|go:"GO:0000785"(chromatin)|mint:Q6ZN18|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001107648.1|refseq:NP_694939.2|rcsb pdb:5WAI|rcsb pdb:5Y0U|rcsb pdb:5Y1U|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|reactome:R-HSA-3214841|refseq:NP_001253972.1|dip:DIP-58581N|uniprotkb:Q6ZN18(identity)|ddbj/embl/genbank:BC015624(identity)|entrezgene/locuslink:121536(identity) refseq:NP_002635.2|refseq:XP_011507931.1|ensembl:ENSG00000162896(gene)|ensembl:ENST00000356495(transcript)|go:"GO:0001580"(detection of chemical stimulus involved in sensory perception of bitter taste)|go:"GO:0001792"(polymeric immunoglobulin receptor activity)|go:"GO:0001895"(retina homeostasis)|go:"GO:0002415"(immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0038093"(Fc receptor signaling pathway)|go:"GO:0043113"(receptor clustering)|go:"GO:0043235"(receptor complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071751"(secretory IgA immunoglobulin complex)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1XED|rcsb pdb:2OCW|rcsb pdb:3CHN|rcsb pdb:3CM9|rcsb pdb:5D4K|rcsb pdb:6KXS|rcsb pdb:6LX3|rcsb pdb:6LXW|rcsb pdb:6UE7|rcsb pdb:6UE8|rcsb pdb:6UE9|rcsb pdb:6UEA|rcsb pdb:7K0C|reactome:R-HSA-6798695|uniprotkb:P01833(identity)|entrezgene/locuslink:5284(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:mOY+NOTaqJlXjW8v6D3YPnfnfBU9606 rogid:qidY3KoxSMLEzEryHDcr9OZoXo49606 intact-crc:B7EEE441A248FA49|rigid:dWlnSm+wq2ppUARc8YaNokPUjiE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZN18 uniprotkb:Q15022 intact:EBI-743256|ensembl:ENSP00000381840|uniprotkb:Q59FS5|uniprotkb:Q6ZN62|uniprotkb:Q96BG3 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 psi-mi:aebp2_human(display_long)|uniprotkb:Adipocyte enhancer-binding protein 2(gene name synonym)|uniprotkb:AEBP2(gene name)|psi-mi:AEBP2(display_short) psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830755|imex:IM-21659-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000139154(gene)|interpro:IPR036236|ensembl:ENST00000398864(transcript)|go:"GO:0000785"(chromatin)|mint:Q6ZN18|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001107648.1|refseq:NP_694939.2|rcsb pdb:5WAI|rcsb pdb:5Y0U|rcsb pdb:5Y1U|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|reactome:R-HSA-3214841|refseq:NP_001253972.1|dip:DIP-58581N|uniprotkb:Q6ZN18(identity)|ddbj/embl/genbank:BC015624(identity)|entrezgene/locuslink:121536(identity) dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:Q15022(identity)|entrezgene/locuslink:23512(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:mOY+NOTaqJlXjW8v6D3YPnfnfBU9606 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 intact-crc:B7EEE441A248FA49|rigid:dWlnSm+wq2ppUARc8YaNokPUjiE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZN18 uniprotkb:Q09028 intact:EBI-743256|ensembl:ENSP00000381840|uniprotkb:Q59FS5|uniprotkb:Q6ZN62|uniprotkb:Q96BG3 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 psi-mi:aebp2_human(display_long)|uniprotkb:Adipocyte enhancer-binding protein 2(gene name synonym)|uniprotkb:AEBP2(gene name)|psi-mi:AEBP2(display_short) psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830755|imex:IM-21659-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000139154(gene)|interpro:IPR036236|ensembl:ENST00000398864(transcript)|go:"GO:0000785"(chromatin)|mint:Q6ZN18|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001107648.1|refseq:NP_694939.2|rcsb pdb:5WAI|rcsb pdb:5Y0U|rcsb pdb:5Y1U|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|reactome:R-HSA-3214841|refseq:NP_001253972.1|dip:DIP-58581N|uniprotkb:Q6ZN18(identity)|ddbj/embl/genbank:BC015624(identity)|entrezgene/locuslink:121536(identity) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|entrezgene/locuslink:5928(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:mOY+NOTaqJlXjW8v6D3YPnfnfBU9606 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 intact-crc:B7EEE441A248FA49|rigid:dWlnSm+wq2ppUARc8YaNokPUjiE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZN18 uniprotkb:Q92800 intact:EBI-743256|ensembl:ENSP00000381840|uniprotkb:Q59FS5|uniprotkb:Q6ZN62|uniprotkb:Q96BG3 intact:EBI-8830732|uniprotkb:B4E3R7|uniprotkb:O43287|uniprotkb:A6NCH6|uniprotkb:Q14459|uniprotkb:Q53XP3|uniprotkb:B4DSS2|uniprotkb:B4DIJ1|uniprotkb:B4DIZ7|ensembl:ENSP00000404658|ensembl:ENSP00000466924 psi-mi:aebp2_human(display_long)|uniprotkb:Adipocyte enhancer-binding protein 2(gene name synonym)|uniprotkb:AEBP2(gene name)|psi-mi:AEBP2(display_short) psi-mi:ezh1_human(display_long)|uniprotkb:ENX-2(gene name synonym)|uniprotkb:Enhancer of zeste homolog 1(gene name synonym)|uniprotkb:KIAA0388(gene name synonym)|uniprotkb:EZH1(gene name)|psi-mi:EZH1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830755|imex:IM-21659-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000139154(gene)|interpro:IPR036236|ensembl:ENST00000398864(transcript)|go:"GO:0000785"(chromatin)|mint:Q6ZN18|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001107648.1|refseq:NP_694939.2|rcsb pdb:5WAI|rcsb pdb:5Y0U|rcsb pdb:5Y1U|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|reactome:R-HSA-3214841|refseq:NP_001253972.1|dip:DIP-58581N|uniprotkb:Q6ZN18(identity)|ddbj/embl/genbank:BC015624(identity)|entrezgene/locuslink:121536(identity) refseq:NP_001308008.1|refseq:NP_001308010.1|refseq:NP_001308011.1|refseq:NP_001982.2|dip:DIP-58580N|ensembl:ENSG00000108799(gene)|ensembl:ENST00000428826(transcript)|ensembl:ENST00000592743(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0021766"(hippocampus development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0031507"(heterochromatin assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR021654|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR032926|interpro:IPR041343|interpro:IPR041355|interpro:IPR044438|mint:Q92800|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|uniprotkb:Q92800(identity)|entrezgene/locuslink:2145(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:mOY+NOTaqJlXjW8v6D3YPnfnfBU9606 rogid:qp3eqBCgiaoA6VSSyqpW1d9YKN49606 intact-crc:B7EEE441A248FA49|rigid:dWlnSm+wq2ppUARc8YaNokPUjiE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZN18 uniprotkb:Q16576 intact:EBI-743256|ensembl:ENSP00000381840|uniprotkb:Q59FS5|uniprotkb:Q6ZN62|uniprotkb:Q96BG3 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 psi-mi:aebp2_human(display_long)|uniprotkb:Adipocyte enhancer-binding protein 2(gene name synonym)|uniprotkb:AEBP2(gene name)|psi-mi:AEBP2(display_short) psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830755|imex:IM-21659-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000139154(gene)|interpro:IPR036236|ensembl:ENST00000398864(transcript)|go:"GO:0000785"(chromatin)|mint:Q6ZN18|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001107648.1|refseq:NP_694939.2|rcsb pdb:5WAI|rcsb pdb:5Y0U|rcsb pdb:5Y1U|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|reactome:R-HSA-3214841|refseq:NP_001253972.1|dip:DIP-58581N|uniprotkb:Q6ZN18(identity)|ddbj/embl/genbank:BC015624(identity)|entrezgene/locuslink:121536(identity) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|entrezgene/locuslink:5931(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:mOY+NOTaqJlXjW8v6D3YPnfnfBU9606 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 intact-crc:B7EEE441A248FA49|rigid:dWlnSm+wq2ppUARc8YaNokPUjiE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZN18 uniprotkb:Q9GZZ8 intact:EBI-743256|ensembl:ENSP00000381840|uniprotkb:Q59FS5|uniprotkb:Q6ZN62|uniprotkb:Q96BG3 intact:EBI-3623441|ensembl:ENSP00000257867 psi-mi:aebp2_human(display_long)|uniprotkb:Adipocyte enhancer-binding protein 2(gene name synonym)|uniprotkb:AEBP2(gene name)|psi-mi:AEBP2(display_short) psi-mi:lacrt_human(display_long)|uniprotkb:LACRT(gene name)|psi-mi:LACRT(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830755|imex:IM-21659-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000139154(gene)|interpro:IPR036236|ensembl:ENST00000398864(transcript)|go:"GO:0000785"(chromatin)|mint:Q6ZN18|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001107648.1|refseq:NP_694939.2|rcsb pdb:5WAI|rcsb pdb:5Y0U|rcsb pdb:5Y1U|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|reactome:R-HSA-3214841|refseq:NP_001253972.1|dip:DIP-58581N|uniprotkb:Q6ZN18(identity)|ddbj/embl/genbank:BC015624(identity)|entrezgene/locuslink:121536(identity) refseq:NP_150593.1|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0060054"(positive regulation of epithelial cell proliferation involved in wound healing)|go:"GO:0070075"(tear secretion)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|interpro:IPR033530|interpro:IPR043557|ensembl:ENSG00000135413(gene)|ensembl:ENST00000257867(transcript)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006473"(protein acetylation)|go:"GO:0008083"(growth factor activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030141"(secretory granule)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0033173"(calcineurin-NFAT signaling cascade)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043237"(laminin-1 binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050850"(positive regulation of calcium-mediated signaling)|uniprotkb:Q9GZZ8(identity)|entrezgene/locuslink:90070(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:mOY+NOTaqJlXjW8v6D3YPnfnfBU9606 rogid:pPe6jkneU4pZBt36lcsMn2XLbcg9606 intact-crc:B7EEE441A248FA49|rigid:dWlnSm+wq2ppUARc8YaNokPUjiE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZN18 uniprotkb:P12273 intact:EBI-743256|ensembl:ENSP00000381840|uniprotkb:Q59FS5|uniprotkb:Q6ZN62|uniprotkb:Q96BG3 intact:EBI-1049746|uniprotkb:A0A963|uniprotkb:A0A9C3|uniprotkb:A0A9F3|uniprotkb:A4D2I1|ensembl:ENSP00000291009 psi-mi:aebp2_human(display_long)|uniprotkb:Adipocyte enhancer-binding protein 2(gene name synonym)|uniprotkb:AEBP2(gene name)|psi-mi:AEBP2(display_short) psi-mi:pip_human(display_long)|uniprotkb:Prolactin-induced protein(gene name synonym)|uniprotkb:Secretory actin-binding protein(gene name synonym)|uniprotkb:Gross cystic disease fluid protein 15(gene name synonym)|uniprotkb:gp17(gene name synonym)|uniprotkb:PIP(gene name)|psi-mi:PIP(display_short)|uniprotkb:GCDFP15(gene name synonym)|uniprotkb:GPIP4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830755|imex:IM-21659-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000139154(gene)|interpro:IPR036236|ensembl:ENST00000398864(transcript)|go:"GO:0000785"(chromatin)|mint:Q6ZN18|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001107648.1|refseq:NP_694939.2|rcsb pdb:5WAI|rcsb pdb:5Y0U|rcsb pdb:5Y1U|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|reactome:R-HSA-3214841|refseq:NP_001253972.1|dip:DIP-58581N|uniprotkb:Q6ZN18(identity)|ddbj/embl/genbank:BC015624(identity)|entrezgene/locuslink:121536(identity) refseq:NP_002643.1|ensembl:ENSG00000159763(gene)|ensembl:ENST00000291009(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0003779"(actin binding)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0006508"(proteolysis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019864"(IgG binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|interpro:IPR007990(Seminal vesicle autoantigen)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|mint:P12273|rcsb pdb:3ES6|reactome:R-HSA-5223345|go:"GO:0001580"(detection of chemical stimulus involved in sensory perception of bitter taste)|uniprotkb:P12273(identity)|entrezgene/locuslink:5304(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:mOY+NOTaqJlXjW8v6D3YPnfnfBU9606 rogid:/OC16zeRzFp520uPPLHh+WekPPc9606 intact-crc:B7EEE441A248FA49|rigid:dWlnSm+wq2ppUARc8YaNokPUjiE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZN18 uniprotkb:O75556 intact:EBI-743256|ensembl:ENSP00000381840|uniprotkb:Q59FS5|uniprotkb:Q6ZN62|uniprotkb:Q96BG3 intact:EBI-8830751|ensembl:ENSP00000244930 psi-mi:aebp2_human(display_long)|uniprotkb:Adipocyte enhancer-binding protein 2(gene name synonym)|uniprotkb:AEBP2(gene name)|psi-mi:AEBP2(display_short) psi-mi:sg2a1_human(display_long)|uniprotkb:LIPHC(gene name synonym)|uniprotkb:Lacryglobin(gene name synonym)|uniprotkb:Lipophilin-C(gene name synonym)|uniprotkb:MGB2(gene name synonym)|uniprotkb:Mammaglobin-2(gene name synonym)|uniprotkb:Secretoglobin family 2A member 1(gene name synonym)|uniprotkb:UGB3(gene name synonym)|uniprotkb:SCGB2A1(gene name)|psi-mi:SCGB2A1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830755|imex:IM-21659-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000139154(gene)|interpro:IPR036236|ensembl:ENST00000398864(transcript)|go:"GO:0000785"(chromatin)|mint:Q6ZN18|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001107648.1|refseq:NP_694939.2|rcsb pdb:5WAI|rcsb pdb:5Y0U|rcsb pdb:5Y1U|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|reactome:R-HSA-3214841|refseq:NP_001253972.1|dip:DIP-58581N|uniprotkb:Q6ZN18(identity)|ddbj/embl/genbank:BC015624(identity)|entrezgene/locuslink:121536(identity) refseq:NP_002398.1|ensembl:ENSG00000124939(gene)|ensembl:ENST00000244930(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0030521"(androgen receptor signaling pathway)|interpro:IPR016126(Secretoglobin)|interpro:IPR035960|uniprotkb:O75556(identity)|entrezgene/locuslink:4246(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:mOY+NOTaqJlXjW8v6D3YPnfnfBU9606 rogid:w+3NKAb7Len68q3aS4Re1qKbOac9606 intact-crc:B7EEE441A248FA49|rigid:dWlnSm+wq2ppUARc8YaNokPUjiE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXJ9 uniprotkb:Q92560 intact:EBI-1646500|uniprotkb:Q5JWS9|uniprotkb:Q8IYY7|uniprotkb:Q9H466|uniprotkb:Q9NQF8|uniprotkb:Q9UFJ0|uniprotkb:Q9UFP8|uniprotkb:Q9Y2I4|uniprotkb:B2RP59|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978 intact:EBI-1791447|uniprotkb:Q6LEM0|uniprotkb:Q7Z5E8|uniprotkb:A8K993|intact:EBI-2558090|ensembl:ENSP00000417132 psi-mi:asxl1_human(display_long)|uniprotkb:ASXL1(gene name)|psi-mi:ASXL1(display_short)|uniprotkb:KIAA0978(gene name synonym)|uniprotkb:Additional sex combs-like protein 1(gene name synonym) psi-mi:bap1_human(display_long)|uniprotkb:BAP1(gene name)|psi-mi:BAP1(display_short)|uniprotkb:KIAA0272(gene name synonym)|uniprotkb:hucep-6(orf name)|uniprotkb:BRCA1-associated protein 1(gene name synonym)|uniprotkb:Cerebral protein 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830826|imex:IM-21659-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056153.2|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978|dip:DIP-46910N|ensembl:ENSG00000171456(gene)|ensembl:ENST00000375687(transcript)|ensembl:ENST00000613218(transcript)|ensembl:ENST00000620121(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035359"(negative regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0035564"(regulation of kidney size)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048538"(thymus development)|go:"GO:0048539"(bone marrow development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060430"(lung saccule development)|go:"GO:0072015"(glomerular visceral epithelial cell development)|interpro:IPR007759(DNA-directed RNA polymerase delta subunit)|interpro:IPR024811|interpro:IPR024815|interpro:IPR026905|interpro:IPR028020|interpro:IPR044867|reactome:R-HSA-5689603|go:"GO:0048386"(positive regulation of retinoic acid receptor signaling pathway)|uniprotkb:Q8IXJ9(identity)|ddbj/embl/genbank:BC064984(identity)|entrezgene/locuslink:171023(identity) dip:DIP-47004N|refseq:NP_004647.1|ensembl:ENSG00000163930(gene)|ensembl:ENST00000460680(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003682"(chromatin binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061519"(macrophage homeostasis)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q92560|reactome:R-HSA-5689603|reactome:R-HSA-5693565|uniprotkb:Q92560(identity)|entrezgene/locuslink:8314(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:6YpSgdOhNRawROUe3W0t72u6JfA9606 rogid:GMWdT1u5HUl29N+YgC/bCKTbxm49606 intact-crc:B2F8556456613C71|rigid:2KWLQz8VuDL+8Sry2JyimsDsRXU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXJ9 uniprotkb:P62333 intact:EBI-1646500|uniprotkb:Q5JWS9|uniprotkb:Q8IYY7|uniprotkb:Q9H466|uniprotkb:Q9NQF8|uniprotkb:Q9UFJ0|uniprotkb:Q9UFP8|uniprotkb:Q9Y2I4|uniprotkb:B2RP59|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978 intact:EBI-357669|uniprotkb:Q92524|uniprotkb:P49719|uniprotkb:Q6IBU3|uniprotkb:B2R975|ensembl:ENSP00000401802 psi-mi:asxl1_human(display_long)|uniprotkb:ASXL1(gene name)|psi-mi:ASXL1(display_short)|uniprotkb:KIAA0978(gene name synonym)|uniprotkb:Additional sex combs-like protein 1(gene name synonym) psi-mi:prs10_human(display_long)|uniprotkb:PSMC6(gene name)|psi-mi:PSMC6(display_short)|uniprotkb:SUG2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 6(gene name synonym)|uniprotkb:Proteasome subunit p42(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830826|imex:IM-21659-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056153.2|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978|dip:DIP-46910N|ensembl:ENSG00000171456(gene)|ensembl:ENST00000375687(transcript)|ensembl:ENST00000613218(transcript)|ensembl:ENST00000620121(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035359"(negative regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0035564"(regulation of kidney size)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048538"(thymus development)|go:"GO:0048539"(bone marrow development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060430"(lung saccule development)|go:"GO:0072015"(glomerular visceral epithelial cell development)|interpro:IPR007759(DNA-directed RNA polymerase delta subunit)|interpro:IPR024811|interpro:IPR024815|interpro:IPR026905|interpro:IPR028020|interpro:IPR044867|reactome:R-HSA-5689603|go:"GO:0048386"(positive regulation of retinoic acid receptor signaling pathway)|uniprotkb:Q8IXJ9(identity)|ddbj/embl/genbank:BC064984(identity)|entrezgene/locuslink:171023(identity) refseq:NP_002797.3|ensembl:ENST00000445930(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000100519(gene)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR032501|interpro:IPR035263|interpro:IPR041569|mint:P62333|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-75815|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-174184|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|dip:DIP-38150N|uniprotkb:P62333(identity)|entrezgene/locuslink:5706(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:6YpSgdOhNRawROUe3W0t72u6JfA9606 rogid:QE8jzSEp1bpzhOi/oAAnV18QK249606 intact-crc:B2F8556456613C71|rigid:2KWLQz8VuDL+8Sry2JyimsDsRXU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXJ9 uniprotkb:P35998 intact:EBI-1646500|uniprotkb:Q5JWS9|uniprotkb:Q8IYY7|uniprotkb:Q9H466|uniprotkb:Q9NQF8|uniprotkb:Q9UFJ0|uniprotkb:Q9UFP8|uniprotkb:Q9Y2I4|uniprotkb:B2RP59|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978 intact:EBI-359710|uniprotkb:B7Z5E2|uniprotkb:A4D0Q1|uniprotkb:Q3LIA5|uniprotkb:Q9UDI3|ensembl:ENSP00000292644|ensembl:ENSP00000391211|ensembl:ENSP00000502939|ensembl:ENSP00000503179|ensembl:ENSP00000504608 psi-mi:asxl1_human(display_long)|uniprotkb:ASXL1(gene name)|psi-mi:ASXL1(display_short)|uniprotkb:KIAA0978(gene name synonym)|uniprotkb:Additional sex combs-like protein 1(gene name synonym) psi-mi:prs7_human(display_long)|uniprotkb:PSMC2(gene name)|psi-mi:PSMC2(display_short)|uniprotkb:MSS1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 2(gene name synonym)|uniprotkb:Protein MSS1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830826|imex:IM-21659-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056153.2|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978|dip:DIP-46910N|ensembl:ENSG00000171456(gene)|ensembl:ENST00000375687(transcript)|ensembl:ENST00000613218(transcript)|ensembl:ENST00000620121(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035359"(negative regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0035564"(regulation of kidney size)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048538"(thymus development)|go:"GO:0048539"(bone marrow development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060430"(lung saccule development)|go:"GO:0072015"(glomerular visceral epithelial cell development)|interpro:IPR007759(DNA-directed RNA polymerase delta subunit)|interpro:IPR024811|interpro:IPR024815|interpro:IPR026905|interpro:IPR028020|interpro:IPR044867|reactome:R-HSA-5689603|go:"GO:0048386"(positive regulation of retinoic acid receptor signaling pathway)|uniprotkb:Q8IXJ9(identity)|ddbj/embl/genbank:BC064984(identity)|entrezgene/locuslink:171023(identity) refseq:NP_001191382.1|refseq:NP_002794.1|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR035245|interpro:IPR041569|mint:P35998|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|interpro:IPR003960(AAA ATPase, conserved site)|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|ensembl:ENSG00000161057(gene)|ensembl:ENST00000292644(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|ensembl:ENST00000435765(transcript)|ensembl:ENST00000678493(transcript)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|ensembl:ENST00000679205(transcript)|ensembl:ENST00000679341(transcript)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0043197"(dendritic spine)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5VHQ|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5610780|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|dip:DIP-27554N|uniprotkb:P35998(identity)|entrezgene/locuslink:5701(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:6YpSgdOhNRawROUe3W0t72u6JfA9606 rogid:ahQfjPKywP5DWNq3FB5XCjuqkJ09606 intact-crc:B2F8556456613C71|rigid:2KWLQz8VuDL+8Sry2JyimsDsRXU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXJ9 uniprotkb:Q01167 intact:EBI-1646500|uniprotkb:Q5JWS9|uniprotkb:Q8IYY7|uniprotkb:Q9H466|uniprotkb:Q9NQF8|uniprotkb:Q9UFJ0|uniprotkb:Q9UFP8|uniprotkb:Q9Y2I4|uniprotkb:B2RP59|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978 intact:EBI-2509991|intact:EBI-28976610|ensembl:ENSP00000335677|uniprotkb:Q13624|uniprotkb:Q13623|uniprotkb:A6NEP5|uniprotkb:Q13622 psi-mi:asxl1_human(display_long)|uniprotkb:ASXL1(gene name)|psi-mi:ASXL1(display_short)|uniprotkb:KIAA0978(gene name synonym)|uniprotkb:Additional sex combs-like protein 1(gene name synonym) psi-mi:foxk2_human(display_long)|uniprotkb:G/T-mismatch specific binding protein(gene name synonym)|uniprotkb:FOXK2(gene name)|psi-mi:FOXK2(display_short)|uniprotkb:ILF(gene name synonym)|uniprotkb:ILF1(gene name synonym)|uniprotkb:Interleukin enhancer-binding factor 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830826|imex:IM-21659-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056153.2|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978|dip:DIP-46910N|ensembl:ENSG00000171456(gene)|ensembl:ENST00000375687(transcript)|ensembl:ENST00000613218(transcript)|ensembl:ENST00000620121(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035359"(negative regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0035564"(regulation of kidney size)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048538"(thymus development)|go:"GO:0048539"(bone marrow development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060430"(lung saccule development)|go:"GO:0072015"(glomerular visceral epithelial cell development)|interpro:IPR007759(DNA-directed RNA polymerase delta subunit)|interpro:IPR024811|interpro:IPR024815|interpro:IPR026905|interpro:IPR028020|interpro:IPR044867|reactome:R-HSA-5689603|go:"GO:0048386"(positive regulation of retinoic acid receptor signaling pathway)|uniprotkb:Q8IXJ9(identity)|ddbj/embl/genbank:BC064984(identity)|entrezgene/locuslink:171023(identity) ensembl:ENSG00000141568(gene)|ensembl:ENST00000335255(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0042594"(response to starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR018122|go:"GO:0061621"(canonical glycolysis)|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|mint:Q01167|rcsb pdb:1JXS|rcsb pdb:2C6Y|reactome:R-HSA-5689603|ensembl:ENSP00000335677|ensembl:ENST00000473637|ensembl:ENSP00000436108|refseq:NP_004505.2|uniprotkb:Q01167(identity)|entrezgene/locuslink:3607(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:6YpSgdOhNRawROUe3W0t72u6JfA9606 rogid:mGYtlnM3enVAuU82j5hQ0sui3F49606 intact-crc:B2F8556456613C71|rigid:2KWLQz8VuDL+8Sry2JyimsDsRXU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXJ9 uniprotkb:Q96DN6 intact:EBI-1646500|uniprotkb:Q5JWS9|uniprotkb:Q8IYY7|uniprotkb:Q9H466|uniprotkb:Q9NQF8|uniprotkb:Q9UFJ0|uniprotkb:Q9UFP8|uniprotkb:Q9Y2I4|uniprotkb:B2RP59|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978 intact:EBI-719591|uniprotkb:Q8N3M0|uniprotkb:Q8NA81|uniprotkb:Q96Q00|ensembl:ENSP00000347896 psi-mi:asxl1_human(display_long)|uniprotkb:ASXL1(gene name)|psi-mi:ASXL1(display_short)|uniprotkb:KIAA0978(gene name synonym)|uniprotkb:Additional sex combs-like protein 1(gene name synonym) psi-mi:mbd6_human(display_long)|uniprotkb:Methyl-CpG-binding protein MBD6(gene name synonym)|uniprotkb:MBD6(gene name)|psi-mi:MBD6(display_short)|uniprotkb:KIAA1887(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830826|imex:IM-21659-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056153.2|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978|dip:DIP-46910N|ensembl:ENSG00000171456(gene)|ensembl:ENST00000375687(transcript)|ensembl:ENST00000613218(transcript)|ensembl:ENST00000620121(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035359"(negative regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0035564"(regulation of kidney size)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048538"(thymus development)|go:"GO:0048539"(bone marrow development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060430"(lung saccule development)|go:"GO:0072015"(glomerular visceral epithelial cell development)|interpro:IPR007759(DNA-directed RNA polymerase delta subunit)|interpro:IPR024811|interpro:IPR024815|interpro:IPR026905|interpro:IPR028020|interpro:IPR044867|reactome:R-HSA-5689603|go:"GO:0048386"(positive regulation of retinoic acid receptor signaling pathway)|uniprotkb:Q8IXJ9(identity)|ddbj/embl/genbank:BC064984(identity)|entrezgene/locuslink:171023(identity) refseq:NP_443129.3|ensembl:ENSG00000166987(gene)|ensembl:ENST00000355673(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0010369"(chromocenter)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR037385|reactome:R-HSA-5689603|uniprotkb:Q96DN6(identity)|entrezgene/locuslink:114785(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:6YpSgdOhNRawROUe3W0t72u6JfA9606 rogid:b/lOJGEiC6RxM4s3rq8nXw6zmjE9606 intact-crc:B2F8556456613C71|rigid:2KWLQz8VuDL+8Sry2JyimsDsRXU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXJ9 uniprotkb:Q9P267 intact:EBI-1646500|uniprotkb:Q5JWS9|uniprotkb:Q8IYY7|uniprotkb:Q9H466|uniprotkb:Q9NQF8|uniprotkb:Q9UFJ0|uniprotkb:Q9UFP8|uniprotkb:Q9Y2I4|uniprotkb:B2RP59|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978 intact:EBI-311373|uniprotkb:A5HMQ4|uniprotkb:A7E2B1|uniprotkb:Q9NUV6|uniprotkb:Q53SR1|ensembl:ENSP00000386049 psi-mi:asxl1_human(display_long)|uniprotkb:ASXL1(gene name)|psi-mi:ASXL1(display_short)|uniprotkb:KIAA0978(gene name synonym)|uniprotkb:Additional sex combs-like protein 1(gene name synonym) psi-mi:mbd5_human(display_long)|uniprotkb:MBD5(gene name)|psi-mi:MBD5(display_short)|uniprotkb:KIAA1461(gene name synonym)|uniprotkb:Methyl-CpG-binding protein MBD5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830826|imex:IM-21659-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056153.2|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978|dip:DIP-46910N|ensembl:ENSG00000171456(gene)|ensembl:ENST00000375687(transcript)|ensembl:ENST00000613218(transcript)|ensembl:ENST00000620121(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035359"(negative regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0035564"(regulation of kidney size)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048538"(thymus development)|go:"GO:0048539"(bone marrow development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060430"(lung saccule development)|go:"GO:0072015"(glomerular visceral epithelial cell development)|interpro:IPR007759(DNA-directed RNA polymerase delta subunit)|interpro:IPR024811|interpro:IPR024815|interpro:IPR026905|interpro:IPR028020|interpro:IPR044867|reactome:R-HSA-5689603|go:"GO:0048386"(positive regulation of retinoic acid receptor signaling pathway)|uniprotkb:Q8IXJ9(identity)|ddbj/embl/genbank:BC064984(identity)|entrezgene/locuslink:171023(identity) refseq:NP_060798.2|ensembl:ENSG00000204406(gene)|ensembl:ENST00000407073(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0007399"(nervous system development)|go:"GO:0010369"(chromocenter)|go:"GO:0030496"(midbody)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0050795"(regulation of behavior)|go:"GO:0060399"(positive regulation of growth hormone receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000313(PWWP)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR037385|reactome:R-HSA-5689603|uniprotkb:Q9P267(identity)|entrezgene/locuslink:55777(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:6YpSgdOhNRawROUe3W0t72u6JfA9606 rogid:3h6aGO+XvdJ82StRzy6BtzD6IPI9606 intact-crc:B2F8556456613C71|rigid:2KWLQz8VuDL+8Sry2JyimsDsRXU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXJ9 uniprotkb:Q9BQE3 intact:EBI-1646500|uniprotkb:Q5JWS9|uniprotkb:Q8IYY7|uniprotkb:Q9H466|uniprotkb:Q9NQF8|uniprotkb:Q9UFJ0|uniprotkb:Q9UFP8|uniprotkb:Q9Y2I4|uniprotkb:B2RP59|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:asxl1_human(display_long)|uniprotkb:ASXL1(gene name)|psi-mi:ASXL1(display_short)|uniprotkb:KIAA0978(gene name synonym)|uniprotkb:Additional sex combs-like protein 1(gene name synonym) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830826|imex:IM-21659-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056153.2|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978|dip:DIP-46910N|ensembl:ENSG00000171456(gene)|ensembl:ENST00000375687(transcript)|ensembl:ENST00000613218(transcript)|ensembl:ENST00000620121(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035359"(negative regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0035564"(regulation of kidney size)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048538"(thymus development)|go:"GO:0048539"(bone marrow development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060430"(lung saccule development)|go:"GO:0072015"(glomerular visceral epithelial cell development)|interpro:IPR007759(DNA-directed RNA polymerase delta subunit)|interpro:IPR024811|interpro:IPR024815|interpro:IPR026905|interpro:IPR028020|interpro:IPR044867|reactome:R-HSA-5689603|go:"GO:0048386"(positive regulation of retinoic acid receptor signaling pathway)|uniprotkb:Q8IXJ9(identity)|ddbj/embl/genbank:BC064984(identity)|entrezgene/locuslink:171023(identity) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1|uniprotkb:Q9BQE3(identity)|entrezgene/locuslink:84790(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:6YpSgdOhNRawROUe3W0t72u6JfA9606 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:B2F8556456613C71|rigid:2KWLQz8VuDL+8Sry2JyimsDsRXU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXJ9 uniprotkb:O15294 intact:EBI-1646500|uniprotkb:Q5JWS9|uniprotkb:Q8IYY7|uniprotkb:Q9H466|uniprotkb:Q9NQF8|uniprotkb:Q9UFJ0|uniprotkb:Q9UFP8|uniprotkb:Q9Y2I4|uniprotkb:B2RP59|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 psi-mi:asxl1_human(display_long)|uniprotkb:ASXL1(gene name)|psi-mi:ASXL1(display_short)|uniprotkb:KIAA0978(gene name synonym)|uniprotkb:Additional sex combs-like protein 1(gene name synonym) psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830826|imex:IM-21659-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056153.2|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978|dip:DIP-46910N|ensembl:ENSG00000171456(gene)|ensembl:ENST00000375687(transcript)|ensembl:ENST00000613218(transcript)|ensembl:ENST00000620121(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035359"(negative regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0035564"(regulation of kidney size)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048538"(thymus development)|go:"GO:0048539"(bone marrow development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060430"(lung saccule development)|go:"GO:0072015"(glomerular visceral epithelial cell development)|interpro:IPR007759(DNA-directed RNA polymerase delta subunit)|interpro:IPR024811|interpro:IPR024815|interpro:IPR026905|interpro:IPR028020|interpro:IPR044867|reactome:R-HSA-5689603|go:"GO:0048386"(positive regulation of retinoic acid receptor signaling pathway)|uniprotkb:Q8IXJ9(identity)|ddbj/embl/genbank:BC064984(identity)|entrezgene/locuslink:171023(identity) refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N|uniprotkb:O15294(identity)|entrezgene/locuslink:8473(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:6YpSgdOhNRawROUe3W0t72u6JfA9606 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 intact-crc:B2F8556456613C71|rigid:2KWLQz8VuDL+8Sry2JyimsDsRXU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXJ9 uniprotkb:P62195 intact:EBI-1646500|uniprotkb:Q5JWS9|uniprotkb:Q8IYY7|uniprotkb:Q9H466|uniprotkb:Q9NQF8|uniprotkb:Q9UFJ0|uniprotkb:Q9UFP8|uniprotkb:Q9Y2I4|uniprotkb:B2RP59|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978 intact:EBI-357745|uniprotkb:O35051|uniprotkb:O43208|uniprotkb:P52915|uniprotkb:P47210|uniprotkb:P52916|uniprotkb:A8K763|uniprotkb:A8K3Z3|ensembl:ENSP00000310572 psi-mi:asxl1_human(display_long)|uniprotkb:ASXL1(gene name)|psi-mi:ASXL1(display_short)|uniprotkb:KIAA0978(gene name synonym)|uniprotkb:Additional sex combs-like protein 1(gene name synonym) psi-mi:prs8_human(display_long)|uniprotkb:PSMC5(gene name)|psi-mi:PSMC5(display_short)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 5(gene name synonym)|uniprotkb:Proteasome subunit p45(gene name synonym)|uniprotkb:p45/SUG(gene name synonym)|uniprotkb:Thyroid hormone receptor-interacting protein 1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830826|imex:IM-21659-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056153.2|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978|dip:DIP-46910N|ensembl:ENSG00000171456(gene)|ensembl:ENST00000375687(transcript)|ensembl:ENST00000613218(transcript)|ensembl:ENST00000620121(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035359"(negative regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0035564"(regulation of kidney size)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048538"(thymus development)|go:"GO:0048539"(bone marrow development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060430"(lung saccule development)|go:"GO:0072015"(glomerular visceral epithelial cell development)|interpro:IPR007759(DNA-directed RNA polymerase delta subunit)|interpro:IPR024811|interpro:IPR024815|interpro:IPR026905|interpro:IPR028020|interpro:IPR044867|reactome:R-HSA-5689603|go:"GO:0048386"(positive regulation of retinoic acid receptor signaling pathway)|uniprotkb:Q8IXJ9(identity)|ddbj/embl/genbank:BC064984(identity)|entrezgene/locuslink:171023(identity) refseq:NP_001186092.1|refseq:NP_002796.4|reactome:R-HSA-195253|ensembl:ENSG00000087191(gene)|ensembl:ENST00000310144(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031531"(thyrotropin-releasing hormone receptor binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|mint:P62195|rcsb pdb:2KRK|rcsb pdb:3KW6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-36645N|uniprotkb:P62195(identity)|entrezgene/locuslink:5705(identity) psi-mi:"MI:0469"(intact) - crc64:29C6410C4A85A7F7 figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:6YpSgdOhNRawROUe3W0t72u6JfA9606 rogid:zgUTOX/O4m86U/Nf+pnT7u0m0gY9606 intact-crc:B2F8556456613C71|rigid:2KWLQz8VuDL+8Sry2JyimsDsRXU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXJ9 uniprotkb:P43686 intact:EBI-1646500|uniprotkb:Q5JWS9|uniprotkb:Q8IYY7|uniprotkb:Q9H466|uniprotkb:Q9NQF8|uniprotkb:Q9UFJ0|uniprotkb:Q9UFP8|uniprotkb:Q9Y2I4|uniprotkb:B2RP59|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978 intact:EBI-743997|uniprotkb:Q96FV5|uniprotkb:Q9UBM3|uniprotkb:Q9UEX3|ensembl:ENSP00000157812|ensembl:ENSP00000487367 psi-mi:asxl1_human(display_long)|uniprotkb:ASXL1(gene name)|psi-mi:ASXL1(display_short)|uniprotkb:KIAA0978(gene name synonym)|uniprotkb:Additional sex combs-like protein 1(gene name synonym) psi-mi:prs6b_human(display_long)|uniprotkb:Proteasome 26S subunit ATPase 4(gene name synonym)|uniprotkb:MB67-interacting protein(gene name synonym)|uniprotkb:PSMC4(gene name)|psi-mi:PSMC4(display_short)|uniprotkb:TBP7(gene name synonym)|uniprotkb:MIP224(gene name synonym)|uniprotkb:Tat-binding protein 7(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830826|imex:IM-21659-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056153.2|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978|dip:DIP-46910N|ensembl:ENSG00000171456(gene)|ensembl:ENST00000375687(transcript)|ensembl:ENST00000613218(transcript)|ensembl:ENST00000620121(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035359"(negative regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0035564"(regulation of kidney size)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048538"(thymus development)|go:"GO:0048539"(bone marrow development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060430"(lung saccule development)|go:"GO:0072015"(glomerular visceral epithelial cell development)|interpro:IPR007759(DNA-directed RNA polymerase delta subunit)|interpro:IPR024811|interpro:IPR024815|interpro:IPR026905|interpro:IPR028020|interpro:IPR044867|reactome:R-HSA-5689603|go:"GO:0048386"(positive regulation of retinoic acid receptor signaling pathway)|uniprotkb:Q8IXJ9(identity)|ddbj/embl/genbank:BC064984(identity)|entrezgene/locuslink:171023(identity) refseq:NP_006494.1|refseq:NP_694546.1|dip:DIP-29274N|ensembl:ENSG00000013275(gene)|ensembl:ENSG00000281221(gene)|ensembl:ENST00000157812(transcript)|ensembl:ENST00000629691(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045202"(synapse)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035256|interpro:IPR041569|mint:P43686|rcsb pdb:2DVW|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-69601|uniprotkb:P43686(identity)|entrezgene/locuslink:5704(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:6YpSgdOhNRawROUe3W0t72u6JfA9606 rogid:ZwHUFX8vJa8IPZi000dHiFtUtlM9606 intact-crc:B2F8556456613C71|rigid:2KWLQz8VuDL+8Sry2JyimsDsRXU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXJ9 uniprotkb:P51610 intact:EBI-1646500|uniprotkb:Q5JWS9|uniprotkb:Q8IYY7|uniprotkb:Q9H466|uniprotkb:Q9NQF8|uniprotkb:Q9UFJ0|uniprotkb:Q9UFP8|uniprotkb:Q9Y2I4|uniprotkb:B2RP59|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978 intact:EBI-396176|intact:EBI-2832627|uniprotkb:Q6P4G5|intact:EBI-12037257|intact:EBI-14324845|ensembl:ENSP00000309555|intact:EBI-12980473 psi-mi:asxl1_human(display_long)|uniprotkb:ASXL1(gene name)|psi-mi:ASXL1(display_short)|uniprotkb:KIAA0978(gene name synonym)|uniprotkb:Additional sex combs-like protein 1(gene name synonym) psi-mi:hcfc1_human(display_long)|uniprotkb:HCFC1(gene name)|psi-mi:HCFC1(display_short)|uniprotkb:HCF1(gene name synonym)|uniprotkb:C1 factor(gene name synonym)|uniprotkb:VP16 accessory protein(gene name synonym)|uniprotkb:VCAF(gene name synonym)|uniprotkb:CFF(gene name synonym)|uniprotkb:HFC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830826|imex:IM-21659-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056153.2|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978|dip:DIP-46910N|ensembl:ENSG00000171456(gene)|ensembl:ENST00000375687(transcript)|ensembl:ENST00000613218(transcript)|ensembl:ENST00000620121(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035359"(negative regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0035564"(regulation of kidney size)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048538"(thymus development)|go:"GO:0048539"(bone marrow development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060430"(lung saccule development)|go:"GO:0072015"(glomerular visceral epithelial cell development)|interpro:IPR007759(DNA-directed RNA polymerase delta subunit)|interpro:IPR024811|interpro:IPR024815|interpro:IPR026905|interpro:IPR028020|interpro:IPR044867|reactome:R-HSA-5689603|go:"GO:0048386"(positive regulation of retinoic acid receptor signaling pathway)|uniprotkb:Q8IXJ9(identity)|ddbj/embl/genbank:BC064984(identity)|entrezgene/locuslink:171023(identity) refseq:NP_005325.2|refseq:XP_006724879.1|rcsb pdb:6MA1|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|reactome:R-HSA-2151201|reactome:R-HSA-3214847|reactome:R-HSA-5689603|ensembl:ENSG00000172534(gene)|ensembl:ENST00000310441(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019046"(release from viral latency)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR036116|interpro:IPR037854|interpro:IPR043536|mint:P51610|rcsb pdb:4GO6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:5LWV|dip:DIP-32955N|uniprotkb:P51610(identity)|entrezgene/locuslink:3054(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:6YpSgdOhNRawROUe3W0t72u6JfA9606 rogid:RzsCRe9l6md3DI87H4ZgdR9oBMI9606 intact-crc:B2F8556456613C71|rigid:2KWLQz8VuDL+8Sry2JyimsDsRXU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXJ9 uniprotkb:P85037 intact:EBI-1646500|uniprotkb:Q5JWS9|uniprotkb:Q8IYY7|uniprotkb:Q9H466|uniprotkb:Q9NQF8|uniprotkb:Q9UFJ0|uniprotkb:Q9UFP8|uniprotkb:Q9Y2I4|uniprotkb:B2RP59|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978 intact:EBI-2509974|ensembl:ENSP00000328720 psi-mi:asxl1_human(display_long)|uniprotkb:ASXL1(gene name)|psi-mi:ASXL1(display_short)|uniprotkb:KIAA0978(gene name synonym)|uniprotkb:Additional sex combs-like protein 1(gene name synonym) psi-mi:foxk1_human(display_long)|uniprotkb:FOXK1(gene name)|psi-mi:FOXK1(display_short)|uniprotkb:MNF(gene name synonym)|uniprotkb:Myocyte nuclear factor(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830826|imex:IM-21659-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056153.2|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978|dip:DIP-46910N|ensembl:ENSG00000171456(gene)|ensembl:ENST00000375687(transcript)|ensembl:ENST00000613218(transcript)|ensembl:ENST00000620121(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035359"(negative regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0035564"(regulation of kidney size)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048538"(thymus development)|go:"GO:0048539"(bone marrow development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060430"(lung saccule development)|go:"GO:0072015"(glomerular visceral epithelial cell development)|interpro:IPR007759(DNA-directed RNA polymerase delta subunit)|interpro:IPR024811|interpro:IPR024815|interpro:IPR026905|interpro:IPR028020|interpro:IPR044867|reactome:R-HSA-5689603|go:"GO:0048386"(positive regulation of retinoic acid receptor signaling pathway)|uniprotkb:Q8IXJ9(identity)|ddbj/embl/genbank:BC064984(identity)|entrezgene/locuslink:171023(identity) ensembl:ENSG00000164916(gene)|ensembl:ENST00000328914(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0042594"(response to starvation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5689603|refseq:XP_011513493.1|refseq:NP_001032242.1|uniprotkb:P85037(identity)|entrezgene/locuslink:221937(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:6YpSgdOhNRawROUe3W0t72u6JfA9606 rogid:ngoE3oNlIDGkTf1ZMYG4OQ6lvE09606 intact-crc:B2F8556456613C71|rigid:2KWLQz8VuDL+8Sry2JyimsDsRXU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXJ9 uniprotkb:P62891 intact:EBI-1646500|uniprotkb:Q5JWS9|uniprotkb:Q8IYY7|uniprotkb:Q9H466|uniprotkb:Q9NQF8|uniprotkb:Q9UFJ0|uniprotkb:Q9UFP8|uniprotkb:Q9Y2I4|uniprotkb:B2RP59|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978 intact:EBI-8830744|uniprotkb:P02404|uniprotkb:Q9BYF2|uniprotkb:P39025|ensembl:ENSP00000355315 psi-mi:asxl1_human(display_long)|uniprotkb:ASXL1(gene name)|psi-mi:ASXL1(display_short)|uniprotkb:KIAA0978(gene name synonym)|uniprotkb:Additional sex combs-like protein 1(gene name synonym) psi-mi:rl39_human(display_long)|uniprotkb:RPL39(gene name)|psi-mi:RPL39(display_short)|uniprotkb:Large ribosomal subunit protein eL39(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830826|imex:IM-21659-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056153.2|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978|dip:DIP-46910N|ensembl:ENSG00000171456(gene)|ensembl:ENST00000375687(transcript)|ensembl:ENST00000613218(transcript)|ensembl:ENST00000620121(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035359"(negative regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0035564"(regulation of kidney size)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048538"(thymus development)|go:"GO:0048539"(bone marrow development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060430"(lung saccule development)|go:"GO:0072015"(glomerular visceral epithelial cell development)|interpro:IPR007759(DNA-directed RNA polymerase delta subunit)|interpro:IPR024811|interpro:IPR024815|interpro:IPR026905|interpro:IPR028020|interpro:IPR044867|reactome:R-HSA-5689603|go:"GO:0048386"(positive regulation of retinoic acid receptor signaling pathway)|uniprotkb:Q8IXJ9(identity)|ddbj/embl/genbank:BC064984(identity)|entrezgene/locuslink:171023(identity) refseq:NP_000991.1|rcsb pdb:4V6X|ensembl:ENSG00000198918(gene)|ensembl:ENST00000361575(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000077(Ribosomal protein L39e)|interpro:IPR020083|interpro:IPR023626|rcsb pdb:4UG0|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|uniprotkb:P62891(identity)|entrezgene/locuslink:6170(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:6YpSgdOhNRawROUe3W0t72u6JfA9606 rogid:AZus2dxwJsTxAOwnJ93E2yhasbo9606 intact-crc:B2F8556456613C71|rigid:2KWLQz8VuDL+8Sry2JyimsDsRXU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXJ9 uniprotkb:P48556 intact:EBI-1646500|uniprotkb:Q5JWS9|uniprotkb:Q8IYY7|uniprotkb:Q9H466|uniprotkb:Q9NQF8|uniprotkb:Q9UFJ0|uniprotkb:Q9UFP8|uniprotkb:Q9Y2I4|uniprotkb:B2RP59|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978 intact:EBI-359304|uniprotkb:Q6P1L7|uniprotkb:B4DX18|ensembl:ENSP00000215071|ensembl:ENSP00000481136 psi-mi:asxl1_human(display_long)|uniprotkb:ASXL1(gene name)|psi-mi:ASXL1(display_short)|uniprotkb:KIAA0978(gene name synonym)|uniprotkb:Additional sex combs-like protein 1(gene name synonym) psi-mi:psmd8_human(display_long)|uniprotkb:PSMD8(gene name)|psi-mi:PSMD8(display_short)|uniprotkb:26S proteasome regulatory subunit S14(gene name synonym)|uniprotkb:p31(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN12(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830826|imex:IM-21659-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056153.2|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978|dip:DIP-46910N|ensembl:ENSG00000171456(gene)|ensembl:ENST00000375687(transcript)|ensembl:ENST00000613218(transcript)|ensembl:ENST00000620121(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035359"(negative regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0035564"(regulation of kidney size)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048538"(thymus development)|go:"GO:0048539"(bone marrow development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060430"(lung saccule development)|go:"GO:0072015"(glomerular visceral epithelial cell development)|interpro:IPR007759(DNA-directed RNA polymerase delta subunit)|interpro:IPR024811|interpro:IPR024815|interpro:IPR026905|interpro:IPR028020|interpro:IPR044867|reactome:R-HSA-5689603|go:"GO:0048386"(positive regulation of retinoic acid receptor signaling pathway)|uniprotkb:Q8IXJ9(identity)|ddbj/embl/genbank:BC064984(identity)|entrezgene/locuslink:171023(identity) refseq:NP_002803.2|ensembl:ENSG00000099341(gene)|ensembl:ENST00000215071(transcript)|ensembl:ENST00000620216(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR006746(26S proteasome non-ATPase regulatory subunit Rpn12)|interpro:IPR033464|mint:P48556|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5M32|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-180534|uniprotkb:P48556(identity)|entrezgene/locuslink:5714(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:6YpSgdOhNRawROUe3W0t72u6JfA9606 rogid:73qmlkzCwdeHlNzUy7vy7qmIok09606 intact-crc:B2F8556456613C71|rigid:2KWLQz8VuDL+8Sry2JyimsDsRXU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXJ9 uniprotkb:Q96HS1 intact:EBI-1646500|uniprotkb:Q5JWS9|uniprotkb:Q8IYY7|uniprotkb:Q9H466|uniprotkb:Q9NQF8|uniprotkb:Q9UFJ0|uniprotkb:Q9UFP8|uniprotkb:Q9Y2I4|uniprotkb:B2RP59|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978 intact:EBI-713608|uniprotkb:Q96JB0|intact:EBI-2555528|ensembl:ENSP00000438465|uniprotkb:C9IZY7|uniprotkb:A9LN06 psi-mi:asxl1_human(display_long)|uniprotkb:ASXL1(gene name)|psi-mi:ASXL1(display_short)|uniprotkb:KIAA0978(gene name synonym)|uniprotkb:Additional sex combs-like protein 1(gene name synonym) psi-mi:pgam5_human(display_long)|uniprotkb:Bcl-XL-binding protein v68(gene name synonym)|uniprotkb:PGAM5(gene name)|psi-mi:PGAM5(display_short)|uniprotkb:Phosphoglycerate mutase family member 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830826|imex:IM-21659-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056153.2|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978|dip:DIP-46910N|ensembl:ENSG00000171456(gene)|ensembl:ENST00000375687(transcript)|ensembl:ENST00000613218(transcript)|ensembl:ENST00000620121(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035359"(negative regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0035564"(regulation of kidney size)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048538"(thymus development)|go:"GO:0048539"(bone marrow development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060430"(lung saccule development)|go:"GO:0072015"(glomerular visceral epithelial cell development)|interpro:IPR007759(DNA-directed RNA polymerase delta subunit)|interpro:IPR024811|interpro:IPR024815|interpro:IPR026905|interpro:IPR028020|interpro:IPR044867|reactome:R-HSA-5689603|go:"GO:0048386"(positive regulation of retinoic acid receptor signaling pathway)|uniprotkb:Q8IXJ9(identity)|ddbj/embl/genbank:BC064984(identity)|entrezgene/locuslink:171023(identity) refseq:NP_001164014.1|refseq:NP_612642.2|ensembl:ENSG00000247077(gene)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016791"(phosphatase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070266"(necroptotic process)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR029033|mint:Q96HS1|rcsb pdb:3MXO|rcsb pdb:3O0T|rcsb pdb:5MUF|rcsb pdb:6CNI|rcsb pdb:6CNL|reactome:R-HSA-8934903|ensembl:ENST00000498926(transcript)|dip:DIP-50735N|uniprotkb:Q96HS1(identity)|entrezgene/locuslink:192111(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:6YpSgdOhNRawROUe3W0t72u6JfA9606 rogid:prE0I+tNIEjN9Y1NBZbh51DY2+Q9606 intact-crc:B2F8556456613C71|rigid:2KWLQz8VuDL+8Sry2JyimsDsRXU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q76L83 uniprotkb:Q92560 intact:EBI-1058437|uniprotkb:Q76L81|uniprotkb:Q9C0H8|uniprotkb:Q9NV67|uniprotkb:Q53TC9|uniprotkb:Q5H9U4|uniprotkb:Q86XM1|intact:EBI-2558098|intact:EBI-2509978|ensembl:ENSP00000391447 intact:EBI-1791447|uniprotkb:Q6LEM0|uniprotkb:Q7Z5E8|uniprotkb:A8K993|intact:EBI-2558090|ensembl:ENSP00000417132 psi-mi:asxl2_human(display_long)|uniprotkb:ASXL2(gene name)|psi-mi:ASXL2(display_short)|uniprotkb:ASXH2(gene name synonym)|uniprotkb:KIAA1685(gene name synonym)|uniprotkb:Additional sex combs-like protein 2(gene name synonym) psi-mi:bap1_human(display_long)|uniprotkb:BAP1(gene name)|psi-mi:BAP1(display_short)|uniprotkb:KIAA0272(gene name synonym)|uniprotkb:hucep-6(orf name)|uniprotkb:BRCA1-associated protein 1(gene name synonym)|uniprotkb:Cerebral protein 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830903|imex:IM-21659-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060733.4|ensembl:ENSG00000143970(gene)|ensembl:ENST00000435504(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0035360"(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR007759(DNA-directed RNA polymerase delta subunit)|interpro:IPR024811|interpro:IPR024817|interpro:IPR026905|interpro:IPR028020|interpro:IPR044867|reactome:R-HSA-5689603|uniprotkb:Q76L83(identity)|ddbj/embl/genbank:BC042999(identity)|entrezgene/locuslink:55252(identity) dip:DIP-47004N|refseq:NP_004647.1|ensembl:ENSG00000163930(gene)|ensembl:ENST00000460680(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003682"(chromatin binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061519"(macrophage homeostasis)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q92560|reactome:R-HSA-5689603|reactome:R-HSA-5693565|uniprotkb:Q92560(identity)|entrezgene/locuslink:8314(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:O3e0oxBNha1iPYIYsUBSLGP0GPQ9606 rogid:GMWdT1u5HUl29N+YgC/bCKTbxm49606 intact-crc:23FD18E64517A80E|rigid:golOTevQ14k5Pn957l55Is86x1k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q76L83 uniprotkb:Q01167 intact:EBI-1058437|uniprotkb:Q76L81|uniprotkb:Q9C0H8|uniprotkb:Q9NV67|uniprotkb:Q53TC9|uniprotkb:Q5H9U4|uniprotkb:Q86XM1|intact:EBI-2558098|intact:EBI-2509978|ensembl:ENSP00000391447 intact:EBI-2509991|intact:EBI-28976610|ensembl:ENSP00000335677|uniprotkb:Q13624|uniprotkb:Q13623|uniprotkb:A6NEP5|uniprotkb:Q13622 psi-mi:asxl2_human(display_long)|uniprotkb:ASXL2(gene name)|psi-mi:ASXL2(display_short)|uniprotkb:ASXH2(gene name synonym)|uniprotkb:KIAA1685(gene name synonym)|uniprotkb:Additional sex combs-like protein 2(gene name synonym) psi-mi:foxk2_human(display_long)|uniprotkb:G/T-mismatch specific binding protein(gene name synonym)|uniprotkb:FOXK2(gene name)|psi-mi:FOXK2(display_short)|uniprotkb:ILF(gene name synonym)|uniprotkb:ILF1(gene name synonym)|uniprotkb:Interleukin enhancer-binding factor 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830903|imex:IM-21659-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060733.4|ensembl:ENSG00000143970(gene)|ensembl:ENST00000435504(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0035360"(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR007759(DNA-directed RNA polymerase delta subunit)|interpro:IPR024811|interpro:IPR024817|interpro:IPR026905|interpro:IPR028020|interpro:IPR044867|reactome:R-HSA-5689603|uniprotkb:Q76L83(identity)|ddbj/embl/genbank:BC042999(identity)|entrezgene/locuslink:55252(identity) ensembl:ENSG00000141568(gene)|ensembl:ENST00000335255(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0042594"(response to starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR018122|go:"GO:0061621"(canonical glycolysis)|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|mint:Q01167|rcsb pdb:1JXS|rcsb pdb:2C6Y|reactome:R-HSA-5689603|ensembl:ENSP00000335677|ensembl:ENST00000473637|ensembl:ENSP00000436108|refseq:NP_004505.2|uniprotkb:Q01167(identity)|entrezgene/locuslink:3607(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:O3e0oxBNha1iPYIYsUBSLGP0GPQ9606 rogid:mGYtlnM3enVAuU82j5hQ0sui3F49606 intact-crc:23FD18E64517A80E|rigid:golOTevQ14k5Pn957l55Is86x1k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q76L83 uniprotkb:P51610 intact:EBI-1058437|uniprotkb:Q76L81|uniprotkb:Q9C0H8|uniprotkb:Q9NV67|uniprotkb:Q53TC9|uniprotkb:Q5H9U4|uniprotkb:Q86XM1|intact:EBI-2558098|intact:EBI-2509978|ensembl:ENSP00000391447 intact:EBI-396176|intact:EBI-2832627|uniprotkb:Q6P4G5|intact:EBI-12037257|intact:EBI-14324845|ensembl:ENSP00000309555|intact:EBI-12980473 psi-mi:asxl2_human(display_long)|uniprotkb:ASXL2(gene name)|psi-mi:ASXL2(display_short)|uniprotkb:ASXH2(gene name synonym)|uniprotkb:KIAA1685(gene name synonym)|uniprotkb:Additional sex combs-like protein 2(gene name synonym) psi-mi:hcfc1_human(display_long)|uniprotkb:HCFC1(gene name)|psi-mi:HCFC1(display_short)|uniprotkb:HCF1(gene name synonym)|uniprotkb:C1 factor(gene name synonym)|uniprotkb:VP16 accessory protein(gene name synonym)|uniprotkb:VCAF(gene name synonym)|uniprotkb:CFF(gene name synonym)|uniprotkb:HFC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830903|imex:IM-21659-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060733.4|ensembl:ENSG00000143970(gene)|ensembl:ENST00000435504(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0035360"(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR007759(DNA-directed RNA polymerase delta subunit)|interpro:IPR024811|interpro:IPR024817|interpro:IPR026905|interpro:IPR028020|interpro:IPR044867|reactome:R-HSA-5689603|uniprotkb:Q76L83(identity)|ddbj/embl/genbank:BC042999(identity)|entrezgene/locuslink:55252(identity) refseq:NP_005325.2|refseq:XP_006724879.1|rcsb pdb:6MA1|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|reactome:R-HSA-2151201|reactome:R-HSA-3214847|reactome:R-HSA-5689603|ensembl:ENSG00000172534(gene)|ensembl:ENST00000310441(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019046"(release from viral latency)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR036116|interpro:IPR037854|interpro:IPR043536|mint:P51610|rcsb pdb:4GO6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:5LWV|dip:DIP-32955N|uniprotkb:P51610(identity)|entrezgene/locuslink:3054(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:O3e0oxBNha1iPYIYsUBSLGP0GPQ9606 rogid:RzsCRe9l6md3DI87H4ZgdR9oBMI9606 intact-crc:23FD18E64517A80E|rigid:golOTevQ14k5Pn957l55Is86x1k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q76L83 uniprotkb:Q8NB78 intact:EBI-1058437|uniprotkb:Q76L81|uniprotkb:Q9C0H8|uniprotkb:Q9NV67|uniprotkb:Q53TC9|uniprotkb:Q5H9U4|uniprotkb:Q86XM1|intact:EBI-2558098|intact:EBI-2509978|ensembl:ENSP00000391447 intact:EBI-2509999|ensembl:ENSP00000499208|uniprotkb:Q6AI15|uniprotkb:Q6ZUU4|uniprotkb:Q96EL7|uniprotkb:Q5TGV3|uniprotkb:Q8N258|uniprotkb:A2A2C5|uniprotkb:A2A2C6 psi-mi:asxl2_human(display_long)|uniprotkb:ASXL2(gene name)|psi-mi:ASXL2(display_short)|uniprotkb:ASXH2(gene name synonym)|uniprotkb:KIAA1685(gene name synonym)|uniprotkb:Additional sex combs-like protein 2(gene name synonym) psi-mi:kdm1b_human(display_long)|uniprotkb:KDM1B(gene name)|psi-mi:KDM1B(display_short)|uniprotkb:C6orf193(gene name synonym)|uniprotkb:AOF1(gene name synonym)|uniprotkb:LSD2(gene name synonym)|uniprotkb:Lysine-specific histone demethylase 2(gene name synonym)|uniprotkb:Flavin-containing amine oxidase domain-containing protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830903|imex:IM-21659-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060733.4|ensembl:ENSG00000143970(gene)|ensembl:ENST00000435504(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0035360"(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR007759(DNA-directed RNA polymerase delta subunit)|interpro:IPR024811|interpro:IPR024817|interpro:IPR026905|interpro:IPR028020|interpro:IPR044867|reactome:R-HSA-5689603|uniprotkb:Q76L83(identity)|ddbj/embl/genbank:BC042999(identity)|entrezgene/locuslink:55252(identity) ensembl:ENSG00000165097(gene)|ensembl:ENST00000650836(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000786"(nucleosome)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034649"("obsolete histone demethylase activity (H3-monomethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042393"(histone binding)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0071949"(FAD binding)|interpro:IPR002937(Amine oxidase)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR011124(Zinc finger, CW-type)|interpro:IPR036188|interpro:IPR036388|rcsb pdb:4FWE|rcsb pdb:4FWF|rcsb pdb:4FWJ|rcsb pdb:4GU0|rcsb pdb:4GU1|rcsb pdb:4GUR|rcsb pdb:4GUS|rcsb pdb:4GUT|rcsb pdb:4GUU|rcsb pdb:4HSU|rcsb pdb:6R1U|rcsb pdb:6R25|reactome:R-HSA-3214842|reactome:R-HSA-5689603|reactome:R-HSA-9029569|refseq:NP_694587.3|refseq:XP_005248983.1|uniprotkb:Q8NB78(identity)|entrezgene/locuslink:221656(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:O3e0oxBNha1iPYIYsUBSLGP0GPQ9606 rogid:37lP46UxrdbQmFoKabg6UdpVETg9606 intact-crc:23FD18E64517A80E|rigid:golOTevQ14k5Pn957l55Is86x1k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q76L83 uniprotkb:Q96DN6 intact:EBI-1058437|uniprotkb:Q76L81|uniprotkb:Q9C0H8|uniprotkb:Q9NV67|uniprotkb:Q53TC9|uniprotkb:Q5H9U4|uniprotkb:Q86XM1|intact:EBI-2558098|intact:EBI-2509978|ensembl:ENSP00000391447 intact:EBI-719591|uniprotkb:Q8N3M0|uniprotkb:Q8NA81|uniprotkb:Q96Q00|ensembl:ENSP00000347896 psi-mi:asxl2_human(display_long)|uniprotkb:ASXL2(gene name)|psi-mi:ASXL2(display_short)|uniprotkb:ASXH2(gene name synonym)|uniprotkb:KIAA1685(gene name synonym)|uniprotkb:Additional sex combs-like protein 2(gene name synonym) psi-mi:mbd6_human(display_long)|uniprotkb:Methyl-CpG-binding protein MBD6(gene name synonym)|uniprotkb:MBD6(gene name)|psi-mi:MBD6(display_short)|uniprotkb:KIAA1887(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830903|imex:IM-21659-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060733.4|ensembl:ENSG00000143970(gene)|ensembl:ENST00000435504(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0035360"(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR007759(DNA-directed RNA polymerase delta subunit)|interpro:IPR024811|interpro:IPR024817|interpro:IPR026905|interpro:IPR028020|interpro:IPR044867|reactome:R-HSA-5689603|uniprotkb:Q76L83(identity)|ddbj/embl/genbank:BC042999(identity)|entrezgene/locuslink:55252(identity) refseq:NP_443129.3|ensembl:ENSG00000166987(gene)|ensembl:ENST00000355673(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0010369"(chromocenter)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR037385|reactome:R-HSA-5689603|uniprotkb:Q96DN6(identity)|entrezgene/locuslink:114785(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:O3e0oxBNha1iPYIYsUBSLGP0GPQ9606 rogid:b/lOJGEiC6RxM4s3rq8nXw6zmjE9606 intact-crc:23FD18E64517A80E|rigid:golOTevQ14k5Pn957l55Is86x1k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q76L83 uniprotkb:P55000 intact:EBI-1058437|uniprotkb:Q76L81|uniprotkb:Q9C0H8|uniprotkb:Q9NV67|uniprotkb:Q53TC9|uniprotkb:Q5H9U4|uniprotkb:Q86XM1|intact:EBI-2558098|intact:EBI-2509978|ensembl:ENSP00000391447 intact:EBI-8830896|uniprotkb:Q6PUA6|uniprotkb:Q53YJ6|uniprotkb:Q92483|ensembl:ENSP00000246515 psi-mi:asxl2_human(display_long)|uniprotkb:ASXL2(gene name)|psi-mi:ASXL2(display_short)|uniprotkb:ASXH2(gene name synonym)|uniprotkb:KIAA1685(gene name synonym)|uniprotkb:Additional sex combs-like protein 2(gene name synonym) psi-mi:slur1_human(display_long)|uniprotkb:ARS(gene name synonym)|uniprotkb:ARS component B(gene name synonym)|uniprotkb:"ARS(component B)-81/S"(gene name synonym)|uniprotkb:Anti-neoplastic urinary protein(gene name synonym)|uniprotkb:SLURP1(gene name)|psi-mi:SLURP1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830903|imex:IM-21659-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060733.4|ensembl:ENSG00000143970(gene)|ensembl:ENST00000435504(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0035360"(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR007759(DNA-directed RNA polymerase delta subunit)|interpro:IPR024811|interpro:IPR024817|interpro:IPR026905|interpro:IPR028020|interpro:IPR044867|reactome:R-HSA-5689603|uniprotkb:Q76L83(identity)|ddbj/embl/genbank:BC042999(identity)|entrezgene/locuslink:55252(identity) refseq:NP_065160.1|ensembl:ENSG00000126233(gene)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007155"(cell adhesion)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030549"(acetylcholine receptor activator activity)|go:"GO:0038195"(urokinase plasminogen activator signaling pathway)|go:"GO:0050884"(neuromuscular process controlling posture)|go:"GO:0070062"(extracellular exosome)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|interpro:IPR027103|rcsb pdb:6ZZE|rcsb pdb:6ZZF|go:"GO:0001775"(cell activation)|ensembl:ENST00000246515(transcript)|uniprotkb:P55000(identity)|entrezgene/locuslink:57152(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:O3e0oxBNha1iPYIYsUBSLGP0GPQ9606 rogid:+h63SfLP+/w0r0UoFvZG6jinDao9606 intact-crc:23FD18E64517A80E|rigid:golOTevQ14k5Pn957l55Is86x1k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q76L83 uniprotkb:Q9BQE3 intact:EBI-1058437|uniprotkb:Q76L81|uniprotkb:Q9C0H8|uniprotkb:Q9NV67|uniprotkb:Q53TC9|uniprotkb:Q5H9U4|uniprotkb:Q86XM1|intact:EBI-2558098|intact:EBI-2509978|ensembl:ENSP00000391447 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:asxl2_human(display_long)|uniprotkb:ASXL2(gene name)|psi-mi:ASXL2(display_short)|uniprotkb:ASXH2(gene name synonym)|uniprotkb:KIAA1685(gene name synonym)|uniprotkb:Additional sex combs-like protein 2(gene name synonym) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830903|imex:IM-21659-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060733.4|ensembl:ENSG00000143970(gene)|ensembl:ENST00000435504(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0035360"(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR007759(DNA-directed RNA polymerase delta subunit)|interpro:IPR024811|interpro:IPR024817|interpro:IPR026905|interpro:IPR028020|interpro:IPR044867|reactome:R-HSA-5689603|uniprotkb:Q76L83(identity)|ddbj/embl/genbank:BC042999(identity)|entrezgene/locuslink:55252(identity) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1|uniprotkb:Q9BQE3(identity)|entrezgene/locuslink:84790(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:O3e0oxBNha1iPYIYsUBSLGP0GPQ9606 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:23FD18E64517A80E|rigid:golOTevQ14k5Pn957l55Is86x1k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q76L83 uniprotkb:O15294 intact:EBI-1058437|uniprotkb:Q76L81|uniprotkb:Q9C0H8|uniprotkb:Q9NV67|uniprotkb:Q53TC9|uniprotkb:Q5H9U4|uniprotkb:Q86XM1|intact:EBI-2558098|intact:EBI-2509978|ensembl:ENSP00000391447 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 psi-mi:asxl2_human(display_long)|uniprotkb:ASXL2(gene name)|psi-mi:ASXL2(display_short)|uniprotkb:ASXH2(gene name synonym)|uniprotkb:KIAA1685(gene name synonym)|uniprotkb:Additional sex combs-like protein 2(gene name synonym) psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830903|imex:IM-21659-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060733.4|ensembl:ENSG00000143970(gene)|ensembl:ENST00000435504(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0035360"(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR007759(DNA-directed RNA polymerase delta subunit)|interpro:IPR024811|interpro:IPR024817|interpro:IPR026905|interpro:IPR028020|interpro:IPR044867|reactome:R-HSA-5689603|uniprotkb:Q76L83(identity)|ddbj/embl/genbank:BC042999(identity)|entrezgene/locuslink:55252(identity) refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N|uniprotkb:O15294(identity)|entrezgene/locuslink:8473(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:O3e0oxBNha1iPYIYsUBSLGP0GPQ9606 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 intact-crc:23FD18E64517A80E|rigid:golOTevQ14k5Pn957l55Is86x1k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q76L83 uniprotkb:P85037 intact:EBI-1058437|uniprotkb:Q76L81|uniprotkb:Q9C0H8|uniprotkb:Q9NV67|uniprotkb:Q53TC9|uniprotkb:Q5H9U4|uniprotkb:Q86XM1|intact:EBI-2558098|intact:EBI-2509978|ensembl:ENSP00000391447 intact:EBI-2509974|ensembl:ENSP00000328720 psi-mi:asxl2_human(display_long)|uniprotkb:ASXL2(gene name)|psi-mi:ASXL2(display_short)|uniprotkb:ASXH2(gene name synonym)|uniprotkb:KIAA1685(gene name synonym)|uniprotkb:Additional sex combs-like protein 2(gene name synonym) psi-mi:foxk1_human(display_long)|uniprotkb:FOXK1(gene name)|psi-mi:FOXK1(display_short)|uniprotkb:MNF(gene name synonym)|uniprotkb:Myocyte nuclear factor(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830903|imex:IM-21659-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060733.4|ensembl:ENSG00000143970(gene)|ensembl:ENST00000435504(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0035360"(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR007759(DNA-directed RNA polymerase delta subunit)|interpro:IPR024811|interpro:IPR024817|interpro:IPR026905|interpro:IPR028020|interpro:IPR044867|reactome:R-HSA-5689603|uniprotkb:Q76L83(identity)|ddbj/embl/genbank:BC042999(identity)|entrezgene/locuslink:55252(identity) ensembl:ENSG00000164916(gene)|ensembl:ENST00000328914(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0042594"(response to starvation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5689603|refseq:XP_011513493.1|refseq:NP_001032242.1|uniprotkb:P85037(identity)|entrezgene/locuslink:221937(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:O3e0oxBNha1iPYIYsUBSLGP0GPQ9606 rogid:ngoE3oNlIDGkTf1ZMYG4OQ6lvE09606 intact-crc:23FD18E64517A80E|rigid:golOTevQ14k5Pn957l55Is86x1k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92560 uniprotkb:Q01167 intact:EBI-1791447|uniprotkb:Q6LEM0|uniprotkb:Q7Z5E8|uniprotkb:A8K993|intact:EBI-2558090|ensembl:ENSP00000417132 intact:EBI-2509991|intact:EBI-28976610|ensembl:ENSP00000335677|uniprotkb:Q13624|uniprotkb:Q13623|uniprotkb:A6NEP5|uniprotkb:Q13622 psi-mi:bap1_human(display_long)|uniprotkb:BAP1(gene name)|psi-mi:BAP1(display_short)|uniprotkb:KIAA0272(gene name synonym)|uniprotkb:hucep-6(orf name)|uniprotkb:BRCA1-associated protein 1(gene name synonym)|uniprotkb:Cerebral protein 6(gene name synonym) psi-mi:foxk2_human(display_long)|uniprotkb:G/T-mismatch specific binding protein(gene name synonym)|uniprotkb:FOXK2(gene name)|psi-mi:FOXK2(display_short)|uniprotkb:ILF(gene name synonym)|uniprotkb:ILF1(gene name synonym)|uniprotkb:Interleukin enhancer-binding factor 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830949|imex:IM-21659-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-47004N|refseq:NP_004647.1|ensembl:ENSG00000163930(gene)|ensembl:ENST00000460680(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003682"(chromatin binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061519"(macrophage homeostasis)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q92560|reactome:R-HSA-5689603|reactome:R-HSA-5693565|uniprotkb:Q92560(identity)|ddbj/embl/genbank:BC001596(identity)|entrezgene/locuslink:8314(identity) ensembl:ENSG00000141568(gene)|ensembl:ENST00000335255(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0042594"(response to starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR018122|go:"GO:0061621"(canonical glycolysis)|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|mint:Q01167|rcsb pdb:1JXS|rcsb pdb:2C6Y|reactome:R-HSA-5689603|ensembl:ENSP00000335677|ensembl:ENST00000473637|ensembl:ENSP00000436108|refseq:NP_004505.2|uniprotkb:Q01167(identity)|entrezgene/locuslink:3607(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:GMWdT1u5HUl29N+YgC/bCKTbxm49606 rogid:mGYtlnM3enVAuU82j5hQ0sui3F49606 intact-crc:D8F19ED7A1FEFCE8|rigid:Sr6C8aW8XMCew5JCU1mAP1hX2ds false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92560 uniprotkb:P62333 intact:EBI-1791447|uniprotkb:Q6LEM0|uniprotkb:Q7Z5E8|uniprotkb:A8K993|intact:EBI-2558090|ensembl:ENSP00000417132 intact:EBI-357669|uniprotkb:Q92524|uniprotkb:P49719|uniprotkb:Q6IBU3|uniprotkb:B2R975|ensembl:ENSP00000401802 psi-mi:bap1_human(display_long)|uniprotkb:BAP1(gene name)|psi-mi:BAP1(display_short)|uniprotkb:KIAA0272(gene name synonym)|uniprotkb:hucep-6(orf name)|uniprotkb:BRCA1-associated protein 1(gene name synonym)|uniprotkb:Cerebral protein 6(gene name synonym) psi-mi:prs10_human(display_long)|uniprotkb:PSMC6(gene name)|psi-mi:PSMC6(display_short)|uniprotkb:SUG2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 6(gene name synonym)|uniprotkb:Proteasome subunit p42(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830949|imex:IM-21659-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-47004N|refseq:NP_004647.1|ensembl:ENSG00000163930(gene)|ensembl:ENST00000460680(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003682"(chromatin binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061519"(macrophage homeostasis)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q92560|reactome:R-HSA-5689603|reactome:R-HSA-5693565|uniprotkb:Q92560(identity)|ddbj/embl/genbank:BC001596(identity)|entrezgene/locuslink:8314(identity) refseq:NP_002797.3|ensembl:ENST00000445930(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000100519(gene)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR032501|interpro:IPR035263|interpro:IPR041569|mint:P62333|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-75815|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-174184|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|dip:DIP-38150N|uniprotkb:P62333(identity)|entrezgene/locuslink:5706(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:GMWdT1u5HUl29N+YgC/bCKTbxm49606 rogid:QE8jzSEp1bpzhOi/oAAnV18QK249606 intact-crc:D8F19ED7A1FEFCE8|rigid:Sr6C8aW8XMCew5JCU1mAP1hX2ds false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92560 uniprotkb:O15294 intact:EBI-1791447|uniprotkb:Q6LEM0|uniprotkb:Q7Z5E8|uniprotkb:A8K993|intact:EBI-2558090|ensembl:ENSP00000417132 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 psi-mi:bap1_human(display_long)|uniprotkb:BAP1(gene name)|psi-mi:BAP1(display_short)|uniprotkb:KIAA0272(gene name synonym)|uniprotkb:hucep-6(orf name)|uniprotkb:BRCA1-associated protein 1(gene name synonym)|uniprotkb:Cerebral protein 6(gene name synonym) psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830949|imex:IM-21659-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-47004N|refseq:NP_004647.1|ensembl:ENSG00000163930(gene)|ensembl:ENST00000460680(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003682"(chromatin binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061519"(macrophage homeostasis)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q92560|reactome:R-HSA-5689603|reactome:R-HSA-5693565|uniprotkb:Q92560(identity)|ddbj/embl/genbank:BC001596(identity)|entrezgene/locuslink:8314(identity) refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N|uniprotkb:O15294(identity)|entrezgene/locuslink:8473(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:GMWdT1u5HUl29N+YgC/bCKTbxm49606 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 intact-crc:D8F19ED7A1FEFCE8|rigid:Sr6C8aW8XMCew5JCU1mAP1hX2ds false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92560 uniprotkb:O00231 intact:EBI-1791447|uniprotkb:Q6LEM0|uniprotkb:Q7Z5E8|uniprotkb:A8K993|intact:EBI-2558090|ensembl:ENSP00000417132 intact:EBI-357816|uniprotkb:O00495|uniprotkb:A8K3I7|uniprotkb:E1P663|uniprotkb:Q53FT5|ensembl:ENSP00000261712|ensembl:ENSP00000393185|ensembl:ENSP00000497128 psi-mi:bap1_human(display_long)|uniprotkb:BAP1(gene name)|psi-mi:BAP1(display_short)|uniprotkb:KIAA0272(gene name synonym)|uniprotkb:hucep-6(orf name)|uniprotkb:BRCA1-associated protein 1(gene name synonym)|uniprotkb:Cerebral protein 6(gene name synonym) psi-mi:psd11_human(display_long)|uniprotkb:PSMD11(gene name)|psi-mi:PSMD11(display_short)|uniprotkb:26S proteasome regulatory subunit S9(gene name synonym)|uniprotkb:26S proteasome regulatory subunit p44.5(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830949|imex:IM-21659-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-47004N|refseq:NP_004647.1|ensembl:ENSG00000163930(gene)|ensembl:ENST00000460680(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003682"(chromatin binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061519"(macrophage homeostasis)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q92560|reactome:R-HSA-5689603|reactome:R-HSA-5693565|uniprotkb:Q92560(identity)|ddbj/embl/genbank:BC001596(identity)|entrezgene/locuslink:8314(identity) refseq:NP_002806.2|refseq:NP_001257411.1|ensembl:ENSG00000108671(gene)|ensembl:ENST00000261712(transcript)|ensembl:ENST00000457654(transcript)|ensembl:ENST00000649012(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048863"(stem cell differentiation)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR035295|interpro:IPR036390|interpro:IPR040773|interpro:IPR040780|mint:O00231|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5M32|rcsb pdb:5LN3|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|uniprotkb:O00231(identity)|entrezgene/locuslink:5717(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:GMWdT1u5HUl29N+YgC/bCKTbxm49606 rogid:BgQKXK7gMMihacRCI+g/pBnRN309606 intact-crc:D8F19ED7A1FEFCE8|rigid:Sr6C8aW8XMCew5JCU1mAP1hX2ds false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92560 uniprotkb:Q96DN6 intact:EBI-1791447|uniprotkb:Q6LEM0|uniprotkb:Q7Z5E8|uniprotkb:A8K993|intact:EBI-2558090|ensembl:ENSP00000417132 intact:EBI-719591|uniprotkb:Q8N3M0|uniprotkb:Q8NA81|uniprotkb:Q96Q00|ensembl:ENSP00000347896 psi-mi:bap1_human(display_long)|uniprotkb:BAP1(gene name)|psi-mi:BAP1(display_short)|uniprotkb:KIAA0272(gene name synonym)|uniprotkb:hucep-6(orf name)|uniprotkb:BRCA1-associated protein 1(gene name synonym)|uniprotkb:Cerebral protein 6(gene name synonym) psi-mi:mbd6_human(display_long)|uniprotkb:Methyl-CpG-binding protein MBD6(gene name synonym)|uniprotkb:MBD6(gene name)|psi-mi:MBD6(display_short)|uniprotkb:KIAA1887(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830949|imex:IM-21659-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-47004N|refseq:NP_004647.1|ensembl:ENSG00000163930(gene)|ensembl:ENST00000460680(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003682"(chromatin binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061519"(macrophage homeostasis)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q92560|reactome:R-HSA-5689603|reactome:R-HSA-5693565|uniprotkb:Q92560(identity)|ddbj/embl/genbank:BC001596(identity)|entrezgene/locuslink:8314(identity) refseq:NP_443129.3|ensembl:ENSG00000166987(gene)|ensembl:ENST00000355673(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0010369"(chromocenter)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR037385|reactome:R-HSA-5689603|uniprotkb:Q96DN6(identity)|entrezgene/locuslink:114785(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:GMWdT1u5HUl29N+YgC/bCKTbxm49606 rogid:b/lOJGEiC6RxM4s3rq8nXw6zmjE9606 intact-crc:D8F19ED7A1FEFCE8|rigid:Sr6C8aW8XMCew5JCU1mAP1hX2ds false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92560 uniprotkb:P35998 intact:EBI-1791447|uniprotkb:Q6LEM0|uniprotkb:Q7Z5E8|uniprotkb:A8K993|intact:EBI-2558090|ensembl:ENSP00000417132 intact:EBI-359710|uniprotkb:B7Z5E2|uniprotkb:A4D0Q1|uniprotkb:Q3LIA5|uniprotkb:Q9UDI3|ensembl:ENSP00000292644|ensembl:ENSP00000391211|ensembl:ENSP00000502939|ensembl:ENSP00000503179|ensembl:ENSP00000504608 psi-mi:bap1_human(display_long)|uniprotkb:BAP1(gene name)|psi-mi:BAP1(display_short)|uniprotkb:KIAA0272(gene name synonym)|uniprotkb:hucep-6(orf name)|uniprotkb:BRCA1-associated protein 1(gene name synonym)|uniprotkb:Cerebral protein 6(gene name synonym) psi-mi:prs7_human(display_long)|uniprotkb:PSMC2(gene name)|psi-mi:PSMC2(display_short)|uniprotkb:MSS1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 2(gene name synonym)|uniprotkb:Protein MSS1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830949|imex:IM-21659-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-47004N|refseq:NP_004647.1|ensembl:ENSG00000163930(gene)|ensembl:ENST00000460680(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003682"(chromatin binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061519"(macrophage homeostasis)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q92560|reactome:R-HSA-5689603|reactome:R-HSA-5693565|uniprotkb:Q92560(identity)|ddbj/embl/genbank:BC001596(identity)|entrezgene/locuslink:8314(identity) refseq:NP_001191382.1|refseq:NP_002794.1|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR035245|interpro:IPR041569|mint:P35998|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|interpro:IPR003960(AAA ATPase, conserved site)|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|ensembl:ENSG00000161057(gene)|ensembl:ENST00000292644(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|ensembl:ENST00000435765(transcript)|ensembl:ENST00000678493(transcript)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|ensembl:ENST00000679205(transcript)|ensembl:ENST00000679341(transcript)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0043197"(dendritic spine)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5VHQ|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5610780|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|dip:DIP-27554N|uniprotkb:P35998(identity)|entrezgene/locuslink:5701(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:GMWdT1u5HUl29N+YgC/bCKTbxm49606 rogid:ahQfjPKywP5DWNq3FB5XCjuqkJ09606 intact-crc:D8F19ED7A1FEFCE8|rigid:Sr6C8aW8XMCew5JCU1mAP1hX2ds false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92560 uniprotkb:P43686 intact:EBI-1791447|uniprotkb:Q6LEM0|uniprotkb:Q7Z5E8|uniprotkb:A8K993|intact:EBI-2558090|ensembl:ENSP00000417132 intact:EBI-743997|uniprotkb:Q96FV5|uniprotkb:Q9UBM3|uniprotkb:Q9UEX3|ensembl:ENSP00000157812|ensembl:ENSP00000487367 psi-mi:bap1_human(display_long)|uniprotkb:BAP1(gene name)|psi-mi:BAP1(display_short)|uniprotkb:KIAA0272(gene name synonym)|uniprotkb:hucep-6(orf name)|uniprotkb:BRCA1-associated protein 1(gene name synonym)|uniprotkb:Cerebral protein 6(gene name synonym) psi-mi:prs6b_human(display_long)|uniprotkb:Proteasome 26S subunit ATPase 4(gene name synonym)|uniprotkb:MB67-interacting protein(gene name synonym)|uniprotkb:PSMC4(gene name)|psi-mi:PSMC4(display_short)|uniprotkb:TBP7(gene name synonym)|uniprotkb:MIP224(gene name synonym)|uniprotkb:Tat-binding protein 7(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830949|imex:IM-21659-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-47004N|refseq:NP_004647.1|ensembl:ENSG00000163930(gene)|ensembl:ENST00000460680(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003682"(chromatin binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061519"(macrophage homeostasis)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q92560|reactome:R-HSA-5689603|reactome:R-HSA-5693565|uniprotkb:Q92560(identity)|ddbj/embl/genbank:BC001596(identity)|entrezgene/locuslink:8314(identity) refseq:NP_006494.1|refseq:NP_694546.1|dip:DIP-29274N|ensembl:ENSG00000013275(gene)|ensembl:ENSG00000281221(gene)|ensembl:ENST00000157812(transcript)|ensembl:ENST00000629691(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045202"(synapse)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035256|interpro:IPR041569|mint:P43686|rcsb pdb:2DVW|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-69601|uniprotkb:P43686(identity)|entrezgene/locuslink:5704(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:GMWdT1u5HUl29N+YgC/bCKTbxm49606 rogid:ZwHUFX8vJa8IPZi000dHiFtUtlM9606 intact-crc:D8F19ED7A1FEFCE8|rigid:Sr6C8aW8XMCew5JCU1mAP1hX2ds false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92560 uniprotkb:Q9BQE3 intact:EBI-1791447|uniprotkb:Q6LEM0|uniprotkb:Q7Z5E8|uniprotkb:A8K993|intact:EBI-2558090|ensembl:ENSP00000417132 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:bap1_human(display_long)|uniprotkb:BAP1(gene name)|psi-mi:BAP1(display_short)|uniprotkb:KIAA0272(gene name synonym)|uniprotkb:hucep-6(orf name)|uniprotkb:BRCA1-associated protein 1(gene name synonym)|uniprotkb:Cerebral protein 6(gene name synonym) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830949|imex:IM-21659-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-47004N|refseq:NP_004647.1|ensembl:ENSG00000163930(gene)|ensembl:ENST00000460680(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003682"(chromatin binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061519"(macrophage homeostasis)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q92560|reactome:R-HSA-5689603|reactome:R-HSA-5693565|uniprotkb:Q92560(identity)|ddbj/embl/genbank:BC001596(identity)|entrezgene/locuslink:8314(identity) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1|uniprotkb:Q9BQE3(identity)|entrezgene/locuslink:84790(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:GMWdT1u5HUl29N+YgC/bCKTbxm49606 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:D8F19ED7A1FEFCE8|rigid:Sr6C8aW8XMCew5JCU1mAP1hX2ds false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92560 uniprotkb:Q9C0C9 intact:EBI-1791447|uniprotkb:Q6LEM0|uniprotkb:Q7Z5E8|uniprotkb:A8K993|intact:EBI-2558090|ensembl:ENSP00000417132 intact:EBI-2339946|uniprotkb:Q8N425|uniprotkb:Q9H9B2|uniprotkb:Q6PIZ2|uniprotkb:Q9H7E4|uniprotkb:Q8TBN1|uniprotkb:A6NDU5|uniprotkb:Q9BSW1|uniprotkb:Q69YP4|uniprotkb:Q86UA4|uniprotkb:Q9H6E6|ensembl:ENSP00000323687 psi-mi:bap1_human(display_long)|uniprotkb:BAP1(gene name)|psi-mi:BAP1(display_short)|uniprotkb:KIAA0272(gene name synonym)|uniprotkb:hucep-6(orf name)|uniprotkb:BRCA1-associated protein 1(gene name synonym)|uniprotkb:Cerebral protein 6(gene name synonym) psi-mi:ube2o_human(display_long)|uniprotkb:UBE2O(gene name)|psi-mi:UBE2O(display_short)|uniprotkb:KIAA1734(gene name synonym)|uniprotkb:Ubiquitin-protein ligase O(gene name synonym)|uniprotkb:Ubiquitin carrier protein O(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 of 230 kDa(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 O(gene name synonym)|uniprotkb:E2/E3 hybrid ubiquitin-protein ligase UBE2O(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830949|imex:IM-21659-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-47004N|refseq:NP_004647.1|ensembl:ENSG00000163930(gene)|ensembl:ENST00000460680(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003682"(chromatin binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061519"(macrophage homeostasis)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q92560|reactome:R-HSA-5689603|reactome:R-HSA-5693565|uniprotkb:Q92560(identity)|ddbj/embl/genbank:BC001596(identity)|entrezgene/locuslink:8314(identity) refseq:NP_071349.3|ensembl:ENSG00000175931(gene)|ensembl:ENST00000319380(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q9C0C9|reactome:R-HSA-983168|uniprotkb:Q9C0C9(identity)|entrezgene/locuslink:63893(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:GMWdT1u5HUl29N+YgC/bCKTbxm49606 rogid:FftBetvip/qFQAsQxmxRnGy8ctA9606 intact-crc:D8F19ED7A1FEFCE8|rigid:Sr6C8aW8XMCew5JCU1mAP1hX2ds false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92560 uniprotkb:Q96HS1 intact:EBI-1791447|uniprotkb:Q6LEM0|uniprotkb:Q7Z5E8|uniprotkb:A8K993|intact:EBI-2558090|ensembl:ENSP00000417132 intact:EBI-713608|uniprotkb:Q96JB0|intact:EBI-2555528|ensembl:ENSP00000438465|uniprotkb:C9IZY7|uniprotkb:A9LN06 psi-mi:bap1_human(display_long)|uniprotkb:BAP1(gene name)|psi-mi:BAP1(display_short)|uniprotkb:KIAA0272(gene name synonym)|uniprotkb:hucep-6(orf name)|uniprotkb:BRCA1-associated protein 1(gene name synonym)|uniprotkb:Cerebral protein 6(gene name synonym) psi-mi:pgam5_human(display_long)|uniprotkb:Bcl-XL-binding protein v68(gene name synonym)|uniprotkb:PGAM5(gene name)|psi-mi:PGAM5(display_short)|uniprotkb:Phosphoglycerate mutase family member 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830949|imex:IM-21659-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-47004N|refseq:NP_004647.1|ensembl:ENSG00000163930(gene)|ensembl:ENST00000460680(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003682"(chromatin binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061519"(macrophage homeostasis)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q92560|reactome:R-HSA-5689603|reactome:R-HSA-5693565|uniprotkb:Q92560(identity)|ddbj/embl/genbank:BC001596(identity)|entrezgene/locuslink:8314(identity) refseq:NP_001164014.1|refseq:NP_612642.2|ensembl:ENSG00000247077(gene)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016791"(phosphatase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070266"(necroptotic process)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR029033|mint:Q96HS1|rcsb pdb:3MXO|rcsb pdb:3O0T|rcsb pdb:5MUF|rcsb pdb:6CNI|rcsb pdb:6CNL|reactome:R-HSA-8934903|ensembl:ENST00000498926(transcript)|dip:DIP-50735N|uniprotkb:Q96HS1(identity)|entrezgene/locuslink:192111(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:GMWdT1u5HUl29N+YgC/bCKTbxm49606 rogid:prE0I+tNIEjN9Y1NBZbh51DY2+Q9606 intact-crc:D8F19ED7A1FEFCE8|rigid:Sr6C8aW8XMCew5JCU1mAP1hX2ds false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92560 uniprotkb:Q8IXJ9 intact:EBI-1791447|uniprotkb:Q6LEM0|uniprotkb:Q7Z5E8|uniprotkb:A8K993|intact:EBI-2558090|ensembl:ENSP00000417132 intact:EBI-1646500|uniprotkb:Q5JWS9|uniprotkb:Q8IYY7|uniprotkb:Q9H466|uniprotkb:Q9NQF8|uniprotkb:Q9UFJ0|uniprotkb:Q9UFP8|uniprotkb:Q9Y2I4|uniprotkb:B2RP59|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978 psi-mi:bap1_human(display_long)|uniprotkb:BAP1(gene name)|psi-mi:BAP1(display_short)|uniprotkb:KIAA0272(gene name synonym)|uniprotkb:hucep-6(orf name)|uniprotkb:BRCA1-associated protein 1(gene name synonym)|uniprotkb:Cerebral protein 6(gene name synonym) psi-mi:asxl1_human(display_long)|uniprotkb:ASXL1(gene name)|psi-mi:ASXL1(display_short)|uniprotkb:KIAA0978(gene name synonym)|uniprotkb:Additional sex combs-like protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830949|imex:IM-21659-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-47004N|refseq:NP_004647.1|ensembl:ENSG00000163930(gene)|ensembl:ENST00000460680(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003682"(chromatin binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061519"(macrophage homeostasis)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q92560|reactome:R-HSA-5689603|reactome:R-HSA-5693565|uniprotkb:Q92560(identity)|ddbj/embl/genbank:BC001596(identity)|entrezgene/locuslink:8314(identity) refseq:NP_056153.2|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978|dip:DIP-46910N|ensembl:ENSG00000171456(gene)|ensembl:ENST00000375687(transcript)|ensembl:ENST00000613218(transcript)|ensembl:ENST00000620121(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035359"(negative regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0035564"(regulation of kidney size)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048538"(thymus development)|go:"GO:0048539"(bone marrow development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060430"(lung saccule development)|go:"GO:0072015"(glomerular visceral epithelial cell development)|interpro:IPR007759(DNA-directed RNA polymerase delta subunit)|interpro:IPR024811|interpro:IPR024815|interpro:IPR026905|interpro:IPR028020|interpro:IPR044867|reactome:R-HSA-5689603|go:"GO:0048386"(positive regulation of retinoic acid receptor signaling pathway)|uniprotkb:Q8IXJ9(identity)|entrezgene/locuslink:171023(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:GMWdT1u5HUl29N+YgC/bCKTbxm49606 rogid:6YpSgdOhNRawROUe3W0t72u6JfA9606 intact-crc:D8F19ED7A1FEFCE8|rigid:Sr6C8aW8XMCew5JCU1mAP1hX2ds false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92560 uniprotkb:P55036 intact:EBI-1791447|uniprotkb:Q6LEM0|uniprotkb:Q7Z5E8|uniprotkb:A8K993|intact:EBI-2558090|ensembl:ENSP00000417132 intact:EBI-359318|uniprotkb:Q5VWC5|uniprotkb:Q9NS92|uniprotkb:D3DV16|ensembl:ENSP00000357879 psi-mi:bap1_human(display_long)|uniprotkb:BAP1(gene name)|psi-mi:BAP1(display_short)|uniprotkb:KIAA0272(gene name synonym)|uniprotkb:hucep-6(orf name)|uniprotkb:BRCA1-associated protein 1(gene name synonym)|uniprotkb:Cerebral protein 6(gene name synonym) psi-mi:psmd4_human(display_long)|uniprotkb:PSMD4(gene name)|psi-mi:PSMD4(display_short)|uniprotkb:MCB1(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S5A(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN10(gene name synonym)|uniprotkb:Multiubiquitin chain-binding protein(gene name synonym)|uniprotkb:Antisecretory factor 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830949|imex:IM-21659-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-47004N|refseq:NP_004647.1|ensembl:ENSG00000163930(gene)|ensembl:ENST00000460680(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003682"(chromatin binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061519"(macrophage homeostasis)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q92560|reactome:R-HSA-5689603|reactome:R-HSA-5693565|uniprotkb:Q92560(identity)|ddbj/embl/genbank:BC001596(identity)|entrezgene/locuslink:8314(identity) refseq:NP_002801.1|dip:DIP-38189N|ensembl:ENSG00000159352(gene)|ensembl:ENST00000368884(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR036465|mint:P55036|rcsb pdb:1P9C|rcsb pdb:1P9D|rcsb pdb:1UEL|rcsb pdb:1YX4|rcsb pdb:1YX5|rcsb pdb:1YX6|rcsb pdb:2KDE|rcsb pdb:2KDF|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6MUN|rcsb pdb:6U19|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|uniprotkb:P55036(identity)|entrezgene/locuslink:5710(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:GMWdT1u5HUl29N+YgC/bCKTbxm49606 rogid:FTJG3ns3Ag/Y3xP3yEydGxppRcA9606 intact-crc:D8F19ED7A1FEFCE8|rigid:Sr6C8aW8XMCew5JCU1mAP1hX2ds false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92560 uniprotkb:Q76L83 intact:EBI-1791447|uniprotkb:Q6LEM0|uniprotkb:Q7Z5E8|uniprotkb:A8K993|intact:EBI-2558090|ensembl:ENSP00000417132 intact:EBI-1058437|uniprotkb:Q76L81|uniprotkb:Q9C0H8|uniprotkb:Q9NV67|uniprotkb:Q53TC9|uniprotkb:Q5H9U4|uniprotkb:Q86XM1|intact:EBI-2558098|intact:EBI-2509978|ensembl:ENSP00000391447 psi-mi:bap1_human(display_long)|uniprotkb:BAP1(gene name)|psi-mi:BAP1(display_short)|uniprotkb:KIAA0272(gene name synonym)|uniprotkb:hucep-6(orf name)|uniprotkb:BRCA1-associated protein 1(gene name synonym)|uniprotkb:Cerebral protein 6(gene name synonym) psi-mi:asxl2_human(display_long)|uniprotkb:ASXL2(gene name)|psi-mi:ASXL2(display_short)|uniprotkb:ASXH2(gene name synonym)|uniprotkb:KIAA1685(gene name synonym)|uniprotkb:Additional sex combs-like protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830949|imex:IM-21659-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-47004N|refseq:NP_004647.1|ensembl:ENSG00000163930(gene)|ensembl:ENST00000460680(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003682"(chromatin binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061519"(macrophage homeostasis)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q92560|reactome:R-HSA-5689603|reactome:R-HSA-5693565|uniprotkb:Q92560(identity)|ddbj/embl/genbank:BC001596(identity)|entrezgene/locuslink:8314(identity) refseq:NP_060733.4|ensembl:ENSG00000143970(gene)|ensembl:ENST00000435504(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0035360"(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR007759(DNA-directed RNA polymerase delta subunit)|interpro:IPR024811|interpro:IPR024817|interpro:IPR026905|interpro:IPR028020|interpro:IPR044867|reactome:R-HSA-5689603|uniprotkb:Q76L83(identity)|entrezgene/locuslink:55252(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:GMWdT1u5HUl29N+YgC/bCKTbxm49606 rogid:O3e0oxBNha1iPYIYsUBSLGP0GPQ9606 intact-crc:D8F19ED7A1FEFCE8|rigid:Sr6C8aW8XMCew5JCU1mAP1hX2ds false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92560 uniprotkb:Q13200 intact:EBI-1791447|uniprotkb:Q6LEM0|uniprotkb:Q7Z5E8|uniprotkb:A8K993|intact:EBI-2558090|ensembl:ENSP00000417132 intact:EBI-357648|uniprotkb:B4DX07|uniprotkb:B4DXY1|uniprotkb:E7EW34|uniprotkb:E9PCS3|uniprotkb:Q12932|uniprotkb:Q15321|uniprotkb:Q96I12|ensembl:ENSP00000310129|uniprotkb:Q53XQ4 psi-mi:bap1_human(display_long)|uniprotkb:BAP1(gene name)|psi-mi:BAP1(display_short)|uniprotkb:KIAA0272(gene name synonym)|uniprotkb:hucep-6(orf name)|uniprotkb:BRCA1-associated protein 1(gene name synonym)|uniprotkb:Cerebral protein 6(gene name synonym) psi-mi:psmd2_human(display_long)|uniprotkb:PSMD2(gene name)|psi-mi:PSMD2(display_short)|uniprotkb:TRAP2(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN1(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S2(gene name synonym)|uniprotkb:26S proteasome subunit p97(gene name synonym)|uniprotkb:Tumor necrosis factor type 1 receptor-associated protein 2(gene name synonym)|uniprotkb:Protein 55.11(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830949|imex:IM-21659-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-47004N|refseq:NP_004647.1|ensembl:ENSG00000163930(gene)|ensembl:ENST00000460680(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003682"(chromatin binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061519"(macrophage homeostasis)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q92560|reactome:R-HSA-5689603|reactome:R-HSA-5693565|uniprotkb:Q92560(identity)|ddbj/embl/genbank:BC001596(identity)|entrezgene/locuslink:8314(identity) refseq:NP_001265637.1|refseq:NP_001265638.1|refseq:NP_002799.3|ensembl:ENSG00000175166(gene)|ensembl:ENST00000310118(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040892|interpro:IPR041433|mint:Q13200|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|rcsb pdb:5VHM|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|rcsb pdb:6MSB|rcsb pdb:6MSD|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-5668541|dip:DIP-38204N|uniprotkb:Q13200(identity)|entrezgene/locuslink:5708(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:GMWdT1u5HUl29N+YgC/bCKTbxm49606 rogid:wujS1i4Gs3gWNinOey4oKsshA+g9606 intact-crc:D8F19ED7A1FEFCE8|rigid:Sr6C8aW8XMCew5JCU1mAP1hX2ds false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92560 uniprotkb:P85037 intact:EBI-1791447|uniprotkb:Q6LEM0|uniprotkb:Q7Z5E8|uniprotkb:A8K993|intact:EBI-2558090|ensembl:ENSP00000417132 intact:EBI-2509974|ensembl:ENSP00000328720 psi-mi:bap1_human(display_long)|uniprotkb:BAP1(gene name)|psi-mi:BAP1(display_short)|uniprotkb:KIAA0272(gene name synonym)|uniprotkb:hucep-6(orf name)|uniprotkb:BRCA1-associated protein 1(gene name synonym)|uniprotkb:Cerebral protein 6(gene name synonym) psi-mi:foxk1_human(display_long)|uniprotkb:FOXK1(gene name)|psi-mi:FOXK1(display_short)|uniprotkb:MNF(gene name synonym)|uniprotkb:Myocyte nuclear factor(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830949|imex:IM-21659-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-47004N|refseq:NP_004647.1|ensembl:ENSG00000163930(gene)|ensembl:ENST00000460680(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003682"(chromatin binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061519"(macrophage homeostasis)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q92560|reactome:R-HSA-5689603|reactome:R-HSA-5693565|uniprotkb:Q92560(identity)|ddbj/embl/genbank:BC001596(identity)|entrezgene/locuslink:8314(identity) ensembl:ENSG00000164916(gene)|ensembl:ENST00000328914(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0042594"(response to starvation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5689603|refseq:XP_011513493.1|refseq:NP_001032242.1|uniprotkb:P85037(identity)|entrezgene/locuslink:221937(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:GMWdT1u5HUl29N+YgC/bCKTbxm49606 rogid:ngoE3oNlIDGkTf1ZMYG4OQ6lvE09606 intact-crc:D8F19ED7A1FEFCE8|rigid:Sr6C8aW8XMCew5JCU1mAP1hX2ds false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92560 uniprotkb:P51665 intact:EBI-1791447|uniprotkb:Q6LEM0|uniprotkb:Q7Z5E8|uniprotkb:A8K993|intact:EBI-2558090|ensembl:ENSP00000417132 intact:EBI-357659|uniprotkb:Q6PKI2|uniprotkb:Q96E97|ensembl:ENSP00000219313|uniprotkb:D3DWS9 psi-mi:bap1_human(display_long)|uniprotkb:BAP1(gene name)|psi-mi:BAP1(display_short)|uniprotkb:KIAA0272(gene name synonym)|uniprotkb:hucep-6(orf name)|uniprotkb:BRCA1-associated protein 1(gene name synonym)|uniprotkb:Cerebral protein 6(gene name synonym) psi-mi:psmd7_human(display_long)|uniprotkb:PSMD7(gene name)|psi-mi:PSMD7(display_short)|uniprotkb:MOV34L(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN8(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S12(gene name synonym)|uniprotkb:Proteasome subunit p40(gene name synonym)|uniprotkb:Mov34 protein homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830949|imex:IM-21659-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-47004N|refseq:NP_004647.1|ensembl:ENSG00000163930(gene)|ensembl:ENST00000460680(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003682"(chromatin binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061519"(macrophage homeostasis)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q92560|reactome:R-HSA-5689603|reactome:R-HSA-5693565|uniprotkb:Q92560(identity)|ddbj/embl/genbank:BC001596(identity)|entrezgene/locuslink:8314(identity) refseq:NP_002802.2|rcsb pdb:5T0J|ensembl:ENSG00000103035(gene)|ensembl:ENST00000219313(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0016020"(membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070122"(isopeptidase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR033858|interpro:IPR037518|mint:P51665|rcsb pdb:2O95|rcsb pdb:2O96|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-180534|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-195253|reactome:R-HSA-5676590|reactome:R-HSA-202424|reactome:R-HSA-5678895|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-2871837|reactome:R-HSA-5689880|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-6798695|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-68827|reactome:R-HSA-4641258|reactome:R-HSA-68949|reactome:R-HSA-5358346|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-27572N|uniprotkb:P51665(identity)|entrezgene/locuslink:5713(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:GMWdT1u5HUl29N+YgC/bCKTbxm49606 rogid:HJaBTx4pIiSDIArqueuNRvhzVvU9606 intact-crc:D8F19ED7A1FEFCE8|rigid:Sr6C8aW8XMCew5JCU1mAP1hX2ds false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92560 uniprotkb:Q9P035 intact:EBI-1791447|uniprotkb:Q6LEM0|uniprotkb:Q7Z5E8|uniprotkb:A8K993|intact:EBI-2558090|ensembl:ENSP00000417132 intact:EBI-359013|intact:EBI-1049123|uniprotkb:A0PJA1|uniprotkb:Q280Z3|uniprotkb:Q6PD63|uniprotkb:Q8IUI5|uniprotkb:Q8NC86|uniprotkb:Q8NCB1|uniprotkb:Q96T12|uniprotkb:Q9NQA7|uniprotkb:B4DRF4|intact:EBI-28973764|ensembl:ENSP00000261875 psi-mi:bap1_human(display_long)|uniprotkb:BAP1(gene name)|psi-mi:BAP1(display_short)|uniprotkb:KIAA0272(gene name synonym)|uniprotkb:hucep-6(orf name)|uniprotkb:BRCA1-associated protein 1(gene name synonym)|uniprotkb:Cerebral protein 6(gene name synonym) psi-mi:hacd3_human(display_long)|uniprotkb:Butyrate-induced protein 1(gene name synonym)|uniprotkb:PTPLAD1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase-like A domain-containing protein 1(gene name synonym)|uniprotkb:HACD3(gene name)|psi-mi:HACD3(display_short)|uniprotkb:3-hydroxyacyl-CoA dehydratase 3(gene name synonym)|uniprotkb:BIND1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830949|imex:IM-21659-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-47004N|refseq:NP_004647.1|ensembl:ENSG00000163930(gene)|ensembl:ENST00000460680(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003682"(chromatin binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061519"(macrophage homeostasis)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q92560|reactome:R-HSA-5689603|reactome:R-HSA-5693565|uniprotkb:Q92560(identity)|ddbj/embl/genbank:BC001596(identity)|entrezgene/locuslink:8314(identity) ensembl:ENSP00000261875|ensembl:ENST00000442729|ensembl:ENSP00000392491|refseq:NP_057479.2|ensembl:ENSG00000074696(gene)|ensembl:ENST00000261875(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005925"(focal adhesion)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0018812"(3-hydroxyacyl-CoA dehydratase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030497"(fatty acid elongation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0102158"(very-long-chain 3-hydroxyacyl-CoA dehydratase activity)|go:"GO:0102343"(3-hydroxy-arachidoyl-CoA dehydratase activity)|go:"GO:0102344"(3-hydroxy-behenoyl-CoA dehydratase activity)|go:"GO:0102345"(3-hydroxy-lignoceroyl-CoA dehydratase activity)|interpro:IPR007052(CS domain)|interpro:IPR007482(Protein-tyrosine phosphatase-like, PTPLA)|interpro:IPR008978(HSP20-like chaperone)|mint:Q9P035|reactome:R-HSA-75876|uniprotkb:Q9P035(identity)|entrezgene/locuslink:51495(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:GMWdT1u5HUl29N+YgC/bCKTbxm49606 rogid:U31K6H8I2f5j7FRhfHiY0cG4smA9606 intact-crc:D8F19ED7A1FEFCE8|rigid:Sr6C8aW8XMCew5JCU1mAP1hX2ds false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92560 uniprotkb:P62195 intact:EBI-1791447|uniprotkb:Q6LEM0|uniprotkb:Q7Z5E8|uniprotkb:A8K993|intact:EBI-2558090|ensembl:ENSP00000417132 intact:EBI-357745|uniprotkb:O35051|uniprotkb:O43208|uniprotkb:P52915|uniprotkb:P47210|uniprotkb:P52916|uniprotkb:A8K763|uniprotkb:A8K3Z3|ensembl:ENSP00000310572 psi-mi:bap1_human(display_long)|uniprotkb:BAP1(gene name)|psi-mi:BAP1(display_short)|uniprotkb:KIAA0272(gene name synonym)|uniprotkb:hucep-6(orf name)|uniprotkb:BRCA1-associated protein 1(gene name synonym)|uniprotkb:Cerebral protein 6(gene name synonym) psi-mi:prs8_human(display_long)|uniprotkb:PSMC5(gene name)|psi-mi:PSMC5(display_short)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 5(gene name synonym)|uniprotkb:Proteasome subunit p45(gene name synonym)|uniprotkb:p45/SUG(gene name synonym)|uniprotkb:Thyroid hormone receptor-interacting protein 1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830949|imex:IM-21659-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-47004N|refseq:NP_004647.1|ensembl:ENSG00000163930(gene)|ensembl:ENST00000460680(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003682"(chromatin binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061519"(macrophage homeostasis)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q92560|reactome:R-HSA-5689603|reactome:R-HSA-5693565|uniprotkb:Q92560(identity)|ddbj/embl/genbank:BC001596(identity)|entrezgene/locuslink:8314(identity) refseq:NP_001186092.1|refseq:NP_002796.4|reactome:R-HSA-195253|ensembl:ENSG00000087191(gene)|ensembl:ENST00000310144(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031531"(thyrotropin-releasing hormone receptor binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|mint:P62195|rcsb pdb:2KRK|rcsb pdb:3KW6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-36645N|uniprotkb:P62195(identity)|entrezgene/locuslink:5705(identity) psi-mi:"MI:0469"(intact) - crc64:29C6410C4A85A7F7 figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:GMWdT1u5HUl29N+YgC/bCKTbxm49606 rogid:zgUTOX/O4m86U/Nf+pnT7u0m0gY9606 intact-crc:D8F19ED7A1FEFCE8|rigid:Sr6C8aW8XMCew5JCU1mAP1hX2ds false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92560 uniprotkb:P51610 intact:EBI-1791447|uniprotkb:Q6LEM0|uniprotkb:Q7Z5E8|uniprotkb:A8K993|intact:EBI-2558090|ensembl:ENSP00000417132 intact:EBI-396176|intact:EBI-2832627|uniprotkb:Q6P4G5|intact:EBI-12037257|intact:EBI-14324845|ensembl:ENSP00000309555|intact:EBI-12980473 psi-mi:bap1_human(display_long)|uniprotkb:BAP1(gene name)|psi-mi:BAP1(display_short)|uniprotkb:KIAA0272(gene name synonym)|uniprotkb:hucep-6(orf name)|uniprotkb:BRCA1-associated protein 1(gene name synonym)|uniprotkb:Cerebral protein 6(gene name synonym) psi-mi:hcfc1_human(display_long)|uniprotkb:HCFC1(gene name)|psi-mi:HCFC1(display_short)|uniprotkb:HCF1(gene name synonym)|uniprotkb:C1 factor(gene name synonym)|uniprotkb:VP16 accessory protein(gene name synonym)|uniprotkb:VCAF(gene name synonym)|uniprotkb:CFF(gene name synonym)|uniprotkb:HFC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830949|imex:IM-21659-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-47004N|refseq:NP_004647.1|ensembl:ENSG00000163930(gene)|ensembl:ENST00000460680(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003682"(chromatin binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061519"(macrophage homeostasis)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q92560|reactome:R-HSA-5689603|reactome:R-HSA-5693565|uniprotkb:Q92560(identity)|ddbj/embl/genbank:BC001596(identity)|entrezgene/locuslink:8314(identity) refseq:NP_005325.2|refseq:XP_006724879.1|rcsb pdb:6MA1|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|reactome:R-HSA-2151201|reactome:R-HSA-3214847|reactome:R-HSA-5689603|ensembl:ENSG00000172534(gene)|ensembl:ENST00000310441(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019046"(release from viral latency)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR036116|interpro:IPR037854|interpro:IPR043536|mint:P51610|rcsb pdb:4GO6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:5LWV|dip:DIP-32955N|uniprotkb:P51610(identity)|entrezgene/locuslink:3054(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:GMWdT1u5HUl29N+YgC/bCKTbxm49606 rogid:RzsCRe9l6md3DI87H4ZgdR9oBMI9606 intact-crc:D8F19ED7A1FEFCE8|rigid:Sr6C8aW8XMCew5JCU1mAP1hX2ds false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92560 uniprotkb:O43242 intact:EBI-1791447|uniprotkb:Q6LEM0|uniprotkb:Q7Z5E8|uniprotkb:A8K993|intact:EBI-2558090|ensembl:ENSP00000417132 intact:EBI-357622|uniprotkb:Q96EI2|uniprotkb:Q9BQA4|ensembl:ENSP00000264639|uniprotkb:B4DT72|uniprotkb:B3KMW9 psi-mi:bap1_human(display_long)|uniprotkb:BAP1(gene name)|psi-mi:BAP1(display_short)|uniprotkb:KIAA0272(gene name synonym)|uniprotkb:hucep-6(orf name)|uniprotkb:BRCA1-associated protein 1(gene name synonym)|uniprotkb:Cerebral protein 6(gene name synonym) psi-mi:psmd3_human(display_long)|uniprotkb:PSMD3(gene name)|psi-mi:PSMD3(display_short)|uniprotkb:Proteasome subunit p58(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S3(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830949|imex:IM-21659-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-47004N|refseq:NP_004647.1|ensembl:ENSG00000163930(gene)|ensembl:ENST00000460680(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003682"(chromatin binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061519"(macrophage homeostasis)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q92560|reactome:R-HSA-5689603|reactome:R-HSA-5693565|uniprotkb:Q92560(identity)|ddbj/embl/genbank:BC001596(identity)|entrezgene/locuslink:8314(identity) ensembl:ENSG00000108344(gene)|ensembl:ENST00000264639(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013586(26S proteasome regulatory subunit, C-terminal)|interpro:IPR035267|interpro:IPR036390|mint:O43242|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|reactome:R-HSA-174113|reactome:R-HSA-174154|rcsb pdb:5VHH|rcsb pdb:5VHI|reactome:R-HSA-174178|rcsb pdb:5VHS|reactome:R-HSA-174184|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|reactome:R-HSA-180534|rcsb pdb:6MSJ|reactome:R-HSA-180585|reactome:R-HSA-187577|rcsb pdb:6MSK|reactome:R-HSA-195253|reactome:R-HSA-202424|rcsb pdb:6WJD|reactome:R-HSA-211733|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-174084|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5607761|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-8854050|refseq:NP_002800.2|dip:DIP-27571N|uniprotkb:O43242(identity)|entrezgene/locuslink:5709(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:GMWdT1u5HUl29N+YgC/bCKTbxm49606 rogid:C6CStW89nIAA3mzubyv5wfBwPHk9606 intact-crc:D8F19ED7A1FEFCE8|rigid:Sr6C8aW8XMCew5JCU1mAP1hX2ds false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92560 uniprotkb:P48556 intact:EBI-1791447|uniprotkb:Q6LEM0|uniprotkb:Q7Z5E8|uniprotkb:A8K993|intact:EBI-2558090|ensembl:ENSP00000417132 intact:EBI-359304|uniprotkb:Q6P1L7|uniprotkb:B4DX18|ensembl:ENSP00000215071|ensembl:ENSP00000481136 psi-mi:bap1_human(display_long)|uniprotkb:BAP1(gene name)|psi-mi:BAP1(display_short)|uniprotkb:KIAA0272(gene name synonym)|uniprotkb:hucep-6(orf name)|uniprotkb:BRCA1-associated protein 1(gene name synonym)|uniprotkb:Cerebral protein 6(gene name synonym) psi-mi:psmd8_human(display_long)|uniprotkb:PSMD8(gene name)|psi-mi:PSMD8(display_short)|uniprotkb:26S proteasome regulatory subunit S14(gene name synonym)|uniprotkb:p31(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN12(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830949|imex:IM-21659-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-47004N|refseq:NP_004647.1|ensembl:ENSG00000163930(gene)|ensembl:ENST00000460680(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003682"(chromatin binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061519"(macrophage homeostasis)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q92560|reactome:R-HSA-5689603|reactome:R-HSA-5693565|uniprotkb:Q92560(identity)|ddbj/embl/genbank:BC001596(identity)|entrezgene/locuslink:8314(identity) refseq:NP_002803.2|ensembl:ENSG00000099341(gene)|ensembl:ENST00000215071(transcript)|ensembl:ENST00000620216(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR006746(26S proteasome non-ATPase regulatory subunit Rpn12)|interpro:IPR033464|mint:P48556|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5M32|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-180534|uniprotkb:P48556(identity)|entrezgene/locuslink:5714(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:GMWdT1u5HUl29N+YgC/bCKTbxm49606 rogid:73qmlkzCwdeHlNzUy7vy7qmIok09606 intact-crc:D8F19ED7A1FEFCE8|rigid:Sr6C8aW8XMCew5JCU1mAP1hX2ds false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92560 uniprotkb:Q8NB78 intact:EBI-1791447|uniprotkb:Q6LEM0|uniprotkb:Q7Z5E8|uniprotkb:A8K993|intact:EBI-2558090|ensembl:ENSP00000417132 intact:EBI-2509999|ensembl:ENSP00000499208|uniprotkb:Q6AI15|uniprotkb:Q6ZUU4|uniprotkb:Q96EL7|uniprotkb:Q5TGV3|uniprotkb:Q8N258|uniprotkb:A2A2C5|uniprotkb:A2A2C6 psi-mi:bap1_human(display_long)|uniprotkb:BAP1(gene name)|psi-mi:BAP1(display_short)|uniprotkb:KIAA0272(gene name synonym)|uniprotkb:hucep-6(orf name)|uniprotkb:BRCA1-associated protein 1(gene name synonym)|uniprotkb:Cerebral protein 6(gene name synonym) psi-mi:kdm1b_human(display_long)|uniprotkb:KDM1B(gene name)|psi-mi:KDM1B(display_short)|uniprotkb:C6orf193(gene name synonym)|uniprotkb:AOF1(gene name synonym)|uniprotkb:LSD2(gene name synonym)|uniprotkb:Lysine-specific histone demethylase 2(gene name synonym)|uniprotkb:Flavin-containing amine oxidase domain-containing protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830949|imex:IM-21659-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-47004N|refseq:NP_004647.1|ensembl:ENSG00000163930(gene)|ensembl:ENST00000460680(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003682"(chromatin binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061519"(macrophage homeostasis)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q92560|reactome:R-HSA-5689603|reactome:R-HSA-5693565|uniprotkb:Q92560(identity)|ddbj/embl/genbank:BC001596(identity)|entrezgene/locuslink:8314(identity) ensembl:ENSG00000165097(gene)|ensembl:ENST00000650836(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000786"(nucleosome)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034649"("obsolete histone demethylase activity (H3-monomethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042393"(histone binding)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0071949"(FAD binding)|interpro:IPR002937(Amine oxidase)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR011124(Zinc finger, CW-type)|interpro:IPR036188|interpro:IPR036388|rcsb pdb:4FWE|rcsb pdb:4FWF|rcsb pdb:4FWJ|rcsb pdb:4GU0|rcsb pdb:4GU1|rcsb pdb:4GUR|rcsb pdb:4GUS|rcsb pdb:4GUT|rcsb pdb:4GUU|rcsb pdb:4HSU|rcsb pdb:6R1U|rcsb pdb:6R25|reactome:R-HSA-3214842|reactome:R-HSA-5689603|reactome:R-HSA-9029569|refseq:NP_694587.3|refseq:XP_005248983.1|uniprotkb:Q8NB78(identity)|entrezgene/locuslink:221656(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:GMWdT1u5HUl29N+YgC/bCKTbxm49606 rogid:37lP46UxrdbQmFoKabg6UdpVETg9606 intact-crc:D8F19ED7A1FEFCE8|rigid:Sr6C8aW8XMCew5JCU1mAP1hX2ds false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92560 uniprotkb:P51571 intact:EBI-1791447|uniprotkb:Q6LEM0|uniprotkb:Q7Z5E8|uniprotkb:A8K993|intact:EBI-2558090|ensembl:ENSP00000417132 intact:EBI-1054539|uniprotkb:Q53XY1|uniprotkb:A8K378|ensembl:ENSP00000317331|ensembl:ENSP00000359103|ensembl:ENSP00000359104 psi-mi:bap1_human(display_long)|uniprotkb:BAP1(gene name)|psi-mi:BAP1(display_short)|uniprotkb:KIAA0272(gene name synonym)|uniprotkb:hucep-6(orf name)|uniprotkb:BRCA1-associated protein 1(gene name synonym)|uniprotkb:Cerebral protein 6(gene name synonym) psi-mi:ssrd_human(display_long)|uniprotkb:Signal sequence receptor subunit delta(gene name synonym)|uniprotkb:SSR4(gene name)|psi-mi:SSR4(display_short)|uniprotkb:TRAPD(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830949|imex:IM-21659-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-47004N|refseq:NP_004647.1|ensembl:ENSG00000163930(gene)|ensembl:ENST00000460680(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003682"(chromatin binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061519"(macrophage homeostasis)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q92560|reactome:R-HSA-5689603|reactome:R-HSA-5693565|uniprotkb:Q92560(identity)|ddbj/embl/genbank:BC001596(identity)|entrezgene/locuslink:8314(identity) refseq:NP_001191455.1|refseq:NP_006271.1|refseq:XP_011529488.1|refseq:XP_011529489.1|ensembl:ENSG00000180879(gene)|ensembl:ENST00000320857(transcript)|ensembl:ENST00000370086(transcript)|ensembl:ENST00000370087(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008855(Translocon-associated)|mint:P51571|reactome:R-HSA-1799339|uniprotkb:P51571(identity)|entrezgene/locuslink:6748(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:GMWdT1u5HUl29N+YgC/bCKTbxm49606 rogid:2SNgZQH/jwi61UcuHUf7RYKZH589606 intact-crc:D8F19ED7A1FEFCE8|rigid:Sr6C8aW8XMCew5JCU1mAP1hX2ds false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92560 uniprotkb:Q9Y5Z7 intact:EBI-1791447|uniprotkb:Q6LEM0|uniprotkb:Q7Z5E8|uniprotkb:A8K993|intact:EBI-2558090|ensembl:ENSP00000417132 intact:EBI-592728|uniprotkb:B2R8Q5|uniprotkb:C0H5X3|ensembl:ENSP00000229330 psi-mi:bap1_human(display_long)|uniprotkb:BAP1(gene name)|psi-mi:BAP1(display_short)|uniprotkb:KIAA0272(gene name synonym)|uniprotkb:hucep-6(orf name)|uniprotkb:BRCA1-associated protein 1(gene name synonym)|uniprotkb:Cerebral protein 6(gene name synonym) psi-mi:hcfc2_human(display_long)|uniprotkb:C2 factor(gene name synonym)|uniprotkb:HCFC2(gene name)|psi-mi:HCFC2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8830949|imex:IM-21659-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-47004N|refseq:NP_004647.1|ensembl:ENSG00000163930(gene)|ensembl:ENST00000460680(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003682"(chromatin binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061519"(macrophage homeostasis)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q92560|reactome:R-HSA-5689603|reactome:R-HSA-5693565|uniprotkb:Q92560(identity)|ddbj/embl/genbank:BC001596(identity)|entrezgene/locuslink:8314(identity) refseq:NP_037452.1|ensembl:ENSG00000111727(gene)|ensembl:ENST00000229330(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016032"(viral process)|go:"GO:0016604"(nuclear body)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0071339"(MLL1 complex)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR036116|interpro:IPR037932|interpro:IPR043536|mint:Q9Y5Z7|uniprotkb:Q9Y5Z7(identity)|entrezgene/locuslink:29915(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:GMWdT1u5HUl29N+YgC/bCKTbxm49606 rogid:ytE7Aid9JO9RWsRpJPpBbylLRXo9606 intact-crc:D8F19ED7A1FEFCE8|rigid:Sr6C8aW8XMCew5JCU1mAP1hX2ds false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JN0 uniprotkb:Q15910 intact:EBI-746045|uniprotkb:Q9H945|uniprotkb:Q9Y457|ensembl:ENSP00000348298|ensembl:ENSP00000360138|ensembl:ENSP00000360144|ensembl:ENSP00000501560|ensembl:ENSP00000501639|ensembl:ENSP00000502633|intact:EBI-8833163|uniprotkb:D3DR47|uniprotkb:Q5VW16|uniprotkb:Q7Z723|uniprotkb:Q86T32|uniprotkb:Q86T33|uniprotkb:Q8N3L6|uniprotkb:Q8N655 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 psi-mi:lcor_human(display_long)|uniprotkb:LCOR(gene name)|psi-mi:LCOR(display_short)|uniprotkb:C10orf12(gene name synonym)|uniprotkb:KIAA1795(gene name synonym)|uniprotkb:MLR2(gene name synonym)|uniprotkb:Mblk1-related protein 2(gene name synonym) psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831055|imex:IM-21659-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196233(gene)|ensembl:ENST00000356016(transcript)|ensembl:ENST00000371097(transcript)|ensembl:ENST00000371103(transcript)|ensembl:ENST00000675471(transcript)|ensembl:ENST00000675537(transcript)|ensembl:ENST00000675971(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|mint:Q96JN0|rcsb pdb:2COB|refseq:NP_001164236.1|refseq:NP_001164237.1|refseq:NP_115816.2|refseq:XP_016872275.1|refseq:XP_016872276.1|refseq:XP_016872277.1|refseq:NP_001333445.1|uniprotkb:Q8N655(identity)|entrezgene/locuslink:26148(identity)|ddbj/embl/genbank:BC024315(identity) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N|uniprotkb:Q15910(identity)|entrezgene/locuslink:2146(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:cOnk6EDDff86yaG1uG+dxEQ1Z689606 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 intact-crc:166C7796C9D508AA|rigid:AhX6sgxazM46UXGfCtleMilCMAY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JN0 uniprotkb:Q9Y483 intact:EBI-746045|uniprotkb:Q9H945|uniprotkb:Q9Y457|ensembl:ENSP00000348298|ensembl:ENSP00000360138|ensembl:ENSP00000360144|ensembl:ENSP00000501560|ensembl:ENSP00000501639|ensembl:ENSP00000502633|intact:EBI-8833163|uniprotkb:D3DR47|uniprotkb:Q5VW16|uniprotkb:Q7Z723|uniprotkb:Q86T32|uniprotkb:Q86T33|uniprotkb:Q8N3L6|uniprotkb:Q8N655 intact:EBI-725816|uniprotkb:A6NGQ9|uniprotkb:Q9UES9|uniprotkb:Q9UP40|uniprotkb:A8K2Q3|uniprotkb:B1AKT5|intact:EBI-11028207|uniprotkb:Q96G26|uniprotkb:B1AKT6|ensembl:ENSP00000359321 psi-mi:lcor_human(display_long)|uniprotkb:LCOR(gene name)|psi-mi:LCOR(display_short)|uniprotkb:C10orf12(gene name synonym)|uniprotkb:KIAA1795(gene name synonym)|uniprotkb:MLR2(gene name synonym)|uniprotkb:Mblk1-related protein 2(gene name synonym) psi-mi:mtf2_human(display_long)|uniprotkb:PCL2(gene name synonym)|uniprotkb:Metal-response element DNA-binding protein M96(gene name synonym)|uniprotkb:Metal regulatory transcription factor 2(gene name synonym)|uniprotkb:Polycomb-like protein 2(gene name synonym)|uniprotkb:MTF2(gene name)|psi-mi:MTF2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831055|imex:IM-21659-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196233(gene)|ensembl:ENST00000356016(transcript)|ensembl:ENST00000371097(transcript)|ensembl:ENST00000371103(transcript)|ensembl:ENST00000675471(transcript)|ensembl:ENST00000675537(transcript)|ensembl:ENST00000675971(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|mint:Q96JN0|rcsb pdb:2COB|refseq:NP_001164236.1|refseq:NP_001164237.1|refseq:NP_115816.2|refseq:XP_016872275.1|refseq:XP_016872276.1|refseq:XP_016872277.1|refseq:NP_001333445.1|uniprotkb:Q8N655(identity)|entrezgene/locuslink:26148(identity)|ddbj/embl/genbank:BC024315(identity) refseq:NP_001157863.1|refseq:NP_001157865.1|refseq:NP_031384.1|refseq:XP_011539318.1|refseq:XP_016856165.1|ensembl:ENSG00000143033(gene)|ensembl:ENST00000370298(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042015|mint:Q9Y483|rcsb pdb:5XFR|reactome:R-HSA-212300|interpro:IPR042014|refseq:NP_001157864.1|uniprotkb:Q9Y483(identity)|entrezgene/locuslink:22823(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:cOnk6EDDff86yaG1uG+dxEQ1Z689606 rogid:Im8E6U/OPb8AEir43AUUDlU6F2o9606 intact-crc:166C7796C9D508AA|rigid:AhX6sgxazM46UXGfCtleMilCMAY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JN0 uniprotkb:P48643 intact:EBI-746045|uniprotkb:Q9H945|uniprotkb:Q9Y457|ensembl:ENSP00000348298|ensembl:ENSP00000360138|ensembl:ENSP00000360144|ensembl:ENSP00000501560|ensembl:ENSP00000501639|ensembl:ENSP00000502633|intact:EBI-8833163|uniprotkb:D3DR47|uniprotkb:Q5VW16|uniprotkb:Q7Z723|uniprotkb:Q86T32|uniprotkb:Q86T33|uniprotkb:Q8N3L6|uniprotkb:Q8N655 intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8 psi-mi:lcor_human(display_long)|uniprotkb:LCOR(gene name)|psi-mi:LCOR(display_short)|uniprotkb:C10orf12(gene name synonym)|uniprotkb:KIAA1795(gene name synonym)|uniprotkb:MLR2(gene name synonym)|uniprotkb:Mblk1-related protein 2(gene name synonym) psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831055|imex:IM-21659-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196233(gene)|ensembl:ENST00000356016(transcript)|ensembl:ENST00000371097(transcript)|ensembl:ENST00000371103(transcript)|ensembl:ENST00000675471(transcript)|ensembl:ENST00000675537(transcript)|ensembl:ENST00000675971(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|mint:Q96JN0|rcsb pdb:2COB|refseq:NP_001164236.1|refseq:NP_001164237.1|refseq:NP_115816.2|refseq:XP_016872275.1|refseq:XP_016872276.1|refseq:XP_016872277.1|refseq:NP_001333445.1|uniprotkb:Q8N655(identity)|entrezgene/locuslink:26148(identity)|ddbj/embl/genbank:BC024315(identity) refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N|uniprotkb:P48643(identity)|entrezgene/locuslink:22948(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:cOnk6EDDff86yaG1uG+dxEQ1Z689606 rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606 intact-crc:166C7796C9D508AA|rigid:AhX6sgxazM46UXGfCtleMilCMAY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JN0 uniprotkb:P40227 intact:EBI-746045|uniprotkb:Q9H945|uniprotkb:Q9Y457|ensembl:ENSP00000348298|ensembl:ENSP00000360138|ensembl:ENSP00000360144|ensembl:ENSP00000501560|ensembl:ENSP00000501639|ensembl:ENSP00000502633|intact:EBI-8833163|uniprotkb:D3DR47|uniprotkb:Q5VW16|uniprotkb:Q7Z723|uniprotkb:Q86T32|uniprotkb:Q86T33|uniprotkb:Q8N3L6|uniprotkb:Q8N655 intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2 psi-mi:lcor_human(display_long)|uniprotkb:LCOR(gene name)|psi-mi:LCOR(display_short)|uniprotkb:C10orf12(gene name synonym)|uniprotkb:KIAA1795(gene name synonym)|uniprotkb:MLR2(gene name synonym)|uniprotkb:Mblk1-related protein 2(gene name synonym) psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831055|imex:IM-21659-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196233(gene)|ensembl:ENST00000356016(transcript)|ensembl:ENST00000371097(transcript)|ensembl:ENST00000371103(transcript)|ensembl:ENST00000675471(transcript)|ensembl:ENST00000675537(transcript)|ensembl:ENST00000675971(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|mint:Q96JN0|rcsb pdb:2COB|refseq:NP_001164236.1|refseq:NP_001164237.1|refseq:NP_115816.2|refseq:XP_016872275.1|refseq:XP_016872276.1|refseq:XP_016872277.1|refseq:NP_001333445.1|uniprotkb:Q8N655(identity)|entrezgene/locuslink:26148(identity)|ddbj/embl/genbank:BC024315(identity) refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N|uniprotkb:P40227(identity)|entrezgene/locuslink:908(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:cOnk6EDDff86yaG1uG+dxEQ1Z689606 rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606 intact-crc:166C7796C9D508AA|rigid:AhX6sgxazM46UXGfCtleMilCMAY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JN0 uniprotkb:O43189 intact:EBI-746045|uniprotkb:Q9H945|uniprotkb:Q9Y457|ensembl:ENSP00000348298|ensembl:ENSP00000360138|ensembl:ENSP00000360144|ensembl:ENSP00000501560|ensembl:ENSP00000501639|ensembl:ENSP00000502633|intact:EBI-8833163|uniprotkb:D3DR47|uniprotkb:Q5VW16|uniprotkb:Q7Z723|uniprotkb:Q86T32|uniprotkb:Q86T33|uniprotkb:Q8N3L6|uniprotkb:Q8N655 intact:EBI-530034|uniprotkb:B1AZX2|uniprotkb:B1AZX3|uniprotkb:O60929|uniprotkb:Q96KM7|uniprotkb:Q5SU07|uniprotkb:Q5SU08|ensembl:ENSP00000363640|ensembl:ENSP00000391901|ensembl:ENSP00000407295 psi-mi:lcor_human(display_long)|uniprotkb:LCOR(gene name)|psi-mi:LCOR(display_short)|uniprotkb:C10orf12(gene name synonym)|uniprotkb:KIAA1795(gene name synonym)|uniprotkb:MLR2(gene name synonym)|uniprotkb:Mblk1-related protein 2(gene name synonym) psi-mi:phf1_human(display_long)|uniprotkb:PCL1(gene name synonym)|uniprotkb:Polycomb-like protein 1(gene name synonym)|uniprotkb:PHF1(gene name)|psi-mi:PHF1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831055|imex:IM-21659-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196233(gene)|ensembl:ENST00000356016(transcript)|ensembl:ENST00000371097(transcript)|ensembl:ENST00000371103(transcript)|ensembl:ENST00000675471(transcript)|ensembl:ENST00000675537(transcript)|ensembl:ENST00000675971(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|mint:Q96JN0|rcsb pdb:2COB|refseq:NP_001164236.1|refseq:NP_001164237.1|refseq:NP_115816.2|refseq:XP_016872275.1|refseq:XP_016872276.1|refseq:XP_016872277.1|refseq:NP_001333445.1|uniprotkb:Q8N655(identity)|entrezgene/locuslink:26148(identity)|ddbj/embl/genbank:BC024315(identity) refseq:XP_011512964.1|refseq:NP_002627.1|refseq:NP_077084.1|ensembl:ENSG00000112511(gene)|ensembl:ENSG00000225553(gene)|ensembl:ENST00000374516(transcript)|ensembl:ENST00000427869(transcript)|ensembl:ENST00000454914(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR031202|interpro:IPR040477|mint:O43189|rcsb pdb:2E5P|rcsb pdb:2M0O|rcsb pdb:4HCZ|rcsb pdb:5XFN|rcsb pdb:5XFO|rcsb pdb:5XFP|rcsb pdb:6WAT|rcsb pdb:6WAV|reactome:R-HSA-212300|dip:DIP-34001N|uniprotkb:O43189(identity)|entrezgene/locuslink:5252(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:cOnk6EDDff86yaG1uG+dxEQ1Z689606 rogid:8n8g2LqzuOQb8cFC7tE1j/xBvkI9606 intact-crc:166C7796C9D508AA|rigid:AhX6sgxazM46UXGfCtleMilCMAY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JN0 uniprotkb:O75530 intact:EBI-746045|uniprotkb:Q9H945|uniprotkb:Q9Y457|ensembl:ENSP00000348298|ensembl:ENSP00000360138|ensembl:ENSP00000360144|ensembl:ENSP00000501560|ensembl:ENSP00000501639|ensembl:ENSP00000502633|intact:EBI-8833163|uniprotkb:D3DR47|uniprotkb:Q5VW16|uniprotkb:Q7Z723|uniprotkb:Q86T32|uniprotkb:Q86T33|uniprotkb:Q8N3L6|uniprotkb:Q8N655 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 psi-mi:lcor_human(display_long)|uniprotkb:LCOR(gene name)|psi-mi:LCOR(display_short)|uniprotkb:C10orf12(gene name synonym)|uniprotkb:KIAA1795(gene name synonym)|uniprotkb:MLR2(gene name synonym)|uniprotkb:Mblk1-related protein 2(gene name synonym) psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831055|imex:IM-21659-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196233(gene)|ensembl:ENST00000356016(transcript)|ensembl:ENST00000371097(transcript)|ensembl:ENST00000371103(transcript)|ensembl:ENST00000675471(transcript)|ensembl:ENST00000675537(transcript)|ensembl:ENST00000675971(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|mint:Q96JN0|rcsb pdb:2COB|refseq:NP_001164236.1|refseq:NP_001164237.1|refseq:NP_115816.2|refseq:XP_016872275.1|refseq:XP_016872276.1|refseq:XP_016872277.1|refseq:NP_001333445.1|uniprotkb:Q8N655(identity)|entrezgene/locuslink:26148(identity)|ddbj/embl/genbank:BC024315(identity) refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:O75530(identity)|entrezgene/locuslink:8726(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:cOnk6EDDff86yaG1uG+dxEQ1Z689606 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 intact-crc:166C7796C9D508AA|rigid:AhX6sgxazM46UXGfCtleMilCMAY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JN0 uniprotkb:P78371 intact:EBI-746045|uniprotkb:Q9H945|uniprotkb:Q9Y457|ensembl:ENSP00000348298|ensembl:ENSP00000360138|ensembl:ENSP00000360144|ensembl:ENSP00000501560|ensembl:ENSP00000501639|ensembl:ENSP00000502633|intact:EBI-8833163|uniprotkb:D3DR47|uniprotkb:Q5VW16|uniprotkb:Q7Z723|uniprotkb:Q86T32|uniprotkb:Q86T33|uniprotkb:Q8N3L6|uniprotkb:Q8N655 intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300 psi-mi:lcor_human(display_long)|uniprotkb:LCOR(gene name)|psi-mi:LCOR(display_short)|uniprotkb:C10orf12(gene name synonym)|uniprotkb:KIAA1795(gene name synonym)|uniprotkb:MLR2(gene name synonym)|uniprotkb:Mblk1-related protein 2(gene name synonym) psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831055|imex:IM-21659-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196233(gene)|ensembl:ENST00000356016(transcript)|ensembl:ENST00000371097(transcript)|ensembl:ENST00000371103(transcript)|ensembl:ENST00000675471(transcript)|ensembl:ENST00000675537(transcript)|ensembl:ENST00000675971(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|mint:Q96JN0|rcsb pdb:2COB|refseq:NP_001164236.1|refseq:NP_001164237.1|refseq:NP_115816.2|refseq:XP_016872275.1|refseq:XP_016872276.1|refseq:XP_016872277.1|refseq:NP_001333445.1|uniprotkb:Q8N655(identity)|entrezgene/locuslink:26148(identity)|ddbj/embl/genbank:BC024315(identity) refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695|uniprotkb:P78371(identity)|entrezgene/locuslink:10576(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:cOnk6EDDff86yaG1uG+dxEQ1Z689606 rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606 intact-crc:166C7796C9D508AA|rigid:AhX6sgxazM46UXGfCtleMilCMAY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JN0 uniprotkb:P62891 intact:EBI-746045|uniprotkb:Q9H945|uniprotkb:Q9Y457|ensembl:ENSP00000348298|ensembl:ENSP00000360138|ensembl:ENSP00000360144|ensembl:ENSP00000501560|ensembl:ENSP00000501639|ensembl:ENSP00000502633|intact:EBI-8833163|uniprotkb:D3DR47|uniprotkb:Q5VW16|uniprotkb:Q7Z723|uniprotkb:Q86T32|uniprotkb:Q86T33|uniprotkb:Q8N3L6|uniprotkb:Q8N655 intact:EBI-8830744|uniprotkb:P02404|uniprotkb:Q9BYF2|uniprotkb:P39025|ensembl:ENSP00000355315 psi-mi:lcor_human(display_long)|uniprotkb:LCOR(gene name)|psi-mi:LCOR(display_short)|uniprotkb:C10orf12(gene name synonym)|uniprotkb:KIAA1795(gene name synonym)|uniprotkb:MLR2(gene name synonym)|uniprotkb:Mblk1-related protein 2(gene name synonym) psi-mi:rl39_human(display_long)|uniprotkb:RPL39(gene name)|psi-mi:RPL39(display_short)|uniprotkb:Large ribosomal subunit protein eL39(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831055|imex:IM-21659-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196233(gene)|ensembl:ENST00000356016(transcript)|ensembl:ENST00000371097(transcript)|ensembl:ENST00000371103(transcript)|ensembl:ENST00000675471(transcript)|ensembl:ENST00000675537(transcript)|ensembl:ENST00000675971(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|mint:Q96JN0|rcsb pdb:2COB|refseq:NP_001164236.1|refseq:NP_001164237.1|refseq:NP_115816.2|refseq:XP_016872275.1|refseq:XP_016872276.1|refseq:XP_016872277.1|refseq:NP_001333445.1|uniprotkb:Q8N655(identity)|entrezgene/locuslink:26148(identity)|ddbj/embl/genbank:BC024315(identity) refseq:NP_000991.1|rcsb pdb:4V6X|ensembl:ENSG00000198918(gene)|ensembl:ENST00000361575(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000077(Ribosomal protein L39e)|interpro:IPR020083|interpro:IPR023626|rcsb pdb:4UG0|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|uniprotkb:P62891(identity)|entrezgene/locuslink:6170(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:cOnk6EDDff86yaG1uG+dxEQ1Z689606 rogid:AZus2dxwJsTxAOwnJ93E2yhasbo9606 intact-crc:166C7796C9D508AA|rigid:AhX6sgxazM46UXGfCtleMilCMAY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JN0 uniprotkb:P35659 intact:EBI-746045|uniprotkb:Q9H945|uniprotkb:Q9Y457|ensembl:ENSP00000348298|ensembl:ENSP00000360138|ensembl:ENSP00000360144|ensembl:ENSP00000501560|ensembl:ENSP00000501639|ensembl:ENSP00000502633|intact:EBI-8833163|uniprotkb:D3DR47|uniprotkb:Q5VW16|uniprotkb:Q7Z723|uniprotkb:Q86T32|uniprotkb:Q86T33|uniprotkb:Q8N3L6|uniprotkb:Q8N655 intact:EBI-301977|uniprotkb:Q5TGV4|uniprotkb:Q5TGV5|uniprotkb:B2R6K6|ensembl:ENSP00000498335|ensembl:ENSP00000498653|uniprotkb:B4DN37 psi-mi:lcor_human(display_long)|uniprotkb:LCOR(gene name)|psi-mi:LCOR(display_short)|uniprotkb:C10orf12(gene name synonym)|uniprotkb:KIAA1795(gene name synonym)|uniprotkb:MLR2(gene name synonym)|uniprotkb:Mblk1-related protein 2(gene name synonym) psi-mi:dek_human(display_long)|uniprotkb:DEK(gene name)|psi-mi:DEK(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831055|imex:IM-21659-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196233(gene)|ensembl:ENST00000356016(transcript)|ensembl:ENST00000371097(transcript)|ensembl:ENST00000371103(transcript)|ensembl:ENST00000675471(transcript)|ensembl:ENST00000675537(transcript)|ensembl:ENST00000675971(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|mint:Q96JN0|rcsb pdb:2COB|refseq:NP_001164236.1|refseq:NP_001164237.1|refseq:NP_115816.2|refseq:XP_016872275.1|refseq:XP_016872276.1|refseq:XP_016872277.1|refseq:NP_001333445.1|uniprotkb:Q8N655(identity)|entrezgene/locuslink:26148(identity)|ddbj/embl/genbank:BC024315(identity) ensembl:ENSG00000124795(gene)|ensembl:ENST00000652576(transcript)|ensembl:ENST00000652689(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0019079"(viral genome replication)|go:"GO:0042393"(histone binding)|go:"GO:0043292"(contractile fiber)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR014876(DEK C terminal)|interpro:IPR044198|mint:P35659|rcsb pdb:1Q1V|rcsb pdb:2JX3|reactome:R-HSA-8864260|reactome:R-HSA-5250924|reactome:R-HSA-9616222|refseq:NP_001128181.1|refseq:NP_003463.1|uniprotkb:P35659(identity)|entrezgene/locuslink:7913(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:cOnk6EDDff86yaG1uG+dxEQ1Z689606 rogid:vHgpAwD3bj+BnjUPeNSIlouymfg9606 intact-crc:166C7796C9D508AA|rigid:AhX6sgxazM46UXGfCtleMilCMAY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JN0 uniprotkb:P50991 intact:EBI-746045|uniprotkb:Q9H945|uniprotkb:Q9Y457|ensembl:ENSP00000348298|ensembl:ENSP00000360138|ensembl:ENSP00000360144|ensembl:ENSP00000501560|ensembl:ENSP00000501639|ensembl:ENSP00000502633|intact:EBI-8833163|uniprotkb:D3DR47|uniprotkb:Q5VW16|uniprotkb:Q7Z723|uniprotkb:Q86T32|uniprotkb:Q86T33|uniprotkb:Q8N3L6|uniprotkb:Q8N655 intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958 psi-mi:lcor_human(display_long)|uniprotkb:LCOR(gene name)|psi-mi:LCOR(display_short)|uniprotkb:C10orf12(gene name synonym)|uniprotkb:KIAA1795(gene name synonym)|uniprotkb:MLR2(gene name synonym)|uniprotkb:Mblk1-related protein 2(gene name synonym) psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831055|imex:IM-21659-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196233(gene)|ensembl:ENST00000356016(transcript)|ensembl:ENST00000371097(transcript)|ensembl:ENST00000371103(transcript)|ensembl:ENST00000675471(transcript)|ensembl:ENST00000675537(transcript)|ensembl:ENST00000675971(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|mint:Q96JN0|rcsb pdb:2COB|refseq:NP_001164236.1|refseq:NP_001164237.1|refseq:NP_115816.2|refseq:XP_016872275.1|refseq:XP_016872276.1|refseq:XP_016872277.1|refseq:NP_001333445.1|uniprotkb:Q8N655(identity)|entrezgene/locuslink:26148(identity)|ddbj/embl/genbank:BC024315(identity) refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998|uniprotkb:P50991(identity)|entrezgene/locuslink:10575(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:cOnk6EDDff86yaG1uG+dxEQ1Z689606 rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606 intact-crc:166C7796C9D508AA|rigid:AhX6sgxazM46UXGfCtleMilCMAY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JN0 uniprotkb:Q15022 intact:EBI-746045|uniprotkb:Q9H945|uniprotkb:Q9Y457|ensembl:ENSP00000348298|ensembl:ENSP00000360138|ensembl:ENSP00000360144|ensembl:ENSP00000501560|ensembl:ENSP00000501639|ensembl:ENSP00000502633|intact:EBI-8833163|uniprotkb:D3DR47|uniprotkb:Q5VW16|uniprotkb:Q7Z723|uniprotkb:Q86T32|uniprotkb:Q86T33|uniprotkb:Q8N3L6|uniprotkb:Q8N655 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 psi-mi:lcor_human(display_long)|uniprotkb:LCOR(gene name)|psi-mi:LCOR(display_short)|uniprotkb:C10orf12(gene name synonym)|uniprotkb:KIAA1795(gene name synonym)|uniprotkb:MLR2(gene name synonym)|uniprotkb:Mblk1-related protein 2(gene name synonym) psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831055|imex:IM-21659-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196233(gene)|ensembl:ENST00000356016(transcript)|ensembl:ENST00000371097(transcript)|ensembl:ENST00000371103(transcript)|ensembl:ENST00000675471(transcript)|ensembl:ENST00000675537(transcript)|ensembl:ENST00000675971(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|mint:Q96JN0|rcsb pdb:2COB|refseq:NP_001164236.1|refseq:NP_001164237.1|refseq:NP_115816.2|refseq:XP_016872275.1|refseq:XP_016872276.1|refseq:XP_016872277.1|refseq:NP_001333445.1|uniprotkb:Q8N655(identity)|entrezgene/locuslink:26148(identity)|ddbj/embl/genbank:BC024315(identity) dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:Q15022(identity)|entrezgene/locuslink:23512(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:cOnk6EDDff86yaG1uG+dxEQ1Z689606 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 intact-crc:166C7796C9D508AA|rigid:AhX6sgxazM46UXGfCtleMilCMAY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JN0 uniprotkb:Q5T6S3 intact:EBI-746045|uniprotkb:Q9H945|uniprotkb:Q9Y457|ensembl:ENSP00000348298|ensembl:ENSP00000360138|ensembl:ENSP00000360144|ensembl:ENSP00000501560|ensembl:ENSP00000501639|ensembl:ENSP00000502633|intact:EBI-8833163|uniprotkb:D3DR47|uniprotkb:Q5VW16|uniprotkb:Q7Z723|uniprotkb:Q86T32|uniprotkb:Q86T33|uniprotkb:Q8N3L6|uniprotkb:Q8N655 intact:EBI-2339674|uniprotkb:Q6N038|uniprotkb:Q32NF2|uniprotkb:Q8TBL6|uniprotkb:Q5T6S4|uniprotkb:Q9UFS9|ensembl:ENSP00000363003 psi-mi:lcor_human(display_long)|uniprotkb:LCOR(gene name)|psi-mi:LCOR(display_short)|uniprotkb:C10orf12(gene name synonym)|uniprotkb:KIAA1795(gene name synonym)|uniprotkb:MLR2(gene name synonym)|uniprotkb:Mblk1-related protein 2(gene name synonym) psi-mi:phf19_human(display_long)|uniprotkb:PHF19(gene name)|psi-mi:PHF19(display_short)|uniprotkb:PCL3(gene name synonym)|uniprotkb:Polycomb-like protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831055|imex:IM-21659-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196233(gene)|ensembl:ENST00000356016(transcript)|ensembl:ENST00000371097(transcript)|ensembl:ENST00000371103(transcript)|ensembl:ENST00000675471(transcript)|ensembl:ENST00000675537(transcript)|ensembl:ENST00000675971(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|mint:Q96JN0|rcsb pdb:2COB|refseq:NP_001164236.1|refseq:NP_001164237.1|refseq:NP_115816.2|refseq:XP_016872275.1|refseq:XP_016872276.1|refseq:XP_016872277.1|refseq:NP_001333445.1|uniprotkb:Q8N655(identity)|entrezgene/locuslink:26148(identity)|ddbj/embl/genbank:BC024315(identity) refseq:XP_011516811.1|refseq:NP_001009936.1|refseq:NP_056466.1|refseq:NP_001273769.1|refseq:NP_001273772.1|refseq:XP_005251963.1|refseq:XP_016870101.1|ensembl:ENSG00000119403(gene)|ensembl:ENST00000373896(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042017|mint:Q5T6S3|rcsb pdb:2E5Q|rcsb pdb:4BD3|rcsb pdb:6NQ3|rcsb pdb:6WAU|reactome:R-HSA-212300|uniprotkb:Q5T6S3(identity)|entrezgene/locuslink:26147(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:cOnk6EDDff86yaG1uG+dxEQ1Z689606 rogid:K4sKpUT1htSiigJaEoGyDjvkWqc9606 intact-crc:166C7796C9D508AA|rigid:AhX6sgxazM46UXGfCtleMilCMAY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JN0 uniprotkb:Q92800 intact:EBI-746045|uniprotkb:Q9H945|uniprotkb:Q9Y457|ensembl:ENSP00000348298|ensembl:ENSP00000360138|ensembl:ENSP00000360144|ensembl:ENSP00000501560|ensembl:ENSP00000501639|ensembl:ENSP00000502633|intact:EBI-8833163|uniprotkb:D3DR47|uniprotkb:Q5VW16|uniprotkb:Q7Z723|uniprotkb:Q86T32|uniprotkb:Q86T33|uniprotkb:Q8N3L6|uniprotkb:Q8N655 intact:EBI-8830732|uniprotkb:B4E3R7|uniprotkb:O43287|uniprotkb:A6NCH6|uniprotkb:Q14459|uniprotkb:Q53XP3|uniprotkb:B4DSS2|uniprotkb:B4DIJ1|uniprotkb:B4DIZ7|ensembl:ENSP00000404658|ensembl:ENSP00000466924 psi-mi:lcor_human(display_long)|uniprotkb:LCOR(gene name)|psi-mi:LCOR(display_short)|uniprotkb:C10orf12(gene name synonym)|uniprotkb:KIAA1795(gene name synonym)|uniprotkb:MLR2(gene name synonym)|uniprotkb:Mblk1-related protein 2(gene name synonym) psi-mi:ezh1_human(display_long)|uniprotkb:ENX-2(gene name synonym)|uniprotkb:Enhancer of zeste homolog 1(gene name synonym)|uniprotkb:KIAA0388(gene name synonym)|uniprotkb:EZH1(gene name)|psi-mi:EZH1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831055|imex:IM-21659-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196233(gene)|ensembl:ENST00000356016(transcript)|ensembl:ENST00000371097(transcript)|ensembl:ENST00000371103(transcript)|ensembl:ENST00000675471(transcript)|ensembl:ENST00000675537(transcript)|ensembl:ENST00000675971(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|mint:Q96JN0|rcsb pdb:2COB|refseq:NP_001164236.1|refseq:NP_001164237.1|refseq:NP_115816.2|refseq:XP_016872275.1|refseq:XP_016872276.1|refseq:XP_016872277.1|refseq:NP_001333445.1|uniprotkb:Q8N655(identity)|entrezgene/locuslink:26148(identity)|ddbj/embl/genbank:BC024315(identity) refseq:NP_001308008.1|refseq:NP_001308010.1|refseq:NP_001308011.1|refseq:NP_001982.2|dip:DIP-58580N|ensembl:ENSG00000108799(gene)|ensembl:ENST00000428826(transcript)|ensembl:ENST00000592743(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0021766"(hippocampus development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0031507"(heterochromatin assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR021654|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR032926|interpro:IPR041343|interpro:IPR041355|interpro:IPR044438|mint:Q92800|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|uniprotkb:Q92800(identity)|entrezgene/locuslink:2145(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:cOnk6EDDff86yaG1uG+dxEQ1Z689606 rogid:qp3eqBCgiaoA6VSSyqpW1d9YKN49606 intact-crc:166C7796C9D508AA|rigid:AhX6sgxazM46UXGfCtleMilCMAY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JN0 uniprotkb:Q09028 intact:EBI-746045|uniprotkb:Q9H945|uniprotkb:Q9Y457|ensembl:ENSP00000348298|ensembl:ENSP00000360138|ensembl:ENSP00000360144|ensembl:ENSP00000501560|ensembl:ENSP00000501639|ensembl:ENSP00000502633|intact:EBI-8833163|uniprotkb:D3DR47|uniprotkb:Q5VW16|uniprotkb:Q7Z723|uniprotkb:Q86T32|uniprotkb:Q86T33|uniprotkb:Q8N3L6|uniprotkb:Q8N655 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 psi-mi:lcor_human(display_long)|uniprotkb:LCOR(gene name)|psi-mi:LCOR(display_short)|uniprotkb:C10orf12(gene name synonym)|uniprotkb:KIAA1795(gene name synonym)|uniprotkb:MLR2(gene name synonym)|uniprotkb:Mblk1-related protein 2(gene name synonym) psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831055|imex:IM-21659-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196233(gene)|ensembl:ENST00000356016(transcript)|ensembl:ENST00000371097(transcript)|ensembl:ENST00000371103(transcript)|ensembl:ENST00000675471(transcript)|ensembl:ENST00000675537(transcript)|ensembl:ENST00000675971(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|mint:Q96JN0|rcsb pdb:2COB|refseq:NP_001164236.1|refseq:NP_001164237.1|refseq:NP_115816.2|refseq:XP_016872275.1|refseq:XP_016872276.1|refseq:XP_016872277.1|refseq:NP_001333445.1|uniprotkb:Q8N655(identity)|entrezgene/locuslink:26148(identity)|ddbj/embl/genbank:BC024315(identity) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|entrezgene/locuslink:5928(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:cOnk6EDDff86yaG1uG+dxEQ1Z689606 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 intact-crc:166C7796C9D508AA|rigid:AhX6sgxazM46UXGfCtleMilCMAY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JN0 uniprotkb:Q16576 intact:EBI-746045|uniprotkb:Q9H945|uniprotkb:Q9Y457|ensembl:ENSP00000348298|ensembl:ENSP00000360138|ensembl:ENSP00000360144|ensembl:ENSP00000501560|ensembl:ENSP00000501639|ensembl:ENSP00000502633|intact:EBI-8833163|uniprotkb:D3DR47|uniprotkb:Q5VW16|uniprotkb:Q7Z723|uniprotkb:Q86T32|uniprotkb:Q86T33|uniprotkb:Q8N3L6|uniprotkb:Q8N655 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 psi-mi:lcor_human(display_long)|uniprotkb:LCOR(gene name)|psi-mi:LCOR(display_short)|uniprotkb:C10orf12(gene name synonym)|uniprotkb:KIAA1795(gene name synonym)|uniprotkb:MLR2(gene name synonym)|uniprotkb:Mblk1-related protein 2(gene name synonym) psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831055|imex:IM-21659-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196233(gene)|ensembl:ENST00000356016(transcript)|ensembl:ENST00000371097(transcript)|ensembl:ENST00000371103(transcript)|ensembl:ENST00000675471(transcript)|ensembl:ENST00000675537(transcript)|ensembl:ENST00000675971(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|mint:Q96JN0|rcsb pdb:2COB|refseq:NP_001164236.1|refseq:NP_001164237.1|refseq:NP_115816.2|refseq:XP_016872275.1|refseq:XP_016872276.1|refseq:XP_016872277.1|refseq:NP_001333445.1|uniprotkb:Q8N655(identity)|entrezgene/locuslink:26148(identity)|ddbj/embl/genbank:BC024315(identity) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|entrezgene/locuslink:5931(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:cOnk6EDDff86yaG1uG+dxEQ1Z689606 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 intact-crc:166C7796C9D508AA|rigid:AhX6sgxazM46UXGfCtleMilCMAY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6NHQ4 uniprotkb:Q13618 intact:EBI-8831125|ensembl:ENSP00000483859|ensembl:ENSP00000484710 intact:EBI-456129|uniprotkb:O75415|uniprotkb:Q569L3|uniprotkb:Q9UBI8|uniprotkb:B8ZZC3|uniprotkb:Q9UET7|uniprotkb:A8K536|ensembl:ENSP00000264414 psi-mi:epop_human(display_long)|uniprotkb:EPOP(gene name)|psi-mi:EPOP(display_short)|uniprotkb:C17orf96(gene name synonym)|uniprotkb:PRR28(gene name synonym)|uniprotkb:Proline-rich protein 28(gene name synonym) psi-mi:cul3_human(display_long)|uniprotkb:CUL3(gene name)|psi-mi:CUL3(display_short)|uniprotkb:KIAA0617(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831129|imex:IM-21659-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124149.1|ensembl:ENSG00000273604(gene)|ensembl:ENST00000613024(transcript)|ensembl:ENST00000621654(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005694"(chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0070449"(elongin complex)|interpro:IPR027971|mint:A6NHQ4|ensembl:ENSG00000277303(gene)|uniprotkb:A6NHQ4(identity)|entrezgene/locuslink:100170841(identity) refseq:NP_003581.1|refseq:NP_001244126.1|refseq:NP_001244127.1|dip:DIP-31611N|ensembl:ENSG00000036257(gene)|ensembl:ENST00000264414(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000922"(spindle pole)|go:"GO:0001831"(trophectodermal cellular morphogenesis)|go:"GO:0005112"(Notch binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005827"(polar microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007369"(gastrulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017145"(stem cell division)|go:"GO:0030030"(cell projection organization)|go:"GO:0030332"(cyclin binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031208"(POZ domain binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042802"(identical protein binding)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044346"(fibroblast apoptotic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071630"(nuclear protein quality control by the ubiquitin-proteasome system)|go:"GO:0072576"(liver morphogenesis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1901992"(positive regulation of mitotic cell cycle phase transition)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13618|rcsb pdb:2MYL|rcsb pdb:2MYM|rcsb pdb:4AP2|rcsb pdb:4APF|rcsb pdb:4EOZ|rcsb pdb:4HXI|rcsb pdb:5NLB|rcsb pdb:6I2M|reactome:R-HSA-4641258|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-8932339|reactome:R-HSA-8951664|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-9706019|reactome:R-HSA-983168|uniprotkb:Q13618(identity)|entrezgene/locuslink:8452(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:xxrapCjRxgY22pLac2F4zSS2bvk9606 rogid:xI/8pHB9nckOW629STOqKba4KzQ9606 intact-crc:644AA84D342D0070|rigid:25HowGg7RehzXypa3AvPtYe58BQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6NHQ4 uniprotkb:Q12873 intact:EBI-8831125|ensembl:ENSP00000483859|ensembl:ENSP00000484710 intact:EBI-523590|uniprotkb:Q9Y4I0|intact:EBI-28978117|ensembl:ENSP00000332628|uniprotkb:D3DTQ9|uniprotkb:E9PG89 psi-mi:epop_human(display_long)|uniprotkb:EPOP(gene name)|psi-mi:EPOP(display_short)|uniprotkb:C17orf96(gene name synonym)|uniprotkb:PRR28(gene name synonym)|uniprotkb:Proline-rich protein 28(gene name synonym) psi-mi:chd3_human(display_long)|uniprotkb:ATP-dependent helicase CHD3(gene name synonym)|uniprotkb:Mi-2 autoantigen 240 kDa protein(gene name synonym)|uniprotkb:Mi2-alpha(gene name synonym)|uniprotkb:Zinc finger helicase(gene name synonym)|uniprotkb:CHD3(gene name)|psi-mi:CHD3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831129|imex:IM-21659-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124149.1|ensembl:ENSG00000273604(gene)|ensembl:ENST00000613024(transcript)|ensembl:ENST00000621654(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005694"(chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0070449"(elongin complex)|interpro:IPR027971|mint:A6NHQ4|ensembl:ENSG00000277303(gene)|uniprotkb:A6NHQ4(identity)|entrezgene/locuslink:100170841(identity) interpro:IPR023780|interpro:IPR027417|interpro:IPR036910|interpro:IPR038718|mint:Q12873|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-4551638|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|ensembl:ENSG00000170004(gene)|ensembl:ENST00000330494(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007051"(spindle organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0016605"(PML body)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036121"(double-stranded DNA helicase activity)|go:"GO:0043044"|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|go:"GO:0070615"|interpro:IPR019787|interpro:IPR023779|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|ensembl:ENSP00000332628|ensembl:ENST00000358181|ensembl:ENSP00000350907|ensembl:ENST00000380358|ensembl:ENSP00000369716|refseq:NP_001005271.2|refseq:NP_001005273.1|refseq:NP_005843.2|dip:DIP-32496N|uniprotkb:Q12873(identity)|entrezgene/locuslink:1107(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:xxrapCjRxgY22pLac2F4zSS2bvk9606 rogid:UjefFUXiV28qhOP9BoIUansxl+k9606 intact-crc:644AA84D342D0070|rigid:25HowGg7RehzXypa3AvPtYe58BQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6NHQ4 uniprotkb:O75530 intact:EBI-8831125|ensembl:ENSP00000483859|ensembl:ENSP00000484710 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 psi-mi:epop_human(display_long)|uniprotkb:EPOP(gene name)|psi-mi:EPOP(display_short)|uniprotkb:C17orf96(gene name synonym)|uniprotkb:PRR28(gene name synonym)|uniprotkb:Proline-rich protein 28(gene name synonym) psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831129|imex:IM-21659-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124149.1|ensembl:ENSG00000273604(gene)|ensembl:ENST00000613024(transcript)|ensembl:ENST00000621654(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005694"(chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0070449"(elongin complex)|interpro:IPR027971|mint:A6NHQ4|ensembl:ENSG00000277303(gene)|uniprotkb:A6NHQ4(identity)|entrezgene/locuslink:100170841(identity) refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:O75530(identity)|entrezgene/locuslink:8726(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:xxrapCjRxgY22pLac2F4zSS2bvk9606 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 intact-crc:644AA84D342D0070|rigid:25HowGg7RehzXypa3AvPtYe58BQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6NHQ4 uniprotkb:Q92800 intact:EBI-8831125|ensembl:ENSP00000483859|ensembl:ENSP00000484710 intact:EBI-8830732|uniprotkb:B4E3R7|uniprotkb:O43287|uniprotkb:A6NCH6|uniprotkb:Q14459|uniprotkb:Q53XP3|uniprotkb:B4DSS2|uniprotkb:B4DIJ1|uniprotkb:B4DIZ7|ensembl:ENSP00000404658|ensembl:ENSP00000466924 psi-mi:epop_human(display_long)|uniprotkb:EPOP(gene name)|psi-mi:EPOP(display_short)|uniprotkb:C17orf96(gene name synonym)|uniprotkb:PRR28(gene name synonym)|uniprotkb:Proline-rich protein 28(gene name synonym) psi-mi:ezh1_human(display_long)|uniprotkb:ENX-2(gene name synonym)|uniprotkb:Enhancer of zeste homolog 1(gene name synonym)|uniprotkb:KIAA0388(gene name synonym)|uniprotkb:EZH1(gene name)|psi-mi:EZH1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831129|imex:IM-21659-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124149.1|ensembl:ENSG00000273604(gene)|ensembl:ENST00000613024(transcript)|ensembl:ENST00000621654(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005694"(chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0070449"(elongin complex)|interpro:IPR027971|mint:A6NHQ4|ensembl:ENSG00000277303(gene)|uniprotkb:A6NHQ4(identity)|entrezgene/locuslink:100170841(identity) refseq:NP_001308008.1|refseq:NP_001308010.1|refseq:NP_001308011.1|refseq:NP_001982.2|dip:DIP-58580N|ensembl:ENSG00000108799(gene)|ensembl:ENST00000428826(transcript)|ensembl:ENST00000592743(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0021766"(hippocampus development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0031507"(heterochromatin assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR021654|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR032926|interpro:IPR041343|interpro:IPR041355|interpro:IPR044438|mint:Q92800|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|uniprotkb:Q92800(identity)|entrezgene/locuslink:2145(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:xxrapCjRxgY22pLac2F4zSS2bvk9606 rogid:qp3eqBCgiaoA6VSSyqpW1d9YKN49606 intact-crc:644AA84D342D0070|rigid:25HowGg7RehzXypa3AvPtYe58BQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6NHQ4 uniprotkb:Q15022 intact:EBI-8831125|ensembl:ENSP00000483859|ensembl:ENSP00000484710 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 psi-mi:epop_human(display_long)|uniprotkb:EPOP(gene name)|psi-mi:EPOP(display_short)|uniprotkb:C17orf96(gene name synonym)|uniprotkb:PRR28(gene name synonym)|uniprotkb:Proline-rich protein 28(gene name synonym) psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831129|imex:IM-21659-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124149.1|ensembl:ENSG00000273604(gene)|ensembl:ENST00000613024(transcript)|ensembl:ENST00000621654(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005694"(chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0070449"(elongin complex)|interpro:IPR027971|mint:A6NHQ4|ensembl:ENSG00000277303(gene)|uniprotkb:A6NHQ4(identity)|entrezgene/locuslink:100170841(identity) dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:Q15022(identity)|entrezgene/locuslink:23512(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:xxrapCjRxgY22pLac2F4zSS2bvk9606 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 intact-crc:644AA84D342D0070|rigid:25HowGg7RehzXypa3AvPtYe58BQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6NHQ4 uniprotkb:O14929 intact:EBI-8831125|ensembl:ENSP00000483859|ensembl:ENSP00000484710 intact:EBI-2339359|uniprotkb:Q53SU4|uniprotkb:Q53QF0|uniprotkb:Q49A44|uniprotkb:Q6P594|uniprotkb:Q8WWB9|ensembl:ENSP00000264108 psi-mi:epop_human(display_long)|uniprotkb:EPOP(gene name)|psi-mi:EPOP(display_short)|uniprotkb:C17orf96(gene name synonym)|uniprotkb:PRR28(gene name synonym)|uniprotkb:Proline-rich protein 28(gene name synonym) psi-mi:hat1_human(display_long)|uniprotkb:HAT1(gene name)|psi-mi:HAT1(display_short)|uniprotkb:KAT1(gene name synonym)|uniprotkb:Histone acetyltransferase 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831129|imex:IM-21659-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124149.1|ensembl:ENSG00000273604(gene)|ensembl:ENST00000613024(transcript)|ensembl:ENST00000621654(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005694"(chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0070449"(elongin complex)|interpro:IPR027971|mint:A6NHQ4|ensembl:ENSG00000277303(gene)|uniprotkb:A6NHQ4(identity)|entrezgene/locuslink:100170841(identity) refseq:NP_003633.1|dip:DIP-52811N|ensembl:ENSG00000128708(gene)|ensembl:ENST00000264108(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006323"(DNA packaging)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006348"|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0007584"(response to nutrient)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR013523(Histone acetyltransferase HAT1, C-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017380(Histone acetyltransferase type B, catalytic subunit)|interpro:IPR019467|interpro:IPR037113|mint:O14929|rcsb pdb:2P0W|rcsb pdb:6VO5|reactome:R-HSA-3214847|uniprotkb:O14929(identity)|entrezgene/locuslink:8520(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:xxrapCjRxgY22pLac2F4zSS2bvk9606 rogid:80KgRaid3NeRfAUdTHMQ/r0VuGo9606 intact-crc:644AA84D342D0070|rigid:25HowGg7RehzXypa3AvPtYe58BQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6NHQ4 uniprotkb:Q09028 intact:EBI-8831125|ensembl:ENSP00000483859|ensembl:ENSP00000484710 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 psi-mi:epop_human(display_long)|uniprotkb:EPOP(gene name)|psi-mi:EPOP(display_short)|uniprotkb:C17orf96(gene name synonym)|uniprotkb:PRR28(gene name synonym)|uniprotkb:Proline-rich protein 28(gene name synonym) psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831129|imex:IM-21659-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124149.1|ensembl:ENSG00000273604(gene)|ensembl:ENST00000613024(transcript)|ensembl:ENST00000621654(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005694"(chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0070449"(elongin complex)|interpro:IPR027971|mint:A6NHQ4|ensembl:ENSG00000277303(gene)|uniprotkb:A6NHQ4(identity)|entrezgene/locuslink:100170841(identity) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|entrezgene/locuslink:5928(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:xxrapCjRxgY22pLac2F4zSS2bvk9606 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 intact-crc:644AA84D342D0070|rigid:25HowGg7RehzXypa3AvPtYe58BQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6NHQ4 uniprotkb:Q15369 intact:EBI-8831125|ensembl:ENSP00000483859|ensembl:ENSP00000484710 intact:EBI-301231|uniprotkb:Q567Q6|ensembl:ENSP00000284811|ensembl:ENSP00000428074|ensembl:ENSP00000428171|ensembl:ENSP00000428334|ensembl:ENSP00000429596|ensembl:ENSP00000429906|ensembl:ENSP00000478121|uniprotkb:E5RGD9 psi-mi:epop_human(display_long)|uniprotkb:EPOP(gene name)|psi-mi:EPOP(display_short)|uniprotkb:C17orf96(gene name synonym)|uniprotkb:PRR28(gene name synonym)|uniprotkb:Proline-rich protein 28(gene name synonym) psi-mi:eloc_human(display_long)|uniprotkb:ELOC(gene name)|psi-mi:ELOC(display_short)|uniprotkb:Elongin 15 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit C(gene name synonym)|uniprotkb:SIII p15(gene name synonym)|uniprotkb:TCEB1(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831129|imex:IM-21659-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124149.1|ensembl:ENSG00000273604(gene)|ensembl:ENST00000613024(transcript)|ensembl:ENST00000621654(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005694"(chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0070449"(elongin complex)|interpro:IPR027971|mint:A6NHQ4|ensembl:ENSG00000277303(gene)|uniprotkb:A6NHQ4(identity)|entrezgene/locuslink:100170841(identity) refseq:NP_005639.1|refseq:NP_001191786.1|refseq:NP_001191787.1|refseq:NP_001191788.1|refseq:NP_001191789.1|refseq:NP_001191790.1|refseq:NP_001191791.1|refseq:NP_001191792.1|refseq:NP_001191793.1|ensembl:ENSG00000154582(gene)|ensembl:ENST00000284811(transcript)|ensembl:ENST00000518127(transcript)|ensembl:ENST00000519487(transcript)|ensembl:ENST00000520242(transcript)|ensembl:ENST00000522337(transcript)|ensembl:ENST00000523815(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0070449"(elongin complex)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|mint:Q15369|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|ensembl:ENST00000622804(transcript)|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:4WQO|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:6HAX|rcsb pdb:6GFY|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7N|rcsb pdb:6SIS|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-167200|refseq:XP_011515882.1|refseq:XP_011515883.1|dip:DIP-29571N|uniprotkb:Q15369(identity)|entrezgene/locuslink:6921(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:xxrapCjRxgY22pLac2F4zSS2bvk9606 rogid:Ngvkh3YoddZoutF3Vgwdi2b6xz49606 intact-crc:644AA84D342D0070|rigid:25HowGg7RehzXypa3AvPtYe58BQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6NHQ4 uniprotkb:Q9Y483 intact:EBI-8831125|ensembl:ENSP00000483859|ensembl:ENSP00000484710 intact:EBI-725816|uniprotkb:A6NGQ9|uniprotkb:Q9UES9|uniprotkb:Q9UP40|uniprotkb:A8K2Q3|uniprotkb:B1AKT5|intact:EBI-11028207|uniprotkb:Q96G26|uniprotkb:B1AKT6|ensembl:ENSP00000359321 psi-mi:epop_human(display_long)|uniprotkb:EPOP(gene name)|psi-mi:EPOP(display_short)|uniprotkb:C17orf96(gene name synonym)|uniprotkb:PRR28(gene name synonym)|uniprotkb:Proline-rich protein 28(gene name synonym) psi-mi:mtf2_human(display_long)|uniprotkb:PCL2(gene name synonym)|uniprotkb:Metal-response element DNA-binding protein M96(gene name synonym)|uniprotkb:Metal regulatory transcription factor 2(gene name synonym)|uniprotkb:Polycomb-like protein 2(gene name synonym)|uniprotkb:MTF2(gene name)|psi-mi:MTF2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831129|imex:IM-21659-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124149.1|ensembl:ENSG00000273604(gene)|ensembl:ENST00000613024(transcript)|ensembl:ENST00000621654(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005694"(chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0070449"(elongin complex)|interpro:IPR027971|mint:A6NHQ4|ensembl:ENSG00000277303(gene)|uniprotkb:A6NHQ4(identity)|entrezgene/locuslink:100170841(identity) refseq:NP_001157863.1|refseq:NP_001157865.1|refseq:NP_031384.1|refseq:XP_011539318.1|refseq:XP_016856165.1|ensembl:ENSG00000143033(gene)|ensembl:ENST00000370298(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042015|mint:Q9Y483|rcsb pdb:5XFR|reactome:R-HSA-212300|interpro:IPR042014|refseq:NP_001157864.1|uniprotkb:Q9Y483(identity)|entrezgene/locuslink:22823(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:xxrapCjRxgY22pLac2F4zSS2bvk9606 rogid:Im8E6U/OPb8AEir43AUUDlU6F2o9606 intact-crc:644AA84D342D0070|rigid:25HowGg7RehzXypa3AvPtYe58BQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6NHQ4 uniprotkb:Q15370 intact:EBI-8831125|ensembl:ENSP00000483859|ensembl:ENSP00000484710 intact:EBI-301238|ensembl:ENSP00000386652|uniprotkb:B7WPD3 psi-mi:epop_human(display_long)|uniprotkb:EPOP(gene name)|psi-mi:EPOP(display_short)|uniprotkb:C17orf96(gene name synonym)|uniprotkb:PRR28(gene name synonym)|uniprotkb:Proline-rich protein 28(gene name synonym) psi-mi:elob_human(display_long)|uniprotkb:ELOB(gene name)|psi-mi:ELOB(display_short)|uniprotkb:Elongin 18 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit B(gene name synonym)|uniprotkb:SIII p18(gene name synonym)|uniprotkb:TCEB2(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831129|imex:IM-21659-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124149.1|ensembl:ENSG00000273604(gene)|ensembl:ENST00000613024(transcript)|ensembl:ENST00000621654(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005694"(chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0070449"(elongin complex)|interpro:IPR027971|mint:A6NHQ4|ensembl:ENSG00000277303(gene)|uniprotkb:A6NHQ4(identity)|entrezgene/locuslink:100170841(identity) ensembl:ENSG00000103363(gene)|ensembl:ENST00000409906(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030891"(VCB complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070449"(elongin complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR039049|mint:Q15370|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2JZ3|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFY|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:4WQO|rcsb pdb:6HAX|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:6SIS|refseq:NP_009039.1|refseq:NP_996896.1|dip:DIP-29570N|uniprotkb:Q15370(identity)|entrezgene/locuslink:6923(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:xxrapCjRxgY22pLac2F4zSS2bvk9606 rogid:apX4QFpDC4Dz3MAs7tQ8+XFHx6I9606 intact-crc:644AA84D342D0070|rigid:25HowGg7RehzXypa3AvPtYe58BQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6NHQ4 uniprotkb:Q96M94 intact:EBI-8831125|ensembl:ENSP00000483859|ensembl:ENSP00000484710 intact:EBI-2510129|ensembl:ENSP00000332791|uniprotkb:Q9C0I6|uniprotkb:Q32MN3|uniprotkb:Q96BM6|uniprotkb:Q8NDA3 psi-mi:epop_human(display_long)|uniprotkb:EPOP(gene name)|psi-mi:EPOP(display_short)|uniprotkb:C17orf96(gene name synonym)|uniprotkb:PRR28(gene name synonym)|uniprotkb:Proline-rich protein 28(gene name synonym) psi-mi:klh15_human(display_long)|uniprotkb:KLHL15(gene name)|psi-mi:KLHL15(display_short)|uniprotkb:KIAA1677(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831129|imex:IM-21659-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124149.1|ensembl:ENSG00000273604(gene)|ensembl:ENST00000613024(transcript)|ensembl:ENST00000621654(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005694"(chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0070449"(elongin complex)|interpro:IPR027971|mint:A6NHQ4|ensembl:ENSG00000277303(gene)|uniprotkb:A6NHQ4(identity)|entrezgene/locuslink:100170841(identity) ensembl:ENSG00000174010(gene)|ensembl:ENST00000328046(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0071630"(nuclear protein quality control by the ubiquitin-proteasome system)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030597|refseq:NP_085127.2|refseq:XP_006724581.1|uniprotkb:Q96M94(identity)|entrezgene/locuslink:80311(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:xxrapCjRxgY22pLac2F4zSS2bvk9606 rogid:Xkm72585iSVnSMqN1b0XM79Pd2g9606 intact-crc:644AA84D342D0070|rigid:25HowGg7RehzXypa3AvPtYe58BQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6NHQ4 uniprotkb:O43189 intact:EBI-8831125|ensembl:ENSP00000483859|ensembl:ENSP00000484710 intact:EBI-530034|uniprotkb:B1AZX2|uniprotkb:B1AZX3|uniprotkb:O60929|uniprotkb:Q96KM7|uniprotkb:Q5SU07|uniprotkb:Q5SU08|ensembl:ENSP00000363640|ensembl:ENSP00000391901|ensembl:ENSP00000407295 psi-mi:epop_human(display_long)|uniprotkb:EPOP(gene name)|psi-mi:EPOP(display_short)|uniprotkb:C17orf96(gene name synonym)|uniprotkb:PRR28(gene name synonym)|uniprotkb:Proline-rich protein 28(gene name synonym) psi-mi:phf1_human(display_long)|uniprotkb:PCL1(gene name synonym)|uniprotkb:Polycomb-like protein 1(gene name synonym)|uniprotkb:PHF1(gene name)|psi-mi:PHF1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831129|imex:IM-21659-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124149.1|ensembl:ENSG00000273604(gene)|ensembl:ENST00000613024(transcript)|ensembl:ENST00000621654(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005694"(chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0070449"(elongin complex)|interpro:IPR027971|mint:A6NHQ4|ensembl:ENSG00000277303(gene)|uniprotkb:A6NHQ4(identity)|entrezgene/locuslink:100170841(identity) refseq:XP_011512964.1|refseq:NP_002627.1|refseq:NP_077084.1|ensembl:ENSG00000112511(gene)|ensembl:ENSG00000225553(gene)|ensembl:ENST00000374516(transcript)|ensembl:ENST00000427869(transcript)|ensembl:ENST00000454914(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR031202|interpro:IPR040477|mint:O43189|rcsb pdb:2E5P|rcsb pdb:2M0O|rcsb pdb:4HCZ|rcsb pdb:5XFN|rcsb pdb:5XFO|rcsb pdb:5XFP|rcsb pdb:6WAT|rcsb pdb:6WAV|reactome:R-HSA-212300|dip:DIP-34001N|uniprotkb:O43189(identity)|entrezgene/locuslink:5252(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:xxrapCjRxgY22pLac2F4zSS2bvk9606 rogid:8n8g2LqzuOQb8cFC7tE1j/xBvkI9606 intact-crc:644AA84D342D0070|rigid:25HowGg7RehzXypa3AvPtYe58BQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6NHQ4 uniprotkb:Q15910 intact:EBI-8831125|ensembl:ENSP00000483859|ensembl:ENSP00000484710 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 psi-mi:epop_human(display_long)|uniprotkb:EPOP(gene name)|psi-mi:EPOP(display_short)|uniprotkb:C17orf96(gene name synonym)|uniprotkb:PRR28(gene name synonym)|uniprotkb:Proline-rich protein 28(gene name synonym) psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831129|imex:IM-21659-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124149.1|ensembl:ENSG00000273604(gene)|ensembl:ENST00000613024(transcript)|ensembl:ENST00000621654(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005694"(chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0070449"(elongin complex)|interpro:IPR027971|mint:A6NHQ4|ensembl:ENSG00000277303(gene)|uniprotkb:A6NHQ4(identity)|entrezgene/locuslink:100170841(identity) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N|uniprotkb:Q15910(identity)|entrezgene/locuslink:2146(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:xxrapCjRxgY22pLac2F4zSS2bvk9606 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 intact-crc:644AA84D342D0070|rigid:25HowGg7RehzXypa3AvPtYe58BQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6NHQ4 uniprotkb:Q92769 intact:EBI-8831125|ensembl:ENSP00000483859|ensembl:ENSP00000484710 intact:EBI-301821|uniprotkb:Q5SRI8|uniprotkb:Q5SZ86|uniprotkb:Q8NEH4|uniprotkb:B4DL58|ensembl:ENSP00000430432|uniprotkb:E1P561|uniprotkb:B3KRS5 psi-mi:epop_human(display_long)|uniprotkb:EPOP(gene name)|psi-mi:EPOP(display_short)|uniprotkb:C17orf96(gene name synonym)|uniprotkb:PRR28(gene name synonym)|uniprotkb:Proline-rich protein 28(gene name synonym) psi-mi:hdac2_human(display_long)|uniprotkb:HDAC2(gene name)|psi-mi:HDAC2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831129|imex:IM-21659-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124149.1|ensembl:ENSG00000273604(gene)|ensembl:ENST00000613024(transcript)|ensembl:ENST00000621654(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005694"(chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0070449"(elongin complex)|interpro:IPR027971|mint:A6NHQ4|ensembl:ENSG00000277303(gene)|uniprotkb:A6NHQ4(identity)|entrezgene/locuslink:100170841(identity) go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035094"(response to nicotine)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042220"(response to cocaine)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q92769|rcsb pdb:3MAX|rcsb pdb:4LXZ|rcsb pdb:4LY1|rcsb pdb:5IWG|rcsb pdb:5IX0|rcsb pdb:6G3O|rcsb pdb:6WBW|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000196591(gene)|ensembl:ENST00000519065(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|rcsb pdb:6WHN|rcsb pdb:6WHO|rcsb pdb:6WHQ|rcsb pdb:6WHZ|rcsb pdb:6WI3|rcsb pdb:6XDM|rcsb pdb:6XEB|rcsb pdb:6XEC|rcsb pdb:7KBG|rcsb pdb:7KBH|rcsb pdb:7LTG|rcsb pdb:7LTK|rcsb pdb:7LTL|reactome:R-HSA-193670|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9615017|reactome:R-HSA-9619665|reactome:R-HSA-9679191|reactome:R-HSA-983231|rcsb pdb:6WBZ|refseq:NP_001518.3|dip:DIP-24220N|refseq:XP_011534090.1|refseq:XP_016866288.1|uniprotkb:Q92769(identity)|entrezgene/locuslink:3066(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:xxrapCjRxgY22pLac2F4zSS2bvk9606 rogid:K4PpGz9E9/TrQZsgvrJuc+uYCn89606 intact-crc:644AA84D342D0070|rigid:25HowGg7RehzXypa3AvPtYe58BQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6NHQ4 uniprotkb:Q9BQE3 intact:EBI-8831125|ensembl:ENSP00000483859|ensembl:ENSP00000484710 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:epop_human(display_long)|uniprotkb:EPOP(gene name)|psi-mi:EPOP(display_short)|uniprotkb:C17orf96(gene name synonym)|uniprotkb:PRR28(gene name synonym)|uniprotkb:Proline-rich protein 28(gene name synonym) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831129|imex:IM-21659-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124149.1|ensembl:ENSG00000273604(gene)|ensembl:ENST00000613024(transcript)|ensembl:ENST00000621654(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005694"(chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0070449"(elongin complex)|interpro:IPR027971|mint:A6NHQ4|ensembl:ENSG00000277303(gene)|uniprotkb:A6NHQ4(identity)|entrezgene/locuslink:100170841(identity) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1|uniprotkb:Q9BQE3(identity)|entrezgene/locuslink:84790(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:xxrapCjRxgY22pLac2F4zSS2bvk9606 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:644AA84D342D0070|rigid:25HowGg7RehzXypa3AvPtYe58BQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6NHQ4 uniprotkb:Q15365 intact:EBI-8831125|ensembl:ENSP00000483859|ensembl:ENSP00000484710 intact:EBI-946095|uniprotkb:Q13157|uniprotkb:Q14975|ensembl:ENSP00000305556 psi-mi:epop_human(display_long)|uniprotkb:EPOP(gene name)|psi-mi:EPOP(display_short)|uniprotkb:C17orf96(gene name synonym)|uniprotkb:PRR28(gene name synonym)|uniprotkb:Proline-rich protein 28(gene name synonym) psi-mi:pcbp1_human(display_long)|uniprotkb:PCBP1(gene name)|psi-mi:PCBP1(display_short)|uniprotkb:Alpha-CP1(gene name synonym)|uniprotkb:Nucleic acid-binding protein SUB2.3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831129|imex:IM-21659-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124149.1|ensembl:ENSG00000273604(gene)|ensembl:ENST00000613024(transcript)|ensembl:ENST00000621654(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005694"(chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0070449"(elongin complex)|interpro:IPR027971|mint:A6NHQ4|ensembl:ENSG00000277303(gene)|uniprotkb:A6NHQ4(identity)|entrezgene/locuslink:100170841(identity) refseq:NP_006187.2|dip:DIP-38136N|ensembl:ENSG00000169564(gene)|ensembl:ENST00000303577(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098847"(sequence-specific single stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15365|rcsb pdb:1WVN|rcsb pdb:1ZTG|rcsb pdb:3VKE|reactome:R-HSA-72163|reactome:R-HSA-72203|uniprotkb:Q15365(identity)|entrezgene/locuslink:5093(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:xxrapCjRxgY22pLac2F4zSS2bvk9606 rogid:x72fawo4plQ+ipfqIoREIDHc2bA9606 intact-crc:644AA84D342D0070|rigid:25HowGg7RehzXypa3AvPtYe58BQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6NHQ4 uniprotkb:Q5T6S3 intact:EBI-8831125|ensembl:ENSP00000483859|ensembl:ENSP00000484710 intact:EBI-2339674|uniprotkb:Q6N038|uniprotkb:Q32NF2|uniprotkb:Q8TBL6|uniprotkb:Q5T6S4|uniprotkb:Q9UFS9|ensembl:ENSP00000363003 psi-mi:epop_human(display_long)|uniprotkb:EPOP(gene name)|psi-mi:EPOP(display_short)|uniprotkb:C17orf96(gene name synonym)|uniprotkb:PRR28(gene name synonym)|uniprotkb:Proline-rich protein 28(gene name synonym) psi-mi:phf19_human(display_long)|uniprotkb:PHF19(gene name)|psi-mi:PHF19(display_short)|uniprotkb:PCL3(gene name synonym)|uniprotkb:Polycomb-like protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831129|imex:IM-21659-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124149.1|ensembl:ENSG00000273604(gene)|ensembl:ENST00000613024(transcript)|ensembl:ENST00000621654(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005694"(chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0070449"(elongin complex)|interpro:IPR027971|mint:A6NHQ4|ensembl:ENSG00000277303(gene)|uniprotkb:A6NHQ4(identity)|entrezgene/locuslink:100170841(identity) refseq:XP_011516811.1|refseq:NP_001009936.1|refseq:NP_056466.1|refseq:NP_001273769.1|refseq:NP_001273772.1|refseq:XP_005251963.1|refseq:XP_016870101.1|ensembl:ENSG00000119403(gene)|ensembl:ENST00000373896(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042017|mint:Q5T6S3|rcsb pdb:2E5Q|rcsb pdb:4BD3|rcsb pdb:6NQ3|rcsb pdb:6WAU|reactome:R-HSA-212300|uniprotkb:Q5T6S3(identity)|entrezgene/locuslink:26147(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:xxrapCjRxgY22pLac2F4zSS2bvk9606 rogid:K4sKpUT1htSiigJaEoGyDjvkWqc9606 intact-crc:644AA84D342D0070|rigid:25HowGg7RehzXypa3AvPtYe58BQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6NHQ4 uniprotkb:P50990 intact:EBI-8831125|ensembl:ENSP00000483859|ensembl:ENSP00000484710 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:epop_human(display_long)|uniprotkb:EPOP(gene name)|psi-mi:EPOP(display_short)|uniprotkb:C17orf96(gene name synonym)|uniprotkb:PRR28(gene name synonym)|uniprotkb:Proline-rich protein 28(gene name synonym) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831129|imex:IM-21659-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124149.1|ensembl:ENSG00000273604(gene)|ensembl:ENST00000613024(transcript)|ensembl:ENST00000621654(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005694"(chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0070449"(elongin complex)|interpro:IPR027971|mint:A6NHQ4|ensembl:ENSG00000277303(gene)|uniprotkb:A6NHQ4(identity)|entrezgene/locuslink:100170841(identity) refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N|uniprotkb:P50990(identity)|entrezgene/locuslink:10694(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:xxrapCjRxgY22pLac2F4zSS2bvk9606 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 intact-crc:644AA84D342D0070|rigid:25HowGg7RehzXypa3AvPtYe58BQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6NHQ4 uniprotkb:Q16576 intact:EBI-8831125|ensembl:ENSP00000483859|ensembl:ENSP00000484710 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 psi-mi:epop_human(display_long)|uniprotkb:EPOP(gene name)|psi-mi:EPOP(display_short)|uniprotkb:C17orf96(gene name synonym)|uniprotkb:PRR28(gene name synonym)|uniprotkb:Proline-rich protein 28(gene name synonym) psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831129|imex:IM-21659-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124149.1|ensembl:ENSG00000273604(gene)|ensembl:ENST00000613024(transcript)|ensembl:ENST00000621654(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005694"(chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0070449"(elongin complex)|interpro:IPR027971|mint:A6NHQ4|ensembl:ENSG00000277303(gene)|uniprotkb:A6NHQ4(identity)|entrezgene/locuslink:100170841(identity) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|entrezgene/locuslink:5931(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:xxrapCjRxgY22pLac2F4zSS2bvk9606 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 intact-crc:644AA84D342D0070|rigid:25HowGg7RehzXypa3AvPtYe58BQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13112 uniprotkb:Q9Y266 intact:EBI-1052944|uniprotkb:Q99548|ensembl:ENSP00000315700 intact:EBI-357298|ensembl:ENSP00000319664|uniprotkb:Q5QP31|uniprotkb:Q5QP35|uniprotkb:Q9H0N2|uniprotkb:Q9Y2B6|intact:EBI-2555945 psi-mi:caf1b_human(display_long)|uniprotkb:Chromatin assembly factor I p60 subunit(gene name synonym)|uniprotkb:M-phase phosphoprotein 7(gene name synonym)|uniprotkb:CHAF1B(gene name)|psi-mi:CHAF1B(display_short)|uniprotkb:CAF1A(gene name synonym)|uniprotkb:CAF1P60(gene name synonym)|uniprotkb:MPHOSPH7(gene name synonym)|uniprotkb:MPP7(gene name synonym) psi-mi:nudc_human(display_long)|uniprotkb:NUDC(gene name)|psi-mi:NUDC(display_short)|uniprotkb:Nuclear distribution protein C homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831214|imex:IM-21659-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005432.1|dip:DIP-29243N|ensembl:ENSG00000159259(gene)|ensembl:ENST00000314103(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR029129|interpro:IPR036322|mint:Q13112|refseq:XP_016883966.1|refseq:XP_016883967.1|uniprotkb:Q13112(identity)|ddbj/embl/genbank:BC021218(identity)|entrezgene/locuslink:8208(identity) ensembl:ENSG00000090273(gene)|ensembl:ENST00000321265(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0030496"(midbody)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR025934|interpro:IPR032572|interpro:IPR037898|mint:Q9Y266|rcsb pdb:3QOR|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|go:"GO:0007080"(mitotic metaphase plate congression)|reactome:R-HSA-9696270|refseq:NP_006591.1|uniprotkb:Q9Y266(identity)|entrezgene/locuslink:10726(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:VVbW9mpUGYMRPxvlEk9FERHIsJs9606 rogid:e1Q+/+VhG73ljCc3+ibG+RZNQUM9606 intact-crc:026815AE27126A27|rigid:NgZwEzebNuoxrI25ak8BdL+tdCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13112 uniprotkb:Q13111 intact:EBI-1052944|uniprotkb:Q99548|ensembl:ENSP00000315700 intact:EBI-1020839|uniprotkb:Q7Z7K3|uniprotkb:Q9UJY8|uniprotkb:Q6NXG5|intact:EBI-28985893|ensembl:ENSP00000301280 psi-mi:caf1b_human(display_long)|uniprotkb:Chromatin assembly factor I p60 subunit(gene name synonym)|uniprotkb:M-phase phosphoprotein 7(gene name synonym)|uniprotkb:CHAF1B(gene name)|psi-mi:CHAF1B(display_short)|uniprotkb:CAF1A(gene name synonym)|uniprotkb:CAF1P60(gene name synonym)|uniprotkb:MPHOSPH7(gene name synonym)|uniprotkb:MPP7(gene name synonym) psi-mi:caf1a_human(display_long)|uniprotkb:CHAF1A(gene name)|psi-mi:CHAF1A(display_short)|uniprotkb:CAF(gene name synonym)|uniprotkb:CAF1P150(gene name synonym)|uniprotkb:Chromatin assembly factor I p150 subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831214|imex:IM-21659-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005432.1|dip:DIP-29243N|ensembl:ENSG00000159259(gene)|ensembl:ENST00000314103(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR029129|interpro:IPR036322|mint:Q13112|refseq:XP_016883966.1|refseq:XP_016883967.1|uniprotkb:Q13112(identity)|ddbj/embl/genbank:BC021218(identity)|entrezgene/locuslink:8208(identity) refseq:NP_005474.2|ensembl:ENSG00000167670(gene)|ensembl:ENST00000301280(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070087"(chromo shadow domain binding)|interpro:IPR022043|interpro:IPR029091|interpro:IPR029105|mint:Q13111|ensembl:ENSP00000301280|dip:DIP-31135N|uniprotkb:Q13111(identity)|entrezgene/locuslink:10036(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:VVbW9mpUGYMRPxvlEk9FERHIsJs9606 rogid:8ZlQPVvmtN638aK8ZblErN5Bhjo9606 intact-crc:026815AE27126A27|rigid:NgZwEzebNuoxrI25ak8BdL+tdCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13112 uniprotkb:P45973 intact:EBI-1052944|uniprotkb:Q99548|ensembl:ENSP00000315700 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 psi-mi:caf1b_human(display_long)|uniprotkb:Chromatin assembly factor I p60 subunit(gene name synonym)|uniprotkb:M-phase phosphoprotein 7(gene name synonym)|uniprotkb:CHAF1B(gene name)|psi-mi:CHAF1B(display_short)|uniprotkb:CAF1A(gene name synonym)|uniprotkb:CAF1P60(gene name synonym)|uniprotkb:MPHOSPH7(gene name synonym)|uniprotkb:MPP7(gene name synonym) psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831214|imex:IM-21659-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005432.1|dip:DIP-29243N|ensembl:ENSG00000159259(gene)|ensembl:ENST00000314103(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR029129|interpro:IPR036322|mint:Q13112|refseq:XP_016883966.1|refseq:XP_016883967.1|uniprotkb:Q13112(identity)|ddbj/embl/genbank:BC021218(identity)|entrezgene/locuslink:8208(identity) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|entrezgene/locuslink:23468(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:VVbW9mpUGYMRPxvlEk9FERHIsJs9606 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 intact-crc:026815AE27126A27|rigid:NgZwEzebNuoxrI25ak8BdL+tdCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13112 uniprotkb:Q04637 intact:EBI-1052944|uniprotkb:Q99548|ensembl:ENSP00000315700 intact:EBI-73711|uniprotkb:O43177|uniprotkb:O95066|uniprotkb:Q5HYG0|uniprotkb:Q6ZN21|uniprotkb:Q8N102|intact:EBI-11020102|uniprotkb:D3DNT4|uniprotkb:D3DNT5|uniprotkb:D3DNT2|uniprotkb:E9PFM1|uniprotkb:G5E9S1|intact:EBI-28974642|ensembl:ENSP00000316879 psi-mi:caf1b_human(display_long)|uniprotkb:Chromatin assembly factor I p60 subunit(gene name synonym)|uniprotkb:M-phase phosphoprotein 7(gene name synonym)|uniprotkb:CHAF1B(gene name)|psi-mi:CHAF1B(display_short)|uniprotkb:CAF1A(gene name synonym)|uniprotkb:CAF1P60(gene name synonym)|uniprotkb:MPHOSPH7(gene name synonym)|uniprotkb:MPP7(gene name synonym) psi-mi:if4g1_human(display_long)|uniprotkb:p220(gene name synonym)|uniprotkb:EIF4G1(gene name)|psi-mi:EIF4G1(display_short)|uniprotkb:EIF4G(gene name synonym)|uniprotkb:EIF4GI(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831214|imex:IM-21659-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005432.1|dip:DIP-29243N|ensembl:ENSG00000159259(gene)|ensembl:ENST00000314103(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR029129|interpro:IPR036322|mint:Q13112|refseq:XP_016883966.1|refseq:XP_016883967.1|uniprotkb:Q13112(identity)|ddbj/embl/genbank:BC021218(identity)|entrezgene/locuslink:8208(identity) ensembl:ENST00000342981|ensembl:ENSP00000343450|ensembl:ENSP00000316879|ensembl:ENST00000350481|ensembl:ENSP00000317600|ensembl:ENST00000352767|ensembl:ENSP00000338020|ensembl:ENST00000382330|ensembl:ENSP00000371767|ensembl:ENST00000392537|ensembl:ENSP00000376320|ensembl:ENST00000414031|ensembl:ENSP00000391935|ensembl:ENST00000424196|ensembl:ENSP00000416255|ensembl:ENST00000434061|ensembl:ENSP00000411826|refseq:NP_886553.3|refseq:NP_937884.1|refseq:NP_937885.1|refseq:NP_004944.3|dip:DIP-1161N|ensembl:ENSG00000114867(gene)|ensembl:ENST00000346169(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016020"(membrane)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032502"(developmental process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034645"(cellular macromolecule biosynthetic process)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0080135"(regulation of cellular response to stress)|go:"GO:0097009"(energy homeostasis)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1905537"(positive regulation of eukaryotic translation initiation factor 4F complex assembly)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1905612"(positive regulation of mRNA cap binding)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1905696"(regulation of polysome binding)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR037584|mint:Q04637|rcsb pdb:1LJ2|rcsb pdb:1UG3|rcsb pdb:2W97|rcsb pdb:4AZA|rcsb pdb:4F02|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5T46|rcsb pdb:6ZMW|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|uniprotkb:Q04637(identity)|entrezgene/locuslink:1981(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:VVbW9mpUGYMRPxvlEk9FERHIsJs9606 rogid:0UfVxxWOLUvrvFfcteeTc2RrbhA9606 intact-crc:026815AE27126A27|rigid:NgZwEzebNuoxrI25ak8BdL+tdCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13112 uniprotkb:Q9NVP2 intact:EBI-1052944|uniprotkb:Q99548|ensembl:ENSP00000315700 intact:EBI-1055650|uniprotkb:Q53G51|uniprotkb:Q9NVZ0|ensembl:ENSP00000263382|ensembl:ENSP00000499863 psi-mi:caf1b_human(display_long)|uniprotkb:Chromatin assembly factor I p60 subunit(gene name synonym)|uniprotkb:M-phase phosphoprotein 7(gene name synonym)|uniprotkb:CHAF1B(gene name)|psi-mi:CHAF1B(display_short)|uniprotkb:CAF1A(gene name synonym)|uniprotkb:CAF1P60(gene name synonym)|uniprotkb:MPHOSPH7(gene name synonym)|uniprotkb:MPP7(gene name synonym) psi-mi:asf1b_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog B(gene name synonym)|uniprotkb:CCG1-interacting factor A-II(gene name synonym)|uniprotkb:ASF1B(gene name)|psi-mi:ASF1B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831214|imex:IM-21659-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005432.1|dip:DIP-29243N|ensembl:ENSG00000159259(gene)|ensembl:ENST00000314103(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR029129|interpro:IPR036322|mint:Q13112|refseq:XP_016883966.1|refseq:XP_016883967.1|uniprotkb:Q13112(identity)|ddbj/embl/genbank:BC021218(identity)|entrezgene/locuslink:8208(identity) refseq:NP_060624.1|ensembl:ENSG00000105011(gene)|ensembl:ENSG00000288210(gene)|ensembl:ENST00000263382(transcript)|ensembl:ENST00000672225(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9NVP2|rcsb pdb:5BNX|rcsb pdb:5BO0|dip:DIP-29242N|uniprotkb:Q9NVP2(identity)|entrezgene/locuslink:55723(identity) psi-mi:"MI:0469"(intact) - caution:This sequence has been withdrawn from Uniprot. figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:VVbW9mpUGYMRPxvlEk9FERHIsJs9606 rogid:gG2Px6QOw95EohRaaWivH7GrSr09606 intact-crc:026815AE27126A27|rigid:NgZwEzebNuoxrI25ak8BdL+tdCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13112 uniprotkb:Q9UHV9 intact:EBI-1052944|uniprotkb:Q99548|ensembl:ENSP00000315700 intact:EBI-359873|uniprotkb:Q9P0P7|uniprotkb:Q9UN05|ensembl:ENSP00000356989 psi-mi:caf1b_human(display_long)|uniprotkb:Chromatin assembly factor I p60 subunit(gene name synonym)|uniprotkb:M-phase phosphoprotein 7(gene name synonym)|uniprotkb:CHAF1B(gene name)|psi-mi:CHAF1B(display_short)|uniprotkb:CAF1A(gene name synonym)|uniprotkb:CAF1P60(gene name synonym)|uniprotkb:MPHOSPH7(gene name synonym)|uniprotkb:MPP7(gene name synonym) psi-mi:pfd2_human(display_long)|uniprotkb:HSPC231(orf name)|uniprotkb:PFDN2(gene name)|psi-mi:PFDN2(display_short)|uniprotkb:PFD2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831214|imex:IM-21659-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005432.1|dip:DIP-29243N|ensembl:ENSG00000159259(gene)|ensembl:ENST00000314103(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR029129|interpro:IPR036322|mint:Q13112|refseq:XP_016883966.1|refseq:XP_016883967.1|uniprotkb:Q13112(identity)|ddbj/embl/genbank:BC021218(identity)|entrezgene/locuslink:8208(identity) refseq:NP_036526.2|refseq:XP_011507926.1|ensembl:ENSG00000143256(gene)|ensembl:ENST00000368010(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|interpro:IPR027235|mint:Q9UHV9|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957|dip:DIP-27557N|uniprotkb:Q9UHV9(identity)|entrezgene/locuslink:5202(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:VVbW9mpUGYMRPxvlEk9FERHIsJs9606 rogid:rgr14h3vGyzHxHoNJtlHBQkvhUE9606 intact-crc:026815AE27126A27|rigid:NgZwEzebNuoxrI25ak8BdL+tdCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13112 uniprotkb:Q13185 intact:EBI-1052944|uniprotkb:Q99548|ensembl:ENSP00000315700 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:caf1b_human(display_long)|uniprotkb:Chromatin assembly factor I p60 subunit(gene name synonym)|uniprotkb:M-phase phosphoprotein 7(gene name synonym)|uniprotkb:CHAF1B(gene name)|psi-mi:CHAF1B(display_short)|uniprotkb:CAF1A(gene name synonym)|uniprotkb:CAF1P60(gene name synonym)|uniprotkb:MPHOSPH7(gene name synonym)|uniprotkb:MPP7(gene name synonym) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831214|imex:IM-21659-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005432.1|dip:DIP-29243N|ensembl:ENSG00000159259(gene)|ensembl:ENST00000314103(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR029129|interpro:IPR036322|mint:Q13112|refseq:XP_016883966.1|refseq:XP_016883967.1|uniprotkb:Q13112(identity)|ddbj/embl/genbank:BC021218(identity)|entrezgene/locuslink:8208(identity) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:VVbW9mpUGYMRPxvlEk9FERHIsJs9606 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 intact-crc:026815AE27126A27|rigid:NgZwEzebNuoxrI25ak8BdL+tdCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13112 uniprotkb:Q13263 intact:EBI-1052944|uniprotkb:Q99548|ensembl:ENSP00000315700 intact:EBI-78139|uniprotkb:O00677|ensembl:ENSP00000253024|uniprotkb:Q7Z632|uniprotkb:Q93040|uniprotkb:Q96IM1 psi-mi:caf1b_human(display_long)|uniprotkb:Chromatin assembly factor I p60 subunit(gene name synonym)|uniprotkb:M-phase phosphoprotein 7(gene name synonym)|uniprotkb:CHAF1B(gene name)|psi-mi:CHAF1B(display_short)|uniprotkb:CAF1A(gene name synonym)|uniprotkb:CAF1P60(gene name synonym)|uniprotkb:MPHOSPH7(gene name synonym)|uniprotkb:MPP7(gene name synonym) psi-mi:tif1b_human(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831214|imex:IM-21659-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005432.1|dip:DIP-29243N|ensembl:ENSG00000159259(gene)|ensembl:ENST00000314103(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR029129|interpro:IPR036322|mint:Q13112|refseq:XP_016883966.1|refseq:XP_016883967.1|uniprotkb:Q13112(identity)|ddbj/embl/genbank:BC021218(identity)|entrezgene/locuslink:8208(identity) ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6QAJ|rcsb pdb:6QU1|reactome:R-HSA-212436|reactome:R-HSA-3899300|reactome:R-HSA-9609690|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q13263|rcsb pdb:1FP0|rcsb pdb:2RO1|rcsb pdb:2YVR|rcsb pdb:6H3A|rcsb pdb:6I9H|refseq:NP_005753.1|dip:DIP-30891N|uniprotkb:Q13263(identity)|entrezgene/locuslink:10155(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:VVbW9mpUGYMRPxvlEk9FERHIsJs9606 rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606 intact-crc:026815AE27126A27|rigid:NgZwEzebNuoxrI25ak8BdL+tdCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13112 uniprotkb:Q09028 intact:EBI-1052944|uniprotkb:Q99548|ensembl:ENSP00000315700 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 psi-mi:caf1b_human(display_long)|uniprotkb:Chromatin assembly factor I p60 subunit(gene name synonym)|uniprotkb:M-phase phosphoprotein 7(gene name synonym)|uniprotkb:CHAF1B(gene name)|psi-mi:CHAF1B(display_short)|uniprotkb:CAF1A(gene name synonym)|uniprotkb:CAF1P60(gene name synonym)|uniprotkb:MPHOSPH7(gene name synonym)|uniprotkb:MPP7(gene name synonym) psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831214|imex:IM-21659-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005432.1|dip:DIP-29243N|ensembl:ENSG00000159259(gene)|ensembl:ENST00000314103(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR029129|interpro:IPR036322|mint:Q13112|refseq:XP_016883966.1|refseq:XP_016883967.1|uniprotkb:Q13112(identity)|ddbj/embl/genbank:BC021218(identity)|entrezgene/locuslink:8208(identity) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|entrezgene/locuslink:5928(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:VVbW9mpUGYMRPxvlEk9FERHIsJs9606 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 intact-crc:026815AE27126A27|rigid:NgZwEzebNuoxrI25ak8BdL+tdCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13112 uniprotkb:Q9NQP4 intact:EBI-1052944|uniprotkb:Q99548|ensembl:ENSP00000315700 intact:EBI-357021|uniprotkb:Q5TD11|uniprotkb:Q92779|ensembl:ENSP00000360473 psi-mi:caf1b_human(display_long)|uniprotkb:Chromatin assembly factor I p60 subunit(gene name synonym)|uniprotkb:M-phase phosphoprotein 7(gene name synonym)|uniprotkb:CHAF1B(gene name)|psi-mi:CHAF1B(display_short)|uniprotkb:CAF1A(gene name synonym)|uniprotkb:CAF1P60(gene name synonym)|uniprotkb:MPHOSPH7(gene name synonym)|uniprotkb:MPP7(gene name synonym) psi-mi:pfd4_human(display_long)|uniprotkb:PFDN4(gene name)|psi-mi:PFDN4(display_short)|uniprotkb:PFD4(gene name synonym)|uniprotkb:Protein C-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831214|imex:IM-21659-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005432.1|dip:DIP-29243N|ensembl:ENSG00000159259(gene)|ensembl:ENST00000314103(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR029129|interpro:IPR036322|mint:Q13112|refseq:XP_016883966.1|refseq:XP_016883967.1|uniprotkb:Q13112(identity)|ddbj/embl/genbank:BC021218(identity)|entrezgene/locuslink:8208(identity) refseq:NP_002614.2|ensembl:ENSG00000101132(gene)|ensembl:ENST00000371419(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|interpro:IPR016661(Prefoldin, subunit 4)|mint:Q9NQP4|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957|uniprotkb:Q9NQP4(identity)|entrezgene/locuslink:5203(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:VVbW9mpUGYMRPxvlEk9FERHIsJs9606 rogid:oXbJiHxqcYHrAWGGgzV81ocGt889606 intact-crc:026815AE27126A27|rigid:NgZwEzebNuoxrI25ak8BdL+tdCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13112 uniprotkb:P84243 intact:EBI-1052944|uniprotkb:Q99548|ensembl:ENSP00000315700 intact:EBI-120658|uniprotkb:P06351|uniprotkb:P33155|uniprotkb:Q5VV55|uniprotkb:Q5VV56|uniprotkb:Q66I33|uniprotkb:Q9V3W4|ensembl:ENSP00000254810|ensembl:ENSP00000355778|ensembl:ENSP00000355780|ensembl:ENSP00000355781|ensembl:ENSP00000465813|ensembl:ENSP00000466020|ensembl:ENSP00000468714|ensembl:ENSP00000499275|ensembl:ENSP00000499385|ensembl:ENSP00000499800 psi-mi:caf1b_human(display_long)|uniprotkb:Chromatin assembly factor I p60 subunit(gene name synonym)|uniprotkb:M-phase phosphoprotein 7(gene name synonym)|uniprotkb:CHAF1B(gene name)|psi-mi:CHAF1B(display_short)|uniprotkb:CAF1A(gene name synonym)|uniprotkb:CAF1P60(gene name synonym)|uniprotkb:MPHOSPH7(gene name synonym)|uniprotkb:MPP7(gene name synonym) psi-mi:h33_human(display_long)|uniprotkb:H3-3A(gene name)|psi-mi:H3-3A(display_short)|uniprotkb:H3-3B(gene name)|psi-mi:H3-3B(display_short)|uniprotkb:H3.3A(gene name synonym)|uniprotkb:H3.3B(gene name synonym)|uniprotkb:H3F3(gene name synonym)|uniprotkb:H3F3A(gene name synonym)|uniprotkb:H3F3B(gene name synonym)|uniprotkb:PP781(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831214|imex:IM-21659-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005432.1|dip:DIP-29243N|ensembl:ENSG00000159259(gene)|ensembl:ENST00000314103(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR029129|interpro:IPR036322|mint:Q13112|refseq:XP_016883966.1|refseq:XP_016883967.1|uniprotkb:Q13112(identity)|ddbj/embl/genbank:BC021218(identity)|entrezgene/locuslink:8208(identity) refseq:NP_002098.1|refseq:NP_005315.1|rcsb pdb:4H9N|rcsb pdb:3QL9|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:3QLA|rcsb pdb:3QLC|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4L58|rcsb pdb:4N4I|rcsb pdb:3WTP|rcsb pdb:4O62|rcsb pdb:4QQ4|rcsb pdb:4TMP|rcsb pdb:4GNE|rcsb pdb:4GNF|rcsb pdb:4U7T|rcsb pdb:4GNG|rcsb pdb:4W5A|rcsb pdb:4GU0|rcsb pdb:4GUR|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:4GUS|rcsb pdb:4GY5|rcsb pdb:5DWQ|rcsb pdb:5DX0|rcsb pdb:5JA4|rcsb pdb:5JJY|ensembl:ENSG00000132475(gene)|ensembl:ENSG00000163041(gene)|rcsb pdb:5JLB|rcsb pdb:5KDM|rcsb pdb:5X7X|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6HGT|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6J9J|rcsb pdb:6PZV|rcsb pdb:6QXZ|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6U04|rcsb pdb:7A08|reactome:R-HSA-427413|rcsb pdb:7CIZ|reactome:R-HSA-5250924|reactome:R-HSA-5334118|rcsb pdb:7CJ0|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-983231|rcsb pdb:7CWH|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-427359|reactome:R-HSA-427389|ensembl:ENST00000254810(transcript)|ensembl:ENST00000366813(transcript)|ensembl:ENST00000366815(transcript)|ensembl:ENST00000366816(transcript)|ensembl:ENST00000586607(transcript)|ensembl:ENST00000587560(transcript)|ensembl:ENST00000589599(transcript)|ensembl:ENST00000655399(transcript)|ensembl:ENST00000661429(transcript)|ensembl:ENST00000666609(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P84243|rcsb pdb:2L43|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3AV2|rcsb pdb:3JVK|rcsb pdb:3MUK|rcsb pdb:3MUL|dip:DIP-40046N|uniprotkb:P84243(identity)|entrezgene/locuslink:3021(identity)|entrezgene/locuslink:3020(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:VVbW9mpUGYMRPxvlEk9FERHIsJs9606 rogid:cRqA5/IBNfIbbxAnbwLqzXip20I9606 intact-crc:026815AE27126A27|rigid:NgZwEzebNuoxrI25ak8BdL+tdCw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q9H081 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-1001205|uniprotkb:Q96N24|ensembl:ENSP00000370557|ensembl:ENSP00000461252|ensembl:ENSP00000484532 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:mis12_human(display_long)|uniprotkb:MIS12(gene name)|psi-mi:MIS12(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) refseq:NP_001245146.1|refseq:NP_001245147.1|refseq:NP_001245148.1|refseq:NP_001245149.1|refseq:XP_016880522.1|refseq:XP_016880523.1|refseq:XP_016880524.1|refseq:NP_076944.1|ensembl:ENSG00000167842(gene)|ensembl:ENST00000381165(transcript)|ensembl:ENST00000573759(transcript)|ensembl:ENST00000611091(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR008685(Mis12)|mint:Q9H081|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_005256854.1|uniprotkb:Q9H081(identity)|entrezgene/locuslink:79003(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:1qNMwDq3AYOWnRnPa2u3yt7O4109606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q7Z3K3 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-1389308|uniprotkb:O75049|uniprotkb:Q5SZS2|uniprotkb:Q5SZS3|uniprotkb:Q5SZS4|uniprotkb:Q8TDZ7|uniprotkb:Q9Y4X7|uniprotkb:Q3LIC4|uniprotkb:Q5SZS1|intact:EBI-2560449|intact:EBI-11742841|uniprotkb:B4DTP8|uniprotkb:B4DYL9|uniprotkb:B7ZBY5|uniprotkb:E9PM80|intact:EBI-14072025|intact:EBI-17205119|intact:EBI-22321456|intact:EBI-12748249|intact:EBI-16429759|ensembl:ENSP00000271715 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:pogz_human(display_long)|uniprotkb:POGZ(gene name)|psi-mi:POGZ(display_short)|uniprotkb:KIAA0461(gene name synonym)|uniprotkb:Nbla00003(orf name)|uniprotkb:SUHW5(gene name synonym)|uniprotkb:ZNF280E(gene name synonym)|uniprotkb:ZNF635(gene name synonym)|uniprotkb:Suppressor of hairy wing homolog 5(gene name synonym)|uniprotkb:Zinc finger protein 280E(gene name synonym)|uniprotkb:Zinc finger protein 635(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) refseq:NP_001181866.1|refseq:NP_001181867.1|refseq:NP_055915.2|refseq:NP_665739.3|refseq:NP_997054.1|refseq:XP_016856234.1|refseq:XP_016856235.1|refseq:XP_016856237.1|refseq:XP_016856238.1|refseq:XP_005245056.1|refseq:XP_005245057.1|refseq:XP_005245058.1|refseq:XP_005245062.1|refseq:XP_005245063.1|dip:DIP-38044N|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSG00000143442(gene)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|ensembl:ENST00000271715(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR004875(CENP-B protein)|interpro:IPR006600(Centromere protein B, helix-turn-helix)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q7Z3K3|rcsb pdb:2E72|rcsb pdb:2N3A|rcsb pdb:6EMP|uniprotkb:Q7Z3K3(identity)|entrezgene/locuslink:23126(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:sCOIY8KsHRQtfcoSA9Tixl9yIsc9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q9H410 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-1001144|uniprotkb:E1P5U9|uniprotkb:Q5JW56|uniprotkb:Q9H8P4|ensembl:ENSP00000362855|ensembl:ENSP00000389810|uniprotkb:Q5JW55|uniprotkb:B4DWT2 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:dsn1_human(display_long)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)|uniprotkb:C20orf172(gene name synonym)|uniprotkb:MIS13(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) refseq:NP_001138789.1|refseq:NP_001138787.1|refseq:NP_001138788.1|refseq:NP_079194.3|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-68877|reactome:R-HSA-9648025|rcsb pdb:5LSK|ensembl:ENSG00000149636(gene)|ensembl:ENST00000373750(transcript)|ensembl:ENST00000426836(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000939"(inner kinetochore)|go:"GO:0001650"(fibrillar center)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0051301"(cell division)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|mint:Q9H410|rcsb pdb:5LSI|rcsb pdb:5LSJ|refseq:NP_001138790.1|refseq:XP_006723939.1|entrezgene/locuslink:79980(identity)|uniprotkb:Q9H410(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:cJ0wCtpLS+YkMj83k/SubkpHwuE9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q96IY1 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-2554690|uniprotkb:Q9H2M5|uniprotkb:Q5SY75|uniprotkb:Q9Y415|uniprotkb:Q9NRN8|ensembl:ENSP00000355944|uniprotkb:E7ETD5 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:nsl1_human(display_long)|uniprotkb:C1orf48(gene name synonym)|uniprotkb:DC8(orf name)|uniprotkb:DC31(orf name)|uniprotkb:MIS14(orf name)|uniprotkb:NSL1(gene name)|psi-mi:NSL1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) refseq:NP_056286.3|ensembl:ENSG00000117697(gene)|ensembl:ENST00000366977(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|go:"GO:0051301"(cell division)|interpro:IPR013950(Kinetochore Mis14)|mint:Q96IY1|rcsb pdb:4NF9|rcsb pdb:5LSI|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-2500257|reactome:R-HSA-9648025|refseq:NP_001036014.1|uniprotkb:Q96IY1(identity)|entrezgene/locuslink:25936(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:w4K2MEHLfZvFECNhtDanXWF0LQk9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q8IY57 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|entrezgene/locuslink:10138(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:P61964 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|entrezgene/locuslink:11091(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q969R5 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750|uniprotkb:Q969R5(identity)|entrezgene/locuslink:83746(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q5VZL5 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-2514659|intact:EBI-28984130|ensembl:ENSP00000322915|uniprotkb:A0JP19|uniprotkb:O43308|uniprotkb:A0JP20|uniprotkb:Q5T5E2|uniprotkb:Q7L3Q4|uniprotkb:Q5T5E1|intact:EBI-2556245 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:zmym4_human(display_long)|uniprotkb:ZMYM4(gene name)|psi-mi:ZMYM4(display_short)|uniprotkb:KIAA0425(gene name synonym)|uniprotkb:ZNF262(gene name synonym)|uniprotkb:Zinc finger protein 262(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) ensembl:ENSG00000146463(gene)|ensembl:ENST00000314607(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022604"(regulation of cell morphogenesis)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR021893|refseq:XP_016858292.1|refseq:XP_016858293.1|refseq:XP_011540725.1|refseq:XP_011540727.1|refseq:NP_005086.2|ensembl:ENSP00000322915|refseq:XP_005271388.1|uniprotkb:Q5VZL5(identity)|entrezgene/locuslink:9202(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:jc8YwR+37J3uD08cXiUnOA2hHEI9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:P84243 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-120658|uniprotkb:P06351|uniprotkb:P33155|uniprotkb:Q5VV55|uniprotkb:Q5VV56|uniprotkb:Q66I33|uniprotkb:Q9V3W4|ensembl:ENSP00000254810|ensembl:ENSP00000355778|ensembl:ENSP00000355780|ensembl:ENSP00000355781|ensembl:ENSP00000465813|ensembl:ENSP00000466020|ensembl:ENSP00000468714|ensembl:ENSP00000499275|ensembl:ENSP00000499385|ensembl:ENSP00000499800 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:h33_human(display_long)|uniprotkb:H3-3A(gene name)|psi-mi:H3-3A(display_short)|uniprotkb:H3-3B(gene name)|psi-mi:H3-3B(display_short)|uniprotkb:H3.3A(gene name synonym)|uniprotkb:H3.3B(gene name synonym)|uniprotkb:H3F3(gene name synonym)|uniprotkb:H3F3A(gene name synonym)|uniprotkb:H3F3B(gene name synonym)|uniprotkb:PP781(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) refseq:NP_002098.1|refseq:NP_005315.1|rcsb pdb:4H9N|rcsb pdb:3QL9|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:3QLA|rcsb pdb:3QLC|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4L58|rcsb pdb:4N4I|rcsb pdb:3WTP|rcsb pdb:4O62|rcsb pdb:4QQ4|rcsb pdb:4TMP|rcsb pdb:4GNE|rcsb pdb:4GNF|rcsb pdb:4U7T|rcsb pdb:4GNG|rcsb pdb:4W5A|rcsb pdb:4GU0|rcsb pdb:4GUR|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:4GUS|rcsb pdb:4GY5|rcsb pdb:5DWQ|rcsb pdb:5DX0|rcsb pdb:5JA4|rcsb pdb:5JJY|ensembl:ENSG00000132475(gene)|ensembl:ENSG00000163041(gene)|rcsb pdb:5JLB|rcsb pdb:5KDM|rcsb pdb:5X7X|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6HGT|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6J9J|rcsb pdb:6PZV|rcsb pdb:6QXZ|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6U04|rcsb pdb:7A08|reactome:R-HSA-427413|rcsb pdb:7CIZ|reactome:R-HSA-5250924|reactome:R-HSA-5334118|rcsb pdb:7CJ0|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-983231|rcsb pdb:7CWH|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-427359|reactome:R-HSA-427389|ensembl:ENST00000254810(transcript)|ensembl:ENST00000366813(transcript)|ensembl:ENST00000366815(transcript)|ensembl:ENST00000366816(transcript)|ensembl:ENST00000586607(transcript)|ensembl:ENST00000587560(transcript)|ensembl:ENST00000589599(transcript)|ensembl:ENST00000655399(transcript)|ensembl:ENST00000661429(transcript)|ensembl:ENST00000666609(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P84243|rcsb pdb:2L43|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3AV2|rcsb pdb:3JVK|rcsb pdb:3MUK|rcsb pdb:3MUL|dip:DIP-40046N|uniprotkb:P84243(identity)|entrezgene/locuslink:3021(identity)|entrezgene/locuslink:3020(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:cRqA5/IBNfIbbxAnbwLqzXip20I9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q6P1K2 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-713832|uniprotkb:Q5TCJ8|uniprotkb:Q5TCJ9|uniprotkb:Q5TCK3|uniprotkb:Q69YZ9|uniprotkb:Q6PHR4|uniprotkb:Q86VJ6|uniprotkb:Q8N4T6|uniprotkb:Q9UBQ3|uniprotkb:A8K0C5|intact:EBI-2554676|uniprotkb:Q5TCK0|ensembl:ENSP00000357260|uniprotkb:Q5TCK1|uniprotkb:Q6ZVE6 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:pmf1_human(display_long)|uniprotkb:PMF1(gene name)|psi-mi:PMF1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) ensembl:ENSG00000160783(gene)|ensembl:ENST00000368277(transcript)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0051301"(cell division)|interpro:IPR007128(Nnf1)|mint:Q6P1K2|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001186582.1|refseq:NP_001186583.1|refseq:NP_001186590.1|refseq:NP_001186592.1|refseq:NP_009152.2|uniprotkb:Q6P1K2(identity)|entrezgene/locuslink:11243(identity)|entrezgene/locuslink:100527963(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:76xPGmFgI3Pt1gsZMb3aD4hpPWM9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q6AHZ1 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-2813764|uniprotkb:O15044|uniprotkb:A0PJI5|uniprotkb:Q32MP4|ensembl:ENSP00000479684|ensembl:ENSP00000481657|ensembl:ENSP00000485614 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:z518a_human(display_long)|uniprotkb:ZNF518A(gene name)|psi-mi:ZNF518A(display_short)|uniprotkb:KIAA0335(gene name synonym)|uniprotkb:ZNF518(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) refseq:XP_011538715.1|refseq:XP_011538717.1|refseq:XP_011538720.1|refseq:XP_011538721.1|refseq:XP_011538708.1|refseq:XP_011538722.1|refseq:XP_011538710.1|refseq:XP_011538712.1|refseq:XP_011538714.1|refseq:NP_055618.2|refseq:NP_001317661.1|refseq:NP_001317662.1|refseq:NP_001317663.1|refseq:NP_001317664.1|refseq:NP_001317665.1|refseq:NP_001317666.1|refseq:NP_001317667.1|refseq:XP_016872475.1|refseq:XP_016872478.1|refseq:XP_016872481.1|refseq:XP_016872483.1|refseq:XP_016872486.1|refseq:XP_016872487.1|refseq:XP_016872488.1|ensembl:ENSG00000177853(gene)|ensembl:ENST00000316045(transcript)|ensembl:ENST00000614149(transcript)|ensembl:ENST00000624776(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027760|interpro:IPR036236|refseq:NP_001265453.1|refseq:NP_001265454.1|refseq:NP_001265455.1|uniprotkb:Q6AHZ1(identity)|entrezgene/locuslink:9849(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:UjGW18sLz9JzoM8943TK/3P5VpY9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q13263 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-78139|uniprotkb:O00677|ensembl:ENSP00000253024|uniprotkb:Q7Z632|uniprotkb:Q93040|uniprotkb:Q96IM1 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:tif1b_human(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6QAJ|rcsb pdb:6QU1|reactome:R-HSA-212436|reactome:R-HSA-3899300|reactome:R-HSA-9609690|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q13263|rcsb pdb:1FP0|rcsb pdb:2RO1|rcsb pdb:2YVR|rcsb pdb:6H3A|rcsb pdb:6I9H|refseq:NP_005753.1|dip:DIP-30891N|uniprotkb:Q13263(identity)|entrezgene/locuslink:10155(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:O60684 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-359923|uniprotkb:Q5VVU3|uniprotkb:B2RDC7|ensembl:ENSP00000362728|uniprotkb:D3DPP5 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:ima7_human(display_long)|uniprotkb:KPNA6(gene name)|psi-mi:KPNA6(display_short)|uniprotkb:IPOA7(gene name synonym)|uniprotkb:Karyopherin subunit alpha-6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) refseq:NP_036448.1|ensembl:ENSG00000025800(gene)|ensembl:ENST00000373625(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0019079"(viral genome replication)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0043657"(host cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O60684|rcsb pdb:4UAD|dip:DIP-27609N|uniprotkb:O60684(identity)|entrezgene/locuslink:23633(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:3NsSIcE6BHIqYlvfGRolUKD/5uc9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q8N488 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|uniprotkb:Q8N488(identity)|entrezgene/locuslink:23429(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:O95785 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-1387294|uniprotkb:B7ZM82|uniprotkb:Q4G0E0|uniprotkb:Q6P6B0|uniprotkb:Q6ZN24|uniprotkb:Q7LDY6|uniprotkb:Q7LDZ1|uniprotkb:Q96IG5|uniprotkb:Q96SQ6|uniprotkb:Q9BUR8|uniprotkb:Q9NPT1|intact:EBI-10967552|uniprotkb:B3KVH1|uniprotkb:M0QY21 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:wiz_human(display_long)|uniprotkb:WIZ(gene name)|psi-mi:WIZ(display_short)|uniprotkb:ZNF803(gene name synonym)|uniprotkb:Widely-interspaced zinc finger-containing protein(gene name synonym)|uniprotkb:Zinc finger protein 803(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) refseq:NP_067064.2|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001317324.1|interpro:IPR036236|mint:O95785|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|go:"GO:0030496"(midbody)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990226"(histone methyltransferase binding)|uniprotkb:O95785(identity)|entrezgene/locuslink:58525(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:FMQwuMDlEC/Zdsnayyl7kpQSmyg9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q13112 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-1052944|uniprotkb:Q99548|ensembl:ENSP00000315700 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:caf1b_human(display_long)|uniprotkb:Chromatin assembly factor I p60 subunit(gene name synonym)|uniprotkb:M-phase phosphoprotein 7(gene name synonym)|uniprotkb:CHAF1B(gene name)|psi-mi:CHAF1B(display_short)|uniprotkb:CAF1A(gene name synonym)|uniprotkb:CAF1P60(gene name synonym)|uniprotkb:MPHOSPH7(gene name synonym)|uniprotkb:MPP7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) refseq:NP_005432.1|dip:DIP-29243N|ensembl:ENSG00000159259(gene)|ensembl:ENST00000314103(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR029129|interpro:IPR036322|mint:Q13112|refseq:XP_016883966.1|refseq:XP_016883967.1|uniprotkb:Q13112(identity)|entrezgene/locuslink:8208(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:VVbW9mpUGYMRPxvlEk9FERHIsJs9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q6IQ32 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-2838654|uniprotkb:A8K951|uniprotkb:Q9H9P3|uniprotkb:O94943|ensembl:ENSP00000262198 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:adnp2_human(display_long)|uniprotkb:ADNP2(gene name)|psi-mi:ADNP2(display_short)|uniprotkb:KIAA0863(gene name synonym)|uniprotkb:ZNF508(gene name synonym)|uniprotkb:Zinc finger protein 508(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) refseq:NP_055728.1|refseq:XP_005266713.1|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0046872"(metal ion binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071300"(cellular response to retinoic acid)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR038861|mint:Q6IQ32|ensembl:ENSG00000101544(gene)|ensembl:ENST00000262198(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|uniprotkb:Q6IQ32(identity)|entrezgene/locuslink:22850(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:yzYCNBnFFszXO4X7vp01+DcaGvs9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:P49368 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N|uniprotkb:P49368(identity)|entrezgene/locuslink:7203(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:O75556 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-8830751|ensembl:ENSP00000244930 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:sg2a1_human(display_long)|uniprotkb:LIPHC(gene name synonym)|uniprotkb:Lacryglobin(gene name synonym)|uniprotkb:Lipophilin-C(gene name synonym)|uniprotkb:MGB2(gene name synonym)|uniprotkb:Mammaglobin-2(gene name synonym)|uniprotkb:Secretoglobin family 2A member 1(gene name synonym)|uniprotkb:UGB3(gene name synonym)|uniprotkb:SCGB2A1(gene name)|psi-mi:SCGB2A1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) refseq:NP_002398.1|ensembl:ENSG00000124939(gene)|ensembl:ENST00000244930(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0030521"(androgen receptor signaling pathway)|interpro:IPR016126(Secretoglobin)|interpro:IPR035960|uniprotkb:O75556(identity)|entrezgene/locuslink:4246(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:w+3NKAb7Len68q3aS4Re1qKbOac9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:P63167 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-349105|uniprotkb:Q15701|ensembl:ENSP00000242577|ensembl:ENSP00000376296|ensembl:ENSP00000376297|ensembl:ENSP00000446614|ensembl:ENSP00000447907 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:dyl1_human(display_long)|uniprotkb:DYNLL1(gene name)|psi-mi:DYNLL1(display_short)|uniprotkb:DLC1(gene name synonym)|uniprotkb:DNCLC1(gene name synonym)|uniprotkb:HDLC1(gene name synonym)|uniprotkb:Dynein light chain LC8-type 1(gene name synonym)|uniprotkb:8 kDa dynein light chain(gene name synonym)|uniprotkb:Protein inhibitor of neuronal nitric oxide synthase(gene name synonym)|uniprotkb:DNCL1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) refseq:NP_001032583.1|refseq:NP_001032584.1|refseq:NP_003737.1|go:"GO:0072686"(mitotic spindle)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:P63167|rcsb pdb:1CMI|rcsb pdb:3ZKE|rcsb pdb:3ZKF|rcsb pdb:6GZJ|rcsb pdb:6GZL|rcsb pdb:6RLB|rcsb pdb:6SC2|rcsb pdb:7D35|reactome:R-HSA-111446|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|go:"GO:0000776"(kinetochore)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0005829"(cytosol)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007286"(spermatid development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030286"(dynein complex)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|ensembl:ENSG00000088986(gene)|ensembl:ENST00000242577(transcript)|ensembl:ENST00000392508(transcript)|ensembl:ENST00000392509(transcript)|ensembl:ENST00000548342(transcript)|ensembl:ENST00000549989(transcript)|dip:DIP-33150N|uniprotkb:P63167(identity)|entrezgene/locuslink:8655(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:Bra4LfaqYPMyo6xX9RD6G7Rdv809606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q96JM3 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-2560420|uniprotkb:Q8NC88|uniprotkb:B3KU06|uniprotkb:Q6P181|uniprotkb:Q9BST0|ensembl:ENSP00000354730|ensembl:ENSP00000496699 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:chap1_human(display_long)|uniprotkb:CHAMP(gene name synonym)|uniprotkb:CHAMP1(gene name)|psi-mi:CHAMP1(display_short)|uniprotkb:C13orf8(gene name synonym)|uniprotkb:CAMP(gene name synonym)|uniprotkb:KIAA1802(gene name synonym)|uniprotkb:ZNF828(gene name synonym)|uniprotkb:Zinc finger protein 828(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) refseq:NP_001157616.1|refseq:NP_001157617.1|refseq:NP_115812.1|ensembl:ENSG00000198824(gene)|ensembl:ENST00000361283(transcript)|ensembl:ENST00000643483(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0016604"(nuclear body)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0046872"(metal ion binding)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0090543"(Flemming body)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR039330|mint:Q96JM3|rcsb pdb:6EKJ|rcsb pdb:6EKL|rcsb pdb:5XPT|rcsb pdb:5XPU|uniprotkb:Q96JM3(identity)|entrezgene/locuslink:283489(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:Di1yMiufHKsy384vPjOgdncmQXw9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:O60281 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-1224010|uniprotkb:Q9H8G3|uniprotkb:Q9H8J4|uniprotkb:Q5W0B2|uniprotkb:Q7Z3L7|intact:EBI-28971048|ensembl:ENSP00000358590 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:zn292_human(display_long)|uniprotkb:ZNF292(gene name)|psi-mi:ZNF292(display_short)|uniprotkb:KIAA0530(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) ensembl:ENSP00000358590|refseq:NP_055836.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|ensembl:ENSG00000188994(gene)|interpro:IPR036236|mint:O60281|rcsb pdb:1X3C|ensembl:ENST00000369577(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|uniprotkb:O60281(identity)|entrezgene/locuslink:23036(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:4Ss6SyxGv1bSjSBhSjquUKutB349606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q14839 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-372916|uniprotkb:Q8IXZ5|intact:EBI-28978241|ensembl:ENSP00000440542 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:chd4_human(display_long)|uniprotkb:CHD4(gene name)|psi-mi:CHD4(display_short)|uniprotkb:ATP-dependent helicase CHD4(gene name synonym)|uniprotkb:Mi-2 autoantigen 218 kDa protein(gene name synonym)|uniprotkb:Mi2-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) ensembl:ENSP00000440542|ensembl:ENST00000645095|ensembl:ENSP00000496634|refseq:NP_001264.2|refseq:XP_006719021.1|refseq:NP_001284482.1|ensembl:ENSG00000111642(gene)|ensembl:ENST00000544040(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070615"|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q14839|rcsb pdb:1MM2|rcsb pdb:1MM3|rcsb pdb:2EE1|rcsb pdb:2L5U|rcsb pdb:2L75|rcsb pdb:2N5N|rcsb pdb:4O9I|rcsb pdb:6BGG|rcsb pdb:6Q3M|rcsb pdb:6RYR|rcsb pdb:6RYU|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9031628|reactome:R-HSA-9679191|dip:DIP-31183N|uniprotkb:Q14839(identity)|entrezgene/locuslink:1108(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:E9eHT/41SIFRiz54J81hvPQeHIE9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q6N043 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-4395404|uniprotkb:A1L495|uniprotkb:B2RMT6|uniprotkb:Q6MZM6|uniprotkb:Q6N085|uniprotkb:Q9H0U5|uniprotkb:Q9HCI8|uniprotkb:Q9NXS0|uniprotkb:Q6P2R6|uniprotkb:Q7Z6J5|intact:EBI-28970145|ensembl:ENSP00000267807 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:z280d_human(display_long)|uniprotkb:ZNF280D(gene name)|psi-mi:ZNF280D(display_short)|uniprotkb:KIAA1584(gene name synonym)|uniprotkb:SUHW4(gene name synonym)|uniprotkb:ZNF634(gene name synonym)|uniprotkb:Suppressor of hairy wing homolog 4(gene name synonym)|uniprotkb:Zinc finger protein 634(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) ensembl:ENSP00000267807|ensembl:ENST00000558067|ensembl:ENSP00000454173|ensembl:ENST00000558320|ensembl:ENSP00000453706|ensembl:ENST00000559237|ensembl:ENSP00000454111|ensembl:ENST00000560002|ensembl:ENSP00000453636|refseq:XP_011520004.1|refseq:NP_001002843.1|refseq:NP_060131.2|refseq:NP_001275517.1|refseq:NP_001002844.1|refseq:NP_001275518.1|refseq:XP_016877833.1|refseq:XP_016877834.1|ensembl:ENSG00000137871(gene)|ensembl:ENST00000267807(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR025243|interpro:IPR036236|mint:Q6N043|uniprotkb:Q6N043(identity)|entrezgene/locuslink:54816(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:BYkVW7yPK+LxorbA2quTgne0Txs9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q9P0T4 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-745520|uniprotkb:B2RDM6|ensembl:ENSP00000270451|ensembl:ENSP00000466047|ensembl:ENSP00000466564 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:zn581_human(display_long)|uniprotkb:ZNF581(gene name)|psi-mi:ZNF581(display_short)|uniprotkb:HSPC189(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) refseq:NP_057619.1|ensembl:ENSG00000171425(gene)|ensembl:ENST00000270451(transcript)|ensembl:ENST00000587252(transcript)|ensembl:ENST00000588537(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9P0T4|go:"GO:0005634"(nucleus)|refseq:XP_006723303.1|refseq:XP_016882356.1|uniprotkb:Q9P0T4(identity)|entrezgene/locuslink:51545(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:SpE0ZPhcfXB4PnyufoyWq4iNAs89606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q99496 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|entrezgene/locuslink:6045(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q9H582 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-2560435|uniprotkb:Q7LG67|uniprotkb:Q5TCC0|uniprotkb:Q6PI06|uniprotkb:Q9ULJ9|uniprotkb:A2RU71|uniprotkb:Q2TAM0|uniprotkb:Q6P446|uniprotkb:Q6BEP7|ensembl:ENSP00000337008|ensembl:ENSP00000359469 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:zn644_human(display_long)|uniprotkb:ZNF644(gene name)|psi-mi:ZNF644(display_short)|uniprotkb:KIAA1221(gene name synonym)|uniprotkb:ZEP2(gene name synonym)|uniprotkb:Zinc finger motif enhancer-binding protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) refseq:NP_057704.2|refseq:NP_115562.3|refseq:NP_958357.1|refseq:XP_016857977.1|refseq:XP_016857978.1|refseq:XP_016857979.1|refseq:XP_016857980.1|refseq:XP_016857981.1|refseq:XP_016857982.1|refseq:XP_016857983.1|ensembl:ENSG00000122482(gene)|ensembl:ENST00000337393(transcript)|ensembl:ENST00000370440(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9H582|uniprotkb:Q9H582(identity)|entrezgene/locuslink:84146(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:16MjfkV6aoDArzVV5Qi0K2HI2lg9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q9H9B1 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-766087|uniprotkb:Q8TCN7|uniprotkb:Q96F53|uniprotkb:Q96JF1|uniprotkb:Q96KH4|uniprotkb:B1AQ58|uniprotkb:B1AQ59|uniprotkb:Q86X08|ensembl:ENSP00000417980 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:ehmt1_human(display_long)|uniprotkb:KMT1D(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 5(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 1(gene name synonym)|uniprotkb:G9a-like protein 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1D(gene name synonym)|uniprotkb:EHMT1(gene name)|psi-mi:EHMT1(display_short)|uniprotkb:EUHMTASE1(gene name synonym)|uniprotkb:KIAA1876(gene name synonym)|uniprotkb:GLP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) refseq:NP_001138999.1|refseq:NP_079033.4|ensembl:ENST00000371394|ensembl:ENSP00000485945|ensembl:ENSP00000417980|ensembl:ENST00000462484|ensembl:ENSP00000417328|dip:DIP-34585N|ensembl:ENSG00000181090(gene)|ensembl:ENST00000460843(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016604"(nuclear body)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038035|interpro:IPR043550|mint:Q9H9B1|rcsb pdb:2IGQ|rcsb pdb:2RFI|rcsb pdb:3B7B|rcsb pdb:3B95|rcsb pdb:3FPD|rcsb pdb:3HNA|rcsb pdb:3MO0|rcsb pdb:3MO2|rcsb pdb:3MO5|rcsb pdb:3SW9|rcsb pdb:3SWC|rcsb pdb:4I51|rcsb pdb:5TTG|rcsb pdb:5TUZ|rcsb pdb:5V9J|rcsb pdb:5VSD|rcsb pdb:5VSF|rcsb pdb:6BY9|rcsb pdb:6MBO|rcsb pdb:6MBP|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-6804760|reactome:R-HSA-8853884|reactome:R-HSA-8953750|uniprotkb:Q9H9B1(identity)|entrezgene/locuslink:79813(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:4L6QOGSsRPi8hDjS2/BYShjpnf89606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:P05089 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-2513844|uniprotkb:Q5JWT6|uniprotkb:Q5JWT5|uniprotkb:Q9BS50|uniprotkb:Q8TE72|uniprotkb:A6NEA0|ensembl:ENSP00000357066 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:argi1_human(display_long)|uniprotkb:ARG1(gene name)|psi-mi:ARG1(display_short)|uniprotkb:Type I arginase(gene name synonym)|uniprotkb:Liver-type arginase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) refseq:NP_000036.2|refseq:NP_001231367.1|ensembl:ENSG00000118520(gene)|ensembl:ENST00000368087(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0001889"(liver development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004053"(arginase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006527"(arginine catabolic process)|go:"GO:0007568"(aging)|go:"GO:0009635"(response to herbicide)|go:"GO:0010042"(response to manganese ion)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010963"|go:"GO:0014075"(response to amine)|go:"GO:0019547"(arginine catabolic process to ornithine)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030324"(lung development)|go:"GO:0032964"(collagen biosynthetic process)|go:"GO:0033189"(response to vitamin A)|go:"GO:0033197"(response to vitamin E)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043200"(response to amino acid)|go:"GO:0045087"(innate immune response)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048678"(response to axon injury)|go:"GO:0051597"(response to methylmercury)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070965"(positive regulation of neutrophil mediated killing of fungus)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071377"(cellular response to glucagon stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:2000552"(negative regulation of T-helper 2 cell cytokine production)|interpro:IPR006035(Ureohydrolase)|interpro:IPR014033(Arginase, subgroup)|go:"GO:0060056"(mammary gland involution)|interpro:IPR020855|interpro:IPR023696|mint:P05089|rcsb pdb:1WVA|rcsb pdb:1WVB|rcsb pdb:2AEB|rcsb pdb:2PHA|rcsb pdb:2PHO|rcsb pdb:2PLL|rcsb pdb:2ZAV|rcsb pdb:3DJ8|rcsb pdb:3E6K|rcsb pdb:3E6V|rcsb pdb:3F80|rcsb pdb:3GMZ|rcsb pdb:3GN0|rcsb pdb:3KV2|rcsb pdb:3LP4|rcsb pdb:3LP7|rcsb pdb:3MFV|rcsb pdb:3MFW|rcsb pdb:3MJL|rcsb pdb:3SJT|rcsb pdb:3SKK|rcsb pdb:3TF3|rcsb pdb:3TH7|rcsb pdb:3THE|rcsb pdb:3THH|rcsb pdb:3THJ|rcsb pdb:4FCI|rcsb pdb:4FCK|rcsb pdb:4GSM|rcsb pdb:4GSV|rcsb pdb:4GSZ|rcsb pdb:4GWC|rcsb pdb:4GWD|rcsb pdb:4HWW|rcsb pdb:4HXQ|rcsb pdb:4IE1|rcsb pdb:6Q92|rcsb pdb:6Q9P|rcsb pdb:6QAF|rcsb pdb:6V7C|rcsb pdb:6V7D|rcsb pdb:6V7E|rcsb pdb:6V7F|reactome:R-HSA-6798695|reactome:R-HSA-70635|uniprotkb:P05089(identity)|entrezgene/locuslink:383(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:b8HHscDekWZdN1S4OxFTA6rjvn89606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q92769 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-301821|uniprotkb:Q5SRI8|uniprotkb:Q5SZ86|uniprotkb:Q8NEH4|uniprotkb:B4DL58|ensembl:ENSP00000430432|uniprotkb:E1P561|uniprotkb:B3KRS5 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:hdac2_human(display_long)|uniprotkb:HDAC2(gene name)|psi-mi:HDAC2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035094"(response to nicotine)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042220"(response to cocaine)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q92769|rcsb pdb:3MAX|rcsb pdb:4LXZ|rcsb pdb:4LY1|rcsb pdb:5IWG|rcsb pdb:5IX0|rcsb pdb:6G3O|rcsb pdb:6WBW|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000196591(gene)|ensembl:ENST00000519065(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|rcsb pdb:6WHN|rcsb pdb:6WHO|rcsb pdb:6WHQ|rcsb pdb:6WHZ|rcsb pdb:6WI3|rcsb pdb:6XDM|rcsb pdb:6XEB|rcsb pdb:6XEC|rcsb pdb:7KBG|rcsb pdb:7KBH|rcsb pdb:7LTG|rcsb pdb:7LTK|rcsb pdb:7LTL|reactome:R-HSA-193670|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9615017|reactome:R-HSA-9619665|reactome:R-HSA-9679191|reactome:R-HSA-983231|rcsb pdb:6WBZ|refseq:NP_001518.3|dip:DIP-24220N|refseq:XP_011534090.1|refseq:XP_016866288.1|uniprotkb:Q92769(identity)|entrezgene/locuslink:3066(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:K4PpGz9E9/TrQZsgvrJuc+uYCn89606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q9C0D4 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-8831278|uniprotkb:Q96LN8|ensembl:ENSP00000317614 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:z518b_human(display_long)|uniprotkb:KIAA1729(gene name synonym)|uniprotkb:ZNF518B(gene name)|psi-mi:ZNF518B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) refseq:XP_016864273.1|refseq:XP_016864274.1|refseq:XP_016864275.1|refseq:NP_444270.2|refseq:XP_005248250.1|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|ensembl:ENSG00000178163(gene)|ensembl:ENST00000326756(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|uniprotkb:Q9C0D4(identity)|entrezgene/locuslink:85460(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:4dw44329P6DHBaeU+tkpIAiWtss9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q09028 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|entrezgene/locuslink:5928(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q13185 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q8N9R8 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-4395514|uniprotkb:Q3SXZ1|uniprotkb:Q3SXZ2|uniprotkb:Q5T163|uniprotkb:Q8N1I4|ensembl:ENSP00000336756 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:scai_human(display_long)|uniprotkb:SCAI(gene name)|psi-mi:SCAI(display_short)|uniprotkb:C9orf126(gene name synonym)|uniprotkb:Suppressor of cancer cell invasion protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) refseq:NP_001138349.1|refseq:NP_775961.2|ensembl:ENSG00000173611(gene)|ensembl:ENST00000336505(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|interpro:IPR016607(Uncharacterised conserved protein UCP013022)|interpro:IPR022709|mint:Q8N9R8|reactome:R-HSA-5663220|uniprotkb:Q8N9R8(identity)|entrezgene/locuslink:286205(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:7rGLwUVUMTIQHugyN2BTnQwluiY9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q96JM2 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-1210359|uniprotkb:Q8N408|uniprotkb:Q5T0T4|intact:EBI-28975500|ensembl:ENSP00000277225 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:zn462_human(display_long)|uniprotkb:ZNF462(gene name)|psi-mi:ZNF462(display_short)|uniprotkb:KIAA1803(gene name synonym)|uniprotkb:Zinc finger PBX1-interacting protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) refseq:NP_067047.4|ensembl:ENSP00000277225|ensembl:ENST00000441147|ensembl:ENSP00000397306|refseq:XP_006717278.1|refseq:XP_006717279.1|dip:DIP-39340N|ensembl:ENSG00000148143(gene)|ensembl:ENST00000277225(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q96JM2|rcsb pdb:1X6F|uniprotkb:Q96JM2(identity)|entrezgene/locuslink:58499(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:ftIOu4wVkBWJw+4aHw+R+nN44Vc9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q8IWI9 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-2815196|uniprotkb:E7ENI0|uniprotkb:F5H7K2|uniprotkb:Q9H9N7|uniprotkb:Q9H8R3|uniprotkb:Q9Y4E9|uniprotkb:Q9UG69|intact:EBI-11143500|intact:EBI-10969960|ensembl:ENSP00000219905|uniprotkb:B9EGR5 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:mgap_human(display_long)|uniprotkb:MGA(gene name)|psi-mi:MGA(display_short)|uniprotkb:KIAA0518(gene name synonym)|uniprotkb:MAD5(gene name synonym)|uniprotkb:MAX dimerization protein 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) refseq:NP_001074010.2|ensembl:ENSP00000219905|ensembl:ENST00000566586|ensembl:ENSP00000456141|ensembl:ENSG00000174197(gene)|ensembl:ENST00000219905(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR018186|interpro:IPR032060|interpro:IPR036638|interpro:IPR036960|interpro:IPR037935|mint:Q8IWI9|reactome:R-HSA-8953750|refseq:NP_001157745.1|dip:DIP-57615N|uniprotkb:Q8IWI9(identity)|entrezgene/locuslink:23269(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:P4lo9EteCvikQQk5kyVkcobitLU9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q5TGY3 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-948813|ensembl:ENSP00000247087|ensembl:ENSP00000363123|ensembl:ENSP00000494394|ensembl:ENSP00000495072|ensembl:ENSP00000495665|ensembl:ENSP00000501218|uniprotkb:Q5TGY4|uniprotkb:Q6PJK1|uniprotkb:Q6ZUQ6|uniprotkb:Q99769|uniprotkb:Q9NUF5 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:ahdc1_human(display_long)|uniprotkb:AHDC1(gene name)|psi-mi:AHDC1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) ensembl:ENSG00000126705(gene)|ensembl:ENST00000247087(transcript)|ensembl:ENST00000374011(transcript)|ensembl:ENST00000642245(transcript)|ensembl:ENST00000642416(transcript)|ensembl:ENST00000644989(transcript)|ensembl:ENST00000673934(transcript)|go:"GO:0003677"(DNA binding)|interpro:IPR032757|interpro:IPR039225|mint:Q5TGY3|refseq:NP_001025053.1|refseq:XP_011539557.1|refseq:XP_011539558.1|refseq:XP_011539559.1|refseq:XP_005245905.1|refseq:XP_005245906.1|refseq:XP_005245907.1|refseq:XP_005245908.1|refseq:XP_005245909.1|uniprotkb:Q5TGY3(identity)|entrezgene/locuslink:27245(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:lYUJEAEhxO204mZnqOd4Vf6K/g89606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:P45973 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|entrezgene/locuslink:23468(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q8ND82 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-8831272|uniprotkb:Q9NXR3|uniprotkb:A8K2V8|ensembl:ENSP00000360017 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:z280c_human(display_long)|uniprotkb:SUHW3(gene name synonym)|uniprotkb:Suppressor of hairy wing homolog 3(gene name synonym)|uniprotkb:ZNF633(gene name synonym)|uniprotkb:Zinc finger protein 633(gene name synonym)|uniprotkb:ZNF280C(gene name)|psi-mi:ZNF280C(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) refseq:NP_060136.1|ensembl:ENSG00000056277(gene)|ensembl:ENST00000370978(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR025243|interpro:IPR036236|mint:Q8ND82|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|uniprotkb:Q8ND82(identity)|entrezgene/locuslink:55609(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:cwFw98IKrHrRV8pySnNy4Tl0g0k9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:P61244 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750|uniprotkb:P61244(identity)|entrezgene/locuslink:4149(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:I5d1d/zT353OsLios95yEITNoWU9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q14186 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|entrezgene/locuslink:7027(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q9UI95 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-77889|ensembl:ENSP00000235310|ensembl:ENSP00000365855|ensembl:ENSP00000365882|uniprotkb:Q5TGW7|uniprotkb:Q9UNA7|uniprotkb:Q9Y6I6|uniprotkb:B3KNE3 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:md2l2_human(display_long)|uniprotkb:MAD2L2(gene name)|psi-mi:MAD2L2(display_short)|uniprotkb:MAD2B(gene name synonym)|uniprotkb:REV7(gene name synonym)|uniprotkb:Mitotic arrest deficient 2-like protein 2(gene name synonym)|uniprotkb:REV7 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) ensembl:ENSG00000116670(gene)|ensembl:ENST00000235310(transcript)|ensembl:ENST00000376667(transcript)|ensembl:ENST00000376692(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007015"(actin filament organization)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0016035"(zeta DNA polymerase complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042772"(DNA damage response, signal transduction resulting in transcription)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR036570|rcsb pdb:3ABD|rcsb pdb:3ABE|rcsb pdb:3VU7|rcsb pdb:4EXT|rcsb pdb:4GK0|rcsb pdb:4GK5|rcsb pdb:5XPT|rcsb pdb:5XPU|rcsb pdb:6BC8|rcsb pdb:6BCD|rcsb pdb:6BI7|rcsb pdb:6K07|rcsb pdb:6K08|rcsb pdb:6KEA|rcsb pdb:6KTO|rcsb pdb:6M7A|rcsb pdb:6M7B|rcsb pdb:6NIF|rcsb pdb:6VE5|rcsb pdb:6WS0|rcsb pdb:6WS5|rcsb pdb:6WW9|rcsb pdb:6WWA|rcsb pdb:7L9P|reactome:R-HSA-110312|reactome:R-HSA-5655862|reactome:R-HSA-5656121|refseq:NP_001120797.1|refseq:NP_006332.3|refseq:XP_011538809.1|uniprotkb:Q9UI95(identity)|entrezgene/locuslink:10459(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:KBeawMhcP3iXUel74pUDl85A/vw9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q06587 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q8N9Z2 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-8831284|uniprotkb:Q7Z756|ensembl:ENSP00000430897 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:cc71l_human(display_long)|uniprotkb:C7orf74(gene name synonym)|uniprotkb:CCDC71L(gene name)|psi-mi:CCDC71L(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) refseq:NP_787080.2|ensembl:ENSG00000253276(gene)|ensembl:ENST00000523505(transcript)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0045600"(positive regulation of fat cell differentiation)|interpro:IPR026695|mint:Q8N9Z2|uniprotkb:Q8N9Z2(identity)|entrezgene/locuslink:168455(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:EZIjQPXDrGzdu/SyF9CrQGxgPuY9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q9H2P0 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-1764854|uniprotkb:E1P5Y2|uniprotkb:O94881|uniprotkb:Q5BKU2|uniprotkb:Q9UG34|intact:EBI-28975656|ensembl:ENSP00000342905|ensembl:ENSP00000360662|ensembl:ENSP00000379346|ensembl:ENSP00000379349|ensembl:ENSP00000483881 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:adnp_human(display_long)|uniprotkb:ADNP(gene name)|psi-mi:ADNP(display_short)|uniprotkb:ADNP1(gene name synonym)|uniprotkb:KIAA0784(gene name synonym)|uniprotkb:Activity-dependent neuroprotective protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) refseq:NP_001269460.1|refseq:NP_001269461.1|refseq:XP_011527049.1|refseq:NP_056154.1|refseq:NP_852107.1|ensembl:ENSP00000342905|ensembl:ENSP00000360662|ensembl:ENSP00000379346|ensembl:ENSP00000379349|ensembl:ENSP00000483881|ensembl:ENSG00000101126(gene)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0033484"(nitric oxide homeostasis)|ensembl:ENST00000349014(transcript)|ensembl:ENST00000371602(transcript)|ensembl:ENST00000396029(transcript)|ensembl:ENST00000396032(transcript)|ensembl:ENST00000621696(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007614"(short-term memory)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019934"(cGMP-mediated signaling)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042277"(peptide binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044849"(estrous cycle)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR038861|mint:Q9H2P0|refseq:XP_016883247.1|refseq:XP_016883248.1|refseq:NP_001334440.1|dip:DIP-47288N|uniprotkb:Q9H2P0(identity)|entrezgene/locuslink:23394(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:QJTl6p2b0Lp7HnHP8sFd5Hv+WGk9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q13111 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-1020839|uniprotkb:Q7Z7K3|uniprotkb:Q9UJY8|uniprotkb:Q6NXG5|intact:EBI-28985893|ensembl:ENSP00000301280 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:caf1a_human(display_long)|uniprotkb:CHAF1A(gene name)|psi-mi:CHAF1A(display_short)|uniprotkb:CAF(gene name synonym)|uniprotkb:CAF1P150(gene name synonym)|uniprotkb:Chromatin assembly factor I p150 subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) refseq:NP_005474.2|ensembl:ENSG00000167670(gene)|ensembl:ENST00000301280(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070087"(chromo shadow domain binding)|interpro:IPR022043|interpro:IPR029091|interpro:IPR029105|mint:Q13111|ensembl:ENSP00000301280|dip:DIP-31135N|uniprotkb:Q13111(identity)|entrezgene/locuslink:10036(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:8ZlQPVvmtN638aK8ZblErN5Bhjo9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q5T3J3 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-473196|ensembl:ENSP00000358778|uniprotkb:Q86XS4|uniprotkb:Q8N3B6|uniprotkb:Q96HT4|uniprotkb:Q9NUM5|uniprotkb:Q9NV32 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:lrif1_human(display_long)|uniprotkb:Receptor-interacting factor 1(gene name synonym)|uniprotkb:LRIF1(gene name)|psi-mi:LRIF1(display_short)|uniprotkb:C1orf103(gene name synonym)|uniprotkb:RIF1(gene name synonym)|uniprotkb:HP1-binding protein enriched in inactive X chromosome protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) ensembl:ENSG00000121931(gene)|ensembl:ENST00000369763(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042974"(retinoic acid receptor binding)|interpro:IPR026191|mint:Q5T3J3|refseq:NP_001006946.1|refseq:NP_060842.3|uniprotkb:Q5T3J3(identity)|entrezgene/locuslink:55791(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:0TZ2ePF1WLfBY9TO/jYZR4GiOKw9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q86XI8 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-2682158|ensembl:ENSP00000331363|uniprotkb:A0A087WWL5 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:zswm9_human(display_long)|uniprotkb:ZSWIM9(gene name)|psi-mi:ZSWIM9(display_short)|uniprotkb:C19orf68(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) refseq:NP_955373.3|ensembl:ENSG00000185453(gene)|ensembl:ENST00000328759(transcript)|interpro:IPR040854|mint:Q86XI8|refseq:XP_006723268.1|uniprotkb:Q86XI8(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:4wOy3iLGFg7lgvbA8nWPUgIgS0w9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q96KQ7 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N|uniprotkb:Q96KQ7(identity)|entrezgene/locuslink:10919(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:P22528 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-1058892|ensembl:ENSP00000306461|uniprotkb:B2R5H7|uniprotkb:P22529|uniprotkb:P22530|uniprotkb:Q5T524 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:spr1b_human(display_long)|uniprotkb:SPRR1B(gene name)|psi-mi:SPRR1B(display_short)|uniprotkb:Small proline-rich protein IB(gene name synonym)|uniprotkb:14.9 kDa pancornulin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) ensembl:ENSG00000169469(gene)|ensembl:ENST00000307098(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031424"(keratinization)|interpro:IPR003302("Cornifin (SPRR)")|mint:P22528|reactome:R-HSA-6809371|refseq:NP_003116.2|uniprotkb:P22528(identity)|entrezgene/locuslink:6699(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:WU0vu+DHdIJm0x40HdcpAdJgdgo9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q9BYE7 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q9BWN1 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-748167|uniprotkb:Q8WTX2|intact:EBI-28975604|ensembl:ENSP00000300835|ensembl:ENSP00000441641 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:prr14_human(display_long)|uniprotkb:PRR14(gene name)|psi-mi:PRR14(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) ensembl:ENSP00000300835|ensembl:ENSP00000441641|refseq:NP_076936.1|refseq:NP_001307393.1|ensembl:ENSG00000156858(gene)|ensembl:ENST00000300835(transcript)|ensembl:ENST00000542965(transcript)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0007517"(muscle organ development)|interpro:IPR026320|interpro:IPR028149|uniprotkb:Q9BWN1(identity)|entrezgene/locuslink:78994(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:09dYdbqpgWweItEVD7Q6qHbEo7Q9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:O75461 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831269|imex:IM-21659-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|ddbj/embl/genbank:BC002609(identity)|entrezgene/locuslink:10951(identity) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 intact-crc:1E8D647FF89FCA0C|rigid:3s1D1/HcJiozBsWrnldltCdVqGA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q9H081 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-1001205|uniprotkb:Q96N24|ensembl:ENSP00000370557|ensembl:ENSP00000461252|ensembl:ENSP00000484532 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:mis12_human(display_long)|uniprotkb:MIS12(gene name)|psi-mi:MIS12(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_001245146.1|refseq:NP_001245147.1|refseq:NP_001245148.1|refseq:NP_001245149.1|refseq:XP_016880522.1|refseq:XP_016880523.1|refseq:XP_016880524.1|refseq:NP_076944.1|ensembl:ENSG00000167842(gene)|ensembl:ENST00000381165(transcript)|ensembl:ENST00000573759(transcript)|ensembl:ENST00000611091(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR008685(Mis12)|mint:Q9H081|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_005256854.1|uniprotkb:Q9H081(identity)|entrezgene/locuslink:79003(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:1qNMwDq3AYOWnRnPa2u3yt7O4109606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q7Z3K3 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-1389308|uniprotkb:O75049|uniprotkb:Q5SZS2|uniprotkb:Q5SZS3|uniprotkb:Q5SZS4|uniprotkb:Q8TDZ7|uniprotkb:Q9Y4X7|uniprotkb:Q3LIC4|uniprotkb:Q5SZS1|intact:EBI-2560449|intact:EBI-11742841|uniprotkb:B4DTP8|uniprotkb:B4DYL9|uniprotkb:B7ZBY5|uniprotkb:E9PM80|intact:EBI-14072025|intact:EBI-17205119|intact:EBI-22321456|intact:EBI-12748249|intact:EBI-16429759|ensembl:ENSP00000271715 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:pogz_human(display_long)|uniprotkb:POGZ(gene name)|psi-mi:POGZ(display_short)|uniprotkb:KIAA0461(gene name synonym)|uniprotkb:Nbla00003(orf name)|uniprotkb:SUHW5(gene name synonym)|uniprotkb:ZNF280E(gene name synonym)|uniprotkb:ZNF635(gene name synonym)|uniprotkb:Suppressor of hairy wing homolog 5(gene name synonym)|uniprotkb:Zinc finger protein 280E(gene name synonym)|uniprotkb:Zinc finger protein 635(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_001181866.1|refseq:NP_001181867.1|refseq:NP_055915.2|refseq:NP_665739.3|refseq:NP_997054.1|refseq:XP_016856234.1|refseq:XP_016856235.1|refseq:XP_016856237.1|refseq:XP_016856238.1|refseq:XP_005245056.1|refseq:XP_005245057.1|refseq:XP_005245058.1|refseq:XP_005245062.1|refseq:XP_005245063.1|dip:DIP-38044N|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSG00000143442(gene)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|ensembl:ENST00000271715(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR004875(CENP-B protein)|interpro:IPR006600(Centromere protein B, helix-turn-helix)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q7Z3K3|rcsb pdb:2E72|rcsb pdb:2N3A|rcsb pdb:6EMP|uniprotkb:Q7Z3K3(identity)|entrezgene/locuslink:23126(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:sCOIY8KsHRQtfcoSA9Tixl9yIsc9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q9H410 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-1001144|uniprotkb:E1P5U9|uniprotkb:Q5JW56|uniprotkb:Q9H8P4|ensembl:ENSP00000362855|ensembl:ENSP00000389810|uniprotkb:Q5JW55|uniprotkb:B4DWT2 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:dsn1_human(display_long)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)|uniprotkb:C20orf172(gene name synonym)|uniprotkb:MIS13(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_001138789.1|refseq:NP_001138787.1|refseq:NP_001138788.1|refseq:NP_079194.3|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-68877|reactome:R-HSA-9648025|rcsb pdb:5LSK|ensembl:ENSG00000149636(gene)|ensembl:ENST00000373750(transcript)|ensembl:ENST00000426836(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000939"(inner kinetochore)|go:"GO:0001650"(fibrillar center)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0051301"(cell division)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|mint:Q9H410|rcsb pdb:5LSI|rcsb pdb:5LSJ|refseq:NP_001138790.1|refseq:XP_006723939.1|uniprotkb:Q9H410(identity)|entrezgene/locuslink:79980(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:cJ0wCtpLS+YkMj83k/SubkpHwuE9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q68DK7 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-2560816|ensembl:ENSP00000381543|uniprotkb:Q69Z03|uniprotkb:Q0VF46|intact:EBI-2654071 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:msl1_human(display_long)|uniprotkb:MSL1(gene name)|psi-mi:MSL1(display_short)|uniprotkb:MSL1L1(gene name synonym)|uniprotkb:Male-specific lethal 1-like 1(gene name synonym)|uniprotkb:Male-specific lethal-1 homolog 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) ensembl:ENSG00000188895(gene)|ensembl:ENST00000398532(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0072487"(MSL complex)|interpro:IPR026711|interpro:IPR029332|interpro:IPR031840|mint:Q68DK7|rcsb pdb:4B7Y|rcsb pdb:4B86|rcsb pdb:4DNC|reactome:R-HSA-3214847|refseq:NP_001012241.1|refseq:XP_005257355.1|dip:DIP-56862N|uniprotkb:Q68DK7(identity)|entrezgene/locuslink:339287(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:sFenPEZNoGtpn1bDFoUzSJBPUBY9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q9H2P0 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-1764854|uniprotkb:E1P5Y2|uniprotkb:O94881|uniprotkb:Q5BKU2|uniprotkb:Q9UG34|intact:EBI-28975656|ensembl:ENSP00000342905|ensembl:ENSP00000360662|ensembl:ENSP00000379346|ensembl:ENSP00000379349|ensembl:ENSP00000483881 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:adnp_human(display_long)|uniprotkb:ADNP(gene name)|psi-mi:ADNP(display_short)|uniprotkb:ADNP1(gene name synonym)|uniprotkb:KIAA0784(gene name synonym)|uniprotkb:Activity-dependent neuroprotective protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_001269460.1|refseq:NP_001269461.1|refseq:XP_011527049.1|refseq:NP_056154.1|refseq:NP_852107.1|ensembl:ENSP00000342905|ensembl:ENSP00000360662|ensembl:ENSP00000379346|ensembl:ENSP00000379349|ensembl:ENSP00000483881|ensembl:ENSG00000101126(gene)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0033484"(nitric oxide homeostasis)|ensembl:ENST00000349014(transcript)|ensembl:ENST00000371602(transcript)|ensembl:ENST00000396029(transcript)|ensembl:ENST00000396032(transcript)|ensembl:ENST00000621696(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007614"(short-term memory)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019934"(cGMP-mediated signaling)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042277"(peptide binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044849"(estrous cycle)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR038861|mint:Q9H2P0|refseq:XP_016883247.1|refseq:XP_016883248.1|refseq:NP_001334440.1|dip:DIP-47288N|uniprotkb:Q9H2P0(identity)|entrezgene/locuslink:23394(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:QJTl6p2b0Lp7HnHP8sFd5Hv+WGk9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q96JM3 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-2560420|uniprotkb:Q8NC88|uniprotkb:B3KU06|uniprotkb:Q6P181|uniprotkb:Q9BST0|ensembl:ENSP00000354730|ensembl:ENSP00000496699 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:chap1_human(display_long)|uniprotkb:CHAMP(gene name synonym)|uniprotkb:CHAMP1(gene name)|psi-mi:CHAMP1(display_short)|uniprotkb:C13orf8(gene name synonym)|uniprotkb:CAMP(gene name synonym)|uniprotkb:KIAA1802(gene name synonym)|uniprotkb:ZNF828(gene name synonym)|uniprotkb:Zinc finger protein 828(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_001157616.1|refseq:NP_001157617.1|refseq:NP_115812.1|ensembl:ENSG00000198824(gene)|ensembl:ENST00000361283(transcript)|ensembl:ENST00000643483(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0016604"(nuclear body)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0046872"(metal ion binding)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0090543"(Flemming body)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR039330|mint:Q96JM3|rcsb pdb:6EKJ|rcsb pdb:6EKL|rcsb pdb:5XPT|rcsb pdb:5XPU|uniprotkb:Q96JM3(identity)|entrezgene/locuslink:283489(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:Di1yMiufHKsy384vPjOgdncmQXw9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q969R5 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750|uniprotkb:Q969R5(identity)|entrezgene/locuslink:83746(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q8IY57 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|entrezgene/locuslink:10138(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q96CS4 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-4395570|uniprotkb:Q658J5|ensembl:ENSP00000287461 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:zn689_human(display_long)|uniprotkb:ZNF689(gene name)|psi-mi:ZNF689(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_612456.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|ensembl:ENSG00000156853(gene)|ensembl:ENST00000287461(transcript)|uniprotkb:Q96CS4(identity)|entrezgene/locuslink:115509(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:Pu6f7CUHQ9L6Ovrx4lDRoWm5mGA9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q13263 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-78139|uniprotkb:O00677|ensembl:ENSP00000253024|uniprotkb:Q7Z632|uniprotkb:Q93040|uniprotkb:Q96IM1 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:tif1b_human(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6QAJ|rcsb pdb:6QU1|reactome:R-HSA-212436|reactome:R-HSA-3899300|reactome:R-HSA-9609690|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q13263|rcsb pdb:1FP0|rcsb pdb:2RO1|rcsb pdb:2YVR|rcsb pdb:6H3A|rcsb pdb:6I9H|refseq:NP_005753.1|dip:DIP-30891N|uniprotkb:Q13263(identity)|entrezgene/locuslink:10155(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q5T3J3 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-473196|ensembl:ENSP00000358778|uniprotkb:Q86XS4|uniprotkb:Q8N3B6|uniprotkb:Q96HT4|uniprotkb:Q9NUM5|uniprotkb:Q9NV32 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:lrif1_human(display_long)|uniprotkb:Receptor-interacting factor 1(gene name synonym)|uniprotkb:LRIF1(gene name)|psi-mi:LRIF1(display_short)|uniprotkb:C1orf103(gene name synonym)|uniprotkb:RIF1(gene name synonym)|uniprotkb:HP1-binding protein enriched in inactive X chromosome protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) ensembl:ENSG00000121931(gene)|ensembl:ENST00000369763(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042974"(retinoic acid receptor binding)|interpro:IPR026191|mint:Q5T3J3|refseq:NP_001006946.1|refseq:NP_060842.3|uniprotkb:Q5T3J3(identity)|entrezgene/locuslink:55791(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:0TZ2ePF1WLfBY9TO/jYZR4GiOKw9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q13129 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-958266|uniprotkb:Q14CQ1|uniprotkb:Q9NU60|ensembl:ENSP00000361857 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:rlf_human(display_long)|uniprotkb:RLF(gene name)|psi-mi:RLF(display_short)|uniprotkb:Rearranged L-myc fusion gene protein(gene name synonym)|uniprotkb:Zn-15-related protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_036553.2|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|ensembl:ENSG00000117000(gene)|ensembl:ENST00000372771(transcript)|uniprotkb:Q13129(identity)|entrezgene/locuslink:6018(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:nWnF2P2Bh0uPJSAL6a5//1MxOl09606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q6N043 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-4395404|uniprotkb:A1L495|uniprotkb:B2RMT6|uniprotkb:Q6MZM6|uniprotkb:Q6N085|uniprotkb:Q9H0U5|uniprotkb:Q9HCI8|uniprotkb:Q9NXS0|uniprotkb:Q6P2R6|uniprotkb:Q7Z6J5|intact:EBI-28970145|ensembl:ENSP00000267807 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:z280d_human(display_long)|uniprotkb:ZNF280D(gene name)|psi-mi:ZNF280D(display_short)|uniprotkb:KIAA1584(gene name synonym)|uniprotkb:SUHW4(gene name synonym)|uniprotkb:ZNF634(gene name synonym)|uniprotkb:Suppressor of hairy wing homolog 4(gene name synonym)|uniprotkb:Zinc finger protein 634(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) ensembl:ENSP00000267807|ensembl:ENST00000558067|ensembl:ENSP00000454173|ensembl:ENST00000558320|ensembl:ENSP00000453706|ensembl:ENST00000559237|ensembl:ENSP00000454111|ensembl:ENST00000560002|ensembl:ENSP00000453636|refseq:XP_011520004.1|refseq:NP_001002843.1|refseq:NP_060131.2|refseq:NP_001275517.1|refseq:NP_001002844.1|refseq:NP_001275518.1|refseq:XP_016877833.1|refseq:XP_016877834.1|ensembl:ENSG00000137871(gene)|ensembl:ENST00000267807(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR025243|interpro:IPR036236|mint:Q6N043|uniprotkb:Q6N043(identity)|entrezgene/locuslink:54816(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:BYkVW7yPK+LxorbA2quTgne0Txs9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q9BQF6 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-766251|uniprotkb:Q7Z3F4|uniprotkb:Q96PS5|uniprotkb:Q9C0F6|uniprotkb:Q9HBT5|uniprotkb:A1L3A5|uniprotkb:A8MW39|uniprotkb:B7WNW8|ensembl:ENSP00000377655 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:senp7_human(display_long)|uniprotkb:SUMO-1-specific protease 2(gene name synonym)|uniprotkb:Sentrin/SUMO-specific protease SENP7(gene name synonym)|uniprotkb:SENP7(gene name)|psi-mi:SENP7(display_short)|uniprotkb:KIAA1707(gene name synonym)|uniprotkb:SSP2(gene name synonym)|uniprotkb:SUSP2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_001070671.1|refseq:NP_001269730.1|refseq:NP_001269731.1|refseq:NP_001269732.1|refseq:NP_001269733.1|refseq:NP_065705.3|refseq:XP_016862414.1|ensembl:ENSG00000138468(gene)|ensembl:ENST00000394095(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016926"(protein desumoylation)|go:"GO:0070139"(SUMO-specific endopeptidase activity)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|rcsb pdb:3EAY|interpro:IPR038765|uniprotkb:Q9BQF6(identity)|entrezgene/locuslink:57337(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:dLL7YHqSkqW17N+IHtiDf0yC07Q9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:O43463 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-349968|uniprotkb:Q53G60|uniprotkb:Q6FHK6|ensembl:ENSP00000365877|uniprotkb:B2R6E8|uniprotkb:B4DST0 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:suv91_human(display_long)|uniprotkb:SUV39H1(gene name)|psi-mi:SUV39H1(display_short)|uniprotkb:SUV39H(gene name synonym)|uniprotkb:KMT1A(gene name synonym)|uniprotkb:Suppressor of variegation 3-9 homolog 1(gene name synonym)|uniprotkb:Position-effect variegation 3-9 homolog(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_003164.1|ensembl:ENSG00000101945(gene)|ensembl:ENST00000376687(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0006364"(rRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|mint:O43463|rcsb pdb:3MTS|reactome:R-HSA-3214841|reactome:R-HSA-427359|refseq:NP_001269095.1|dip:DIP-32589N|uniprotkb:O43463(identity)|entrezgene/locuslink:6839(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:dbenLwo5hxhGzFD4sLNOVUveElM9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:P45973 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|entrezgene/locuslink:23468(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:P63167 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-349105|uniprotkb:Q15701|ensembl:ENSP00000242577|ensembl:ENSP00000376296|ensembl:ENSP00000376297|ensembl:ENSP00000446614|ensembl:ENSP00000447907 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:dyl1_human(display_long)|uniprotkb:DYNLL1(gene name)|psi-mi:DYNLL1(display_short)|uniprotkb:DLC1(gene name synonym)|uniprotkb:DNCLC1(gene name synonym)|uniprotkb:HDLC1(gene name synonym)|uniprotkb:Dynein light chain LC8-type 1(gene name synonym)|uniprotkb:8 kDa dynein light chain(gene name synonym)|uniprotkb:Protein inhibitor of neuronal nitric oxide synthase(gene name synonym)|uniprotkb:DNCL1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_001032583.1|refseq:NP_001032584.1|refseq:NP_003737.1|go:"GO:0072686"(mitotic spindle)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:P63167|rcsb pdb:1CMI|rcsb pdb:3ZKE|rcsb pdb:3ZKF|rcsb pdb:6GZJ|rcsb pdb:6GZL|rcsb pdb:6RLB|rcsb pdb:6SC2|rcsb pdb:7D35|reactome:R-HSA-111446|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|go:"GO:0000776"(kinetochore)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0005829"(cytosol)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007286"(spermatid development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030286"(dynein complex)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|ensembl:ENSG00000088986(gene)|ensembl:ENST00000242577(transcript)|ensembl:ENST00000392508(transcript)|ensembl:ENST00000392509(transcript)|ensembl:ENST00000548342(transcript)|ensembl:ENST00000549989(transcript)|dip:DIP-33150N|uniprotkb:P63167(identity)|entrezgene/locuslink:8655(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:Bra4LfaqYPMyo6xX9RD6G7Rdv809606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:P18077 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-353383|uniprotkb:Q08ES9|uniprotkb:Q9BVN7|ensembl:ENSP00000393393|ensembl:ENSP00000495672 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:rl35a_human(display_long)|uniprotkb:RPL35A(gene name)|psi-mi:RPL35A(display_short)|uniprotkb:Cell growth-inhibiting gene 33 protein(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL33(gene name synonym)|uniprotkb:GIG33(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_000987.2|refseq:NP_001303240.1|ensembl:ENST00000647248(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001780(Ribosomal protein L35Ae)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR018266|interpro:IPR038661|mint:P18077|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|ensembl:ENSG00000182899(gene)|ensembl:ENST00000448864(transcript)|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|uniprotkb:P18077(identity)|entrezgene/locuslink:6165(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:fnUlL17LsiOp3lSkKNsoYO74IQQ9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q09028 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|entrezgene/locuslink:5928(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q96JM2 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-1210359|uniprotkb:Q8N408|uniprotkb:Q5T0T4|intact:EBI-28975500|ensembl:ENSP00000277225 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:zn462_human(display_long)|uniprotkb:ZNF462(gene name)|psi-mi:ZNF462(display_short)|uniprotkb:KIAA1803(gene name synonym)|uniprotkb:Zinc finger PBX1-interacting protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_067047.4|ensembl:ENSP00000277225|ensembl:ENST00000441147|ensembl:ENSP00000397306|refseq:XP_006717278.1|refseq:XP_006717279.1|dip:DIP-39340N|ensembl:ENSG00000148143(gene)|ensembl:ENST00000277225(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q96JM2|rcsb pdb:1X6F|uniprotkb:Q96JM2(identity)|entrezgene/locuslink:58499(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:ftIOu4wVkBWJw+4aHw+R+nN44Vc9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q9H9B1 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-766087|uniprotkb:Q8TCN7|uniprotkb:Q96F53|uniprotkb:Q96JF1|uniprotkb:Q96KH4|uniprotkb:B1AQ58|uniprotkb:B1AQ59|uniprotkb:Q86X08|ensembl:ENSP00000417980 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:ehmt1_human(display_long)|uniprotkb:KMT1D(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 5(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 1(gene name synonym)|uniprotkb:G9a-like protein 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1D(gene name synonym)|uniprotkb:EHMT1(gene name)|psi-mi:EHMT1(display_short)|uniprotkb:EUHMTASE1(gene name synonym)|uniprotkb:KIAA1876(gene name synonym)|uniprotkb:GLP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_001138999.1|refseq:NP_079033.4|ensembl:ENST00000371394|ensembl:ENSP00000485945|ensembl:ENSP00000417980|ensembl:ENST00000462484|ensembl:ENSP00000417328|dip:DIP-34585N|ensembl:ENSG00000181090(gene)|ensembl:ENST00000460843(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016604"(nuclear body)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038035|interpro:IPR043550|mint:Q9H9B1|rcsb pdb:2IGQ|rcsb pdb:2RFI|rcsb pdb:3B7B|rcsb pdb:3B95|rcsb pdb:3FPD|rcsb pdb:3HNA|rcsb pdb:3MO0|rcsb pdb:3MO2|rcsb pdb:3MO5|rcsb pdb:3SW9|rcsb pdb:3SWC|rcsb pdb:4I51|rcsb pdb:5TTG|rcsb pdb:5TUZ|rcsb pdb:5V9J|rcsb pdb:5VSD|rcsb pdb:5VSF|rcsb pdb:6BY9|rcsb pdb:6MBO|rcsb pdb:6MBP|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-6804760|reactome:R-HSA-8853884|reactome:R-HSA-8953750|uniprotkb:Q9H9B1(identity)|entrezgene/locuslink:79813(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:4L6QOGSsRPi8hDjS2/BYShjpnf89606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:P22528 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-1058892|ensembl:ENSP00000306461|uniprotkb:B2R5H7|uniprotkb:P22529|uniprotkb:P22530|uniprotkb:Q5T524 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:spr1b_human(display_long)|uniprotkb:SPRR1B(gene name)|psi-mi:SPRR1B(display_short)|uniprotkb:Small proline-rich protein IB(gene name synonym)|uniprotkb:14.9 kDa pancornulin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) ensembl:ENSG00000169469(gene)|ensembl:ENST00000307098(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031424"(keratinization)|interpro:IPR003302("Cornifin (SPRR)")|mint:P22528|reactome:R-HSA-6809371|refseq:NP_003116.2|uniprotkb:P22528(identity)|entrezgene/locuslink:6699(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:WU0vu+DHdIJm0x40HdcpAdJgdgo9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:P61244 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750|uniprotkb:P61244(identity)|entrezgene/locuslink:4149(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:I5d1d/zT353OsLios95yEITNoWU9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:P05089 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-2513844|uniprotkb:Q5JWT6|uniprotkb:Q5JWT5|uniprotkb:Q9BS50|uniprotkb:Q8TE72|uniprotkb:A6NEA0|ensembl:ENSP00000357066 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:argi1_human(display_long)|uniprotkb:ARG1(gene name)|psi-mi:ARG1(display_short)|uniprotkb:Type I arginase(gene name synonym)|uniprotkb:Liver-type arginase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_000036.2|refseq:NP_001231367.1|ensembl:ENSG00000118520(gene)|ensembl:ENST00000368087(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0001889"(liver development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004053"(arginase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006527"(arginine catabolic process)|go:"GO:0007568"(aging)|go:"GO:0009635"(response to herbicide)|go:"GO:0010042"(response to manganese ion)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010963"|go:"GO:0014075"(response to amine)|go:"GO:0019547"(arginine catabolic process to ornithine)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030324"(lung development)|go:"GO:0032964"(collagen biosynthetic process)|go:"GO:0033189"(response to vitamin A)|go:"GO:0033197"(response to vitamin E)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043200"(response to amino acid)|go:"GO:0045087"(innate immune response)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048678"(response to axon injury)|go:"GO:0051597"(response to methylmercury)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070965"(positive regulation of neutrophil mediated killing of fungus)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071377"(cellular response to glucagon stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:2000552"(negative regulation of T-helper 2 cell cytokine production)|interpro:IPR006035(Ureohydrolase)|interpro:IPR014033(Arginase, subgroup)|go:"GO:0060056"(mammary gland involution)|interpro:IPR020855|interpro:IPR023696|mint:P05089|rcsb pdb:1WVA|rcsb pdb:1WVB|rcsb pdb:2AEB|rcsb pdb:2PHA|rcsb pdb:2PHO|rcsb pdb:2PLL|rcsb pdb:2ZAV|rcsb pdb:3DJ8|rcsb pdb:3E6K|rcsb pdb:3E6V|rcsb pdb:3F80|rcsb pdb:3GMZ|rcsb pdb:3GN0|rcsb pdb:3KV2|rcsb pdb:3LP4|rcsb pdb:3LP7|rcsb pdb:3MFV|rcsb pdb:3MFW|rcsb pdb:3MJL|rcsb pdb:3SJT|rcsb pdb:3SKK|rcsb pdb:3TF3|rcsb pdb:3TH7|rcsb pdb:3THE|rcsb pdb:3THH|rcsb pdb:3THJ|rcsb pdb:4FCI|rcsb pdb:4FCK|rcsb pdb:4GSM|rcsb pdb:4GSV|rcsb pdb:4GSZ|rcsb pdb:4GWC|rcsb pdb:4GWD|rcsb pdb:4HWW|rcsb pdb:4HXQ|rcsb pdb:4IE1|rcsb pdb:6Q92|rcsb pdb:6Q9P|rcsb pdb:6QAF|rcsb pdb:6V7C|rcsb pdb:6V7D|rcsb pdb:6V7E|rcsb pdb:6V7F|reactome:R-HSA-6798695|reactome:R-HSA-70635|uniprotkb:P05089(identity)|entrezgene/locuslink:383(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:b8HHscDekWZdN1S4OxFTA6rjvn89606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q9BYE7 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:P06400 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-491274|uniprotkb:P78499|uniprotkb:Q5VW46|uniprotkb:Q8IZL4|uniprotkb:A8K5E3|ensembl:ENSP00000267163 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:rb_human(display_long)|uniprotkb:pRb(gene name synonym)|uniprotkb:pp110(gene name synonym)|uniprotkb:p105-Rb(gene name synonym)|uniprotkb:RB1(gene name)|psi-mi:RB1(display_short)|uniprotkb:p110-RB1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) go:"GO:1903055"(positive regulation of extracellular matrix organization)|refseq:NP_000312.2|go:"GO:1904028"(positive regulation of collagen fibril organization)|go:"GO:1904761"(negative regulation of myofibroblast differentiation)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR036915|mint:P06400|rcsb pdb:1AD6|rcsb pdb:1GH6|rcsb pdb:1GUX|rcsb pdb:1H25|rcsb pdb:1N4M|rcsb pdb:1O9K|rcsb pdb:1PJM|rcsb pdb:2AZE|rcsb pdb:2QDJ|rcsb pdb:2R7G|rcsb pdb:3N5U|rcsb pdb:3POM|rcsb pdb:4CRI|rcsb pdb:4ELJ|rcsb pdb:4ELL|reactome:R-HSA-113501|reactome:R-HSA-174178|reactome:R-HSA-2299718|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-69200|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8940973|reactome:R-HSA-9661069|reactome:R-HSA-9661070|reactome:R-HSA-9682706|reactome:R-HSA-9687136|reactome:R-HSA-9694686|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016605"(PML body)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0019900"(kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0031175"(neuron projection development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034088"(maintenance of mitotic sister chromatid cohesion)|go:"GO:0034349"(glial cell apoptotic process)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042551"(neuron maturation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0071922"(regulation of cohesin loading)|go:"GO:0071930"(negative regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0090230"(regulation of centromere complex assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902948"(negative regulation of tau-protein kinase activity)|ensembl:ENSG00000139687(gene)|ensembl:ENST00000267163(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|dip:DIP-582N|uniprotkb:P06400(identity)|entrezgene/locuslink:5925(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:xidCNX96KlQzu160polvT61k4Zw9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q6P1K2 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-713832|uniprotkb:Q5TCJ8|uniprotkb:Q5TCJ9|uniprotkb:Q5TCK3|uniprotkb:Q69YZ9|uniprotkb:Q6PHR4|uniprotkb:Q86VJ6|uniprotkb:Q8N4T6|uniprotkb:Q9UBQ3|uniprotkb:A8K0C5|intact:EBI-2554676|uniprotkb:Q5TCK0|ensembl:ENSP00000357260|uniprotkb:Q5TCK1|uniprotkb:Q6ZVE6 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:pmf1_human(display_long)|uniprotkb:PMF1(gene name)|psi-mi:PMF1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) ensembl:ENSG00000160783(gene)|ensembl:ENST00000368277(transcript)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0051301"(cell division)|interpro:IPR007128(Nnf1)|mint:Q6P1K2|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001186582.1|refseq:NP_001186583.1|refseq:NP_001186590.1|refseq:NP_001186592.1|refseq:NP_009152.2|uniprotkb:Q6P1K2(identity)|entrezgene/locuslink:11243(identity)|entrezgene/locuslink:100527963(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:76xPGmFgI3Pt1gsZMb3aD4hpPWM9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q9H582 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-2560435|uniprotkb:Q7LG67|uniprotkb:Q5TCC0|uniprotkb:Q6PI06|uniprotkb:Q9ULJ9|uniprotkb:A2RU71|uniprotkb:Q2TAM0|uniprotkb:Q6P446|uniprotkb:Q6BEP7|ensembl:ENSP00000337008|ensembl:ENSP00000359469 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:zn644_human(display_long)|uniprotkb:ZNF644(gene name)|psi-mi:ZNF644(display_short)|uniprotkb:KIAA1221(gene name synonym)|uniprotkb:ZEP2(gene name synonym)|uniprotkb:Zinc finger motif enhancer-binding protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_057704.2|refseq:NP_115562.3|refseq:NP_958357.1|refseq:XP_016857977.1|refseq:XP_016857978.1|refseq:XP_016857979.1|refseq:XP_016857980.1|refseq:XP_016857981.1|refseq:XP_016857982.1|refseq:XP_016857983.1|ensembl:ENSG00000122482(gene)|ensembl:ENST00000337393(transcript)|ensembl:ENST00000370440(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9H582|uniprotkb:Q9H582(identity)|entrezgene/locuslink:84146(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:16MjfkV6aoDArzVV5Qi0K2HI2lg9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q96IY1 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-2554690|uniprotkb:Q9H2M5|uniprotkb:Q5SY75|uniprotkb:Q9Y415|uniprotkb:Q9NRN8|ensembl:ENSP00000355944|uniprotkb:E7ETD5 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:nsl1_human(display_long)|uniprotkb:C1orf48(gene name synonym)|uniprotkb:DC8(orf name)|uniprotkb:DC31(orf name)|uniprotkb:MIS14(orf name)|uniprotkb:NSL1(gene name)|psi-mi:NSL1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_056286.3|ensembl:ENSG00000117697(gene)|ensembl:ENST00000366977(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|go:"GO:0051301"(cell division)|interpro:IPR013950(Kinetochore Mis14)|mint:Q96IY1|rcsb pdb:4NF9|rcsb pdb:5LSI|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-2500257|reactome:R-HSA-9648025|refseq:NP_001036014.1|uniprotkb:Q96IY1(identity)|entrezgene/locuslink:25936(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:w4K2MEHLfZvFECNhtDanXWF0LQk9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q9C0D4 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-8831278|uniprotkb:Q96LN8|ensembl:ENSP00000317614 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:z518b_human(display_long)|uniprotkb:KIAA1729(gene name synonym)|uniprotkb:ZNF518B(gene name)|psi-mi:ZNF518B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:XP_016864273.1|refseq:XP_016864274.1|refseq:XP_016864275.1|refseq:NP_444270.2|refseq:XP_005248250.1|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|ensembl:ENSG00000178163(gene)|ensembl:ENST00000326756(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|uniprotkb:Q9C0D4(identity)|entrezgene/locuslink:85460(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:4dw44329P6DHBaeU+tkpIAiWtss9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q5TGY3 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-948813|ensembl:ENSP00000247087|ensembl:ENSP00000363123|ensembl:ENSP00000494394|ensembl:ENSP00000495072|ensembl:ENSP00000495665|ensembl:ENSP00000501218|uniprotkb:Q5TGY4|uniprotkb:Q6PJK1|uniprotkb:Q6ZUQ6|uniprotkb:Q99769|uniprotkb:Q9NUF5 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:ahdc1_human(display_long)|uniprotkb:AHDC1(gene name)|psi-mi:AHDC1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) ensembl:ENSG00000126705(gene)|ensembl:ENST00000247087(transcript)|ensembl:ENST00000374011(transcript)|ensembl:ENST00000642245(transcript)|ensembl:ENST00000642416(transcript)|ensembl:ENST00000644989(transcript)|ensembl:ENST00000673934(transcript)|go:"GO:0003677"(DNA binding)|interpro:IPR032757|interpro:IPR039225|mint:Q5TGY3|refseq:NP_001025053.1|refseq:XP_011539557.1|refseq:XP_011539558.1|refseq:XP_011539559.1|refseq:XP_005245905.1|refseq:XP_005245906.1|refseq:XP_005245907.1|refseq:XP_005245908.1|refseq:XP_005245909.1|uniprotkb:Q5TGY3(identity)|entrezgene/locuslink:27245(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:lYUJEAEhxO204mZnqOd4Vf6K/g89606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q86XI8 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-2682158|ensembl:ENSP00000331363|uniprotkb:A0A087WWL5 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:zswm9_human(display_long)|uniprotkb:ZSWIM9(gene name)|psi-mi:ZSWIM9(display_short)|uniprotkb:C19orf68(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_955373.3|ensembl:ENSG00000185453(gene)|ensembl:ENST00000328759(transcript)|interpro:IPR040854|mint:Q86XI8|refseq:XP_006723268.1|uniprotkb:Q86XI8(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:4wOy3iLGFg7lgvbA8nWPUgIgS0w9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q96KQ7 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N|uniprotkb:Q96KQ7(identity)|entrezgene/locuslink:10919(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:P83916 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|entrezgene/locuslink:10951(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q9UI95 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-77889|ensembl:ENSP00000235310|ensembl:ENSP00000365855|ensembl:ENSP00000365882|uniprotkb:Q5TGW7|uniprotkb:Q9UNA7|uniprotkb:Q9Y6I6|uniprotkb:B3KNE3 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:md2l2_human(display_long)|uniprotkb:MAD2L2(gene name)|psi-mi:MAD2L2(display_short)|uniprotkb:MAD2B(gene name synonym)|uniprotkb:REV7(gene name synonym)|uniprotkb:Mitotic arrest deficient 2-like protein 2(gene name synonym)|uniprotkb:REV7 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) ensembl:ENSG00000116670(gene)|ensembl:ENST00000235310(transcript)|ensembl:ENST00000376667(transcript)|ensembl:ENST00000376692(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007015"(actin filament organization)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0016035"(zeta DNA polymerase complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042772"(DNA damage response, signal transduction resulting in transcription)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR036570|rcsb pdb:3ABD|rcsb pdb:3ABE|rcsb pdb:3VU7|rcsb pdb:4EXT|rcsb pdb:4GK0|rcsb pdb:4GK5|rcsb pdb:5XPT|rcsb pdb:5XPU|rcsb pdb:6BC8|rcsb pdb:6BCD|rcsb pdb:6BI7|rcsb pdb:6K07|rcsb pdb:6K08|rcsb pdb:6KEA|rcsb pdb:6KTO|rcsb pdb:6M7A|rcsb pdb:6M7B|rcsb pdb:6NIF|rcsb pdb:6VE5|rcsb pdb:6WS0|rcsb pdb:6WS5|rcsb pdb:6WW9|rcsb pdb:6WWA|rcsb pdb:7L9P|reactome:R-HSA-110312|reactome:R-HSA-5655862|reactome:R-HSA-5656121|refseq:NP_001120797.1|refseq:NP_006332.3|refseq:XP_011538809.1|uniprotkb:Q9UI95(identity)|entrezgene/locuslink:10459(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:KBeawMhcP3iXUel74pUDl85A/vw9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q9BWN1 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-748167|uniprotkb:Q8WTX2|intact:EBI-28975604|ensembl:ENSP00000300835|ensembl:ENSP00000441641 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:prr14_human(display_long)|uniprotkb:PRR14(gene name)|psi-mi:PRR14(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) ensembl:ENSP00000300835|ensembl:ENSP00000441641|refseq:NP_076936.1|refseq:NP_001307393.1|ensembl:ENSG00000156858(gene)|ensembl:ENST00000300835(transcript)|ensembl:ENST00000542965(transcript)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0007517"(muscle organ development)|interpro:IPR026320|interpro:IPR028149|uniprotkb:Q9BWN1(identity)|entrezgene/locuslink:78994(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:09dYdbqpgWweItEVD7Q6qHbEo7Q9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q14202 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-2556139|uniprotkb:O15089|ensembl:ENSP00000322845|uniprotkb:D3DVV3|uniprotkb:Q96E26 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:zmym3_human(display_long)|uniprotkb:DXS6673E(gene name synonym)|uniprotkb:KIAA0385(gene name synonym)|uniprotkb:ZNF261(gene name synonym)|uniprotkb:Zinc finger protein 261(gene name synonym)|uniprotkb:ZMYM3(gene name)|psi-mi:ZMYM3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_001164633.1|refseq:NP_005087.1|refseq:NP_963893.1|refseq:XP_011529364.1|ensembl:ENSG00000147130(gene)|ensembl:ENST00000314425(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022604"(regulation of cell morphogenesis)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR021893|mint:Q14202|refseq:NP_001164634.1|refseq:XP_005262366.1|refseq:XP_005262367.1|uniprotkb:Q14202(identity)|entrezgene/locuslink:9203(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:pNPpauiC3Qk1EB3mevtM9L/+g0A9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q92769 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-301821|uniprotkb:Q5SRI8|uniprotkb:Q5SZ86|uniprotkb:Q8NEH4|uniprotkb:B4DL58|ensembl:ENSP00000430432|uniprotkb:E1P561|uniprotkb:B3KRS5 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:hdac2_human(display_long)|uniprotkb:HDAC2(gene name)|psi-mi:HDAC2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035094"(response to nicotine)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042220"(response to cocaine)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q92769|rcsb pdb:3MAX|rcsb pdb:4LXZ|rcsb pdb:4LY1|rcsb pdb:5IWG|rcsb pdb:5IX0|rcsb pdb:6G3O|rcsb pdb:6WBW|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000196591(gene)|ensembl:ENST00000519065(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|rcsb pdb:6WHN|rcsb pdb:6WHO|rcsb pdb:6WHQ|rcsb pdb:6WHZ|rcsb pdb:6WI3|rcsb pdb:6XDM|rcsb pdb:6XEB|rcsb pdb:6XEC|rcsb pdb:7KBG|rcsb pdb:7KBH|rcsb pdb:7LTG|rcsb pdb:7LTK|rcsb pdb:7LTL|reactome:R-HSA-193670|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9615017|reactome:R-HSA-9619665|reactome:R-HSA-9679191|reactome:R-HSA-983231|rcsb pdb:6WBZ|refseq:NP_001518.3|dip:DIP-24220N|refseq:XP_011534090.1|refseq:XP_016866288.1|uniprotkb:Q92769(identity)|entrezgene/locuslink:3066(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:K4PpGz9E9/TrQZsgvrJuc+uYCn89606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:O75461 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:O14950 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-1642165|uniprotkb:D3DUH6|intact:EBI-2826593|uniprotkb:Q7Z5Z4|uniprotkb:Q13182|ensembl:ENSP00000237500|ensembl:ENSP00000383037|ensembl:ENSP00000463559|ensembl:ENSP00000464464|ensembl:ENSP00000496809 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:ml12b_human(display_long)|uniprotkb:MYL12B(gene name)|psi-mi:MYL12B(display_short)|uniprotkb:MRLC2(gene name synonym)|uniprotkb:Myosin regulatory light chain 2-B, smooth muscle isoform(gene name synonym)|uniprotkb:MLC-2A(gene name synonym)|uniprotkb:SHUJUN-1(gene name synonym)|uniprotkb:MYLC2B(gene name synonym)|uniprotkb:Myosin regulatory light chain MRLC2(gene name synonym)|uniprotkb:Myosin regulatory light chain 20 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_001138416.1|refseq:NP_001138417.1|refseq:NP_291024.1|refseq:NP_001289978.1|ensembl:ENSG00000118680(gene)|ensembl:ENST00000237500(transcript)|ensembl:ENST00000400175(transcript)|ensembl:ENST00000581193(transcript)|ensembl:ENST00000584539(transcript)|ensembl:ENST00000648965(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016460"(myosin II complex)|go:"GO:0030018"(Z disc)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR015070(Region of unknown function DUF1880)|interpro:IPR018247|mint:O14950|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|uniprotkb:O14950(identity)|entrezgene/locuslink:103910(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:5jOP3J5TW0eU9zwalQ2S4Oist4k9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q6AHZ1 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-2813764|uniprotkb:O15044|uniprotkb:A0PJI5|uniprotkb:Q32MP4|ensembl:ENSP00000479684|ensembl:ENSP00000481657|ensembl:ENSP00000485614 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:z518a_human(display_long)|uniprotkb:ZNF518A(gene name)|psi-mi:ZNF518A(display_short)|uniprotkb:KIAA0335(gene name synonym)|uniprotkb:ZNF518(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:XP_011538715.1|refseq:XP_011538717.1|refseq:XP_011538720.1|refseq:XP_011538721.1|refseq:XP_011538708.1|refseq:XP_011538722.1|refseq:XP_011538710.1|refseq:XP_011538712.1|refseq:XP_011538714.1|refseq:NP_055618.2|refseq:NP_001317661.1|refseq:NP_001317662.1|refseq:NP_001317663.1|refseq:NP_001317664.1|refseq:NP_001317665.1|refseq:NP_001317666.1|refseq:NP_001317667.1|refseq:XP_016872475.1|refseq:XP_016872478.1|refseq:XP_016872481.1|refseq:XP_016872483.1|refseq:XP_016872486.1|refseq:XP_016872487.1|refseq:XP_016872488.1|ensembl:ENSG00000177853(gene)|ensembl:ENST00000316045(transcript)|ensembl:ENST00000614149(transcript)|ensembl:ENST00000624776(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027760|interpro:IPR036236|refseq:NP_001265453.1|refseq:NP_001265454.1|refseq:NP_001265455.1|uniprotkb:Q6AHZ1(identity)|entrezgene/locuslink:9849(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:UjGW18sLz9JzoM8943TK/3P5VpY9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:P61964 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|entrezgene/locuslink:11091(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:O75556 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-8830751|ensembl:ENSP00000244930 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:sg2a1_human(display_long)|uniprotkb:LIPHC(gene name synonym)|uniprotkb:Lacryglobin(gene name synonym)|uniprotkb:Lipophilin-C(gene name synonym)|uniprotkb:MGB2(gene name synonym)|uniprotkb:Mammaglobin-2(gene name synonym)|uniprotkb:Secretoglobin family 2A member 1(gene name synonym)|uniprotkb:UGB3(gene name synonym)|uniprotkb:SCGB2A1(gene name)|psi-mi:SCGB2A1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_002398.1|ensembl:ENSG00000124939(gene)|ensembl:ENST00000244930(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0030521"(androgen receptor signaling pathway)|interpro:IPR016126(Secretoglobin)|interpro:IPR035960|uniprotkb:O75556(identity)|entrezgene/locuslink:4246(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:w+3NKAb7Len68q3aS4Re1qKbOac9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q13112 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-1052944|uniprotkb:Q99548|ensembl:ENSP00000315700 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:caf1b_human(display_long)|uniprotkb:Chromatin assembly factor I p60 subunit(gene name synonym)|uniprotkb:M-phase phosphoprotein 7(gene name synonym)|uniprotkb:CHAF1B(gene name)|psi-mi:CHAF1B(display_short)|uniprotkb:CAF1A(gene name synonym)|uniprotkb:CAF1P60(gene name synonym)|uniprotkb:MPHOSPH7(gene name synonym)|uniprotkb:MPP7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_005432.1|dip:DIP-29243N|ensembl:ENSG00000159259(gene)|ensembl:ENST00000314103(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR029129|interpro:IPR036322|mint:Q13112|refseq:XP_016883966.1|refseq:XP_016883967.1|uniprotkb:Q13112(identity)|entrezgene/locuslink:8208(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:VVbW9mpUGYMRPxvlEk9FERHIsJs9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q8N488 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|uniprotkb:Q8N488(identity)|entrezgene/locuslink:23429(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q8N9Z2 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-8831284|uniprotkb:Q7Z756|ensembl:ENSP00000430897 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:cc71l_human(display_long)|uniprotkb:C7orf74(gene name synonym)|uniprotkb:CCDC71L(gene name)|psi-mi:CCDC71L(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_787080.2|ensembl:ENSG00000253276(gene)|ensembl:ENST00000523505(transcript)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0045600"(positive regulation of fat cell differentiation)|interpro:IPR026695|mint:Q8N9Z2|uniprotkb:Q8N9Z2(identity)|entrezgene/locuslink:168455(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:EZIjQPXDrGzdu/SyF9CrQGxgPuY9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q14186 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|entrezgene/locuslink:7027(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q06587 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q99496 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|entrezgene/locuslink:6045(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q14839 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-372916|uniprotkb:Q8IXZ5|intact:EBI-28978241|ensembl:ENSP00000440542 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:chd4_human(display_long)|uniprotkb:CHD4(gene name)|psi-mi:CHD4(display_short)|uniprotkb:ATP-dependent helicase CHD4(gene name synonym)|uniprotkb:Mi-2 autoantigen 218 kDa protein(gene name synonym)|uniprotkb:Mi2-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) ensembl:ENSP00000440542|ensembl:ENST00000645095|ensembl:ENSP00000496634|refseq:NP_001264.2|refseq:XP_006719021.1|refseq:NP_001284482.1|ensembl:ENSG00000111642(gene)|ensembl:ENST00000544040(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070615"|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q14839|rcsb pdb:1MM2|rcsb pdb:1MM3|rcsb pdb:2EE1|rcsb pdb:2L5U|rcsb pdb:2L75|rcsb pdb:2N5N|rcsb pdb:4O9I|rcsb pdb:6BGG|rcsb pdb:6Q3M|rcsb pdb:6RYR|rcsb pdb:6RYU|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9031628|reactome:R-HSA-9679191|dip:DIP-31183N|uniprotkb:Q14839(identity)|entrezgene/locuslink:1108(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:E9eHT/41SIFRiz54J81hvPQeHIE9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q8IWI9 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-2815196|uniprotkb:E7ENI0|uniprotkb:F5H7K2|uniprotkb:Q9H9N7|uniprotkb:Q9H8R3|uniprotkb:Q9Y4E9|uniprotkb:Q9UG69|intact:EBI-11143500|intact:EBI-10969960|ensembl:ENSP00000219905|uniprotkb:B9EGR5 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:mgap_human(display_long)|uniprotkb:MGA(gene name)|psi-mi:MGA(display_short)|uniprotkb:KIAA0518(gene name synonym)|uniprotkb:MAD5(gene name synonym)|uniprotkb:MAX dimerization protein 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_001074010.2|ensembl:ENSP00000219905|ensembl:ENST00000566586|ensembl:ENSP00000456141|ensembl:ENSG00000174197(gene)|ensembl:ENST00000219905(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR018186|interpro:IPR032060|interpro:IPR036638|interpro:IPR036960|interpro:IPR037935|mint:Q8IWI9|reactome:R-HSA-8953750|refseq:NP_001157745.1|dip:DIP-57615N|uniprotkb:Q8IWI9(identity)|entrezgene/locuslink:23269(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:P4lo9EteCvikQQk5kyVkcobitLU9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:O60281 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-1224010|uniprotkb:Q9H8G3|uniprotkb:Q9H8J4|uniprotkb:Q5W0B2|uniprotkb:Q7Z3L7|intact:EBI-28971048|ensembl:ENSP00000358590 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:zn292_human(display_long)|uniprotkb:ZNF292(gene name)|psi-mi:ZNF292(display_short)|uniprotkb:KIAA0530(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) ensembl:ENSP00000358590|refseq:NP_055836.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|ensembl:ENSG00000188994(gene)|interpro:IPR036236|mint:O60281|rcsb pdb:1X3C|ensembl:ENST00000369577(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|uniprotkb:O60281(identity)|entrezgene/locuslink:23036(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:4Ss6SyxGv1bSjSBhSjquUKutB349606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:O60684 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-359923|uniprotkb:Q5VVU3|uniprotkb:B2RDC7|ensembl:ENSP00000362728|uniprotkb:D3DPP5 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:ima7_human(display_long)|uniprotkb:KPNA6(gene name)|psi-mi:KPNA6(display_short)|uniprotkb:IPOA7(gene name synonym)|uniprotkb:Karyopherin subunit alpha-6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_036448.1|ensembl:ENSG00000025800(gene)|ensembl:ENST00000373625(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0019079"(viral genome replication)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0043657"(host cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O60684|rcsb pdb:4UAD|dip:DIP-27609N|uniprotkb:O60684(identity)|entrezgene/locuslink:23633(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:3NsSIcE6BHIqYlvfGRolUKD/5uc9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q5VZL5 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-2514659|intact:EBI-28984130|ensembl:ENSP00000322915|uniprotkb:A0JP19|uniprotkb:O43308|uniprotkb:A0JP20|uniprotkb:Q5T5E2|uniprotkb:Q7L3Q4|uniprotkb:Q5T5E1|intact:EBI-2556245 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:zmym4_human(display_long)|uniprotkb:ZMYM4(gene name)|psi-mi:ZMYM4(display_short)|uniprotkb:KIAA0425(gene name synonym)|uniprotkb:ZNF262(gene name synonym)|uniprotkb:Zinc finger protein 262(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) ensembl:ENSG00000146463(gene)|ensembl:ENST00000314607(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022604"(regulation of cell morphogenesis)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR021893|refseq:XP_016858292.1|refseq:XP_016858293.1|refseq:XP_011540725.1|refseq:XP_011540727.1|refseq:NP_005086.2|ensembl:ENSP00000322915|refseq:XP_005271388.1|uniprotkb:Q5VZL5(identity)|entrezgene/locuslink:9202(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:jc8YwR+37J3uD08cXiUnOA2hHEI9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q6IQ32 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-2838654|uniprotkb:A8K951|uniprotkb:Q9H9P3|uniprotkb:O94943|ensembl:ENSP00000262198 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:adnp2_human(display_long)|uniprotkb:ADNP2(gene name)|psi-mi:ADNP2(display_short)|uniprotkb:KIAA0863(gene name synonym)|uniprotkb:ZNF508(gene name synonym)|uniprotkb:Zinc finger protein 508(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_055728.1|refseq:XP_005266713.1|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0046872"(metal ion binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071300"(cellular response to retinoic acid)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR038861|mint:Q6IQ32|ensembl:ENSG00000101544(gene)|ensembl:ENST00000262198(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|uniprotkb:Q6IQ32(identity)|entrezgene/locuslink:22850(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:yzYCNBnFFszXO4X7vp01+DcaGvs9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q8N9R8 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-4395514|uniprotkb:Q3SXZ1|uniprotkb:Q3SXZ2|uniprotkb:Q5T163|uniprotkb:Q8N1I4|ensembl:ENSP00000336756 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:scai_human(display_long)|uniprotkb:SCAI(gene name)|psi-mi:SCAI(display_short)|uniprotkb:C9orf126(gene name synonym)|uniprotkb:Suppressor of cancer cell invasion protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_001138349.1|refseq:NP_775961.2|ensembl:ENSG00000173611(gene)|ensembl:ENST00000336505(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|interpro:IPR016607(Uncharacterised conserved protein UCP013022)|interpro:IPR022709|mint:Q8N9R8|reactome:R-HSA-5663220|uniprotkb:Q8N9R8(identity)|entrezgene/locuslink:286205(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:7rGLwUVUMTIQHugyN2BTnQwluiY9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:O95785 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-1387294|uniprotkb:B7ZM82|uniprotkb:Q4G0E0|uniprotkb:Q6P6B0|uniprotkb:Q6ZN24|uniprotkb:Q7LDY6|uniprotkb:Q7LDZ1|uniprotkb:Q96IG5|uniprotkb:Q96SQ6|uniprotkb:Q9BUR8|uniprotkb:Q9NPT1|intact:EBI-10967552|uniprotkb:B3KVH1|uniprotkb:M0QY21 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:wiz_human(display_long)|uniprotkb:WIZ(gene name)|psi-mi:WIZ(display_short)|uniprotkb:ZNF803(gene name synonym)|uniprotkb:Widely-interspaced zinc finger-containing protein(gene name synonym)|uniprotkb:Zinc finger protein 803(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_067064.2|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001317324.1|interpro:IPR036236|mint:O95785|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|go:"GO:0030496"(midbody)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990226"(histone methyltransferase binding)|uniprotkb:O95785(identity)|entrezgene/locuslink:58525(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:FMQwuMDlEC/Zdsnayyl7kpQSmyg9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q8ND82 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-8831272|uniprotkb:Q9NXR3|uniprotkb:A8K2V8|ensembl:ENSP00000360017 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:z280c_human(display_long)|uniprotkb:SUHW3(gene name synonym)|uniprotkb:Suppressor of hairy wing homolog 3(gene name synonym)|uniprotkb:ZNF633(gene name synonym)|uniprotkb:Zinc finger protein 633(gene name synonym)|uniprotkb:ZNF280C(gene name)|psi-mi:ZNF280C(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_060136.1|ensembl:ENSG00000056277(gene)|ensembl:ENST00000370978(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR025243|interpro:IPR036236|mint:Q8ND82|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|uniprotkb:Q8ND82(identity)|entrezgene/locuslink:55609(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:cwFw98IKrHrRV8pySnNy4Tl0g0k9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q13111 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-1020839|uniprotkb:Q7Z7K3|uniprotkb:Q9UJY8|uniprotkb:Q6NXG5|intact:EBI-28985893|ensembl:ENSP00000301280 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:caf1a_human(display_long)|uniprotkb:CHAF1A(gene name)|psi-mi:CHAF1A(display_short)|uniprotkb:CAF(gene name synonym)|uniprotkb:CAF1P150(gene name synonym)|uniprotkb:Chromatin assembly factor I p150 subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_005474.2|ensembl:ENSG00000167670(gene)|ensembl:ENST00000301280(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070087"(chromo shadow domain binding)|interpro:IPR022043|interpro:IPR029091|interpro:IPR029105|mint:Q13111|ensembl:ENSP00000301280|dip:DIP-31135N|uniprotkb:Q13111(identity)|entrezgene/locuslink:10036(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:8ZlQPVvmtN638aK8ZblErN5Bhjo9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:P84243 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-120658|uniprotkb:P06351|uniprotkb:P33155|uniprotkb:Q5VV55|uniprotkb:Q5VV56|uniprotkb:Q66I33|uniprotkb:Q9V3W4|ensembl:ENSP00000254810|ensembl:ENSP00000355778|ensembl:ENSP00000355780|ensembl:ENSP00000355781|ensembl:ENSP00000465813|ensembl:ENSP00000466020|ensembl:ENSP00000468714|ensembl:ENSP00000499275|ensembl:ENSP00000499385|ensembl:ENSP00000499800 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:h33_human(display_long)|uniprotkb:H3-3A(gene name)|psi-mi:H3-3A(display_short)|uniprotkb:H3-3B(gene name)|psi-mi:H3-3B(display_short)|uniprotkb:H3.3A(gene name synonym)|uniprotkb:H3.3B(gene name synonym)|uniprotkb:H3F3(gene name synonym)|uniprotkb:H3F3A(gene name synonym)|uniprotkb:H3F3B(gene name synonym)|uniprotkb:PP781(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_002098.1|refseq:NP_005315.1|rcsb pdb:4H9N|rcsb pdb:3QL9|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:3QLA|rcsb pdb:3QLC|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4L58|rcsb pdb:4N4I|rcsb pdb:3WTP|rcsb pdb:4O62|rcsb pdb:4QQ4|rcsb pdb:4TMP|rcsb pdb:4GNE|rcsb pdb:4GNF|rcsb pdb:4U7T|rcsb pdb:4GNG|rcsb pdb:4W5A|rcsb pdb:4GU0|rcsb pdb:4GUR|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:4GUS|rcsb pdb:4GY5|rcsb pdb:5DWQ|rcsb pdb:5DX0|rcsb pdb:5JA4|rcsb pdb:5JJY|ensembl:ENSG00000132475(gene)|ensembl:ENSG00000163041(gene)|rcsb pdb:5JLB|rcsb pdb:5KDM|rcsb pdb:5X7X|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6HGT|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6J9J|rcsb pdb:6PZV|rcsb pdb:6QXZ|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6U04|rcsb pdb:7A08|reactome:R-HSA-427413|rcsb pdb:7CIZ|reactome:R-HSA-5250924|reactome:R-HSA-5334118|rcsb pdb:7CJ0|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-983231|rcsb pdb:7CWH|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-427359|reactome:R-HSA-427389|ensembl:ENST00000254810(transcript)|ensembl:ENST00000366813(transcript)|ensembl:ENST00000366815(transcript)|ensembl:ENST00000366816(transcript)|ensembl:ENST00000586607(transcript)|ensembl:ENST00000587560(transcript)|ensembl:ENST00000589599(transcript)|ensembl:ENST00000655399(transcript)|ensembl:ENST00000661429(transcript)|ensembl:ENST00000666609(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P84243|rcsb pdb:2L43|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3AV2|rcsb pdb:3JVK|rcsb pdb:3MUK|rcsb pdb:3MUL|dip:DIP-40046N|uniprotkb:P84243(identity)|entrezgene/locuslink:3021(identity)|entrezgene/locuslink:3020(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:cRqA5/IBNfIbbxAnbwLqzXip20I9606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q14257 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-356710|uniprotkb:A8MTG6|uniprotkb:Q53XN8|ensembl:ENSP00000378349|uniprotkb:F8WCY5 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:rcn2_human(display_long)|uniprotkb:RCN2(gene name)|psi-mi:RCN2(display_short)|uniprotkb:ERC55(gene name synonym)|uniprotkb:Calcium-binding protein ERC-55(gene name synonym)|uniprotkb:E6-binding protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831531|imex:IM-21659-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity)|ddbj/embl/genbank:BC000954(identity) refseq:NP_002893.1|ensembl:ENST00000394885(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|ensembl:ENSG00000117906(gene)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q14257|refseq:NP_001258766.1|uniprotkb:Q14257(identity)|entrezgene/locuslink:5955(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:99ru/7eYUvZ5xdb+x4inbib3PP89606 intact-crc:B69E6CD3FC8673D4|rigid:kgSSKJTw7hep0oIHi2svvkER/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14781 uniprotkb:Q7Z417 intact:EBI-745934|uniprotkb:Q9BTB1|uniprotkb:Q0VDA5|ensembl:ENSP00000308750 intact:EBI-1210753|intact:EBI-10172018|uniprotkb:A1L3A7|uniprotkb:Q9P2M5|uniprotkb:A1L3A6|ensembl:ENSP00000225388 psi-mi:cbx2_human(display_long)|uniprotkb:CBX2(gene name)|psi-mi:CBX2(display_short) psi-mi:nufp2_human(display_long)|uniprotkb:NUFIP2(gene name)|psi-mi:NUFIP2(display_short)|uniprotkb:KIAA1321(gene name synonym)|uniprotkb:PIG1(orf name)|uniprotkb:FMRP-interacting protein 2(gene name synonym)|uniprotkb:82 kDa FMRP-interacting protein(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 1 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831509|imex:IM-21659-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005180.1|refseq:NP_116036.1|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|go:"GO:0045137"(development of primary sexual characteristics)|interpro:IPR042796|mint:Q14781|rcsb pdb:2D9U|rcsb pdb:3H91|rcsb pdb:5EPK|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSG00000173894(gene)|ensembl:ENST00000310942(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|dip:DIP-48604N|uniprotkb:Q14781(identity)|ddbj/embl/genbank:BC004252(identity)|entrezgene/locuslink:84733(identity) refseq:NP_065823.1|dip:DIP-29023N|ensembl:ENSG00000108256(gene)|ensembl:ENST00000225388(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR032747|mint:Q7Z417|uniprotkb:Q7Z417(identity)|entrezgene/locuslink:57532(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:220eC8UGlmAHHP2WAhZdAveHC3s9606 rogid:zdbkRisveP+8g70umfbEPHTnAgk9606 intact-crc:7CBC9A10307EC95C|rigid:oRkVwlvnwI6X+czKI85hVdnuZjI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14781 uniprotkb:P20700 intact:EBI-745934|uniprotkb:Q9BTB1|uniprotkb:Q0VDA5|ensembl:ENSP00000308750 intact:EBI-968218|ensembl:ENSP00000261366|uniprotkb:Q3SYN7|uniprotkb:Q96EI6|uniprotkb:B2R6J6 psi-mi:cbx2_human(display_long)|uniprotkb:CBX2(gene name)|psi-mi:CBX2(display_short) psi-mi:lmnb1_human(display_long)|uniprotkb:LMNB1(gene name)|psi-mi:LMNB1(display_short)|uniprotkb:LMN2(gene name synonym)|uniprotkb:LMNB(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831509|imex:IM-21659-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005180.1|refseq:NP_116036.1|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|go:"GO:0045137"(development of primary sexual characteristics)|interpro:IPR042796|mint:Q14781|rcsb pdb:2D9U|rcsb pdb:3H91|rcsb pdb:5EPK|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSG00000173894(gene)|ensembl:ENST00000310942(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|dip:DIP-48604N|uniprotkb:Q14781(identity)|ddbj/embl/genbank:BC004252(identity)|entrezgene/locuslink:84733(identity) ensembl:ENSG00000113368(gene)|ensembl:ENST00000261366(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043274"(phospholipase binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:P20700|rcsb pdb:2KPW|go:"GO:0005654"(nucleoplasm)|rcsb pdb:3JT0|rcsb pdb:3TYY|rcsb pdb:3UMN|rcsb pdb:5VVX|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|reactome:R-HSA-2559584|reactome:R-HSA-1221632|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-352238|reactome:R-HSA-4419969|reactome:R-HSA-8862803|reactome:R-HSA-8950505|reactome:R-HSA-9013405|reactome:R-HSA-9035034|refseq:NP_005564.1|dip:DIP-34897N|uniprotkb:P20700(identity)|entrezgene/locuslink:4001(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:220eC8UGlmAHHP2WAhZdAveHC3s9606 rogid:ZLv4OS5VSmn3sdXB9IP98YdQ+Iw9606 intact-crc:7CBC9A10307EC95C|rigid:oRkVwlvnwI6X+czKI85hVdnuZjI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14781 uniprotkb:Q9P0W8 intact:EBI-745934|uniprotkb:Q9BTB1|uniprotkb:Q0VDA5|ensembl:ENSP00000308750 intact:EBI-6152737|uniprotkb:Q5BKY5|uniprotkb:Q9P0W7|uniprotkb:Q96HF3|uniprotkb:Q8WX30|uniprotkb:Q9H0X0|ensembl:ENSP00000377176 psi-mi:cbx2_human(display_long)|uniprotkb:CBX2(gene name)|psi-mi:CBX2(display_short) psi-mi:spat7_human(display_long)|uniprotkb:HSD-3.1(gene name synonym)|uniprotkb:HSD3(gene name synonym)|uniprotkb:Spermatogenesis-associated protein HSD3(gene name synonym)|uniprotkb:SPATA7(gene name)|psi-mi:SPATA7(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831509|imex:IM-21659-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005180.1|refseq:NP_116036.1|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|go:"GO:0045137"(development of primary sexual characteristics)|interpro:IPR042796|mint:Q14781|rcsb pdb:2D9U|rcsb pdb:3H91|rcsb pdb:5EPK|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSG00000173894(gene)|ensembl:ENST00000310942(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|dip:DIP-48604N|uniprotkb:Q14781(identity)|ddbj/embl/genbank:BC004252(identity)|entrezgene/locuslink:84733(identity) refseq:NP_001035518.1|refseq:NP_060888.2|ensembl:ENSG00000042317(gene)|ensembl:ENST00000393545(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050896"(response to stimulus)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903546"(protein localization to photoreceptor outer segment)|go:"GO:1903621"(protein localization to photoreceptor connecting cilium)|interpro:IPR029357|mint:Q9P0W8|uniprotkb:Q9P0W8(identity)|entrezgene/locuslink:55812(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:220eC8UGlmAHHP2WAhZdAveHC3s9606 rogid:g+djqWT3cKjfCPnHVufeoKm9dYM9606 intact-crc:7CBC9A10307EC95C|rigid:oRkVwlvnwI6X+czKI85hVdnuZjI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q9H081 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-1001205|uniprotkb:Q96N24|ensembl:ENSP00000370557|ensembl:ENSP00000461252|ensembl:ENSP00000484532 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:mis12_human(display_long)|uniprotkb:MIS12(gene name)|psi-mi:MIS12(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831893|imex:IM-21659-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|ddbj/embl/genbank:BC006821(identity)|entrezgene/locuslink:23468(identity) refseq:NP_001245146.1|refseq:NP_001245147.1|refseq:NP_001245148.1|refseq:NP_001245149.1|refseq:XP_016880522.1|refseq:XP_016880523.1|refseq:XP_016880524.1|refseq:NP_076944.1|ensembl:ENSG00000167842(gene)|ensembl:ENST00000381165(transcript)|ensembl:ENST00000573759(transcript)|ensembl:ENST00000611091(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR008685(Mis12)|mint:Q9H081|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_005256854.1|uniprotkb:Q9H081(identity)|entrezgene/locuslink:79003(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:1qNMwDq3AYOWnRnPa2u3yt7O4109606 intact-crc:AA56AD6E1BD18266|rigid:P0Nx+r2FrfPS43c78E0cs8dOeFY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q7Z3K3 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-1389308|uniprotkb:O75049|uniprotkb:Q5SZS2|uniprotkb:Q5SZS3|uniprotkb:Q5SZS4|uniprotkb:Q8TDZ7|uniprotkb:Q9Y4X7|uniprotkb:Q3LIC4|uniprotkb:Q5SZS1|intact:EBI-2560449|intact:EBI-11742841|uniprotkb:B4DTP8|uniprotkb:B4DYL9|uniprotkb:B7ZBY5|uniprotkb:E9PM80|intact:EBI-14072025|intact:EBI-17205119|intact:EBI-22321456|intact:EBI-12748249|intact:EBI-16429759|ensembl:ENSP00000271715 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:pogz_human(display_long)|uniprotkb:POGZ(gene name)|psi-mi:POGZ(display_short)|uniprotkb:KIAA0461(gene name synonym)|uniprotkb:Nbla00003(orf name)|uniprotkb:SUHW5(gene name synonym)|uniprotkb:ZNF280E(gene name synonym)|uniprotkb:ZNF635(gene name synonym)|uniprotkb:Suppressor of hairy wing homolog 5(gene name synonym)|uniprotkb:Zinc finger protein 280E(gene name synonym)|uniprotkb:Zinc finger protein 635(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831893|imex:IM-21659-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|ddbj/embl/genbank:BC006821(identity)|entrezgene/locuslink:23468(identity) refseq:NP_001181866.1|refseq:NP_001181867.1|refseq:NP_055915.2|refseq:NP_665739.3|refseq:NP_997054.1|refseq:XP_016856234.1|refseq:XP_016856235.1|refseq:XP_016856237.1|refseq:XP_016856238.1|refseq:XP_005245056.1|refseq:XP_005245057.1|refseq:XP_005245058.1|refseq:XP_005245062.1|refseq:XP_005245063.1|dip:DIP-38044N|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSG00000143442(gene)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|ensembl:ENST00000271715(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR004875(CENP-B protein)|interpro:IPR006600(Centromere protein B, helix-turn-helix)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q7Z3K3|rcsb pdb:2E72|rcsb pdb:2N3A|rcsb pdb:6EMP|uniprotkb:Q7Z3K3(identity)|entrezgene/locuslink:23126(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:sCOIY8KsHRQtfcoSA9Tixl9yIsc9606 intact-crc:AA56AD6E1BD18266|rigid:P0Nx+r2FrfPS43c78E0cs8dOeFY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q9H410 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-1001144|uniprotkb:E1P5U9|uniprotkb:Q5JW56|uniprotkb:Q9H8P4|ensembl:ENSP00000362855|ensembl:ENSP00000389810|uniprotkb:Q5JW55|uniprotkb:B4DWT2 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:dsn1_human(display_long)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)|uniprotkb:C20orf172(gene name synonym)|uniprotkb:MIS13(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831893|imex:IM-21659-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|ddbj/embl/genbank:BC006821(identity)|entrezgene/locuslink:23468(identity) refseq:NP_001138789.1|refseq:NP_001138787.1|refseq:NP_001138788.1|refseq:NP_079194.3|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-68877|reactome:R-HSA-9648025|rcsb pdb:5LSK|ensembl:ENSG00000149636(gene)|ensembl:ENST00000373750(transcript)|ensembl:ENST00000426836(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000939"(inner kinetochore)|go:"GO:0001650"(fibrillar center)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0051301"(cell division)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|mint:Q9H410|rcsb pdb:5LSI|rcsb pdb:5LSJ|refseq:NP_001138790.1|refseq:XP_006723939.1|uniprotkb:Q9H410(identity)|entrezgene/locuslink:79980(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:cJ0wCtpLS+YkMj83k/SubkpHwuE9606 intact-crc:AA56AD6E1BD18266|rigid:P0Nx+r2FrfPS43c78E0cs8dOeFY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q9BQF6 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-766251|uniprotkb:Q7Z3F4|uniprotkb:Q96PS5|uniprotkb:Q9C0F6|uniprotkb:Q9HBT5|uniprotkb:A1L3A5|uniprotkb:A8MW39|uniprotkb:B7WNW8|ensembl:ENSP00000377655 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:senp7_human(display_long)|uniprotkb:SUMO-1-specific protease 2(gene name synonym)|uniprotkb:Sentrin/SUMO-specific protease SENP7(gene name synonym)|uniprotkb:SENP7(gene name)|psi-mi:SENP7(display_short)|uniprotkb:KIAA1707(gene name synonym)|uniprotkb:SSP2(gene name synonym)|uniprotkb:SUSP2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831893|imex:IM-21659-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|ddbj/embl/genbank:BC006821(identity)|entrezgene/locuslink:23468(identity) refseq:NP_001070671.1|refseq:NP_001269730.1|refseq:NP_001269731.1|refseq:NP_001269732.1|refseq:NP_001269733.1|refseq:NP_065705.3|refseq:XP_016862414.1|ensembl:ENSG00000138468(gene)|ensembl:ENST00000394095(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016926"(protein desumoylation)|go:"GO:0070139"(SUMO-specific endopeptidase activity)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|rcsb pdb:3EAY|interpro:IPR038765|uniprotkb:Q9BQF6(identity)|entrezgene/locuslink:57337(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:dLL7YHqSkqW17N+IHtiDf0yC07Q9606 intact-crc:AA56AD6E1BD18266|rigid:P0Nx+r2FrfPS43c78E0cs8dOeFY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q96IY1 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-2554690|uniprotkb:Q9H2M5|uniprotkb:Q5SY75|uniprotkb:Q9Y415|uniprotkb:Q9NRN8|ensembl:ENSP00000355944|uniprotkb:E7ETD5 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:nsl1_human(display_long)|uniprotkb:C1orf48(gene name synonym)|uniprotkb:DC8(orf name)|uniprotkb:DC31(orf name)|uniprotkb:MIS14(orf name)|uniprotkb:NSL1(gene name)|psi-mi:NSL1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831893|imex:IM-21659-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|ddbj/embl/genbank:BC006821(identity)|entrezgene/locuslink:23468(identity) refseq:NP_056286.3|ensembl:ENSG00000117697(gene)|ensembl:ENST00000366977(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|go:"GO:0051301"(cell division)|interpro:IPR013950(Kinetochore Mis14)|mint:Q96IY1|rcsb pdb:4NF9|rcsb pdb:5LSI|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-2500257|reactome:R-HSA-9648025|refseq:NP_001036014.1|uniprotkb:Q96IY1(identity)|entrezgene/locuslink:25936(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:w4K2MEHLfZvFECNhtDanXWF0LQk9606 intact-crc:AA56AD6E1BD18266|rigid:P0Nx+r2FrfPS43c78E0cs8dOeFY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q13263 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-78139|uniprotkb:O00677|ensembl:ENSP00000253024|uniprotkb:Q7Z632|uniprotkb:Q93040|uniprotkb:Q96IM1 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:tif1b_human(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831893|imex:IM-21659-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|ddbj/embl/genbank:BC006821(identity)|entrezgene/locuslink:23468(identity) ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6QAJ|rcsb pdb:6QU1|reactome:R-HSA-212436|reactome:R-HSA-3899300|reactome:R-HSA-9609690|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q13263|rcsb pdb:1FP0|rcsb pdb:2RO1|rcsb pdb:2YVR|rcsb pdb:6H3A|rcsb pdb:6I9H|refseq:NP_005753.1|dip:DIP-30891N|uniprotkb:Q13263(identity)|entrezgene/locuslink:10155(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606 intact-crc:AA56AD6E1BD18266|rigid:P0Nx+r2FrfPS43c78E0cs8dOeFY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q6P1K2 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-713832|uniprotkb:Q5TCJ8|uniprotkb:Q5TCJ9|uniprotkb:Q5TCK3|uniprotkb:Q69YZ9|uniprotkb:Q6PHR4|uniprotkb:Q86VJ6|uniprotkb:Q8N4T6|uniprotkb:Q9UBQ3|uniprotkb:A8K0C5|intact:EBI-2554676|uniprotkb:Q5TCK0|ensembl:ENSP00000357260|uniprotkb:Q5TCK1|uniprotkb:Q6ZVE6 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:pmf1_human(display_long)|uniprotkb:PMF1(gene name)|psi-mi:PMF1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831893|imex:IM-21659-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|ddbj/embl/genbank:BC006821(identity)|entrezgene/locuslink:23468(identity) ensembl:ENSG00000160783(gene)|ensembl:ENST00000368277(transcript)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0051301"(cell division)|interpro:IPR007128(Nnf1)|mint:Q6P1K2|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001186582.1|refseq:NP_001186583.1|refseq:NP_001186590.1|refseq:NP_001186592.1|refseq:NP_009152.2|uniprotkb:Q6P1K2(identity)|entrezgene/locuslink:11243(identity)|entrezgene/locuslink:100527963(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:76xPGmFgI3Pt1gsZMb3aD4hpPWM9606 intact-crc:AA56AD6E1BD18266|rigid:P0Nx+r2FrfPS43c78E0cs8dOeFY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q9BWN1 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-748167|uniprotkb:Q8WTX2|intact:EBI-28975604|ensembl:ENSP00000300835|ensembl:ENSP00000441641 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:prr14_human(display_long)|uniprotkb:PRR14(gene name)|psi-mi:PRR14(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831893|imex:IM-21659-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|ddbj/embl/genbank:BC006821(identity)|entrezgene/locuslink:23468(identity) ensembl:ENSP00000300835|ensembl:ENSP00000441641|refseq:NP_076936.1|refseq:NP_001307393.1|ensembl:ENSG00000156858(gene)|ensembl:ENST00000300835(transcript)|ensembl:ENST00000542965(transcript)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0007517"(muscle organ development)|interpro:IPR026320|interpro:IPR028149|uniprotkb:Q9BWN1(identity)|entrezgene/locuslink:78994(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:09dYdbqpgWweItEVD7Q6qHbEo7Q9606 intact-crc:AA56AD6E1BD18266|rigid:P0Nx+r2FrfPS43c78E0cs8dOeFY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q8N9Z2 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-8831284|uniprotkb:Q7Z756|ensembl:ENSP00000430897 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:cc71l_human(display_long)|uniprotkb:C7orf74(gene name synonym)|uniprotkb:CCDC71L(gene name)|psi-mi:CCDC71L(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831893|imex:IM-21659-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|ddbj/embl/genbank:BC006821(identity)|entrezgene/locuslink:23468(identity) refseq:NP_787080.2|ensembl:ENSG00000253276(gene)|ensembl:ENST00000523505(transcript)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0045600"(positive regulation of fat cell differentiation)|interpro:IPR026695|mint:Q8N9Z2|uniprotkb:Q8N9Z2(identity)|entrezgene/locuslink:168455(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:EZIjQPXDrGzdu/SyF9CrQGxgPuY9606 intact-crc:AA56AD6E1BD18266|rigid:P0Nx+r2FrfPS43c78E0cs8dOeFY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q96CS4 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-4395570|uniprotkb:Q658J5|ensembl:ENSP00000287461 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:zn689_human(display_long)|uniprotkb:ZNF689(gene name)|psi-mi:ZNF689(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831893|imex:IM-21659-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|ddbj/embl/genbank:BC006821(identity)|entrezgene/locuslink:23468(identity) refseq:NP_612456.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|ensembl:ENSG00000156853(gene)|ensembl:ENST00000287461(transcript)|uniprotkb:Q96CS4(identity)|entrezgene/locuslink:115509(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:Pu6f7CUHQ9L6Ovrx4lDRoWm5mGA9606 intact-crc:AA56AD6E1BD18266|rigid:P0Nx+r2FrfPS43c78E0cs8dOeFY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q9UI95 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-77889|ensembl:ENSP00000235310|ensembl:ENSP00000365855|ensembl:ENSP00000365882|uniprotkb:Q5TGW7|uniprotkb:Q9UNA7|uniprotkb:Q9Y6I6|uniprotkb:B3KNE3 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:md2l2_human(display_long)|uniprotkb:MAD2L2(gene name)|psi-mi:MAD2L2(display_short)|uniprotkb:MAD2B(gene name synonym)|uniprotkb:REV7(gene name synonym)|uniprotkb:Mitotic arrest deficient 2-like protein 2(gene name synonym)|uniprotkb:REV7 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831893|imex:IM-21659-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|ddbj/embl/genbank:BC006821(identity)|entrezgene/locuslink:23468(identity) ensembl:ENSG00000116670(gene)|ensembl:ENST00000235310(transcript)|ensembl:ENST00000376667(transcript)|ensembl:ENST00000376692(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007015"(actin filament organization)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0016035"(zeta DNA polymerase complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042772"(DNA damage response, signal transduction resulting in transcription)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR036570|rcsb pdb:3ABD|rcsb pdb:3ABE|rcsb pdb:3VU7|rcsb pdb:4EXT|rcsb pdb:4GK0|rcsb pdb:4GK5|rcsb pdb:5XPT|rcsb pdb:5XPU|rcsb pdb:6BC8|rcsb pdb:6BCD|rcsb pdb:6BI7|rcsb pdb:6K07|rcsb pdb:6K08|rcsb pdb:6KEA|rcsb pdb:6KTO|rcsb pdb:6M7A|rcsb pdb:6M7B|rcsb pdb:6NIF|rcsb pdb:6VE5|rcsb pdb:6WS0|rcsb pdb:6WS5|rcsb pdb:6WW9|rcsb pdb:6WWA|rcsb pdb:7L9P|reactome:R-HSA-110312|reactome:R-HSA-5655862|reactome:R-HSA-5656121|refseq:NP_001120797.1|refseq:NP_006332.3|refseq:XP_011538809.1|uniprotkb:Q9UI95(identity)|entrezgene/locuslink:10459(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:KBeawMhcP3iXUel74pUDl85A/vw9606 intact-crc:AA56AD6E1BD18266|rigid:P0Nx+r2FrfPS43c78E0cs8dOeFY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:O75556 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-8830751|ensembl:ENSP00000244930 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:sg2a1_human(display_long)|uniprotkb:LIPHC(gene name synonym)|uniprotkb:Lacryglobin(gene name synonym)|uniprotkb:Lipophilin-C(gene name synonym)|uniprotkb:MGB2(gene name synonym)|uniprotkb:Mammaglobin-2(gene name synonym)|uniprotkb:Secretoglobin family 2A member 1(gene name synonym)|uniprotkb:UGB3(gene name synonym)|uniprotkb:SCGB2A1(gene name)|psi-mi:SCGB2A1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831893|imex:IM-21659-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|ddbj/embl/genbank:BC006821(identity)|entrezgene/locuslink:23468(identity) refseq:NP_002398.1|ensembl:ENSG00000124939(gene)|ensembl:ENST00000244930(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0030521"(androgen receptor signaling pathway)|interpro:IPR016126(Secretoglobin)|interpro:IPR035960|uniprotkb:O75556(identity)|entrezgene/locuslink:4246(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:w+3NKAb7Len68q3aS4Re1qKbOac9606 intact-crc:AA56AD6E1BD18266|rigid:P0Nx+r2FrfPS43c78E0cs8dOeFY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q9C0D4 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-8831278|uniprotkb:Q96LN8|ensembl:ENSP00000317614 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:z518b_human(display_long)|uniprotkb:KIAA1729(gene name synonym)|uniprotkb:ZNF518B(gene name)|psi-mi:ZNF518B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831893|imex:IM-21659-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|ddbj/embl/genbank:BC006821(identity)|entrezgene/locuslink:23468(identity) refseq:XP_016864273.1|refseq:XP_016864274.1|refseq:XP_016864275.1|refseq:NP_444270.2|refseq:XP_005248250.1|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0046872"(metal ion binding)|ensembl:ENSG00000178163(gene)|ensembl:ENST00000326756(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|uniprotkb:Q9C0D4(identity)|entrezgene/locuslink:85460(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:4dw44329P6DHBaeU+tkpIAiWtss9606 intact-crc:AA56AD6E1BD18266|rigid:P0Nx+r2FrfPS43c78E0cs8dOeFY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q09028 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831893|imex:IM-21659-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|ddbj/embl/genbank:BC006821(identity)|entrezgene/locuslink:23468(identity) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|entrezgene/locuslink:5928(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 intact-crc:AA56AD6E1BD18266|rigid:P0Nx+r2FrfPS43c78E0cs8dOeFY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:O60281 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-1224010|uniprotkb:Q9H8G3|uniprotkb:Q9H8J4|uniprotkb:Q5W0B2|uniprotkb:Q7Z3L7|intact:EBI-28971048|ensembl:ENSP00000358590 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:zn292_human(display_long)|uniprotkb:ZNF292(gene name)|psi-mi:ZNF292(display_short)|uniprotkb:KIAA0530(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831893|imex:IM-21659-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|ddbj/embl/genbank:BC006821(identity)|entrezgene/locuslink:23468(identity) ensembl:ENSP00000358590|refseq:NP_055836.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|ensembl:ENSG00000188994(gene)|interpro:IPR036236|mint:O60281|rcsb pdb:1X3C|ensembl:ENST00000369577(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|uniprotkb:O60281(identity)|entrezgene/locuslink:23036(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:4Ss6SyxGv1bSjSBhSjquUKutB349606 intact-crc:AA56AD6E1BD18266|rigid:P0Nx+r2FrfPS43c78E0cs8dOeFY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q14839 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-372916|uniprotkb:Q8IXZ5|intact:EBI-28978241|ensembl:ENSP00000440542 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:chd4_human(display_long)|uniprotkb:CHD4(gene name)|psi-mi:CHD4(display_short)|uniprotkb:ATP-dependent helicase CHD4(gene name synonym)|uniprotkb:Mi-2 autoantigen 218 kDa protein(gene name synonym)|uniprotkb:Mi2-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831893|imex:IM-21659-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|ddbj/embl/genbank:BC006821(identity)|entrezgene/locuslink:23468(identity) ensembl:ENSP00000440542|ensembl:ENST00000645095|ensembl:ENSP00000496634|refseq:NP_001264.2|refseq:XP_006719021.1|refseq:NP_001284482.1|ensembl:ENSG00000111642(gene)|ensembl:ENST00000544040(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070615"|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q14839|rcsb pdb:1MM2|rcsb pdb:1MM3|rcsb pdb:2EE1|rcsb pdb:2L5U|rcsb pdb:2L75|rcsb pdb:2N5N|rcsb pdb:4O9I|rcsb pdb:6BGG|rcsb pdb:6Q3M|rcsb pdb:6RYR|rcsb pdb:6RYU|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9031628|reactome:R-HSA-9679191|dip:DIP-31183N|uniprotkb:Q14839(identity)|entrezgene/locuslink:1108(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:E9eHT/41SIFRiz54J81hvPQeHIE9606 intact-crc:AA56AD6E1BD18266|rigid:P0Nx+r2FrfPS43c78E0cs8dOeFY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q92769 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-301821|uniprotkb:Q5SRI8|uniprotkb:Q5SZ86|uniprotkb:Q8NEH4|uniprotkb:B4DL58|ensembl:ENSP00000430432|uniprotkb:E1P561|uniprotkb:B3KRS5 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:hdac2_human(display_long)|uniprotkb:HDAC2(gene name)|psi-mi:HDAC2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831893|imex:IM-21659-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|ddbj/embl/genbank:BC006821(identity)|entrezgene/locuslink:23468(identity) go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035094"(response to nicotine)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042220"(response to cocaine)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q92769|rcsb pdb:3MAX|rcsb pdb:4LXZ|rcsb pdb:4LY1|rcsb pdb:5IWG|rcsb pdb:5IX0|rcsb pdb:6G3O|rcsb pdb:6WBW|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000196591(gene)|ensembl:ENST00000519065(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|rcsb pdb:6WHN|rcsb pdb:6WHO|rcsb pdb:6WHQ|rcsb pdb:6WHZ|rcsb pdb:6WI3|rcsb pdb:6XDM|rcsb pdb:6XEB|rcsb pdb:6XEC|rcsb pdb:7KBG|rcsb pdb:7KBH|rcsb pdb:7LTG|rcsb pdb:7LTK|rcsb pdb:7LTL|reactome:R-HSA-193670|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9615017|reactome:R-HSA-9619665|reactome:R-HSA-9679191|reactome:R-HSA-983231|rcsb pdb:6WBZ|refseq:NP_001518.3|dip:DIP-24220N|refseq:XP_011534090.1|refseq:XP_016866288.1|uniprotkb:Q92769(identity)|entrezgene/locuslink:3066(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:K4PpGz9E9/TrQZsgvrJuc+uYCn89606 intact-crc:AA56AD6E1BD18266|rigid:P0Nx+r2FrfPS43c78E0cs8dOeFY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q9BYE7 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831893|imex:IM-21659-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|ddbj/embl/genbank:BC006821(identity)|entrezgene/locuslink:23468(identity) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 intact-crc:AA56AD6E1BD18266|rigid:P0Nx+r2FrfPS43c78E0cs8dOeFY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q96JM3 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-2560420|uniprotkb:Q8NC88|uniprotkb:B3KU06|uniprotkb:Q6P181|uniprotkb:Q9BST0|ensembl:ENSP00000354730|ensembl:ENSP00000496699 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:chap1_human(display_long)|uniprotkb:CHAMP(gene name synonym)|uniprotkb:CHAMP1(gene name)|psi-mi:CHAMP1(display_short)|uniprotkb:C13orf8(gene name synonym)|uniprotkb:CAMP(gene name synonym)|uniprotkb:KIAA1802(gene name synonym)|uniprotkb:ZNF828(gene name synonym)|uniprotkb:Zinc finger protein 828(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831893|imex:IM-21659-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|ddbj/embl/genbank:BC006821(identity)|entrezgene/locuslink:23468(identity) refseq:NP_001157616.1|refseq:NP_001157617.1|refseq:NP_115812.1|ensembl:ENSG00000198824(gene)|ensembl:ENST00000361283(transcript)|ensembl:ENST00000643483(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0016604"(nuclear body)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0046872"(metal ion binding)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0090543"(Flemming body)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR039330|mint:Q96JM3|rcsb pdb:6EKJ|rcsb pdb:6EKL|rcsb pdb:5XPT|rcsb pdb:5XPU|uniprotkb:Q96JM3(identity)|entrezgene/locuslink:283489(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:Di1yMiufHKsy384vPjOgdncmQXw9606 intact-crc:AA56AD6E1BD18266|rigid:P0Nx+r2FrfPS43c78E0cs8dOeFY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q5SXM1 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-2813634|uniprotkb:Q8IVQ9|ensembl:ENSP00000344828|ensembl:ENSP00000440403 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:zn678_human(display_long)|uniprotkb:ZNF678(gene name)|psi-mi:ZNF678(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831893|imex:IM-21659-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|ddbj/embl/genbank:BC006821(identity)|entrezgene/locuslink:23468(identity) ensembl:ENSG00000181450(gene)|ensembl:ENST00000343776(transcript)|ensembl:ENST00000397097(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|reactome:R-HSA-212436|uniprotkb:Q5SXM1(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:L2MedsqLDOquQ5zWRY3hOnWMF+k9606 intact-crc:AA56AD6E1BD18266|rigid:P0Nx+r2FrfPS43c78E0cs8dOeFY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q6N043 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-4395404|uniprotkb:A1L495|uniprotkb:B2RMT6|uniprotkb:Q6MZM6|uniprotkb:Q6N085|uniprotkb:Q9H0U5|uniprotkb:Q9HCI8|uniprotkb:Q9NXS0|uniprotkb:Q6P2R6|uniprotkb:Q7Z6J5|intact:EBI-28970145|ensembl:ENSP00000267807 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:z280d_human(display_long)|uniprotkb:ZNF280D(gene name)|psi-mi:ZNF280D(display_short)|uniprotkb:KIAA1584(gene name synonym)|uniprotkb:SUHW4(gene name synonym)|uniprotkb:ZNF634(gene name synonym)|uniprotkb:Suppressor of hairy wing homolog 4(gene name synonym)|uniprotkb:Zinc finger protein 634(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831893|imex:IM-21659-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|ddbj/embl/genbank:BC006821(identity)|entrezgene/locuslink:23468(identity) ensembl:ENSP00000267807|ensembl:ENST00000558067|ensembl:ENSP00000454173|ensembl:ENST00000558320|ensembl:ENSP00000453706|ensembl:ENST00000559237|ensembl:ENSP00000454111|ensembl:ENST00000560002|ensembl:ENSP00000453636|refseq:XP_011520004.1|refseq:NP_001002843.1|refseq:NP_060131.2|refseq:NP_001275517.1|refseq:NP_001002844.1|refseq:NP_001275518.1|refseq:XP_016877833.1|refseq:XP_016877834.1|ensembl:ENSG00000137871(gene)|ensembl:ENST00000267807(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR025243|interpro:IPR036236|mint:Q6N043|uniprotkb:Q6N043(identity)|entrezgene/locuslink:54816(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:BYkVW7yPK+LxorbA2quTgne0Txs9606 intact-crc:AA56AD6E1BD18266|rigid:P0Nx+r2FrfPS43c78E0cs8dOeFY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:P83916 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831893|imex:IM-21659-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|ddbj/embl/genbank:BC006821(identity)|entrezgene/locuslink:23468(identity) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|entrezgene/locuslink:10951(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 intact-crc:AA56AD6E1BD18266|rigid:P0Nx+r2FrfPS43c78E0cs8dOeFY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q14257 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-356710|uniprotkb:A8MTG6|uniprotkb:Q53XN8|ensembl:ENSP00000378349|uniprotkb:F8WCY5 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:rcn2_human(display_long)|uniprotkb:RCN2(gene name)|psi-mi:RCN2(display_short)|uniprotkb:ERC55(gene name synonym)|uniprotkb:Calcium-binding protein ERC-55(gene name synonym)|uniprotkb:E6-binding protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831893|imex:IM-21659-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|ddbj/embl/genbank:BC006821(identity)|entrezgene/locuslink:23468(identity) refseq:NP_002893.1|ensembl:ENST00000394885(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|ensembl:ENSG00000117906(gene)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q14257|refseq:NP_001258766.1|uniprotkb:Q14257(identity)|entrezgene/locuslink:5955(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:99ru/7eYUvZ5xdb+x4inbib3PP89606 intact-crc:AA56AD6E1BD18266|rigid:P0Nx+r2FrfPS43c78E0cs8dOeFY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q13112 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-1052944|uniprotkb:Q99548|ensembl:ENSP00000315700 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:caf1b_human(display_long)|uniprotkb:Chromatin assembly factor I p60 subunit(gene name synonym)|uniprotkb:M-phase phosphoprotein 7(gene name synonym)|uniprotkb:CHAF1B(gene name)|psi-mi:CHAF1B(display_short)|uniprotkb:CAF1A(gene name synonym)|uniprotkb:CAF1P60(gene name synonym)|uniprotkb:MPHOSPH7(gene name synonym)|uniprotkb:MPP7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831893|imex:IM-21659-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|ddbj/embl/genbank:BC006821(identity)|entrezgene/locuslink:23468(identity) refseq:NP_005432.1|dip:DIP-29243N|ensembl:ENSG00000159259(gene)|ensembl:ENST00000314103(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR029129|interpro:IPR036322|mint:Q13112|refseq:XP_016883966.1|refseq:XP_016883967.1|uniprotkb:Q13112(identity)|entrezgene/locuslink:8208(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:VVbW9mpUGYMRPxvlEk9FERHIsJs9606 intact-crc:AA56AD6E1BD18266|rigid:P0Nx+r2FrfPS43c78E0cs8dOeFY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q13185 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831893|imex:IM-21659-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|ddbj/embl/genbank:BC006821(identity)|entrezgene/locuslink:23468(identity) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 intact-crc:AA56AD6E1BD18266|rigid:P0Nx+r2FrfPS43c78E0cs8dOeFY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q13111 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-1020839|uniprotkb:Q7Z7K3|uniprotkb:Q9UJY8|uniprotkb:Q6NXG5|intact:EBI-28985893|ensembl:ENSP00000301280 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:caf1a_human(display_long)|uniprotkb:CHAF1A(gene name)|psi-mi:CHAF1A(display_short)|uniprotkb:CAF(gene name synonym)|uniprotkb:CAF1P150(gene name synonym)|uniprotkb:Chromatin assembly factor I p150 subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831893|imex:IM-21659-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|ddbj/embl/genbank:BC006821(identity)|entrezgene/locuslink:23468(identity) refseq:NP_005474.2|ensembl:ENSG00000167670(gene)|ensembl:ENST00000301280(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070087"(chromo shadow domain binding)|interpro:IPR022043|interpro:IPR029091|interpro:IPR029105|mint:Q13111|ensembl:ENSP00000301280|dip:DIP-31135N|uniprotkb:Q13111(identity)|entrezgene/locuslink:10036(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:8ZlQPVvmtN638aK8ZblErN5Bhjo9606 intact-crc:AA56AD6E1BD18266|rigid:P0Nx+r2FrfPS43c78E0cs8dOeFY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:P78371 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831893|imex:IM-21659-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|ddbj/embl/genbank:BC006821(identity)|entrezgene/locuslink:23468(identity) refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695|uniprotkb:P78371(identity)|entrezgene/locuslink:10576(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606 intact-crc:AA56AD6E1BD18266|rigid:P0Nx+r2FrfPS43c78E0cs8dOeFY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q96JM2 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-1210359|uniprotkb:Q8N408|uniprotkb:Q5T0T4|intact:EBI-28975500|ensembl:ENSP00000277225 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:zn462_human(display_long)|uniprotkb:ZNF462(gene name)|psi-mi:ZNF462(display_short)|uniprotkb:KIAA1803(gene name synonym)|uniprotkb:Zinc finger PBX1-interacting protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831893|imex:IM-21659-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|ddbj/embl/genbank:BC006821(identity)|entrezgene/locuslink:23468(identity) refseq:NP_067047.4|ensembl:ENSP00000277225|ensembl:ENST00000441147|ensembl:ENSP00000397306|refseq:XP_006717278.1|refseq:XP_006717279.1|dip:DIP-39340N|ensembl:ENSG00000148143(gene)|ensembl:ENST00000277225(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q96JM2|rcsb pdb:1X6F|uniprotkb:Q96JM2(identity)|entrezgene/locuslink:58499(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:ftIOu4wVkBWJw+4aHw+R+nN44Vc9606 intact-crc:AA56AD6E1BD18266|rigid:P0Nx+r2FrfPS43c78E0cs8dOeFY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q5T3J3 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-473196|ensembl:ENSP00000358778|uniprotkb:Q86XS4|uniprotkb:Q8N3B6|uniprotkb:Q96HT4|uniprotkb:Q9NUM5|uniprotkb:Q9NV32 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:lrif1_human(display_long)|uniprotkb:Receptor-interacting factor 1(gene name synonym)|uniprotkb:LRIF1(gene name)|psi-mi:LRIF1(display_short)|uniprotkb:C1orf103(gene name synonym)|uniprotkb:RIF1(gene name synonym)|uniprotkb:HP1-binding protein enriched in inactive X chromosome protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831893|imex:IM-21659-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|ddbj/embl/genbank:BC006821(identity)|entrezgene/locuslink:23468(identity) ensembl:ENSG00000121931(gene)|ensembl:ENST00000369763(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042974"(retinoic acid receptor binding)|interpro:IPR026191|mint:Q5T3J3|refseq:NP_001006946.1|refseq:NP_060842.3|uniprotkb:Q5T3J3(identity)|entrezgene/locuslink:55791(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:0TZ2ePF1WLfBY9TO/jYZR4GiOKw9606 intact-crc:AA56AD6E1BD18266|rigid:P0Nx+r2FrfPS43c78E0cs8dOeFY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q5TGY3 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-948813|ensembl:ENSP00000247087|ensembl:ENSP00000363123|ensembl:ENSP00000494394|ensembl:ENSP00000495072|ensembl:ENSP00000495665|ensembl:ENSP00000501218|uniprotkb:Q5TGY4|uniprotkb:Q6PJK1|uniprotkb:Q6ZUQ6|uniprotkb:Q99769|uniprotkb:Q9NUF5 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:ahdc1_human(display_long)|uniprotkb:AHDC1(gene name)|psi-mi:AHDC1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831893|imex:IM-21659-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|ddbj/embl/genbank:BC006821(identity)|entrezgene/locuslink:23468(identity) ensembl:ENSG00000126705(gene)|ensembl:ENST00000247087(transcript)|ensembl:ENST00000374011(transcript)|ensembl:ENST00000642245(transcript)|ensembl:ENST00000642416(transcript)|ensembl:ENST00000644989(transcript)|ensembl:ENST00000673934(transcript)|go:"GO:0003677"(DNA binding)|interpro:IPR032757|interpro:IPR039225|mint:Q5TGY3|refseq:NP_001025053.1|refseq:XP_011539557.1|refseq:XP_011539558.1|refseq:XP_011539559.1|refseq:XP_005245905.1|refseq:XP_005245906.1|refseq:XP_005245907.1|refseq:XP_005245908.1|refseq:XP_005245909.1|uniprotkb:Q5TGY3(identity)|entrezgene/locuslink:27245(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:lYUJEAEhxO204mZnqOd4Vf6K/g89606 intact-crc:AA56AD6E1BD18266|rigid:P0Nx+r2FrfPS43c78E0cs8dOeFY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q99832 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831893|imex:IM-21659-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|ddbj/embl/genbank:BC006821(identity)|entrezgene/locuslink:23468(identity) dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|uniprotkb:Q99832(identity)|entrezgene/locuslink:10574(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606 intact-crc:AA56AD6E1BD18266|rigid:P0Nx+r2FrfPS43c78E0cs8dOeFY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q8IWI9 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-2815196|uniprotkb:E7ENI0|uniprotkb:F5H7K2|uniprotkb:Q9H9N7|uniprotkb:Q9H8R3|uniprotkb:Q9Y4E9|uniprotkb:Q9UG69|intact:EBI-11143500|intact:EBI-10969960|ensembl:ENSP00000219905|uniprotkb:B9EGR5 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:mgap_human(display_long)|uniprotkb:MGA(gene name)|psi-mi:MGA(display_short)|uniprotkb:KIAA0518(gene name synonym)|uniprotkb:MAD5(gene name synonym)|uniprotkb:MAX dimerization protein 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831893|imex:IM-21659-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|ddbj/embl/genbank:BC006821(identity)|entrezgene/locuslink:23468(identity) refseq:NP_001074010.2|ensembl:ENSP00000219905|ensembl:ENST00000566586|ensembl:ENSP00000456141|ensembl:ENSG00000174197(gene)|ensembl:ENST00000219905(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR018186|interpro:IPR032060|interpro:IPR036638|interpro:IPR036960|interpro:IPR037935|mint:Q8IWI9|reactome:R-HSA-8953750|refseq:NP_001157745.1|dip:DIP-57615N|uniprotkb:Q8IWI9(identity)|entrezgene/locuslink:23269(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:P4lo9EteCvikQQk5kyVkcobitLU9606 intact-crc:AA56AD6E1BD18266|rigid:P0Nx+r2FrfPS43c78E0cs8dOeFY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q9H2P0 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-1764854|uniprotkb:E1P5Y2|uniprotkb:O94881|uniprotkb:Q5BKU2|uniprotkb:Q9UG34|intact:EBI-28975656|ensembl:ENSP00000342905|ensembl:ENSP00000360662|ensembl:ENSP00000379346|ensembl:ENSP00000379349|ensembl:ENSP00000483881 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:adnp_human(display_long)|uniprotkb:ADNP(gene name)|psi-mi:ADNP(display_short)|uniprotkb:ADNP1(gene name synonym)|uniprotkb:KIAA0784(gene name synonym)|uniprotkb:Activity-dependent neuroprotective protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831893|imex:IM-21659-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|ddbj/embl/genbank:BC006821(identity)|entrezgene/locuslink:23468(identity) refseq:NP_001269460.1|refseq:NP_001269461.1|refseq:XP_011527049.1|refseq:NP_056154.1|refseq:NP_852107.1|ensembl:ENSP00000342905|ensembl:ENSP00000360662|ensembl:ENSP00000379346|ensembl:ENSP00000379349|ensembl:ENSP00000483881|ensembl:ENSG00000101126(gene)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0033484"(nitric oxide homeostasis)|ensembl:ENST00000349014(transcript)|ensembl:ENST00000371602(transcript)|ensembl:ENST00000396029(transcript)|ensembl:ENST00000396032(transcript)|ensembl:ENST00000621696(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007614"(short-term memory)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019934"(cGMP-mediated signaling)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042277"(peptide binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044849"(estrous cycle)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR038861|mint:Q9H2P0|refseq:XP_016883247.1|refseq:XP_016883248.1|refseq:NP_001334440.1|dip:DIP-47288N|uniprotkb:Q9H2P0(identity)|entrezgene/locuslink:23394(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:QJTl6p2b0Lp7HnHP8sFd5Hv+WGk9606 intact-crc:AA56AD6E1BD18266|rigid:P0Nx+r2FrfPS43c78E0cs8dOeFY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q8N9R8 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-4395514|uniprotkb:Q3SXZ1|uniprotkb:Q3SXZ2|uniprotkb:Q5T163|uniprotkb:Q8N1I4|ensembl:ENSP00000336756 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:scai_human(display_long)|uniprotkb:SCAI(gene name)|psi-mi:SCAI(display_short)|uniprotkb:C9orf126(gene name synonym)|uniprotkb:Suppressor of cancer cell invasion protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831893|imex:IM-21659-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|ddbj/embl/genbank:BC006821(identity)|entrezgene/locuslink:23468(identity) refseq:NP_001138349.1|refseq:NP_775961.2|ensembl:ENSG00000173611(gene)|ensembl:ENST00000336505(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|interpro:IPR016607(Uncharacterised conserved protein UCP013022)|interpro:IPR022709|mint:Q8N9R8|reactome:R-HSA-5663220|uniprotkb:Q8N9R8(identity)|entrezgene/locuslink:286205(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:7rGLwUVUMTIQHugyN2BTnQwluiY9606 intact-crc:AA56AD6E1BD18266|rigid:P0Nx+r2FrfPS43c78E0cs8dOeFY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q13129 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-958266|uniprotkb:Q14CQ1|uniprotkb:Q9NU60|ensembl:ENSP00000361857 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:rlf_human(display_long)|uniprotkb:RLF(gene name)|psi-mi:RLF(display_short)|uniprotkb:Rearranged L-myc fusion gene protein(gene name synonym)|uniprotkb:Zn-15-related protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831893|imex:IM-21659-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|ddbj/embl/genbank:BC006821(identity)|entrezgene/locuslink:23468(identity) refseq:NP_036553.2|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|ensembl:ENSG00000117000(gene)|ensembl:ENST00000372771(transcript)|uniprotkb:Q13129(identity)|entrezgene/locuslink:6018(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:nWnF2P2Bh0uPJSAL6a5//1MxOl09606 intact-crc:AA56AD6E1BD18266|rigid:P0Nx+r2FrfPS43c78E0cs8dOeFY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00257 uniprotkb:Q8NHM5 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 intact:EBI-3955564|uniprotkb:Q1RLM7|uniprotkb:Q8NCI2|uniprotkb:Q96HC7|uniprotkb:Q96SL0|uniprotkb:Q96T03|uniprotkb:Q9NS96|uniprotkb:Q9UF75|ensembl:ENSP00000366271|uniprotkb:A8MRS1 psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:kdm2b_human(display_long)|uniprotkb:KDM2B(gene name)|psi-mi:KDM2B(display_short)|uniprotkb:CXXC2(gene name synonym)|uniprotkb:FBL10(gene name synonym)|uniprotkb:FBXL10(gene name synonym)|uniprotkb:JHDM1B(gene name synonym)|uniprotkb:PCCX2(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 2(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 10(gene name synonym)|uniprotkb:F-box protein FBL10(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 10(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1B(gene name synonym)|uniprotkb:Jumonji domain-containing EMSY-interactor methyltransferase motif protein(gene name synonym)|uniprotkb:Protein-containing CXXC domain 2(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1B(gene name synonym)|uniprotkb:NDY1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831786|imex:IM-21659-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|uniprotkb:O00257(identity)|ddbj/embl/genbank:BC014967(identity)|entrezgene/locuslink:8535(identity) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENST00000377071(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0021555"(midbrain-hindbrain boundary morphogenesis)|go:"GO:0021592"(fourth ventricle development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021678"(third ventricle development)|go:"GO:0021993"(initiation of neural tube closure)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|interpro:IPR041070|interpro:IPR041667|mint:Q8NHM5|rcsb pdb:4O64|rcsb pdb:5JH5|rcsb pdb:6BVA|reactome:R-HSA-3214842|refseq:NP_115979.3|ensembl:ENSG00000089094(gene)|refseq:NP_001005366.1|uniprotkb:Q8NHM5(identity)|entrezgene/locuslink:84678(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 rogid:tnMbfP2oxwaaDyHHAigNt5hx4hM9606 intact-crc:83BDF27C773B0D66|rigid:scMtP2CsXOhJNWLJ1RJ5Zhezv2Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00257 uniprotkb:P35227 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 intact:EBI-2129767|uniprotkb:A6NGD8|ensembl:ENSP00000478517|ensembl:ENSP00000478970|ensembl:ENSP00000482063|ensembl:ENSP00000482815|ensembl:ENSP00000488868|ensembl:ENSP00000488872 psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:pcgf2_human(display_long)|uniprotkb:PCGF2(gene name)|psi-mi:PCGF2(display_short)|uniprotkb:MEL18(gene name synonym)|uniprotkb:RNF110(gene name synonym)|uniprotkb:ZNF144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831786|imex:IM-21659-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|uniprotkb:O00257(identity)|ddbj/embl/genbank:BC014967(identity)|entrezgene/locuslink:8535(identity) refseq:NP_009075.1|refseq:XP_016880505.1|refseq:XP_005257697.1|refseq:XP_005257698.1|refseq:XP_005257699.1|dip:DIP-41880N|ensembl:ENSG00000277258(gene)|ensembl:ENSG00000278644(gene)|ensembl:ENST00000610440(transcript)|ensembl:ENST00000611883(transcript)|ensembl:ENST00000616199(transcript)|ensembl:ENST00000620225(transcript)|ensembl:ENST00000631566(transcript)|ensembl:ENST00000631610(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35227|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-5617472|reactome:R-HSA-8953750|uniprotkb:P35227(identity)|entrezgene/locuslink:7703(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 rogid:zppw56VrEl6gEFwtJMCN5cQkPxI9606 intact-crc:83BDF27C773B0D66|rigid:scMtP2CsXOhJNWLJ1RJ5Zhezv2Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00257 uniprotkb:Q99496 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831786|imex:IM-21659-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|uniprotkb:O00257(identity)|ddbj/embl/genbank:BC014967(identity)|entrezgene/locuslink:8535(identity) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|entrezgene/locuslink:6045(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 intact-crc:83BDF27C773B0D66|rigid:scMtP2CsXOhJNWLJ1RJ5Zhezv2Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00257 uniprotkb:Q6W2J9 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831786|imex:IM-21659-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|uniprotkb:O00257(identity)|ddbj/embl/genbank:BC014967(identity)|entrezgene/locuslink:8535(identity) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N|uniprotkb:Q6W2J9(identity)|entrezgene/locuslink:54880(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 intact-crc:83BDF27C773B0D66|rigid:scMtP2CsXOhJNWLJ1RJ5Zhezv2Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00257 uniprotkb:P61981 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 intact:EBI-359832|uniprotkb:O70457|uniprotkb:P35214|uniprotkb:Q6FH52|uniprotkb:Q9UDP2|uniprotkb:Q9UN99|ensembl:ENSP00000306330 psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:1433g_human(display_long)|uniprotkb:YWHAG(gene name)|psi-mi:YWHAG(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831786|imex:IM-21659-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|uniprotkb:O00257(identity)|ddbj/embl/genbank:BC014967(identity)|entrezgene/locuslink:8535(identity) refseq:NP_036611.2|ensembl:ENSG00000170027(gene)|ensembl:ENST00000307630(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006605"(protein targeting)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P61981|rcsb pdb:2B05|rcsb pdb:3UZD|rcsb pdb:4E2E|rcsb pdb:4J6S|rcsb pdb:4O46|rcsb pdb:5D3E|rcsb pdb:6A5S|rcsb pdb:6BYJ|rcsb pdb:6BYL|rcsb pdb:6BZD|rcsb pdb:6FEL|rcsb pdb:6GKF|rcsb pdb:6GKG|rcsb pdb:6S9K|rcsb pdb:6SAD|rcsb pdb:6Y4K|rcsb pdb:6Y6B|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-9614399|dip:DIP-33406N|uniprotkb:P61981(identity)|entrezgene/locuslink:7532(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 rogid:u1cd71h0RPgTOEMrQVhOelsxWnM9606 intact-crc:83BDF27C773B0D66|rigid:scMtP2CsXOhJNWLJ1RJ5Zhezv2Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00257 uniprotkb:P35226 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851 psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831786|imex:IM-21659-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|uniprotkb:O00257(identity)|ddbj/embl/genbank:BC014967(identity)|entrezgene/locuslink:8535(identity) refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:P35226(identity)|entrezgene/locuslink:100532731(identity)|entrezgene/locuslink:648(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606 intact-crc:83BDF27C773B0D66|rigid:scMtP2CsXOhJNWLJ1RJ5Zhezv2Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00257 uniprotkb:P28288 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 intact:EBI-80992|ensembl:ENSP00000359233|uniprotkb:Q15271|uniprotkb:Q9H529|uniprotkb:Q6NUN5|uniprotkb:Q96DA3|uniprotkb:D3DT46 psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:abcd3_human(display_long)|uniprotkb:ABCD3(gene name)|psi-mi:ABCD3(display_short)|uniprotkb:PMP70(gene name synonym)|uniprotkb:PXMP1(gene name synonym)|uniprotkb:70 kDa peroxisomal membrane protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831786|imex:IM-21659-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|uniprotkb:O00257(identity)|ddbj/embl/genbank:BC014967(identity)|entrezgene/locuslink:8535(identity) ensembl:ENSG00000117528(gene)|ensembl:ENST00000370214(transcript)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0007031"(peroxisome organization)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042493"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|refseq:NP_001116146.1|refseq:NP_002849.1|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005283(Peroxysomal long chain fatty acyl transporter)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|mint:P28288|reactome:R-HSA-1369062|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9603798|uniprotkb:P28288(identity)|entrezgene/locuslink:5825(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 rogid:aUTR1BDihIx1JxtsC5V4vmFAwA49606 intact-crc:83BDF27C773B0D66|rigid:scMtP2CsXOhJNWLJ1RJ5Zhezv2Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00257 uniprotkb:P63208 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831786|imex:IM-21659-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|uniprotkb:O00257(identity)|ddbj/embl/genbank:BC014967(identity)|entrezgene/locuslink:8535(identity) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|entrezgene/locuslink:6500(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 intact-crc:83BDF27C773B0D66|rigid:scMtP2CsXOhJNWLJ1RJ5Zhezv2Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00257 uniprotkb:P23396 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 intact:EBI-351193|uniprotkb:Q498B5|uniprotkb:Q8NI95|uniprotkb:B2R7N5|ensembl:ENSP00000433821|ensembl:ENSP00000434643|ensembl:ENSP00000436971|uniprotkb:J3KN86 psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:rs3_human(display_long)|uniprotkb:RPS3(gene name)|psi-mi:RPS3(display_short)|uniprotkb:Small ribosomal subunit protein uS3(gene name synonym)|uniprotkb:OK/SW-cl.26(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831786|imex:IM-21659-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|uniprotkb:O00257(identity)|ddbj/embl/genbank:BC014967(identity)|entrezgene/locuslink:8535(identity) refseq:NP_000996.2|ensembl:ENSG00000149273(gene)|ensembl:ENST00000524851(transcript)|ensembl:ENST00000527446(transcript)|ensembl:ENST00000531188(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032357"(oxidized purine DNA binding)|go:"GO:0032358"(oxidized pyrimidine DNA binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045738"(negative regulation of DNA repair)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061481"(response to TNF agonist)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902546"(positive regulation of DNA N-glycosylase activity)|go:"GO:1905053"(positive regulation of base-excision repair)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001272"(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001351(Ribosomal protein S3, C-terminal)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR004044(K Homology, type 2)|go:"GO:0070301"(cellular response to hydrogen peroxide)|interpro:IPR005703(Ribosomal protein S3, eukaryotic/archaeal)|go:"GO:0071159"(NF-kappaB complex)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR015946(K homology-like, alpha/beta)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR018280|interpro:IPR036419|mint:P23396|rcsb pdb:1WH9|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|go:"GO:0072686"(mitotic spindle)|go:"GO:0097100"(supercoiled DNA binding)|rcsb pdb:6QZP|go:"GO:0140078"("class I DNA-(apurinic or apyrimidinic site) endonuclease activity")|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|refseq:NP_001243731.1|refseq:NP_001247436.1|refseq:NP_001247435.1|dip:DIP-33177N|uniprotkb:P23396(identity)|entrezgene/locuslink:6188(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 rogid:fsDW18AMR3YyEEIhMVcngYRWkps9606 intact-crc:83BDF27C773B0D66|rigid:scMtP2CsXOhJNWLJ1RJ5Zhezv2Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00257 uniprotkb:P78364 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 intact:EBI-725403|uniprotkb:Q8WVM3|uniprotkb:Q9BU63|uniprotkb:D3DUV4|ensembl:ENSP00000437659|ensembl:ENSP00000440674 psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:phc1_human(display_long)|uniprotkb:Early development regulatory protein 1(gene name synonym)|uniprotkb:PHC1(gene name)|psi-mi:PHC1(display_short)|uniprotkb:EDR1(gene name synonym)|uniprotkb:PH1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831786|imex:IM-21659-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|uniprotkb:O00257(identity)|ddbj/embl/genbank:BC014967(identity)|entrezgene/locuslink:8535(identity) refseq:NP_004417.2|ensembl:ENSG00000111752(gene)|ensembl:ENST00000543824(transcript)|ensembl:ENST00000544916(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:P78364|rcsb pdb:2L8E|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|dip:DIP-44567N|uniprotkb:P78364(identity)|entrezgene/locuslink:1911(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 rogid:0dDjrgvWcP5Sx8h+qUj7awuM3ko9606 intact-crc:83BDF27C773B0D66|rigid:scMtP2CsXOhJNWLJ1RJ5Zhezv2Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00257 uniprotkb:Q06587 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831786|imex:IM-21659-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|uniprotkb:O00257(identity)|ddbj/embl/genbank:BC014967(identity)|entrezgene/locuslink:8535(identity) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 intact-crc:83BDF27C773B0D66|rigid:scMtP2CsXOhJNWLJ1RJ5Zhezv2Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00257 uniprotkb:Q3KNV8 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 intact:EBI-2339807|uniprotkb:O15262|uniprotkb:D3DVN1|ensembl:ENSP00000354724|ensembl:ENSP00000420489 psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:pcgf3_human(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831786|imex:IM-21659-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|uniprotkb:O00257(identity)|ddbj/embl/genbank:BC014967(identity)|entrezgene/locuslink:8535(identity) refseq:NP_006306.2|refseq:NP_001304765.1|dip:DIP-52782N|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q3KNV8|uniprotkb:Q3KNV8(identity)|entrezgene/locuslink:10336(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606 intact-crc:83BDF27C773B0D66|rigid:scMtP2CsXOhJNWLJ1RJ5Zhezv2Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00257 uniprotkb:Q9BYE7 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831786|imex:IM-21659-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|uniprotkb:O00257(identity)|ddbj/embl/genbank:BC014967(identity)|entrezgene/locuslink:8535(identity) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 intact-crc:83BDF27C773B0D66|rigid:scMtP2CsXOhJNWLJ1RJ5Zhezv2Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00257 uniprotkb:Q86SE9 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492 psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831786|imex:IM-21659-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|uniprotkb:O00257(identity)|ddbj/embl/genbank:BC014967(identity)|entrezgene/locuslink:8535(identity) refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N|uniprotkb:Q86SE9(identity)|entrezgene/locuslink:84333(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606 intact-crc:83BDF27C773B0D66|rigid:scMtP2CsXOhJNWLJ1RJ5Zhezv2Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00257 uniprotkb:P61962 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831786|imex:IM-21659-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|uniprotkb:O00257(identity)|ddbj/embl/genbank:BC014967(identity)|entrezgene/locuslink:8535(identity) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 intact-crc:83BDF27C773B0D66|rigid:scMtP2CsXOhJNWLJ1RJ5Zhezv2Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00257 uniprotkb:Q04917 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 intact:EBI-306940|ensembl:ENSP00000248975|intact:EBI-11759595 psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:1433f_human(display_long)|uniprotkb:YWHAH(gene name)|psi-mi:YWHAH(display_short)|uniprotkb:YWHA1(gene name synonym)|uniprotkb:Protein AS1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831786|imex:IM-21659-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|uniprotkb:O00257(identity)|ddbj/embl/genbank:BC014967(identity)|entrezgene/locuslink:8535(identity) go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:Q04917|rcsb pdb:2C63|rcsb pdb:2C74|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|ensembl:ENSG00000128245(gene)|ensembl:ENST00000248975(transcript)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0003779"(actin binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006713"(glucocorticoid catabolic process)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0014704"(intercalated disc)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_003396.1|dip:DIP-27566N|uniprotkb:Q04917(identity)|entrezgene/locuslink:7533(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 rogid:VhFYPSsW3IRC388FTlmwwN37HnU9606 intact-crc:83BDF27C773B0D66|rigid:scMtP2CsXOhJNWLJ1RJ5Zhezv2Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00257 uniprotkb:O60762 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 intact:EBI-719526|uniprotkb:O15157|uniprotkb:Q96HK0|uniprotkb:Q6IB78|ensembl:ENSP00000360644 psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:dpm1_human(display_long)|uniprotkb:DPM1(gene name)|psi-mi:DPM1(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 1(gene name synonym)|uniprotkb:Dolichyl-phosphate beta-D-mannosyltransferase subunit 1(gene name synonym)|uniprotkb:Mannose-P-dolichol synthase subunit 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831786|imex:IM-21659-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|uniprotkb:O00257(identity)|ddbj/embl/genbank:BC014967(identity)|entrezgene/locuslink:8535(identity) refseq:NP_003850.1|refseq:NP_001303963.1|refseq:NP_001303964.1|refseq:NP_001303965.1|ensembl:ENSG00000000419(gene)|ensembl:ENST00000371588(transcript)|go:"GO:0004169"(dolichyl-phosphate-mannose-protein mannosyltransferase activity)|go:"GO:0004582"(dolichyl-phosphate beta-D-mannosyltransferase activity)|go:"GO:0005537"(mannose binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0019348"(dolichol metabolic process)|go:"GO:0019673"(GDP-mannose metabolic process)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035268"(protein mannosylation)|go:"GO:0035269"(protein O-linked mannosylation)|go:"GO:0043178"(alcohol binding)|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR029044|interpro:IPR039528|mint:O60762|reactome:R-HSA-162699|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377|uniprotkb:O60762(identity)|entrezgene/locuslink:8813(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 rogid:znbNDwp7t238ByanlbQzsTMvwTY9606 intact-crc:83BDF27C773B0D66|rigid:scMtP2CsXOhJNWLJ1RJ5Zhezv2Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00257 uniprotkb:Q9BSM1 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831786|imex:IM-21659-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|uniprotkb:O00257(identity)|ddbj/embl/genbank:BC014967(identity)|entrezgene/locuslink:8535(identity) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5|uniprotkb:Q9BSM1(identity)|entrezgene/locuslink:84759(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 intact-crc:83BDF27C773B0D66|rigid:scMtP2CsXOhJNWLJ1RJ5Zhezv2Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00257 uniprotkb:Q8NDX5 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 intact:EBI-1223801|uniprotkb:Q5HYF0|uniprotkb:Q6NSG2|uniprotkb:Q8NFT7|uniprotkb:Q8NFZ1|uniprotkb:Q8TBM2|uniprotkb:Q9H971|uniprotkb:Q9H9I4|uniprotkb:A2RRP9|ensembl:ENSP00000420271 psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:phc3_human(display_long)|uniprotkb:PHC3(gene name)|psi-mi:PHC3(display_short)|uniprotkb:EDR3(gene name synonym)|uniprotkb:PH3(gene name synonym)|uniprotkb:Homolog of polyhomeotic 3(gene name synonym)|uniprotkb:Early development regulatory protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831786|imex:IM-21659-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|uniprotkb:O00257(identity)|ddbj/embl/genbank:BC014967(identity)|entrezgene/locuslink:8535(identity) refseq:NP_079223.3|refseq:NP_001295045.1|ensembl:ENSP00000420271|ensembl:ENST00000495893|ensembl:ENSP00000420294|ensembl:ENST00000497658|ensembl:ENSP00000420454|ensembl:ENSG00000173889(gene)|ensembl:ENST00000494943(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:Q8NDX5|rcsb pdb:4PZN|rcsb pdb:4PZO|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q8NDX5(identity)|entrezgene/locuslink:80012(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 rogid:hB1EMs+lCv19uuJ1O7+QiVCUoo89606 intact-crc:83BDF27C773B0D66|rigid:scMtP2CsXOhJNWLJ1RJ5Zhezv2Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00257 uniprotkb:Q9UN30 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 intact:EBI-6911404|ensembl:ENSP00000369380|uniprotkb:B2RA08|uniprotkb:Q5H969|uniprotkb:B0FZN6|uniprotkb:Q5H968 psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:scml1_human(display_long)|uniprotkb:SCML1(gene name)|psi-mi:SCML1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831786|imex:IM-21659-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|uniprotkb:O00257(identity)|ddbj/embl/genbank:BC014967(identity)|entrezgene/locuslink:8535(identity) ensembl:ENSG00000047634(gene)|ensembl:ENST00000380041(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q9UN30|refseq:XP_016885212.1|refseq:XP_006724571.1|refseq:NP_001032624.1|refseq:NP_001032625.1|refseq:NP_001032629.1|refseq:NP_006737.2|uniprotkb:Q9UN30(identity)|entrezgene/locuslink:6322(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 rogid:/eJ/2Xuw4P5GzHy1wGRxnYZ4hvY9606 intact-crc:83BDF27C773B0D66|rigid:scMtP2CsXOhJNWLJ1RJ5Zhezv2Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00257 uniprotkb:Q8IXK0 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 intact:EBI-713786|uniprotkb:Q8N306|uniprotkb:Q8TAG8|uniprotkb:A1L4Q1|uniprotkb:Q2TAL3|uniprotkb:Q5T0C1|uniprotkb:Q6NUJ6|uniprotkb:Q6ZQR1|uniprotkb:Q96BL4|uniprotkb:Q9Y4Y7|ensembl:ENSP00000257118|uniprotkb:D3DPR2|uniprotkb:A8KA40 psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:phc2_human(display_long)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:PHC2(gene name)|psi-mi:PHC2(display_short)|uniprotkb:EDR2(gene name synonym)|uniprotkb:PH2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831786|imex:IM-21659-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|uniprotkb:O00257(identity)|ddbj/embl/genbank:BC014967(identity)|entrezgene/locuslink:8535(identity) interpro:IPR038603|mint:Q8IXK0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR013761(Sterile alpha motif-type)|ensembl:ENSG00000134686(gene)|ensembl:ENST00000257118(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|refseq:NP_004418.2|refseq:NP_932157.1|refseq:XP_016856005.1|refseq:XP_016856006.1|refseq:XP_016856007.1|refseq:XP_005270627.1|dip:DIP-34464N|uniprotkb:Q8IXK0(identity)|entrezgene/locuslink:1912(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 rogid:7si/KU2tHoxviuCr70ncQERDWmY9606 intact-crc:83BDF27C773B0D66|rigid:scMtP2CsXOhJNWLJ1RJ5Zhezv2Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00257 uniprotkb:P27348 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 intact:EBI-359854|uniprotkb:Q567U5|uniprotkb:Q5TZU8|uniprotkb:Q9UP48|uniprotkb:D6W4Z5|ensembl:ENSP00000238081|ensembl:ENSP00000371267 psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:1433t_human(display_long)|uniprotkb:YWHAQ(gene name)|psi-mi:YWHAQ(display_short)|uniprotkb:14-3-3 protein tau(gene name synonym)|uniprotkb:14-3-3 protein T-cell(gene name synonym)|uniprotkb:Protein HS1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831786|imex:IM-21659-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|uniprotkb:O00257(identity)|ddbj/embl/genbank:BC014967(identity)|entrezgene/locuslink:8535(identity) refseq:NP_006817.1|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034766"(negative regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071889"(14-3-3 protein binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|interpro:IPR042584|mint:P27348|rcsb pdb:2BTP|rcsb pdb:5IQP|rcsb pdb:6BCR|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6KZG|rcsb pdb:6KZH|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9614399|ensembl:ENSG00000134308(gene)|ensembl:ENST00000238081(transcript)|ensembl:ENST00000381844(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008022"(protein C-terminus binding)|dip:DIP-27584N|uniprotkb:P27348(identity)|entrezgene/locuslink:10971(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 rogid:3I07h/wy8qcwUJqvO1RA76qnW5U9606 intact-crc:83BDF27C773B0D66|rigid:scMtP2CsXOhJNWLJ1RJ5Zhezv2Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00257 uniprotkb:Q9HAH7 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 intact:EBI-2847800|uniprotkb:Q9H9X4|uniprotkb:Q96CI9|uniprotkb:B4DP86|ensembl:ENSP00000287468 psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:fbrs_human(display_long)|uniprotkb:FBRS(gene name)|psi-mi:FBRS(display_short)|uniprotkb:FBS(gene name synonym)|uniprotkb:FBS1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831786|imex:IM-21659-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|uniprotkb:O00257(identity)|ddbj/embl/genbank:BC014967(identity)|entrezgene/locuslink:8535(identity) refseq:NP_001098549.2|dip:DIP-61357N|ensembl:ENSG00000156860(gene)|ensembl:ENST00000287468(transcript)|interpro:IPR023246|mint:Q9HAH7|uniprotkb:Q9HAH7(identity)|entrezgene/locuslink:64319(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 rogid:n1zkWAYdgwY+t7CFWg5RKO1VSfE9606 intact-crc:83BDF27C773B0D66|rigid:scMtP2CsXOhJNWLJ1RJ5Zhezv2Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00257 uniprotkb:Q9BQE3 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8831786|imex:IM-21659-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|uniprotkb:O00257(identity)|ddbj/embl/genbank:BC014967(identity)|entrezgene/locuslink:8535(identity) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1|uniprotkb:Q9BQE3(identity)|entrezgene/locuslink:84790(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:83BDF27C773B0D66|rigid:scMtP2CsXOhJNWLJ1RJ5Zhezv2Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95503 uniprotkb:P78364 intact:EBI-3951758|uniprotkb:A8KAH0|uniprotkb:Q96EM5|intact:EBI-28986885|ensembl:ENSP00000384490 intact:EBI-725403|uniprotkb:Q8WVM3|uniprotkb:Q9BU63|uniprotkb:D3DUV4|ensembl:ENSP00000437659|ensembl:ENSP00000440674 psi-mi:cbx6_human(display_long)|uniprotkb:CBX6(gene name)|psi-mi:CBX6(display_short) psi-mi:phc1_human(display_long)|uniprotkb:Early development regulatory protein 1(gene name synonym)|uniprotkb:PHC1(gene name)|psi-mi:PHC1(display_short)|uniprotkb:EDR1(gene name synonym)|uniprotkb:PH1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832043|imex:IM-21659-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001290423.1|ensembl:ENSG00000183741(gene)|refseq:NP_055107.3|ensembl:ENST00000407418(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:O95503|rcsb pdb:3GV6|rcsb pdb:3I90|reactome:R-HSA-2559580|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSP00000384490|dip:DIP-48605N|uniprotkb:O95503(identity)|ddbj/embl/genbank:BC064900(identity)|entrezgene/locuslink:23466(identity) refseq:NP_004417.2|ensembl:ENSG00000111752(gene)|ensembl:ENST00000543824(transcript)|ensembl:ENST00000544916(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:P78364|rcsb pdb:2L8E|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|dip:DIP-44567N|uniprotkb:P78364(identity)|entrezgene/locuslink:1911(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:4iNHCYe1bjb/JcurXP1iGoO/2uA9606 rogid:0dDjrgvWcP5Sx8h+qUj7awuM3ko9606 intact-crc:D2FE0DBE4E93CFBB|rigid:SUfLwYEWLHNb1mgxerK08cYHlys false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95503 uniprotkb:Q9UN30 intact:EBI-3951758|uniprotkb:A8KAH0|uniprotkb:Q96EM5|intact:EBI-28986885|ensembl:ENSP00000384490 intact:EBI-6911404|ensembl:ENSP00000369380|uniprotkb:B2RA08|uniprotkb:Q5H969|uniprotkb:B0FZN6|uniprotkb:Q5H968 psi-mi:cbx6_human(display_long)|uniprotkb:CBX6(gene name)|psi-mi:CBX6(display_short) psi-mi:scml1_human(display_long)|uniprotkb:SCML1(gene name)|psi-mi:SCML1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832043|imex:IM-21659-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001290423.1|ensembl:ENSG00000183741(gene)|refseq:NP_055107.3|ensembl:ENST00000407418(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:O95503|rcsb pdb:3GV6|rcsb pdb:3I90|reactome:R-HSA-2559580|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSP00000384490|dip:DIP-48605N|uniprotkb:O95503(identity)|ddbj/embl/genbank:BC064900(identity)|entrezgene/locuslink:23466(identity) ensembl:ENSG00000047634(gene)|ensembl:ENST00000380041(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q9UN30|refseq:XP_016885212.1|refseq:XP_006724571.1|refseq:NP_001032624.1|refseq:NP_001032625.1|refseq:NP_001032629.1|refseq:NP_006737.2|uniprotkb:Q9UN30(identity)|entrezgene/locuslink:6322(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:4iNHCYe1bjb/JcurXP1iGoO/2uA9606 rogid:/eJ/2Xuw4P5GzHy1wGRxnYZ4hvY9606 intact-crc:D2FE0DBE4E93CFBB|rigid:SUfLwYEWLHNb1mgxerK08cYHlys false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95503 uniprotkb:P35226 intact:EBI-3951758|uniprotkb:A8KAH0|uniprotkb:Q96EM5|intact:EBI-28986885|ensembl:ENSP00000384490 intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851 psi-mi:cbx6_human(display_long)|uniprotkb:CBX6(gene name)|psi-mi:CBX6(display_short) psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832043|imex:IM-21659-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001290423.1|ensembl:ENSG00000183741(gene)|refseq:NP_055107.3|ensembl:ENST00000407418(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:O95503|rcsb pdb:3GV6|rcsb pdb:3I90|reactome:R-HSA-2559580|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSP00000384490|dip:DIP-48605N|uniprotkb:O95503(identity)|ddbj/embl/genbank:BC064900(identity)|entrezgene/locuslink:23466(identity) refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:P35226(identity)|entrezgene/locuslink:100532731(identity)|entrezgene/locuslink:648(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:4iNHCYe1bjb/JcurXP1iGoO/2uA9606 rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606 intact-crc:D2FE0DBE4E93CFBB|rigid:SUfLwYEWLHNb1mgxerK08cYHlys false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95503 uniprotkb:Q3ZCQ8 intact:EBI-3951758|uniprotkb:A8KAH0|uniprotkb:Q96EM5|intact:EBI-28986885|ensembl:ENSP00000384490 intact:EBI-355175|uniprotkb:Q6QA00|uniprotkb:Q96FJ5|uniprotkb:Q96GY2|uniprotkb:Q9H370|intact:EBI-2554785|uniprotkb:Q330K1|ensembl:ENSP00000475531 psi-mi:cbx6_human(display_long)|uniprotkb:CBX6(gene name)|psi-mi:CBX6(display_short) psi-mi:tim50_human(display_long)|uniprotkb:TIMM50(gene name)|psi-mi:TIMM50(display_short)|uniprotkb:TIM50(gene name synonym)|uniprotkb:PRO1512(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832043|imex:IM-21659-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001290423.1|ensembl:ENSG00000183741(gene)|refseq:NP_055107.3|ensembl:ENST00000407418(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:O95503|rcsb pdb:3GV6|rcsb pdb:3I90|reactome:R-HSA-2559580|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSP00000384490|dip:DIP-48605N|uniprotkb:O95503(identity)|ddbj/embl/genbank:BC064900(identity)|entrezgene/locuslink:23466(identity) refseq:NP_001001563.1|ensembl:ENSG00000105197(gene)|ensembl:ENST00000607714(transcript)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003723"(RNA binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005134"(interleukin-2 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007006"(mitochondrial membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR004274(NLI interacting factor)|interpro:IPR023214|interpro:IPR027111|interpro:IPR036412|mint:Q3ZCQ8|reactome:R-HSA-1268020|refseq:NP_001316488.1|dip:DIP-34058N|uniprotkb:Q3ZCQ8(identity)|entrezgene/locuslink:92609(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:4iNHCYe1bjb/JcurXP1iGoO/2uA9606 rogid:fOPV33h12YhAq9jj0bVno01Q+6g9606 intact-crc:D2FE0DBE4E93CFBB|rigid:SUfLwYEWLHNb1mgxerK08cYHlys false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95503 uniprotkb:Q7Z417 intact:EBI-3951758|uniprotkb:A8KAH0|uniprotkb:Q96EM5|intact:EBI-28986885|ensembl:ENSP00000384490 intact:EBI-1210753|intact:EBI-10172018|uniprotkb:A1L3A7|uniprotkb:Q9P2M5|uniprotkb:A1L3A6|ensembl:ENSP00000225388 psi-mi:cbx6_human(display_long)|uniprotkb:CBX6(gene name)|psi-mi:CBX6(display_short) psi-mi:nufp2_human(display_long)|uniprotkb:NUFIP2(gene name)|psi-mi:NUFIP2(display_short)|uniprotkb:KIAA1321(gene name synonym)|uniprotkb:PIG1(orf name)|uniprotkb:FMRP-interacting protein 2(gene name synonym)|uniprotkb:82 kDa FMRP-interacting protein(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 1 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832043|imex:IM-21659-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001290423.1|ensembl:ENSG00000183741(gene)|refseq:NP_055107.3|ensembl:ENST00000407418(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:O95503|rcsb pdb:3GV6|rcsb pdb:3I90|reactome:R-HSA-2559580|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSP00000384490|dip:DIP-48605N|uniprotkb:O95503(identity)|ddbj/embl/genbank:BC064900(identity)|entrezgene/locuslink:23466(identity) refseq:NP_065823.1|dip:DIP-29023N|ensembl:ENSG00000108256(gene)|ensembl:ENST00000225388(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR032747|mint:Q7Z417|uniprotkb:Q7Z417(identity)|entrezgene/locuslink:57532(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:4iNHCYe1bjb/JcurXP1iGoO/2uA9606 rogid:zdbkRisveP+8g70umfbEPHTnAgk9606 intact-crc:D2FE0DBE4E93CFBB|rigid:SUfLwYEWLHNb1mgxerK08cYHlys false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95503 uniprotkb:P27635 intact:EBI-3951758|uniprotkb:A8KAH0|uniprotkb:Q96EM5|intact:EBI-28986885|ensembl:ENSP00000384490 intact:EBI-352398|uniprotkb:A3KQT0|uniprotkb:Q16470|uniprotkb:Q2HXT7|uniprotkb:Q53FH7|uniprotkb:Q6FGN8|uniprotkb:Q8TDA5|intact:EBI-3046680|uniprotkb:D3DWW6|ensembl:ENSP00000341730|ensembl:ENSP00000358832 psi-mi:cbx6_human(display_long)|uniprotkb:CBX6(gene name)|psi-mi:CBX6(display_short) psi-mi:rl10_human(display_long)|uniprotkb:RPL10(gene name)|psi-mi:RPL10(display_short)|uniprotkb:QM(gene name synonym)|uniprotkb:Protein QM(gene name synonym)|uniprotkb:Tumor suppressor QM(gene name synonym)|uniprotkb:Laminin receptor homolog(gene name synonym)|uniprotkb:DXS648E(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL16(gene name synonym)|uniprotkb:Ribosomal protein L10(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832043|imex:IM-21659-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001290423.1|ensembl:ENSG00000183741(gene)|refseq:NP_055107.3|ensembl:ENST00000407418(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:O95503|rcsb pdb:3GV6|rcsb pdb:3I90|reactome:R-HSA-2559580|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSP00000384490|dip:DIP-48605N|uniprotkb:O95503(identity)|ddbj/embl/genbank:BC064900(identity)|entrezgene/locuslink:23466(identity) refseq:NP_001243506.2|refseq:NP_001243509.2|refseq:NP_001290553.1|refseq:NP_001290554.1|refseq:NP_001290555.1|ensembl:ENSG00000147403(gene)|ensembl:ENST00000344746(transcript)|ensembl:ENST00000369817(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006417"(regulation of translation)|refseq:NP_006004.3|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045182"(translation regulator activity)|go:"GO:1990403"(embryonic brain development)|interpro:IPR001197(Ribosomal protein L10e)|interpro:IPR016180(Ribosomal protein L10e/L16)|interpro:IPR018255|interpro:IPR036920|mint:P27635|rcsb pdb:2PA2|rcsb pdb:5AJ0|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6W6L|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|go:"GO:0016020"(membrane)|reactome:R-HSA-975957|dip:DIP-1133N|uniprotkb:P27635(identity)|entrezgene/locuslink:6134(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:4iNHCYe1bjb/JcurXP1iGoO/2uA9606 rogid:wJnBcv39yvVz2CaZq8UKgxIpJeE9606 intact-crc:D2FE0DBE4E93CFBB|rigid:SUfLwYEWLHNb1mgxerK08cYHlys false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95503 uniprotkb:Q8NDX5 intact:EBI-3951758|uniprotkb:A8KAH0|uniprotkb:Q96EM5|intact:EBI-28986885|ensembl:ENSP00000384490 intact:EBI-1223801|uniprotkb:Q5HYF0|uniprotkb:Q6NSG2|uniprotkb:Q8NFT7|uniprotkb:Q8NFZ1|uniprotkb:Q8TBM2|uniprotkb:Q9H971|uniprotkb:Q9H9I4|uniprotkb:A2RRP9|ensembl:ENSP00000420271 psi-mi:cbx6_human(display_long)|uniprotkb:CBX6(gene name)|psi-mi:CBX6(display_short) psi-mi:phc3_human(display_long)|uniprotkb:PHC3(gene name)|psi-mi:PHC3(display_short)|uniprotkb:EDR3(gene name synonym)|uniprotkb:PH3(gene name synonym)|uniprotkb:Homolog of polyhomeotic 3(gene name synonym)|uniprotkb:Early development regulatory protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832043|imex:IM-21659-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001290423.1|ensembl:ENSG00000183741(gene)|refseq:NP_055107.3|ensembl:ENST00000407418(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:O95503|rcsb pdb:3GV6|rcsb pdb:3I90|reactome:R-HSA-2559580|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSP00000384490|dip:DIP-48605N|uniprotkb:O95503(identity)|ddbj/embl/genbank:BC064900(identity)|entrezgene/locuslink:23466(identity) refseq:NP_079223.3|refseq:NP_001295045.1|ensembl:ENSP00000420271|ensembl:ENST00000495893|ensembl:ENSP00000420294|ensembl:ENST00000497658|ensembl:ENSP00000420454|ensembl:ENSG00000173889(gene)|ensembl:ENST00000494943(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:Q8NDX5|rcsb pdb:4PZN|rcsb pdb:4PZO|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q8NDX5(identity)|entrezgene/locuslink:80012(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:4iNHCYe1bjb/JcurXP1iGoO/2uA9606 rogid:hB1EMs+lCv19uuJ1O7+QiVCUoo89606 intact-crc:D2FE0DBE4E93CFBB|rigid:SUfLwYEWLHNb1mgxerK08cYHlys false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95503 uniprotkb:Q8IXK0 intact:EBI-3951758|uniprotkb:A8KAH0|uniprotkb:Q96EM5|intact:EBI-28986885|ensembl:ENSP00000384490 intact:EBI-713786|uniprotkb:Q8N306|uniprotkb:Q8TAG8|uniprotkb:A1L4Q1|uniprotkb:Q2TAL3|uniprotkb:Q5T0C1|uniprotkb:Q6NUJ6|uniprotkb:Q6ZQR1|uniprotkb:Q96BL4|uniprotkb:Q9Y4Y7|ensembl:ENSP00000257118|uniprotkb:D3DPR2|uniprotkb:A8KA40 psi-mi:cbx6_human(display_long)|uniprotkb:CBX6(gene name)|psi-mi:CBX6(display_short) psi-mi:phc2_human(display_long)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:PHC2(gene name)|psi-mi:PHC2(display_short)|uniprotkb:EDR2(gene name synonym)|uniprotkb:PH2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832043|imex:IM-21659-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001290423.1|ensembl:ENSG00000183741(gene)|refseq:NP_055107.3|ensembl:ENST00000407418(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:O95503|rcsb pdb:3GV6|rcsb pdb:3I90|reactome:R-HSA-2559580|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSP00000384490|dip:DIP-48605N|uniprotkb:O95503(identity)|ddbj/embl/genbank:BC064900(identity)|entrezgene/locuslink:23466(identity) interpro:IPR038603|mint:Q8IXK0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR013761(Sterile alpha motif-type)|ensembl:ENSG00000134686(gene)|ensembl:ENST00000257118(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|refseq:NP_004418.2|refseq:NP_932157.1|refseq:XP_016856005.1|refseq:XP_016856006.1|refseq:XP_016856007.1|refseq:XP_005270627.1|dip:DIP-34464N|uniprotkb:Q8IXK0(identity)|entrezgene/locuslink:1912(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:4iNHCYe1bjb/JcurXP1iGoO/2uA9606 rogid:7si/KU2tHoxviuCr70ncQERDWmY9606 intact-crc:D2FE0DBE4E93CFBB|rigid:SUfLwYEWLHNb1mgxerK08cYHlys false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95503 uniprotkb:Q06587 intact:EBI-3951758|uniprotkb:A8KAH0|uniprotkb:Q96EM5|intact:EBI-28986885|ensembl:ENSP00000384490 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 psi-mi:cbx6_human(display_long)|uniprotkb:CBX6(gene name)|psi-mi:CBX6(display_short) psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832043|imex:IM-21659-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001290423.1|ensembl:ENSG00000183741(gene)|refseq:NP_055107.3|ensembl:ENST00000407418(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:O95503|rcsb pdb:3GV6|rcsb pdb:3I90|reactome:R-HSA-2559580|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSP00000384490|dip:DIP-48605N|uniprotkb:O95503(identity)|ddbj/embl/genbank:BC064900(identity)|entrezgene/locuslink:23466(identity) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:4iNHCYe1bjb/JcurXP1iGoO/2uA9606 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 intact-crc:D2FE0DBE4E93CFBB|rigid:SUfLwYEWLHNb1mgxerK08cYHlys false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95503 uniprotkb:P23396 intact:EBI-3951758|uniprotkb:A8KAH0|uniprotkb:Q96EM5|intact:EBI-28986885|ensembl:ENSP00000384490 intact:EBI-351193|uniprotkb:Q498B5|uniprotkb:Q8NI95|uniprotkb:B2R7N5|ensembl:ENSP00000433821|ensembl:ENSP00000434643|ensembl:ENSP00000436971|uniprotkb:J3KN86 psi-mi:cbx6_human(display_long)|uniprotkb:CBX6(gene name)|psi-mi:CBX6(display_short) psi-mi:rs3_human(display_long)|uniprotkb:RPS3(gene name)|psi-mi:RPS3(display_short)|uniprotkb:Small ribosomal subunit protein uS3(gene name synonym)|uniprotkb:OK/SW-cl.26(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832043|imex:IM-21659-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001290423.1|ensembl:ENSG00000183741(gene)|refseq:NP_055107.3|ensembl:ENST00000407418(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:O95503|rcsb pdb:3GV6|rcsb pdb:3I90|reactome:R-HSA-2559580|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSP00000384490|dip:DIP-48605N|uniprotkb:O95503(identity)|ddbj/embl/genbank:BC064900(identity)|entrezgene/locuslink:23466(identity) refseq:NP_000996.2|ensembl:ENSG00000149273(gene)|ensembl:ENST00000524851(transcript)|ensembl:ENST00000527446(transcript)|ensembl:ENST00000531188(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032357"(oxidized purine DNA binding)|go:"GO:0032358"(oxidized pyrimidine DNA binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045738"(negative regulation of DNA repair)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061481"(response to TNF agonist)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902546"(positive regulation of DNA N-glycosylase activity)|go:"GO:1905053"(positive regulation of base-excision repair)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001272"(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001351(Ribosomal protein S3, C-terminal)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR004044(K Homology, type 2)|go:"GO:0070301"(cellular response to hydrogen peroxide)|interpro:IPR005703(Ribosomal protein S3, eukaryotic/archaeal)|go:"GO:0071159"(NF-kappaB complex)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR015946(K homology-like, alpha/beta)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR018280|interpro:IPR036419|mint:P23396|rcsb pdb:1WH9|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|go:"GO:0072686"(mitotic spindle)|go:"GO:0097100"(supercoiled DNA binding)|rcsb pdb:6QZP|go:"GO:0140078"("class I DNA-(apurinic or apyrimidinic site) endonuclease activity")|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|refseq:NP_001243731.1|refseq:NP_001247436.1|refseq:NP_001247435.1|dip:DIP-33177N|uniprotkb:P23396(identity)|entrezgene/locuslink:6188(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:4iNHCYe1bjb/JcurXP1iGoO/2uA9606 rogid:fsDW18AMR3YyEEIhMVcngYRWkps9606 intact-crc:D2FE0DBE4E93CFBB|rigid:SUfLwYEWLHNb1mgxerK08cYHlys false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95503 uniprotkb:P61962 intact:EBI-3951758|uniprotkb:A8KAH0|uniprotkb:Q96EM5|intact:EBI-28986885|ensembl:ENSP00000384490 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 psi-mi:cbx6_human(display_long)|uniprotkb:CBX6(gene name)|psi-mi:CBX6(display_short) psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832043|imex:IM-21659-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001290423.1|ensembl:ENSG00000183741(gene)|refseq:NP_055107.3|ensembl:ENST00000407418(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:O95503|rcsb pdb:3GV6|rcsb pdb:3I90|reactome:R-HSA-2559580|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSP00000384490|dip:DIP-48605N|uniprotkb:O95503(identity)|ddbj/embl/genbank:BC064900(identity)|entrezgene/locuslink:23466(identity) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:4iNHCYe1bjb/JcurXP1iGoO/2uA9606 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 intact-crc:D2FE0DBE4E93CFBB|rigid:SUfLwYEWLHNb1mgxerK08cYHlys false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95503 uniprotkb:Q9BQE3 intact:EBI-3951758|uniprotkb:A8KAH0|uniprotkb:Q96EM5|intact:EBI-28986885|ensembl:ENSP00000384490 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:cbx6_human(display_long)|uniprotkb:CBX6(gene name)|psi-mi:CBX6(display_short) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832043|imex:IM-21659-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001290423.1|ensembl:ENSG00000183741(gene)|refseq:NP_055107.3|ensembl:ENST00000407418(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:O95503|rcsb pdb:3GV6|rcsb pdb:3I90|reactome:R-HSA-2559580|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSP00000384490|dip:DIP-48605N|uniprotkb:O95503(identity)|ddbj/embl/genbank:BC064900(identity)|entrezgene/locuslink:23466(identity) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1|uniprotkb:Q9BQE3(identity)|entrezgene/locuslink:84790(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:4iNHCYe1bjb/JcurXP1iGoO/2uA9606 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:D2FE0DBE4E93CFBB|rigid:SUfLwYEWLHNb1mgxerK08cYHlys false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95503 uniprotkb:Q99496 intact:EBI-3951758|uniprotkb:A8KAH0|uniprotkb:Q96EM5|intact:EBI-28986885|ensembl:ENSP00000384490 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:cbx6_human(display_long)|uniprotkb:CBX6(gene name)|psi-mi:CBX6(display_short) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832043|imex:IM-21659-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001290423.1|ensembl:ENSG00000183741(gene)|refseq:NP_055107.3|ensembl:ENST00000407418(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:O95503|rcsb pdb:3GV6|rcsb pdb:3I90|reactome:R-HSA-2559580|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSP00000384490|dip:DIP-48605N|uniprotkb:O95503(identity)|ddbj/embl/genbank:BC064900(identity)|entrezgene/locuslink:23466(identity) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|entrezgene/locuslink:6045(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:4iNHCYe1bjb/JcurXP1iGoO/2uA9606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 intact-crc:D2FE0DBE4E93CFBB|rigid:SUfLwYEWLHNb1mgxerK08cYHlys false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95931 uniprotkb:P35227 intact:EBI-3923843|uniprotkb:Q86T17|ensembl:ENSP00000216133 intact:EBI-2129767|uniprotkb:A6NGD8|ensembl:ENSP00000478517|ensembl:ENSP00000478970|ensembl:ENSP00000482063|ensembl:ENSP00000482815|ensembl:ENSP00000488868|ensembl:ENSP00000488872 psi-mi:cbx7_human(display_long)|uniprotkb:CBX7(gene name)|psi-mi:CBX7(display_short) psi-mi:pcgf2_human(display_long)|uniprotkb:PCGF2(gene name)|psi-mi:PCGF2(display_short)|uniprotkb:MEL18(gene name synonym)|uniprotkb:RNF110(gene name synonym)|uniprotkb:ZNF144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832106|imex:IM-21659-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783640.1|ensembl:ENSG00000100307(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|mint:O95931|rcsb pdb:2K1B|rcsb pdb:2L12|rcsb pdb:2L1B|rcsb pdb:3GS2|rcsb pdb:4MN3|rcsb pdb:5EPJ|rcsb pdb:6V2R|ensembl:ENST00000216133(transcript)|dip:DIP-44565N|uniprotkb:O95931(identity)|ddbj/embl/genbank:BC051773(identity)|entrezgene/locuslink:23492(identity) refseq:NP_009075.1|refseq:XP_016880505.1|refseq:XP_005257697.1|refseq:XP_005257698.1|refseq:XP_005257699.1|dip:DIP-41880N|ensembl:ENSG00000277258(gene)|ensembl:ENSG00000278644(gene)|ensembl:ENST00000610440(transcript)|ensembl:ENST00000611883(transcript)|ensembl:ENST00000616199(transcript)|ensembl:ENST00000620225(transcript)|ensembl:ENST00000631566(transcript)|ensembl:ENST00000631610(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35227|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-5617472|reactome:R-HSA-8953750|uniprotkb:P35227(identity)|entrezgene/locuslink:7703(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:LDXV9srMj1BL2CaSSot1Bn0/EW49606 rogid:zppw56VrEl6gEFwtJMCN5cQkPxI9606 intact-crc:D5DA4700F11A7C29|rigid:HltlO5z8HGhhVHPnebe0ERkbqc4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95931 uniprotkb:Q06587 intact:EBI-3923843|uniprotkb:Q86T17|ensembl:ENSP00000216133 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 psi-mi:cbx7_human(display_long)|uniprotkb:CBX7(gene name)|psi-mi:CBX7(display_short) psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832106|imex:IM-21659-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783640.1|ensembl:ENSG00000100307(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|mint:O95931|rcsb pdb:2K1B|rcsb pdb:2L12|rcsb pdb:2L1B|rcsb pdb:3GS2|rcsb pdb:4MN3|rcsb pdb:5EPJ|rcsb pdb:6V2R|ensembl:ENST00000216133(transcript)|dip:DIP-44565N|uniprotkb:O95931(identity)|ddbj/embl/genbank:BC051773(identity)|entrezgene/locuslink:23492(identity) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:LDXV9srMj1BL2CaSSot1Bn0/EW49606 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 intact-crc:D5DA4700F11A7C29|rigid:HltlO5z8HGhhVHPnebe0ERkbqc4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95931 uniprotkb:Q7Z417 intact:EBI-3923843|uniprotkb:Q86T17|ensembl:ENSP00000216133 intact:EBI-1210753|intact:EBI-10172018|uniprotkb:A1L3A7|uniprotkb:Q9P2M5|uniprotkb:A1L3A6|ensembl:ENSP00000225388 psi-mi:cbx7_human(display_long)|uniprotkb:CBX7(gene name)|psi-mi:CBX7(display_short) psi-mi:nufp2_human(display_long)|uniprotkb:NUFIP2(gene name)|psi-mi:NUFIP2(display_short)|uniprotkb:KIAA1321(gene name synonym)|uniprotkb:PIG1(orf name)|uniprotkb:FMRP-interacting protein 2(gene name synonym)|uniprotkb:82 kDa FMRP-interacting protein(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 1 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832106|imex:IM-21659-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783640.1|ensembl:ENSG00000100307(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|mint:O95931|rcsb pdb:2K1B|rcsb pdb:2L12|rcsb pdb:2L1B|rcsb pdb:3GS2|rcsb pdb:4MN3|rcsb pdb:5EPJ|rcsb pdb:6V2R|ensembl:ENST00000216133(transcript)|dip:DIP-44565N|uniprotkb:O95931(identity)|ddbj/embl/genbank:BC051773(identity)|entrezgene/locuslink:23492(identity) refseq:NP_065823.1|dip:DIP-29023N|ensembl:ENSG00000108256(gene)|ensembl:ENST00000225388(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR032747|mint:Q7Z417|uniprotkb:Q7Z417(identity)|entrezgene/locuslink:57532(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:LDXV9srMj1BL2CaSSot1Bn0/EW49606 rogid:zdbkRisveP+8g70umfbEPHTnAgk9606 intact-crc:D5DA4700F11A7C29|rigid:HltlO5z8HGhhVHPnebe0ERkbqc4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95931 uniprotkb:Q9BQE3 intact:EBI-3923843|uniprotkb:Q86T17|ensembl:ENSP00000216133 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:cbx7_human(display_long)|uniprotkb:CBX7(gene name)|psi-mi:CBX7(display_short) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832106|imex:IM-21659-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783640.1|ensembl:ENSG00000100307(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|mint:O95931|rcsb pdb:2K1B|rcsb pdb:2L12|rcsb pdb:2L1B|rcsb pdb:3GS2|rcsb pdb:4MN3|rcsb pdb:5EPJ|rcsb pdb:6V2R|ensembl:ENST00000216133(transcript)|dip:DIP-44565N|uniprotkb:O95931(identity)|ddbj/embl/genbank:BC051773(identity)|entrezgene/locuslink:23492(identity) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1|uniprotkb:Q9BQE3(identity)|entrezgene/locuslink:84790(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:LDXV9srMj1BL2CaSSot1Bn0/EW49606 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:D5DA4700F11A7C29|rigid:HltlO5z8HGhhVHPnebe0ERkbqc4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95931 uniprotkb:Q8NDX5 intact:EBI-3923843|uniprotkb:Q86T17|ensembl:ENSP00000216133 intact:EBI-1223801|uniprotkb:Q5HYF0|uniprotkb:Q6NSG2|uniprotkb:Q8NFT7|uniprotkb:Q8NFZ1|uniprotkb:Q8TBM2|uniprotkb:Q9H971|uniprotkb:Q9H9I4|uniprotkb:A2RRP9|ensembl:ENSP00000420271 psi-mi:cbx7_human(display_long)|uniprotkb:CBX7(gene name)|psi-mi:CBX7(display_short) psi-mi:phc3_human(display_long)|uniprotkb:PHC3(gene name)|psi-mi:PHC3(display_short)|uniprotkb:EDR3(gene name synonym)|uniprotkb:PH3(gene name synonym)|uniprotkb:Homolog of polyhomeotic 3(gene name synonym)|uniprotkb:Early development regulatory protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832106|imex:IM-21659-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783640.1|ensembl:ENSG00000100307(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|mint:O95931|rcsb pdb:2K1B|rcsb pdb:2L12|rcsb pdb:2L1B|rcsb pdb:3GS2|rcsb pdb:4MN3|rcsb pdb:5EPJ|rcsb pdb:6V2R|ensembl:ENST00000216133(transcript)|dip:DIP-44565N|uniprotkb:O95931(identity)|ddbj/embl/genbank:BC051773(identity)|entrezgene/locuslink:23492(identity) refseq:NP_079223.3|refseq:NP_001295045.1|ensembl:ENSP00000420271|ensembl:ENST00000495893|ensembl:ENSP00000420294|ensembl:ENST00000497658|ensembl:ENSP00000420454|ensembl:ENSG00000173889(gene)|ensembl:ENST00000494943(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:Q8NDX5|rcsb pdb:4PZN|rcsb pdb:4PZO|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q8NDX5(identity)|entrezgene/locuslink:80012(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:LDXV9srMj1BL2CaSSot1Bn0/EW49606 rogid:hB1EMs+lCv19uuJ1O7+QiVCUoo89606 intact-crc:D5DA4700F11A7C29|rigid:HltlO5z8HGhhVHPnebe0ERkbqc4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95931 uniprotkb:Q9BYE7 intact:EBI-3923843|uniprotkb:Q86T17|ensembl:ENSP00000216133 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 psi-mi:cbx7_human(display_long)|uniprotkb:CBX7(gene name)|psi-mi:CBX7(display_short) psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832106|imex:IM-21659-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783640.1|ensembl:ENSG00000100307(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|mint:O95931|rcsb pdb:2K1B|rcsb pdb:2L12|rcsb pdb:2L1B|rcsb pdb:3GS2|rcsb pdb:4MN3|rcsb pdb:5EPJ|rcsb pdb:6V2R|ensembl:ENST00000216133(transcript)|dip:DIP-44565N|uniprotkb:O95931(identity)|ddbj/embl/genbank:BC051773(identity)|entrezgene/locuslink:23492(identity) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:LDXV9srMj1BL2CaSSot1Bn0/EW49606 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 intact-crc:D5DA4700F11A7C29|rigid:HltlO5z8HGhhVHPnebe0ERkbqc4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95931 uniprotkb:Q99496 intact:EBI-3923843|uniprotkb:Q86T17|ensembl:ENSP00000216133 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:cbx7_human(display_long)|uniprotkb:CBX7(gene name)|psi-mi:CBX7(display_short) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832106|imex:IM-21659-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783640.1|ensembl:ENSG00000100307(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|mint:O95931|rcsb pdb:2K1B|rcsb pdb:2L12|rcsb pdb:2L1B|rcsb pdb:3GS2|rcsb pdb:4MN3|rcsb pdb:5EPJ|rcsb pdb:6V2R|ensembl:ENST00000216133(transcript)|dip:DIP-44565N|uniprotkb:O95931(identity)|ddbj/embl/genbank:BC051773(identity)|entrezgene/locuslink:23492(identity) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|entrezgene/locuslink:6045(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:LDXV9srMj1BL2CaSSot1Bn0/EW49606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 intact-crc:D5DA4700F11A7C29|rigid:HltlO5z8HGhhVHPnebe0ERkbqc4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95931 uniprotkb:Q3ZCQ8 intact:EBI-3923843|uniprotkb:Q86T17|ensembl:ENSP00000216133 intact:EBI-355175|uniprotkb:Q6QA00|uniprotkb:Q96FJ5|uniprotkb:Q96GY2|uniprotkb:Q9H370|intact:EBI-2554785|uniprotkb:Q330K1|ensembl:ENSP00000475531 psi-mi:cbx7_human(display_long)|uniprotkb:CBX7(gene name)|psi-mi:CBX7(display_short) psi-mi:tim50_human(display_long)|uniprotkb:TIMM50(gene name)|psi-mi:TIMM50(display_short)|uniprotkb:TIM50(gene name synonym)|uniprotkb:PRO1512(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832106|imex:IM-21659-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783640.1|ensembl:ENSG00000100307(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|mint:O95931|rcsb pdb:2K1B|rcsb pdb:2L12|rcsb pdb:2L1B|rcsb pdb:3GS2|rcsb pdb:4MN3|rcsb pdb:5EPJ|rcsb pdb:6V2R|ensembl:ENST00000216133(transcript)|dip:DIP-44565N|uniprotkb:O95931(identity)|ddbj/embl/genbank:BC051773(identity)|entrezgene/locuslink:23492(identity) refseq:NP_001001563.1|ensembl:ENSG00000105197(gene)|ensembl:ENST00000607714(transcript)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003723"(RNA binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005134"(interleukin-2 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007006"(mitochondrial membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR004274(NLI interacting factor)|interpro:IPR023214|interpro:IPR027111|interpro:IPR036412|mint:Q3ZCQ8|reactome:R-HSA-1268020|refseq:NP_001316488.1|dip:DIP-34058N|uniprotkb:Q3ZCQ8(identity)|entrezgene/locuslink:92609(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:LDXV9srMj1BL2CaSSot1Bn0/EW49606 rogid:fOPV33h12YhAq9jj0bVno01Q+6g9606 intact-crc:D5DA4700F11A7C29|rigid:HltlO5z8HGhhVHPnebe0ERkbqc4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95931 uniprotkb:P78364 intact:EBI-3923843|uniprotkb:Q86T17|ensembl:ENSP00000216133 intact:EBI-725403|uniprotkb:Q8WVM3|uniprotkb:Q9BU63|uniprotkb:D3DUV4|ensembl:ENSP00000437659|ensembl:ENSP00000440674 psi-mi:cbx7_human(display_long)|uniprotkb:CBX7(gene name)|psi-mi:CBX7(display_short) psi-mi:phc1_human(display_long)|uniprotkb:Early development regulatory protein 1(gene name synonym)|uniprotkb:PHC1(gene name)|psi-mi:PHC1(display_short)|uniprotkb:EDR1(gene name synonym)|uniprotkb:PH1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832106|imex:IM-21659-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783640.1|ensembl:ENSG00000100307(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|mint:O95931|rcsb pdb:2K1B|rcsb pdb:2L12|rcsb pdb:2L1B|rcsb pdb:3GS2|rcsb pdb:4MN3|rcsb pdb:5EPJ|rcsb pdb:6V2R|ensembl:ENST00000216133(transcript)|dip:DIP-44565N|uniprotkb:O95931(identity)|ddbj/embl/genbank:BC051773(identity)|entrezgene/locuslink:23492(identity) refseq:NP_004417.2|ensembl:ENSG00000111752(gene)|ensembl:ENST00000543824(transcript)|ensembl:ENST00000544916(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:P78364|rcsb pdb:2L8E|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|dip:DIP-44567N|uniprotkb:P78364(identity)|entrezgene/locuslink:1911(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:LDXV9srMj1BL2CaSSot1Bn0/EW49606 rogid:0dDjrgvWcP5Sx8h+qUj7awuM3ko9606 intact-crc:D5DA4700F11A7C29|rigid:HltlO5z8HGhhVHPnebe0ERkbqc4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95931 uniprotkb:Q8IXK0 intact:EBI-3923843|uniprotkb:Q86T17|ensembl:ENSP00000216133 intact:EBI-713786|uniprotkb:Q8N306|uniprotkb:Q8TAG8|uniprotkb:A1L4Q1|uniprotkb:Q2TAL3|uniprotkb:Q5T0C1|uniprotkb:Q6NUJ6|uniprotkb:Q6ZQR1|uniprotkb:Q96BL4|uniprotkb:Q9Y4Y7|ensembl:ENSP00000257118|uniprotkb:D3DPR2|uniprotkb:A8KA40 psi-mi:cbx7_human(display_long)|uniprotkb:CBX7(gene name)|psi-mi:CBX7(display_short) psi-mi:phc2_human(display_long)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:PHC2(gene name)|psi-mi:PHC2(display_short)|uniprotkb:EDR2(gene name synonym)|uniprotkb:PH2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832106|imex:IM-21659-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783640.1|ensembl:ENSG00000100307(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|mint:O95931|rcsb pdb:2K1B|rcsb pdb:2L12|rcsb pdb:2L1B|rcsb pdb:3GS2|rcsb pdb:4MN3|rcsb pdb:5EPJ|rcsb pdb:6V2R|ensembl:ENST00000216133(transcript)|dip:DIP-44565N|uniprotkb:O95931(identity)|ddbj/embl/genbank:BC051773(identity)|entrezgene/locuslink:23492(identity) interpro:IPR038603|mint:Q8IXK0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR013761(Sterile alpha motif-type)|ensembl:ENSG00000134686(gene)|ensembl:ENST00000257118(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|refseq:NP_004418.2|refseq:NP_932157.1|refseq:XP_016856005.1|refseq:XP_016856006.1|refseq:XP_016856007.1|refseq:XP_005270627.1|dip:DIP-34464N|uniprotkb:Q8IXK0(identity)|entrezgene/locuslink:1912(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:LDXV9srMj1BL2CaSSot1Bn0/EW49606 rogid:7si/KU2tHoxviuCr70ncQERDWmY9606 intact-crc:D5DA4700F11A7C29|rigid:HltlO5z8HGhhVHPnebe0ERkbqc4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95931 uniprotkb:P35226 intact:EBI-3923843|uniprotkb:Q86T17|ensembl:ENSP00000216133 intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851 psi-mi:cbx7_human(display_long)|uniprotkb:CBX7(gene name)|psi-mi:CBX7(display_short) psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832106|imex:IM-21659-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783640.1|ensembl:ENSG00000100307(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|mint:O95931|rcsb pdb:2K1B|rcsb pdb:2L12|rcsb pdb:2L1B|rcsb pdb:3GS2|rcsb pdb:4MN3|rcsb pdb:5EPJ|rcsb pdb:6V2R|ensembl:ENST00000216133(transcript)|dip:DIP-44565N|uniprotkb:O95931(identity)|ddbj/embl/genbank:BC051773(identity)|entrezgene/locuslink:23492(identity) refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:P35226(identity)|entrezgene/locuslink:100532731(identity)|entrezgene/locuslink:648(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:LDXV9srMj1BL2CaSSot1Bn0/EW49606 rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606 intact-crc:D5DA4700F11A7C29|rigid:HltlO5z8HGhhVHPnebe0ERkbqc4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HC52 uniprotkb:Q8NHM5 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 intact:EBI-3955564|uniprotkb:Q1RLM7|uniprotkb:Q8NCI2|uniprotkb:Q96HC7|uniprotkb:Q96SL0|uniprotkb:Q96T03|uniprotkb:Q9NS96|uniprotkb:Q9UF75|ensembl:ENSP00000366271|uniprotkb:A8MRS1 psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:kdm2b_human(display_long)|uniprotkb:KDM2B(gene name)|psi-mi:KDM2B(display_short)|uniprotkb:CXXC2(gene name synonym)|uniprotkb:FBL10(gene name synonym)|uniprotkb:FBXL10(gene name synonym)|uniprotkb:JHDM1B(gene name synonym)|uniprotkb:PCCX2(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 2(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 10(gene name synonym)|uniprotkb:F-box protein FBL10(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 10(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1B(gene name synonym)|uniprotkb:Jumonji domain-containing EMSY-interactor methyltransferase motif protein(gene name synonym)|uniprotkb:Protein-containing CXXC domain 2(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1B(gene name synonym)|uniprotkb:NDY1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832161|imex:IM-21659-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N|uniprotkb:Q9HC52(identity)|ddbj/embl/genbank:BC009376(identity)|entrezgene/locuslink:57332(identity) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENST00000377071(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0021555"(midbrain-hindbrain boundary morphogenesis)|go:"GO:0021592"(fourth ventricle development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021678"(third ventricle development)|go:"GO:0021993"(initiation of neural tube closure)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|interpro:IPR041070|interpro:IPR041667|mint:Q8NHM5|rcsb pdb:4O64|rcsb pdb:5JH5|rcsb pdb:6BVA|reactome:R-HSA-3214842|refseq:NP_115979.3|ensembl:ENSG00000089094(gene)|refseq:NP_001005366.1|uniprotkb:Q8NHM5(identity)|entrezgene/locuslink:84678(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rogid:tnMbfP2oxwaaDyHHAigNt5hx4hM9606 intact-crc:1BC40D35586C40F2|rigid:u3NpNhDDy9XCZ5HI36K+bglZkts false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HC52 uniprotkb:P61962 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832161|imex:IM-21659-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N|uniprotkb:Q9HC52(identity)|ddbj/embl/genbank:BC009376(identity)|entrezgene/locuslink:57332(identity) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 intact-crc:1BC40D35586C40F2|rigid:u3NpNhDDy9XCZ5HI36K+bglZkts false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HC52 uniprotkb:Q6W2J9 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832161|imex:IM-21659-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N|uniprotkb:Q9HC52(identity)|ddbj/embl/genbank:BC009376(identity)|entrezgene/locuslink:57332(identity) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N|uniprotkb:Q6W2J9(identity)|entrezgene/locuslink:54880(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 intact-crc:1BC40D35586C40F2|rigid:u3NpNhDDy9XCZ5HI36K+bglZkts false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HC52 uniprotkb:P63208 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832161|imex:IM-21659-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N|uniprotkb:Q9HC52(identity)|ddbj/embl/genbank:BC009376(identity)|entrezgene/locuslink:57332(identity) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|entrezgene/locuslink:6500(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 intact-crc:1BC40D35586C40F2|rigid:u3NpNhDDy9XCZ5HI36K+bglZkts false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HC52 uniprotkb:Q9HAH7 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 intact:EBI-2847800|uniprotkb:Q9H9X4|uniprotkb:Q96CI9|uniprotkb:B4DP86|ensembl:ENSP00000287468 psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:fbrs_human(display_long)|uniprotkb:FBRS(gene name)|psi-mi:FBRS(display_short)|uniprotkb:FBS(gene name synonym)|uniprotkb:FBS1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832161|imex:IM-21659-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N|uniprotkb:Q9HC52(identity)|ddbj/embl/genbank:BC009376(identity)|entrezgene/locuslink:57332(identity) refseq:NP_001098549.2|dip:DIP-61357N|ensembl:ENSG00000156860(gene)|ensembl:ENST00000287468(transcript)|interpro:IPR023246|mint:Q9HAH7|uniprotkb:Q9HAH7(identity)|entrezgene/locuslink:64319(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rogid:n1zkWAYdgwY+t7CFWg5RKO1VSfE9606 intact-crc:1BC40D35586C40F2|rigid:u3NpNhDDy9XCZ5HI36K+bglZkts false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HC52 uniprotkb:Q8IXK0 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 intact:EBI-713786|uniprotkb:Q8N306|uniprotkb:Q8TAG8|uniprotkb:A1L4Q1|uniprotkb:Q2TAL3|uniprotkb:Q5T0C1|uniprotkb:Q6NUJ6|uniprotkb:Q6ZQR1|uniprotkb:Q96BL4|uniprotkb:Q9Y4Y7|ensembl:ENSP00000257118|uniprotkb:D3DPR2|uniprotkb:A8KA40 psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:phc2_human(display_long)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:PHC2(gene name)|psi-mi:PHC2(display_short)|uniprotkb:EDR2(gene name synonym)|uniprotkb:PH2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832161|imex:IM-21659-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N|uniprotkb:Q9HC52(identity)|ddbj/embl/genbank:BC009376(identity)|entrezgene/locuslink:57332(identity) interpro:IPR038603|mint:Q8IXK0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR013761(Sterile alpha motif-type)|ensembl:ENSG00000134686(gene)|ensembl:ENST00000257118(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|refseq:NP_004418.2|refseq:NP_932157.1|refseq:XP_016856005.1|refseq:XP_016856006.1|refseq:XP_016856007.1|refseq:XP_005270627.1|dip:DIP-34464N|uniprotkb:Q8IXK0(identity)|entrezgene/locuslink:1912(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rogid:7si/KU2tHoxviuCr70ncQERDWmY9606 intact-crc:1BC40D35586C40F2|rigid:u3NpNhDDy9XCZ5HI36K+bglZkts false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HC52 uniprotkb:Q06587 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832161|imex:IM-21659-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N|uniprotkb:Q9HC52(identity)|ddbj/embl/genbank:BC009376(identity)|entrezgene/locuslink:57332(identity) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 intact-crc:1BC40D35586C40F2|rigid:u3NpNhDDy9XCZ5HI36K+bglZkts false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HC52 uniprotkb:Q99496 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832161|imex:IM-21659-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N|uniprotkb:Q9HC52(identity)|ddbj/embl/genbank:BC009376(identity)|entrezgene/locuslink:57332(identity) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|entrezgene/locuslink:6045(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 intact-crc:1BC40D35586C40F2|rigid:u3NpNhDDy9XCZ5HI36K+bglZkts false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HC52 uniprotkb:P35227 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 intact:EBI-2129767|uniprotkb:A6NGD8|ensembl:ENSP00000478517|ensembl:ENSP00000478970|ensembl:ENSP00000482063|ensembl:ENSP00000482815|ensembl:ENSP00000488868|ensembl:ENSP00000488872 psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:pcgf2_human(display_long)|uniprotkb:PCGF2(gene name)|psi-mi:PCGF2(display_short)|uniprotkb:MEL18(gene name synonym)|uniprotkb:RNF110(gene name synonym)|uniprotkb:ZNF144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832161|imex:IM-21659-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N|uniprotkb:Q9HC52(identity)|ddbj/embl/genbank:BC009376(identity)|entrezgene/locuslink:57332(identity) refseq:NP_009075.1|refseq:XP_016880505.1|refseq:XP_005257697.1|refseq:XP_005257698.1|refseq:XP_005257699.1|dip:DIP-41880N|ensembl:ENSG00000277258(gene)|ensembl:ENSG00000278644(gene)|ensembl:ENST00000610440(transcript)|ensembl:ENST00000611883(transcript)|ensembl:ENST00000616199(transcript)|ensembl:ENST00000620225(transcript)|ensembl:ENST00000631566(transcript)|ensembl:ENST00000631610(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35227|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-5617472|reactome:R-HSA-8953750|uniprotkb:P35227(identity)|entrezgene/locuslink:7703(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rogid:zppw56VrEl6gEFwtJMCN5cQkPxI9606 intact-crc:1BC40D35586C40F2|rigid:u3NpNhDDy9XCZ5HI36K+bglZkts false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HC52 uniprotkb:P35226 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851 psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832161|imex:IM-21659-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N|uniprotkb:Q9HC52(identity)|ddbj/embl/genbank:BC009376(identity)|entrezgene/locuslink:57332(identity) refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:P35226(identity)|entrezgene/locuslink:100532731(identity)|entrezgene/locuslink:648(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606 intact-crc:1BC40D35586C40F2|rigid:u3NpNhDDy9XCZ5HI36K+bglZkts false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HC52 uniprotkb:P78364 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 intact:EBI-725403|uniprotkb:Q8WVM3|uniprotkb:Q9BU63|uniprotkb:D3DUV4|ensembl:ENSP00000437659|ensembl:ENSP00000440674 psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:phc1_human(display_long)|uniprotkb:Early development regulatory protein 1(gene name synonym)|uniprotkb:PHC1(gene name)|psi-mi:PHC1(display_short)|uniprotkb:EDR1(gene name synonym)|uniprotkb:PH1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832161|imex:IM-21659-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N|uniprotkb:Q9HC52(identity)|ddbj/embl/genbank:BC009376(identity)|entrezgene/locuslink:57332(identity) refseq:NP_004417.2|ensembl:ENSG00000111752(gene)|ensembl:ENST00000543824(transcript)|ensembl:ENST00000544916(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:P78364|rcsb pdb:2L8E|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|dip:DIP-44567N|uniprotkb:P78364(identity)|entrezgene/locuslink:1911(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rogid:0dDjrgvWcP5Sx8h+qUj7awuM3ko9606 intact-crc:1BC40D35586C40F2|rigid:u3NpNhDDy9XCZ5HI36K+bglZkts false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HC52 uniprotkb:Q9BYE7 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832161|imex:IM-21659-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N|uniprotkb:Q9HC52(identity)|ddbj/embl/genbank:BC009376(identity)|entrezgene/locuslink:57332(identity) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 intact-crc:1BC40D35586C40F2|rigid:u3NpNhDDy9XCZ5HI36K+bglZkts false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HC52 uniprotkb:Q3KNV8 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 intact:EBI-2339807|uniprotkb:O15262|uniprotkb:D3DVN1|ensembl:ENSP00000354724|ensembl:ENSP00000420489 psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:pcgf3_human(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832161|imex:IM-21659-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N|uniprotkb:Q9HC52(identity)|ddbj/embl/genbank:BC009376(identity)|entrezgene/locuslink:57332(identity) refseq:NP_006306.2|refseq:NP_001304765.1|dip:DIP-52782N|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q3KNV8|uniprotkb:Q3KNV8(identity)|entrezgene/locuslink:10336(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606 intact-crc:1BC40D35586C40F2|rigid:u3NpNhDDy9XCZ5HI36K+bglZkts false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HC52 uniprotkb:Q9UN30 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 intact:EBI-6911404|ensembl:ENSP00000369380|uniprotkb:B2RA08|uniprotkb:Q5H969|uniprotkb:B0FZN6|uniprotkb:Q5H968 psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:scml1_human(display_long)|uniprotkb:SCML1(gene name)|psi-mi:SCML1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832161|imex:IM-21659-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N|uniprotkb:Q9HC52(identity)|ddbj/embl/genbank:BC009376(identity)|entrezgene/locuslink:57332(identity) ensembl:ENSG00000047634(gene)|ensembl:ENST00000380041(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q9UN30|refseq:XP_016885212.1|refseq:XP_006724571.1|refseq:NP_001032624.1|refseq:NP_001032625.1|refseq:NP_001032629.1|refseq:NP_006737.2|uniprotkb:Q9UN30(identity)|entrezgene/locuslink:6322(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rogid:/eJ/2Xuw4P5GzHy1wGRxnYZ4hvY9606 intact-crc:1BC40D35586C40F2|rigid:u3NpNhDDy9XCZ5HI36K+bglZkts false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HC52 uniprotkb:Q9BSM1 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832161|imex:IM-21659-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N|uniprotkb:Q9HC52(identity)|ddbj/embl/genbank:BC009376(identity)|entrezgene/locuslink:57332(identity) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5|uniprotkb:Q9BSM1(identity)|entrezgene/locuslink:84759(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 intact-crc:1BC40D35586C40F2|rigid:u3NpNhDDy9XCZ5HI36K+bglZkts false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HC52 uniprotkb:Q86SE9 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492 psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832161|imex:IM-21659-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N|uniprotkb:Q9HC52(identity)|ddbj/embl/genbank:BC009376(identity)|entrezgene/locuslink:57332(identity) refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N|uniprotkb:Q86SE9(identity)|entrezgene/locuslink:84333(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606 intact-crc:1BC40D35586C40F2|rigid:u3NpNhDDy9XCZ5HI36K+bglZkts false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HC52 uniprotkb:Q8NDX5 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 intact:EBI-1223801|uniprotkb:Q5HYF0|uniprotkb:Q6NSG2|uniprotkb:Q8NFT7|uniprotkb:Q8NFZ1|uniprotkb:Q8TBM2|uniprotkb:Q9H971|uniprotkb:Q9H9I4|uniprotkb:A2RRP9|ensembl:ENSP00000420271 psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:phc3_human(display_long)|uniprotkb:PHC3(gene name)|psi-mi:PHC3(display_short)|uniprotkb:EDR3(gene name synonym)|uniprotkb:PH3(gene name synonym)|uniprotkb:Homolog of polyhomeotic 3(gene name synonym)|uniprotkb:Early development regulatory protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832161|imex:IM-21659-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N|uniprotkb:Q9HC52(identity)|ddbj/embl/genbank:BC009376(identity)|entrezgene/locuslink:57332(identity) refseq:NP_079223.3|refseq:NP_001295045.1|ensembl:ENSP00000420271|ensembl:ENST00000495893|ensembl:ENSP00000420294|ensembl:ENST00000497658|ensembl:ENSP00000420454|ensembl:ENSG00000173889(gene)|ensembl:ENST00000494943(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:Q8NDX5|rcsb pdb:4PZN|rcsb pdb:4PZO|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q8NDX5(identity)|entrezgene/locuslink:80012(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rogid:hB1EMs+lCv19uuJ1O7+QiVCUoo89606 intact-crc:1BC40D35586C40F2|rigid:u3NpNhDDy9XCZ5HI36K+bglZkts false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68400 uniprotkb:Q06587 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832240|imex:IM-21659-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N|uniprotkb:P68400(identity)|ddbj/embl/genbank:BC011668(identity)|entrezgene/locuslink:1457(identity) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 intact-crc:EF2B2FB2B451C355|rigid:6F/vOTF+BkOQo9UL+LsH0CgsdTI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68400 uniprotkb:P67870 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 intact:EBI-348169|ensembl:ENSP00000365025|ensembl:ENSP00000365026|ensembl:ENSP00000365042|ensembl:ENSP00000372919|ensembl:ENSP00000372925|ensembl:ENSP00000382980|ensembl:ENSP00000390900|ensembl:ENSP00000391038|ensembl:ENSP00000393756|ensembl:ENSP00000394855|ensembl:ENSP00000395275|ensembl:ENSP00000400188|ensembl:ENSP00000407018|ensembl:ENSP00000407379|ensembl:ENSP00000409510|ensembl:ENSP00000410802|ensembl:ENSP00000411322|ensembl:ENSP00000412520|ensembl:ENSP00000413469|ensembl:ENSP00000415237|ensembl:ENSP00000415303|uniprotkb:P07312|uniprotkb:P13862|uniprotkb:Q4VX47|intact:EBI-3866975|uniprotkb:B0UXA9 psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:csk2b_human(display_long)|uniprotkb:Phosvitin(gene name synonym)|uniprotkb:Protein G5a(gene name synonym)|uniprotkb:CSNK2B(gene name)|psi-mi:CSNK2B(display_short)|uniprotkb:CK2N(gene name synonym)|uniprotkb:G5A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832240|imex:IM-21659-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N|uniprotkb:P68400(identity)|ddbj/embl/genbank:BC011668(identity)|entrezgene/locuslink:1457(identity) ensembl:ENSG00000204435(gene)|ensembl:ENSG00000230700(gene)|ensembl:ENSG00000206406(gene)|ensembl:ENSG00000232960(gene)|ensembl:ENSG00000224398(gene)|ensembl:ENSG00000224774(gene)|ensembl:ENSG00000228875(gene)|ensembl:ENST00000375882(transcript)|ensembl:ENST00000383427(transcript)|ensembl:ENST00000383433(transcript)|ensembl:ENST00000400110(transcript)|ensembl:ENST00000412802(transcript)|ensembl:ENST00000418230(transcript)|ensembl:ENST00000422567(transcript)|ensembl:ENST00000429633(transcript)|ensembl:ENST00000431476(transcript)|ensembl:ENST00000436169(transcript)|ensembl:ENST00000443673(transcript)|ensembl:ENST00000448596(transcript)|ensembl:ENST00000451917(transcript)|ensembl:ENST00000452985(transcript)|ensembl:ENST00000453234(transcript)|ensembl:ENST00000454382(transcript)|ensembl:ENST00000454511(transcript)|ensembl:ENST00000455161(transcript)|ensembl:ENST00000458330(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0007165"(signal transduction)|ensembl:ENST00000375865(transcript)|ensembl:ENST00000375866(transcript)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016363"(nuclear matrix)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0034622"|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|mint:P67870|rcsb pdb:1DS5|rcsb pdb:1JWH|go:"GO:0008134"(transcription factor binding)|rcsb pdb:1QF8|rcsb pdb:3EED|rcsb pdb:4DGL|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6798695|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:6Q38|refseq:NP_001311.3|refseq:NP_001269314.1|dip:DIP-131N|uniprotkb:P67870(identity)|entrezgene/locuslink:1460(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 rogid:ZTHJjCqHg2dE7B+WoSU28VSMuPg9606 intact-crc:EF2B2FB2B451C355|rigid:6F/vOTF+BkOQo9UL+LsH0CgsdTI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68400 uniprotkb:Q99496 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832240|imex:IM-21659-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N|uniprotkb:P68400(identity)|ddbj/embl/genbank:BC011668(identity)|entrezgene/locuslink:1457(identity) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|entrezgene/locuslink:6045(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 intact-crc:EF2B2FB2B451C355|rigid:6F/vOTF+BkOQo9UL+LsH0CgsdTI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68400 uniprotkb:Q15291 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 intact:EBI-592823|uniprotkb:A8K272|uniprotkb:Q7Z6D8|uniprotkb:Q8NDZ7|ensembl:ENSP00000264515 psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:rbbp5_human(display_long)|uniprotkb:Retinoblastoma-binding protein RBQ-3(gene name synonym)|uniprotkb:RBBP5(gene name)|psi-mi:RBBP5(display_short)|uniprotkb:RBQ3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832240|imex:IM-21659-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N|uniprotkb:P68400(identity)|ddbj/embl/genbank:BC011668(identity)|entrezgene/locuslink:1457(identity) refseq:NP_001180201.1|refseq:NP_001180202.1|refseq:NP_005048.2|dip:DIP-29224N|ensembl:ENSG00000117222(gene)|ensembl:ENST00000264515(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037850|mint:Q15291|rcsb pdb:3P4F|rcsb pdb:4X8N|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6KM7|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6PWX|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|uniprotkb:Q15291(identity)|entrezgene/locuslink:5929(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 rogid:Zl8yHcbL1C6StHPyD+875Ccy6gk9606 intact-crc:EF2B2FB2B451C355|rigid:6F/vOTF+BkOQo9UL+LsH0CgsdTI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68400 uniprotkb:Q3KNV8 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 intact:EBI-2339807|uniprotkb:O15262|uniprotkb:D3DVN1|ensembl:ENSP00000354724|ensembl:ENSP00000420489 psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:pcgf3_human(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832240|imex:IM-21659-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N|uniprotkb:P68400(identity)|ddbj/embl/genbank:BC011668(identity)|entrezgene/locuslink:1457(identity) refseq:NP_006306.2|refseq:NP_001304765.1|dip:DIP-52782N|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q3KNV8|uniprotkb:Q3KNV8(identity)|entrezgene/locuslink:10336(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606 intact-crc:EF2B2FB2B451C355|rigid:6F/vOTF+BkOQo9UL+LsH0CgsdTI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68400 uniprotkb:Q9HCM7 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 intact:EBI-6255777|ensembl:ENSP00000396160|uniprotkb:Q86XQ1 psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:fbsl_human(display_long)|uniprotkb:FBRSL1(gene name)|psi-mi:FBRSL1(display_short)|uniprotkb:AUTS2L(gene name synonym)|uniprotkb:KIAA1545(gene name synonym)|uniprotkb:XTP9(gene name synonym)|uniprotkb:AUTS2-like protein(gene name synonym)|uniprotkb:HBV X-transactivated gene 9 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832240|imex:IM-21659-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N|uniprotkb:P68400(identity)|ddbj/embl/genbank:BC011668(identity)|entrezgene/locuslink:1457(identity) ensembl:ENSG00000112787(gene)|ensembl:ENST00000434748(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR023246|refseq:NP_001136113.1|uniprotkb:Q9HCM7(identity)|entrezgene/locuslink:57666(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 rogid:JstP98Bp/L0+GmkLfSdhDHnWmiU9606 intact-crc:EF2B2FB2B451C355|rigid:6F/vOTF+BkOQo9UL+LsH0CgsdTI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68400 uniprotkb:Q8IY57 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832240|imex:IM-21659-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N|uniprotkb:P68400(identity)|ddbj/embl/genbank:BC011668(identity)|entrezgene/locuslink:1457(identity) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|entrezgene/locuslink:10138(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 intact-crc:EF2B2FB2B451C355|rigid:6F/vOTF+BkOQo9UL+LsH0CgsdTI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68400 uniprotkb:Q9C005 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 intact:EBI-744973|uniprotkb:D6W578|ensembl:ENSP00000295066|ensembl:ENSP00000345837 psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:dpy30_human(display_long)|uniprotkb:DPY30(gene name)|psi-mi:DPY30(display_short)|uniprotkb:Dpy-30-like protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832240|imex:IM-21659-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N|uniprotkb:P68400(identity)|ddbj/embl/genbank:BC011668(identity)|entrezgene/locuslink:1457(identity) refseq:NP_115963.1|ensembl:ENSG00000162961(gene)|ensembl:ENST00000295066(transcript)|ensembl:ENST00000342166(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006348"|go:"GO:0016197"(endosomal transport)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|mint:Q9C005|rcsb pdb:3G36|rcsb pdb:4RIQ|rcsb pdb:4RT4|rcsb pdb:4RTA|rcsb pdb:6E2H|rcsb pdb:6PWV|reactome:R-HSA-3214841|reactome:R-HSA-8936459|refseq:NP_001308138.1|dip:DIP-34476N|uniprotkb:Q9C005(identity)|entrezgene/locuslink:84661(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 rogid:yC9NJhTfEIT+YyfWRSJLGbRsQkc9606 intact-crc:EF2B2FB2B451C355|rigid:6F/vOTF+BkOQo9UL+LsH0CgsdTI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68400 uniprotkb:Q9HAH7 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 intact:EBI-2847800|uniprotkb:Q9H9X4|uniprotkb:Q96CI9|uniprotkb:B4DP86|ensembl:ENSP00000287468 psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:fbrs_human(display_long)|uniprotkb:FBRS(gene name)|psi-mi:FBRS(display_short)|uniprotkb:FBS(gene name synonym)|uniprotkb:FBS1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832240|imex:IM-21659-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N|uniprotkb:P68400(identity)|ddbj/embl/genbank:BC011668(identity)|entrezgene/locuslink:1457(identity) refseq:NP_001098549.2|dip:DIP-61357N|ensembl:ENSG00000156860(gene)|ensembl:ENST00000287468(transcript)|interpro:IPR023246|mint:Q9HAH7|uniprotkb:Q9HAH7(identity)|entrezgene/locuslink:64319(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 rogid:n1zkWAYdgwY+t7CFWg5RKO1VSfE9606 intact-crc:EF2B2FB2B451C355|rigid:6F/vOTF+BkOQo9UL+LsH0CgsdTI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68400 uniprotkb:Q8N488 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832240|imex:IM-21659-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N|uniprotkb:P68400(identity)|ddbj/embl/genbank:BC011668(identity)|entrezgene/locuslink:1457(identity) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|uniprotkb:Q8N488(identity)|entrezgene/locuslink:23429(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 intact-crc:EF2B2FB2B451C355|rigid:6F/vOTF+BkOQo9UL+LsH0CgsdTI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68400 uniprotkb:Q8WXX7 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 intact:EBI-2875359|ensembl:ENSP00000344087|uniprotkb:L7QET3|uniprotkb:L7QF75|uniprotkb:Q5D049|uniprotkb:Q9Y4F2|uniprotkb:A4D1Y9|uniprotkb:Q6PJU5 psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:auts2_human(display_long)|uniprotkb:AUTS2(gene name)|psi-mi:AUTS2(display_short)|uniprotkb:KIAA0442(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832240|imex:IM-21659-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N|uniprotkb:P68400(identity)|ddbj/embl/genbank:BC011668(identity)|entrezgene/locuslink:1457(identity) ensembl:ENSG00000158321(gene)|ensembl:ENST00000342771(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048675"(axon extension)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0097484"(dendrite extension)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR023246|reactome:R-HSA-8939243|refseq:NP_001120703.1|refseq:NP_001120704.1|refseq:NP_056385.1|dip:DIP-61355N|uniprotkb:Q8WXX7(identity)|entrezgene/locuslink:26053(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 rogid:8m3VWlXEISEyVwNmlwDFEEKl4Sg9606 intact-crc:EF2B2FB2B451C355|rigid:6F/vOTF+BkOQo9UL+LsH0CgsdTI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68400 uniprotkb:P61962 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832240|imex:IM-21659-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N|uniprotkb:P68400(identity)|ddbj/embl/genbank:BC011668(identity)|entrezgene/locuslink:1457(identity) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 intact-crc:EF2B2FB2B451C355|rigid:6F/vOTF+BkOQo9UL+LsH0CgsdTI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68400 uniprotkb:Q8TDD1 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 intact:EBI-1052503|uniprotkb:Q86YT8|uniprotkb:Q9BRZ1|ensembl:ENSP00000304072 psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:ddx54_human(display_long)|uniprotkb:DEAD box protein 54(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DP97(gene name synonym)|uniprotkb:DEAD box RNA helicase 97 kDa(gene name synonym)|uniprotkb:DDX54(gene name)|psi-mi:DDX54(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832240|imex:IM-21659-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N|uniprotkb:P68400(identity)|ddbj/embl/genbank:BC011668(identity)|entrezgene/locuslink:1457(identity) refseq:NP_001104792.1|refseq:NP_076977.3|ensembl:ENSG00000123064(gene)|ensembl:ENST00000306014(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012541(DBP10CT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR033517|mint:Q8TDD1|go:"GO:0003724"(RNA helicase activity)|uniprotkb:Q8TDD1(identity)|entrezgene/locuslink:79039(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 rogid:VzxEkRaOIND08jGJk3yyoztesjo9606 intact-crc:EF2B2FB2B451C355|rigid:6F/vOTF+BkOQo9UL+LsH0CgsdTI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68400 uniprotkb:P48643 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8 psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832240|imex:IM-21659-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N|uniprotkb:P68400(identity)|ddbj/embl/genbank:BC011668(identity)|entrezgene/locuslink:1457(identity) refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N|uniprotkb:P48643(identity)|entrezgene/locuslink:22948(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606 intact-crc:EF2B2FB2B451C355|rigid:6F/vOTF+BkOQo9UL+LsH0CgsdTI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68400 uniprotkb:Q86SE9 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492 psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832240|imex:IM-21659-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N|uniprotkb:P68400(identity)|ddbj/embl/genbank:BC011668(identity)|entrezgene/locuslink:1457(identity) refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N|uniprotkb:Q86SE9(identity)|entrezgene/locuslink:84333(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606 intact-crc:EF2B2FB2B451C355|rigid:6F/vOTF+BkOQo9UL+LsH0CgsdTI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68400 uniprotkb:Q03164 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 intact:EBI-591370|ensembl:ENSP00000374157|uniprotkb:Q13743|uniprotkb:Q13744|uniprotkb:Q14845|uniprotkb:Q16364|uniprotkb:Q6UBD1|uniprotkb:Q9UMA3|intact:EBI-2614650|uniprotkb:Q59FF2|uniprotkb:Q9UD94|uniprotkb:E9PQG7|uniprotkb:Q9HBJ3 psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:kmt2a_human(display_long)|uniprotkb:KMT2A(gene name)|psi-mi:KMT2A(display_short)|uniprotkb:ALL-1(gene name synonym)|uniprotkb:ALL1(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 7(gene name synonym)|uniprotkb:CXXC7(gene name synonym)|uniprotkb:HRX(gene name synonym)|uniprotkb:HTRX(gene name synonym)|uniprotkb:MLL(gene name synonym)|uniprotkb:MLL1(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 1(gene name synonym)|uniprotkb:TRX1(gene name synonym)|uniprotkb:Trithorax-like protein(gene name synonym)|uniprotkb:Zinc finger protein HRX(gene name synonym)|uniprotkb:Cysteine methyltransferase KMT2A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832240|imex:IM-21659-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N|uniprotkb:P68400(identity)|ddbj/embl/genbank:BC011668(identity)|entrezgene/locuslink:1457(identity) go:"GO:2000615"(regulation of histone H3-K9 acetylation)|interpro:IPR001214(SET)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036427|interpro:IPR037927|interpro:IPR041958|interpro:IPR042023|interpro:IPR042025|interpro:IPR044133|mint:Q03164|rcsb pdb:2AGH|rcsb pdb:2J2S|rcsb pdb:2JYI|rcsb pdb:2KKF|rcsb pdb:2KU7|rcsb pdb:2KYU|rcsb pdb:2LXS|rcsb pdb:2LXT|rcsb pdb:2MSR|rcsb pdb:2MTN|rcsb pdb:2W5Y|ensembl:ENSG00000118058(gene)|ensembl:ENST00000389506(transcript)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071440"(regulation of histone H3-K14 acetylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|go:"GO:1905642"(negative regulation of DNA methylation)|refseq:NP_001184033.1|refseq:NP_005924.2|ensembl:ENSP00000374157|ensembl:ENST00000534358|ensembl:ENSP00000436786|ensembl:ENST00000649699|ensembl:ENSP00000496927|dip:DIP-29221N|rcsb pdb:2W5Z|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3LQH|rcsb pdb:3LQI|rcsb pdb:3LQJ|rcsb pdb:3P4F|rcsb pdb:3U85|rcsb pdb:3U88|rcsb pdb:4ESG|rcsb pdb:4GQ6|rcsb pdb:4NW3|rcsb pdb:5F5E|rcsb pdb:5F6L|rcsb pdb:5SVH|rcsb pdb:6EMQ|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U9K|rcsb pdb:6U9M|rcsb pdb:6U9N|rcsb pdb:6U9R|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|reactome:R-HSA-3214841|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9616222|uniprotkb:Q03164(identity)|entrezgene/locuslink:4297(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 rogid:r9J9pjnLZI7GCBSHYqnmzjv9WvM9606 intact-crc:EF2B2FB2B451C355|rigid:6F/vOTF+BkOQo9UL+LsH0CgsdTI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68400 uniprotkb:O75683 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 intact:EBI-2691252|uniprotkb:Q9UK24|uniprotkb:Q9BTZ5|uniprotkb:Q5T8U1|uniprotkb:Q9BRK9|ensembl:ENSP00000361092|ensembl:ENSP00000485909 psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:surf6_human(display_long)|uniprotkb:SURF-6(gene name synonym)|uniprotkb:SURF6(gene name)|psi-mi:SURF6(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832240|imex:IM-21659-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N|uniprotkb:P68400(identity)|ddbj/embl/genbank:BC011668(identity)|entrezgene/locuslink:1457(identity) refseq:NP_006744.2|refseq:NP_001265871.1|ensembl:ENSG00000148296(gene)|ensembl:ENSG00000281309(gene)|ensembl:ENST00000372022(transcript)|ensembl:ENST00000629980(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR007019(Surfeit locus 6)|interpro:IPR029190|uniprotkb:O75683(identity)|entrezgene/locuslink:6838(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 rogid:1Yzf0+p31xuzJXSoaiz9THfjF0c9606 intact-crc:EF2B2FB2B451C355|rigid:6F/vOTF+BkOQo9UL+LsH0CgsdTI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68400 uniprotkb:Q9UMN6 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 intact:EBI-765774|uniprotkb:O15022|uniprotkb:O95836|uniprotkb:Q96GP2|uniprotkb:Q96IP3|uniprotkb:Q9UK25|uniprotkb:Q9Y668|uniprotkb:Q9Y669|ensembl:ENSP00000398837 psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:kmt2b_human(display_long)|uniprotkb:KMT2B(gene name)|psi-mi:KMT2B(display_short)|uniprotkb:HRX2(gene name synonym)|uniprotkb:KIAA0304(gene name synonym)|uniprotkb:MLL2(gene name synonym)|uniprotkb:MLL4(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 4(gene name synonym)|uniprotkb:TRX2(gene name synonym)|uniprotkb:Trithorax homolog 2(gene name synonym)|uniprotkb:WBP7(gene name synonym)|uniprotkb:WW domain-binding protein 7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832240|imex:IM-21659-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N|uniprotkb:P68400(identity)|ddbj/embl/genbank:BC011668(identity)|entrezgene/locuslink:1457(identity) ensembl:ENSP00000398837|dip:DIP-34598N|ensembl:ENSG00000272333(gene)|ensembl:ENST00000420124(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR001214(SET)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036427|interpro:IPR041959|mint:Q9UMN6|rcsb pdb:3UVM|rcsb pdb:4ERZ|rcsb pdb:4PZI|rcsb pdb:7BRE|reactome:R-HSA-3214841|reactome:R-HSA-8936459|uniprotkb:Q9UMN6(identity)|entrezgene/locuslink:9757(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 rogid:1Im1Dqkyg85ZGqrxLaK4wyMVGNY9606 intact-crc:EF2B2FB2B451C355|rigid:6F/vOTF+BkOQo9UL+LsH0CgsdTI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68400 uniprotkb:P19784 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 intact:EBI-347451|ensembl:ENSP00000262506 psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832240|imex:IM-21659-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N|uniprotkb:P68400(identity)|ddbj/embl/genbank:BC011668(identity)|entrezgene/locuslink:1457(identity) refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|uniprotkb:P19784(identity)|entrezgene/locuslink:1459(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 intact-crc:EF2B2FB2B451C355|rigid:6F/vOTF+BkOQo9UL+LsH0CgsdTI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68400 uniprotkb:Q9NZM5 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 intact:EBI-720156|uniprotkb:Q9BTC6|uniprotkb:Q9HAX6|uniprotkb:Q9NPP1|uniprotkb:Q9NPR4|uniprotkb:Q9UFI2|ensembl:ENSP00000246802 psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:nop53_human(display_long)|uniprotkb:NOP53(gene name)|psi-mi:NOP53(display_short)|uniprotkb:GLT(gene name synonym)|uniprotkb:GLTSCR2(gene name synonym)|uniprotkb:Glioma tumor suppressor candidate region gene 2 protein(gene name synonym)|uniprotkb:PICT1(gene name synonym)|uniprotkb:Protein interacting with carboxyl terminus 1(gene name synonym)|uniprotkb:p60(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832240|imex:IM-21659-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N|uniprotkb:P68400(identity)|ddbj/embl/genbank:BC011668(identity)|entrezgene/locuslink:1457(identity) refseq:NP_056525.2|ensembl:ENSG00000105373(gene)|ensembl:ENST00000246802(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006364"(rRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0039535"(regulation of RIG-I signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0003723"(RNA binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1901797"(negative regulation of signal transduction by p53 class mediator)|go:"GO:1901837"(negative regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902570"(protein localization to nucleolus)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1990173"(protein localization to nucleoplasm)|interpro:IPR011687(P60-like)|mint:Q9NZM5|go:"GO:0050821"(protein stabilization)|uniprotkb:Q9NZM5(identity)|entrezgene/locuslink:29997(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 rogid:64EYf68f9eP9SfPBJhjbxuJcn2g9606 intact-crc:EF2B2FB2B451C355|rigid:6F/vOTF+BkOQo9UL+LsH0CgsdTI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68400 uniprotkb:Q9BYG3 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 intact:EBI-2561019|ensembl:ENSP00000285814|uniprotkb:Q8TB66|uniprotkb:A8K788|uniprotkb:Q96ED4 psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:mk67i_human(display_long)|uniprotkb:NIFK(gene name)|psi-mi:NIFK(display_short)|uniprotkb:MKI67IP(gene name synonym)|uniprotkb:NOPP34(gene name synonym)|uniprotkb:Nucleolar phosphoprotein Nopp34(gene name synonym)|uniprotkb:Nucleolar protein interacting with the FHA domain of pKI-67(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832240|imex:IM-21659-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N|uniprotkb:P68400(identity)|ddbj/embl/genbank:BC011668(identity)|entrezgene/locuslink:1457(identity) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009303"(rRNA transcription)|go:"GO:0016072"(rRNA metabolic process)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021043|interpro:IPR035979|mint:Q9BYG3|rcsb pdb:2AFF|ensembl:ENSG00000155438(gene)|ensembl:ENST00000285814(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000794"(condensed nuclear chromosome)|refseq:NP_115766.3|dip:DIP-28134N|uniprotkb:Q9BYG3(identity)|entrezgene/locuslink:84365(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 rogid:DUc8AnzFxJjbK+cTW5H83GQcf6o9606 intact-crc:EF2B2FB2B451C355|rigid:6F/vOTF+BkOQo9UL+LsH0CgsdTI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68400 uniprotkb:P61964 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832240|imex:IM-21659-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N|uniprotkb:P68400(identity)|ddbj/embl/genbank:BC011668(identity)|entrezgene/locuslink:1457(identity) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|entrezgene/locuslink:11091(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 intact-crc:EF2B2FB2B451C355|rigid:6F/vOTF+BkOQo9UL+LsH0CgsdTI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61962 uniprotkb:Q3KNV8 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 intact:EBI-2339807|uniprotkb:O15262|uniprotkb:D3DVN1|ensembl:ENSP00000354724|ensembl:ENSP00000420489 psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:pcgf3_human(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832455|imex:IM-21659-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity)|ddbj/embl/genbank:BC001264(identity) refseq:NP_006306.2|refseq:NP_001304765.1|dip:DIP-52782N|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q3KNV8|uniprotkb:Q3KNV8(identity)|entrezgene/locuslink:10336(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606 intact-crc:91C53749B744D275|rigid:r8kOLkaJcNciWCnVNH0aNrs+sIc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61962 uniprotkb:P19784 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 intact:EBI-347451|ensembl:ENSP00000262506 psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832455|imex:IM-21659-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity)|ddbj/embl/genbank:BC001264(identity) refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|uniprotkb:P19784(identity)|entrezgene/locuslink:1459(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 intact-crc:91C53749B744D275|rigid:r8kOLkaJcNciWCnVNH0aNrs+sIc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61962 uniprotkb:P67870 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 intact:EBI-348169|ensembl:ENSP00000365025|ensembl:ENSP00000365026|ensembl:ENSP00000365042|ensembl:ENSP00000372919|ensembl:ENSP00000372925|ensembl:ENSP00000382980|ensembl:ENSP00000390900|ensembl:ENSP00000391038|ensembl:ENSP00000393756|ensembl:ENSP00000394855|ensembl:ENSP00000395275|ensembl:ENSP00000400188|ensembl:ENSP00000407018|ensembl:ENSP00000407379|ensembl:ENSP00000409510|ensembl:ENSP00000410802|ensembl:ENSP00000411322|ensembl:ENSP00000412520|ensembl:ENSP00000413469|ensembl:ENSP00000415237|ensembl:ENSP00000415303|uniprotkb:P07312|uniprotkb:P13862|uniprotkb:Q4VX47|intact:EBI-3866975|uniprotkb:B0UXA9 psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:csk2b_human(display_long)|uniprotkb:Phosvitin(gene name synonym)|uniprotkb:Protein G5a(gene name synonym)|uniprotkb:CSNK2B(gene name)|psi-mi:CSNK2B(display_short)|uniprotkb:CK2N(gene name synonym)|uniprotkb:G5A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832455|imex:IM-21659-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity)|ddbj/embl/genbank:BC001264(identity) ensembl:ENSG00000204435(gene)|ensembl:ENSG00000230700(gene)|ensembl:ENSG00000206406(gene)|ensembl:ENSG00000232960(gene)|ensembl:ENSG00000224398(gene)|ensembl:ENSG00000224774(gene)|ensembl:ENSG00000228875(gene)|ensembl:ENST00000375882(transcript)|ensembl:ENST00000383427(transcript)|ensembl:ENST00000383433(transcript)|ensembl:ENST00000400110(transcript)|ensembl:ENST00000412802(transcript)|ensembl:ENST00000418230(transcript)|ensembl:ENST00000422567(transcript)|ensembl:ENST00000429633(transcript)|ensembl:ENST00000431476(transcript)|ensembl:ENST00000436169(transcript)|ensembl:ENST00000443673(transcript)|ensembl:ENST00000448596(transcript)|ensembl:ENST00000451917(transcript)|ensembl:ENST00000452985(transcript)|ensembl:ENST00000453234(transcript)|ensembl:ENST00000454382(transcript)|ensembl:ENST00000454511(transcript)|ensembl:ENST00000455161(transcript)|ensembl:ENST00000458330(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0007165"(signal transduction)|ensembl:ENST00000375865(transcript)|ensembl:ENST00000375866(transcript)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016363"(nuclear matrix)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0034622"|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|mint:P67870|rcsb pdb:1DS5|rcsb pdb:1JWH|go:"GO:0008134"(transcription factor binding)|rcsb pdb:1QF8|rcsb pdb:3EED|rcsb pdb:4DGL|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6798695|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:6Q38|refseq:NP_001311.3|refseq:NP_001269314.1|dip:DIP-131N|uniprotkb:P67870(identity)|entrezgene/locuslink:1460(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rogid:ZTHJjCqHg2dE7B+WoSU28VSMuPg9606 intact-crc:91C53749B744D275|rigid:r8kOLkaJcNciWCnVNH0aNrs+sIc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61962 uniprotkb:Q9Y463 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 intact:EBI-634187|uniprotkb:O75258|uniprotkb:O75788|uniprotkb:O75789|ensembl:ENSP00000312789|ensembl:ENSP00000469863|ensembl:ENSP00000485915|ensembl:ENSP00000486377 psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:dyr1b_human(display_long)|uniprotkb:Mirk protein kinase(gene name synonym)|uniprotkb:Minibrain-related kinase(gene name synonym)|uniprotkb:DYRK1B(gene name)|psi-mi:DYRK1B(display_short)|uniprotkb:MIRK(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832455|imex:IM-21659-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity)|ddbj/embl/genbank:BC001264(identity) refseq:NP_004705.1|refseq:NP_006474.1|refseq:NP_006475.1|refseq:XP_005259455.1|ensembl:ENSG00000105204(gene)|ensembl:ENSG00000281320(gene)|ensembl:ENST00000323039(transcript)|ensembl:ENST00000593685(transcript)|ensembl:ENST00000625757(transcript)|ensembl:ENST00000631090(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007520"(myoblast fusion)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060612"(adipose tissue development)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028318|interpro:IPR044131|mint:Q9Y463|go:"GO:0106310"(protein serine kinase activity)|uniprotkb:Q9Y463(identity)|entrezgene/locuslink:9149(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rogid:MaG/ZUw0KMo5JxQdeIhMu0DebXI9606 intact-crc:91C53749B744D275|rigid:r8kOLkaJcNciWCnVNH0aNrs+sIc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61962 uniprotkb:Q92526 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 intact:EBI-2479962|ensembl:ENSP00000327191|uniprotkb:Q8TC34|uniprotkb:B4DYB0|uniprotkb:B4DX20 psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:tcpw_human(display_long)|uniprotkb:CCT6B(gene name)|psi-mi:CCT6B(display_short)|uniprotkb:CCT-zeta-2(gene name synonym)|uniprotkb:TCP-1-zeta-like(gene name synonym)|uniprotkb:CCT-zeta-like(gene name synonym)|uniprotkb:Testis-specific Tcp20(gene name synonym)|uniprotkb:Testis-specific protein TSA303(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832455|imex:IM-21659-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity)|ddbj/embl/genbank:BC001264(identity) interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|ensembl:ENSG00000132141(gene)|ensembl:ENST00000314144(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0006457"(protein folding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1901998"(toxin transport)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|refseq:NP_001180458.1|refseq:NP_001180459.1|refseq:NP_006575.2|dip:DIP-53269N|uniprotkb:Q92526(identity)|entrezgene/locuslink:10693(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rogid:VsftnWywz8pwjvqMpE33d9z3bY09606 intact-crc:91C53749B744D275|rigid:r8kOLkaJcNciWCnVNH0aNrs+sIc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61962 uniprotkb:Q86SE9 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492 psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832455|imex:IM-21659-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity)|ddbj/embl/genbank:BC001264(identity) refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N|uniprotkb:Q86SE9(identity)|entrezgene/locuslink:84333(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606 intact-crc:91C53749B744D275|rigid:r8kOLkaJcNciWCnVNH0aNrs+sIc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61962 uniprotkb:Q06587 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832455|imex:IM-21659-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity)|ddbj/embl/genbank:BC001264(identity) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 intact-crc:91C53749B744D275|rigid:r8kOLkaJcNciWCnVNH0aNrs+sIc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61962 uniprotkb:P68400 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832455|imex:IM-21659-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity)|ddbj/embl/genbank:BC001264(identity) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N|uniprotkb:P68400(identity)|entrezgene/locuslink:1457(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 intact-crc:91C53749B744D275|rigid:r8kOLkaJcNciWCnVNH0aNrs+sIc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61962 uniprotkb:Q13627 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 intact:EBI-1053596|uniprotkb:O60769|uniprotkb:Q92582|uniprotkb:Q92810|uniprotkb:Q9UNM5|ensembl:ENSP00000381932|ensembl:ENSP00000494544 psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:dyr1a_human(display_long)|uniprotkb:Protein kinase minibrain homolog(gene name synonym)|uniprotkb:HP86(gene name synonym)|uniprotkb:Dual specificity YAK1-related kinase(gene name synonym)|uniprotkb:DYRK1A(gene name)|psi-mi:DYRK1A(display_short)|uniprotkb:DYRK(gene name synonym)|uniprotkb:MNB(gene name synonym)|uniprotkb:MNBH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832455|imex:IM-21659-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity)|ddbj/embl/genbank:BC001264(identity) refseq:NP_001387.2|refseq:NP_567824.1|refseq:NP_569120.1|refseq:NP_569122.1|refseq:XP_011527785.1|refseq:XP_006724039.1|refseq:XP_006724040.1|refseq:XP_006724041.1|ensembl:ENSG00000157540(gene)|ensembl:ENST00000398960(transcript)|ensembl:ENST00000644942(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003779"(actin binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007399"(nervous system development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031115"(negative regulation of microtubule polymerization)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034205"(amyloid-beta formation)|go:"GO:0036289"(peptidyl-serine autophosphorylation)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043621"(protein self-association)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048156"(tau protein binding)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028318|interpro:IPR044131|mint:Q13627|rcsb pdb:2VX3|rcsb pdb:2WO6|rcsb pdb:3ANQ|rcsb pdb:3ANR|rcsb pdb:4AZE|rcsb pdb:4MQ1|rcsb pdb:4MQ2|rcsb pdb:4NCT|rcsb pdb:4YLJ|rcsb pdb:4YLK|rcsb pdb:4YLL|rcsb pdb:4YU2|rcsb pdb:5A3X|rcsb pdb:5A4E|rcsb pdb:5A4L|rcsb pdb:5A4Q|rcsb pdb:5A4T|rcsb pdb:5A54|rcsb pdb:5AIK|rcsb pdb:6A1G|rcsb pdb:6EIF|rcsb pdb:6EIJ|rcsb pdb:6EIL|rcsb pdb:6EIP|rcsb pdb:6EIQ|rcsb pdb:6EIR|rcsb pdb:6EIS|rcsb pdb:6EIV|rcsb pdb:6EJ4|rcsb pdb:6QU2|rcsb pdb:6S11|rcsb pdb:6S14|rcsb pdb:6S17|rcsb pdb:6S1B|rcsb pdb:6S1H|rcsb pdb:6S1I|rcsb pdb:6S1J|rcsb pdb:6T6A|rcsb pdb:6UIP|rcsb pdb:6UWY|rcsb pdb:6YF8|rcsb pdb:7A4O|rcsb pdb:7A4R|rcsb pdb:7A4S|rcsb pdb:7A4W|rcsb pdb:7A4Z|rcsb pdb:7A51|rcsb pdb:7A52|rcsb pdb:7A53|rcsb pdb:7A55|rcsb pdb:7A5B|rcsb pdb:7A5D|rcsb pdb:7A5L|rcsb pdb:7A5N|rcsb pdb:7AJ2|rcsb pdb:7AJ4|rcsb pdb:7AJ5|rcsb pdb:7AJ7|rcsb pdb:7AJ8|rcsb pdb:7AJA|rcsb pdb:7AJM|rcsb pdb:7AJS|rcsb pdb:7AJV|rcsb pdb:7AJW|rcsb pdb:7AJY|rcsb pdb:7AK2|rcsb pdb:7AKA|rcsb pdb:7AKB|rcsb pdb:7AKE|rcsb pdb:7AKL|reactome:R-HSA-1538133|rcsb pdb:6A1F|refseq:XP_016883773.1|refseq:NP_001334650.1|refseq:NP_001334651.1|dip:DIP-39750N|uniprotkb:Q13627(identity)|entrezgene/locuslink:1859(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rogid:1Y5lOF9SszLsUVauAnydhzUh7fM9606 intact-crc:91C53749B744D275|rigid:r8kOLkaJcNciWCnVNH0aNrs+sIc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61962 uniprotkb:P17987 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334 psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832455|imex:IM-21659-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity)|ddbj/embl/genbank:BC001264(identity) refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N|uniprotkb:P17987(identity)|entrezgene/locuslink:6950(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606 intact-crc:91C53749B744D275|rigid:r8kOLkaJcNciWCnVNH0aNrs+sIc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61962 uniprotkb:Q12815 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 intact:EBI-2349743|uniprotkb:Q8N5B2|uniprotkb:F8VSF9|uniprotkb:Q6PJU7|ensembl:ENSP00000257909 psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:troap_human(display_long)|uniprotkb:TROAP(gene name)|psi-mi:TROAP(display_short)|uniprotkb:Trophinin-assisting protein(gene name synonym)|uniprotkb:Trophinin-associated protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832455|imex:IM-21659-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity)|ddbj/embl/genbank:BC001264(identity) refseq:XP_011536027.1|refseq:NP_001094090.1|refseq:NP_005471.3|refseq:NP_001265253.1|dip:DIP-52951N|ensembl:ENSG00000135451(gene)|ensembl:ENST00000257909(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007155"(cell adhesion)|interpro:IPR026133|mint:Q12815|uniprotkb:Q12815(identity)|entrezgene/locuslink:10024(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rogid:9+3f9EdjzudEOEIYnDMmZGrjjKA9606 intact-crc:91C53749B744D275|rigid:r8kOLkaJcNciWCnVNH0aNrs+sIc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61962 uniprotkb:Q99471 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 intact:EBI-357275|ensembl:ENSP00000334188|ensembl:ENSP00000447942|intact:EBI-1047551|uniprotkb:A8K9A8|uniprotkb:Q54AA8|uniprotkb:Q9C083|uniprotkb:Q9C084 psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:pfd5_human(display_long)|uniprotkb:c-Myc-binding protein Mm-1(gene name synonym)|uniprotkb:PFDN5(gene name)|psi-mi:PFDN5(display_short)|uniprotkb:MM1(gene name synonym)|uniprotkb:Myc modulator 1(gene name synonym)|uniprotkb:PFD5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832455|imex:IM-21659-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity)|ddbj/embl/genbank:BC001264(identity) ensembl:ENSG00000123349(gene)|ensembl:ENST00000334478(transcript)|ensembl:ENST00000551018(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR011599(Prefoldin alpha subunit)|mint:Q99471|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957|refseq:NP_002615.2|refseq:NP_665904.1|dip:DIP-28155N|uniprotkb:Q99471(identity)|entrezgene/locuslink:5204(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rogid:Cm4km207qcfDJYRUCIwUxMBT4tE9606 intact-crc:91C53749B744D275|rigid:r8kOLkaJcNciWCnVNH0aNrs+sIc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61962 uniprotkb:P40227 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2 psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832455|imex:IM-21659-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity)|ddbj/embl/genbank:BC001264(identity) refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N|uniprotkb:P40227(identity)|entrezgene/locuslink:908(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606 intact-crc:91C53749B744D275|rigid:r8kOLkaJcNciWCnVNH0aNrs+sIc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61962 uniprotkb:Q8IY57 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832455|imex:IM-21659-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity)|ddbj/embl/genbank:BC001264(identity) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|entrezgene/locuslink:10138(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 intact-crc:91C53749B744D275|rigid:r8kOLkaJcNciWCnVNH0aNrs+sIc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61962 uniprotkb:Q9NQP4 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 intact:EBI-357021|uniprotkb:Q5TD11|uniprotkb:Q92779|ensembl:ENSP00000360473 psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:pfd4_human(display_long)|uniprotkb:PFDN4(gene name)|psi-mi:PFDN4(display_short)|uniprotkb:PFD4(gene name synonym)|uniprotkb:Protein C-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832455|imex:IM-21659-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity)|ddbj/embl/genbank:BC001264(identity) refseq:NP_002614.2|ensembl:ENSG00000101132(gene)|ensembl:ENST00000371419(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|interpro:IPR016661(Prefoldin, subunit 4)|mint:Q9NQP4|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957|uniprotkb:Q9NQP4(identity)|entrezgene/locuslink:5203(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rogid:oXbJiHxqcYHrAWGGgzV81ocGt889606 intact-crc:91C53749B744D275|rigid:r8kOLkaJcNciWCnVNH0aNrs+sIc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61962 uniprotkb:Q9NYF3 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 intact:EBI-1644252|uniprotkb:D3DQB9|uniprotkb:B2RDJ5|ensembl:ENSP00000239906|ensembl:ENSP00000403705 psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:fa53c_human(display_long)|uniprotkb:FAM53C(gene name)|psi-mi:FAM53C(display_short)|uniprotkb:C5orf6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832455|imex:IM-21659-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity)|ddbj/embl/genbank:BC001264(identity) refseq:NP_001129119.1|refseq:NP_057689.1|ensembl:ENSG00000120709(gene)|ensembl:ENST00000239906(transcript)|ensembl:ENST00000434981(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006606"(protein import into nucleus)|interpro:IPR029356|uniprotkb:Q9NYF3(identity)|entrezgene/locuslink:51307(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rogid:DOnDTyw+f+NYBQnR1iWWlajGf9I9606 intact-crc:91C53749B744D275|rigid:r8kOLkaJcNciWCnVNH0aNrs+sIc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61962 uniprotkb:Q2M3V2 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 intact:EBI-8832444|uniprotkb:Q8NAE7|ensembl:ENSP00000367965 psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:swaha_human(display_long)|uniprotkb:ANKRD43(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 43(gene name synonym)|uniprotkb:Protein sosondowah homolog A(gene name synonym)|uniprotkb:SOWAHA(gene name)|psi-mi:SOWAHA(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832455|imex:IM-21659-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity)|ddbj/embl/genbank:BC001264(identity) interpro:IPR020683|interpro:IPR036770|interpro:IPR002110(Ankyrin)|ensembl:ENSG00000198944(gene)|ensembl:ENST00000378693(transcript)|uniprotkb:Q2M3V2(identity)|entrezgene/locuslink:134548(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rogid:g+0UUHyTBCPargErdMKbnW/TzHY9606 intact-crc:91C53749B744D275|rigid:r8kOLkaJcNciWCnVNH0aNrs+sIc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61962 uniprotkb:Q99496 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832455|imex:IM-21659-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity)|ddbj/embl/genbank:BC001264(identity) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|entrezgene/locuslink:6045(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 intact-crc:91C53749B744D275|rigid:r8kOLkaJcNciWCnVNH0aNrs+sIc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61962 uniprotkb:P50991 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958 psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832455|imex:IM-21659-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity)|ddbj/embl/genbank:BC001264(identity) refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998|uniprotkb:P50991(identity)|entrezgene/locuslink:10575(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606 intact-crc:91C53749B744D275|rigid:r8kOLkaJcNciWCnVNH0aNrs+sIc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61962 uniprotkb:P49368 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688 psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832455|imex:IM-21659-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity)|ddbj/embl/genbank:BC001264(identity) refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N|uniprotkb:P49368(identity)|entrezgene/locuslink:7203(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606 intact-crc:91C53749B744D275|rigid:r8kOLkaJcNciWCnVNH0aNrs+sIc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61962 uniprotkb:P48643 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8 psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832455|imex:IM-21659-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity)|ddbj/embl/genbank:BC001264(identity) refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N|uniprotkb:P48643(identity)|entrezgene/locuslink:22948(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606 intact-crc:91C53749B744D275|rigid:r8kOLkaJcNciWCnVNH0aNrs+sIc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61962 uniprotkb:Q96F45 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 intact:EBI-8832437|uniprotkb:Q96E25|uniprotkb:Q8NAC5|uniprotkb:Q96IJ0|ensembl:ENSP00000361602 psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:zn503_human(display_long)|uniprotkb:NOLZ1(gene name synonym)|uniprotkb:ZNF503(gene name)|psi-mi:ZNF503(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832455|imex:IM-21659-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity)|ddbj/embl/genbank:BC001264(identity) refseq:NP_116161.2|ensembl:ENSG00000165655(gene)|ensembl:ENST00000372524(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0070315"(G1 to G0 transition involved in cell differentiation)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022129|uniprotkb:Q96F45(identity)|entrezgene/locuslink:84858(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rogid:NpN+RnNBhDISreteXZIxozWoURI9606 intact-crc:91C53749B744D275|rigid:r8kOLkaJcNciWCnVNH0aNrs+sIc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61962 uniprotkb:P78371 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300 psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832455|imex:IM-21659-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity)|ddbj/embl/genbank:BC001264(identity) refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695|uniprotkb:P78371(identity)|entrezgene/locuslink:10576(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606 intact-crc:91C53749B744D275|rigid:r8kOLkaJcNciWCnVNH0aNrs+sIc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61962 uniprotkb:Q8WXX7 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 intact:EBI-2875359|ensembl:ENSP00000344087|uniprotkb:L7QET3|uniprotkb:L7QF75|uniprotkb:Q5D049|uniprotkb:Q9Y4F2|uniprotkb:A4D1Y9|uniprotkb:Q6PJU5 psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:auts2_human(display_long)|uniprotkb:AUTS2(gene name)|psi-mi:AUTS2(display_short)|uniprotkb:KIAA0442(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832455|imex:IM-21659-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity)|ddbj/embl/genbank:BC001264(identity) ensembl:ENSG00000158321(gene)|ensembl:ENST00000342771(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048675"(axon extension)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0097484"(dendrite extension)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR023246|reactome:R-HSA-8939243|refseq:NP_001120703.1|refseq:NP_001120704.1|refseq:NP_056385.1|dip:DIP-61355N|uniprotkb:Q8WXX7(identity)|entrezgene/locuslink:26053(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rogid:8m3VWlXEISEyVwNmlwDFEEKl4Sg9606 intact-crc:91C53749B744D275|rigid:r8kOLkaJcNciWCnVNH0aNrs+sIc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61962 uniprotkb:Q9H7S9 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 intact:EBI-3957070|uniprotkb:Q5XG76|ensembl:ENSP00000332325 psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:zn703_human(display_long)|uniprotkb:ZNF703(gene name)|psi-mi:ZNF703(display_short)|uniprotkb:ZEPPO1(gene name synonym)|uniprotkb:ZPO1(gene name synonym)|uniprotkb:Zinc finger elbow-related proline domain protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832455|imex:IM-21659-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity)|ddbj/embl/genbank:BC001264(identity) ensembl:ENSG00000183779(gene)|ensembl:ENST00000331569(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034111"(negative regulation of homotypic cell-cell adhesion)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022129|reactome:R-HSA-212436|refseq:NP_079345.1|uniprotkb:Q9H7S9(identity)|entrezgene/locuslink:80139(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rogid:6o2BN2iquHZVAhS8rqsdMIJrZ0A9606 intact-crc:91C53749B744D275|rigid:r8kOLkaJcNciWCnVNH0aNrs+sIc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61962 uniprotkb:Q9HAH7 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 intact:EBI-2847800|uniprotkb:Q9H9X4|uniprotkb:Q96CI9|uniprotkb:B4DP86|ensembl:ENSP00000287468 psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:fbrs_human(display_long)|uniprotkb:FBRS(gene name)|psi-mi:FBRS(display_short)|uniprotkb:FBS(gene name synonym)|uniprotkb:FBS1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832455|imex:IM-21659-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity)|ddbj/embl/genbank:BC001264(identity) refseq:NP_001098549.2|dip:DIP-61357N|ensembl:ENSG00000156860(gene)|ensembl:ENST00000287468(transcript)|interpro:IPR023246|mint:Q9HAH7|uniprotkb:Q9HAH7(identity)|entrezgene/locuslink:64319(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rogid:n1zkWAYdgwY+t7CFWg5RKO1VSfE9606 intact-crc:91C53749B744D275|rigid:r8kOLkaJcNciWCnVNH0aNrs+sIc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61962 uniprotkb:Q9HCM7 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 intact:EBI-6255777|ensembl:ENSP00000396160|uniprotkb:Q86XQ1 psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:fbsl_human(display_long)|uniprotkb:FBRSL1(gene name)|psi-mi:FBRSL1(display_short)|uniprotkb:AUTS2L(gene name synonym)|uniprotkb:KIAA1545(gene name synonym)|uniprotkb:XTP9(gene name synonym)|uniprotkb:AUTS2-like protein(gene name synonym)|uniprotkb:HBV X-transactivated gene 9 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832455|imex:IM-21659-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity)|ddbj/embl/genbank:BC001264(identity) ensembl:ENSG00000112787(gene)|ensembl:ENST00000434748(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR023246|refseq:NP_001136113.1|uniprotkb:Q9HCM7(identity)|entrezgene/locuslink:57666(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rogid:JstP98Bp/L0+GmkLfSdhDHnWmiU9606 intact-crc:91C53749B744D275|rigid:r8kOLkaJcNciWCnVNH0aNrs+sIc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61962 uniprotkb:O15212 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 intact:EBI-356973|ensembl:ENSP00000363734|ensembl:ENSP00000363735|ensembl:ENSP00000363738|ensembl:ENSP00000372694|ensembl:ENSP00000378563|ensembl:ENSP00000382314|ensembl:ENSP00000382316|ensembl:ENSP00000395462|ensembl:ENSP00000398171|ensembl:ENSP00000400152|ensembl:ENSP00000402212|ensembl:ENSP00000402553|ensembl:ENSP00000403771|ensembl:ENSP00000404773|ensembl:ENSP00000412319|ensembl:ENSP00000415678|ensembl:ENSP00000447540|ensembl:ENSP00000448607|ensembl:ENSP00000448784|ensembl:ENSP00000449925 psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:pfd6_human(display_long)|uniprotkb:PFDN6(gene name)|psi-mi:PFDN6(display_short)|uniprotkb:HKE2(gene name synonym)|uniprotkb:PFD6(gene name synonym)|uniprotkb:Protein Ke2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832455|imex:IM-21659-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity)|ddbj/embl/genbank:BC001264(identity) refseq:NP_001172110.1|refseq:NP_055075.1|refseq:NP_001252524.1|refseq:NP_001252525.1|dip:DIP-50304N|ensembl:ENSG00000204220(gene)|ensembl:ENSG00000206283(gene)|ensembl:ENSG00000224782(gene)|ensembl:ENSG00000235692(gene)|ensembl:ENSG00000237335(gene)|ensembl:ENST00000374606(transcript)|ensembl:ENST00000374607(transcript)|ensembl:ENST00000374610(transcript)|ensembl:ENST00000383207(transcript)|ensembl:ENST00000395131(transcript)|ensembl:ENST00000399383(transcript)|ensembl:ENST00000399385(transcript)|ensembl:ENST00000412289(transcript)|ensembl:ENST00000425878(transcript)|ensembl:ENST00000431830(transcript)|ensembl:ENST00000432391(transcript)|ensembl:ENST00000442285(transcript)|ensembl:ENST00000445559(transcript)|ensembl:ENST00000448594(transcript)|ensembl:ENST00000451970(transcript)|ensembl:ENST00000452658(transcript)|ensembl:ENST00000547641(transcript)|ensembl:ENST00000547952(transcript)|ensembl:ENST00000548040(transcript)|ensembl:ENST00000552711(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|mint:O15212|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957|uniprotkb:O15212(identity)|entrezgene/locuslink:10471(identity) psi-mi:"MI:0469"(intact) - crc64:8F138EAAE512A312 figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rogid:t7Z68vuvmprxLIGDh4JhqCGvX+A9606 intact-crc:91C53749B744D275|rigid:r8kOLkaJcNciWCnVNH0aNrs+sIc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61962 uniprotkb:Q53LP3 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 intact:EBI-8832449|uniprotkb:Q9H6U1|uniprotkb:Q8NE15|intact:EBI-28984067|ensembl:ENSP00000365830 psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:swahc_human(display_long)|uniprotkb:ANKRD57(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 57(gene name synonym)|uniprotkb:C2orf26(gene name synonym)|uniprotkb:Protein sosondowah homolog C(gene name synonym)|uniprotkb:SOWAHC(gene name)|psi-mi:SOWAHC(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832455|imex:IM-21659-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity)|ddbj/embl/genbank:BC001264(identity) ensembl:ENSP00000365830|refseq:NP_075392.2|ensembl:ENSG00000198142(gene)|interpro:IPR002110(Ankyrin)|ensembl:ENST00000356454(transcript)|interpro:IPR036770|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9035034|interpro:IPR020683|uniprotkb:Q53LP3(identity)|entrezgene/locuslink:65124(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rogid:vS+1x75B0YAYo5vOoD/ztQm2pLE9606 intact-crc:91C53749B744D275|rigid:r8kOLkaJcNciWCnVNH0aNrs+sIc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61962 uniprotkb:P61758 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 intact:EBI-357430|ensembl:ENSP00000286428|uniprotkb:Q15765|uniprotkb:O55228|uniprotkb:Q5JT81|uniprotkb:Q86X96|uniprotkb:B2R8L5|uniprotkb:B4DWR3|uniprotkb:F5H2A7 psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:pfd3_human(display_long)|uniprotkb:VBP1(gene name)|psi-mi:VBP1(display_short)|uniprotkb:PFDN3(gene name synonym)|uniprotkb:von Hippel-Lindau-binding protein 1(gene name synonym)|uniprotkb:HIBBJ46(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832455|imex:IM-21659-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity)|ddbj/embl/genbank:BC001264(identity) ensembl:ENSG00000155959(gene)|ensembl:ENST00000286428(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006457"(protein folding)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR016655(Prefoldin, subunit 3)|mint:P61758|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957|refseq:NP_003363.1|refseq:NP_001290472.1|refseq:NP_001290474.1|dip:DIP-46479N|refseq:NP_001290473.1|uniprotkb:P61758(identity)|entrezgene/locuslink:7411(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rogid:wHq+HRvhqfKwOaKtONGJdfETQxo9606 intact-crc:91C53749B744D275|rigid:r8kOLkaJcNciWCnVNH0aNrs+sIc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61962 uniprotkb:O60610 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 intact:EBI-3959709|uniprotkb:Q59FH8|uniprotkb:B7ZKW2|uniprotkb:A6NF18|uniprotkb:Q9UC76|intact:EBI-6137912|uniprotkb:E9PEZ2|uniprotkb:Q17RN4|ensembl:ENSP00000373706 psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:diap1_human(display_long)|uniprotkb:DIAPH1(gene name)|psi-mi:DIAPH1(display_short)|uniprotkb:DIAP1(gene name synonym)|uniprotkb:Diaphanous-related formin-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832455|imex:IM-21659-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity)|ddbj/embl/genbank:BC001264(identity) refseq:NP_001073280.1|refseq:NP_005210.3|ensembl:ENSG00000131504(gene)|ensembl:ENST00000389054(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0071420"(cellular response to histamine)|go:"GO:0072686"(mitotic spindle)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR010465(DRF autoregulatory)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014767(Diaphanous autoregulatory)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027653|interpro:IPR042201|mint:O60610|reactome:R-HSA-5663220|reactome:R-HSA-6785631|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013405|reactome:R-HSA-9035034|uniprotkb:O60610(identity)|entrezgene/locuslink:1729(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rogid:m8uSwdWB9ePt8wzBRQBVujfEBfo9606 intact-crc:91C53749B744D275|rigid:r8kOLkaJcNciWCnVNH0aNrs+sIc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61962 uniprotkb:Q9UHV9 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 intact:EBI-359873|uniprotkb:Q9P0P7|uniprotkb:Q9UN05|ensembl:ENSP00000356989 psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:pfd2_human(display_long)|uniprotkb:HSPC231(orf name)|uniprotkb:PFDN2(gene name)|psi-mi:PFDN2(display_short)|uniprotkb:PFD2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832455|imex:IM-21659-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity)|ddbj/embl/genbank:BC001264(identity) refseq:NP_036526.2|refseq:XP_011507926.1|ensembl:ENSG00000143256(gene)|ensembl:ENST00000368010(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|interpro:IPR027235|mint:Q9UHV9|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957|dip:DIP-27557N|uniprotkb:Q9UHV9(identity)|entrezgene/locuslink:5202(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rogid:rgr14h3vGyzHxHoNJtlHBQkvhUE9606 intact-crc:91C53749B744D275|rigid:r8kOLkaJcNciWCnVNH0aNrs+sIc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61962 uniprotkb:Q99832 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091 psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832455|imex:IM-21659-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity)|ddbj/embl/genbank:BC001264(identity) dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|uniprotkb:Q99832(identity)|entrezgene/locuslink:10574(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606 intact-crc:91C53749B744D275|rigid:r8kOLkaJcNciWCnVNH0aNrs+sIc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61962 uniprotkb:P50990 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832455|imex:IM-21659-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity)|ddbj/embl/genbank:BC001264(identity) refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N|uniprotkb:P50990(identity)|entrezgene/locuslink:10694(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 intact-crc:91C53749B744D275|rigid:r8kOLkaJcNciWCnVNH0aNrs+sIc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19784 uniprotkb:P68400 intact:EBI-347451|ensembl:ENSP00000262506 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832343|imex:IM-21659-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|uniprotkb:P19784(identity)|ddbj/embl/genbank:BC008812(identity)|entrezgene/locuslink:1459(identity) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N|uniprotkb:P68400(identity)|entrezgene/locuslink:1457(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 intact-crc:D0F70B117875DEFD|rigid:+Z5gSddvc/Gczzjaq4mmstz/tPQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19784 uniprotkb:O00255 intact:EBI-347451|ensembl:ENSP00000262506 intact:EBI-592789|uniprotkb:O00632|uniprotkb:Q9BUK2|uniprotkb:A5HBC6|uniprotkb:A5HBC7|uniprotkb:A5HBC8|uniprotkb:A5HBC9|uniprotkb:A5HBD0|uniprotkb:A5HBD1|uniprotkb:A5HBD2|uniprotkb:Q9BUF0|ensembl:ENSP00000366530 psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:men1_human(display_long)|uniprotkb:MEN1(gene name)|psi-mi:MEN1(display_short)|uniprotkb:SCG2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832343|imex:IM-21659-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|uniprotkb:P19784(identity)|ddbj/embl/genbank:BC008812(identity)|entrezgene/locuslink:1459(identity) refseq:NP_000235.2|refseq:NP_570711.1|refseq:NP_570712.1|refseq:NP_570713.1|refseq:NP_570714.1|refseq:NP_570715.1|refseq:NP_570716.1|refseq:XP_005274058.1|refseq:XP_016873258.1|refseq:XP_016873259.1|dip:DIP-24236N|ensembl:ENSG00000133895(gene)|ensembl:ENST00000377313(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002076"(osteoblast development)|go:"GO:0003309"(type B pancreatic cell differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032925"(regulation of activin receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046697"(decidualization)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0061469"(regulation of type B pancreatic cell proliferation)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071559"(response to transforming growth factor beta)|go:"GO:1902807"(negative regulation of cell cycle G1/S phase transition)|interpro:IPR007747(Menin)|mint:O00255|rcsb pdb:3U84|rcsb pdb:3U85|rcsb pdb:3U86|rcsb pdb:3U88|rcsb pdb:4GPQ|rcsb pdb:4GQ3|rcsb pdb:4GQ4|rcsb pdb:4GQ6|rcsb pdb:4I80|rcsb pdb:4OG3|rcsb pdb:4OG4|rcsb pdb:4OG5|rcsb pdb:4OG6|rcsb pdb:4OG7|rcsb pdb:4OG8|rcsb pdb:4X5Y|rcsb pdb:4X5Z|rcsb pdb:5DB0|rcsb pdb:5DB1|rcsb pdb:5DB2|rcsb pdb:5DB3|rcsb pdb:5DD9|rcsb pdb:5DDA|rcsb pdb:5DDB|rcsb pdb:5DDC|rcsb pdb:5DDD|rcsb pdb:5DDF|rcsb pdb:6B41|rcsb pdb:6BXH|rcsb pdb:6BXY|rcsb pdb:6BY8|rcsb pdb:6E1A|rcsb pdb:6O5I|rcsb pdb:6OPJ|rcsb pdb:6PKC|rcsb pdb:6WNH|reactome:R-HSA-201722|reactome:R-HSA-2173796|reactome:R-HSA-3769402|reactome:R-HSA-381426|reactome:R-HSA-5626467|reactome:R-HSA-8957275|rcsb pdb:5DDE|uniprotkb:O00255(identity)|entrezgene/locuslink:4221(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 rogid:gXAt4cxheS3wgMbFtc8ACfkHRH09606 intact-crc:D0F70B117875DEFD|rigid:+Z5gSddvc/Gczzjaq4mmstz/tPQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19784 uniprotkb:Q03164 intact:EBI-347451|ensembl:ENSP00000262506 intact:EBI-591370|ensembl:ENSP00000374157|uniprotkb:Q13743|uniprotkb:Q13744|uniprotkb:Q14845|uniprotkb:Q16364|uniprotkb:Q6UBD1|uniprotkb:Q9UMA3|intact:EBI-2614650|uniprotkb:Q59FF2|uniprotkb:Q9UD94|uniprotkb:E9PQG7|uniprotkb:Q9HBJ3 psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:kmt2a_human(display_long)|uniprotkb:KMT2A(gene name)|psi-mi:KMT2A(display_short)|uniprotkb:ALL-1(gene name synonym)|uniprotkb:ALL1(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 7(gene name synonym)|uniprotkb:CXXC7(gene name synonym)|uniprotkb:HRX(gene name synonym)|uniprotkb:HTRX(gene name synonym)|uniprotkb:MLL(gene name synonym)|uniprotkb:MLL1(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 1(gene name synonym)|uniprotkb:TRX1(gene name synonym)|uniprotkb:Trithorax-like protein(gene name synonym)|uniprotkb:Zinc finger protein HRX(gene name synonym)|uniprotkb:Cysteine methyltransferase KMT2A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832343|imex:IM-21659-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|uniprotkb:P19784(identity)|ddbj/embl/genbank:BC008812(identity)|entrezgene/locuslink:1459(identity) go:"GO:2000615"(regulation of histone H3-K9 acetylation)|interpro:IPR001214(SET)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036427|interpro:IPR037927|interpro:IPR041958|interpro:IPR042023|interpro:IPR042025|interpro:IPR044133|mint:Q03164|rcsb pdb:2AGH|rcsb pdb:2J2S|rcsb pdb:2JYI|rcsb pdb:2KKF|rcsb pdb:2KU7|rcsb pdb:2KYU|rcsb pdb:2LXS|rcsb pdb:2LXT|rcsb pdb:2MSR|rcsb pdb:2MTN|rcsb pdb:2W5Y|ensembl:ENSG00000118058(gene)|ensembl:ENST00000389506(transcript)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071440"(regulation of histone H3-K14 acetylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|go:"GO:1905642"(negative regulation of DNA methylation)|refseq:NP_001184033.1|refseq:NP_005924.2|ensembl:ENSP00000374157|ensembl:ENST00000534358|ensembl:ENSP00000436786|ensembl:ENST00000649699|ensembl:ENSP00000496927|dip:DIP-29221N|rcsb pdb:2W5Z|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3LQH|rcsb pdb:3LQI|rcsb pdb:3LQJ|rcsb pdb:3P4F|rcsb pdb:3U85|rcsb pdb:3U88|rcsb pdb:4ESG|rcsb pdb:4GQ6|rcsb pdb:4NW3|rcsb pdb:5F5E|rcsb pdb:5F6L|rcsb pdb:5SVH|rcsb pdb:6EMQ|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U9K|rcsb pdb:6U9M|rcsb pdb:6U9N|rcsb pdb:6U9R|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|reactome:R-HSA-3214841|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9616222|uniprotkb:Q03164(identity)|entrezgene/locuslink:4297(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 rogid:r9J9pjnLZI7GCBSHYqnmzjv9WvM9606 intact-crc:D0F70B117875DEFD|rigid:+Z5gSddvc/Gczzjaq4mmstz/tPQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19784 uniprotkb:Q06587 intact:EBI-347451|ensembl:ENSP00000262506 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832343|imex:IM-21659-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|uniprotkb:P19784(identity)|ddbj/embl/genbank:BC008812(identity)|entrezgene/locuslink:1459(identity) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 intact-crc:D0F70B117875DEFD|rigid:+Z5gSddvc/Gczzjaq4mmstz/tPQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19784 uniprotkb:Q9NY28 intact:EBI-347451|ensembl:ENSP00000262506 intact:EBI-8832338|uniprotkb:B2RU02|ensembl:ENSP00000252318 psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:galt8_human(display_long)|uniprotkb:Polypeptide GalNAc transferase 8(gene name synonym)|uniprotkb:Protein-UDP acetylgalactosaminyltransferase 8(gene name synonym)|uniprotkb:"UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 8"(gene name synonym)|uniprotkb:GALNT8(gene name)|psi-mi:GALNT8(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832343|imex:IM-21659-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|uniprotkb:P19784(identity)|ddbj/embl/genbank:BC008812(identity)|entrezgene/locuslink:1459(identity) refseq:NP_059113.1|ensembl:ENSG00000130035(gene)|ensembl:ENST00000252318(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004653"(polypeptide N-acetylgalactosaminyltransferase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016266"(O-glycan processing)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000772(Ricin B lectin)|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR029044|interpro:IPR035992|reactome:R-HSA-913709|uniprotkb:Q9NY28(identity)|entrezgene/locuslink:26290(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 rogid:CMN5c18tEbqdx88HawXUIFqEDyU9606 intact-crc:D0F70B117875DEFD|rigid:+Z5gSddvc/Gczzjaq4mmstz/tPQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19784 uniprotkb:Q3KNV8 intact:EBI-347451|ensembl:ENSP00000262506 intact:EBI-2339807|uniprotkb:O15262|uniprotkb:D3DVN1|ensembl:ENSP00000354724|ensembl:ENSP00000420489 psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:pcgf3_human(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832343|imex:IM-21659-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|uniprotkb:P19784(identity)|ddbj/embl/genbank:BC008812(identity)|entrezgene/locuslink:1459(identity) refseq:NP_006306.2|refseq:NP_001304765.1|dip:DIP-52782N|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q3KNV8|uniprotkb:Q3KNV8(identity)|entrezgene/locuslink:10336(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606 intact-crc:D0F70B117875DEFD|rigid:+Z5gSddvc/Gczzjaq4mmstz/tPQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19784 uniprotkb:Q9HAH7 intact:EBI-347451|ensembl:ENSP00000262506 intact:EBI-2847800|uniprotkb:Q9H9X4|uniprotkb:Q96CI9|uniprotkb:B4DP86|ensembl:ENSP00000287468 psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:fbrs_human(display_long)|uniprotkb:FBRS(gene name)|psi-mi:FBRS(display_short)|uniprotkb:FBS(gene name synonym)|uniprotkb:FBS1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832343|imex:IM-21659-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|uniprotkb:P19784(identity)|ddbj/embl/genbank:BC008812(identity)|entrezgene/locuslink:1459(identity) refseq:NP_001098549.2|dip:DIP-61357N|ensembl:ENSG00000156860(gene)|ensembl:ENST00000287468(transcript)|interpro:IPR023246|mint:Q9HAH7|uniprotkb:Q9HAH7(identity)|entrezgene/locuslink:64319(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 rogid:n1zkWAYdgwY+t7CFWg5RKO1VSfE9606 intact-crc:D0F70B117875DEFD|rigid:+Z5gSddvc/Gczzjaq4mmstz/tPQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19784 uniprotkb:P61964 intact:EBI-347451|ensembl:ENSP00000262506 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832343|imex:IM-21659-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|uniprotkb:P19784(identity)|ddbj/embl/genbank:BC008812(identity)|entrezgene/locuslink:1459(identity) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|entrezgene/locuslink:11091(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 intact-crc:D0F70B117875DEFD|rigid:+Z5gSddvc/Gczzjaq4mmstz/tPQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19784 uniprotkb:Q8IY57 intact:EBI-347451|ensembl:ENSP00000262506 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832343|imex:IM-21659-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|uniprotkb:P19784(identity)|ddbj/embl/genbank:BC008812(identity)|entrezgene/locuslink:1459(identity) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|entrezgene/locuslink:10138(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 intact-crc:D0F70B117875DEFD|rigid:+Z5gSddvc/Gczzjaq4mmstz/tPQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19784 uniprotkb:Q16543 intact:EBI-347451|ensembl:ENSP00000262506 intact:EBI-295634|uniprotkb:Q53YA2|ensembl:ENSP00000222005 psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:cdc37_human(display_long)|uniprotkb:CDC37(gene name)|psi-mi:CDC37(display_short)|uniprotkb:Hsp90 chaperone protein kinase-targeting subunit(gene name synonym)|uniprotkb:p50Cdc37(gene name synonym)|uniprotkb:CDC37A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832343|imex:IM-21659-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|uniprotkb:P19784(identity)|ddbj/embl/genbank:BC008812(identity)|entrezgene/locuslink:1459(identity) refseq:NP_008996.1|dip:DIP-27560N|ensembl:ENSG00000105401(gene)|ensembl:ENST00000222005(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006605"(protein targeting)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0101031"(chaperone complex)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|interpro:IPR004918(Cdc37)|interpro:IPR013855(Cdc37, N-terminal)|interpro:IPR013873(Cdc37, C-terminal)|interpro:IPR013874(Cdc37, Hsp90 binding)|interpro:IPR038189|mint:Q16543|rcsb pdb:1US7|rcsb pdb:2K5B|rcsb pdb:2N5X|rcsb pdb:2NCA|rcsb pdb:2W0G|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5HPE|reactome:R-HSA-1227986|reactome:R-HSA-1236382|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-9013418|reactome:R-HSA-9634285|reactome:R-HSA-9652282|reactome:R-HSA-9664565|reactome:R-HSA-9665233|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|uniprotkb:Q16543(identity)|entrezgene/locuslink:11140(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 rogid:iajhitd2iEmd17KfpU/nMaKc4049606 intact-crc:D0F70B117875DEFD|rigid:+Z5gSddvc/Gczzjaq4mmstz/tPQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19784 uniprotkb:P61962 intact:EBI-347451|ensembl:ENSP00000262506 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832343|imex:IM-21659-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|uniprotkb:P19784(identity)|ddbj/embl/genbank:BC008812(identity)|entrezgene/locuslink:1459(identity) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 intact-crc:D0F70B117875DEFD|rigid:+Z5gSddvc/Gczzjaq4mmstz/tPQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19784 uniprotkb:Q99496 intact:EBI-347451|ensembl:ENSP00000262506 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832343|imex:IM-21659-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|uniprotkb:P19784(identity)|ddbj/embl/genbank:BC008812(identity)|entrezgene/locuslink:1459(identity) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|entrezgene/locuslink:6045(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 intact-crc:D0F70B117875DEFD|rigid:+Z5gSddvc/Gczzjaq4mmstz/tPQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19784 uniprotkb:P67870 intact:EBI-347451|ensembl:ENSP00000262506 intact:EBI-348169|ensembl:ENSP00000365025|ensembl:ENSP00000365026|ensembl:ENSP00000365042|ensembl:ENSP00000372919|ensembl:ENSP00000372925|ensembl:ENSP00000382980|ensembl:ENSP00000390900|ensembl:ENSP00000391038|ensembl:ENSP00000393756|ensembl:ENSP00000394855|ensembl:ENSP00000395275|ensembl:ENSP00000400188|ensembl:ENSP00000407018|ensembl:ENSP00000407379|ensembl:ENSP00000409510|ensembl:ENSP00000410802|ensembl:ENSP00000411322|ensembl:ENSP00000412520|ensembl:ENSP00000413469|ensembl:ENSP00000415237|ensembl:ENSP00000415303|uniprotkb:P07312|uniprotkb:P13862|uniprotkb:Q4VX47|intact:EBI-3866975|uniprotkb:B0UXA9 psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:csk2b_human(display_long)|uniprotkb:Phosvitin(gene name synonym)|uniprotkb:Protein G5a(gene name synonym)|uniprotkb:CSNK2B(gene name)|psi-mi:CSNK2B(display_short)|uniprotkb:CK2N(gene name synonym)|uniprotkb:G5A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832343|imex:IM-21659-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|uniprotkb:P19784(identity)|ddbj/embl/genbank:BC008812(identity)|entrezgene/locuslink:1459(identity) ensembl:ENSG00000204435(gene)|ensembl:ENSG00000230700(gene)|ensembl:ENSG00000206406(gene)|ensembl:ENSG00000232960(gene)|ensembl:ENSG00000224398(gene)|ensembl:ENSG00000224774(gene)|ensembl:ENSG00000228875(gene)|ensembl:ENST00000375882(transcript)|ensembl:ENST00000383427(transcript)|ensembl:ENST00000383433(transcript)|ensembl:ENST00000400110(transcript)|ensembl:ENST00000412802(transcript)|ensembl:ENST00000418230(transcript)|ensembl:ENST00000422567(transcript)|ensembl:ENST00000429633(transcript)|ensembl:ENST00000431476(transcript)|ensembl:ENST00000436169(transcript)|ensembl:ENST00000443673(transcript)|ensembl:ENST00000448596(transcript)|ensembl:ENST00000451917(transcript)|ensembl:ENST00000452985(transcript)|ensembl:ENST00000453234(transcript)|ensembl:ENST00000454382(transcript)|ensembl:ENST00000454511(transcript)|ensembl:ENST00000455161(transcript)|ensembl:ENST00000458330(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0007165"(signal transduction)|ensembl:ENST00000375865(transcript)|ensembl:ENST00000375866(transcript)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016363"(nuclear matrix)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0034622"|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|mint:P67870|rcsb pdb:1DS5|rcsb pdb:1JWH|go:"GO:0008134"(transcription factor binding)|rcsb pdb:1QF8|rcsb pdb:3EED|rcsb pdb:4DGL|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6798695|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:6Q38|refseq:NP_001311.3|refseq:NP_001269314.1|dip:DIP-131N|uniprotkb:P67870(identity)|entrezgene/locuslink:1460(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 rogid:ZTHJjCqHg2dE7B+WoSU28VSMuPg9606 intact-crc:D0F70B117875DEFD|rigid:+Z5gSddvc/Gczzjaq4mmstz/tPQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19784 uniprotkb:Q9UBL3 intact:EBI-347451|ensembl:ENSP00000262506 intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|ensembl:ENSP00000340896|uniprotkb:A8K7C3|uniprotkb:D3DSW9 psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832343|imex:IM-21659-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|uniprotkb:P19784(identity)|ddbj/embl/genbank:BC008812(identity)|entrezgene/locuslink:1459(identity) refseq:NP_001098684.1|refseq:NP_004665.2|ensembl:ENSG00000129691(gene)|ensembl:ENST00000343823(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|rcsb pdb:4X8N|refseq:NP_001248761.1|dip:DIP-29222N|uniprotkb:Q9UBL3(identity)|entrezgene/locuslink:9070(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606 intact-crc:D0F70B117875DEFD|rigid:+Z5gSddvc/Gczzjaq4mmstz/tPQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19784 uniprotkb:Q9C005 intact:EBI-347451|ensembl:ENSP00000262506 intact:EBI-744973|uniprotkb:D6W578|ensembl:ENSP00000295066|ensembl:ENSP00000345837 psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:dpy30_human(display_long)|uniprotkb:DPY30(gene name)|psi-mi:DPY30(display_short)|uniprotkb:Dpy-30-like protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832343|imex:IM-21659-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|uniprotkb:P19784(identity)|ddbj/embl/genbank:BC008812(identity)|entrezgene/locuslink:1459(identity) refseq:NP_115963.1|ensembl:ENSG00000162961(gene)|ensembl:ENST00000295066(transcript)|ensembl:ENST00000342166(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006348"|go:"GO:0016197"(endosomal transport)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|mint:Q9C005|rcsb pdb:3G36|rcsb pdb:4RIQ|rcsb pdb:4RT4|rcsb pdb:4RTA|rcsb pdb:6E2H|rcsb pdb:6PWV|reactome:R-HSA-3214841|reactome:R-HSA-8936459|refseq:NP_001308138.1|dip:DIP-34476N|uniprotkb:Q9C005(identity)|entrezgene/locuslink:84661(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 rogid:yC9NJhTfEIT+YyfWRSJLGbRsQkc9606 intact-crc:D0F70B117875DEFD|rigid:+Z5gSddvc/Gczzjaq4mmstz/tPQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19784 uniprotkb:O75683 intact:EBI-347451|ensembl:ENSP00000262506 intact:EBI-2691252|uniprotkb:Q9UK24|uniprotkb:Q9BTZ5|uniprotkb:Q5T8U1|uniprotkb:Q9BRK9|ensembl:ENSP00000361092|ensembl:ENSP00000485909 psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:surf6_human(display_long)|uniprotkb:SURF-6(gene name synonym)|uniprotkb:SURF6(gene name)|psi-mi:SURF6(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832343|imex:IM-21659-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|uniprotkb:P19784(identity)|ddbj/embl/genbank:BC008812(identity)|entrezgene/locuslink:1459(identity) refseq:NP_006744.2|refseq:NP_001265871.1|ensembl:ENSG00000148296(gene)|ensembl:ENSG00000281309(gene)|ensembl:ENST00000372022(transcript)|ensembl:ENST00000629980(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR007019(Surfeit locus 6)|interpro:IPR029190|uniprotkb:O75683(identity)|entrezgene/locuslink:6838(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 rogid:1Yzf0+p31xuzJXSoaiz9THfjF0c9606 intact-crc:D0F70B117875DEFD|rigid:+Z5gSddvc/Gczzjaq4mmstz/tPQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19784 uniprotkb:Q15291 intact:EBI-347451|ensembl:ENSP00000262506 intact:EBI-592823|uniprotkb:A8K272|uniprotkb:Q7Z6D8|uniprotkb:Q8NDZ7|ensembl:ENSP00000264515 psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:rbbp5_human(display_long)|uniprotkb:Retinoblastoma-binding protein RBQ-3(gene name synonym)|uniprotkb:RBBP5(gene name)|psi-mi:RBBP5(display_short)|uniprotkb:RBQ3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832343|imex:IM-21659-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|uniprotkb:P19784(identity)|ddbj/embl/genbank:BC008812(identity)|entrezgene/locuslink:1459(identity) refseq:NP_001180201.1|refseq:NP_001180202.1|refseq:NP_005048.2|dip:DIP-29224N|ensembl:ENSG00000117222(gene)|ensembl:ENST00000264515(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037850|mint:Q15291|rcsb pdb:3P4F|rcsb pdb:4X8N|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6KM7|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6PWX|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|uniprotkb:Q15291(identity)|entrezgene/locuslink:5929(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 rogid:Zl8yHcbL1C6StHPyD+875Ccy6gk9606 intact-crc:D0F70B117875DEFD|rigid:+Z5gSddvc/Gczzjaq4mmstz/tPQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19784 uniprotkb:Q8TDD1 intact:EBI-347451|ensembl:ENSP00000262506 intact:EBI-1052503|uniprotkb:Q86YT8|uniprotkb:Q9BRZ1|ensembl:ENSP00000304072 psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:ddx54_human(display_long)|uniprotkb:DEAD box protein 54(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DP97(gene name synonym)|uniprotkb:DEAD box RNA helicase 97 kDa(gene name synonym)|uniprotkb:DDX54(gene name)|psi-mi:DDX54(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832343|imex:IM-21659-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|uniprotkb:P19784(identity)|ddbj/embl/genbank:BC008812(identity)|entrezgene/locuslink:1459(identity) refseq:NP_001104792.1|refseq:NP_076977.3|ensembl:ENSG00000123064(gene)|ensembl:ENST00000306014(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012541(DBP10CT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR033517|mint:Q8TDD1|go:"GO:0003724"(RNA helicase activity)|uniprotkb:Q8TDD1(identity)|entrezgene/locuslink:79039(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 rogid:VzxEkRaOIND08jGJk3yyoztesjo9606 intact-crc:D0F70B117875DEFD|rigid:+Z5gSddvc/Gczzjaq4mmstz/tPQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19784 uniprotkb:Q86SE9 intact:EBI-347451|ensembl:ENSP00000262506 intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492 psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832343|imex:IM-21659-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|uniprotkb:P19784(identity)|ddbj/embl/genbank:BC008812(identity)|entrezgene/locuslink:1459(identity) refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N|uniprotkb:Q86SE9(identity)|entrezgene/locuslink:84333(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606 intact-crc:D0F70B117875DEFD|rigid:+Z5gSddvc/Gczzjaq4mmstz/tPQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19784 uniprotkb:Q9NZM5 intact:EBI-347451|ensembl:ENSP00000262506 intact:EBI-720156|uniprotkb:Q9BTC6|uniprotkb:Q9HAX6|uniprotkb:Q9NPP1|uniprotkb:Q9NPR4|uniprotkb:Q9UFI2|ensembl:ENSP00000246802 psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:nop53_human(display_long)|uniprotkb:NOP53(gene name)|psi-mi:NOP53(display_short)|uniprotkb:GLT(gene name synonym)|uniprotkb:GLTSCR2(gene name synonym)|uniprotkb:Glioma tumor suppressor candidate region gene 2 protein(gene name synonym)|uniprotkb:PICT1(gene name synonym)|uniprotkb:Protein interacting with carboxyl terminus 1(gene name synonym)|uniprotkb:p60(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832343|imex:IM-21659-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|uniprotkb:P19784(identity)|ddbj/embl/genbank:BC008812(identity)|entrezgene/locuslink:1459(identity) refseq:NP_056525.2|ensembl:ENSG00000105373(gene)|ensembl:ENST00000246802(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006364"(rRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0039535"(regulation of RIG-I signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0003723"(RNA binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1901797"(negative regulation of signal transduction by p53 class mediator)|go:"GO:1901837"(negative regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902570"(protein localization to nucleolus)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1990173"(protein localization to nucleoplasm)|interpro:IPR011687(P60-like)|mint:Q9NZM5|go:"GO:0050821"(protein stabilization)|uniprotkb:Q9NZM5(identity)|entrezgene/locuslink:29997(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 rogid:64EYf68f9eP9SfPBJhjbxuJcn2g9606 intact-crc:D0F70B117875DEFD|rigid:+Z5gSddvc/Gczzjaq4mmstz/tPQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19784 uniprotkb:Q9BYG3 intact:EBI-347451|ensembl:ENSP00000262506 intact:EBI-2561019|ensembl:ENSP00000285814|uniprotkb:Q8TB66|uniprotkb:A8K788|uniprotkb:Q96ED4 psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:mk67i_human(display_long)|uniprotkb:NIFK(gene name)|psi-mi:NIFK(display_short)|uniprotkb:MKI67IP(gene name synonym)|uniprotkb:NOPP34(gene name synonym)|uniprotkb:Nucleolar phosphoprotein Nopp34(gene name synonym)|uniprotkb:Nucleolar protein interacting with the FHA domain of pKI-67(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832343|imex:IM-21659-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|uniprotkb:P19784(identity)|ddbj/embl/genbank:BC008812(identity)|entrezgene/locuslink:1459(identity) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009303"(rRNA transcription)|go:"GO:0016072"(rRNA metabolic process)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021043|interpro:IPR035979|mint:Q9BYG3|rcsb pdb:2AFF|ensembl:ENSG00000155438(gene)|ensembl:ENST00000285814(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000794"(condensed nuclear chromosome)|refseq:NP_115766.3|dip:DIP-28134N|uniprotkb:Q9BYG3(identity)|entrezgene/locuslink:84365(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 rogid:DUc8AnzFxJjbK+cTW5H83GQcf6o9606 intact-crc:D0F70B117875DEFD|rigid:+Z5gSddvc/Gczzjaq4mmstz/tPQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H410 uniprotkb:Q9HBM1 intact:EBI-1001144|uniprotkb:E1P5U9|uniprotkb:Q5JW56|uniprotkb:Q9H8P4|ensembl:ENSP00000362855|ensembl:ENSP00000389810|uniprotkb:Q5JW55|uniprotkb:B4DWT2 intact:EBI-999909|ensembl:ENSP00000282074|ensembl:ENSP00000481354|ensembl:ENSP00000483050|uniprotkb:D3DPC0|uniprotkb:A8K4X8 psi-mi:dsn1_human(display_long)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)|uniprotkb:C20orf172(gene name synonym)|uniprotkb:MIS13(gene name synonym) psi-mi:spc25_human(display_long)|uniprotkb:AD024(orf name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)|uniprotkb:SPBC25(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832601|imex:IM-21659-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138789.1|refseq:NP_001138787.1|refseq:NP_001138788.1|refseq:NP_079194.3|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-68877|reactome:R-HSA-9648025|rcsb pdb:5LSK|ensembl:ENSG00000149636(gene)|ensembl:ENST00000373750(transcript)|ensembl:ENST00000426836(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000939"(inner kinetochore)|go:"GO:0001650"(fibrillar center)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0051301"(cell division)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|mint:Q9H410|rcsb pdb:5LSI|rcsb pdb:5LSJ|refseq:NP_001138790.1|refseq:XP_006723939.1|uniprotkb:Q9H410(identity)|ddbj/embl/genbank:BC058899(identity)|entrezgene/locuslink:79980(identity) refseq:NP_065726.1|ensembl:ENSG00000277909(gene)|ensembl:ENST00000282074(transcript)|ensembl:ENST00000611144(transcript)|ensembl:ENST00000616584(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013255(Kinetochore-Ndc80 subunit Spc25)|mint:Q9HBM1|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENSG00000152253(gene)|dip:DIP-35753N|uniprotkb:Q9HBM1(identity)|entrezgene/locuslink:57405(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2015/02/12 rogid:cJ0wCtpLS+YkMj83k/SubkpHwuE9606 rogid:qR1LJPKAJwXtOdzKs4Zg0PqJrBM9606 intact-crc:F24729E402BB5317|rigid:oZCZPIlq30QVh+sywZMGiR/bh8Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H410 uniprotkb:O95229 intact:EBI-1001144|uniprotkb:E1P5U9|uniprotkb:Q5JW56|uniprotkb:Q9H8P4|ensembl:ENSP00000362855|ensembl:ENSP00000389810|uniprotkb:Q5JW55|uniprotkb:B4DWT2 intact:EBI-1001132|uniprotkb:Q9BWD0|ensembl:ENSP00000363055|ensembl:ENSP00000378801|uniprotkb:Q0D2I3|uniprotkb:A6NNV6 psi-mi:dsn1_human(display_long)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)|uniprotkb:C20orf172(gene name synonym)|uniprotkb:MIS13(gene name synonym) psi-mi:zwint_human(display_long)|uniprotkb:ZW10-interacting protein 1(gene name synonym)|uniprotkb:ZWINT(gene name)|psi-mi:ZWINT(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832601|imex:IM-21659-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138789.1|refseq:NP_001138787.1|refseq:NP_001138788.1|refseq:NP_079194.3|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-68877|reactome:R-HSA-9648025|rcsb pdb:5LSK|ensembl:ENSG00000149636(gene)|ensembl:ENST00000373750(transcript)|ensembl:ENST00000426836(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000939"(inner kinetochore)|go:"GO:0001650"(fibrillar center)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0051301"(cell division)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|mint:Q9H410|rcsb pdb:5LSI|rcsb pdb:5LSJ|refseq:NP_001138790.1|refseq:XP_006723939.1|uniprotkb:Q9H410(identity)|ddbj/embl/genbank:BC058899(identity)|entrezgene/locuslink:79980(identity) refseq:NP_001005413.1|refseq:NP_008988.2|refseq:NP_127490.1|go:"GO:0030425"(dendrite)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051301"(cell division)|ensembl:ENSG00000122952(gene)|go:"GO:0051649"(establishment of localization in cell)|interpro:IPR029092|ensembl:ENST00000373944(transcript)|ensembl:ENST00000395405(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|mint:O95229|go:"GO:0005737"(cytoplasm)|reactome:R-HSA-141444|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|reactome:R-HSA-2467813|go:"GO:0016604"(nuclear body)|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|uniprotkb:O95229(identity)|entrezgene/locuslink:11130(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2015/02/12 rogid:cJ0wCtpLS+YkMj83k/SubkpHwuE9606 rogid:iQ5h+pikwo8Yu1MnEjxLtkGg1NE9606 intact-crc:F24729E402BB5317|rigid:oZCZPIlq30QVh+sywZMGiR/bh8Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H410 uniprotkb:Q8NG31 intact:EBI-1001144|uniprotkb:E1P5U9|uniprotkb:Q5JW56|uniprotkb:Q9H8P4|ensembl:ENSP00000362855|ensembl:ENSP00000389810|uniprotkb:Q5JW55|uniprotkb:B4DWT2 intact:EBI-1001161|intact:EBI-2555927|uniprotkb:Q8NHE1|uniprotkb:Q8WXA6|uniprotkb:Q9HCK2|uniprotkb:Q9NR92|ensembl:ENSP00000335463 psi-mi:dsn1_human(display_long)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)|uniprotkb:C20orf172(gene name synonym)|uniprotkb:MIS13(gene name synonym) psi-mi:knl1_human(display_long)|uniprotkb:KNL1(gene name)|psi-mi:KNL1(display_short)|uniprotkb:ALL1-fused gene from chromosome 15q14 protein(gene name synonym)|uniprotkb:Bub-linking kinetochore protein(gene name synonym)|uniprotkb:CASC5(gene name synonym)|uniprotkb:Cancer susceptibility candidate gene 5 protein(gene name synonym)|uniprotkb:Cancer/testis antigen 29(gene name synonym)|uniprotkb:KIAA1570(gene name synonym)|uniprotkb:Kinetochore-null protein 1(gene name synonym)|uniprotkb:Protein CASC5(gene name synonym)|uniprotkb:Protein D40/AF15q14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832601|imex:IM-21659-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138789.1|refseq:NP_001138787.1|refseq:NP_001138788.1|refseq:NP_079194.3|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-68877|reactome:R-HSA-9648025|rcsb pdb:5LSK|ensembl:ENSG00000149636(gene)|ensembl:ENST00000373750(transcript)|ensembl:ENST00000426836(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000939"(inner kinetochore)|go:"GO:0001650"(fibrillar center)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0051301"(cell division)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|mint:Q9H410|rcsb pdb:5LSI|rcsb pdb:5LSJ|refseq:NP_001138790.1|refseq:XP_006723939.1|uniprotkb:Q9H410(identity)|ddbj/embl/genbank:BC058899(identity)|entrezgene/locuslink:79980(identity) ensembl:ENSG00000137812(gene)|ensembl:ENST00000346991(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001675"(acrosome assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016604"(nuclear body)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|interpro:IPR037388|interpro:IPR040850|interpro:IPR043651|mint:Q8NG31|rcsb pdb:3SI5|rcsb pdb:4A1G|rcsb pdb:4NF9|rcsb pdb:4NFA|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_653091.3|refseq:NP_733468.3|ensembl:ENSP00000335463|ensembl:ENST00000399668|ensembl:ENSP00000382576|dip:DIP-36474N|uniprotkb:Q8NG31(identity)|entrezgene/locuslink:57082(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2015/02/12 rogid:cJ0wCtpLS+YkMj83k/SubkpHwuE9606 rogid:VrKgxXm7DGkpFhJjZ98oQhkr5Eo9606 intact-crc:F24729E402BB5317|rigid:oZCZPIlq30QVh+sywZMGiR/bh8Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H410 uniprotkb:Q8NBT2 intact:EBI-1001144|uniprotkb:E1P5U9|uniprotkb:Q5JW56|uniprotkb:Q9H8P4|ensembl:ENSP00000362855|ensembl:ENSP00000389810|uniprotkb:Q5JW55|uniprotkb:B4DWT2 intact:EBI-999900|uniprotkb:C9JGC4|ensembl:ENSP00000465075|uniprotkb:B4DZZ7 psi-mi:dsn1_human(display_long)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)|uniprotkb:C20orf172(gene name synonym)|uniprotkb:MIS13(gene name synonym) psi-mi:spc24_human(display_long)|uniprotkb:SPBC24(gene name synonym)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832601|imex:IM-21659-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138789.1|refseq:NP_001138787.1|refseq:NP_001138788.1|refseq:NP_079194.3|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-68877|reactome:R-HSA-9648025|rcsb pdb:5LSK|ensembl:ENSG00000149636(gene)|ensembl:ENST00000373750(transcript)|ensembl:ENST00000426836(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000939"(inner kinetochore)|go:"GO:0001650"(fibrillar center)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0051301"(cell division)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|mint:Q9H410|rcsb pdb:5LSI|rcsb pdb:5LSJ|refseq:NP_001138790.1|refseq:XP_006723939.1|uniprotkb:Q9H410(identity)|ddbj/embl/genbank:BC058899(identity)|entrezgene/locuslink:79980(identity) refseq:NP_872319.1|ensembl:ENSG00000161888(gene)|ensembl:ENST00000592540(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|mint:Q8NBT2|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001303960.1|refseq:NP_001303962.1|refseq:XP_005259810.1|dip:DIP-35754N|uniprotkb:Q8NBT2(identity)|entrezgene/locuslink:147841(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2015/02/12 rogid:cJ0wCtpLS+YkMj83k/SubkpHwuE9606 rogid:ANMEuzMkpwcbiSjx6OaHAK8vVcA9606 intact-crc:F24729E402BB5317|rigid:oZCZPIlq30QVh+sywZMGiR/bh8Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H410 uniprotkb:Q9H081 intact:EBI-1001144|uniprotkb:E1P5U9|uniprotkb:Q5JW56|uniprotkb:Q9H8P4|ensembl:ENSP00000362855|ensembl:ENSP00000389810|uniprotkb:Q5JW55|uniprotkb:B4DWT2 intact:EBI-1001205|uniprotkb:Q96N24|ensembl:ENSP00000370557|ensembl:ENSP00000461252|ensembl:ENSP00000484532 psi-mi:dsn1_human(display_long)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)|uniprotkb:C20orf172(gene name synonym)|uniprotkb:MIS13(gene name synonym) psi-mi:mis12_human(display_long)|uniprotkb:MIS12(gene name)|psi-mi:MIS12(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832601|imex:IM-21659-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138789.1|refseq:NP_001138787.1|refseq:NP_001138788.1|refseq:NP_079194.3|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-68877|reactome:R-HSA-9648025|rcsb pdb:5LSK|ensembl:ENSG00000149636(gene)|ensembl:ENST00000373750(transcript)|ensembl:ENST00000426836(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000939"(inner kinetochore)|go:"GO:0001650"(fibrillar center)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0051301"(cell division)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|mint:Q9H410|rcsb pdb:5LSI|rcsb pdb:5LSJ|refseq:NP_001138790.1|refseq:XP_006723939.1|uniprotkb:Q9H410(identity)|ddbj/embl/genbank:BC058899(identity)|entrezgene/locuslink:79980(identity) refseq:NP_001245146.1|refseq:NP_001245147.1|refseq:NP_001245148.1|refseq:NP_001245149.1|refseq:XP_016880522.1|refseq:XP_016880523.1|refseq:XP_016880524.1|refseq:NP_076944.1|ensembl:ENSG00000167842(gene)|ensembl:ENST00000381165(transcript)|ensembl:ENST00000573759(transcript)|ensembl:ENST00000611091(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR008685(Mis12)|mint:Q9H081|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_005256854.1|uniprotkb:Q9H081(identity)|entrezgene/locuslink:79003(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2015/02/12 rogid:cJ0wCtpLS+YkMj83k/SubkpHwuE9606 rogid:1qNMwDq3AYOWnRnPa2u3yt7O4109606 intact-crc:F24729E402BB5317|rigid:oZCZPIlq30QVh+sywZMGiR/bh8Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H410 uniprotkb:Q13185 intact:EBI-1001144|uniprotkb:E1P5U9|uniprotkb:Q5JW56|uniprotkb:Q9H8P4|ensembl:ENSP00000362855|ensembl:ENSP00000389810|uniprotkb:Q5JW55|uniprotkb:B4DWT2 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:dsn1_human(display_long)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)|uniprotkb:C20orf172(gene name synonym)|uniprotkb:MIS13(gene name synonym) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832601|imex:IM-21659-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138789.1|refseq:NP_001138787.1|refseq:NP_001138788.1|refseq:NP_079194.3|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-68877|reactome:R-HSA-9648025|rcsb pdb:5LSK|ensembl:ENSG00000149636(gene)|ensembl:ENST00000373750(transcript)|ensembl:ENST00000426836(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000939"(inner kinetochore)|go:"GO:0001650"(fibrillar center)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0051301"(cell division)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|mint:Q9H410|rcsb pdb:5LSI|rcsb pdb:5LSJ|refseq:NP_001138790.1|refseq:XP_006723939.1|uniprotkb:Q9H410(identity)|ddbj/embl/genbank:BC058899(identity)|entrezgene/locuslink:79980(identity) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2015/02/12 rogid:cJ0wCtpLS+YkMj83k/SubkpHwuE9606 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 intact-crc:F24729E402BB5317|rigid:oZCZPIlq30QVh+sywZMGiR/bh8Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H410 uniprotkb:Q9BZD4 intact:EBI-1001144|uniprotkb:E1P5U9|uniprotkb:Q5JW56|uniprotkb:Q9H8P4|ensembl:ENSP00000362855|ensembl:ENSP00000389810|uniprotkb:Q5JW55|uniprotkb:B4DWT2 intact:EBI-724102|ensembl:ENSP00000271452|ensembl:ENSP00000356875|uniprotkb:Q8WU69|uniprotkb:Q96HJ4|uniprotkb:Q96Q78 psi-mi:dsn1_human(display_long)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)|uniprotkb:C20orf172(gene name synonym)|uniprotkb:MIS13(gene name synonym) psi-mi:nuf2_human(display_long)|uniprotkb:NUF2(gene name)|psi-mi:NUF2(display_short)|uniprotkb:CDCA1(gene name synonym)|uniprotkb:NUF2R(gene name synonym)|uniprotkb:Cell division cycle-associated protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832601|imex:IM-21659-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138789.1|refseq:NP_001138787.1|refseq:NP_001138788.1|refseq:NP_079194.3|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-68877|reactome:R-HSA-9648025|rcsb pdb:5LSK|ensembl:ENSG00000149636(gene)|ensembl:ENST00000373750(transcript)|ensembl:ENST00000426836(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000939"(inner kinetochore)|go:"GO:0001650"(fibrillar center)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0051301"(cell division)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|mint:Q9H410|rcsb pdb:5LSI|rcsb pdb:5LSJ|refseq:NP_001138790.1|refseq:XP_006723939.1|uniprotkb:Q9H410(identity)|ddbj/embl/genbank:BC058899(identity)|entrezgene/locuslink:79980(identity) refseq:NP_113611.2|refseq:NP_663735.2|ensembl:ENSG00000143228(gene)|ensembl:ENST00000271452(transcript)|ensembl:ENST00000367900(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|interpro:IPR005549(Nuf2)|interpro:IPR038275|mint:Q9BZD4|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|go:"GO:0016020"(membrane)|dip:DIP-36119N|uniprotkb:Q9BZD4(identity)|entrezgene/locuslink:83540(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2015/02/12 rogid:cJ0wCtpLS+YkMj83k/SubkpHwuE9606 rogid:jyetvY/NG1CPYYsx5DZ4dVEPdEY9606 intact-crc:F24729E402BB5317|rigid:oZCZPIlq30QVh+sywZMGiR/bh8Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H410 uniprotkb:P45973 intact:EBI-1001144|uniprotkb:E1P5U9|uniprotkb:Q5JW56|uniprotkb:Q9H8P4|ensembl:ENSP00000362855|ensembl:ENSP00000389810|uniprotkb:Q5JW55|uniprotkb:B4DWT2 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 psi-mi:dsn1_human(display_long)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)|uniprotkb:C20orf172(gene name synonym)|uniprotkb:MIS13(gene name synonym) psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832601|imex:IM-21659-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138789.1|refseq:NP_001138787.1|refseq:NP_001138788.1|refseq:NP_079194.3|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-68877|reactome:R-HSA-9648025|rcsb pdb:5LSK|ensembl:ENSG00000149636(gene)|ensembl:ENST00000373750(transcript)|ensembl:ENST00000426836(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000939"(inner kinetochore)|go:"GO:0001650"(fibrillar center)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0051301"(cell division)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|mint:Q9H410|rcsb pdb:5LSI|rcsb pdb:5LSJ|refseq:NP_001138790.1|refseq:XP_006723939.1|uniprotkb:Q9H410(identity)|ddbj/embl/genbank:BC058899(identity)|entrezgene/locuslink:79980(identity) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|entrezgene/locuslink:23468(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2015/02/12 rogid:cJ0wCtpLS+YkMj83k/SubkpHwuE9606 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 intact-crc:F24729E402BB5317|rigid:oZCZPIlq30QVh+sywZMGiR/bh8Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H410 uniprotkb:Q6P1K2 intact:EBI-1001144|uniprotkb:E1P5U9|uniprotkb:Q5JW56|uniprotkb:Q9H8P4|ensembl:ENSP00000362855|ensembl:ENSP00000389810|uniprotkb:Q5JW55|uniprotkb:B4DWT2 intact:EBI-713832|uniprotkb:Q5TCJ8|uniprotkb:Q5TCJ9|uniprotkb:Q5TCK3|uniprotkb:Q69YZ9|uniprotkb:Q6PHR4|uniprotkb:Q86VJ6|uniprotkb:Q8N4T6|uniprotkb:Q9UBQ3|uniprotkb:A8K0C5|intact:EBI-2554676|uniprotkb:Q5TCK0|ensembl:ENSP00000357260|uniprotkb:Q5TCK1|uniprotkb:Q6ZVE6 psi-mi:dsn1_human(display_long)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)|uniprotkb:C20orf172(gene name synonym)|uniprotkb:MIS13(gene name synonym) psi-mi:pmf1_human(display_long)|uniprotkb:PMF1(gene name)|psi-mi:PMF1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832601|imex:IM-21659-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138789.1|refseq:NP_001138787.1|refseq:NP_001138788.1|refseq:NP_079194.3|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-68877|reactome:R-HSA-9648025|rcsb pdb:5LSK|ensembl:ENSG00000149636(gene)|ensembl:ENST00000373750(transcript)|ensembl:ENST00000426836(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000939"(inner kinetochore)|go:"GO:0001650"(fibrillar center)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0051301"(cell division)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|mint:Q9H410|rcsb pdb:5LSI|rcsb pdb:5LSJ|refseq:NP_001138790.1|refseq:XP_006723939.1|uniprotkb:Q9H410(identity)|ddbj/embl/genbank:BC058899(identity)|entrezgene/locuslink:79980(identity) ensembl:ENSG00000160783(gene)|ensembl:ENST00000368277(transcript)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0051301"(cell division)|interpro:IPR007128(Nnf1)|mint:Q6P1K2|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001186582.1|refseq:NP_001186583.1|refseq:NP_001186590.1|refseq:NP_001186592.1|refseq:NP_009152.2|uniprotkb:Q6P1K2(identity)|entrezgene/locuslink:11243(identity)|entrezgene/locuslink:100527963(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2015/02/12 rogid:cJ0wCtpLS+YkMj83k/SubkpHwuE9606 rogid:76xPGmFgI3Pt1gsZMb3aD4hpPWM9606 intact-crc:F24729E402BB5317|rigid:oZCZPIlq30QVh+sywZMGiR/bh8Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H410 uniprotkb:O14777 intact:EBI-1001144|uniprotkb:E1P5U9|uniprotkb:Q5JW56|uniprotkb:Q9H8P4|ensembl:ENSP00000362855|ensembl:ENSP00000389810|uniprotkb:Q5JW55|uniprotkb:B4DWT2 intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597 psi-mi:dsn1_human(display_long)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)|uniprotkb:C20orf172(gene name synonym)|uniprotkb:MIS13(gene name synonym) psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832601|imex:IM-21659-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138789.1|refseq:NP_001138787.1|refseq:NP_001138788.1|refseq:NP_079194.3|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-68877|reactome:R-HSA-9648025|rcsb pdb:5LSK|ensembl:ENSG00000149636(gene)|ensembl:ENST00000373750(transcript)|ensembl:ENST00000426836(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000939"(inner kinetochore)|go:"GO:0001650"(fibrillar center)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0051301"(cell division)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|mint:Q9H410|rcsb pdb:5LSI|rcsb pdb:5LSJ|refseq:NP_001138790.1|refseq:XP_006723939.1|uniprotkb:Q9H410(identity)|ddbj/embl/genbank:BC058899(identity)|entrezgene/locuslink:79980(identity) refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N|uniprotkb:O14777(identity)|entrezgene/locuslink:10403(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2015/02/12 rogid:cJ0wCtpLS+YkMj83k/SubkpHwuE9606 rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606 intact-crc:F24729E402BB5317|rigid:oZCZPIlq30QVh+sywZMGiR/bh8Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H410 uniprotkb:Q96IY1 intact:EBI-1001144|uniprotkb:E1P5U9|uniprotkb:Q5JW56|uniprotkb:Q9H8P4|ensembl:ENSP00000362855|ensembl:ENSP00000389810|uniprotkb:Q5JW55|uniprotkb:B4DWT2 intact:EBI-2554690|uniprotkb:Q9H2M5|uniprotkb:Q5SY75|uniprotkb:Q9Y415|uniprotkb:Q9NRN8|ensembl:ENSP00000355944|uniprotkb:E7ETD5 psi-mi:dsn1_human(display_long)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)|uniprotkb:C20orf172(gene name synonym)|uniprotkb:MIS13(gene name synonym) psi-mi:nsl1_human(display_long)|uniprotkb:C1orf48(gene name synonym)|uniprotkb:DC8(orf name)|uniprotkb:DC31(orf name)|uniprotkb:MIS14(orf name)|uniprotkb:NSL1(gene name)|psi-mi:NSL1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832601|imex:IM-21659-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138789.1|refseq:NP_001138787.1|refseq:NP_001138788.1|refseq:NP_079194.3|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-68877|reactome:R-HSA-9648025|rcsb pdb:5LSK|ensembl:ENSG00000149636(gene)|ensembl:ENST00000373750(transcript)|ensembl:ENST00000426836(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000939"(inner kinetochore)|go:"GO:0001650"(fibrillar center)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0051301"(cell division)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|mint:Q9H410|rcsb pdb:5LSI|rcsb pdb:5LSJ|refseq:NP_001138790.1|refseq:XP_006723939.1|uniprotkb:Q9H410(identity)|ddbj/embl/genbank:BC058899(identity)|entrezgene/locuslink:79980(identity) refseq:NP_056286.3|ensembl:ENSG00000117697(gene)|ensembl:ENST00000366977(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|go:"GO:0051301"(cell division)|interpro:IPR013950(Kinetochore Mis14)|mint:Q96IY1|rcsb pdb:4NF9|rcsb pdb:5LSI|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-2500257|reactome:R-HSA-9648025|refseq:NP_001036014.1|uniprotkb:Q96IY1(identity)|entrezgene/locuslink:25936(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2015/02/12 rogid:cJ0wCtpLS+YkMj83k/SubkpHwuE9606 rogid:w4K2MEHLfZvFECNhtDanXWF0LQk9606 intact-crc:F24729E402BB5317|rigid:oZCZPIlq30QVh+sywZMGiR/bh8Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75461 uniprotkb:Q7Z4G1 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 intact:EBI-1550081|uniprotkb:A6NF28|uniprotkb:Q5TBK4|uniprotkb:B7ZLN0|ensembl:ENSP00000366841|ensembl:ENSP00000506987 psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:comd6_human(display_long)|uniprotkb:COMMD6(gene name)|psi-mi:COMMD6(display_short)|uniprotkb:MSTP076(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832656|imex:IM-21659-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity)|ddbj/embl/genbank:BC008348(identity) refseq:NP_987091.1|refseq:NP_987093.1|ensembl:ENSG00000188243(gene)|ensembl:ENST00000377615(transcript)|ensembl:ENST00000682242(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0051059"(NF-kappaB binding)|interpro:IPR017920|reactome:R-HSA-8951664|uniprotkb:Q7Z4G1(identity)|entrezgene/locuslink:170622(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rogid:73rTIbUABTRqe9OabTgdQ1QvZ7A9606 intact-crc:94D10CA3FCC01EB5|rigid:gbKfrlEraT52VX+fQoSuXRgM9a8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75461 uniprotkb:P01036 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 intact:EBI-1049999|uniprotkb:Q9UBI5|uniprotkb:Q9UCS9|ensembl:ENSP00000217423 psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:cyts_human(display_long)|uniprotkb:Cystatin-4(gene name synonym)|uniprotkb:Salivary acidic protein 1(gene name synonym)|uniprotkb:Cystatin-SA-III(gene name synonym)|uniprotkb:CST4(gene name)|psi-mi:CST4(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832656|imex:IM-21659-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity)|ddbj/embl/genbank:BC008348(identity) refseq:NP_001890.1|ensembl:ENSG00000101441(gene)|ensembl:ENST00000217423(transcript)|go:"GO:0001580"(detection of chemical stimulus involved in sensory perception of bitter taste)|go:"GO:0001895"(retina homeostasis)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR018073|uniprotkb:P01036(identity)|entrezgene/locuslink:1472(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rogid:3mgJvz2gf5kf34cZ9NrAzXxuSyI9606 intact-crc:94D10CA3FCC01EB5|rigid:gbKfrlEraT52VX+fQoSuXRgM9a8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75461 uniprotkb:P09228 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 intact:EBI-8832659|uniprotkb:Q9UCQ7|ensembl:ENSP00000307540 psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:cytt_human(display_long)|uniprotkb:Cystatin-2(gene name synonym)|uniprotkb:Cystatin-S5(gene name synonym)|uniprotkb:CST2(gene name)|psi-mi:CST2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832656|imex:IM-21659-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity)|ddbj/embl/genbank:BC008348(identity) refseq:NP_001313.1|ensembl:ENSG00000170369(gene)|ensembl:ENST00000304725(transcript)|go:"GO:0001580"(detection of chemical stimulus involved in sensory perception of bitter taste)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR018073|uniprotkb:P09228(identity)|entrezgene/locuslink:1470(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rogid:ENojGWjjDakgEa9/eK4UN/rMJmk9606 intact-crc:94D10CA3FCC01EB5|rigid:gbKfrlEraT52VX+fQoSuXRgM9a8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75461 uniprotkb:P02814 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 intact:EBI-738612|uniprotkb:Q9UBN0|uniprotkb:Q9UCT0|uniprotkb:B7ZMG7|ensembl:ENSP00000302400|ensembl:ENSP00000423138 psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:smr3b_human(display_long)|uniprotkb:SMR3B(gene name)|psi-mi:SMR3B(display_short)|uniprotkb:PBII(gene name synonym)|uniprotkb:PRL3(gene name synonym)|uniprotkb:Proline-rich protein 3(gene name synonym)|uniprotkb:Proline-rich peptide P-B(gene name synonym)|uniprotkb:PROL3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832656|imex:IM-21659-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity)|ddbj/embl/genbank:BC008348(identity) refseq:NP_006676.1|ensembl:ENSG00000171201(gene)|ensembl:ENST00000304915(transcript)|ensembl:ENST00000504825(transcript)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0070062"(extracellular exosome)|interpro:IPR026288|mint:P02814|uniprotkb:P02814(identity)|entrezgene/locuslink:10879(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rogid:WJ7Ag6lcBGK16pBo7LaEWJ1hydg9606 intact-crc:94D10CA3FCC01EB5|rigid:gbKfrlEraT52VX+fQoSuXRgM9a8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75461 uniprotkb:Q8N668 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 intact:EBI-1550112|uniprotkb:Q96GS0|uniprotkb:B4DFQ4|ensembl:ENSP00000308236 psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:comd1_human(display_long)|uniprotkb:COMMD1(gene name)|psi-mi:COMMD1(display_short)|uniprotkb:C2orf5(gene name synonym)|uniprotkb:MURR1(gene name synonym)|uniprotkb:Protein Murr1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832656|imex:IM-21659-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity)|ddbj/embl/genbank:BC008348(identity) refseq:NP_689729.1|ensembl:ENSG00000173163(gene)|ensembl:ENST00000311832(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR017920|interpro:IPR033776|interpro:IPR037351|mint:Q8N668|rcsb pdb:2H2M|reactome:R-HSA-8951664|uniprotkb:Q8N668(identity)|entrezgene/locuslink:150684(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rogid:b4sVuz5jwndjw+8ejRFqOcLRk1I9606 intact-crc:94D10CA3FCC01EB5|rigid:gbKfrlEraT52VX+fQoSuXRgM9a8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75461 uniprotkb:P04792 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 intact:EBI-352682|uniprotkb:Q6FI47|uniprotkb:Q96C20|uniprotkb:Q96EI7|uniprotkb:Q9UC34|uniprotkb:Q9UC35|uniprotkb:Q9UC36|uniprotkb:Q9UC31|ensembl:ENSP00000248553|uniprotkb:B2R4N8 psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:hspb1_human(display_long)|uniprotkb:HSPB1(gene name)|psi-mi:HSPB1(display_short)|uniprotkb:HSP27(gene name synonym)|uniprotkb:HSP28(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Stress-responsive protein 27(gene name synonym)|uniprotkb:Estrogen-regulated 24 kDa protein(gene name synonym)|uniprotkb:28 kDa heat shock protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832656|imex:IM-21659-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity)|ddbj/embl/genbank:BC008348(identity) refseq:NP_001531.1|ensembl:ENSG00000106211(gene)|ensembl:ENST00000248553(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038033"(positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P04792|rcsb pdb:2N3J|rcsb pdb:3Q9P|rcsb pdb:3Q9Q|rcsb pdb:4MJH|rcsb pdb:6DV5|rcsb pdb:6GJH|reactome:R-HSA-4420097|reactome:R-HSA-450408|reactome:R-HSA-5687128|reactome:R-HSA-9009391|dip:DIP-412N|uniprotkb:P04792(identity)|entrezgene/locuslink:3315(identity) psi-mi:"MI:0469"(intact) - crc64:1B4DC44A6F6606D5 figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rogid:vrDXIdzP30aHSDLHOh2D4x54eJY9606 intact-crc:94D10CA3FCC01EB5|rigid:gbKfrlEraT52VX+fQoSuXRgM9a8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75461 uniprotkb:P47929 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 intact:EBI-357504|ensembl:ENSP00000313571|ensembl:ENSP00000367891|ensembl:ENSP00000489395|ensembl:ENSP00000489582|uniprotkb:Q6IB87 psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:leg7_human(display_long)|uniprotkb:LGALS7(gene name)|psi-mi:LGALS7(display_short)|uniprotkb:PIG1(gene name synonym)|uniprotkb:HKL-14(gene name synonym)|uniprotkb:PI7(gene name synonym)|uniprotkb:p53-induced gene 1 protein(gene name synonym)|uniprotkb:LGALS7B(gene name)|psi-mi:LGALS7B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832656|imex:IM-21659-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity)|ddbj/embl/genbank:BC008348(identity) ensembl:ENSG00000178934(gene)|ensembl:ENSG00000205076(gene)|ensembl:ENSG00000282902(gene)|ensembl:ENSG00000283082(gene)|ensembl:ENST00000314980(transcript)|ensembl:ENST00000378626(transcript)|ensembl:ENST00000634448(transcript)|ensembl:ENST00000634800(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016936"(galactoside binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000562"(negative regulation of CD4-positive, alpha-beta T cell proliferation)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030640|interpro:IPR044156|mint:P47929|rcsb pdb:1BKZ|rcsb pdb:2GAL|rcsb pdb:3GAL|rcsb pdb:3ZXE|rcsb pdb:3ZXF|rcsb pdb:4GAL|rcsb pdb:4UW3|rcsb pdb:4UW4|rcsb pdb:4UW5|rcsb pdb:4UW6|rcsb pdb:4XBQ|rcsb pdb:4Y26|rcsb pdb:5GAL|rcsb pdb:5H9Q|rcsb pdb:5H9S|refseq:NP_001035972.1|refseq:NP_002298.1|uniprotkb:P47929(identity)|entrezgene/locuslink:653499(identity)|entrezgene/locuslink:3963(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rogid:TIAlvVZ7rOYqTAGrYAFbJY231gc9606 intact-crc:94D10CA3FCC01EB5|rigid:gbKfrlEraT52VX+fQoSuXRgM9a8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75461 uniprotkb:P00367 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 intact:EBI-356544|uniprotkb:Q5TBU3|ensembl:ENSP00000277865|uniprotkb:B3KV55|uniprotkb:B4DGN5 psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:dhe3_human(display_long)|uniprotkb:GLUD1(gene name)|psi-mi:GLUD1(display_short)|uniprotkb:GLUD(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832656|imex:IM-21659-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity)|ddbj/embl/genbank:BC008348(identity) ensembl:ENSG00000148672(gene)|ensembl:ENST00000277865(transcript)|go:"GO:0004352"("glutamate dehydrogenase (NAD+) activity")|go:"GO:0004353"("glutamate dehydrogenase [NAD(P)+] activity")|go:"GO:0004354"("glutamate dehydrogenase (NADP+) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0042802"(identical protein binding)|refseq:NP_005262.1|refseq:NP_001305829.1|refseq:NP_001305830.1|refseq:NP_001305831.1|refseq:NP_001305833.1|refseq:NP_001305834.1|refseq:NP_001305835.1|go:"GO:0043531"(ADP binding)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070728"(leucine binding)|go:"GO:0072350"(tricarboxylic acid metabolic process)|interpro:IPR006095(Glutamate/phenylalanine/leucine/valine dehydrogenase)|interpro:IPR006096(Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal)|interpro:IPR006097(Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation region)|interpro:IPR033524|interpro:IPR033922|interpro:IPR036291|mint:P00367|rcsb pdb:1L1F|rcsb pdb:1NR1|rcsb pdb:6DQG|reactome:R-HSA-2151201|reactome:R-HSA-8964539|uniprotkb:P00367(identity)|entrezgene/locuslink:2746(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rogid:rWYi7otiOLlUvfEl7Vy6ELkY+BM9606 intact-crc:94D10CA3FCC01EB5|rigid:gbKfrlEraT52VX+fQoSuXRgM9a8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75461 uniprotkb:Q8IY57 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832656|imex:IM-21659-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity)|ddbj/embl/genbank:BC008348(identity) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|entrezgene/locuslink:10138(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 intact-crc:94D10CA3FCC01EB5|rigid:gbKfrlEraT52VX+fQoSuXRgM9a8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75461 uniprotkb:P05089 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 intact:EBI-2513844|uniprotkb:Q5JWT6|uniprotkb:Q5JWT5|uniprotkb:Q9BS50|uniprotkb:Q8TE72|uniprotkb:A6NEA0|ensembl:ENSP00000357066 psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:argi1_human(display_long)|uniprotkb:ARG1(gene name)|psi-mi:ARG1(display_short)|uniprotkb:Type I arginase(gene name synonym)|uniprotkb:Liver-type arginase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832656|imex:IM-21659-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity)|ddbj/embl/genbank:BC008348(identity) refseq:NP_000036.2|refseq:NP_001231367.1|ensembl:ENSG00000118520(gene)|ensembl:ENST00000368087(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0001889"(liver development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004053"(arginase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006527"(arginine catabolic process)|go:"GO:0007568"(aging)|go:"GO:0009635"(response to herbicide)|go:"GO:0010042"(response to manganese ion)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010963"|go:"GO:0014075"(response to amine)|go:"GO:0019547"(arginine catabolic process to ornithine)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030324"(lung development)|go:"GO:0032964"(collagen biosynthetic process)|go:"GO:0033189"(response to vitamin A)|go:"GO:0033197"(response to vitamin E)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043200"(response to amino acid)|go:"GO:0045087"(innate immune response)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048678"(response to axon injury)|go:"GO:0051597"(response to methylmercury)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070965"(positive regulation of neutrophil mediated killing of fungus)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071377"(cellular response to glucagon stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:2000552"(negative regulation of T-helper 2 cell cytokine production)|interpro:IPR006035(Ureohydrolase)|interpro:IPR014033(Arginase, subgroup)|go:"GO:0060056"(mammary gland involution)|interpro:IPR020855|interpro:IPR023696|mint:P05089|rcsb pdb:1WVA|rcsb pdb:1WVB|rcsb pdb:2AEB|rcsb pdb:2PHA|rcsb pdb:2PHO|rcsb pdb:2PLL|rcsb pdb:2ZAV|rcsb pdb:3DJ8|rcsb pdb:3E6K|rcsb pdb:3E6V|rcsb pdb:3F80|rcsb pdb:3GMZ|rcsb pdb:3GN0|rcsb pdb:3KV2|rcsb pdb:3LP4|rcsb pdb:3LP7|rcsb pdb:3MFV|rcsb pdb:3MFW|rcsb pdb:3MJL|rcsb pdb:3SJT|rcsb pdb:3SKK|rcsb pdb:3TF3|rcsb pdb:3TH7|rcsb pdb:3THE|rcsb pdb:3THH|rcsb pdb:3THJ|rcsb pdb:4FCI|rcsb pdb:4FCK|rcsb pdb:4GSM|rcsb pdb:4GSV|rcsb pdb:4GSZ|rcsb pdb:4GWC|rcsb pdb:4GWD|rcsb pdb:4HWW|rcsb pdb:4HXQ|rcsb pdb:4IE1|rcsb pdb:6Q92|rcsb pdb:6Q9P|rcsb pdb:6QAF|rcsb pdb:6V7C|rcsb pdb:6V7D|rcsb pdb:6V7E|rcsb pdb:6V7F|reactome:R-HSA-6798695|reactome:R-HSA-70635|uniprotkb:P05089(identity)|entrezgene/locuslink:383(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rogid:b8HHscDekWZdN1S4OxFTA6rjvn89606 intact-crc:94D10CA3FCC01EB5|rigid:gbKfrlEraT52VX+fQoSuXRgM9a8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75461 uniprotkb:P31151 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 intact:EBI-357520|uniprotkb:Q6FGE3|uniprotkb:Q5SY67|uniprotkb:Q9H1E2|ensembl:ENSP00000357711|ensembl:ENSP00000357712 psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:s10a7_human(display_long)|uniprotkb:S100A7(gene name)|psi-mi:S100A7(display_short)|uniprotkb:PSOR1(gene name synonym)|uniprotkb:S100A7C(gene name synonym)|uniprotkb:S100 calcium-binding protein A7(gene name synonym)|uniprotkb:Psoriasin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832656|imex:IM-21659-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity)|ddbj/embl/genbank:BC008348(identity) ensembl:ENSG00000143556(gene)|ensembl:ENST00000368722(transcript)|ensembl:ENST00000368723(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001525"(angiogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008544"(epidermis development)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045087"(innate immune response)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051238"(sequestering of metal ion)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071624"(positive regulation of granulocyte chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028477|interpro:IPR034325|mint:P31151|rcsb pdb:1PSR|rcsb pdb:2PSR|rcsb pdb:2WND|rcsb pdb:2WOR|rcsb pdb:2WOS|rcsb pdb:3PSR|rcsb pdb:4AQJ|reactome:R-HSA-6798695|reactome:R-HSA-6799990|refseq:NP_002954.2|uniprotkb:P31151(identity)|entrezgene/locuslink:6278(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rogid:/v8+XQ7rCMTYzq9k/KqjcSm/G0A9606 intact-crc:94D10CA3FCC01EB5|rigid:gbKfrlEraT52VX+fQoSuXRgM9a8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75461 uniprotkb:P09211 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 intact:EBI-353467|uniprotkb:O00460|uniprotkb:Q15690|ensembl:ENSP00000381607|uniprotkb:Q5TZY3 psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:gstp1_human(display_long)|uniprotkb:GSTP1(gene name)|psi-mi:GSTP1(display_short)|uniprotkb:GST3(gene name synonym)|uniprotkb:FAEES3(gene name synonym)|uniprotkb:GST class-pi(gene name synonym)|uniprotkb:GSTP1-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832656|imex:IM-21659-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity)|ddbj/embl/genbank:BC008348(identity) refseq:NP_000843.1|ensembl:ENSG00000084207(gene)|go:"GO:0000302"(response to reactive oxygen species)|ensembl:ENST00000398606(transcript)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006693"(prostaglandin metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0009890"(negative regulation of biosynthetic process)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0019207"(kinase regulator activity)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031982"(vesicle)|go:"GO:0032355"(response to estradiol)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033591"(response to L-ascorbic acid)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035726"(common myeloid progenitor cell proliferation)|go:"GO:0035730"(S-nitrosoglutathione binding)|go:"GO:0035731"(dinitrosyl-iron complex binding)|go:"GO:0035732"(nitric oxide storage)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0043651"(linoleic acid metabolic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051122"(hepoxilin biosynthetic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003082(Glutathione S-transferase, Pi class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|mint:P09211|rcsb pdb:10GS|rcsb pdb:11GS|rcsb pdb:12GS|rcsb pdb:13GS|rcsb pdb:14GS|rcsb pdb:16GS|rcsb pdb:17GS|rcsb pdb:18GS|rcsb pdb:19GS|rcsb pdb:1AQV|rcsb pdb:1AQW|rcsb pdb:1AQX|rcsb pdb:1EOG|rcsb pdb:1EOH|rcsb pdb:1GSS|rcsb pdb:1KBN|rcsb pdb:1LBK|rcsb pdb:1MD3|rcsb pdb:1MD4|rcsb pdb:1PGT|rcsb pdb:1PX6|rcsb pdb:1PX7|rcsb pdb:1ZGN|rcsb pdb:20GS|rcsb pdb:22GS|rcsb pdb:2A2R|rcsb pdb:2A2S|rcsb pdb:2GSS|rcsb pdb:2J9H|rcsb pdb:2PGT|rcsb pdb:3CSH|rcsb pdb:3CSI|rcsb pdb:3CSJ|rcsb pdb:3DD3|rcsb pdb:3DGQ|rcsb pdb:3GSS|rcsb pdb:3GUS|rcsb pdb:3HJM|rcsb pdb:3HJO|rcsb pdb:3HKR|rcsb pdb:3IE3|rcsb pdb:3KM6|rcsb pdb:3KMN|rcsb pdb:3KMO|rcsb pdb:3N9J|rcsb pdb:3PGT|rcsb pdb:4GSS|rcsb pdb:4PGT|rcsb pdb:5DAK|rcsb pdb:5DAL|rcsb pdb:5DCG|rcsb pdb:5DDL|rcsb pdb:5DJL|rcsb pdb:5DJM|rcsb pdb:5GSS|rcsb pdb:5J41|rcsb pdb:5JCW|rcsb pdb:5L6X|rcsb pdb:5X79|rcsb pdb:6AP9|rcsb pdb:6GSS|rcsb pdb:6LLX|rcsb pdb:6Y1E|rcsb pdb:7GSS|rcsb pdb:8GSS|rcsb pdb:9GSS|reactome:R-HSA-156590|reactome:R-HSA-3299685|reactome:R-HSA-6798695|go:"GO:0051771"(negative regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0070026"(nitric oxide binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070664"(negative regulation of leukocyte proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071460"(cellular response to cell-matrix adhesion)|go:"GO:0071638"(negative regulation of monocyte chemotactic protein-1 production)|go:"GO:0071672"(negative regulation of smooth muscle cell chemotaxis)|go:"GO:0097057"(TRAF2-GSTP1 complex)|go:"GO:1901687"(glutathione derivative biosynthetic process)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|uniprotkb:P09211(identity)|entrezgene/locuslink:2950(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rogid:JxqbNusNIvkTg3Cq+7pmygP/EIA9606 intact-crc:94D10CA3FCC01EB5|rigid:gbKfrlEraT52VX+fQoSuXRgM9a8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75461 uniprotkb:Q14188 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 intact:EBI-752268|uniprotkb:Q13331|uniprotkb:Q14187|uniprotkb:Q6R754|uniprotkb:Q8WU88|uniprotkb:F8WAI2|uniprotkb:Q9UG28|uniprotkb:D3DNG1|uniprotkb:B7Z8L5|uniprotkb:B7Z8C8|uniprotkb:E9PFC3|ensembl:ENSP00000420616 psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:tfdp2_human(display_long)|uniprotkb:E2F dimerization partner 2(gene name synonym)|uniprotkb:TFDP2(gene name)|psi-mi:TFDP2(display_short)|uniprotkb:DP2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832656|imex:IM-21659-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity)|ddbj/embl/genbank:BC008348(identity) refseq:NP_001171609.1|refseq:NP_001171610.1|refseq:NP_006277.1|refseq:NP_001171612.1|refseq:NP_001171613.1|refseq:NP_001171611.1|refseq:XP_016862580.1|refseq:XP_016862585.1|refseq:XP_016862586.1|refseq:XP_016862587.1|refseq:XP_016862588.1|dip:DIP-294N|ensembl:ENSG00000114126(gene)|ensembl:ENST00000489671(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14188|rcsb pdb:1CF7|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9616222|reactome:R-HSA-9661069|uniprotkb:Q14188(identity)|entrezgene/locuslink:7029(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rogid:Y+N26+kjBjMVwXdL4AEp0Sc1rYY9606 intact-crc:94D10CA3FCC01EB5|rigid:gbKfrlEraT52VX+fQoSuXRgM9a8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75461 uniprotkb:Q8IWI9 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 intact:EBI-2815196|uniprotkb:E7ENI0|uniprotkb:F5H7K2|uniprotkb:Q9H9N7|uniprotkb:Q9H8R3|uniprotkb:Q9Y4E9|uniprotkb:Q9UG69|intact:EBI-11143500|intact:EBI-10969960|ensembl:ENSP00000219905|uniprotkb:B9EGR5 psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:mgap_human(display_long)|uniprotkb:MGA(gene name)|psi-mi:MGA(display_short)|uniprotkb:KIAA0518(gene name synonym)|uniprotkb:MAD5(gene name synonym)|uniprotkb:MAX dimerization protein 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832656|imex:IM-21659-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity)|ddbj/embl/genbank:BC008348(identity) refseq:NP_001074010.2|ensembl:ENSP00000219905|ensembl:ENST00000566586|ensembl:ENSP00000456141|ensembl:ENSG00000174197(gene)|ensembl:ENST00000219905(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR018186|interpro:IPR032060|interpro:IPR036638|interpro:IPR036960|interpro:IPR037935|mint:Q8IWI9|reactome:R-HSA-8953750|refseq:NP_001157745.1|dip:DIP-57615N|uniprotkb:Q8IWI9(identity)|entrezgene/locuslink:23269(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rogid:P4lo9EteCvikQQk5kyVkcobitLU9606 intact-crc:94D10CA3FCC01EB5|rigid:gbKfrlEraT52VX+fQoSuXRgM9a8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75461 uniprotkb:Q9NX08 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 intact:EBI-725694|uniprotkb:Q8WUR4|uniprotkb:Q9HC15|ensembl:ENSP00000370984 psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:comd8_human(display_long)|uniprotkb:COMMD8(gene name)|psi-mi:COMMD8(display_short)|uniprotkb:MDS022(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832656|imex:IM-21659-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity)|ddbj/embl/genbank:BC008348(identity) refseq:NP_060315.1|ensembl:ENSG00000169019(gene)|ensembl:ENST00000381571(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR017920|mint:Q9NX08|reactome:R-HSA-8951664|refseq:NP_001316597.1|uniprotkb:Q9NX08(identity)|entrezgene/locuslink:54951(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rogid:m3HKrdrtTRNJyCfMBLOZCaZRexg9606 intact-crc:94D10CA3FCC01EB5|rigid:gbKfrlEraT52VX+fQoSuXRgM9a8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75461 uniprotkb:Q9BQE3 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832656|imex:IM-21659-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity)|ddbj/embl/genbank:BC008348(identity) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1|uniprotkb:Q9BQE3(identity)|entrezgene/locuslink:84790(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:94D10CA3FCC01EB5|rigid:gbKfrlEraT52VX+fQoSuXRgM9a8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75461 uniprotkb:Q92769 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 intact:EBI-301821|uniprotkb:Q5SRI8|uniprotkb:Q5SZ86|uniprotkb:Q8NEH4|uniprotkb:B4DL58|ensembl:ENSP00000430432|uniprotkb:E1P561|uniprotkb:B3KRS5 psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:hdac2_human(display_long)|uniprotkb:HDAC2(gene name)|psi-mi:HDAC2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832656|imex:IM-21659-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity)|ddbj/embl/genbank:BC008348(identity) go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035094"(response to nicotine)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042220"(response to cocaine)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q92769|rcsb pdb:3MAX|rcsb pdb:4LXZ|rcsb pdb:4LY1|rcsb pdb:5IWG|rcsb pdb:5IX0|rcsb pdb:6G3O|rcsb pdb:6WBW|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000196591(gene)|ensembl:ENST00000519065(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|rcsb pdb:6WHN|rcsb pdb:6WHO|rcsb pdb:6WHQ|rcsb pdb:6WHZ|rcsb pdb:6WI3|rcsb pdb:6XDM|rcsb pdb:6XEB|rcsb pdb:6XEC|rcsb pdb:7KBG|rcsb pdb:7KBH|rcsb pdb:7LTG|rcsb pdb:7LTK|rcsb pdb:7LTL|reactome:R-HSA-193670|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9615017|reactome:R-HSA-9619665|reactome:R-HSA-9679191|reactome:R-HSA-983231|rcsb pdb:6WBZ|refseq:NP_001518.3|dip:DIP-24220N|refseq:XP_011534090.1|refseq:XP_016866288.1|uniprotkb:Q92769(identity)|entrezgene/locuslink:3066(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rogid:K4PpGz9E9/TrQZsgvrJuc+uYCn89606 intact-crc:94D10CA3FCC01EB5|rigid:gbKfrlEraT52VX+fQoSuXRgM9a8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75461 uniprotkb:P83916 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832656|imex:IM-21659-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity)|ddbj/embl/genbank:BC008348(identity) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|entrezgene/locuslink:10951(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 intact-crc:94D10CA3FCC01EB5|rigid:gbKfrlEraT52VX+fQoSuXRgM9a8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75461 uniprotkb:Q969R5 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832656|imex:IM-21659-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity)|ddbj/embl/genbank:BC008348(identity) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750|uniprotkb:Q969R5(identity)|entrezgene/locuslink:83746(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 intact-crc:94D10CA3FCC01EB5|rigid:gbKfrlEraT52VX+fQoSuXRgM9a8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75461 uniprotkb:P22531 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 intact:EBI-2556846|uniprotkb:Q5T9T4|uniprotkb:Q96RM2|ensembl:ENSP00000357739|ensembl:ENSP00000357740 psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:spr2e_human(display_long)|uniprotkb:Small proline-rich protein II(gene name synonym)|uniprotkb:SPRR2E(gene name)|psi-mi:SPRR2E(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832656|imex:IM-21659-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity)|ddbj/embl/genbank:BC008348(identity) refseq:NP_001019380.2|ensembl:ENSG00000203785(gene)|ensembl:ENST00000368750(transcript)|ensembl:ENST00000368751(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0031424"(keratinization)|interpro:IPR029142|mint:P22531|reactome:R-HSA-6809371|uniprotkb:P22531(identity)|entrezgene/locuslink:6704(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rogid:Pwemojva9RHkLb7mVmctpxenpf49606 intact-crc:94D10CA3FCC01EB5|rigid:gbKfrlEraT52VX+fQoSuXRgM9a8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75461 uniprotkb:Q5VZL5 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 intact:EBI-2514659|intact:EBI-28984130|ensembl:ENSP00000322915|uniprotkb:A0JP19|uniprotkb:O43308|uniprotkb:A0JP20|uniprotkb:Q5T5E2|uniprotkb:Q7L3Q4|uniprotkb:Q5T5E1|intact:EBI-2556245 psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:zmym4_human(display_long)|uniprotkb:ZMYM4(gene name)|psi-mi:ZMYM4(display_short)|uniprotkb:KIAA0425(gene name synonym)|uniprotkb:ZNF262(gene name synonym)|uniprotkb:Zinc finger protein 262(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832656|imex:IM-21659-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity)|ddbj/embl/genbank:BC008348(identity) ensembl:ENSG00000146463(gene)|ensembl:ENST00000314607(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022604"(regulation of cell morphogenesis)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR021893|refseq:XP_016858292.1|refseq:XP_016858293.1|refseq:XP_011540725.1|refseq:XP_011540727.1|refseq:NP_005086.2|ensembl:ENSP00000322915|refseq:XP_005271388.1|uniprotkb:Q5VZL5(identity)|entrezgene/locuslink:9202(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rogid:jc8YwR+37J3uD08cXiUnOA2hHEI9606 intact-crc:94D10CA3FCC01EB5|rigid:gbKfrlEraT52VX+fQoSuXRgM9a8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75461 uniprotkb:P61964 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832656|imex:IM-21659-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity)|ddbj/embl/genbank:BC008348(identity) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|entrezgene/locuslink:11091(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 intact-crc:94D10CA3FCC01EB5|rigid:gbKfrlEraT52VX+fQoSuXRgM9a8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75461 uniprotkb:P05090 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 intact:EBI-715495|uniprotkb:Q6IBG6|uniprotkb:B2R579|uniprotkb:D3DNW6|ensembl:ENSP00000345179 psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:apod_human(display_long)|uniprotkb:APOD(gene name)|psi-mi:APOD(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832656|imex:IM-21659-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity)|ddbj/embl/genbank:BC008348(identity) refseq:NP_001638.1|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030425"(dendrite)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048678"(response to axon injury)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0060588"(negative regulation of lipoprotein lipid oxidation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071638"(negative regulation of monocyte chemotactic protein-1 production)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:2000098"(negative regulation of smooth muscle cell-matrix adhesion)|go:"GO:2000405"(negative regulation of T cell migration)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR002969(Apolipoprotein D)|interpro:IPR012674(Calycin)|interpro:IPR022271|interpro:IPR022272|interpro:IPR026222|mint:P05090|rcsb pdb:2APD|rcsb pdb:2HZQ|rcsb pdb:2HZR|reactome:R-HSA-804914|reactome:R-HSA-9029569|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0015485"(cholesterol binding)|ensembl:ENSG00000189058(gene)|ensembl:ENST00000343267(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001525"(angiogenesis)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|uniprotkb:P05090(identity)|entrezgene/locuslink:347(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rogid:eD7+u5/ZQ5vntlwrq6itkhCxZJU9606 intact-crc:94D10CA3FCC01EB5|rigid:gbKfrlEraT52VX+fQoSuXRgM9a8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75461 uniprotkb:Q13185 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832656|imex:IM-21659-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity)|ddbj/embl/genbank:BC008348(identity) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 intact-crc:94D10CA3FCC01EB5|rigid:gbKfrlEraT52VX+fQoSuXRgM9a8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75461 uniprotkb:P61244 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832656|imex:IM-21659-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity)|ddbj/embl/genbank:BC008348(identity) refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750|uniprotkb:P61244(identity)|entrezgene/locuslink:4149(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rogid:I5d1d/zT353OsLios95yEITNoWU9606 intact-crc:94D10CA3FCC01EB5|rigid:gbKfrlEraT52VX+fQoSuXRgM9a8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75461 uniprotkb:Q9BYE7 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832656|imex:IM-21659-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity)|ddbj/embl/genbank:BC008348(identity) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 intact-crc:94D10CA3FCC01EB5|rigid:gbKfrlEraT52VX+fQoSuXRgM9a8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75461 uniprotkb:Q08188 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 intact:EBI-1050019|uniprotkb:A8K5N6|uniprotkb:Q32MM0|uniprotkb:O95933|uniprotkb:Q32ML9|uniprotkb:B2RCR6|uniprotkb:D3DVX1|ensembl:ENSP00000370867 psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:tgm3_human(display_long)|uniprotkb:Transglutaminase-3(gene name synonym)|uniprotkb:TGM3(gene name)|psi-mi:TGM3(display_short)|uniprotkb:Transglutaminase E(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832656|imex:IM-21659-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity)|ddbj/embl/genbank:BC008348(identity) refseq:NP_003236.3|ensembl:ENSG00000125780(gene)|ensembl:ENST00000381458(transcript)|go:"GO:0003810"(protein-glutamine gamma-glutamyltransferase activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031424"(keratinization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043163"(cell envelope organization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001102(Transglutaminase, N-terminal)|interpro:IPR002931(Transglutaminase-like)|interpro:IPR008958(Transglutaminase, C-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013808(Transglutaminase, conserved site)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR023608|interpro:IPR036238|interpro:IPR036985|interpro:IPR038765|mint:Q08188|rcsb pdb:1L9M|rcsb pdb:1L9N|rcsb pdb:1NUD|rcsb pdb:1NUF|rcsb pdb:1NUG|uniprotkb:Q08188(identity)|entrezgene/locuslink:7053(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rogid:5UuVUvhYOaQcLJQO2myrilPgFFw9606 intact-crc:94D10CA3FCC01EB5|rigid:gbKfrlEraT52VX+fQoSuXRgM9a8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75461 uniprotkb:P22528 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 intact:EBI-1058892|ensembl:ENSP00000306461|uniprotkb:B2R5H7|uniprotkb:P22529|uniprotkb:P22530|uniprotkb:Q5T524 psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:spr1b_human(display_long)|uniprotkb:SPRR1B(gene name)|psi-mi:SPRR1B(display_short)|uniprotkb:Small proline-rich protein IB(gene name synonym)|uniprotkb:14.9 kDa pancornulin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832656|imex:IM-21659-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity)|ddbj/embl/genbank:BC008348(identity) ensembl:ENSG00000169469(gene)|ensembl:ENST00000307098(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031424"(keratinization)|interpro:IPR003302("Cornifin (SPRR)")|mint:P22528|reactome:R-HSA-6809371|refseq:NP_003116.2|entrezgene/locuslink:6699(identity)|uniprotkb:P22528(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rogid:WU0vu+DHdIJm0x40HdcpAdJgdgo9606 intact-crc:94D10CA3FCC01EB5|rigid:gbKfrlEraT52VX+fQoSuXRgM9a8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75461 uniprotkb:P04745 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 intact:EBI-738586|uniprotkb:Q13763|uniprotkb:A6NJS5|uniprotkb:A8K8H6|uniprotkb:Q5T083 psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:amy1a_human(display_long)|uniprotkb:AMY1A(gene name)|psi-mi:AMY1A(display_short)|uniprotkb:AMY1(gene name synonym)|uniprotkb:1,4-alpha-D-glucan glucanohydrolase 1(gene name synonym)|uniprotkb:Salivary alpha-amylase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832656|imex:IM-21659-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity)|ddbj/embl/genbank:BC008348(identity) ensembl:ENST00000330330|ensembl:ENST00000370079|ensembl:ENST00000370080|ensembl:ENST00000370083|refseq:NP_001008219.1|refseq:NP_001008220.1|refseq:NP_001008222.1|refseq:NP_004029.2|interpro:IPR006048(Alpha-amylase, C-terminal all beta)|interpro:IPR006046(Glycoside hydrolase family 13)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|go:"GO:0004556"(alpha-amylase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0005975"(carbohydrate metabolic process)|rcsb pdb:1C8Q|rcsb pdb:1JXJ|rcsb pdb:1JXK|rcsb pdb:1MFU|rcsb pdb:1MFV|rcsb pdb:1NM9|rcsb pdb:1Q4N|rcsb pdb:1SMD|rcsb pdb:1XV8|rcsb pdb:1Z32|rcsb pdb:3BLK|rcsb pdb:3BLP|rcsb pdb:3DHP|refseq:XP_016856547.1|interpro:IPR031319|reactome:R-HSA-189085|go:"GO:0005615"(extracellular space)|go:"GO:0070062"(extracellular exosome)|refseq:XP_011539564.1|refseq:NP_001333709.1|ensembl:ENSG00000174876|ensembl:ENSG00000187733|ensembl:ENSG00000237763|ensembl:ENSP00000330484|ensembl:ENSP00000359096|ensembl:ENSP00000359097|ensembl:ENSP00000359100|go:"GO:0103025"|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|entrezgene/locuslink:277(identity)|entrezgene/locuslink:278(identity)|uniprotkb:P04745(identity) psi-mi:"MI:0469"(intact) - caution:This sequence has been withdrawn from Uniprot. figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rogid:Gwt64Wrt6IUZmCIxM3CXQxe7W509606 intact-crc:94D10CA3FCC01EB5|rigid:gbKfrlEraT52VX+fQoSuXRgM9a8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75461 uniprotkb:Q8WVV4 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 intact:EBI-2877727|ensembl:ENSP00000262753|uniprotkb:Q9H738|uniprotkb:Q9H744|uniprotkb:Q5H9F0|uniprotkb:Q8NG12|uniprotkb:Q5H9E9|uniprotkb:Q9H5Y2|uniprotkb:A8K2U5 psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:pof1b_human(display_long)|uniprotkb:POF1B(gene name)|psi-mi:POF1B(display_short)|uniprotkb:Premature ovarian failure protein 1B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832656|imex:IM-21659-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity)|ddbj/embl/genbank:BC008348(identity) ensembl:ENST00000262753(transcript)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005884"(actin filament)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030057"(desmosome)|go:"GO:0051015"(actin filament binding)|go:"GO:0070830"(bicellular tight junction assembly)|interpro:IPR026186|mint:Q8WVV4|rcsb pdb:3BH9|ensembl:ENSG00000124429(gene)|refseq:NP_001294869.1|refseq:NP_079197.3|ensembl:ENSP00000262753|ensembl:ENST00000373145|ensembl:ENSP00000362238|uniprotkb:Q8WVV4(identity)|entrezgene/locuslink:79983(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rogid:rigOH+ulgEPejDWfjfmcn2M2B2M9606 intact-crc:94D10CA3FCC01EB5|rigid:gbKfrlEraT52VX+fQoSuXRgM9a8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75461 uniprotkb:P31949 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 intact:EBI-701862|uniprotkb:Q5VTK0|ensembl:ENSP00000271638 psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:s10ab_human(display_long)|uniprotkb:S100 calcium-binding protein A11(gene name synonym)|uniprotkb:Calgizzarin(gene name synonym)|uniprotkb:Metastatic lymph node gene 70 protein(gene name synonym)|uniprotkb:S100A11(gene name)|psi-mi:S100A11(display_short)|uniprotkb:MLN70(gene name synonym)|uniprotkb:S100C(gene name synonym)|uniprotkb:Protein S100-C(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832656|imex:IM-21659-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity)|ddbj/embl/genbank:BC008348(identity) refseq:NP_005611.1|ensembl:ENSG00000163191(gene)|ensembl:ENST00000271638(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007165"(signal transduction)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028482|mint:P31949|rcsb pdb:1V4Z|rcsb pdb:1V50|rcsb pdb:2LUC|reactome:R-HSA-6798695|uniprotkb:P31949(identity)|entrezgene/locuslink:6282(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rogid:BG1iIxIcMpumVbd2yTJwB5gy4VU9606 intact-crc:94D10CA3FCC01EB5|rigid:gbKfrlEraT52VX+fQoSuXRgM9a8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75461 uniprotkb:Q99496 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832656|imex:IM-21659-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity)|ddbj/embl/genbank:BC008348(identity) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|entrezgene/locuslink:6045(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 intact-crc:94D10CA3FCC01EB5|rigid:gbKfrlEraT52VX+fQoSuXRgM9a8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75461 uniprotkb:Q9H0A8 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 intact:EBI-1550064|uniprotkb:Q7L637|uniprotkb:Q9NX43|uniprotkb:B2RBN4|uniprotkb:H3BUL2|ensembl:ENSP00000267935|ensembl:ENSP00000433662 psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:comd4_human(display_long)|uniprotkb:COMMD4(gene name)|psi-mi:COMMD4(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832656|imex:IM-21659-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity)|ddbj/embl/genbank:BC008348(identity) refseq:NP_001271306.1|refseq:NP_060298.2|refseq:NP_001271307.1|ensembl:ENSG00000140365(gene)|ensembl:ENST00000267935(transcript)|ensembl:ENST00000480484(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR017920|interpro:IPR037356|reactome:R-HSA-8951664|uniprotkb:Q9H0A8(identity)|entrezgene/locuslink:54939(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rogid:v1pkDNc18f7sZM/89Gv0bho9GN89606 intact-crc:94D10CA3FCC01EB5|rigid:gbKfrlEraT52VX+fQoSuXRgM9a8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75461 uniprotkb:Q14186 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832656|imex:IM-21659-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity)|ddbj/embl/genbank:BC008348(identity) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|entrezgene/locuslink:7027(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 intact-crc:94D10CA3FCC01EB5|rigid:gbKfrlEraT52VX+fQoSuXRgM9a8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75461 uniprotkb:Q06587 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832656|imex:IM-21659-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity)|ddbj/embl/genbank:BC008348(identity) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 intact-crc:94D10CA3FCC01EB5|rigid:gbKfrlEraT52VX+fQoSuXRgM9a8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75461 uniprotkb:P62891 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 intact:EBI-8830744|uniprotkb:P02404|uniprotkb:Q9BYF2|uniprotkb:P39025|ensembl:ENSP00000355315 psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:rl39_human(display_long)|uniprotkb:RPL39(gene name)|psi-mi:RPL39(display_short)|uniprotkb:Large ribosomal subunit protein eL39(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832656|imex:IM-21659-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity)|ddbj/embl/genbank:BC008348(identity) refseq:NP_000991.1|rcsb pdb:4V6X|ensembl:ENSG00000198918(gene)|ensembl:ENST00000361575(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000077(Ribosomal protein L39e)|interpro:IPR020083|interpro:IPR023626|rcsb pdb:4UG0|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|uniprotkb:P62891(identity)|entrezgene/locuslink:6170(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rogid:AZus2dxwJsTxAOwnJ93E2yhasbo9606 intact-crc:94D10CA3FCC01EB5|rigid:gbKfrlEraT52VX+fQoSuXRgM9a8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75530 uniprotkb:Q16576 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832817|imex:IM-21659-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:O75530(identity)|ddbj/embl/genbank:BC068995(identity)|entrezgene/locuslink:8726(identity) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|entrezgene/locuslink:5931(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 intact-crc:96521ED71918747E|rigid:CZoqS4NEroXduqDg1MVzEK/OaPI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75530 uniprotkb:Q15910 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832817|imex:IM-21659-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:O75530(identity)|ddbj/embl/genbank:BC068995(identity)|entrezgene/locuslink:8726(identity) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N|uniprotkb:Q15910(identity)|entrezgene/locuslink:2146(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 intact-crc:96521ED71918747E|rigid:CZoqS4NEroXduqDg1MVzEK/OaPI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75530 uniprotkb:Q9Y483 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 intact:EBI-725816|uniprotkb:A6NGQ9|uniprotkb:Q9UES9|uniprotkb:Q9UP40|uniprotkb:A8K2Q3|uniprotkb:B1AKT5|intact:EBI-11028207|uniprotkb:Q96G26|uniprotkb:B1AKT6|ensembl:ENSP00000359321 psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:mtf2_human(display_long)|uniprotkb:PCL2(gene name synonym)|uniprotkb:Metal-response element DNA-binding protein M96(gene name synonym)|uniprotkb:Metal regulatory transcription factor 2(gene name synonym)|uniprotkb:Polycomb-like protein 2(gene name synonym)|uniprotkb:MTF2(gene name)|psi-mi:MTF2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832817|imex:IM-21659-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:O75530(identity)|ddbj/embl/genbank:BC068995(identity)|entrezgene/locuslink:8726(identity) refseq:NP_001157863.1|refseq:NP_001157865.1|refseq:NP_031384.1|refseq:XP_011539318.1|refseq:XP_016856165.1|ensembl:ENSG00000143033(gene)|ensembl:ENST00000370298(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042015|mint:Q9Y483|rcsb pdb:5XFR|reactome:R-HSA-212300|interpro:IPR042014|refseq:NP_001157864.1|uniprotkb:Q9Y483(identity)|entrezgene/locuslink:22823(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 rogid:Im8E6U/OPb8AEir43AUUDlU6F2o9606 intact-crc:96521ED71918747E|rigid:CZoqS4NEroXduqDg1MVzEK/OaPI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75530 uniprotkb:P78371 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300 psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832817|imex:IM-21659-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:O75530(identity)|ddbj/embl/genbank:BC068995(identity)|entrezgene/locuslink:8726(identity) refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695|uniprotkb:P78371(identity)|entrezgene/locuslink:10576(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606 intact-crc:96521ED71918747E|rigid:CZoqS4NEroXduqDg1MVzEK/OaPI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75530 uniprotkb:P31151 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 intact:EBI-357520|uniprotkb:Q6FGE3|uniprotkb:Q5SY67|uniprotkb:Q9H1E2|ensembl:ENSP00000357711|ensembl:ENSP00000357712 psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:s10a7_human(display_long)|uniprotkb:S100A7(gene name)|psi-mi:S100A7(display_short)|uniprotkb:PSOR1(gene name synonym)|uniprotkb:S100A7C(gene name synonym)|uniprotkb:S100 calcium-binding protein A7(gene name synonym)|uniprotkb:Psoriasin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832817|imex:IM-21659-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:O75530(identity)|ddbj/embl/genbank:BC068995(identity)|entrezgene/locuslink:8726(identity) ensembl:ENSG00000143556(gene)|ensembl:ENST00000368722(transcript)|ensembl:ENST00000368723(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001525"(angiogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008544"(epidermis development)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045087"(innate immune response)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051238"(sequestering of metal ion)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071624"(positive regulation of granulocyte chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028477|interpro:IPR034325|mint:P31151|rcsb pdb:1PSR|rcsb pdb:2PSR|rcsb pdb:2WND|rcsb pdb:2WOR|rcsb pdb:2WOS|rcsb pdb:3PSR|rcsb pdb:4AQJ|reactome:R-HSA-6798695|reactome:R-HSA-6799990|refseq:NP_002954.2|uniprotkb:P31151(identity)|entrezgene/locuslink:6278(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 rogid:/v8+XQ7rCMTYzq9k/KqjcSm/G0A9606 intact-crc:96521ED71918747E|rigid:CZoqS4NEroXduqDg1MVzEK/OaPI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75530 uniprotkb:P40227 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2 psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832817|imex:IM-21659-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:O75530(identity)|ddbj/embl/genbank:BC068995(identity)|entrezgene/locuslink:8726(identity) refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N|uniprotkb:P40227(identity)|entrezgene/locuslink:908(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606 intact-crc:96521ED71918747E|rigid:CZoqS4NEroXduqDg1MVzEK/OaPI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75530 uniprotkb:Q96JN0 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 intact:EBI-746045|uniprotkb:Q9H945|uniprotkb:Q9Y457|ensembl:ENSP00000348298|ensembl:ENSP00000360138|ensembl:ENSP00000360144|ensembl:ENSP00000501560|ensembl:ENSP00000501639|ensembl:ENSP00000502633|intact:EBI-8833163|uniprotkb:D3DR47|uniprotkb:Q5VW16|uniprotkb:Q7Z723|uniprotkb:Q86T32|uniprotkb:Q86T33|uniprotkb:Q8N3L6|uniprotkb:Q8N655 psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:lcor_human(display_long)|uniprotkb:LCOR(gene name)|psi-mi:LCOR(display_short)|uniprotkb:C10orf12(gene name synonym)|uniprotkb:KIAA1795(gene name synonym)|uniprotkb:MLR2(gene name synonym)|uniprotkb:Mblk1-related protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832817|imex:IM-21659-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:O75530(identity)|ddbj/embl/genbank:BC068995(identity)|entrezgene/locuslink:8726(identity) ensembl:ENSG00000196233(gene)|ensembl:ENST00000356016(transcript)|ensembl:ENST00000371097(transcript)|ensembl:ENST00000371103(transcript)|ensembl:ENST00000675471(transcript)|ensembl:ENST00000675537(transcript)|ensembl:ENST00000675971(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|mint:Q96JN0|rcsb pdb:2COB|refseq:NP_001164236.1|refseq:NP_001164237.1|refseq:NP_115816.2|refseq:XP_016872275.1|refseq:XP_016872276.1|refseq:XP_016872277.1|refseq:NP_001333445.1|uniprotkb:Q8N655(identity)|entrezgene/locuslink:26148(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 rogid:cOnk6EDDff86yaG1uG+dxEQ1Z689606 intact-crc:96521ED71918747E|rigid:CZoqS4NEroXduqDg1MVzEK/OaPI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75530 uniprotkb:Q92833 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 intact:EBI-1222720|uniprotkb:Q5U5L5|uniprotkb:A8K9Z6|uniprotkb:B7Z5S5|uniprotkb:Q86X63|uniprotkb:B7Z8L0|ensembl:ENSP00000341280 psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:jard2_human(display_long)|uniprotkb:JARID2(gene name)|psi-mi:JARID2(display_short)|uniprotkb:JMJ(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832817|imex:IM-21659-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:O75530(identity)|ddbj/embl/genbank:BC068995(identity)|entrezgene/locuslink:8726(identity) refseq:NP_004964.2|refseq:NP_001253969.1|refseq:XP_005249146.1|refseq:XP_016866323.1|refseq:XP_016866324.1|dip:DIP-45494N|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR036431|mint:Q92833|rcsb pdb:5HYN|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000008083(gene)|ensembl:ENST00000341776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007417"(central nervous system development)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0034721"(histone H3-K4 demethylation, trimethyl-H3-K4-specific)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|uniprotkb:Q92833(identity)|entrezgene/locuslink:3720(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 rogid:G/oMY7WdV7UyQwfT4MOZyET2fS89606 intact-crc:96521ED71918747E|rigid:CZoqS4NEroXduqDg1MVzEK/OaPI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75530 uniprotkb:P49368 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688 psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832817|imex:IM-21659-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:O75530(identity)|ddbj/embl/genbank:BC068995(identity)|entrezgene/locuslink:8726(identity) refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N|uniprotkb:P49368(identity)|entrezgene/locuslink:7203(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606 intact-crc:96521ED71918747E|rigid:CZoqS4NEroXduqDg1MVzEK/OaPI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75530 uniprotkb:Q99832 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091 psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832817|imex:IM-21659-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:O75530(identity)|ddbj/embl/genbank:BC068995(identity)|entrezgene/locuslink:8726(identity) dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|uniprotkb:Q99832(identity)|entrezgene/locuslink:10574(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606 intact-crc:96521ED71918747E|rigid:CZoqS4NEroXduqDg1MVzEK/OaPI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75530 uniprotkb:O43189 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 intact:EBI-530034|uniprotkb:B1AZX2|uniprotkb:B1AZX3|uniprotkb:O60929|uniprotkb:Q96KM7|uniprotkb:Q5SU07|uniprotkb:Q5SU08|ensembl:ENSP00000363640|ensembl:ENSP00000391901|ensembl:ENSP00000407295 psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:phf1_human(display_long)|uniprotkb:PCL1(gene name synonym)|uniprotkb:Polycomb-like protein 1(gene name synonym)|uniprotkb:PHF1(gene name)|psi-mi:PHF1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832817|imex:IM-21659-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:O75530(identity)|ddbj/embl/genbank:BC068995(identity)|entrezgene/locuslink:8726(identity) refseq:XP_011512964.1|refseq:NP_002627.1|refseq:NP_077084.1|ensembl:ENSG00000112511(gene)|ensembl:ENSG00000225553(gene)|ensembl:ENST00000374516(transcript)|ensembl:ENST00000427869(transcript)|ensembl:ENST00000454914(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR031202|interpro:IPR040477|mint:O43189|rcsb pdb:2E5P|rcsb pdb:2M0O|rcsb pdb:4HCZ|rcsb pdb:5XFN|rcsb pdb:5XFO|rcsb pdb:5XFP|rcsb pdb:6WAT|rcsb pdb:6WAV|reactome:R-HSA-212300|dip:DIP-34001N|uniprotkb:O43189(identity)|entrezgene/locuslink:5252(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 rogid:8n8g2LqzuOQb8cFC7tE1j/xBvkI9606 intact-crc:96521ED71918747E|rigid:CZoqS4NEroXduqDg1MVzEK/OaPI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75530 uniprotkb:A6NHQ4 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 intact:EBI-8831125|ensembl:ENSP00000483859|ensembl:ENSP00000484710 psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:epop_human(display_long)|uniprotkb:EPOP(gene name)|psi-mi:EPOP(display_short)|uniprotkb:C17orf96(gene name synonym)|uniprotkb:PRR28(gene name synonym)|uniprotkb:Proline-rich protein 28(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832817|imex:IM-21659-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:O75530(identity)|ddbj/embl/genbank:BC068995(identity)|entrezgene/locuslink:8726(identity) refseq:NP_001124149.1|ensembl:ENSG00000273604(gene)|ensembl:ENST00000613024(transcript)|ensembl:ENST00000621654(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005694"(chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0070449"(elongin complex)|interpro:IPR027971|mint:A6NHQ4|ensembl:ENSG00000277303(gene)|uniprotkb:A6NHQ4(identity)|entrezgene/locuslink:100170841(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 rogid:xxrapCjRxgY22pLac2F4zSS2bvk9606 intact-crc:96521ED71918747E|rigid:CZoqS4NEroXduqDg1MVzEK/OaPI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75530 uniprotkb:Q09028 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832817|imex:IM-21659-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:O75530(identity)|ddbj/embl/genbank:BC068995(identity)|entrezgene/locuslink:8726(identity) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|entrezgene/locuslink:5928(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 intact-crc:96521ED71918747E|rigid:CZoqS4NEroXduqDg1MVzEK/OaPI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75530 uniprotkb:Q5T6S3 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 intact:EBI-2339674|uniprotkb:Q6N038|uniprotkb:Q32NF2|uniprotkb:Q8TBL6|uniprotkb:Q5T6S4|uniprotkb:Q9UFS9|ensembl:ENSP00000363003 psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:phf19_human(display_long)|uniprotkb:PHF19(gene name)|psi-mi:PHF19(display_short)|uniprotkb:PCL3(gene name synonym)|uniprotkb:Polycomb-like protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832817|imex:IM-21659-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:O75530(identity)|ddbj/embl/genbank:BC068995(identity)|entrezgene/locuslink:8726(identity) refseq:XP_011516811.1|refseq:NP_001009936.1|refseq:NP_056466.1|refseq:NP_001273769.1|refseq:NP_001273772.1|refseq:XP_005251963.1|refseq:XP_016870101.1|ensembl:ENSG00000119403(gene)|ensembl:ENST00000373896(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042017|mint:Q5T6S3|rcsb pdb:2E5Q|rcsb pdb:4BD3|rcsb pdb:6NQ3|rcsb pdb:6WAU|reactome:R-HSA-212300|uniprotkb:Q5T6S3(identity)|entrezgene/locuslink:26147(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 rogid:K4sKpUT1htSiigJaEoGyDjvkWqc9606 intact-crc:96521ED71918747E|rigid:CZoqS4NEroXduqDg1MVzEK/OaPI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75530 uniprotkb:Q9BQE3 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832817|imex:IM-21659-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:O75530(identity)|ddbj/embl/genbank:BC068995(identity)|entrezgene/locuslink:8726(identity) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1|uniprotkb:Q9BQE3(identity)|entrezgene/locuslink:84790(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:96521ED71918747E|rigid:CZoqS4NEroXduqDg1MVzEK/OaPI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75530 uniprotkb:Q15022 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832817|imex:IM-21659-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:O75530(identity)|ddbj/embl/genbank:BC068995(identity)|entrezgene/locuslink:8726(identity) dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:Q15022(identity)|entrezgene/locuslink:23512(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 intact-crc:96521ED71918747E|rigid:CZoqS4NEroXduqDg1MVzEK/OaPI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75530 uniprotkb:Q92800 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 intact:EBI-8830732|uniprotkb:B4E3R7|uniprotkb:O43287|uniprotkb:A6NCH6|uniprotkb:Q14459|uniprotkb:Q53XP3|uniprotkb:B4DSS2|uniprotkb:B4DIJ1|uniprotkb:B4DIZ7|ensembl:ENSP00000404658|ensembl:ENSP00000466924 psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:ezh1_human(display_long)|uniprotkb:ENX-2(gene name synonym)|uniprotkb:Enhancer of zeste homolog 1(gene name synonym)|uniprotkb:KIAA0388(gene name synonym)|uniprotkb:EZH1(gene name)|psi-mi:EZH1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832817|imex:IM-21659-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:O75530(identity)|ddbj/embl/genbank:BC068995(identity)|entrezgene/locuslink:8726(identity) refseq:NP_001308008.1|refseq:NP_001308010.1|refseq:NP_001308011.1|refseq:NP_001982.2|dip:DIP-58580N|ensembl:ENSG00000108799(gene)|ensembl:ENST00000428826(transcript)|ensembl:ENST00000592743(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0021766"(hippocampus development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0031507"(heterochromatin assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR021654|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR032926|interpro:IPR041343|interpro:IPR041355|interpro:IPR044438|mint:Q92800|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|uniprotkb:Q92800(identity)|entrezgene/locuslink:2145(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 rogid:qp3eqBCgiaoA6VSSyqpW1d9YKN49606 intact-crc:96521ED71918747E|rigid:CZoqS4NEroXduqDg1MVzEK/OaPI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75530 uniprotkb:Q6ZN18 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 intact:EBI-743256|ensembl:ENSP00000381840|uniprotkb:Q59FS5|uniprotkb:Q6ZN62|uniprotkb:Q96BG3 psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:aebp2_human(display_long)|uniprotkb:Adipocyte enhancer-binding protein 2(gene name synonym)|uniprotkb:AEBP2(gene name)|psi-mi:AEBP2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832817|imex:IM-21659-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:O75530(identity)|ddbj/embl/genbank:BC068995(identity)|entrezgene/locuslink:8726(identity) ensembl:ENSG00000139154(gene)|interpro:IPR036236|ensembl:ENST00000398864(transcript)|go:"GO:0000785"(chromatin)|mint:Q6ZN18|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001107648.1|refseq:NP_694939.2|rcsb pdb:5WAI|rcsb pdb:5Y0U|rcsb pdb:5Y1U|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|reactome:R-HSA-3214841|refseq:NP_001253972.1|dip:DIP-58581N|uniprotkb:Q6ZN18(identity)|entrezgene/locuslink:121536(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 rogid:mOY+NOTaqJlXjW8v6D3YPnfnfBU9606 intact-crc:96521ED71918747E|rigid:CZoqS4NEroXduqDg1MVzEK/OaPI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96KQ7 uniprotkb:Q9H582 intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957 intact:EBI-2560435|uniprotkb:Q7LG67|uniprotkb:Q5TCC0|uniprotkb:Q6PI06|uniprotkb:Q9ULJ9|uniprotkb:A2RU71|uniprotkb:Q2TAM0|uniprotkb:Q6P446|uniprotkb:Q6BEP7|ensembl:ENSP00000337008|ensembl:ENSP00000359469 psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym) psi-mi:zn644_human(display_long)|uniprotkb:ZNF644(gene name)|psi-mi:ZNF644(display_short)|uniprotkb:KIAA1221(gene name synonym)|uniprotkb:ZEP2(gene name synonym)|uniprotkb:Zinc finger motif enhancer-binding protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832899|imex:IM-21659-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N|uniprotkb:Q96KQ7(identity)|entrezgene/locuslink:10919(identity)|ddbj/embl/genbank:BC002686(identity) refseq:NP_057704.2|refseq:NP_115562.3|refseq:NP_958357.1|refseq:XP_016857977.1|refseq:XP_016857978.1|refseq:XP_016857979.1|refseq:XP_016857980.1|refseq:XP_016857981.1|refseq:XP_016857982.1|refseq:XP_016857983.1|ensembl:ENSG00000122482(gene)|ensembl:ENST00000337393(transcript)|ensembl:ENST00000370440(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9H582|uniprotkb:Q9H582(identity)|entrezgene/locuslink:84146(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606 rogid:16MjfkV6aoDArzVV5Qi0K2HI2lg9606 intact-crc:DF5A0BA9527327D9|rigid:oWWJg7mMoNQjDoC06tdFKt7VzZY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96KQ7 uniprotkb:Q9GZZ8 intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957 intact:EBI-3623441|ensembl:ENSP00000257867 psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym) psi-mi:lacrt_human(display_long)|uniprotkb:LACRT(gene name)|psi-mi:LACRT(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832899|imex:IM-21659-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N|uniprotkb:Q96KQ7(identity)|entrezgene/locuslink:10919(identity)|ddbj/embl/genbank:BC002686(identity) refseq:NP_150593.1|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0060054"(positive regulation of epithelial cell proliferation involved in wound healing)|go:"GO:0070075"(tear secretion)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|interpro:IPR033530|interpro:IPR043557|ensembl:ENSG00000135413(gene)|ensembl:ENST00000257867(transcript)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006473"(protein acetylation)|go:"GO:0008083"(growth factor activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030141"(secretory granule)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0033173"(calcineurin-NFAT signaling cascade)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043237"(laminin-1 binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050850"(positive regulation of calcium-mediated signaling)|uniprotkb:Q9GZZ8(identity)|entrezgene/locuslink:90070(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606 rogid:pPe6jkneU4pZBt36lcsMn2XLbcg9606 intact-crc:DF5A0BA9527327D9|rigid:oWWJg7mMoNQjDoC06tdFKt7VzZY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96KQ7 uniprotkb:Q99832 intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957 intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091 psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym) psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832899|imex:IM-21659-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N|uniprotkb:Q96KQ7(identity)|entrezgene/locuslink:10919(identity)|ddbj/embl/genbank:BC002686(identity) dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|uniprotkb:Q99832(identity)|entrezgene/locuslink:10574(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606 rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606 intact-crc:DF5A0BA9527327D9|rigid:oWWJg7mMoNQjDoC06tdFKt7VzZY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96KQ7 uniprotkb:P49368 intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957 intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688 psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym) psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832899|imex:IM-21659-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N|uniprotkb:Q96KQ7(identity)|entrezgene/locuslink:10919(identity)|ddbj/embl/genbank:BC002686(identity) refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N|uniprotkb:P49368(identity)|entrezgene/locuslink:7203(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606 rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606 intact-crc:DF5A0BA9527327D9|rigid:oWWJg7mMoNQjDoC06tdFKt7VzZY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96KQ7 uniprotkb:P17987 intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957 intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334 psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym) psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832899|imex:IM-21659-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N|uniprotkb:Q96KQ7(identity)|entrezgene/locuslink:10919(identity)|ddbj/embl/genbank:BC002686(identity) refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N|uniprotkb:P17987(identity)|entrezgene/locuslink:6950(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606 rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606 intact-crc:DF5A0BA9527327D9|rigid:oWWJg7mMoNQjDoC06tdFKt7VzZY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96KQ7 uniprotkb:Q9H9B1 intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957 intact:EBI-766087|uniprotkb:Q8TCN7|uniprotkb:Q96F53|uniprotkb:Q96JF1|uniprotkb:Q96KH4|uniprotkb:B1AQ58|uniprotkb:B1AQ59|uniprotkb:Q86X08|ensembl:ENSP00000417980 psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym) psi-mi:ehmt1_human(display_long)|uniprotkb:KMT1D(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 5(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 1(gene name synonym)|uniprotkb:G9a-like protein 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1D(gene name synonym)|uniprotkb:EHMT1(gene name)|psi-mi:EHMT1(display_short)|uniprotkb:EUHMTASE1(gene name synonym)|uniprotkb:KIAA1876(gene name synonym)|uniprotkb:GLP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832899|imex:IM-21659-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N|uniprotkb:Q96KQ7(identity)|entrezgene/locuslink:10919(identity)|ddbj/embl/genbank:BC002686(identity) refseq:NP_001138999.1|refseq:NP_079033.4|ensembl:ENST00000371394|ensembl:ENSP00000485945|ensembl:ENSP00000417980|ensembl:ENST00000462484|ensembl:ENSP00000417328|dip:DIP-34585N|ensembl:ENSG00000181090(gene)|ensembl:ENST00000460843(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016604"(nuclear body)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038035|interpro:IPR043550|mint:Q9H9B1|rcsb pdb:2IGQ|rcsb pdb:2RFI|rcsb pdb:3B7B|rcsb pdb:3B95|rcsb pdb:3FPD|rcsb pdb:3HNA|rcsb pdb:3MO0|rcsb pdb:3MO2|rcsb pdb:3MO5|rcsb pdb:3SW9|rcsb pdb:3SWC|rcsb pdb:4I51|rcsb pdb:5TTG|rcsb pdb:5TUZ|rcsb pdb:5V9J|rcsb pdb:5VSD|rcsb pdb:5VSF|rcsb pdb:6BY9|rcsb pdb:6MBO|rcsb pdb:6MBP|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-6804760|reactome:R-HSA-8853884|reactome:R-HSA-8953750|uniprotkb:Q9H9B1(identity)|entrezgene/locuslink:79813(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606 rogid:4L6QOGSsRPi8hDjS2/BYShjpnf89606 intact-crc:DF5A0BA9527327D9|rigid:oWWJg7mMoNQjDoC06tdFKt7VzZY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96KQ7 uniprotkb:O95785 intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957 intact:EBI-1387294|uniprotkb:B7ZM82|uniprotkb:Q4G0E0|uniprotkb:Q6P6B0|uniprotkb:Q6ZN24|uniprotkb:Q7LDY6|uniprotkb:Q7LDZ1|uniprotkb:Q96IG5|uniprotkb:Q96SQ6|uniprotkb:Q9BUR8|uniprotkb:Q9NPT1|intact:EBI-10967552|uniprotkb:B3KVH1|uniprotkb:M0QY21 psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym) psi-mi:wiz_human(display_long)|uniprotkb:WIZ(gene name)|psi-mi:WIZ(display_short)|uniprotkb:ZNF803(gene name synonym)|uniprotkb:Widely-interspaced zinc finger-containing protein(gene name synonym)|uniprotkb:Zinc finger protein 803(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832899|imex:IM-21659-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N|uniprotkb:Q96KQ7(identity)|entrezgene/locuslink:10919(identity)|ddbj/embl/genbank:BC002686(identity) refseq:NP_067064.2|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001317324.1|interpro:IPR036236|mint:O95785|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|go:"GO:0030496"(midbody)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990226"(histone methyltransferase binding)|uniprotkb:O95785(identity)|entrezgene/locuslink:58525(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606 rogid:FMQwuMDlEC/Zdsnayyl7kpQSmyg9606 intact-crc:DF5A0BA9527327D9|rigid:oWWJg7mMoNQjDoC06tdFKt7VzZY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96KQ7 uniprotkb:Q13263 intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957 intact:EBI-78139|uniprotkb:O00677|ensembl:ENSP00000253024|uniprotkb:Q7Z632|uniprotkb:Q93040|uniprotkb:Q96IM1 psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym) psi-mi:tif1b_human(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832899|imex:IM-21659-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N|uniprotkb:Q96KQ7(identity)|entrezgene/locuslink:10919(identity)|ddbj/embl/genbank:BC002686(identity) ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6QAJ|rcsb pdb:6QU1|reactome:R-HSA-212436|reactome:R-HSA-3899300|reactome:R-HSA-9609690|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q13263|rcsb pdb:1FP0|rcsb pdb:2RO1|rcsb pdb:2YVR|rcsb pdb:6H3A|rcsb pdb:6I9H|refseq:NP_005753.1|dip:DIP-30891N|uniprotkb:Q13263(identity)|entrezgene/locuslink:10155(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606 rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606 intact-crc:DF5A0BA9527327D9|rigid:oWWJg7mMoNQjDoC06tdFKt7VzZY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96KQ7 uniprotkb:Q14257 intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957 intact:EBI-356710|uniprotkb:A8MTG6|uniprotkb:Q53XN8|ensembl:ENSP00000378349|uniprotkb:F8WCY5 psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym) psi-mi:rcn2_human(display_long)|uniprotkb:RCN2(gene name)|psi-mi:RCN2(display_short)|uniprotkb:ERC55(gene name synonym)|uniprotkb:Calcium-binding protein ERC-55(gene name synonym)|uniprotkb:E6-binding protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832899|imex:IM-21659-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N|uniprotkb:Q96KQ7(identity)|entrezgene/locuslink:10919(identity)|ddbj/embl/genbank:BC002686(identity) refseq:NP_002893.1|ensembl:ENST00000394885(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|ensembl:ENSG00000117906(gene)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q14257|refseq:NP_001258766.1|uniprotkb:Q14257(identity)|entrezgene/locuslink:5955(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606 rogid:99ru/7eYUvZ5xdb+x4inbib3PP89606 intact-crc:DF5A0BA9527327D9|rigid:oWWJg7mMoNQjDoC06tdFKt7VzZY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96KQ7 uniprotkb:P61964 intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym) psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832899|imex:IM-21659-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N|uniprotkb:Q96KQ7(identity)|entrezgene/locuslink:10919(identity)|ddbj/embl/genbank:BC002686(identity) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|entrezgene/locuslink:11091(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 intact-crc:DF5A0BA9527327D9|rigid:oWWJg7mMoNQjDoC06tdFKt7VzZY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96KQ7 uniprotkb:Q9Y265 intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957 intact:EBI-353675|uniprotkb:P82276|uniprotkb:Q1KMR0|uniprotkb:Q53HK5|uniprotkb:Q53HL7|uniprotkb:Q53Y27|uniprotkb:Q9BSX9|uniprotkb:B2R5S0|ensembl:ENSP00000318297|ensembl:ENSP00000494621 psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym) psi-mi:ruvb1_human(display_long)|uniprotkb:RUVBL1(gene name)|psi-mi:RUVBL1(display_short)|uniprotkb:NMP238(gene name synonym)|uniprotkb:TIP49(gene name synonym)|uniprotkb:TIP49A(gene name synonym)|uniprotkb:49 kDa TATA box-binding protein-interacting protein(gene name synonym)|uniprotkb:TIP49a(gene name synonym)|uniprotkb:Pontin 52(gene name synonym)|uniprotkb:Nuclear matrix protein 238(gene name synonym)|uniprotkb:54 kDa erythrocyte cytosolic protein(gene name synonym)|uniprotkb:INO80H(gene name synonym)|uniprotkb:TIP60-associated protein 54-alpha(gene name synonym)|uniprotkb:INO80 complex subunit H(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832899|imex:IM-21659-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N|uniprotkb:Q96KQ7(identity)|entrezgene/locuslink:10919(identity)|ddbj/embl/genbank:BC002686(identity) refseq:NP_003698.1|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016573"(histone acetylation)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037938|interpro:IPR041048|mint:Q9Y265|rcsb pdb:2C9O|rcsb pdb:2XSZ|rcsb pdb:5OAF|rcsb pdb:6FO1|rcsb pdb:6HTS|rcsb pdb:6IGM|rcsb pdb:6K0R|rcsb pdb:6QI8|rcsb pdb:6QI9|rcsb pdb:7AHO|reactome:R-HSA-171319|reactome:R-HSA-201722|reactome:R-HSA-3214847|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5696394|reactome:R-HSA-606279|ensembl:ENSG00000175792(gene)|ensembl:ENSG00000284901(gene)|ensembl:ENST00000322623(transcript)|ensembl:ENST00000643444(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|refseq:NP_001306013.1|dip:DIP-29937N|uniprotkb:Q9Y265(identity)|entrezgene/locuslink:8607(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606 rogid:+FA/xQTUldQoWGRgad9U8vZpTHw9606 intact-crc:DF5A0BA9527327D9|rigid:oWWJg7mMoNQjDoC06tdFKt7VzZY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96KQ7 uniprotkb:O95831 intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957 intact:EBI-356440|uniprotkb:Q5JUZ7|uniprotkb:Q6I9X6|uniprotkb:Q9Y3I3|uniprotkb:Q9Y3I4|uniprotkb:A4QPB4|uniprotkb:B1ALN1|uniprotkb:B2RB08|intact:EBI-2561858|uniprotkb:D3DTE9|uniprotkb:Q1L6K6|uniprotkb:Q2QKE4|uniprotkb:Q1L6K4|ensembl:ENSP00000287295|uniprotkb:E9PRR0 psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym) psi-mi:aifm1_human(display_long)|uniprotkb:AIFM1(gene name)|psi-mi:AIFM1(display_short)|uniprotkb:AIF(gene name synonym)|uniprotkb:PDCD8(gene name synonym)|uniprotkb:Programmed cell death protein 8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832899|imex:IM-21659-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N|uniprotkb:Q96KQ7(identity)|entrezgene/locuslink:10919(identity)|ddbj/embl/genbank:BC002686(identity) refseq:NP_001124319.1|refseq:NP_004199.1|refseq:NP_665811.1|refseq:NP_001124318.2|rcsb pdb:5FS6|rcsb pdb:5FS7|rcsb pdb:5FS8|rcsb pdb:5FS9|rcsb pdb:5KVH|rcsb pdb:5KVI|ensembl:ENSG00000156709(gene)|ensembl:ENST00000287295(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016651"("oxidoreductase activity, acting on NAD(P)H")|go:"GO:0030182"(neuron differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0071949"(FAD binding)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902510"(regulation of apoptotic DNA fragmentation)|go:"GO:1904045"(cellular response to aldosterone)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR029324|interpro:IPR036188|mint:O95831|rcsb pdb:1M6I|rcsb pdb:4BUR|rcsb pdb:4BV6|rcsb pdb:4FDC|rcsb pdb:4LII|rcsb pdb:5FMH|dip:DIP-32975N|uniprotkb:O95831(identity)|entrezgene/locuslink:9131(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606 rogid:tAY+mPStfDGbCN4OpvHF4ljQ69I9606 intact-crc:DF5A0BA9527327D9|rigid:oWWJg7mMoNQjDoC06tdFKt7VzZY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96KQ7 uniprotkb:P01040 intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957 intact:EBI-724303|ensembl:ENSP00000264474|uniprotkb:Q6IB90 psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym) psi-mi:cyta_human(display_long)|uniprotkb:Cystatin-AS(gene name synonym)|uniprotkb:Stefin-A(gene name synonym)|uniprotkb:CSTA(gene name)|psi-mi:CSTA(display_short)|uniprotkb:STF1(gene name synonym)|uniprotkb:STFA(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832899|imex:IM-21659-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N|uniprotkb:Q96KQ7(identity)|entrezgene/locuslink:10919(identity)|ddbj/embl/genbank:BC002686(identity) refseq:NP_005204.1|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR001713(Proteinase inhibitor I25A, stefin A)|mint:P01040|rcsb pdb:1CYU|rcsb pdb:1CYV|rcsb pdb:1DVC|rcsb pdb:1DVD|rcsb pdb:1GD3|rcsb pdb:1GD4|rcsb pdb:1N9J|rcsb pdb:1NB3|rcsb pdb:1NB5|rcsb pdb:3K9M|rcsb pdb:3KFQ|interpro:IPR018073|rcsb pdb:3KSE|reactome:R-HSA-6809371|ensembl:ENSG00000121552(gene)|ensembl:ENST00000264474(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002020"(protease binding)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0045861"(negative regulation of proteolysis)|uniprotkb:P01040(identity)|entrezgene/locuslink:1475(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606 rogid:SzbpyWUHlOtItIvffzuwhcqFsDI9606 intact-crc:DF5A0BA9527327D9|rigid:oWWJg7mMoNQjDoC06tdFKt7VzZY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96KQ7 uniprotkb:P49720 intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957 intact:EBI-603340|uniprotkb:P31147|uniprotkb:Q0P6J7|uniprotkb:Q96E27|ensembl:ENSP00000483688|ensembl:ENSP00000483956 psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym) psi-mi:psb3_human(display_long)|uniprotkb:PSMB3(gene name)|psi-mi:PSMB3(display_short)|uniprotkb:Proteasome theta chain(gene name synonym)|uniprotkb:Proteasome chain 13(gene name synonym)|uniprotkb:Proteasome component C10-II(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832899|imex:IM-21659-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N|uniprotkb:Q96KQ7(identity)|entrezgene/locuslink:10919(identity)|ddbj/embl/genbank:BC002686(identity) refseq:NP_002786.2|dip:DIP-33846N|ensembl:ENSG00000275903(gene)|ensembl:ENSG00000277791(gene)|ensembl:ENST00000619426(transcript)|ensembl:ENST00000619951(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR033811|mint:P49720|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|uniprotkb:P49720(identity)|entrezgene/locuslink:5691(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606 rogid:H4UDdXV1BaXHp6mEPafNy+Iv8389606 intact-crc:DF5A0BA9527327D9|rigid:oWWJg7mMoNQjDoC06tdFKt7VzZY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96KQ7 uniprotkb:P12273 intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957 intact:EBI-1049746|uniprotkb:A0A963|uniprotkb:A0A9C3|uniprotkb:A0A9F3|uniprotkb:A4D2I1|ensembl:ENSP00000291009 psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym) psi-mi:pip_human(display_long)|uniprotkb:Prolactin-induced protein(gene name synonym)|uniprotkb:Secretory actin-binding protein(gene name synonym)|uniprotkb:Gross cystic disease fluid protein 15(gene name synonym)|uniprotkb:gp17(gene name synonym)|uniprotkb:PIP(gene name)|psi-mi:PIP(display_short)|uniprotkb:GCDFP15(gene name synonym)|uniprotkb:GPIP4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832899|imex:IM-21659-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N|uniprotkb:Q96KQ7(identity)|entrezgene/locuslink:10919(identity)|ddbj/embl/genbank:BC002686(identity) refseq:NP_002643.1|ensembl:ENSG00000159763(gene)|ensembl:ENST00000291009(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0003779"(actin binding)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0006508"(proteolysis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019864"(IgG binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|interpro:IPR007990(Seminal vesicle autoantigen)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|mint:P12273|rcsb pdb:3ES6|reactome:R-HSA-5223345|go:"GO:0001580"(detection of chemical stimulus involved in sensory perception of bitter taste)|uniprotkb:P12273(identity)|entrezgene/locuslink:5304(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606 rogid:/OC16zeRzFp520uPPLHh+WekPPc9606 intact-crc:DF5A0BA9527327D9|rigid:oWWJg7mMoNQjDoC06tdFKt7VzZY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96KQ7 uniprotkb:O00487 intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957 intact:EBI-722193|uniprotkb:O00176|uniprotkb:B3KNW2|ensembl:ENSP00000386541 psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym) psi-mi:psde_human(display_long)|uniprotkb:26S proteasome regulatory subunit RPN11(gene name synonym)|uniprotkb:26S proteasome-associated PAD1 homolog 1(gene name synonym)|uniprotkb:PSMD14(gene name)|psi-mi:PSMD14(display_short)|uniprotkb:POH1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832899|imex:IM-21659-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N|uniprotkb:Q96KQ7(identity)|entrezgene/locuslink:10919(identity)|ddbj/embl/genbank:BC002686(identity) refseq:NP_005796.1|ensembl:ENSG00000115233(gene)|ensembl:ENST00000409682(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070628"(proteasome binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR035299|interpro:IPR037518|mint:O00487|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|uniprotkb:O00487(identity)|entrezgene/locuslink:10213(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606 rogid:pSM+755ZbQisR5S0ZivcYBu9Bc49606 intact-crc:DF5A0BA9527327D9|rigid:oWWJg7mMoNQjDoC06tdFKt7VzZY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92800 uniprotkb:P53004 intact:EBI-8830732|uniprotkb:B4E3R7|uniprotkb:O43287|uniprotkb:A6NCH6|uniprotkb:Q14459|uniprotkb:Q53XP3|uniprotkb:B4DSS2|uniprotkb:B4DIJ1|uniprotkb:B4DIZ7|ensembl:ENSP00000404658|ensembl:ENSP00000466924 intact:EBI-7410441|intact:MINT-1212210|uniprotkb:Q96QL4|uniprotkb:A8K747|uniprotkb:Q9BRW8|uniprotkb:Q86UX0|uniprotkb:O95019|ensembl:ENSP00000265523|ensembl:ENSP00000385757 psi-mi:ezh1_human(display_long)|uniprotkb:ENX-2(gene name synonym)|uniprotkb:Enhancer of zeste homolog 1(gene name synonym)|uniprotkb:KIAA0388(gene name synonym)|uniprotkb:EZH1(gene name)|psi-mi:EZH1(display_short) psi-mi:biea_human(display_long)|uniprotkb:BLVRA(gene name)|psi-mi:BLVRA(display_short)|uniprotkb:BLVR(gene name synonym)|uniprotkb:BVR(gene name synonym)|uniprotkb:Biliverdin-IX alpha-reductase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832980|imex:IM-21659-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308008.1|refseq:NP_001308010.1|refseq:NP_001308011.1|refseq:NP_001982.2|dip:DIP-58580N|ensembl:ENSG00000108799(gene)|ensembl:ENST00000428826(transcript)|ensembl:ENST00000592743(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0021766"(hippocampus development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0031507"(heterochromatin assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR021654|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR032926|interpro:IPR041343|interpro:IPR041355|interpro:IPR044438|mint:Q92800|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|uniprotkb:Q92800(identity)|ddbj/embl/genbank:BC015882(identity)|entrezgene/locuslink:2145(identity) refseq:XP_011513776.1|refseq:NP_001240752.1|refseq:NP_000703.2|refseq:XP_016868009.1|ensembl:ENSG00000106605(gene)|ensembl:ENST00000265523(transcript)|ensembl:ENST00000402924(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0004074"("biliverdin reductase (NAD(P)+) activity")|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042167"(heme catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106276"(biliberdin reductase NAD+ activity)|go:"GO:0106277"("biliverdin reductase (NADP+) activity")|interpro:IPR000683(Oxidoreductase, N-terminal)|interpro:IPR015249(Biliverdin reductase, catalytic)|interpro:IPR017094(Biliverdin reductase A)|interpro:IPR036291|rcsb pdb:2H63|reactome:R-HSA-189483|reactome:R-HSA-9707564|dip:DIP-42180N|uniprotkb:P53004(identity)|entrezgene/locuslink:644(identity) psi-mi:"MI:0469"(intact) - comment:mint|function:Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qp3eqBCgiaoA6VSSyqpW1d9YKN49606 rogid:gcpdPe6YxaYS3dRJ3JRAeEpJbtk9606 intact-crc:B9B6CDFC912F22C2|rigid:sIycgc7AqGlSMVHANHK/1j1uCvg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92800 uniprotkb:Q6ZN18 intact:EBI-8830732|uniprotkb:B4E3R7|uniprotkb:O43287|uniprotkb:A6NCH6|uniprotkb:Q14459|uniprotkb:Q53XP3|uniprotkb:B4DSS2|uniprotkb:B4DIJ1|uniprotkb:B4DIZ7|ensembl:ENSP00000404658|ensembl:ENSP00000466924 intact:EBI-743256|ensembl:ENSP00000381840|uniprotkb:Q59FS5|uniprotkb:Q6ZN62|uniprotkb:Q96BG3 psi-mi:ezh1_human(display_long)|uniprotkb:ENX-2(gene name synonym)|uniprotkb:Enhancer of zeste homolog 1(gene name synonym)|uniprotkb:KIAA0388(gene name synonym)|uniprotkb:EZH1(gene name)|psi-mi:EZH1(display_short) psi-mi:aebp2_human(display_long)|uniprotkb:Adipocyte enhancer-binding protein 2(gene name synonym)|uniprotkb:AEBP2(gene name)|psi-mi:AEBP2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832980|imex:IM-21659-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308008.1|refseq:NP_001308010.1|refseq:NP_001308011.1|refseq:NP_001982.2|dip:DIP-58580N|ensembl:ENSG00000108799(gene)|ensembl:ENST00000428826(transcript)|ensembl:ENST00000592743(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0021766"(hippocampus development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0031507"(heterochromatin assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR021654|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR032926|interpro:IPR041343|interpro:IPR041355|interpro:IPR044438|mint:Q92800|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|uniprotkb:Q92800(identity)|ddbj/embl/genbank:BC015882(identity)|entrezgene/locuslink:2145(identity) ensembl:ENSG00000139154(gene)|interpro:IPR036236|ensembl:ENST00000398864(transcript)|go:"GO:0000785"(chromatin)|mint:Q6ZN18|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001107648.1|refseq:NP_694939.2|rcsb pdb:5WAI|rcsb pdb:5Y0U|rcsb pdb:5Y1U|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|reactome:R-HSA-3214841|refseq:NP_001253972.1|dip:DIP-58581N|uniprotkb:Q6ZN18(identity)|entrezgene/locuslink:121536(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qp3eqBCgiaoA6VSSyqpW1d9YKN49606 rogid:mOY+NOTaqJlXjW8v6D3YPnfnfBU9606 intact-crc:B9B6CDFC912F22C2|rigid:sIycgc7AqGlSMVHANHK/1j1uCvg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92800 uniprotkb:Q09028 intact:EBI-8830732|uniprotkb:B4E3R7|uniprotkb:O43287|uniprotkb:A6NCH6|uniprotkb:Q14459|uniprotkb:Q53XP3|uniprotkb:B4DSS2|uniprotkb:B4DIJ1|uniprotkb:B4DIZ7|ensembl:ENSP00000404658|ensembl:ENSP00000466924 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 psi-mi:ezh1_human(display_long)|uniprotkb:ENX-2(gene name synonym)|uniprotkb:Enhancer of zeste homolog 1(gene name synonym)|uniprotkb:KIAA0388(gene name synonym)|uniprotkb:EZH1(gene name)|psi-mi:EZH1(display_short) psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832980|imex:IM-21659-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308008.1|refseq:NP_001308010.1|refseq:NP_001308011.1|refseq:NP_001982.2|dip:DIP-58580N|ensembl:ENSG00000108799(gene)|ensembl:ENST00000428826(transcript)|ensembl:ENST00000592743(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0021766"(hippocampus development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0031507"(heterochromatin assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR021654|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR032926|interpro:IPR041343|interpro:IPR041355|interpro:IPR044438|mint:Q92800|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|uniprotkb:Q92800(identity)|ddbj/embl/genbank:BC015882(identity)|entrezgene/locuslink:2145(identity) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|entrezgene/locuslink:5928(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qp3eqBCgiaoA6VSSyqpW1d9YKN49606 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 intact-crc:B9B6CDFC912F22C2|rigid:sIycgc7AqGlSMVHANHK/1j1uCvg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92800 uniprotkb:Q9Y483 intact:EBI-8830732|uniprotkb:B4E3R7|uniprotkb:O43287|uniprotkb:A6NCH6|uniprotkb:Q14459|uniprotkb:Q53XP3|uniprotkb:B4DSS2|uniprotkb:B4DIJ1|uniprotkb:B4DIZ7|ensembl:ENSP00000404658|ensembl:ENSP00000466924 intact:EBI-725816|uniprotkb:A6NGQ9|uniprotkb:Q9UES9|uniprotkb:Q9UP40|uniprotkb:A8K2Q3|uniprotkb:B1AKT5|intact:EBI-11028207|uniprotkb:Q96G26|uniprotkb:B1AKT6|ensembl:ENSP00000359321 psi-mi:ezh1_human(display_long)|uniprotkb:ENX-2(gene name synonym)|uniprotkb:Enhancer of zeste homolog 1(gene name synonym)|uniprotkb:KIAA0388(gene name synonym)|uniprotkb:EZH1(gene name)|psi-mi:EZH1(display_short) psi-mi:mtf2_human(display_long)|uniprotkb:PCL2(gene name synonym)|uniprotkb:Metal-response element DNA-binding protein M96(gene name synonym)|uniprotkb:Metal regulatory transcription factor 2(gene name synonym)|uniprotkb:Polycomb-like protein 2(gene name synonym)|uniprotkb:MTF2(gene name)|psi-mi:MTF2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832980|imex:IM-21659-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308008.1|refseq:NP_001308010.1|refseq:NP_001308011.1|refseq:NP_001982.2|dip:DIP-58580N|ensembl:ENSG00000108799(gene)|ensembl:ENST00000428826(transcript)|ensembl:ENST00000592743(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0021766"(hippocampus development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0031507"(heterochromatin assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR021654|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR032926|interpro:IPR041343|interpro:IPR041355|interpro:IPR044438|mint:Q92800|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|uniprotkb:Q92800(identity)|ddbj/embl/genbank:BC015882(identity)|entrezgene/locuslink:2145(identity) refseq:NP_001157863.1|refseq:NP_001157865.1|refseq:NP_031384.1|refseq:XP_011539318.1|refseq:XP_016856165.1|ensembl:ENSG00000143033(gene)|ensembl:ENST00000370298(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042015|mint:Q9Y483|rcsb pdb:5XFR|reactome:R-HSA-212300|interpro:IPR042014|refseq:NP_001157864.1|uniprotkb:Q9Y483(identity)|entrezgene/locuslink:22823(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qp3eqBCgiaoA6VSSyqpW1d9YKN49606 rogid:Im8E6U/OPb8AEir43AUUDlU6F2o9606 intact-crc:B9B6CDFC912F22C2|rigid:sIycgc7AqGlSMVHANHK/1j1uCvg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92800 uniprotkb:Q92833 intact:EBI-8830732|uniprotkb:B4E3R7|uniprotkb:O43287|uniprotkb:A6NCH6|uniprotkb:Q14459|uniprotkb:Q53XP3|uniprotkb:B4DSS2|uniprotkb:B4DIJ1|uniprotkb:B4DIZ7|ensembl:ENSP00000404658|ensembl:ENSP00000466924 intact:EBI-1222720|uniprotkb:Q5U5L5|uniprotkb:A8K9Z6|uniprotkb:B7Z5S5|uniprotkb:Q86X63|uniprotkb:B7Z8L0|ensembl:ENSP00000341280 psi-mi:ezh1_human(display_long)|uniprotkb:ENX-2(gene name synonym)|uniprotkb:Enhancer of zeste homolog 1(gene name synonym)|uniprotkb:KIAA0388(gene name synonym)|uniprotkb:EZH1(gene name)|psi-mi:EZH1(display_short) psi-mi:jard2_human(display_long)|uniprotkb:JARID2(gene name)|psi-mi:JARID2(display_short)|uniprotkb:JMJ(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832980|imex:IM-21659-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308008.1|refseq:NP_001308010.1|refseq:NP_001308011.1|refseq:NP_001982.2|dip:DIP-58580N|ensembl:ENSG00000108799(gene)|ensembl:ENST00000428826(transcript)|ensembl:ENST00000592743(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0021766"(hippocampus development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0031507"(heterochromatin assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR021654|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR032926|interpro:IPR041343|interpro:IPR041355|interpro:IPR044438|mint:Q92800|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|uniprotkb:Q92800(identity)|ddbj/embl/genbank:BC015882(identity)|entrezgene/locuslink:2145(identity) refseq:NP_004964.2|refseq:NP_001253969.1|refseq:XP_005249146.1|refseq:XP_016866323.1|refseq:XP_016866324.1|dip:DIP-45494N|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR036431|mint:Q92833|rcsb pdb:5HYN|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000008083(gene)|ensembl:ENST00000341776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007417"(central nervous system development)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0034721"(histone H3-K4 demethylation, trimethyl-H3-K4-specific)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|uniprotkb:Q92833(identity)|entrezgene/locuslink:3720(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qp3eqBCgiaoA6VSSyqpW1d9YKN49606 rogid:G/oMY7WdV7UyQwfT4MOZyET2fS89606 intact-crc:B9B6CDFC912F22C2|rigid:sIycgc7AqGlSMVHANHK/1j1uCvg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92800 uniprotkb:Q1XH10 intact:EBI-8830732|uniprotkb:B4E3R7|uniprotkb:O43287|uniprotkb:A6NCH6|uniprotkb:Q14459|uniprotkb:Q53XP3|uniprotkb:B4DSS2|uniprotkb:B4DIJ1|uniprotkb:B4DIZ7|ensembl:ENSP00000404658|ensembl:ENSP00000466924 intact:EBI-8832973|uniprotkb:Q6ZMX4|uniprotkb:Q8N3C3|uniprotkb:B1ANA5|uniprotkb:E9PAX1|uniprotkb:F5H7M0|ensembl:ENSP00000410041 psi-mi:ezh1_human(display_long)|uniprotkb:ENX-2(gene name synonym)|uniprotkb:Enhancer of zeste homolog 1(gene name synonym)|uniprotkb:KIAA0388(gene name synonym)|uniprotkb:EZH1(gene name)|psi-mi:EZH1(display_short) psi-mi:skda1_human(display_long)|uniprotkb:C10orf140(gene name synonym)|uniprotkb:DLN1(gene name synonym)|uniprotkb:Protein DLN-1(gene name synonym)|uniprotkb:SKIDA1(gene name)|psi-mi:SKIDA1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832980|imex:IM-21659-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308008.1|refseq:NP_001308010.1|refseq:NP_001308011.1|refseq:NP_001982.2|dip:DIP-58580N|ensembl:ENSG00000108799(gene)|ensembl:ENST00000428826(transcript)|ensembl:ENST00000592743(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0021766"(hippocampus development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0031507"(heterochromatin assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR021654|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR032926|interpro:IPR041343|interpro:IPR041355|interpro:IPR044438|mint:Q92800|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|uniprotkb:Q92800(identity)|ddbj/embl/genbank:BC015882(identity)|entrezgene/locuslink:2145(identity) refseq:XP_011517782.1|refseq:XP_016871714.1|refseq:XP_016871715.1|refseq:NP_997254.3|refseq:XP_005252507.1|ensembl:ENSG00000180592(gene)|ensembl:ENST00000449193(transcript)|interpro:IPR003380(Transforming protein Ski)|interpro:IPR009061(Putative DNA binding)|interpro:IPR027971|interpro:IPR037000|uniprotkb:Q1XH10(identity)|entrezgene/locuslink:387640(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qp3eqBCgiaoA6VSSyqpW1d9YKN49606 rogid:rM6nHmdZz8+n4wjkl/DUhrUeYXE9606 intact-crc:B9B6CDFC912F22C2|rigid:sIycgc7AqGlSMVHANHK/1j1uCvg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92800 uniprotkb:A6NHQ4 intact:EBI-8830732|uniprotkb:B4E3R7|uniprotkb:O43287|uniprotkb:A6NCH6|uniprotkb:Q14459|uniprotkb:Q53XP3|uniprotkb:B4DSS2|uniprotkb:B4DIJ1|uniprotkb:B4DIZ7|ensembl:ENSP00000404658|ensembl:ENSP00000466924 intact:EBI-8831125|ensembl:ENSP00000483859|ensembl:ENSP00000484710 psi-mi:ezh1_human(display_long)|uniprotkb:ENX-2(gene name synonym)|uniprotkb:Enhancer of zeste homolog 1(gene name synonym)|uniprotkb:KIAA0388(gene name synonym)|uniprotkb:EZH1(gene name)|psi-mi:EZH1(display_short) psi-mi:epop_human(display_long)|uniprotkb:EPOP(gene name)|psi-mi:EPOP(display_short)|uniprotkb:C17orf96(gene name synonym)|uniprotkb:PRR28(gene name synonym)|uniprotkb:Proline-rich protein 28(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832980|imex:IM-21659-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308008.1|refseq:NP_001308010.1|refseq:NP_001308011.1|refseq:NP_001982.2|dip:DIP-58580N|ensembl:ENSG00000108799(gene)|ensembl:ENST00000428826(transcript)|ensembl:ENST00000592743(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0021766"(hippocampus development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0031507"(heterochromatin assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR021654|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR032926|interpro:IPR041343|interpro:IPR041355|interpro:IPR044438|mint:Q92800|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|uniprotkb:Q92800(identity)|ddbj/embl/genbank:BC015882(identity)|entrezgene/locuslink:2145(identity) refseq:NP_001124149.1|ensembl:ENSG00000273604(gene)|ensembl:ENST00000613024(transcript)|ensembl:ENST00000621654(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005694"(chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0070449"(elongin complex)|interpro:IPR027971|mint:A6NHQ4|ensembl:ENSG00000277303(gene)|uniprotkb:A6NHQ4(identity)|entrezgene/locuslink:100170841(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qp3eqBCgiaoA6VSSyqpW1d9YKN49606 rogid:xxrapCjRxgY22pLac2F4zSS2bvk9606 intact-crc:B9B6CDFC912F22C2|rigid:sIycgc7AqGlSMVHANHK/1j1uCvg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92800 uniprotkb:Q16576 intact:EBI-8830732|uniprotkb:B4E3R7|uniprotkb:O43287|uniprotkb:A6NCH6|uniprotkb:Q14459|uniprotkb:Q53XP3|uniprotkb:B4DSS2|uniprotkb:B4DIJ1|uniprotkb:B4DIZ7|ensembl:ENSP00000404658|ensembl:ENSP00000466924 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 psi-mi:ezh1_human(display_long)|uniprotkb:ENX-2(gene name synonym)|uniprotkb:Enhancer of zeste homolog 1(gene name synonym)|uniprotkb:KIAA0388(gene name synonym)|uniprotkb:EZH1(gene name)|psi-mi:EZH1(display_short) psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832980|imex:IM-21659-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308008.1|refseq:NP_001308010.1|refseq:NP_001308011.1|refseq:NP_001982.2|dip:DIP-58580N|ensembl:ENSG00000108799(gene)|ensembl:ENST00000428826(transcript)|ensembl:ENST00000592743(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0021766"(hippocampus development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0031507"(heterochromatin assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR021654|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR032926|interpro:IPR041343|interpro:IPR041355|interpro:IPR044438|mint:Q92800|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|uniprotkb:Q92800(identity)|ddbj/embl/genbank:BC015882(identity)|entrezgene/locuslink:2145(identity) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|entrezgene/locuslink:5931(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qp3eqBCgiaoA6VSSyqpW1d9YKN49606 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 intact-crc:B9B6CDFC912F22C2|rigid:sIycgc7AqGlSMVHANHK/1j1uCvg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92800 uniprotkb:O43189 intact:EBI-8830732|uniprotkb:B4E3R7|uniprotkb:O43287|uniprotkb:A6NCH6|uniprotkb:Q14459|uniprotkb:Q53XP3|uniprotkb:B4DSS2|uniprotkb:B4DIJ1|uniprotkb:B4DIZ7|ensembl:ENSP00000404658|ensembl:ENSP00000466924 intact:EBI-530034|uniprotkb:B1AZX2|uniprotkb:B1AZX3|uniprotkb:O60929|uniprotkb:Q96KM7|uniprotkb:Q5SU07|uniprotkb:Q5SU08|ensembl:ENSP00000363640|ensembl:ENSP00000391901|ensembl:ENSP00000407295 psi-mi:ezh1_human(display_long)|uniprotkb:ENX-2(gene name synonym)|uniprotkb:Enhancer of zeste homolog 1(gene name synonym)|uniprotkb:KIAA0388(gene name synonym)|uniprotkb:EZH1(gene name)|psi-mi:EZH1(display_short) psi-mi:phf1_human(display_long)|uniprotkb:PCL1(gene name synonym)|uniprotkb:Polycomb-like protein 1(gene name synonym)|uniprotkb:PHF1(gene name)|psi-mi:PHF1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832980|imex:IM-21659-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308008.1|refseq:NP_001308010.1|refseq:NP_001308011.1|refseq:NP_001982.2|dip:DIP-58580N|ensembl:ENSG00000108799(gene)|ensembl:ENST00000428826(transcript)|ensembl:ENST00000592743(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0021766"(hippocampus development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0031507"(heterochromatin assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR021654|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR032926|interpro:IPR041343|interpro:IPR041355|interpro:IPR044438|mint:Q92800|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|uniprotkb:Q92800(identity)|ddbj/embl/genbank:BC015882(identity)|entrezgene/locuslink:2145(identity) refseq:XP_011512964.1|refseq:NP_002627.1|refseq:NP_077084.1|ensembl:ENSG00000112511(gene)|ensembl:ENSG00000225553(gene)|ensembl:ENST00000374516(transcript)|ensembl:ENST00000427869(transcript)|ensembl:ENST00000454914(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR031202|interpro:IPR040477|mint:O43189|rcsb pdb:2E5P|rcsb pdb:2M0O|rcsb pdb:4HCZ|rcsb pdb:5XFN|rcsb pdb:5XFO|rcsb pdb:5XFP|rcsb pdb:6WAT|rcsb pdb:6WAV|reactome:R-HSA-212300|dip:DIP-34001N|uniprotkb:O43189(identity)|entrezgene/locuslink:5252(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qp3eqBCgiaoA6VSSyqpW1d9YKN49606 rogid:8n8g2LqzuOQb8cFC7tE1j/xBvkI9606 intact-crc:B9B6CDFC912F22C2|rigid:sIycgc7AqGlSMVHANHK/1j1uCvg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92800 uniprotkb:O75530 intact:EBI-8830732|uniprotkb:B4E3R7|uniprotkb:O43287|uniprotkb:A6NCH6|uniprotkb:Q14459|uniprotkb:Q53XP3|uniprotkb:B4DSS2|uniprotkb:B4DIJ1|uniprotkb:B4DIZ7|ensembl:ENSP00000404658|ensembl:ENSP00000466924 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 psi-mi:ezh1_human(display_long)|uniprotkb:ENX-2(gene name synonym)|uniprotkb:Enhancer of zeste homolog 1(gene name synonym)|uniprotkb:KIAA0388(gene name synonym)|uniprotkb:EZH1(gene name)|psi-mi:EZH1(display_short) psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832980|imex:IM-21659-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308008.1|refseq:NP_001308010.1|refseq:NP_001308011.1|refseq:NP_001982.2|dip:DIP-58580N|ensembl:ENSG00000108799(gene)|ensembl:ENST00000428826(transcript)|ensembl:ENST00000592743(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0021766"(hippocampus development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0031507"(heterochromatin assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR021654|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR032926|interpro:IPR041343|interpro:IPR041355|interpro:IPR044438|mint:Q92800|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|uniprotkb:Q92800(identity)|ddbj/embl/genbank:BC015882(identity)|entrezgene/locuslink:2145(identity) refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:O75530(identity)|entrezgene/locuslink:8726(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qp3eqBCgiaoA6VSSyqpW1d9YKN49606 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 intact-crc:B9B6CDFC912F22C2|rigid:sIycgc7AqGlSMVHANHK/1j1uCvg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92800 uniprotkb:Q15022 intact:EBI-8830732|uniprotkb:B4E3R7|uniprotkb:O43287|uniprotkb:A6NCH6|uniprotkb:Q14459|uniprotkb:Q53XP3|uniprotkb:B4DSS2|uniprotkb:B4DIJ1|uniprotkb:B4DIZ7|ensembl:ENSP00000404658|ensembl:ENSP00000466924 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 psi-mi:ezh1_human(display_long)|uniprotkb:ENX-2(gene name synonym)|uniprotkb:Enhancer of zeste homolog 1(gene name synonym)|uniprotkb:KIAA0388(gene name synonym)|uniprotkb:EZH1(gene name)|psi-mi:EZH1(display_short) psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832980|imex:IM-21659-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308008.1|refseq:NP_001308010.1|refseq:NP_001308011.1|refseq:NP_001982.2|dip:DIP-58580N|ensembl:ENSG00000108799(gene)|ensembl:ENST00000428826(transcript)|ensembl:ENST00000592743(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0021766"(hippocampus development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0031507"(heterochromatin assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR021654|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR032926|interpro:IPR041343|interpro:IPR041355|interpro:IPR044438|mint:Q92800|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|uniprotkb:Q92800(identity)|ddbj/embl/genbank:BC015882(identity)|entrezgene/locuslink:2145(identity) dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:Q15022(identity)|entrezgene/locuslink:23512(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qp3eqBCgiaoA6VSSyqpW1d9YKN49606 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 intact-crc:B9B6CDFC912F22C2|rigid:sIycgc7AqGlSMVHANHK/1j1uCvg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92800 uniprotkb:Q96JN0 intact:EBI-8830732|uniprotkb:B4E3R7|uniprotkb:O43287|uniprotkb:A6NCH6|uniprotkb:Q14459|uniprotkb:Q53XP3|uniprotkb:B4DSS2|uniprotkb:B4DIJ1|uniprotkb:B4DIZ7|ensembl:ENSP00000404658|ensembl:ENSP00000466924 intact:EBI-746045|uniprotkb:Q9H945|uniprotkb:Q9Y457|ensembl:ENSP00000348298|ensembl:ENSP00000360138|ensembl:ENSP00000360144|ensembl:ENSP00000501560|ensembl:ENSP00000501639|ensembl:ENSP00000502633|intact:EBI-8833163|uniprotkb:D3DR47|uniprotkb:Q5VW16|uniprotkb:Q7Z723|uniprotkb:Q86T32|uniprotkb:Q86T33|uniprotkb:Q8N3L6|uniprotkb:Q8N655 psi-mi:ezh1_human(display_long)|uniprotkb:ENX-2(gene name synonym)|uniprotkb:Enhancer of zeste homolog 1(gene name synonym)|uniprotkb:KIAA0388(gene name synonym)|uniprotkb:EZH1(gene name)|psi-mi:EZH1(display_short) psi-mi:lcor_human(display_long)|uniprotkb:LCOR(gene name)|psi-mi:LCOR(display_short)|uniprotkb:C10orf12(gene name synonym)|uniprotkb:KIAA1795(gene name synonym)|uniprotkb:MLR2(gene name synonym)|uniprotkb:Mblk1-related protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832980|imex:IM-21659-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308008.1|refseq:NP_001308010.1|refseq:NP_001308011.1|refseq:NP_001982.2|dip:DIP-58580N|ensembl:ENSG00000108799(gene)|ensembl:ENST00000428826(transcript)|ensembl:ENST00000592743(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0021766"(hippocampus development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0031507"(heterochromatin assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR021654|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR032926|interpro:IPR041343|interpro:IPR041355|interpro:IPR044438|mint:Q92800|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|uniprotkb:Q92800(identity)|ddbj/embl/genbank:BC015882(identity)|entrezgene/locuslink:2145(identity) ensembl:ENSG00000196233(gene)|ensembl:ENST00000356016(transcript)|ensembl:ENST00000371097(transcript)|ensembl:ENST00000371103(transcript)|ensembl:ENST00000675471(transcript)|ensembl:ENST00000675537(transcript)|ensembl:ENST00000675971(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|mint:Q96JN0|rcsb pdb:2COB|refseq:NP_001164236.1|refseq:NP_001164237.1|refseq:NP_115816.2|refseq:XP_016872275.1|refseq:XP_016872276.1|refseq:XP_016872277.1|refseq:NP_001333445.1|uniprotkb:Q8N655(identity)|entrezgene/locuslink:26148(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qp3eqBCgiaoA6VSSyqpW1d9YKN49606 rogid:cOnk6EDDff86yaG1uG+dxEQ1Z689606 intact-crc:B9B6CDFC912F22C2|rigid:sIycgc7AqGlSMVHANHK/1j1uCvg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92800 uniprotkb:Q5T6S3 intact:EBI-8830732|uniprotkb:B4E3R7|uniprotkb:O43287|uniprotkb:A6NCH6|uniprotkb:Q14459|uniprotkb:Q53XP3|uniprotkb:B4DSS2|uniprotkb:B4DIJ1|uniprotkb:B4DIZ7|ensembl:ENSP00000404658|ensembl:ENSP00000466924 intact:EBI-2339674|uniprotkb:Q6N038|uniprotkb:Q32NF2|uniprotkb:Q8TBL6|uniprotkb:Q5T6S4|uniprotkb:Q9UFS9|ensembl:ENSP00000363003 psi-mi:ezh1_human(display_long)|uniprotkb:ENX-2(gene name synonym)|uniprotkb:Enhancer of zeste homolog 1(gene name synonym)|uniprotkb:KIAA0388(gene name synonym)|uniprotkb:EZH1(gene name)|psi-mi:EZH1(display_short) psi-mi:phf19_human(display_long)|uniprotkb:PHF19(gene name)|psi-mi:PHF19(display_short)|uniprotkb:PCL3(gene name synonym)|uniprotkb:Polycomb-like protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8832980|imex:IM-21659-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308008.1|refseq:NP_001308010.1|refseq:NP_001308011.1|refseq:NP_001982.2|dip:DIP-58580N|ensembl:ENSG00000108799(gene)|ensembl:ENST00000428826(transcript)|ensembl:ENST00000592743(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0021766"(hippocampus development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0031507"(heterochromatin assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR021654|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR032926|interpro:IPR041343|interpro:IPR041355|interpro:IPR044438|mint:Q92800|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|uniprotkb:Q92800(identity)|ddbj/embl/genbank:BC015882(identity)|entrezgene/locuslink:2145(identity) refseq:XP_011516811.1|refseq:NP_001009936.1|refseq:NP_056466.1|refseq:NP_001273769.1|refseq:NP_001273772.1|refseq:XP_005251963.1|refseq:XP_016870101.1|ensembl:ENSG00000119403(gene)|ensembl:ENST00000373896(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042017|mint:Q5T6S3|rcsb pdb:2E5Q|rcsb pdb:4BD3|rcsb pdb:6NQ3|rcsb pdb:6WAU|reactome:R-HSA-212300|uniprotkb:Q5T6S3(identity)|entrezgene/locuslink:26147(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qp3eqBCgiaoA6VSSyqpW1d9YKN49606 rogid:K4sKpUT1htSiigJaEoGyDjvkWqc9606 intact-crc:B9B6CDFC912F22C2|rigid:sIycgc7AqGlSMVHANHK/1j1uCvg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15910 uniprotkb:P84243 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 intact:EBI-120658|uniprotkb:P06351|uniprotkb:P33155|uniprotkb:Q5VV55|uniprotkb:Q5VV56|uniprotkb:Q66I33|uniprotkb:Q9V3W4|ensembl:ENSP00000254810|ensembl:ENSP00000355778|ensembl:ENSP00000355780|ensembl:ENSP00000355781|ensembl:ENSP00000465813|ensembl:ENSP00000466020|ensembl:ENSP00000468714|ensembl:ENSP00000499275|ensembl:ENSP00000499385|ensembl:ENSP00000499800 psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:h33_human(display_long)|uniprotkb:H3-3A(gene name)|psi-mi:H3-3A(display_short)|uniprotkb:H3-3B(gene name)|psi-mi:H3-3B(display_short)|uniprotkb:H3.3A(gene name synonym)|uniprotkb:H3.3B(gene name synonym)|uniprotkb:H3F3(gene name synonym)|uniprotkb:H3F3A(gene name synonym)|uniprotkb:H3F3B(gene name synonym)|uniprotkb:PP781(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833042|imex:IM-21659-24 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N|uniprotkb:Q15910(identity)|entrezgene/locuslink:2146(identity)|ddbj/embl/genbank:BC010858(identity) refseq:NP_002098.1|refseq:NP_005315.1|rcsb pdb:4H9N|rcsb pdb:3QL9|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:3QLA|rcsb pdb:3QLC|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4L58|rcsb pdb:4N4I|rcsb pdb:3WTP|rcsb pdb:4O62|rcsb pdb:4QQ4|rcsb pdb:4TMP|rcsb pdb:4GNE|rcsb pdb:4GNF|rcsb pdb:4U7T|rcsb pdb:4GNG|rcsb pdb:4W5A|rcsb pdb:4GU0|rcsb pdb:4GUR|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:4GUS|rcsb pdb:4GY5|rcsb pdb:5DWQ|rcsb pdb:5DX0|rcsb pdb:5JA4|rcsb pdb:5JJY|ensembl:ENSG00000132475(gene)|ensembl:ENSG00000163041(gene)|rcsb pdb:5JLB|rcsb pdb:5KDM|rcsb pdb:5X7X|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6HGT|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6J9J|rcsb pdb:6PZV|rcsb pdb:6QXZ|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6U04|rcsb pdb:7A08|reactome:R-HSA-427413|rcsb pdb:7CIZ|reactome:R-HSA-5250924|reactome:R-HSA-5334118|rcsb pdb:7CJ0|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-983231|rcsb pdb:7CWH|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-427359|reactome:R-HSA-427389|ensembl:ENST00000254810(transcript)|ensembl:ENST00000366813(transcript)|ensembl:ENST00000366815(transcript)|ensembl:ENST00000366816(transcript)|ensembl:ENST00000586607(transcript)|ensembl:ENST00000587560(transcript)|ensembl:ENST00000589599(transcript)|ensembl:ENST00000655399(transcript)|ensembl:ENST00000661429(transcript)|ensembl:ENST00000666609(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P84243|rcsb pdb:2L43|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3AV2|rcsb pdb:3JVK|rcsb pdb:3MUK|rcsb pdb:3MUL|dip:DIP-40046N|uniprotkb:P84243(identity)|entrezgene/locuslink:3021(identity)|entrezgene/locuslink:3020(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 rogid:cRqA5/IBNfIbbxAnbwLqzXip20I9606 intact-crc:99A0984E621AEFA6|rigid:TlyqbJeq5zrIcThDn/ds98akRbQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15910 uniprotkb:Q15022 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833042|imex:IM-21659-24 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N|uniprotkb:Q15910(identity)|entrezgene/locuslink:2146(identity)|ddbj/embl/genbank:BC010858(identity) dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:Q15022(identity)|entrezgene/locuslink:23512(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 intact-crc:99A0984E621AEFA6|rigid:TlyqbJeq5zrIcThDn/ds98akRbQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15910 uniprotkb:Q6ZN18 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 intact:EBI-743256|ensembl:ENSP00000381840|uniprotkb:Q59FS5|uniprotkb:Q6ZN62|uniprotkb:Q96BG3 psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:aebp2_human(display_long)|uniprotkb:Adipocyte enhancer-binding protein 2(gene name synonym)|uniprotkb:AEBP2(gene name)|psi-mi:AEBP2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833042|imex:IM-21659-24 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N|uniprotkb:Q15910(identity)|entrezgene/locuslink:2146(identity)|ddbj/embl/genbank:BC010858(identity) ensembl:ENSG00000139154(gene)|interpro:IPR036236|ensembl:ENST00000398864(transcript)|go:"GO:0000785"(chromatin)|mint:Q6ZN18|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001107648.1|refseq:NP_694939.2|rcsb pdb:5WAI|rcsb pdb:5Y0U|rcsb pdb:5Y1U|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|reactome:R-HSA-3214841|refseq:NP_001253972.1|dip:DIP-58581N|uniprotkb:Q6ZN18(identity)|entrezgene/locuslink:121536(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 rogid:mOY+NOTaqJlXjW8v6D3YPnfnfBU9606 intact-crc:99A0984E621AEFA6|rigid:TlyqbJeq5zrIcThDn/ds98akRbQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15910 uniprotkb:Q5T6S3 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 intact:EBI-2339674|uniprotkb:Q6N038|uniprotkb:Q32NF2|uniprotkb:Q8TBL6|uniprotkb:Q5T6S4|uniprotkb:Q9UFS9|ensembl:ENSP00000363003 psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:phf19_human(display_long)|uniprotkb:PHF19(gene name)|psi-mi:PHF19(display_short)|uniprotkb:PCL3(gene name synonym)|uniprotkb:Polycomb-like protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833042|imex:IM-21659-24 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N|uniprotkb:Q15910(identity)|entrezgene/locuslink:2146(identity)|ddbj/embl/genbank:BC010858(identity) refseq:XP_011516811.1|refseq:NP_001009936.1|refseq:NP_056466.1|refseq:NP_001273769.1|refseq:NP_001273772.1|refseq:XP_005251963.1|refseq:XP_016870101.1|ensembl:ENSG00000119403(gene)|ensembl:ENST00000373896(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042017|mint:Q5T6S3|rcsb pdb:2E5Q|rcsb pdb:4BD3|rcsb pdb:6NQ3|rcsb pdb:6WAU|reactome:R-HSA-212300|uniprotkb:Q5T6S3(identity)|entrezgene/locuslink:26147(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 rogid:K4sKpUT1htSiigJaEoGyDjvkWqc9606 intact-crc:99A0984E621AEFA6|rigid:TlyqbJeq5zrIcThDn/ds98akRbQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15910 uniprotkb:Q92833 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 intact:EBI-1222720|uniprotkb:Q5U5L5|uniprotkb:A8K9Z6|uniprotkb:B7Z5S5|uniprotkb:Q86X63|uniprotkb:B7Z8L0|ensembl:ENSP00000341280 psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:jard2_human(display_long)|uniprotkb:JARID2(gene name)|psi-mi:JARID2(display_short)|uniprotkb:JMJ(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833042|imex:IM-21659-24 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N|uniprotkb:Q15910(identity)|entrezgene/locuslink:2146(identity)|ddbj/embl/genbank:BC010858(identity) refseq:NP_004964.2|refseq:NP_001253969.1|refseq:XP_005249146.1|refseq:XP_016866323.1|refseq:XP_016866324.1|dip:DIP-45494N|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR036431|mint:Q92833|rcsb pdb:5HYN|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000008083(gene)|ensembl:ENST00000341776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007417"(central nervous system development)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0034721"(histone H3-K4 demethylation, trimethyl-H3-K4-specific)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|uniprotkb:Q92833(identity)|entrezgene/locuslink:3720(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 rogid:G/oMY7WdV7UyQwfT4MOZyET2fS89606 intact-crc:99A0984E621AEFA6|rigid:TlyqbJeq5zrIcThDn/ds98akRbQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15910 uniprotkb:Q09028 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833042|imex:IM-21659-24 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N|uniprotkb:Q15910(identity)|entrezgene/locuslink:2146(identity)|ddbj/embl/genbank:BC010858(identity) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|entrezgene/locuslink:5928(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 intact-crc:99A0984E621AEFA6|rigid:TlyqbJeq5zrIcThDn/ds98akRbQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15910 uniprotkb:Q96JN0 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 intact:EBI-746045|uniprotkb:Q9H945|uniprotkb:Q9Y457|ensembl:ENSP00000348298|ensembl:ENSP00000360138|ensembl:ENSP00000360144|ensembl:ENSP00000501560|ensembl:ENSP00000501639|ensembl:ENSP00000502633|intact:EBI-8833163|uniprotkb:D3DR47|uniprotkb:Q5VW16|uniprotkb:Q7Z723|uniprotkb:Q86T32|uniprotkb:Q86T33|uniprotkb:Q8N3L6|uniprotkb:Q8N655 psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:lcor_human(display_long)|uniprotkb:LCOR(gene name)|psi-mi:LCOR(display_short)|uniprotkb:C10orf12(gene name synonym)|uniprotkb:KIAA1795(gene name synonym)|uniprotkb:MLR2(gene name synonym)|uniprotkb:Mblk1-related protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833042|imex:IM-21659-24 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N|uniprotkb:Q15910(identity)|entrezgene/locuslink:2146(identity)|ddbj/embl/genbank:BC010858(identity) ensembl:ENSG00000196233(gene)|ensembl:ENST00000356016(transcript)|ensembl:ENST00000371097(transcript)|ensembl:ENST00000371103(transcript)|ensembl:ENST00000675471(transcript)|ensembl:ENST00000675537(transcript)|ensembl:ENST00000675971(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|mint:Q96JN0|rcsb pdb:2COB|refseq:NP_001164236.1|refseq:NP_001164237.1|refseq:NP_115816.2|refseq:XP_016872275.1|refseq:XP_016872276.1|refseq:XP_016872277.1|refseq:NP_001333445.1|uniprotkb:Q8N655(identity)|entrezgene/locuslink:26148(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 rogid:cOnk6EDDff86yaG1uG+dxEQ1Z689606 intact-crc:99A0984E621AEFA6|rigid:TlyqbJeq5zrIcThDn/ds98akRbQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15910 uniprotkb:A6NHQ4 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 intact:EBI-8831125|ensembl:ENSP00000483859|ensembl:ENSP00000484710 psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:epop_human(display_long)|uniprotkb:EPOP(gene name)|psi-mi:EPOP(display_short)|uniprotkb:C17orf96(gene name synonym)|uniprotkb:PRR28(gene name synonym)|uniprotkb:Proline-rich protein 28(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833042|imex:IM-21659-24 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N|uniprotkb:Q15910(identity)|entrezgene/locuslink:2146(identity)|ddbj/embl/genbank:BC010858(identity) refseq:NP_001124149.1|ensembl:ENSG00000273604(gene)|ensembl:ENST00000613024(transcript)|ensembl:ENST00000621654(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005694"(chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0070449"(elongin complex)|interpro:IPR027971|mint:A6NHQ4|ensembl:ENSG00000277303(gene)|uniprotkb:A6NHQ4(identity)|entrezgene/locuslink:100170841(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 rogid:xxrapCjRxgY22pLac2F4zSS2bvk9606 intact-crc:99A0984E621AEFA6|rigid:TlyqbJeq5zrIcThDn/ds98akRbQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15910 uniprotkb:Q9Y483 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 intact:EBI-725816|uniprotkb:A6NGQ9|uniprotkb:Q9UES9|uniprotkb:Q9UP40|uniprotkb:A8K2Q3|uniprotkb:B1AKT5|intact:EBI-11028207|uniprotkb:Q96G26|uniprotkb:B1AKT6|ensembl:ENSP00000359321 psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:mtf2_human(display_long)|uniprotkb:PCL2(gene name synonym)|uniprotkb:Metal-response element DNA-binding protein M96(gene name synonym)|uniprotkb:Metal regulatory transcription factor 2(gene name synonym)|uniprotkb:Polycomb-like protein 2(gene name synonym)|uniprotkb:MTF2(gene name)|psi-mi:MTF2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833042|imex:IM-21659-24 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N|uniprotkb:Q15910(identity)|entrezgene/locuslink:2146(identity)|ddbj/embl/genbank:BC010858(identity) refseq:NP_001157863.1|refseq:NP_001157865.1|refseq:NP_031384.1|refseq:XP_011539318.1|refseq:XP_016856165.1|ensembl:ENSG00000143033(gene)|ensembl:ENST00000370298(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042015|mint:Q9Y483|rcsb pdb:5XFR|reactome:R-HSA-212300|interpro:IPR042014|refseq:NP_001157864.1|uniprotkb:Q9Y483(identity)|entrezgene/locuslink:22823(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 rogid:Im8E6U/OPb8AEir43AUUDlU6F2o9606 intact-crc:99A0984E621AEFA6|rigid:TlyqbJeq5zrIcThDn/ds98akRbQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15910 uniprotkb:O43189 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 intact:EBI-530034|uniprotkb:B1AZX2|uniprotkb:B1AZX3|uniprotkb:O60929|uniprotkb:Q96KM7|uniprotkb:Q5SU07|uniprotkb:Q5SU08|ensembl:ENSP00000363640|ensembl:ENSP00000391901|ensembl:ENSP00000407295 psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:phf1_human(display_long)|uniprotkb:PCL1(gene name synonym)|uniprotkb:Polycomb-like protein 1(gene name synonym)|uniprotkb:PHF1(gene name)|psi-mi:PHF1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833042|imex:IM-21659-24 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N|uniprotkb:Q15910(identity)|entrezgene/locuslink:2146(identity)|ddbj/embl/genbank:BC010858(identity) refseq:XP_011512964.1|refseq:NP_002627.1|refseq:NP_077084.1|ensembl:ENSG00000112511(gene)|ensembl:ENSG00000225553(gene)|ensembl:ENST00000374516(transcript)|ensembl:ENST00000427869(transcript)|ensembl:ENST00000454914(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR031202|interpro:IPR040477|mint:O43189|rcsb pdb:2E5P|rcsb pdb:2M0O|rcsb pdb:4HCZ|rcsb pdb:5XFN|rcsb pdb:5XFO|rcsb pdb:5XFP|rcsb pdb:6WAT|rcsb pdb:6WAV|reactome:R-HSA-212300|dip:DIP-34001N|uniprotkb:O43189(identity)|entrezgene/locuslink:5252(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 rogid:8n8g2LqzuOQb8cFC7tE1j/xBvkI9606 intact-crc:99A0984E621AEFA6|rigid:TlyqbJeq5zrIcThDn/ds98akRbQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15910 uniprotkb:O75530 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833042|imex:IM-21659-24 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N|uniprotkb:Q15910(identity)|entrezgene/locuslink:2146(identity)|ddbj/embl/genbank:BC010858(identity) refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:O75530(identity)|entrezgene/locuslink:8726(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 intact-crc:99A0984E621AEFA6|rigid:TlyqbJeq5zrIcThDn/ds98akRbQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15910 uniprotkb:Q96ST3 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 intact:EBI-347218|uniprotkb:Q8N8N4|uniprotkb:Q8NC83|uniprotkb:Q8WV18|uniprotkb:Q96L98|uniprotkb:Q9UFQ1|intact:EBI-28985143|ensembl:ENSP00000353622|ensembl:ENSP00000378402|ensembl:ENSP00000378403|uniprotkb:B2RNS5 psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:sin3a_human(display_long)|uniprotkb:SIN3A(gene name)|psi-mi:SIN3A(display_short)|uniprotkb:Transcriptional corepressor Sin3a(gene name synonym)|uniprotkb:Histone deacetylase complex subunit Sin3a(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833042|imex:IM-21659-24 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N|uniprotkb:Q15910(identity)|entrezgene/locuslink:2146(identity)|ddbj/embl/genbank:BC010858(identity) refseq:XP_006720528.1|ensembl:ENSG00000169375(gene)|ensembl:ENST00000360439(transcript)|ensembl:ENST00000394947(transcript)|ensembl:ENST00000394949(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007568"(aging)|go:"GO:0010817"(regulation of hormone levels)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0031937"(obsolete positive regulation of chromatin silencing)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0051595"(response to methylglyoxal)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1901675"(negative regulation of histone H3-K27 acetylation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR013194(Histone deacetylase interacting)|interpro:IPR031693|interpro:IPR036600|interpro:IPR037969|interpro:IPR039774|mint:Q96ST3|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-427413|reactome:R-HSA-8936459|reactome:R-HSA-9022538|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9022702|rcsb pdb:1PO4|reactome:R-HSA-9615017|reactome:R-HSA-9707564|reactome:R-HSA-983231|refseq:XP_006720529.1|refseq:XP_006720530.1|refseq:NP_001138829.1|refseq:NP_001138830.1|refseq:NP_056292.1|ensembl:ENSP00000353622|ensembl:ENSP00000378402|ensembl:ENSP00000378403|dip:DIP-31515N|uniprotkb:Q96ST3(identity)|entrezgene/locuslink:25942(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 rogid:pO/FziDcMNQRfy6ePi6eNKELXVM9606 intact-crc:99A0984E621AEFA6|rigid:TlyqbJeq5zrIcThDn/ds98akRbQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15910 uniprotkb:Q16576 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833042|imex:IM-21659-24 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N|uniprotkb:Q15910(identity)|entrezgene/locuslink:2146(identity)|ddbj/embl/genbank:BC010858(identity) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|entrezgene/locuslink:5931(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 intact-crc:99A0984E621AEFA6|rigid:TlyqbJeq5zrIcThDn/ds98akRbQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92833 uniprotkb:O75530 intact:EBI-1222720|uniprotkb:Q5U5L5|uniprotkb:A8K9Z6|uniprotkb:B7Z5S5|uniprotkb:Q86X63|uniprotkb:B7Z8L0|ensembl:ENSP00000341280 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 psi-mi:jard2_human(display_long)|uniprotkb:JARID2(gene name)|psi-mi:JARID2(display_short)|uniprotkb:JMJ(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 2(gene name synonym) psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833105|imex:IM-21659-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004964.2|refseq:NP_001253969.1|refseq:XP_005249146.1|refseq:XP_016866323.1|refseq:XP_016866324.1|dip:DIP-45494N|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR036431|mint:Q92833|rcsb pdb:5HYN|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000008083(gene)|ensembl:ENST00000341776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007417"(central nervous system development)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0034721"(histone H3-K4 demethylation, trimethyl-H3-K4-specific)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|uniprotkb:Q92833(identity)|entrezgene/locuslink:3720(identity)|ddbj/embl/genbank:BC046246(identity) refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:O75530(identity)|entrezgene/locuslink:8726(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:G/oMY7WdV7UyQwfT4MOZyET2fS89606 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 intact-crc:05E4795E1B39E219|rigid:0fEXsm4ef2EeMx9Hlq0Ifjf4cJc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92833 uniprotkb:P48643 intact:EBI-1222720|uniprotkb:Q5U5L5|uniprotkb:A8K9Z6|uniprotkb:B7Z5S5|uniprotkb:Q86X63|uniprotkb:B7Z8L0|ensembl:ENSP00000341280 intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8 psi-mi:jard2_human(display_long)|uniprotkb:JARID2(gene name)|psi-mi:JARID2(display_short)|uniprotkb:JMJ(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 2(gene name synonym) psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833105|imex:IM-21659-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004964.2|refseq:NP_001253969.1|refseq:XP_005249146.1|refseq:XP_016866323.1|refseq:XP_016866324.1|dip:DIP-45494N|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR036431|mint:Q92833|rcsb pdb:5HYN|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000008083(gene)|ensembl:ENST00000341776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007417"(central nervous system development)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0034721"(histone H3-K4 demethylation, trimethyl-H3-K4-specific)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|uniprotkb:Q92833(identity)|entrezgene/locuslink:3720(identity)|ddbj/embl/genbank:BC046246(identity) refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N|uniprotkb:P48643(identity)|entrezgene/locuslink:22948(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:G/oMY7WdV7UyQwfT4MOZyET2fS89606 rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606 intact-crc:05E4795E1B39E219|rigid:0fEXsm4ef2EeMx9Hlq0Ifjf4cJc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92833 uniprotkb:Q9BQE3 intact:EBI-1222720|uniprotkb:Q5U5L5|uniprotkb:A8K9Z6|uniprotkb:B7Z5S5|uniprotkb:Q86X63|uniprotkb:B7Z8L0|ensembl:ENSP00000341280 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:jard2_human(display_long)|uniprotkb:JARID2(gene name)|psi-mi:JARID2(display_short)|uniprotkb:JMJ(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 2(gene name synonym) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833105|imex:IM-21659-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004964.2|refseq:NP_001253969.1|refseq:XP_005249146.1|refseq:XP_016866323.1|refseq:XP_016866324.1|dip:DIP-45494N|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR036431|mint:Q92833|rcsb pdb:5HYN|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000008083(gene)|ensembl:ENST00000341776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007417"(central nervous system development)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0034721"(histone H3-K4 demethylation, trimethyl-H3-K4-specific)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|uniprotkb:Q92833(identity)|entrezgene/locuslink:3720(identity)|ddbj/embl/genbank:BC046246(identity) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1|uniprotkb:Q9BQE3(identity)|entrezgene/locuslink:84790(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:G/oMY7WdV7UyQwfT4MOZyET2fS89606 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:05E4795E1B39E219|rigid:0fEXsm4ef2EeMx9Hlq0Ifjf4cJc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92833 uniprotkb:P52434 intact:EBI-1222720|uniprotkb:Q5U5L5|uniprotkb:A8K9Z6|uniprotkb:B7Z5S5|uniprotkb:Q86X63|uniprotkb:B7Z8L0|ensembl:ENSP00000341280 intact:EBI-359505|uniprotkb:P53802|uniprotkb:Q969R0|ensembl:ENSP00000392913|uniprotkb:C9J413|uniprotkb:C9JBJ6|uniprotkb:C9JCU7|uniprotkb:C9JUA8 psi-mi:jard2_human(display_long)|uniprotkb:JARID2(gene name)|psi-mi:JARID2(display_short)|uniprotkb:JMJ(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 2(gene name synonym) psi-mi:rpab3_human(display_long)|uniprotkb:POLR2H(gene name)|psi-mi:POLR2H(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit H(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide(gene name synonym)|uniprotkb:RPB17(gene name synonym)|uniprotkb:RPB8 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833105|imex:IM-21659-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004964.2|refseq:NP_001253969.1|refseq:XP_005249146.1|refseq:XP_016866323.1|refseq:XP_016866324.1|dip:DIP-45494N|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR036431|mint:Q92833|rcsb pdb:5HYN|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000008083(gene)|ensembl:ENST00000341776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007417"(central nervous system development)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0034721"(histone H3-K4 demethylation, trimethyl-H3-K4-specific)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|uniprotkb:Q92833(identity)|entrezgene/locuslink:3720(identity)|ddbj/embl/genbank:BC046246(identity) ensembl:ENSG00000163882(gene)|ensembl:ENST00000456318(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032993"(protein-DNA complex)|interpro:IPR005570(RNA polymerase, Rpb8)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:P52434|rcsb pdb:2F3I|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|refseq:NP_006223.2|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|rcsb pdb:7AE3|reactome:R-HSA-1834949|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-427413|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-203927|refseq:NP_001265627.1|refseq:NP_001265628.1|refseq:NP_001265629.1|refseq:NP_001265644.1|refseq:NP_001265643.1|refseq:XP_006713729.1|refseq:XP_006713730.1|refseq:XP_016862125.1|refseq:XP_016862126.1|dip:DIP-27556N|uniprotkb:P52434(identity)|entrezgene/locuslink:5437(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:G/oMY7WdV7UyQwfT4MOZyET2fS89606 rogid:h7BRWDi8wRbnw/FcFo25bnlVNkE9606 intact-crc:05E4795E1B39E219|rigid:0fEXsm4ef2EeMx9Hlq0Ifjf4cJc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92833 uniprotkb:Q09028 intact:EBI-1222720|uniprotkb:Q5U5L5|uniprotkb:A8K9Z6|uniprotkb:B7Z5S5|uniprotkb:Q86X63|uniprotkb:B7Z8L0|ensembl:ENSP00000341280 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 psi-mi:jard2_human(display_long)|uniprotkb:JARID2(gene name)|psi-mi:JARID2(display_short)|uniprotkb:JMJ(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 2(gene name synonym) psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833105|imex:IM-21659-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004964.2|refseq:NP_001253969.1|refseq:XP_005249146.1|refseq:XP_016866323.1|refseq:XP_016866324.1|dip:DIP-45494N|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR036431|mint:Q92833|rcsb pdb:5HYN|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000008083(gene)|ensembl:ENST00000341776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007417"(central nervous system development)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0034721"(histone H3-K4 demethylation, trimethyl-H3-K4-specific)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|uniprotkb:Q92833(identity)|entrezgene/locuslink:3720(identity)|ddbj/embl/genbank:BC046246(identity) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|entrezgene/locuslink:5928(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:G/oMY7WdV7UyQwfT4MOZyET2fS89606 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 intact-crc:05E4795E1B39E219|rigid:0fEXsm4ef2EeMx9Hlq0Ifjf4cJc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92833 uniprotkb:P25440 intact:EBI-1222720|uniprotkb:Q5U5L5|uniprotkb:A8K9Z6|uniprotkb:B7Z5S5|uniprotkb:Q86X63|uniprotkb:B7Z8L0|ensembl:ENSP00000341280 intact:EBI-2874802|uniprotkb:Q5STC9|uniprotkb:Q6P3U2|uniprotkb:O00699|uniprotkb:B1AZT1|uniprotkb:B0S7P0|uniprotkb:Q969U4|uniprotkb:Q15310|uniprotkb:O00700|uniprotkb:A2AAU0|uniprotkb:Q63HQ9|uniprotkb:Q658Y7|ensembl:ENSP00000363958|ensembl:ENSP00000363964|ensembl:ENSP00000372588|ensembl:ENSP00000382444|ensembl:ENSP00000382445|ensembl:ENSP00000391246|ensembl:ENSP00000399009|ensembl:ENSP00000401791|ensembl:ENSP00000409145|ensembl:ENSP00000449380|ensembl:ENSP00000449609|ensembl:ENSP00000502900 psi-mi:jard2_human(display_long)|uniprotkb:JARID2(gene name)|psi-mi:JARID2(display_short)|uniprotkb:JMJ(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 2(gene name synonym) psi-mi:brd2_human(display_long)|uniprotkb:BRD2(gene name)|psi-mi:BRD2(display_short)|uniprotkb:KIAA9001(gene name synonym)|uniprotkb:RING3(gene name synonym)|uniprotkb:O27.1.1(gene name synonym)|uniprotkb:Really interesting new gene 3 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833105|imex:IM-21659-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004964.2|refseq:NP_001253969.1|refseq:XP_005249146.1|refseq:XP_016866323.1|refseq:XP_016866324.1|dip:DIP-45494N|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR036431|mint:Q92833|rcsb pdb:5HYN|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000008083(gene)|ensembl:ENST00000341776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007417"(central nervous system development)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0034721"(histone H3-K4 demethylation, trimethyl-H3-K4-specific)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|uniprotkb:Q92833(identity)|entrezgene/locuslink:3720(identity)|ddbj/embl/genbank:BC046246(identity) refseq:NP_001278915.1|refseq:NP_001106653.1|refseq:NP_001186384.1|refseq:NP_001186385.1|refseq:NP_005095.1|dip:DIP-60835N|ensembl:ENSG00000204256(gene)|ensembl:ENSG00000215077(gene)|ensembl:ENSG00000234507(gene)|ensembl:ENSG00000234704(gene)|ensembl:ENSG00000235307(gene)|ensembl:ENST00000374825(transcript)|ensembl:ENST00000374831(transcript)|ensembl:ENST00000383108(transcript)|ensembl:ENST00000399528(transcript)|ensembl:ENST00000399529(transcript)|ensembl:ENST00000414731(transcript)|ensembl:ENST00000438194(transcript)|ensembl:ENST00000449085(transcript)|ensembl:ENST00000449118(transcript)|ensembl:ENST00000549126(transcript)|ensembl:ENST00000552587(transcript)|ensembl:ENST00000678250(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016607"(nuclear speck)|go:"GO:0070577"(lysine-acetylated histone binding)|interpro:IPR001487(Bromodomain)|interpro:IPR018359|interpro:IPR027353|interpro:IPR036427|interpro:IPR038336|interpro:IPR043508|interpro:IPR043509|mint:P25440|rcsb pdb:1X0J|rcsb pdb:2DVQ|rcsb pdb:2DVR|rcsb pdb:2DVS|rcsb pdb:2DVV|rcsb pdb:2E3K|rcsb pdb:2G4A|rcsb pdb:2YDW|rcsb pdb:2YEK|rcsb pdb:3AQA|rcsb pdb:3ONI|rcsb pdb:4A9E|rcsb pdb:4A9F|rcsb pdb:4A9H|rcsb pdb:4A9I|rcsb pdb:4A9J|rcsb pdb:4A9M|rcsb pdb:4A9N|rcsb pdb:4A9O|rcsb pdb:4AKN|rcsb pdb:4ALG|rcsb pdb:4ALH|rcsb pdb:4J1P|rcsb pdb:4MR5|rcsb pdb:4QEU|rcsb pdb:4QEV|rcsb pdb:4QEW|rcsb pdb:4UYF|rcsb pdb:4UYG|rcsb pdb:4UYH|rcsb pdb:5BT5|rcsb pdb:5DFB|rcsb pdb:5DFC|rcsb pdb:5DFD|rcsb pdb:5DW1|rcsb pdb:5EK9|rcsb pdb:5HEL|rcsb pdb:5HEM|rcsb pdb:5HEN|rcsb pdb:5HFQ|rcsb pdb:5IBN|rcsb pdb:5IG6|rcsb pdb:5N2L|rcsb pdb:5O38|rcsb pdb:5O39|rcsb pdb:5O3A|rcsb pdb:5O3B|rcsb pdb:5O3C|rcsb pdb:5O3D|rcsb pdb:5O3E|rcsb pdb:5O3F|rcsb pdb:5O3G|rcsb pdb:5O3H|rcsb pdb:5O3I|rcsb pdb:5U5S|rcsb pdb:5U6V|rcsb pdb:5UEW|rcsb pdb:5XHE|rcsb pdb:5XHK|rcsb pdb:6CUI|rcsb pdb:6DB0|rcsb pdb:6DBC|rcsb pdb:6DDI|rcsb pdb:6DDJ|rcsb pdb:4MR6|rcsb pdb:6E6J|rcsb pdb:6FFE|rcsb pdb:6FFF|rcsb pdb:6FFG|rcsb pdb:6I80|rcsb pdb:6I81|rcsb pdb:6JKE|rcsb pdb:6K05|rcsb pdb:6MO7|rcsb pdb:6MO8|rcsb pdb:6MO9|rcsb pdb:6MOA|rcsb pdb:6ONY|rcsb pdb:6SWO|rcsb pdb:6SWP|rcsb pdb:6TQ1|rcsb pdb:6TQ2|rcsb pdb:6U61|rcsb pdb:6U71|rcsb pdb:6U8H|rcsb pdb:6ULQ|rcsb pdb:6ULT|rcsb pdb:6VIY|rcsb pdb:6YTM|rcsb pdb:6Z7F|rcsb pdb:6Z8P|rcsb pdb:6ZB0|rcsb pdb:6ZB1|rcsb pdb:6ZB2|rcsb pdb:7JX7|rcsb pdb:7L6D|rcsb pdb:7NQ5|rcsb pdb:7NQ7|rcsb pdb:7NQ8|rcsb pdb:7NQ9|rcsb pdb:7NQI|rcsb pdb:7NQJ|reactome:R-HSA-8951936|rcsb pdb:6K04|uniprotkb:P25440(identity)|entrezgene/locuslink:6046(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:G/oMY7WdV7UyQwfT4MOZyET2fS89606 rogid:Q3ELpiTZgboufxPDV/bypJZC2oY9606 intact-crc:05E4795E1B39E219|rigid:0fEXsm4ef2EeMx9Hlq0Ifjf4cJc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92833 uniprotkb:Q16576 intact:EBI-1222720|uniprotkb:Q5U5L5|uniprotkb:A8K9Z6|uniprotkb:B7Z5S5|uniprotkb:Q86X63|uniprotkb:B7Z8L0|ensembl:ENSP00000341280 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 psi-mi:jard2_human(display_long)|uniprotkb:JARID2(gene name)|psi-mi:JARID2(display_short)|uniprotkb:JMJ(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 2(gene name synonym) psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833105|imex:IM-21659-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004964.2|refseq:NP_001253969.1|refseq:XP_005249146.1|refseq:XP_016866323.1|refseq:XP_016866324.1|dip:DIP-45494N|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR036431|mint:Q92833|rcsb pdb:5HYN|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000008083(gene)|ensembl:ENST00000341776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007417"(central nervous system development)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0034721"(histone H3-K4 demethylation, trimethyl-H3-K4-specific)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|uniprotkb:Q92833(identity)|entrezgene/locuslink:3720(identity)|ddbj/embl/genbank:BC046246(identity) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|entrezgene/locuslink:5931(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:G/oMY7WdV7UyQwfT4MOZyET2fS89606 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 intact-crc:05E4795E1B39E219|rigid:0fEXsm4ef2EeMx9Hlq0Ifjf4cJc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92833 uniprotkb:Q9Y483 intact:EBI-1222720|uniprotkb:Q5U5L5|uniprotkb:A8K9Z6|uniprotkb:B7Z5S5|uniprotkb:Q86X63|uniprotkb:B7Z8L0|ensembl:ENSP00000341280 intact:EBI-725816|uniprotkb:A6NGQ9|uniprotkb:Q9UES9|uniprotkb:Q9UP40|uniprotkb:A8K2Q3|uniprotkb:B1AKT5|intact:EBI-11028207|uniprotkb:Q96G26|uniprotkb:B1AKT6|ensembl:ENSP00000359321 psi-mi:jard2_human(display_long)|uniprotkb:JARID2(gene name)|psi-mi:JARID2(display_short)|uniprotkb:JMJ(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 2(gene name synonym) psi-mi:mtf2_human(display_long)|uniprotkb:PCL2(gene name synonym)|uniprotkb:Metal-response element DNA-binding protein M96(gene name synonym)|uniprotkb:Metal regulatory transcription factor 2(gene name synonym)|uniprotkb:Polycomb-like protein 2(gene name synonym)|uniprotkb:MTF2(gene name)|psi-mi:MTF2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833105|imex:IM-21659-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004964.2|refseq:NP_001253969.1|refseq:XP_005249146.1|refseq:XP_016866323.1|refseq:XP_016866324.1|dip:DIP-45494N|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR036431|mint:Q92833|rcsb pdb:5HYN|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000008083(gene)|ensembl:ENST00000341776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007417"(central nervous system development)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0034721"(histone H3-K4 demethylation, trimethyl-H3-K4-specific)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|uniprotkb:Q92833(identity)|entrezgene/locuslink:3720(identity)|ddbj/embl/genbank:BC046246(identity) refseq:NP_001157863.1|refseq:NP_001157865.1|refseq:NP_031384.1|refseq:XP_011539318.1|refseq:XP_016856165.1|ensembl:ENSG00000143033(gene)|ensembl:ENST00000370298(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042015|mint:Q9Y483|rcsb pdb:5XFR|reactome:R-HSA-212300|interpro:IPR042014|refseq:NP_001157864.1|uniprotkb:Q9Y483(identity)|entrezgene/locuslink:22823(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:G/oMY7WdV7UyQwfT4MOZyET2fS89606 rogid:Im8E6U/OPb8AEir43AUUDlU6F2o9606 intact-crc:05E4795E1B39E219|rigid:0fEXsm4ef2EeMx9Hlq0Ifjf4cJc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92833 uniprotkb:Q92800 intact:EBI-1222720|uniprotkb:Q5U5L5|uniprotkb:A8K9Z6|uniprotkb:B7Z5S5|uniprotkb:Q86X63|uniprotkb:B7Z8L0|ensembl:ENSP00000341280 intact:EBI-8830732|uniprotkb:B4E3R7|uniprotkb:O43287|uniprotkb:A6NCH6|uniprotkb:Q14459|uniprotkb:Q53XP3|uniprotkb:B4DSS2|uniprotkb:B4DIJ1|uniprotkb:B4DIZ7|ensembl:ENSP00000404658|ensembl:ENSP00000466924 psi-mi:jard2_human(display_long)|uniprotkb:JARID2(gene name)|psi-mi:JARID2(display_short)|uniprotkb:JMJ(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 2(gene name synonym) psi-mi:ezh1_human(display_long)|uniprotkb:ENX-2(gene name synonym)|uniprotkb:Enhancer of zeste homolog 1(gene name synonym)|uniprotkb:KIAA0388(gene name synonym)|uniprotkb:EZH1(gene name)|psi-mi:EZH1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833105|imex:IM-21659-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004964.2|refseq:NP_001253969.1|refseq:XP_005249146.1|refseq:XP_016866323.1|refseq:XP_016866324.1|dip:DIP-45494N|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR036431|mint:Q92833|rcsb pdb:5HYN|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000008083(gene)|ensembl:ENST00000341776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007417"(central nervous system development)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0034721"(histone H3-K4 demethylation, trimethyl-H3-K4-specific)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|uniprotkb:Q92833(identity)|entrezgene/locuslink:3720(identity)|ddbj/embl/genbank:BC046246(identity) refseq:NP_001308008.1|refseq:NP_001308010.1|refseq:NP_001308011.1|refseq:NP_001982.2|dip:DIP-58580N|ensembl:ENSG00000108799(gene)|ensembl:ENST00000428826(transcript)|ensembl:ENST00000592743(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0021766"(hippocampus development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0031507"(heterochromatin assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR021654|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR032926|interpro:IPR041343|interpro:IPR041355|interpro:IPR044438|mint:Q92800|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|uniprotkb:Q92800(identity)|entrezgene/locuslink:2145(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:G/oMY7WdV7UyQwfT4MOZyET2fS89606 rogid:qp3eqBCgiaoA6VSSyqpW1d9YKN49606 intact-crc:05E4795E1B39E219|rigid:0fEXsm4ef2EeMx9Hlq0Ifjf4cJc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92833 uniprotkb:Q15910 intact:EBI-1222720|uniprotkb:Q5U5L5|uniprotkb:A8K9Z6|uniprotkb:B7Z5S5|uniprotkb:Q86X63|uniprotkb:B7Z8L0|ensembl:ENSP00000341280 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 psi-mi:jard2_human(display_long)|uniprotkb:JARID2(gene name)|psi-mi:JARID2(display_short)|uniprotkb:JMJ(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 2(gene name synonym) psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833105|imex:IM-21659-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004964.2|refseq:NP_001253969.1|refseq:XP_005249146.1|refseq:XP_016866323.1|refseq:XP_016866324.1|dip:DIP-45494N|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR036431|mint:Q92833|rcsb pdb:5HYN|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000008083(gene)|ensembl:ENST00000341776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007417"(central nervous system development)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0034721"(histone H3-K4 demethylation, trimethyl-H3-K4-specific)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|uniprotkb:Q92833(identity)|entrezgene/locuslink:3720(identity)|ddbj/embl/genbank:BC046246(identity) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N|uniprotkb:Q15910(identity)|entrezgene/locuslink:2146(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:G/oMY7WdV7UyQwfT4MOZyET2fS89606 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 intact-crc:05E4795E1B39E219|rigid:0fEXsm4ef2EeMx9Hlq0Ifjf4cJc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92833 uniprotkb:Q15022 intact:EBI-1222720|uniprotkb:Q5U5L5|uniprotkb:A8K9Z6|uniprotkb:B7Z5S5|uniprotkb:Q86X63|uniprotkb:B7Z8L0|ensembl:ENSP00000341280 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 psi-mi:jard2_human(display_long)|uniprotkb:JARID2(gene name)|psi-mi:JARID2(display_short)|uniprotkb:JMJ(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 2(gene name synonym) psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833105|imex:IM-21659-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004964.2|refseq:NP_001253969.1|refseq:XP_005249146.1|refseq:XP_016866323.1|refseq:XP_016866324.1|dip:DIP-45494N|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR036431|mint:Q92833|rcsb pdb:5HYN|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000008083(gene)|ensembl:ENST00000341776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007417"(central nervous system development)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0034721"(histone H3-K4 demethylation, trimethyl-H3-K4-specific)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|uniprotkb:Q92833(identity)|entrezgene/locuslink:3720(identity)|ddbj/embl/genbank:BC046246(identity) dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:Q15022(identity)|entrezgene/locuslink:23512(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:G/oMY7WdV7UyQwfT4MOZyET2fS89606 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 intact-crc:05E4795E1B39E219|rigid:0fEXsm4ef2EeMx9Hlq0Ifjf4cJc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92833 uniprotkb:Q6ZN18 intact:EBI-1222720|uniprotkb:Q5U5L5|uniprotkb:A8K9Z6|uniprotkb:B7Z5S5|uniprotkb:Q86X63|uniprotkb:B7Z8L0|ensembl:ENSP00000341280 intact:EBI-743256|ensembl:ENSP00000381840|uniprotkb:Q59FS5|uniprotkb:Q6ZN62|uniprotkb:Q96BG3 psi-mi:jard2_human(display_long)|uniprotkb:JARID2(gene name)|psi-mi:JARID2(display_short)|uniprotkb:JMJ(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 2(gene name synonym) psi-mi:aebp2_human(display_long)|uniprotkb:Adipocyte enhancer-binding protein 2(gene name synonym)|uniprotkb:AEBP2(gene name)|psi-mi:AEBP2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833105|imex:IM-21659-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004964.2|refseq:NP_001253969.1|refseq:XP_005249146.1|refseq:XP_016866323.1|refseq:XP_016866324.1|dip:DIP-45494N|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR036431|mint:Q92833|rcsb pdb:5HYN|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000008083(gene)|ensembl:ENST00000341776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007417"(central nervous system development)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0034721"(histone H3-K4 demethylation, trimethyl-H3-K4-specific)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|uniprotkb:Q92833(identity)|entrezgene/locuslink:3720(identity)|ddbj/embl/genbank:BC046246(identity) ensembl:ENSG00000139154(gene)|interpro:IPR036236|ensembl:ENST00000398864(transcript)|go:"GO:0000785"(chromatin)|mint:Q6ZN18|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001107648.1|refseq:NP_694939.2|rcsb pdb:5WAI|rcsb pdb:5Y0U|rcsb pdb:5Y1U|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|reactome:R-HSA-3214841|refseq:NP_001253972.1|dip:DIP-58581N|uniprotkb:Q6ZN18(identity)|entrezgene/locuslink:121536(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:G/oMY7WdV7UyQwfT4MOZyET2fS89606 rogid:mOY+NOTaqJlXjW8v6D3YPnfnfBU9606 intact-crc:05E4795E1B39E219|rigid:0fEXsm4ef2EeMx9Hlq0Ifjf4cJc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JN0 uniprotkb:Q13363 intact:EBI-746045|uniprotkb:Q9H945|uniprotkb:Q9Y457|ensembl:ENSP00000348298|ensembl:ENSP00000360138|ensembl:ENSP00000360144|ensembl:ENSP00000501560|ensembl:ENSP00000501639|ensembl:ENSP00000502633|intact:EBI-8833163|uniprotkb:D3DR47|uniprotkb:Q5VW16|uniprotkb:Q7Z723|uniprotkb:Q86T32|uniprotkb:Q86T33|uniprotkb:Q8N3L6|uniprotkb:Q8N655 intact:EBI-908846|uniprotkb:Q4W5N3|uniprotkb:Q7Z2Q5|ensembl:ENSP00000290921 psi-mi:lcor_human(display_long)|uniprotkb:LCOR(gene name)|psi-mi:LCOR(display_short)|uniprotkb:C10orf12(gene name synonym)|uniprotkb:KIAA1795(gene name synonym)|uniprotkb:MLR2(gene name synonym)|uniprotkb:Mblk1-related protein 2(gene name synonym) psi-mi:ctbp1_human(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833173|imex:IM-21659-26 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196233(gene)|ensembl:ENST00000356016(transcript)|ensembl:ENST00000371097(transcript)|ensembl:ENST00000371103(transcript)|ensembl:ENST00000675471(transcript)|ensembl:ENST00000675537(transcript)|ensembl:ENST00000675971(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|mint:Q96JN0|rcsb pdb:2COB|refseq:NP_001164236.1|refseq:NP_001164237.1|refseq:NP_115816.2|refseq:XP_016872275.1|refseq:XP_016872276.1|refseq:XP_016872277.1|refseq:NP_001333445.1|uniprotkb:Q96JN0(identity)|entrezgene/locuslink:84458(identity)|ddbj/embl/genbank:BC053359(identity) refseq:NP_001012632.1|refseq:NP_001319.1|refseq:XP_016863253.1|refseq:XP_016863254.1|refseq:XP_016863255.1|refseq:XP_016863256.1|dip:DIP-24245N|ensembl:ENSG00000159692(gene)|ensembl:ENST00000290921(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019079"(viral genome replication)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:Q13363|rcsb pdb:1MX3|rcsb pdb:4LCE|rcsb pdb:4U6Q|rcsb pdb:4U6S|rcsb pdb:6CDF|rcsb pdb:6CDR|rcsb pdb:6V89|rcsb pdb:6V8A|rcsb pdb:7KWM|reactome:R-HSA-3769402|reactome:R-HSA-3899300|reactome:R-HSA-4641265|reactome:R-HSA-5339700|uniprotkb:Q13363(identity)|entrezgene/locuslink:1487(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:cOnk6EDDff86yaG1uG+dxEQ1Z689606 rogid:hhYGrtcr0oAQW5x5LfNmxfuRNj49606 intact-crc:2D3F6EE4B698BE63|rigid:GQdrcGH0m3c0cFDwc6XBPj5kMjY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JN0 uniprotkb:Q9BQE3 intact:EBI-746045|uniprotkb:Q9H945|uniprotkb:Q9Y457|ensembl:ENSP00000348298|ensembl:ENSP00000360138|ensembl:ENSP00000360144|ensembl:ENSP00000501560|ensembl:ENSP00000501639|ensembl:ENSP00000502633|intact:EBI-8833163|uniprotkb:D3DR47|uniprotkb:Q5VW16|uniprotkb:Q7Z723|uniprotkb:Q86T32|uniprotkb:Q86T33|uniprotkb:Q8N3L6|uniprotkb:Q8N655 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:lcor_human(display_long)|uniprotkb:LCOR(gene name)|psi-mi:LCOR(display_short)|uniprotkb:C10orf12(gene name synonym)|uniprotkb:KIAA1795(gene name synonym)|uniprotkb:MLR2(gene name synonym)|uniprotkb:Mblk1-related protein 2(gene name synonym) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833173|imex:IM-21659-26 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196233(gene)|ensembl:ENST00000356016(transcript)|ensembl:ENST00000371097(transcript)|ensembl:ENST00000371103(transcript)|ensembl:ENST00000675471(transcript)|ensembl:ENST00000675537(transcript)|ensembl:ENST00000675971(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|mint:Q96JN0|rcsb pdb:2COB|refseq:NP_001164236.1|refseq:NP_001164237.1|refseq:NP_115816.2|refseq:XP_016872275.1|refseq:XP_016872276.1|refseq:XP_016872277.1|refseq:NP_001333445.1|uniprotkb:Q96JN0(identity)|entrezgene/locuslink:84458(identity)|ddbj/embl/genbank:BC053359(identity) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1|uniprotkb:Q9BQE3(identity)|entrezgene/locuslink:84790(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:cOnk6EDDff86yaG1uG+dxEQ1Z689606 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:2D3F6EE4B698BE63|rigid:GQdrcGH0m3c0cFDwc6XBPj5kMjY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JN0 uniprotkb:P28799 intact:EBI-746045|uniprotkb:Q9H945|uniprotkb:Q9Y457|ensembl:ENSP00000348298|ensembl:ENSP00000360138|ensembl:ENSP00000360144|ensembl:ENSP00000501560|ensembl:ENSP00000501639|ensembl:ENSP00000502633|intact:EBI-8833163|uniprotkb:D3DR47|uniprotkb:Q5VW16|uniprotkb:Q7Z723|uniprotkb:Q86T32|uniprotkb:Q86T33|uniprotkb:Q8N3L6|uniprotkb:Q8N655 intact:EBI-747754|uniprotkb:P23781|uniprotkb:P23782|uniprotkb:P23783|uniprotkb:P23784|uniprotkb:Q9BWE7|uniprotkb:Q9UCH0|ensembl:ENSP00000053867|uniprotkb:Q53Y88|uniprotkb:Q540U8|uniprotkb:D3DX55|uniprotkb:Q53HQ8|uniprotkb:Q9H8S1 psi-mi:lcor_human(display_long)|uniprotkb:LCOR(gene name)|psi-mi:LCOR(display_short)|uniprotkb:C10orf12(gene name synonym)|uniprotkb:KIAA1795(gene name synonym)|uniprotkb:MLR2(gene name synonym)|uniprotkb:Mblk1-related protein 2(gene name synonym) psi-mi:grn_human(display_long)|uniprotkb:Proepithelin(gene name synonym)|uniprotkb:GRN(gene name)|psi-mi:GRN(display_short)|uniprotkb:Acrogranin(gene name synonym)|uniprotkb:Epithelin precursor(gene name synonym)|uniprotkb:Glycoprotein of 88 Kda(gene name synonym)|uniprotkb:Granulin precursor(gene name synonym)|uniprotkb:PC cell-derived growth factor(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833173|imex:IM-21659-26 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196233(gene)|ensembl:ENST00000356016(transcript)|ensembl:ENST00000371097(transcript)|ensembl:ENST00000371103(transcript)|ensembl:ENST00000675471(transcript)|ensembl:ENST00000675537(transcript)|ensembl:ENST00000675971(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|mint:Q96JN0|rcsb pdb:2COB|refseq:NP_001164236.1|refseq:NP_001164237.1|refseq:NP_115816.2|refseq:XP_016872275.1|refseq:XP_016872276.1|refseq:XP_016872277.1|refseq:NP_001333445.1|uniprotkb:Q96JN0(identity)|entrezgene/locuslink:84458(identity)|ddbj/embl/genbank:BC053359(identity) refseq:NP_002078.1|ensembl:ENSG00000030582(gene)|ensembl:ENST00000053867(transcript)|go:"GO:0002265"(astrocyte activation involved in immune response)|go:"GO:0002282"(microglial cell activation involved in immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007040"(lysosome organization)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007165"(signal transduction)|go:"GO:0008083"(growth factor activity)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048680"(positive regulation of axon regeneration)|refseq:XP_005257310.1|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106016"(positive regulation of inflammatory response to wounding)|go:"GO:1900426"(positive regulation of defense response to bacterium)|go:"GO:1902564"(negative regulation of neutrophil activation)|go:"GO:1903334"(positive regulation of protein folding)|go:"GO:1903979"(negative regulation of microglial cell activation)|go:"GO:1905247"(positive regulation of aspartic-type peptidase activity)|go:"GO:1905673"(positive regulation of lysosome organization)|interpro:IPR000118(Granulin)|interpro:IPR037277|interpro:IPR039036|mint:P28799|rcsb pdb:1G26|rcsb pdb:2JYE|rcsb pdb:2JYT|rcsb pdb:2JYU|rcsb pdb:2JYV|rcsb pdb:6NUG|reactome:R-HSA-6798695|dip:DIP-41742N|uniprotkb:P28799(identity)|entrezgene/locuslink:2896(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:cOnk6EDDff86yaG1uG+dxEQ1Z689606 rogid:SaujQCj7wHfPYunGzgTgG+jQgA89606 intact-crc:2D3F6EE4B698BE63|rigid:GQdrcGH0m3c0cFDwc6XBPj5kMjY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JN0 uniprotkb:P56545 intact:EBI-746045|uniprotkb:Q9H945|uniprotkb:Q9Y457|ensembl:ENSP00000348298|ensembl:ENSP00000360138|ensembl:ENSP00000360144|ensembl:ENSP00000501560|ensembl:ENSP00000501639|ensembl:ENSP00000502633|intact:EBI-8833163|uniprotkb:D3DR47|uniprotkb:Q5VW16|uniprotkb:Q7Z723|uniprotkb:Q86T32|uniprotkb:Q86T33|uniprotkb:Q8N3L6|uniprotkb:Q8N655 intact:EBI-741533|uniprotkb:O43449|uniprotkb:Q5SQP7|uniprotkb:Q69YI3|uniprotkb:Q86SV0|uniprotkb:Q9H2T8|uniprotkb:A8K2X5|ensembl:ENSP00000338615|ensembl:ENSP00000410474|ensembl:ENSP00000434630|ensembl:ENSP00000436285|uniprotkb:D3DRF5|uniprotkb:Q8IY44|intact:EBI-11742664 psi-mi:lcor_human(display_long)|uniprotkb:LCOR(gene name)|psi-mi:LCOR(display_short)|uniprotkb:C10orf12(gene name synonym)|uniprotkb:KIAA1795(gene name synonym)|uniprotkb:MLR2(gene name synonym)|uniprotkb:Mblk1-related protein 2(gene name synonym) psi-mi:ctbp2_human(display_long)|uniprotkb:CTBP2(gene name)|psi-mi:CTBP2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833173|imex:IM-21659-26 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196233(gene)|ensembl:ENST00000356016(transcript)|ensembl:ENST00000371097(transcript)|ensembl:ENST00000371103(transcript)|ensembl:ENST00000675471(transcript)|ensembl:ENST00000675537(transcript)|ensembl:ENST00000675971(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|mint:Q96JN0|rcsb pdb:2COB|refseq:NP_001164236.1|refseq:NP_001164237.1|refseq:NP_115816.2|refseq:XP_016872275.1|refseq:XP_016872276.1|refseq:XP_016872277.1|refseq:NP_001333445.1|uniprotkb:Q96JN0(identity)|entrezgene/locuslink:84458(identity)|ddbj/embl/genbank:BC053359(identity) refseq:NP_001077383.1|refseq:NP_001320.1|refseq:NP_073713.2|refseq:NP_001307943.1|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:P56545|rcsb pdb:2OME|rcsb pdb:4LCJ|rcsb pdb:6WKW|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-9662360|go:"GO:0048386"(positive regulation of retinoic acid receptor signaling pathway)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0098684"(photoreceptor ribbon synapse)|ensembl:ENSG00000175029(gene)|ensembl:ENST00000337195(transcript)|ensembl:ENST00000411419(transcript)|ensembl:ENST00000494626(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|ensembl:ENST00000531469(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019079"(viral genome replication)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|refseq:XP_011537653.1|refseq:XP_011537655.1|refseq:XP_011537656.1|refseq:XP_011537657.1|refseq:NP_001307941.1|refseq:NP_001307942.1|refseq:XP_005269618.1|refseq:XP_005269621.1|refseq:XP_005269624.1|refseq:XP_005269625.1|refseq:XP_005269626.1|refseq:XP_005269628.1|refseq:XP_005269629.1|refseq:NP_001277143.1|refseq:NP_001277144.1|refseq:XP_006717705.1|refseq:XP_016871245.1|refseq:XP_016871246.1|dip:DIP-42104N|refseq:XP_011537651.1|uniprotkb:P56545(identity)|entrezgene/locuslink:1488(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:cOnk6EDDff86yaG1uG+dxEQ1Z689606 rogid:6sKiqjMRW/ViEvTbQJoaUjgvZtc9606 intact-crc:2D3F6EE4B698BE63|rigid:GQdrcGH0m3c0cFDwc6XBPj5kMjY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:O43823 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-1237481|ensembl:ENSP00000269701 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:akap8_human(display_long)|uniprotkb:AKAP8(gene name)|psi-mi:AKAP8(display_short)|uniprotkb:AKAP95(gene name synonym)|uniprotkb:A-kinase anchor protein 95 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_005849.1|dip:DIP-38194N|ensembl:ENSG00000105127(gene)|ensembl:ENST00000269701(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001939"(female pronucleus)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0033127"(regulation of histone phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044839"(cell cycle G2/M phase transition)|go:"GO:0045087"(innate immune response)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|interpro:IPR007071("A-kinase anchoring protein 95 (AKAP95)")|interpro:IPR034736|mint:O43823|go:"GO:0051059"(NF-kappaB binding)|uniprotkb:O43823(identity)|entrezgene/locuslink:10270(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:VtRlGSvkRqrzAcnq2Fj6fToZifY9606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:P62191 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-357598|uniprotkb:P49014|uniprotkb:Q03527|uniprotkb:Q6IAW0|uniprotkb:Q96AZ3|ensembl:ENSP00000261303|uniprotkb:Q6NW36|uniprotkb:B4DR63 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:prs4_human(display_long)|uniprotkb:PSMC1(gene name)|psi-mi:PSMC1(display_short)|uniprotkb:26S proteasome AAA-ATPase subunit RPT2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_002793.2|ensembl:ENST00000261303(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|ensembl:ENSG00000100764(gene)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|mint:P62191|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFQ|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-8852276|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|refseq:NP_001317141.1|refseq:XP_016876959.1|uniprotkb:P62191(identity)|entrezgene/locuslink:5700(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:oGEtU7Cv0qversbD3WQgAo5H9pM9606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:O00487 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-722193|uniprotkb:O00176|uniprotkb:B3KNW2|ensembl:ENSP00000386541 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:psde_human(display_long)|uniprotkb:26S proteasome regulatory subunit RPN11(gene name synonym)|uniprotkb:26S proteasome-associated PAD1 homolog 1(gene name synonym)|uniprotkb:PSMD14(gene name)|psi-mi:PSMD14(display_short)|uniprotkb:POH1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_005796.1|ensembl:ENSG00000115233(gene)|ensembl:ENST00000409682(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070628"(proteasome binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR035299|interpro:IPR037518|mint:O00487|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|uniprotkb:O00487(identity)|entrezgene/locuslink:10213(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:pSM+755ZbQisR5S0ZivcYBu9Bc49606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:Q13263 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-78139|uniprotkb:O00677|ensembl:ENSP00000253024|uniprotkb:Q7Z632|uniprotkb:Q93040|uniprotkb:Q96IM1 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:tif1b_human(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6QAJ|rcsb pdb:6QU1|reactome:R-HSA-212436|reactome:R-HSA-3899300|reactome:R-HSA-9609690|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q13263|rcsb pdb:1FP0|rcsb pdb:2RO1|rcsb pdb:2YVR|rcsb pdb:6H3A|rcsb pdb:6I9H|refseq:NP_005753.1|dip:DIP-30891N|uniprotkb:Q13263(identity)|entrezgene/locuslink:10155(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:Q9Y4W2 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-1051591|uniprotkb:Q5JXQ0|uniprotkb:Q8TEN5|uniprotkb:Q9H9V5|uniprotkb:A9X410|ensembl:ENSP00000363944 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:las1l_human(display_long)|uniprotkb:LAS1L(gene name)|psi-mi:LAS1L(display_short)|uniprotkb:Protein LAS1 homolog(gene name synonym)|uniprotkb:MSTP060(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_001164120.1|refseq:NP_001164121.1|refseq:NP_112483.1|ensembl:ENSG00000001497(gene)|ensembl:ENST00000374811(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090730"(Las1 complex)|interpro:IPR007174(Las1-like)|mint:Q9Y4W2|reactome:R-HSA-6791226|uniprotkb:Q9Y4W2(identity)|entrezgene/locuslink:81887(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:1TTE2TCMIwczNaT2SSMLioLkALA9606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:P22087 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-358318|uniprotkb:O75259|uniprotkb:Q6IAT5|uniprotkb:Q9UPI6|ensembl:ENSP00000221801|ensembl:ENSP00000487390|uniprotkb:B5BUE8 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:fbrl_human(display_long)|uniprotkb:FBL(gene name)|psi-mi:FBL(display_short)|uniprotkb:FIB1(gene name synonym)|uniprotkb:FLRN(gene name synonym)|uniprotkb:Histone-glutamine methyltransferase(gene name synonym)|uniprotkb:34 kDa nucleolar scleroderma antigen(gene name synonym)|uniprotkb:U6 snRNA 2'-O-methyltransferase fibrillarin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_001427.2|ensembl:ENSG00000105202(gene)|ensembl:ENSG00000280548(gene)|ensembl:ENST00000221801(transcript)|ensembl:ENST00000625241(transcript)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001650"(fibrillar center)|go:"GO:0001651"(dense fibrillar component)|go:"GO:0001652"(granular component)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0008649"(rRNA methyltransferase activity)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0031167"(rRNA methylation)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0048254"(snoRNA localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990258"(histone glutamine methylation)|go:"GO:1990259"(histone-glutamine methyltransferase activity)|interpro:IPR000692(Fibrillarin)|interpro:IPR020813|interpro:IPR029063|mint:P22087|rcsb pdb:2IPX|reactome:R-HSA-6790901|reactome:R-HSA-6791226|dip:DIP-27569N|uniprotkb:P22087(identity)|entrezgene/locuslink:2091(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:8m8FDRSxGNKNXpJMcWWbcHL3uss9606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:P62195 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-357745|uniprotkb:O35051|uniprotkb:O43208|uniprotkb:P52915|uniprotkb:P47210|uniprotkb:P52916|uniprotkb:A8K763|uniprotkb:A8K3Z3|ensembl:ENSP00000310572 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:prs8_human(display_long)|uniprotkb:PSMC5(gene name)|psi-mi:PSMC5(display_short)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 5(gene name synonym)|uniprotkb:Proteasome subunit p45(gene name synonym)|uniprotkb:p45/SUG(gene name synonym)|uniprotkb:Thyroid hormone receptor-interacting protein 1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_001186092.1|refseq:NP_002796.4|reactome:R-HSA-195253|ensembl:ENSG00000087191(gene)|ensembl:ENST00000310144(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031531"(thyrotropin-releasing hormone receptor binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|mint:P62195|rcsb pdb:2KRK|rcsb pdb:3KW6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-36645N|uniprotkb:P62195(identity)|entrezgene/locuslink:5705(identity) psi-mi:"MI:0469"(intact) - crc64:29C6410C4A85A7F7 figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:zgUTOX/O4m86U/Nf+pnT7u0m0gY9606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:Q9ULX6 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-357530|uniprotkb:O94792|uniprotkb:Q96J58|uniprotkb:Q9NRQ0|uniprotkb:Q9UGM0|uniprotkb:B5BU90|uniprotkb:B4DJ74|ensembl:ENSP00000380557 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:akp8l_human(display_long)|uniprotkb:AKAP8L(gene name)|psi-mi:AKAP8L(display_short)|uniprotkb:HRIHFB2018(orf name)|uniprotkb:NAKAP95(gene name synonym)|uniprotkb:Neighbor of A-kinase-anchoring protein 95(gene name synonym)|uniprotkb:Homologous to AKAP95 protein(gene name synonym)|uniprotkb:Helicase A-binding protein 95(gene name synonym)|uniprotkb:NAKAP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_001278407.1|refseq:NP_055186.3|dip:DIP-27541N|ensembl:ENSG00000011243(gene)|ensembl:ENST00000397410(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0033127"(regulation of histone phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044839"(cell cycle G2/M phase transition)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007071("A-kinase anchoring protein 95 (AKAP95)")|interpro:IPR034736|mint:Q9ULX6|uniprotkb:Q9ULX6(identity)|entrezgene/locuslink:26993(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:SAs8jxuWxLOiWN/TRyjVvr5m/5Y9606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:O75190 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-1053164|uniprotkb:A4D232|uniprotkb:O95806|uniprotkb:A8KAG0|uniprotkb:B4DN73|uniprotkb:E9PCZ2|uniprotkb:Q53EN8|uniprotkb:Q59EF2|uniprotkb:Q6FIC8|uniprotkb:Q75MA2|uniprotkb:Q9UIK6|uniprotkb:A8K7D8|ensembl:ENSP00000262177 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:dnjb6_human(display_long)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:MSJ-1(gene name synonym)|uniprotkb:HHDJ1(gene name synonym)|uniprotkb:DNAJB6(gene name)|psi-mi:DNAJB6(display_short)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:MSJ1(gene name synonym)|uniprotkb:MRJ(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_005485.1|refseq:NP_490647.1|ensembl:ENSG00000105993(gene)|ensembl:ENST00000262177(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0060715"(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:"GO:0060717"(chorion development)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:O75190|rcsb pdb:6U3R|rcsb pdb:6U3S|rcsb pdb:7JSQ|reactome:R-HSA-3371453|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|uniprotkb:O75190(identity)|entrezgene/locuslink:10049(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:6X99Uu2SBlHsGCv61ZbwSz4LRp89606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:Q9NVI1 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-1013291|uniprotkb:Q96JN1|uniprotkb:Q96ST0|uniprotkb:Q9BT96|uniprotkb:A5YMH4|uniprotkb:A6NJZ0|uniprotkb:A4ZVE4|ensembl:ENSP00000310842 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:fanci_human(display_long)|uniprotkb:FANCI(gene name)|psi-mi:FANCI(display_short)|uniprotkb:KIAA1794(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:XP_011520058.1|refseq:XP_011520059.1|refseq:XP_011520066.1|refseq:NP_001106849.1|refseq:NP_060663.2|dip:DIP-29381N|ensembl:ENSG00000140525(gene)|ensembl:ENST00000310775(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0070182"(DNA polymerase binding)|interpro:IPR026171|interpro:IPR029305|interpro:IPR029308|interpro:IPR029310|interpro:IPR029312|interpro:IPR029313|interpro:IPR029314|interpro:IPR029315|mint:Q9NVI1|rcsb pdb:6VAA|rcsb pdb:6VAD|rcsb pdb:6VAE|rcsb pdb:6VAF|rcsb pdb:7AY1|reactome:R-HSA-6783310|reactome:R-HSA-6796648|uniprotkb:Q9NVI1(identity)|entrezgene/locuslink:55215(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:yJJMHIBOVPDIQcCBJ19DGitg3VA9606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:P20618 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-372273|uniprotkb:Q9BWA8|ensembl:ENSP00000262193|uniprotkb:B5BU76 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:psb1_human(display_long)|uniprotkb:PSMB1(gene name)|psi-mi:PSMB1(display_short)|uniprotkb:PSC5(gene name synonym)|uniprotkb:Proteasome component C5(gene name synonym)|uniprotkb:Macropain subunit C5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C5(gene name synonym)|uniprotkb:Proteasome gamma chain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) ensembl:ENSG00000008018(gene)|ensembl:ENST00000262193(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|mint:P20618|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|refseq:NP_002784.1|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M2B|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5LF1|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4608870|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-983168|reactome:R-HSA-9604323|dip:DIP-31193N|uniprotkb:P20618(identity)|entrezgene/locuslink:5689(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:DfIS480BUnqbXus9/KoojdkWgw09606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:P28070 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-603350|uniprotkb:P31148|uniprotkb:Q5SZS5|uniprotkb:Q969L6|uniprotkb:B2R9L3|uniprotkb:Q6IBI4|ensembl:ENSP00000290541 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:psb4_human(display_long)|uniprotkb:PSMB4(gene name)|psi-mi:PSMB4(display_short)|uniprotkb:Macropain beta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex beta chain(gene name synonym)|uniprotkb:Proteasome chain 3(gene name synonym)|uniprotkb:26 kDa prosomal protein(gene name synonym)|uniprotkb:PROS26(gene name synonym)|uniprotkb:Proteasome beta chain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_002787.2|dip:DIP-33844N|ensembl:ENSG00000159377(gene)|ensembl:ENST00000290541(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR016295(Proteasome endopeptidase complex, beta subunit)|interpro:IPR023333|interpro:IPR029055|mint:P28070|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|uniprotkb:P28070(identity)|entrezgene/locuslink:5692(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:drR+ktPXQK9ep6hs7OYb5SmQnXU9606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:Q99436 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-603319|uniprotkb:Q96AG8|uniprotkb:Q9BWA7|uniprotkb:B4E0P1|uniprotkb:Q5TBG6|ensembl:ENSP00000259457 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:psb7_human(display_long)|uniprotkb:PSMB7(gene name)|psi-mi:PSMB7(display_short)|uniprotkb:Proteasome subunit Z(gene name synonym)|uniprotkb:Macropain chain Z(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain Z(gene name synonym)|uniprotkb:Z(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_002790.1|dip:DIP-33843N|ensembl:ENSG00000136930(gene)|ensembl:ENST00000259457(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016604"(nuclear body)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR024689|interpro:IPR029055|interpro:IPR035216|mint:Q99436|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|uniprotkb:Q99436(identity)|entrezgene/locuslink:5695(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:w880QftOor3RdaGvhCup7apz2OM9606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:O14818 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-603272|uniprotkb:Q9BR53|uniprotkb:Q9H4K5|uniprotkb:Q9UEU8|uniprotkb:B2R515|uniprotkb:Q5JXJ2|ensembl:ENSP00000359910 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:psa7_human(display_long)|uniprotkb:PSMA7(gene name)|psi-mi:PSMA7(display_short)|uniprotkb:Proteasome subunit RC6-1(gene name synonym)|uniprotkb:Proteasome subunit XAPC7(gene name synonym)|uniprotkb:HSPC(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_002783.1|dip:DIP-29363N|ensembl:ENSG00000101182(gene)|ensembl:ENST00000370873(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098794"(postsynapse)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035190|mint:O14818|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|uniprotkb:O14818(identity)|entrezgene/locuslink:5688(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:J1M+b+VK02BAn2OnZISjjlmO8dc9606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:Q96IX5 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-954033|ensembl:ENSP00000311245|ensembl:ENSP00000337705|ensembl:ENSP00000358826|ensembl:ENSP00000358830|ensembl:ENSP00000358840|uniprotkb:B2R4N2|uniprotkb:D3DR92 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:atpmk_human(display_long)|uniprotkb:ATP5MK(gene name)|psi-mi:ATP5MK(display_short)|uniprotkb:ATP synthase membrane subunit DAPIT, mitochondrial(gene name synonym)|uniprotkb:ATP5MD(gene name synonym)|uniprotkb:DAPIT(gene name synonym)|uniprotkb:Diabetes-associated protein in insulin-sensitive tissues(gene name synonym)|uniprotkb:HCV F-transactivated protein 2(gene name synonym)|uniprotkb:HCVFTP2(gene name synonym)|uniprotkb:USMG5(gene name synonym)|uniprotkb:Up-regulated during skeletal muscle growth protein 5(gene name synonym)|uniprotkb:PD04912(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) ensembl:ENSG00000173915(gene)|ensembl:ENST00000309579(transcript)|ensembl:ENST00000337003(transcript)|ensembl:ENST00000369811(transcript)|ensembl:ENST00000369815(transcript)|ensembl:ENST00000369825(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR009125(DAPIT)|mint:Q96IX5|refseq:NP_001193355.1|refseq:NP_001193356.1|refseq:NP_116136.1|uniprotkb:Q96IX5(identity)|entrezgene/locuslink:84833(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:7ClNWlgeH39kD7E6oiQdkuj7Hag9606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:Q13200 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-357648|uniprotkb:B4DX07|uniprotkb:B4DXY1|uniprotkb:E7EW34|uniprotkb:E9PCS3|uniprotkb:Q12932|uniprotkb:Q15321|uniprotkb:Q96I12|ensembl:ENSP00000310129|uniprotkb:Q53XQ4 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:psmd2_human(display_long)|uniprotkb:PSMD2(gene name)|psi-mi:PSMD2(display_short)|uniprotkb:TRAP2(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN1(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S2(gene name synonym)|uniprotkb:26S proteasome subunit p97(gene name synonym)|uniprotkb:Tumor necrosis factor type 1 receptor-associated protein 2(gene name synonym)|uniprotkb:Protein 55.11(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_001265637.1|refseq:NP_001265638.1|refseq:NP_002799.3|ensembl:ENSG00000175166(gene)|ensembl:ENST00000310118(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040892|interpro:IPR041433|mint:Q13200|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|rcsb pdb:5VHM|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|rcsb pdb:6MSB|rcsb pdb:6MSD|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-5668541|dip:DIP-38204N|uniprotkb:Q13200(identity)|entrezgene/locuslink:5708(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:wujS1i4Gs3gWNinOey4oKsshA+g9606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:P17980 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-359720|uniprotkb:Q3B757|ensembl:ENSP00000298852|ensembl:ENSP00000481029|uniprotkb:Q3B865|uniprotkb:Q53HU5|uniprotkb:Q6GPG8|uniprotkb:Q6IBS1|uniprotkb:Q96HD3|uniprotkb:B2R8V1 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:prs6a_human(display_long)|uniprotkb:PSMC3(gene name)|psi-mi:PSMC3(display_short)|uniprotkb:TBP1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 3(gene name synonym)|uniprotkb:Tat-binding protein 1(gene name synonym)|uniprotkb:Proteasome subunit P50(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_002795.2|ensembl:ENSG00000165916(gene)|ensembl:ENST00000298852(transcript)|ensembl:ENST00000619920(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0043921"(modulation by host of viral transcription)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035254|interpro:IPR041569|mint:P17980|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|go:"GO:0036402"(proteasome-activating activity)|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-1236978|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-27555N|uniprotkb:P17980(identity)|entrezgene/locuslink:5702(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:CejeauChmqeXNwBYF2cPz7mgMuw9606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:P13674 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-1237386|uniprotkb:Q15082|uniprotkb:Q15083|uniprotkb:Q5VSQ5|uniprotkb:C9JL12|ensembl:ENSP00000307318|ensembl:ENSP00000378353 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:p4ha1_human(display_long)|uniprotkb:P4HA1(gene name)|psi-mi:P4HA1(display_short)|uniprotkb:P4HA(gene name synonym)|uniprotkb:Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_000908.2|refseq:NP_001017962.1|refseq:NP_001136067.1|refseq:NP_001136068.1|dip:DIP-38180N|ensembl:ENSG00000122884(gene)|ensembl:ENST00000307116(transcript)|ensembl:ENST00000394890(transcript)|go:"GO:0004656"(procollagen-proline 4-dioxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0016222"(procollagen-proline 4-dioxygenase complex)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013547(Prolyl 4-hydroxylase alpha-subunit, N-terminal)|interpro:IPR019734|mint:P13674|rcsb pdb:1TJC|rcsb pdb:2V5F|rcsb pdb:2YQ8|rcsb pdb:4BT8|rcsb pdb:4BT9|rcsb pdb:4BTA|rcsb pdb:4BTB|reactome:R-HSA-1650814|go:"GO:0043231"(intracellular membrane-bounded organelle)|uniprotkb:P13674(identity)|entrezgene/locuslink:5033(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:Yo9hgWVJ5iUGITVWKfvjhTNX1lk9606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:Q9H1A4 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-395918|uniprotkb:Q2M3H8|uniprotkb:Q9BSE6|uniprotkb:Q9H8D0|ensembl:ENSP00000339109 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:apc1_human(display_long)|uniprotkb:ANAPC1(gene name)|psi-mi:ANAPC1(display_short)|uniprotkb:TSG24(gene name synonym)|uniprotkb:Cyclosome subunit 1(gene name synonym)|uniprotkb:Testis-specific gene 24 protein(gene name synonym)|uniprotkb:Mitotic checkpoint regulator(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_073153.1|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENSG00000153107(gene)|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|ensembl:ENST00000341068(transcript)|go:"GO:0005654"(nucleoplasm)|rcsb pdb:5L9U|go:"GO:0005680"(anaphase-promoting complex)|rcsb pdb:5LCW|go:"GO:0005829"(cytosol)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|rcsb pdb:5LGG|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|interpro:IPR011989(Armadillo-like helical)|interpro:IPR024990|interpro:IPR041221|mint:Q9H1A4|dip:DIP-32940N|uniprotkb:Q9H1A4(identity)|entrezgene/locuslink:64682(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:GCcoaN+24WplwiaqcHwHsjyWn789606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:P28066 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-355475|uniprotkb:B4E2V4|uniprotkb:Q6IBF7|uniprotkb:Q3T1C1|uniprotkb:B2R8F6|ensembl:ENSP00000271308 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:psa5_human(display_long)|uniprotkb:PSMA5(gene name)|psi-mi:PSMA5(display_short)|uniprotkb:Proteasome zeta chain(gene name synonym)|uniprotkb:Macropain zeta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex zeta chain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_001186701.1|refseq:NP_001186702.1|refseq:NP_001186703.1|refseq:NP_002781.2|ensembl:ENSG00000143106(gene)|ensembl:ENST00000271308(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR033812|mint:P28066|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEY|rcsb pdb:5LEX|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-29368N|uniprotkb:P28066(identity)|entrezgene/locuslink:5686(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:bfMG3npzVetUH1tahr2MAI4R+3g9606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:P51665 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-357659|uniprotkb:Q6PKI2|uniprotkb:Q96E97|ensembl:ENSP00000219313|uniprotkb:D3DWS9 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:psmd7_human(display_long)|uniprotkb:PSMD7(gene name)|psi-mi:PSMD7(display_short)|uniprotkb:MOV34L(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN8(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S12(gene name synonym)|uniprotkb:Proteasome subunit p40(gene name synonym)|uniprotkb:Mov34 protein homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_002802.2|rcsb pdb:5T0J|ensembl:ENSG00000103035(gene)|ensembl:ENST00000219313(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0016020"(membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070122"(isopeptidase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR033858|interpro:IPR037518|mint:P51665|rcsb pdb:2O95|rcsb pdb:2O96|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-180534|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-195253|reactome:R-HSA-5676590|reactome:R-HSA-202424|reactome:R-HSA-5678895|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-2871837|reactome:R-HSA-5689880|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-6798695|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-68827|reactome:R-HSA-4641258|reactome:R-HSA-68949|reactome:R-HSA-5358346|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-27572N|uniprotkb:P51665(identity)|entrezgene/locuslink:5713(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:HJaBTx4pIiSDIArqueuNRvhzVvU9606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:P51570 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-2269932|uniprotkb:B2RC07|intact:EBI-6190170|uniprotkb:B4E1G6|ensembl:ENSP00000225614|ensembl:ENSP00000465930 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:galk1_human(display_long)|uniprotkb:GALK1(gene name)|psi-mi:GALK1(display_short)|uniprotkb:GALK(gene name synonym)|uniprotkb:Galactose kinase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) go:"GO:0019388"(galactose catabolic process)|go:"GO:0019402"(galactitol metabolic process)|go:"GO:0061623"(glycolytic process from galactose)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000705(Galactokinase)|interpro:IPR006203(GHMP kinase, ATP-binding, conserved site)|interpro:IPR006204(GHMP kinase)|interpro:IPR006206(Mevalonate and galactokinase)|interpro:IPR013750(GHMP kinase, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR019539|interpro:IPR019741|interpro:IPR020568|interpro:IPR036554|mint:P51570|ensembl:ENSG00000108479(gene)|ensembl:ENST00000225614(transcript)|ensembl:ENST00000588479(transcript)|go:"GO:0004335"(galactokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005534"(galactose binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0016020"(membrane)|rcsb pdb:1WUU|rcsb pdb:1YH7|rcsb pdb:6GR2|rcsb pdb:6Q3W|rcsb pdb:6Q3X|rcsb pdb:6Q8Z|rcsb pdb:6Q90|rcsb pdb:6Q91|rcsb pdb:6QJE|rcsb pdb:6ZFH|rcsb pdb:6ZGV|rcsb pdb:6ZGW|rcsb pdb:6ZGX|rcsb pdb:6ZGY|rcsb pdb:6ZGZ|reactome:R-HSA-5609976|reactome:R-HSA-70370|uniprotkb:P51570(identity)|entrezgene/locuslink:2584(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:TtFcTQq+nspsst+xInA/huo/ZbU9606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:P00367 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-356544|uniprotkb:Q5TBU3|ensembl:ENSP00000277865|uniprotkb:B3KV55|uniprotkb:B4DGN5 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:dhe3_human(display_long)|uniprotkb:GLUD1(gene name)|psi-mi:GLUD1(display_short)|uniprotkb:GLUD(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) ensembl:ENSG00000148672(gene)|ensembl:ENST00000277865(transcript)|go:"GO:0004352"("glutamate dehydrogenase (NAD+) activity")|go:"GO:0004353"("glutamate dehydrogenase [NAD(P)+] activity")|go:"GO:0004354"("glutamate dehydrogenase (NADP+) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0042802"(identical protein binding)|refseq:NP_005262.1|refseq:NP_001305829.1|refseq:NP_001305830.1|refseq:NP_001305831.1|refseq:NP_001305833.1|refseq:NP_001305834.1|refseq:NP_001305835.1|go:"GO:0043531"(ADP binding)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070728"(leucine binding)|go:"GO:0072350"(tricarboxylic acid metabolic process)|interpro:IPR006095(Glutamate/phenylalanine/leucine/valine dehydrogenase)|interpro:IPR006096(Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal)|interpro:IPR006097(Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation region)|interpro:IPR033524|interpro:IPR033922|interpro:IPR036291|mint:P00367|rcsb pdb:1L1F|rcsb pdb:1NR1|rcsb pdb:6DQG|reactome:R-HSA-2151201|reactome:R-HSA-8964539|uniprotkb:P00367(identity)|entrezgene/locuslink:2746(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:rWYi7otiOLlUvfEl7Vy6ELkY+BM9606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:P43307 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-714168|uniprotkb:A8K685|uniprotkb:Q9TNQ8|uniprotkb:Q53GX2|uniprotkb:Q53H19|uniprotkb:Q5TAM3|uniprotkb:Q6IB43|uniprotkb:Q8NBH9|uniprotkb:Q96IA2|uniprotkb:Q9UN49|ensembl:ENSP00000244763 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:ssra_human(display_long)|uniprotkb:Signal sequence receptor subunit alpha(gene name synonym)|uniprotkb:SSR1(gene name)|psi-mi:SSR1(display_short)|uniprotkb:TRAPA(gene name synonym)|uniprotkb:PSEC0262(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_003135.2|ensembl:ENSG00000124783(gene)|ensembl:ENST00000244763(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016021"(integral component of membrane)|interpro:IPR005595("Translocon-associated protein (TRAP), alpha subunit")|mint:P43307|reactome:R-HSA-1799339|reactome:R-HSA-381038|refseq:NP_001278937.1|uniprotkb:P43307(identity)|entrezgene/locuslink:6745(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:OhI1z1wbH8LEZaiv+OLChzMvT+A9606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:O00567 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-396034|uniprotkb:Q2M3T6|uniprotkb:Q9NQ05|ensembl:ENSP00000370589 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:nop56_human(display_long)|uniprotkb:NOP56(gene name)|psi-mi:NOP56(display_short)|uniprotkb:NOL5A(gene name synonym)|uniprotkb:Nucleolar protein 5A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_006383.2|ensembl:ENSG00000101361(gene)|ensembl:ENST00000329276(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070761"(pre-snoRNP complex)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|mint:O00567|reactome:R-HSA-390471|reactome:R-HSA-6790901|reactome:R-HSA-6791226|uniprotkb:O00567(identity)|entrezgene/locuslink:10528(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:nXIsxj5Spl+kflK0yGJFykVylmA9606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:Q5SY16 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-1055462|uniprotkb:Q4VBY3|uniprotkb:Q6P472|uniprotkb:Q7L4D6|uniprotkb:Q96EE0|uniprotkb:Q9H5L4|uniprotkb:Q2NL84|ensembl:ENSP00000366934 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:nol9_human(display_long)|uniprotkb:NOL9(gene name)|psi-mi:NOL9(display_short)|uniprotkb:Nucleolar protein 9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_078930.3|refseq:XP_011540449.1|ensembl:ENST00000377705(transcript)|go:"GO:0000448"("cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051731"(polynucleotide 5'-hydroxyl-kinase activity)|interpro:IPR027417|interpro:IPR032319|mint:Q5SY16|reactome:R-HSA-6791226|ensembl:ENSG00000162408(gene)|refseq:XP_016857827.1|refseq:XP_016857828.1|uniprotkb:Q5SY16(identity)|entrezgene/locuslink:79707(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:IWGhuh/G+MlTxlSXEcIml8tvK7Y9606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:Q9BQE3 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1|uniprotkb:Q9BQE3(identity)|entrezgene/locuslink:84790(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:P16615 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-358933|uniprotkb:P16614|uniprotkb:A6NDN7|uniprotkb:B4DF05|uniprotkb:Q86VJ2|ensembl:ENSP00000440045 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:at2a2_human(display_long)|uniprotkb:ATP2A2(gene name)|psi-mi:ATP2A2(display_short)|uniprotkb:ATP2B(gene name synonym)|uniprotkb:Calcium pump 2(gene name synonym)|uniprotkb:Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform(gene name synonym)|uniprotkb:"Endoplasmic reticulum class 1/2 Ca(2+) ATPase"(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_001672.1|refseq:NP_733765.1|refseq:XP_011536704.1|ensembl:ENSG00000174437(gene)|ensembl:ENST00000539276(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006984"(ER-nucleus signaling pathway)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008544"(epidermis development)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014801"(longitudinal sarcoplasmic reticulum)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016020"(membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019899"(enzyme binding)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031775"(lutropin-choriogonadotropic hormone receptor binding)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032470"(positive regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0061831"(apical ectoplasmic specialization)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086039"(P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential)|go:"GO:0090534"(calcium ion-transporting ATPase complex)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:0120025"(plasma membrane bounded cell projection)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1903233"(regulation of calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:1903515"(calcium ion transport from cytosol to endoplasmic reticulum)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1990036"(calcium ion import into sarcoplasmic reticulum)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005782(Calcium ATPase)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P16615|rcsb pdb:5ZTF|rcsb pdb:6JJU|rcsb pdb:6LLE|rcsb pdb:6LLY|rcsb pdb:6LN5|rcsb pdb:6LN6|rcsb pdb:6LN7|rcsb pdb:6LN8|rcsb pdb:6LN9|rcsb pdb:7BT2|reactome:R-HSA-1912420|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|go:"GO:0000045"(autophagosome assembly)|refseq:XP_005253945.1|dip:DIP-33868N|uniprotkb:P16615(identity)|entrezgene/locuslink:488(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:QlJZW2fprLYahKUrHDOVs28kA2w9606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:Q9NVI7 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-352007|ensembl:ENSP00000368030|uniprotkb:Q5SV23|uniprotkb:Q8N275|uniprotkb:Q96A50|uniprotkb:B3KPB3|uniprotkb:D2K8Q1|uniprotkb:G3V1I6 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:atd3a_human(display_long)|uniprotkb:ATAD3A(gene name)|psi-mi:ATAD3A(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_001164006.1|refseq:NP_001164007.1|refseq:NP_060658.3|ensembl:ENSG00000197785(gene)|ensembl:ENST00000378755(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR021911|interpro:IPR027417|interpro:IPR039188|mint:Q9NVI7|dip:DIP-33194N|uniprotkb:Q9NVI7(identity)|entrezgene/locuslink:55210(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:IZKJEVLLS/DFINgBgO5frizN1P49606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:P25788 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-348380|ensembl:ENSP00000216455|uniprotkb:Q86U83|uniprotkb:Q8N1D8|uniprotkb:Q9BS70|uniprotkb:B2RCK6 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:psa3_human(display_long)|uniprotkb:PSMA3(gene name)|psi-mi:PSMA3(display_short)|uniprotkb:PSC8(gene name synonym)|uniprotkb:Proteasome component C8(gene name synonym)|uniprotkb:Macropain subunit C8(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C8(gene name synonym)|uniprotkb:HC8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_002779.1|refseq:NP_687033.1|ensembl:ENSG00000100567(gene)|ensembl:ENST00000216455(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0045202"(synapse)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR037555|mint:P25788|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|rcsb pdb:5DSV|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|rcsb pdb:7E55|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|rcsb pdb:5T0H|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-174084|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-174113|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|dip:DIP-29366N|uniprotkb:P25788(identity)|entrezgene/locuslink:5684(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:9Er/PY50/GVoCr5yAPXlkfxtP0k9606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:P62333 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-357669|uniprotkb:Q92524|uniprotkb:P49719|uniprotkb:Q6IBU3|uniprotkb:B2R975|ensembl:ENSP00000401802 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:prs10_human(display_long)|uniprotkb:PSMC6(gene name)|psi-mi:PSMC6(display_short)|uniprotkb:SUG2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 6(gene name synonym)|uniprotkb:Proteasome subunit p42(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_002797.3|ensembl:ENST00000445930(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000100519(gene)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR032501|interpro:IPR035263|interpro:IPR041569|mint:P62333|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-75815|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-174184|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|dip:DIP-38150N|uniprotkb:P62333(identity)|entrezgene/locuslink:5706(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:QE8jzSEp1bpzhOi/oAAnV18QK249606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:O43242 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-357622|uniprotkb:Q96EI2|uniprotkb:Q9BQA4|ensembl:ENSP00000264639|uniprotkb:B4DT72|uniprotkb:B3KMW9 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:psmd3_human(display_long)|uniprotkb:PSMD3(gene name)|psi-mi:PSMD3(display_short)|uniprotkb:Proteasome subunit p58(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S3(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) ensembl:ENSG00000108344(gene)|ensembl:ENST00000264639(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013586(26S proteasome regulatory subunit, C-terminal)|interpro:IPR035267|interpro:IPR036390|mint:O43242|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|reactome:R-HSA-174113|reactome:R-HSA-174154|rcsb pdb:5VHH|rcsb pdb:5VHI|reactome:R-HSA-174178|rcsb pdb:5VHS|reactome:R-HSA-174184|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|reactome:R-HSA-180534|rcsb pdb:6MSJ|reactome:R-HSA-180585|reactome:R-HSA-187577|rcsb pdb:6MSK|reactome:R-HSA-195253|reactome:R-HSA-202424|rcsb pdb:6WJD|reactome:R-HSA-211733|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-174084|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5607761|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-8854050|refseq:NP_002800.2|dip:DIP-27571N|uniprotkb:O43242(identity)|entrezgene/locuslink:5709(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:C6CStW89nIAA3mzubyv5wfBwPHk9606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:Q16543 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-295634|uniprotkb:Q53YA2|ensembl:ENSP00000222005 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:cdc37_human(display_long)|uniprotkb:CDC37(gene name)|psi-mi:CDC37(display_short)|uniprotkb:Hsp90 chaperone protein kinase-targeting subunit(gene name synonym)|uniprotkb:p50Cdc37(gene name synonym)|uniprotkb:CDC37A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_008996.1|dip:DIP-27560N|ensembl:ENSG00000105401(gene)|ensembl:ENST00000222005(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006605"(protein targeting)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0101031"(chaperone complex)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|interpro:IPR004918(Cdc37)|interpro:IPR013855(Cdc37, N-terminal)|interpro:IPR013873(Cdc37, C-terminal)|interpro:IPR013874(Cdc37, Hsp90 binding)|interpro:IPR038189|mint:Q16543|rcsb pdb:1US7|rcsb pdb:2K5B|rcsb pdb:2N5X|rcsb pdb:2NCA|rcsb pdb:2W0G|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5HPE|reactome:R-HSA-1227986|reactome:R-HSA-1236382|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-9013418|reactome:R-HSA-9634285|reactome:R-HSA-9652282|reactome:R-HSA-9664565|reactome:R-HSA-9665233|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|uniprotkb:Q16543(identity)|entrezgene/locuslink:11140(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:iajhitd2iEmd17KfpU/nMaKc4049606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:P28074 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-357828|uniprotkb:Q16242|uniprotkb:Q6PEW2|intact:EBI-1237472|uniprotkb:Q7Z3B5|uniprotkb:Q9TNN9|uniprotkb:B2R4N9|uniprotkb:D3DS43|uniprotkb:B4DUM9|uniprotkb:Q86T01|uniprotkb:E9PAV2|ensembl:ENSP00000355325 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:psb5_human(display_long)|uniprotkb:PSMB5(gene name)|psi-mi:PSMB5(display_short)|uniprotkb:LMPX(gene name synonym)|uniprotkb:Proteasome epsilon chain(gene name synonym)|uniprotkb:Macropain epsilon chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex epsilon chain(gene name synonym)|uniprotkb:Proteasome subunit X(gene name synonym)|uniprotkb:Proteasome chain 6(gene name synonym)|uniprotkb:Proteasome subunit MB1(gene name synonym)|uniprotkb:MB1(gene name synonym)|uniprotkb:X(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_001124197.1|refseq:NP_001138404.1|refseq:NP_002788.1|dip:DIP-27540N|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5610785|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|ensembl:ENSG00000100804(gene)|ensembl:ENST00000361611(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006508"(proteolysis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008233"(peptidase activity)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|mint:P28074|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|uniprotkb:P28074(identity)|entrezgene/locuslink:5693(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:73T59wniLri/465F3BhBvwL1/LM9606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:O00231 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-357816|uniprotkb:O00495|uniprotkb:A8K3I7|uniprotkb:E1P663|uniprotkb:Q53FT5|ensembl:ENSP00000261712|ensembl:ENSP00000393185|ensembl:ENSP00000497128 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:psd11_human(display_long)|uniprotkb:PSMD11(gene name)|psi-mi:PSMD11(display_short)|uniprotkb:26S proteasome regulatory subunit S9(gene name synonym)|uniprotkb:26S proteasome regulatory subunit p44.5(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_002806.2|refseq:NP_001257411.1|ensembl:ENSG00000108671(gene)|ensembl:ENST00000261712(transcript)|ensembl:ENST00000457654(transcript)|ensembl:ENST00000649012(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048863"(stem cell differentiation)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR035295|interpro:IPR036390|interpro:IPR040773|interpro:IPR040780|mint:O00231|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5M32|rcsb pdb:5LN3|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|uniprotkb:O00231(identity)|entrezgene/locuslink:5717(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:BgQKXK7gMMihacRCI+g/pBnRN309606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:P33993 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-355924|uniprotkb:Q15076|uniprotkb:Q96D34|uniprotkb:Q96GL1|uniprotkb:A4D2A1|uniprotkb:A4D2A2|uniprotkb:E9PGN9|ensembl:ENSP00000307288 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:mcm7_human(display_long)|uniprotkb:MCM7(gene name)|psi-mi:MCM7(display_short)|uniprotkb:CDC47(gene name synonym)|uniprotkb:MCM2(gene name synonym)|uniprotkb:CDC47 homolog(gene name synonym)|uniprotkb:P1.1-MCM3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_001265524.1|refseq:NP_005907.3|refseq:NP_877577.1|ensembl:ENSG00000166508(gene)|ensembl:ENST00000303887(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0016020"(membrane)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008283"(cell population proliferation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P33993|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|dip:DIP-27580N|uniprotkb:P33993(identity)|entrezgene/locuslink:4176(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:hrpCntkzdVgewNA+/iPS6b50dGY9606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:Q9Y2X3 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-395469|uniprotkb:Q53SA4|uniprotkb:Q6PK08|uniprotkb:Q9P036|uniprotkb:Q9UFN3|ensembl:ENSP00000264279 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:nop58_human(display_long)|uniprotkb:NOP58(gene name)|psi-mi:NOP58(display_short)|uniprotkb:NOL5(gene name synonym)|uniprotkb:Nucleolar protein 5(gene name synonym)|uniprotkb:NOP5(gene name synonym)|uniprotkb:HSPC120(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_057018.1|ensembl:ENSG00000055044(gene)|ensembl:ENST00000264279(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0015030"(Cajal body)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|go:"GO:0016020"(membrane)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|mint:Q9Y2X3|reactome:R-HSA-4570464|reactome:R-HSA-6790901|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|reactome:R-HSA-6791226|go:"GO:0032040"(small-subunit processome)|go:"GO:0048254"(snoRNA localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0070761"(pre-snoRNP complex)|dip:DIP-32926N|uniprotkb:Q9Y2X3(identity)|entrezgene/locuslink:51602(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:L7mE30ZNpQbKsQElFrrDMBQwG+w9606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:P51571 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-1054539|uniprotkb:Q53XY1|uniprotkb:A8K378|ensembl:ENSP00000317331|ensembl:ENSP00000359103|ensembl:ENSP00000359104 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:ssrd_human(display_long)|uniprotkb:Signal sequence receptor subunit delta(gene name synonym)|uniprotkb:SSR4(gene name)|psi-mi:SSR4(display_short)|uniprotkb:TRAPD(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_001191455.1|refseq:NP_006271.1|refseq:XP_011529488.1|refseq:XP_011529489.1|ensembl:ENSG00000180879(gene)|ensembl:ENST00000320857(transcript)|ensembl:ENST00000370086(transcript)|ensembl:ENST00000370087(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008855(Translocon-associated)|mint:P51571|reactome:R-HSA-1799339|uniprotkb:P51571(identity)|entrezgene/locuslink:6748(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:2SNgZQH/jwi61UcuHUf7RYKZH589606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:Q9P2R7 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-2269898|uniprotkb:O95194|uniprotkb:Q5T9Q4|uniprotkb:Q5T9Q6|uniprotkb:Q9NV21|uniprotkb:Q9NVP7|uniprotkb:B2RDE7|ensembl:ENSP00000494360|ensembl:ENSP00000494987 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:sucb1_human(display_long)|uniprotkb:SUCLA2(gene name)|psi-mi:SUCLA2(display_short)|uniprotkb:ATP-specific succinyl-CoA synthetase subunit beta(gene name synonym)|uniprotkb:Succinyl-CoA synthetase beta-A chain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_003841.1|ensembl:ENSG00000136143(gene)|ensembl:ENST00000643584(transcript)|ensembl:ENST00000646932(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004775"("succinate-CoA ligase (ADP-forming) activity")|go:"GO:0004776"("succinate-CoA ligase (GDP-forming) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0006781"(succinyl-CoA pathway)|go:"GO:0042709"(succinate-CoA ligase complex)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005809(Succinyl-CoA synthetase, beta subunit)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013650(ATP-grasp fold, succinyl-CoA synthetase-type)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR017866|interpro:IPR034723|mint:Q9P2R7|rcsb pdb:6G4Q|reactome:R-HSA-71403|uniprotkb:Q9P2R7(identity)|entrezgene/locuslink:8803(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:I/FQp3c8ckxpxoyftKge2B5lDmI9606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:Q3ZCQ8 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-355175|uniprotkb:Q6QA00|uniprotkb:Q96FJ5|uniprotkb:Q96GY2|uniprotkb:Q9H370|intact:EBI-2554785|uniprotkb:Q330K1|ensembl:ENSP00000475531 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:tim50_human(display_long)|uniprotkb:TIMM50(gene name)|psi-mi:TIMM50(display_short)|uniprotkb:TIM50(gene name synonym)|uniprotkb:PRO1512(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_001001563.1|ensembl:ENSG00000105197(gene)|ensembl:ENST00000607714(transcript)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003723"(RNA binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005134"(interleukin-2 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007006"(mitochondrial membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR004274(NLI interacting factor)|interpro:IPR023214|interpro:IPR027111|interpro:IPR036412|mint:Q3ZCQ8|reactome:R-HSA-1268020|refseq:NP_001316488.1|dip:DIP-34058N|uniprotkb:Q3ZCQ8(identity)|entrezgene/locuslink:92609(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:fOPV33h12YhAq9jj0bVno01Q+6g9606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:P49721 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-359335|uniprotkb:P31145|uniprotkb:Q9BWZ9|uniprotkb:D3DPS0|ensembl:ENSP00000362334 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:psb2_human(display_long)|uniprotkb:PSMB2(gene name)|psi-mi:PSMB2(display_short)|uniprotkb:Multicatalytic endopeptidase complex subunit C7-I(gene name synonym)|uniprotkb:Proteasome component C7-I(gene name synonym)|uniprotkb:Macropain subunit C7-I(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_002785.1|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5GJR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-5689603|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000126067(gene)|ensembl:ENST00000373237(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035206|mint:P49721|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|dip:DIP-33848N|uniprotkb:P49721(identity)|entrezgene/locuslink:5690(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:PvXrk6RLayQ1zqmavn1cONfA9/A9606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:Q9BVA1 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-355665|uniprotkb:A8K068|ensembl:ENSP00000259818 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:tbb2b_human(display_long)|uniprotkb:TUBB2B(gene name)|psi-mi:TUBB2B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_821080.1|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:1902669"(positive regulation of axon guidance)|go:"GO:1990403"(embryonic brain development)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BVA1|rcsb pdb:6E7C|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|ensembl:ENST00000259818(transcript)|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-5663220|ensembl:ENSG00000137285(gene)|uniprotkb:Q9BVA1(identity)|entrezgene/locuslink:347733(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:sluQMryNuOvp6xlV558+agiRwvE9606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:P28072 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-359288|uniprotkb:Q96J55|ensembl:ENSP00000270586 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:psb6_human(display_long)|uniprotkb:PSMB6(gene name)|psi-mi:PSMB6(display_short)|uniprotkb:LMPY(gene name synonym)|uniprotkb:Proteasome delta chain(gene name synonym)|uniprotkb:Macropain delta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex delta chain(gene name synonym)|uniprotkb:Proteasome subunit Y(gene name synonym)|uniprotkb:Y(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_002789.1|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035140|mint:P28072|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|go:"GO:0005737"(cytoplasm)|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000142507(gene)|ensembl:ENST00000270586(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-33847N|uniprotkb:P28072(identity)|entrezgene/locuslink:5694(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:4LRxYA6/tM2hsc96iP29c5J7ew49606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:Q9Y2X9 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-396200|uniprotkb:Q9NY92|uniprotkb:A6NF48|uniprotkb:B3KMX2|uniprotkb:Q5RKW5|intact:EBI-11018373|ensembl:ENSP00000294740|ensembl:ENSP00000356322 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:zn281_human(display_long)|uniprotkb:ZNF281(gene name)|psi-mi:ZNF281(display_short)|uniprotkb:GZP1(gene name synonym)|uniprotkb:ZBP99(gene name synonym)|uniprotkb:Zinc finger DNA-binding protein 99(gene name synonym)|uniprotkb:Transcription factor ZBP-99(gene name synonym)|uniprotkb:GC-box-binding zinc finger protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_036614.1|refseq:NP_001268222.1|refseq:NP_001268223.1|refseq:XP_016856376.1|refseq:XP_016856377.1|ensembl:ENSG00000162702(gene)|ensembl:ENST00000294740(transcript)|ensembl:ENST00000367353(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9Y2X9|uniprotkb:Q9Y2X9(identity)|entrezgene/locuslink:23528(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:bjmz9ne6FkC0kbJUv13u8IoDYHM9606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:P43686 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-743997|uniprotkb:Q96FV5|uniprotkb:Q9UBM3|uniprotkb:Q9UEX3|ensembl:ENSP00000157812|ensembl:ENSP00000487367 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:prs6b_human(display_long)|uniprotkb:Proteasome 26S subunit ATPase 4(gene name synonym)|uniprotkb:MB67-interacting protein(gene name synonym)|uniprotkb:PSMC4(gene name)|psi-mi:PSMC4(display_short)|uniprotkb:TBP7(gene name synonym)|uniprotkb:MIP224(gene name synonym)|uniprotkb:Tat-binding protein 7(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_006494.1|refseq:NP_694546.1|dip:DIP-29274N|ensembl:ENSG00000013275(gene)|ensembl:ENSG00000281221(gene)|ensembl:ENST00000157812(transcript)|ensembl:ENST00000629691(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045202"(synapse)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035256|interpro:IPR041569|mint:P43686|rcsb pdb:2DVW|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-69601|uniprotkb:P43686(identity)|entrezgene/locuslink:5704(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:ZwHUFX8vJa8IPZi000dHiFtUtlM9606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:Q15008 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-359701|uniprotkb:E9PHI9|uniprotkb:A8K2E0|ensembl:ENSP00000295901|uniprotkb:Q6UV22 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:psmd6_human(display_long)|uniprotkb:PSMD6(gene name)|psi-mi:PSMD6(display_short)|uniprotkb:KIAA0107(gene name synonym)|uniprotkb:PFAAP4(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S10(gene name synonym)|uniprotkb:p42A(gene name synonym)|uniprotkb:Proteasome regulatory particle subunit p44S10(gene name synonym)|uniprotkb:Phosphonoformate immuno-associated protein 4(gene name synonym)|uniprotkb:Breast cancer-associated protein SGA-113M(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_055629.1|ensembl:ENSG00000163636(gene)|ensembl:ENST00000295901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019585|interpro:IPR035268|interpro:IPR036390|mint:Q15008|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|reactome:R-HSA-5358346|reactome:R-HSA-1236978|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-1236974|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-69601|reactome:R-HSA-69481|refseq:NP_001258708.1|refseq:NP_001258709.1|refseq:NP_001258710.1|dip:DIP-27590N|uniprotkb:Q15008(identity)|entrezgene/locuslink:9861(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:ULOM02v6J56vZLlAGn7wN3N6Efw9606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:Q14498 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-395290|uniprotkb:A5D8W2|uniprotkb:B0BLV3|uniprotkb:Q14499|uniprotkb:A2RRD3|uniprotkb:E1P5S0|uniprotkb:E1P5S1|ensembl:ENSP00000253363 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:rbm39_human(display_long)|uniprotkb:HCC1(gene name synonym)|uniprotkb:RBM39(gene name)|psi-mi:RBM39(display_short)|uniprotkb:RNA-binding motif protein 39(gene name synonym)|uniprotkb:RNA-binding region-containing protein 2(gene name synonym)|uniprotkb:Hepatocellular carcinoma protein 1(gene name synonym)|uniprotkb:Splicing factor HCC1(gene name synonym)|uniprotkb:RNPC2(gene name synonym)|uniprotkb:CAPER alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_001229528.1|refseq:NP_001229529.1|refseq:NP_004893.1|refseq:NP_909122.1|ensembl:ENSG00000131051(gene)|ensembl:ENST00000253363(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016607"(nuclear speck)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0050733"(RS domain binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006509(Splicing factor, CC1-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029123|interpro:IPR035979|mint:Q14498|rcsb pdb:2JRS|rcsb pdb:2MHN|rcsb pdb:4OO6|rcsb pdb:4OZ0|rcsb pdb:4OZ1|rcsb pdb:4YUD|rcsb pdb:6PAI|rcsb pdb:6Q0R|rcsb pdb:6Q0V|rcsb pdb:6Q0W|rcsb pdb:6SJ7|rcsb pdb:6UD7|rcsb pdb:6UE5|dip:DIP-32928N|uniprotkb:Q14498(identity)|entrezgene/locuslink:9584(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:/e7HNZt0CtcDKTwF8BqSwNpyufc9606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:P35998 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-359710|uniprotkb:B7Z5E2|uniprotkb:A4D0Q1|uniprotkb:Q3LIA5|uniprotkb:Q9UDI3|ensembl:ENSP00000292644|ensembl:ENSP00000391211|ensembl:ENSP00000502939|ensembl:ENSP00000503179|ensembl:ENSP00000504608 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:prs7_human(display_long)|uniprotkb:PSMC2(gene name)|psi-mi:PSMC2(display_short)|uniprotkb:MSS1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 2(gene name synonym)|uniprotkb:Protein MSS1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_001191382.1|refseq:NP_002794.1|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR035245|interpro:IPR041569|mint:P35998|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|interpro:IPR003960(AAA ATPase, conserved site)|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|ensembl:ENSG00000161057(gene)|ensembl:ENST00000292644(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|ensembl:ENST00000435765(transcript)|ensembl:ENST00000678493(transcript)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|ensembl:ENST00000679205(transcript)|ensembl:ENST00000679341(transcript)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0043197"(dendritic spine)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5VHQ|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5610780|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|dip:DIP-27554N|uniprotkb:P35998(identity)|entrezgene/locuslink:5701(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:ahQfjPKywP5DWNq3FB5XCjuqkJ09606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:Q9BUF5 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-356735|uniprotkb:Q9HA42|ensembl:ENSP00000318697|uniprotkb:B3KM76 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:tbb6_human(display_long)|uniprotkb:TUBB6(gene name)|psi-mi:TUBB6(display_short)|uniprotkb:Tubulin beta class V(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) ensembl:ENSG00000176014(gene)|ensembl:ENST00000317702(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|refseq:NP_115914.1|interpro:IPR036525|interpro:IPR037103|mint:Q9BUF5|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_001290453.1|refseq:NP_001290454.1|refseq:NP_001290455.1|refseq:NP_001290456.1|refseq:NP_001290457.1|refseq:NP_001290458.1|refseq:NP_001290459.1|uniprotkb:Q9BUF5(identity)|entrezgene/locuslink:84617(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:/IC9o8wSAOu+lNgq44Qqu5hEof49606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:P49720 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-603340|uniprotkb:P31147|uniprotkb:Q0P6J7|uniprotkb:Q96E27|ensembl:ENSP00000483688|ensembl:ENSP00000483956 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:psb3_human(display_long)|uniprotkb:PSMB3(gene name)|psi-mi:PSMB3(display_short)|uniprotkb:Proteasome theta chain(gene name synonym)|uniprotkb:Proteasome chain 13(gene name synonym)|uniprotkb:Proteasome component C10-II(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833199|imex:IM-21659-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding)|uniprotkb:Q9Y468(identity)|ddbj/embl/genbank:BC039820(identity)|entrezgene/locuslink:26013(identity) refseq:NP_002786.2|dip:DIP-33846N|ensembl:ENSG00000275903(gene)|ensembl:ENSG00000277791(gene)|ensembl:ENST00000619426(transcript)|ensembl:ENST00000619951(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR033811|mint:P49720|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|uniprotkb:P49720(identity)|entrezgene/locuslink:5691(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:H4UDdXV1BaXHp6mEPafNy+Iv8389606 intact-crc:548C985CC3AA7AC4|rigid:NnVpVLw8dXbxO4oNDXn7vmqlZhw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969R5 uniprotkb:Q99471 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 intact:EBI-357275|ensembl:ENSP00000334188|ensembl:ENSP00000447942|intact:EBI-1047551|uniprotkb:A8K9A8|uniprotkb:Q54AA8|uniprotkb:Q9C083|uniprotkb:Q9C084 psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:pfd5_human(display_long)|uniprotkb:c-Myc-binding protein Mm-1(gene name synonym)|uniprotkb:PFDN5(gene name)|psi-mi:PFDN5(display_short)|uniprotkb:MM1(gene name synonym)|uniprotkb:Myc modulator 1(gene name synonym)|uniprotkb:PFD5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833409|imex:IM-21659-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750|uniprotkb:Q969R5(identity)|entrezgene/locuslink:83746(identity)|ddbj/embl/genbank:BC017191(identity) ensembl:ENSG00000123349(gene)|ensembl:ENST00000334478(transcript)|ensembl:ENST00000551018(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR011599(Prefoldin alpha subunit)|mint:Q99471|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957|refseq:NP_002615.2|refseq:NP_665904.1|dip:DIP-28155N|uniprotkb:Q99471(identity)|entrezgene/locuslink:5204(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rogid:Cm4km207qcfDJYRUCIwUxMBT4tE9606 intact-crc:4E14595AB0781831|rigid:u7Tq4Bg9nRpH1HUHI6Sw/uARZrQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969R5 uniprotkb:P78371 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300 psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833409|imex:IM-21659-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750|uniprotkb:Q969R5(identity)|entrezgene/locuslink:83746(identity)|ddbj/embl/genbank:BC017191(identity) refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695|uniprotkb:P78371(identity)|entrezgene/locuslink:10576(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606 intact-crc:4E14595AB0781831|rigid:u7Tq4Bg9nRpH1HUHI6Sw/uARZrQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969R5 uniprotkb:P31151 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 intact:EBI-357520|uniprotkb:Q6FGE3|uniprotkb:Q5SY67|uniprotkb:Q9H1E2|ensembl:ENSP00000357711|ensembl:ENSP00000357712 psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:s10a7_human(display_long)|uniprotkb:S100A7(gene name)|psi-mi:S100A7(display_short)|uniprotkb:PSOR1(gene name synonym)|uniprotkb:S100A7C(gene name synonym)|uniprotkb:S100 calcium-binding protein A7(gene name synonym)|uniprotkb:Psoriasin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833409|imex:IM-21659-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750|uniprotkb:Q969R5(identity)|entrezgene/locuslink:83746(identity)|ddbj/embl/genbank:BC017191(identity) ensembl:ENSG00000143556(gene)|ensembl:ENST00000368722(transcript)|ensembl:ENST00000368723(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001525"(angiogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008544"(epidermis development)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045087"(innate immune response)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051238"(sequestering of metal ion)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071624"(positive regulation of granulocyte chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028477|interpro:IPR034325|mint:P31151|rcsb pdb:1PSR|rcsb pdb:2PSR|rcsb pdb:2WND|rcsb pdb:2WOR|rcsb pdb:2WOS|rcsb pdb:3PSR|rcsb pdb:4AQJ|reactome:R-HSA-6798695|reactome:R-HSA-6799990|refseq:NP_002954.2|uniprotkb:P31151(identity)|entrezgene/locuslink:6278(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rogid:/v8+XQ7rCMTYzq9k/KqjcSm/G0A9606 intact-crc:4E14595AB0781831|rigid:u7Tq4Bg9nRpH1HUHI6Sw/uARZrQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969R5 uniprotkb:P40227 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2 psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833409|imex:IM-21659-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750|uniprotkb:Q969R5(identity)|entrezgene/locuslink:83746(identity)|ddbj/embl/genbank:BC017191(identity) refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N|uniprotkb:P40227(identity)|entrezgene/locuslink:908(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606 intact-crc:4E14595AB0781831|rigid:u7Tq4Bg9nRpH1HUHI6Sw/uARZrQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969R5 uniprotkb:Q06587 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833409|imex:IM-21659-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750|uniprotkb:Q969R5(identity)|entrezgene/locuslink:83746(identity)|ddbj/embl/genbank:BC017191(identity) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 intact-crc:4E14595AB0781831|rigid:u7Tq4Bg9nRpH1HUHI6Sw/uARZrQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969R5 uniprotkb:Q14186 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833409|imex:IM-21659-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750|uniprotkb:Q969R5(identity)|entrezgene/locuslink:83746(identity)|ddbj/embl/genbank:BC017191(identity) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|entrezgene/locuslink:7027(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 intact-crc:4E14595AB0781831|rigid:u7Tq4Bg9nRpH1HUHI6Sw/uARZrQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969R5 uniprotkb:Q92769 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 intact:EBI-301821|uniprotkb:Q5SRI8|uniprotkb:Q5SZ86|uniprotkb:Q8NEH4|uniprotkb:B4DL58|ensembl:ENSP00000430432|uniprotkb:E1P561|uniprotkb:B3KRS5 psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:hdac2_human(display_long)|uniprotkb:HDAC2(gene name)|psi-mi:HDAC2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833409|imex:IM-21659-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750|uniprotkb:Q969R5(identity)|entrezgene/locuslink:83746(identity)|ddbj/embl/genbank:BC017191(identity) go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035094"(response to nicotine)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042220"(response to cocaine)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q92769|rcsb pdb:3MAX|rcsb pdb:4LXZ|rcsb pdb:4LY1|rcsb pdb:5IWG|rcsb pdb:5IX0|rcsb pdb:6G3O|rcsb pdb:6WBW|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000196591(gene)|ensembl:ENST00000519065(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|rcsb pdb:6WHN|rcsb pdb:6WHO|rcsb pdb:6WHQ|rcsb pdb:6WHZ|rcsb pdb:6WI3|rcsb pdb:6XDM|rcsb pdb:6XEB|rcsb pdb:6XEC|rcsb pdb:7KBG|rcsb pdb:7KBH|rcsb pdb:7LTG|rcsb pdb:7LTK|rcsb pdb:7LTL|reactome:R-HSA-193670|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9615017|reactome:R-HSA-9619665|reactome:R-HSA-9679191|reactome:R-HSA-983231|rcsb pdb:6WBZ|refseq:NP_001518.3|dip:DIP-24220N|refseq:XP_011534090.1|refseq:XP_016866288.1|uniprotkb:Q92769(identity)|entrezgene/locuslink:3066(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rogid:K4PpGz9E9/TrQZsgvrJuc+uYCn89606 intact-crc:4E14595AB0781831|rigid:u7Tq4Bg9nRpH1HUHI6Sw/uARZrQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969R5 uniprotkb:Q13547 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 intact:EBI-301834|uniprotkb:Q92534|ensembl:ENSP00000362649 psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:hdac1_human(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:RPD3L1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833409|imex:IM-21659-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750|uniprotkb:Q969R5(identity)|entrezgene/locuslink:83746(identity)|ddbj/embl/genbank:BC017191(identity) ensembl:ENSG00000116478(gene)|ensembl:ENST00000373548(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007492"(endoderm development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031000"(response to caffeine)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043044"|go:"GO:0019213"(deacetylase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900221"(regulation of amyloid-beta clearance)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q13547|rcsb pdb:1TYI|rcsb pdb:4BKX|rcsb pdb:5ICN|rcsb pdb:6Z2J|rcsb pdb:6Z2K|rcsb pdb:7AO8|rcsb pdb:7AO9|rcsb pdb:7AOA|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-193670|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-3769402|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-4641265|reactome:R-HSA-6804758|reactome:R-HSA-69205|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9022538|reactome:R-HSA-9022692|go:"GO:0017053"(transcription repressor complex)|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9615017|reactome:R-HSA-9679191|reactome:R-HSA-983231|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:NP_004955.2|dip:DIP-24184N|uniprotkb:Q13547(identity)|entrezgene/locuslink:3065(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rogid:RP+yIBWH55NgoPTY1nKXqeJL/xY9606 intact-crc:4E14595AB0781831|rigid:u7Tq4Bg9nRpH1HUHI6Sw/uARZrQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969R5 uniprotkb:P49368 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688 psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833409|imex:IM-21659-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750|uniprotkb:Q969R5(identity)|entrezgene/locuslink:83746(identity)|ddbj/embl/genbank:BC017191(identity) refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N|uniprotkb:P49368(identity)|entrezgene/locuslink:7203(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606 intact-crc:4E14595AB0781831|rigid:u7Tq4Bg9nRpH1HUHI6Sw/uARZrQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969R5 uniprotkb:Q99496 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833409|imex:IM-21659-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750|uniprotkb:Q969R5(identity)|entrezgene/locuslink:83746(identity)|ddbj/embl/genbank:BC017191(identity) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|entrezgene/locuslink:6045(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 intact-crc:4E14595AB0781831|rigid:u7Tq4Bg9nRpH1HUHI6Sw/uARZrQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969R5 uniprotkb:Q9H0A8 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 intact:EBI-1550064|uniprotkb:Q7L637|uniprotkb:Q9NX43|uniprotkb:B2RBN4|uniprotkb:H3BUL2|ensembl:ENSP00000267935|ensembl:ENSP00000433662 psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:comd4_human(display_long)|uniprotkb:COMMD4(gene name)|psi-mi:COMMD4(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833409|imex:IM-21659-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750|uniprotkb:Q969R5(identity)|entrezgene/locuslink:83746(identity)|ddbj/embl/genbank:BC017191(identity) refseq:NP_001271306.1|refseq:NP_060298.2|refseq:NP_001271307.1|ensembl:ENSG00000140365(gene)|ensembl:ENST00000267935(transcript)|ensembl:ENST00000480484(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR017920|interpro:IPR037356|reactome:R-HSA-8951664|uniprotkb:Q9H0A8(identity)|entrezgene/locuslink:54939(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rogid:v1pkDNc18f7sZM/89Gv0bho9GN89606 intact-crc:4E14595AB0781831|rigid:u7Tq4Bg9nRpH1HUHI6Sw/uARZrQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969R5 uniprotkb:P61964 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833409|imex:IM-21659-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750|uniprotkb:Q969R5(identity)|entrezgene/locuslink:83746(identity)|ddbj/embl/genbank:BC017191(identity) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|entrezgene/locuslink:11091(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 intact-crc:4E14595AB0781831|rigid:u7Tq4Bg9nRpH1HUHI6Sw/uARZrQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969R5 uniprotkb:Q9BYE7 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833409|imex:IM-21659-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750|uniprotkb:Q969R5(identity)|entrezgene/locuslink:83746(identity)|ddbj/embl/genbank:BC017191(identity) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 intact-crc:4E14595AB0781831|rigid:u7Tq4Bg9nRpH1HUHI6Sw/uARZrQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969R5 uniprotkb:Q13185 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833409|imex:IM-21659-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750|uniprotkb:Q969R5(identity)|entrezgene/locuslink:83746(identity)|ddbj/embl/genbank:BC017191(identity) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 intact-crc:4E14595AB0781831|rigid:u7Tq4Bg9nRpH1HUHI6Sw/uARZrQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969R5 uniprotkb:O75528 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 intact:EBI-473249|uniprotkb:Q9UFS2|intact:EBI-28973289|ensembl:ENSP00000307684|ensembl:ENSP00000393471|uniprotkb:Q6FI83 psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:tada3_human(display_long)|uniprotkb:ADA3 homolog(gene name synonym)|uniprotkb:STAF54(gene name synonym)|uniprotkb:TADA3(gene name)|psi-mi:TADA3(display_short)|uniprotkb:ADA3(gene name synonym)|uniprotkb:TADA3L(gene name synonym)|uniprotkb:Transcriptional adapter 3-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833409|imex:IM-21659-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750|uniprotkb:Q969R5(identity)|entrezgene/locuslink:83746(identity)|ddbj/embl/genbank:BC017191(identity) ensembl:ENSG00000171148(gene)|ensembl:ENST00000301964(transcript)|ensembl:ENST00000440161(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030914"|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR019340|mint:O75528|reactome:R-HSA-3214847|reactome:R-HSA-5689880|ensembl:ENSP00000307684|ensembl:ENST00000343450|ensembl:ENSP00000343649|ensembl:ENSP00000393471|refseq:NP_006345.1|refseq:NP_597814.1|refseq:NP_001265199.1|uniprotkb:O75528(identity)|entrezgene/locuslink:10474(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rogid:5NQkQiw+G/8uL2fjoMgW8+mTB8o9606 intact-crc:4E14595AB0781831|rigid:u7Tq4Bg9nRpH1HUHI6Sw/uARZrQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969R5 uniprotkb:Q8IWI9 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 intact:EBI-2815196|uniprotkb:E7ENI0|uniprotkb:F5H7K2|uniprotkb:Q9H9N7|uniprotkb:Q9H8R3|uniprotkb:Q9Y4E9|uniprotkb:Q9UG69|intact:EBI-11143500|intact:EBI-10969960|ensembl:ENSP00000219905|uniprotkb:B9EGR5 psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:mgap_human(display_long)|uniprotkb:MGA(gene name)|psi-mi:MGA(display_short)|uniprotkb:KIAA0518(gene name synonym)|uniprotkb:MAD5(gene name synonym)|uniprotkb:MAX dimerization protein 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833409|imex:IM-21659-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750|uniprotkb:Q969R5(identity)|entrezgene/locuslink:83746(identity)|ddbj/embl/genbank:BC017191(identity) refseq:NP_001074010.2|ensembl:ENSP00000219905|ensembl:ENST00000566586|ensembl:ENSP00000456141|ensembl:ENSG00000174197(gene)|ensembl:ENST00000219905(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR018186|interpro:IPR032060|interpro:IPR036638|interpro:IPR036960|interpro:IPR037935|mint:Q8IWI9|reactome:R-HSA-8953750|refseq:NP_001157745.1|dip:DIP-57615N|uniprotkb:Q8IWI9(identity)|entrezgene/locuslink:23269(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rogid:P4lo9EteCvikQQk5kyVkcobitLU9606 intact-crc:4E14595AB0781831|rigid:u7Tq4Bg9nRpH1HUHI6Sw/uARZrQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969R5 uniprotkb:P48643 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8 psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833409|imex:IM-21659-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750|uniprotkb:Q969R5(identity)|entrezgene/locuslink:83746(identity)|ddbj/embl/genbank:BC017191(identity) refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N|uniprotkb:P48643(identity)|entrezgene/locuslink:22948(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606 intact-crc:4E14595AB0781831|rigid:u7Tq4Bg9nRpH1HUHI6Sw/uARZrQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969R5 uniprotkb:O75461 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833409|imex:IM-21659-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750|uniprotkb:Q969R5(identity)|entrezgene/locuslink:83746(identity)|ddbj/embl/genbank:BC017191(identity) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 intact-crc:4E14595AB0781831|rigid:u7Tq4Bg9nRpH1HUHI6Sw/uARZrQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969R5 uniprotkb:P50990 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833409|imex:IM-21659-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750|uniprotkb:Q969R5(identity)|entrezgene/locuslink:83746(identity)|ddbj/embl/genbank:BC017191(identity) refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N|uniprotkb:P50990(identity)|entrezgene/locuslink:10694(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 intact-crc:4E14595AB0781831|rigid:u7Tq4Bg9nRpH1HUHI6Sw/uARZrQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969R5 uniprotkb:P17987 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334 psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833409|imex:IM-21659-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750|uniprotkb:Q969R5(identity)|entrezgene/locuslink:83746(identity)|ddbj/embl/genbank:BC017191(identity) refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N|uniprotkb:P17987(identity)|entrezgene/locuslink:6950(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606 intact-crc:4E14595AB0781831|rigid:u7Tq4Bg9nRpH1HUHI6Sw/uARZrQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969R5 uniprotkb:P50991 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958 psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833409|imex:IM-21659-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750|uniprotkb:Q969R5(identity)|entrezgene/locuslink:83746(identity)|ddbj/embl/genbank:BC017191(identity) refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998|uniprotkb:P50991(identity)|entrezgene/locuslink:10575(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606 intact-crc:4E14595AB0781831|rigid:u7Tq4Bg9nRpH1HUHI6Sw/uARZrQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969R5 uniprotkb:Q8IY57 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833409|imex:IM-21659-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750|uniprotkb:Q969R5(identity)|entrezgene/locuslink:83746(identity)|ddbj/embl/genbank:BC017191(identity) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|entrezgene/locuslink:10138(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 intact-crc:4E14595AB0781831|rigid:u7Tq4Bg9nRpH1HUHI6Sw/uARZrQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969R5 uniprotkb:P61244 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833409|imex:IM-21659-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750|uniprotkb:Q969R5(identity)|entrezgene/locuslink:83746(identity)|ddbj/embl/genbank:BC017191(identity) refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750|uniprotkb:P61244(identity)|entrezgene/locuslink:4149(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rogid:I5d1d/zT353OsLios95yEITNoWU9606 intact-crc:4E14595AB0781831|rigid:u7Tq4Bg9nRpH1HUHI6Sw/uARZrQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969R5 uniprotkb:Q99832 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091 psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833409|imex:IM-21659-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750|uniprotkb:Q969R5(identity)|entrezgene/locuslink:83746(identity)|ddbj/embl/genbank:BC017191(identity) dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|uniprotkb:Q99832(identity)|entrezgene/locuslink:10574(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606 intact-crc:4E14595AB0781831|rigid:u7Tq4Bg9nRpH1HUHI6Sw/uARZrQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969R5 uniprotkb:Q6MZP7 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 intact:EBI-1389411|uniprotkb:Q32M68|uniprotkb:Q32M69|uniprotkb:Q6N071|uniprotkb:Q76B60|ensembl:ENSP00000341947|ensembl:ENSP00000425844 psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:lin54_human(display_long)|uniprotkb:CXCDC1(gene name synonym)|uniprotkb:KIAA2037(gene name synonym)|uniprotkb:CXC domain-containing protein 1(gene name synonym)|uniprotkb:LIN54(gene name)|psi-mi:LIN54(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833409|imex:IM-21659-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750|uniprotkb:Q969R5(identity)|entrezgene/locuslink:83746(identity)|ddbj/embl/genbank:BC017191(identity) refseq:XP_006714144.1|refseq:NP_001108479.1|refseq:NP_001108480.1|refseq:NP_919258.2|refseq:XP_016863217.1|refseq:XP_016863218.1|refseq:XP_016863219.1|refseq:XP_005262807.1|refseq:NP_001275925.1|refseq:NP_001275926.1|ensembl:ENSG00000189308(gene)|ensembl:ENST00000340417(transcript)|ensembl:ENST00000505397(transcript)|go:"GO:0001067"(transcription regulatory region nucleic acid binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0046872"(metal ion binding)|interpro:IPR005172(Tesmin/TSO1-like, CXC)|interpro:IPR028307|interpro:IPR033467|mint:Q6MZP7|rcsb pdb:5FD3|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|uniprotkb:Q6MZP7(identity)|entrezgene/locuslink:132660(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rogid:RZwf5ctBfCw6s64KOOe8DkUmM609606 intact-crc:4E14595AB0781831|rigid:u7Tq4Bg9nRpH1HUHI6Sw/uARZrQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969R5 uniprotkb:Q9UHV9 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 intact:EBI-359873|uniprotkb:Q9P0P7|uniprotkb:Q9UN05|ensembl:ENSP00000356989 psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:pfd2_human(display_long)|uniprotkb:HSPC231(orf name)|uniprotkb:PFDN2(gene name)|psi-mi:PFDN2(display_short)|uniprotkb:PFD2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833409|imex:IM-21659-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750|uniprotkb:Q969R5(identity)|entrezgene/locuslink:83746(identity)|ddbj/embl/genbank:BC017191(identity) refseq:NP_036526.2|refseq:XP_011507926.1|ensembl:ENSG00000143256(gene)|ensembl:ENST00000368010(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|interpro:IPR027235|mint:Q9UHV9|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957|dip:DIP-27557N|uniprotkb:Q9UHV9(identity)|entrezgene/locuslink:5202(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rogid:rgr14h3vGyzHxHoNJtlHBQkvhUE9606 intact-crc:4E14595AB0781831|rigid:u7Tq4Bg9nRpH1HUHI6Sw/uARZrQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969R5 uniprotkb:P22528 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 intact:EBI-1058892|ensembl:ENSP00000306461|uniprotkb:B2R5H7|uniprotkb:P22529|uniprotkb:P22530|uniprotkb:Q5T524 psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:spr1b_human(display_long)|uniprotkb:SPRR1B(gene name)|psi-mi:SPRR1B(display_short)|uniprotkb:Small proline-rich protein IB(gene name synonym)|uniprotkb:14.9 kDa pancornulin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833409|imex:IM-21659-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750|uniprotkb:Q969R5(identity)|entrezgene/locuslink:83746(identity)|ddbj/embl/genbank:BC017191(identity) ensembl:ENSG00000169469(gene)|ensembl:ENST00000307098(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031424"(keratinization)|interpro:IPR003302("Cornifin (SPRR)")|mint:P22528|reactome:R-HSA-6809371|refseq:NP_003116.2|uniprotkb:P22528(identity)|entrezgene/locuslink:6699(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rogid:WU0vu+DHdIJm0x40HdcpAdJgdgo9606 intact-crc:4E14595AB0781831|rigid:u7Tq4Bg9nRpH1HUHI6Sw/uARZrQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JM7 uniprotkb:P62714 intact:EBI-2686809|uniprotkb:Q4VXE1|uniprotkb:Q6P9B5|uniprotkb:Q5VUM9|ensembl:ENSP00000354526|ensembl:ENSP00000357118 intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5 psi-mi:lmbl3_human(display_long)|uniprotkb:KIAA1798(gene name synonym)|uniprotkb:MBT1(gene name synonym)|uniprotkb:MBT-1(gene name synonym)|uniprotkb:L3MBTL3(gene name)|psi-mi:L3MBTL3(display_short) psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833543|imex:IM-21659-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011534481.1|refseq:XP_011534482.1|refseq:XP_011534483.1|refseq:XP_011534485.1|refseq:XP_011534486.1|refseq:NP_001007103.1|refseq:NP_115814.1|refseq:NP_001333480.1|refseq:NP_001333479.1|refseq:XP_005267218.1|refseq:XP_006715641.1|ensembl:ENSG00000198945(gene)|ensembl:ENST00000361794(transcript)|ensembl:ENST00000368136(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q96JM7|rcsb pdb:1WJQ|rcsb pdb:1WJS|rcsb pdb:3UT1|rcsb pdb:4FL6|rcsb pdb:4L59|go:"GO:0042802"(identical protein binding)|dip:DIP-42798N|uniprotkb:Q96JM7(identity)|ddbj/embl/genbank:BC060845(identity)|entrezgene/locuslink:84456(identity) refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N|uniprotkb:P62714(identity)|entrezgene/locuslink:5516(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:FYLlz+1Skg07Aw8gqXDVDFevaEg9606 rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606 intact-crc:406B797C2D68767F|rigid:6yQef49xiUgMFGiIXQIkmuOFvKg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JM7 uniprotkb:Q9H3G5 intact:EBI-2686809|uniprotkb:Q4VXE1|uniprotkb:Q6P9B5|uniprotkb:Q5VUM9|ensembl:ENSP00000354526|ensembl:ENSP00000357118 intact:EBI-357542|uniprotkb:Q6UX20|uniprotkb:Q8NBL7|uniprotkb:Q96AR7|uniprotkb:Q9HB41|ensembl:ENSP00000265394|ensembl:ENSP00000379572|ensembl:ENSP00000387164|intact:EBI-1058665|uniprotkb:A4D1A4 psi-mi:lmbl3_human(display_long)|uniprotkb:KIAA1798(gene name synonym)|uniprotkb:MBT1(gene name synonym)|uniprotkb:MBT-1(gene name synonym)|uniprotkb:L3MBTL3(gene name)|psi-mi:L3MBTL3(display_short) psi-mi:cpvl_human(display_long)|uniprotkb:CPVL(gene name)|psi-mi:CPVL(display_short)|uniprotkb:VLP(gene name synonym)|uniprotkb:UNQ197/PRO223(orf name)|uniprotkb:PSEC0124(orf name)|uniprotkb:Carboxypeptidase, vitellogenic-like(gene name synonym)|uniprotkb:Vitellogenic carboxypeptidase-like protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833543|imex:IM-21659-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011534481.1|refseq:XP_011534482.1|refseq:XP_011534483.1|refseq:XP_011534485.1|refseq:XP_011534486.1|refseq:NP_001007103.1|refseq:NP_115814.1|refseq:NP_001333480.1|refseq:NP_001333479.1|refseq:XP_005267218.1|refseq:XP_006715641.1|ensembl:ENSG00000198945(gene)|ensembl:ENST00000361794(transcript)|ensembl:ENST00000368136(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q96JM7|rcsb pdb:1WJQ|rcsb pdb:1WJS|rcsb pdb:3UT1|rcsb pdb:4FL6|rcsb pdb:4L59|go:"GO:0042802"(identical protein binding)|dip:DIP-42798N|uniprotkb:Q96JM7(identity)|ddbj/embl/genbank:BC060845(identity)|entrezgene/locuslink:84456(identity) ensembl:ENSG00000106066(gene)|ensembl:ENST00000265394(transcript)|ensembl:ENST00000396276(transcript)|ensembl:ENST00000409850(transcript)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR029058|mint:Q9H3G5|refseq:NP_061902.2|refseq:NP_112601.3|refseq:XP_011513739.1|refseq:NP_001334981.1|refseq:NP_001334983.1|uniprotkb:Q9H3G5(identity)|entrezgene/locuslink:54504(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:FYLlz+1Skg07Aw8gqXDVDFevaEg9606 rogid:antgab61u6D+KmbopQeowXqSqWQ9606 intact-crc:406B797C2D68767F|rigid:6yQef49xiUgMFGiIXQIkmuOFvKg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JM7 uniprotkb:Q5VXD3 intact:EBI-2686809|uniprotkb:Q4VXE1|uniprotkb:Q6P9B5|uniprotkb:Q5VUM9|ensembl:ENSP00000354526|ensembl:ENSP00000357118 intact:EBI-8833527|uniprotkb:Q5VXD4|uniprotkb:Q53AI4|uniprotkb:Q5VXD2|uniprotkb:D3DT11|uniprotkb:B3KPW8|ensembl:ENSP00000359705 psi-mi:lmbl3_human(display_long)|uniprotkb:KIAA1798(gene name synonym)|uniprotkb:MBT1(gene name synonym)|uniprotkb:MBT-1(gene name synonym)|uniprotkb:L3MBTL3(gene name)|psi-mi:L3MBTL3(display_short) psi-mi:sam13_human(display_long)|uniprotkb:HSD-42(orf name)|uniprotkb:HSD42(orf name)|uniprotkb:SAMD13(gene name)|psi-mi:SAMD13(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833543|imex:IM-21659-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011534481.1|refseq:XP_011534482.1|refseq:XP_011534483.1|refseq:XP_011534485.1|refseq:XP_011534486.1|refseq:NP_001007103.1|refseq:NP_115814.1|refseq:NP_001333480.1|refseq:NP_001333479.1|refseq:XP_005267218.1|refseq:XP_006715641.1|ensembl:ENSG00000198945(gene)|ensembl:ENST00000361794(transcript)|ensembl:ENST00000368136(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q96JM7|rcsb pdb:1WJQ|rcsb pdb:1WJS|rcsb pdb:3UT1|rcsb pdb:4FL6|rcsb pdb:4L59|go:"GO:0042802"(identical protein binding)|dip:DIP-42798N|uniprotkb:Q96JM7(identity)|ddbj/embl/genbank:BC060845(identity)|entrezgene/locuslink:84456(identity) refseq:XP_016855866.1|refseq:NP_001010971.1|refseq:NP_001128135.1|refseq:NP_001128136.1|ensembl:ENSG00000203943(gene)|ensembl:ENST00000370671(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q5VXD3|uniprotkb:Q5VXD3(identity)|entrezgene/locuslink:148418(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:FYLlz+1Skg07Aw8gqXDVDFevaEg9606 rogid:ssoQPKJU+FtnYlYhHX3S4GO/klU9606 intact-crc:406B797C2D68767F|rigid:6yQef49xiUgMFGiIXQIkmuOFvKg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JM7 uniprotkb:P13674 intact:EBI-2686809|uniprotkb:Q4VXE1|uniprotkb:Q6P9B5|uniprotkb:Q5VUM9|ensembl:ENSP00000354526|ensembl:ENSP00000357118 intact:EBI-1237386|uniprotkb:Q15082|uniprotkb:Q15083|uniprotkb:Q5VSQ5|uniprotkb:C9JL12|ensembl:ENSP00000307318|ensembl:ENSP00000378353 psi-mi:lmbl3_human(display_long)|uniprotkb:KIAA1798(gene name synonym)|uniprotkb:MBT1(gene name synonym)|uniprotkb:MBT-1(gene name synonym)|uniprotkb:L3MBTL3(gene name)|psi-mi:L3MBTL3(display_short) psi-mi:p4ha1_human(display_long)|uniprotkb:P4HA1(gene name)|psi-mi:P4HA1(display_short)|uniprotkb:P4HA(gene name synonym)|uniprotkb:Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833543|imex:IM-21659-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011534481.1|refseq:XP_011534482.1|refseq:XP_011534483.1|refseq:XP_011534485.1|refseq:XP_011534486.1|refseq:NP_001007103.1|refseq:NP_115814.1|refseq:NP_001333480.1|refseq:NP_001333479.1|refseq:XP_005267218.1|refseq:XP_006715641.1|ensembl:ENSG00000198945(gene)|ensembl:ENST00000361794(transcript)|ensembl:ENST00000368136(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q96JM7|rcsb pdb:1WJQ|rcsb pdb:1WJS|rcsb pdb:3UT1|rcsb pdb:4FL6|rcsb pdb:4L59|go:"GO:0042802"(identical protein binding)|dip:DIP-42798N|uniprotkb:Q96JM7(identity)|ddbj/embl/genbank:BC060845(identity)|entrezgene/locuslink:84456(identity) refseq:NP_000908.2|refseq:NP_001017962.1|refseq:NP_001136067.1|refseq:NP_001136068.1|dip:DIP-38180N|ensembl:ENSG00000122884(gene)|ensembl:ENST00000307116(transcript)|ensembl:ENST00000394890(transcript)|go:"GO:0004656"(procollagen-proline 4-dioxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0016222"(procollagen-proline 4-dioxygenase complex)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013547(Prolyl 4-hydroxylase alpha-subunit, N-terminal)|interpro:IPR019734|mint:P13674|rcsb pdb:1TJC|rcsb pdb:2V5F|rcsb pdb:2YQ8|rcsb pdb:4BT8|rcsb pdb:4BT9|rcsb pdb:4BTA|rcsb pdb:4BTB|reactome:R-HSA-1650814|go:"GO:0043231"(intracellular membrane-bounded organelle)|uniprotkb:P13674(identity)|entrezgene/locuslink:5033(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:FYLlz+1Skg07Aw8gqXDVDFevaEg9606 rogid:Yo9hgWVJ5iUGITVWKfvjhTNX1lk9606 intact-crc:406B797C2D68767F|rigid:6yQef49xiUgMFGiIXQIkmuOFvKg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JM7 uniprotkb:Q9BQE3 intact:EBI-2686809|uniprotkb:Q4VXE1|uniprotkb:Q6P9B5|uniprotkb:Q5VUM9|ensembl:ENSP00000354526|ensembl:ENSP00000357118 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:lmbl3_human(display_long)|uniprotkb:KIAA1798(gene name synonym)|uniprotkb:MBT1(gene name synonym)|uniprotkb:MBT-1(gene name synonym)|uniprotkb:L3MBTL3(gene name)|psi-mi:L3MBTL3(display_short) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833543|imex:IM-21659-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011534481.1|refseq:XP_011534482.1|refseq:XP_011534483.1|refseq:XP_011534485.1|refseq:XP_011534486.1|refseq:NP_001007103.1|refseq:NP_115814.1|refseq:NP_001333480.1|refseq:NP_001333479.1|refseq:XP_005267218.1|refseq:XP_006715641.1|ensembl:ENSG00000198945(gene)|ensembl:ENST00000361794(transcript)|ensembl:ENST00000368136(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q96JM7|rcsb pdb:1WJQ|rcsb pdb:1WJS|rcsb pdb:3UT1|rcsb pdb:4FL6|rcsb pdb:4L59|go:"GO:0042802"(identical protein binding)|dip:DIP-42798N|uniprotkb:Q96JM7(identity)|ddbj/embl/genbank:BC060845(identity)|entrezgene/locuslink:84456(identity) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1|uniprotkb:Q9BQE3(identity)|entrezgene/locuslink:84790(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:FYLlz+1Skg07Aw8gqXDVDFevaEg9606 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:406B797C2D68767F|rigid:6yQef49xiUgMFGiIXQIkmuOFvKg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JM7 uniprotkb:Q9UHJ3 intact:EBI-2686809|uniprotkb:Q4VXE1|uniprotkb:Q6P9B5|uniprotkb:Q5VUM9|ensembl:ENSP00000354526|ensembl:ENSP00000357118 intact:EBI-747398|uniprotkb:Q96C73|uniprotkb:Q9Y4Q9|uniprotkb:Q402F7|ensembl:ENSP00000378235 psi-mi:lmbl3_human(display_long)|uniprotkb:KIAA1798(gene name synonym)|uniprotkb:MBT1(gene name synonym)|uniprotkb:MBT-1(gene name synonym)|uniprotkb:L3MBTL3(gene name)|psi-mi:L3MBTL3(display_short) psi-mi:smbt1_human(display_long)|uniprotkb:Renal ubiquitous protein 1(gene name synonym)|uniprotkb:SFMBT1(gene name)|psi-mi:SFMBT1(display_short)|uniprotkb:RU1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833543|imex:IM-21659-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011534481.1|refseq:XP_011534482.1|refseq:XP_011534483.1|refseq:XP_011534485.1|refseq:XP_011534486.1|refseq:NP_001007103.1|refseq:NP_115814.1|refseq:NP_001333480.1|refseq:NP_001333479.1|refseq:XP_005267218.1|refseq:XP_006715641.1|ensembl:ENSG00000198945(gene)|ensembl:ENST00000361794(transcript)|ensembl:ENST00000368136(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q96JM7|rcsb pdb:1WJQ|rcsb pdb:1WJS|rcsb pdb:3UT1|rcsb pdb:4FL6|rcsb pdb:4L59|go:"GO:0042802"(identical protein binding)|dip:DIP-42798N|uniprotkb:Q96JM7(identity)|ddbj/embl/genbank:BC060845(identity)|entrezgene/locuslink:84456(identity) refseq:XP_006713266.1|refseq:XP_006713267.1|refseq:NP_057413.2|refseq:XP_011532126.1|refseq:XP_011532127.1|refseq:XP_005265278.1|ensembl:ENSG00000163935(gene)|ensembl:ENST00000394752(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048635"(negative regulation of muscle organ development)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR037604|interpro:IPR038348|mint:Q9UHJ3|uniprotkb:Q9UHJ3(identity)|entrezgene/locuslink:51460(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:FYLlz+1Skg07Aw8gqXDVDFevaEg9606 rogid:vh/dDMpcLQEo57Wcjnggufh6HRk9606 intact-crc:406B797C2D68767F|rigid:6yQef49xiUgMFGiIXQIkmuOFvKg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JM7 uniprotkb:Q6SPF0 intact:EBI-2686809|uniprotkb:Q4VXE1|uniprotkb:Q6P9B5|uniprotkb:Q5VUM9|ensembl:ENSP00000354526|ensembl:ENSP00000357118 intact:EBI-8833536|uniprotkb:Q96IM4|uniprotkb:Q6PIS7|uniprotkb:Q6P0R3 psi-mi:lmbl3_human(display_long)|uniprotkb:KIAA1798(gene name synonym)|uniprotkb:MBT1(gene name synonym)|uniprotkb:MBT-1(gene name synonym)|uniprotkb:L3MBTL3(gene name)|psi-mi:L3MBTL3(display_short) psi-mi:samd1_human(display_long)|uniprotkb:SAMD1(gene name)|psi-mi:SAMD1(display_short)|uniprotkb:Atherin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833543|imex:IM-21659-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011534481.1|refseq:XP_011534482.1|refseq:XP_011534483.1|refseq:XP_011534485.1|refseq:XP_011534486.1|refseq:NP_001007103.1|refseq:NP_115814.1|refseq:NP_001333480.1|refseq:NP_001333479.1|refseq:XP_005267218.1|refseq:XP_006715641.1|ensembl:ENSG00000198945(gene)|ensembl:ENST00000361794(transcript)|ensembl:ENST00000368136(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q96JM7|rcsb pdb:1WJQ|rcsb pdb:1WJS|rcsb pdb:3UT1|rcsb pdb:4FL6|rcsb pdb:4L59|go:"GO:0042802"(identical protein binding)|dip:DIP-42798N|uniprotkb:Q96JM7(identity)|ddbj/embl/genbank:BC060845(identity)|entrezgene/locuslink:84456(identity) mint:Q6SPF0|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_612361.1|go:"GO:0005737"(cytoplasm)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|rcsb pdb:6LUI|rcsb pdb:6LUJ|rcsb pdb:6LUK|go:"GO:0003682"(chromatin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|uniprotkb:Q6SPF0(identity)|entrezgene/locuslink:90378(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:FYLlz+1Skg07Aw8gqXDVDFevaEg9606 rogid:Cav/ZfHiZJ1xCBI6jAYrzv+CmZ49606 intact-crc:406B797C2D68767F|rigid:6yQef49xiUgMFGiIXQIkmuOFvKg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NA19 uniprotkb:O14818 intact:EBI-8833581|uniprotkb:A8MTL8|uniprotkb:Q8IXS3|ensembl:ENSP00000382976 intact:EBI-603272|uniprotkb:Q9BR53|uniprotkb:Q9H4K5|uniprotkb:Q9UEU8|uniprotkb:B2R515|uniprotkb:Q5JXJ2|ensembl:ENSP00000359910 psi-mi:lmbl4_human(display_long)|uniprotkb:L3MBTL4(gene name)|psi-mi:L3MBTL4(display_short) psi-mi:psa7_human(display_long)|uniprotkb:PSMA7(gene name)|psi-mi:PSMA7(display_short)|uniprotkb:Proteasome subunit RC6-1(gene name synonym)|uniprotkb:Proteasome subunit XAPC7(gene name synonym)|uniprotkb:HSPC(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833595|imex:IM-21659-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524063.1|refseq:NP_775735.2|ensembl:ENSG00000154655(gene)|ensembl:ENST00000400105(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q8NA19|interpro:IPR002515(Zinc finger, C2HC-type)|uniprotkb:Q8NA19(identity)|entrezgene/locuslink:91133(identity)|ddbj/embl/genbank:BC039316(identity) refseq:NP_002783.1|dip:DIP-29363N|ensembl:ENSG00000101182(gene)|ensembl:ENST00000370873(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098794"(postsynapse)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035190|mint:O14818|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|uniprotkb:O14818(identity)|entrezgene/locuslink:5688(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:3aoPBOJi3Hx/m4yM6uJ6h73p5949606 rogid:J1M+b+VK02BAn2OnZISjjlmO8dc9606 intact-crc:4D89005EAB9DB5E2|rigid:A7XgQzlRbQFjKrV3LVVHSLPgBMs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NA19 uniprotkb:Q9NRA1 intact:EBI-8833581|uniprotkb:A8MTL8|uniprotkb:Q8IXS3|ensembl:ENSP00000382976 intact:EBI-8833587|uniprotkb:B4DU34|uniprotkb:Q4W5M9|uniprotkb:Q9UL22|uniprotkb:B9EGR8|ensembl:ENSP00000422464 psi-mi:lmbl4_human(display_long)|uniprotkb:L3MBTL4(gene name)|psi-mi:L3MBTL4(display_short) psi-mi:pdgfc_human(display_long)|uniprotkb:Fallotein(gene name synonym)|uniprotkb:SCDGF(gene name synonym)|uniprotkb:Spinal cord-derived growth factor(gene name synonym)|uniprotkb:VEGF-E(gene name synonym)|uniprotkb:UNQ174/PRO200(orf name)|uniprotkb:PDGFC(gene name)|psi-mi:PDGFC(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833595|imex:IM-21659-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524063.1|refseq:NP_775735.2|ensembl:ENSG00000154655(gene)|ensembl:ENST00000400105(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q8NA19|interpro:IPR002515(Zinc finger, C2HC-type)|uniprotkb:Q8NA19(identity)|entrezgene/locuslink:91133(identity)|ddbj/embl/genbank:BC039316(identity) refseq:XP_016863945.1|refseq:NP_057289.1|dip:DIP-59339N|ensembl:ENSG00000145431(gene)|ensembl:ENST00000502773(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005161"(platelet-derived growth factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007171"(activation of transmembrane receptor protein tyrosine kinase activity)|go:"GO:0007417"(central nervous system development)|go:"GO:0008083"(growth factor activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048565"(digestive tract development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0060348"(bone development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000072("Platelet-derived growth factor (PDGF)")|interpro:IPR000859(CUB)|interpro:IPR029034|interpro:IPR029817|interpro:IPR035914|reactome:R-HSA-186797|uniprotkb:Q9NRA1(identity)|entrezgene/locuslink:56034(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:3aoPBOJi3Hx/m4yM6uJ6h73p5949606 rogid:q61aPBV3efRYCOLKThu9ppVFNqY9606 intact-crc:4D89005EAB9DB5E2|rigid:A7XgQzlRbQFjKrV3LVVHSLPgBMs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NA19 uniprotkb:P28074 intact:EBI-8833581|uniprotkb:A8MTL8|uniprotkb:Q8IXS3|ensembl:ENSP00000382976 intact:EBI-357828|uniprotkb:Q16242|uniprotkb:Q6PEW2|intact:EBI-1237472|uniprotkb:Q7Z3B5|uniprotkb:Q9TNN9|uniprotkb:B2R4N9|uniprotkb:D3DS43|uniprotkb:B4DUM9|uniprotkb:Q86T01|uniprotkb:E9PAV2|ensembl:ENSP00000355325 psi-mi:lmbl4_human(display_long)|uniprotkb:L3MBTL4(gene name)|psi-mi:L3MBTL4(display_short) psi-mi:psb5_human(display_long)|uniprotkb:PSMB5(gene name)|psi-mi:PSMB5(display_short)|uniprotkb:LMPX(gene name synonym)|uniprotkb:Proteasome epsilon chain(gene name synonym)|uniprotkb:Macropain epsilon chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex epsilon chain(gene name synonym)|uniprotkb:Proteasome subunit X(gene name synonym)|uniprotkb:Proteasome chain 6(gene name synonym)|uniprotkb:Proteasome subunit MB1(gene name synonym)|uniprotkb:MB1(gene name synonym)|uniprotkb:X(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833595|imex:IM-21659-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524063.1|refseq:NP_775735.2|ensembl:ENSG00000154655(gene)|ensembl:ENST00000400105(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q8NA19|interpro:IPR002515(Zinc finger, C2HC-type)|uniprotkb:Q8NA19(identity)|entrezgene/locuslink:91133(identity)|ddbj/embl/genbank:BC039316(identity) refseq:NP_001124197.1|refseq:NP_001138404.1|refseq:NP_002788.1|dip:DIP-27540N|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5610785|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|ensembl:ENSG00000100804(gene)|ensembl:ENST00000361611(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006508"(proteolysis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008233"(peptidase activity)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|mint:P28074|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|uniprotkb:P28074(identity)|entrezgene/locuslink:5693(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:3aoPBOJi3Hx/m4yM6uJ6h73p5949606 rogid:73T59wniLri/465F3BhBvwL1/LM9606 intact-crc:4D89005EAB9DB5E2|rigid:A7XgQzlRbQFjKrV3LVVHSLPgBMs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NA19 uniprotkb:P62191 intact:EBI-8833581|uniprotkb:A8MTL8|uniprotkb:Q8IXS3|ensembl:ENSP00000382976 intact:EBI-357598|uniprotkb:P49014|uniprotkb:Q03527|uniprotkb:Q6IAW0|uniprotkb:Q96AZ3|ensembl:ENSP00000261303|uniprotkb:Q6NW36|uniprotkb:B4DR63 psi-mi:lmbl4_human(display_long)|uniprotkb:L3MBTL4(gene name)|psi-mi:L3MBTL4(display_short) psi-mi:prs4_human(display_long)|uniprotkb:PSMC1(gene name)|psi-mi:PSMC1(display_short)|uniprotkb:26S proteasome AAA-ATPase subunit RPT2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833595|imex:IM-21659-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524063.1|refseq:NP_775735.2|ensembl:ENSG00000154655(gene)|ensembl:ENST00000400105(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q8NA19|interpro:IPR002515(Zinc finger, C2HC-type)|uniprotkb:Q8NA19(identity)|entrezgene/locuslink:91133(identity)|ddbj/embl/genbank:BC039316(identity) refseq:NP_002793.2|ensembl:ENST00000261303(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|ensembl:ENSG00000100764(gene)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|mint:P62191|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFQ|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-8852276|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|refseq:NP_001317141.1|refseq:XP_016876959.1|uniprotkb:P62191(identity)|entrezgene/locuslink:5700(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:3aoPBOJi3Hx/m4yM6uJ6h73p5949606 rogid:oGEtU7Cv0qversbD3WQgAo5H9pM9606 intact-crc:4D89005EAB9DB5E2|rigid:A7XgQzlRbQFjKrV3LVVHSLPgBMs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NA19 uniprotkb:Q96JM7 intact:EBI-8833581|uniprotkb:A8MTL8|uniprotkb:Q8IXS3|ensembl:ENSP00000382976 intact:EBI-2686809|uniprotkb:Q4VXE1|uniprotkb:Q6P9B5|uniprotkb:Q5VUM9|ensembl:ENSP00000354526|ensembl:ENSP00000357118 psi-mi:lmbl4_human(display_long)|uniprotkb:L3MBTL4(gene name)|psi-mi:L3MBTL4(display_short) psi-mi:lmbl3_human(display_long)|uniprotkb:KIAA1798(gene name synonym)|uniprotkb:MBT1(gene name synonym)|uniprotkb:MBT-1(gene name synonym)|uniprotkb:L3MBTL3(gene name)|psi-mi:L3MBTL3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833595|imex:IM-21659-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524063.1|refseq:NP_775735.2|ensembl:ENSG00000154655(gene)|ensembl:ENST00000400105(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q8NA19|interpro:IPR002515(Zinc finger, C2HC-type)|uniprotkb:Q8NA19(identity)|entrezgene/locuslink:91133(identity)|ddbj/embl/genbank:BC039316(identity) refseq:XP_011534481.1|refseq:XP_011534482.1|refseq:XP_011534483.1|refseq:XP_011534485.1|refseq:XP_011534486.1|refseq:NP_001007103.1|refseq:NP_115814.1|refseq:NP_001333480.1|refseq:NP_001333479.1|refseq:XP_005267218.1|refseq:XP_006715641.1|ensembl:ENSG00000198945(gene)|ensembl:ENST00000361794(transcript)|ensembl:ENST00000368136(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q96JM7|rcsb pdb:1WJQ|rcsb pdb:1WJS|rcsb pdb:3UT1|rcsb pdb:4FL6|rcsb pdb:4L59|go:"GO:0042802"(identical protein binding)|dip:DIP-42798N|uniprotkb:Q96JM7(identity)|entrezgene/locuslink:84456(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:3aoPBOJi3Hx/m4yM6uJ6h73p5949606 rogid:FYLlz+1Skg07Aw8gqXDVDFevaEg9606 intact-crc:4D89005EAB9DB5E2|rigid:A7XgQzlRbQFjKrV3LVVHSLPgBMs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NA19 uniprotkb:P28066 intact:EBI-8833581|uniprotkb:A8MTL8|uniprotkb:Q8IXS3|ensembl:ENSP00000382976 intact:EBI-355475|uniprotkb:B4E2V4|uniprotkb:Q6IBF7|uniprotkb:Q3T1C1|uniprotkb:B2R8F6|ensembl:ENSP00000271308 psi-mi:lmbl4_human(display_long)|uniprotkb:L3MBTL4(gene name)|psi-mi:L3MBTL4(display_short) psi-mi:psa5_human(display_long)|uniprotkb:PSMA5(gene name)|psi-mi:PSMA5(display_short)|uniprotkb:Proteasome zeta chain(gene name synonym)|uniprotkb:Macropain zeta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex zeta chain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833595|imex:IM-21659-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524063.1|refseq:NP_775735.2|ensembl:ENSG00000154655(gene)|ensembl:ENST00000400105(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q8NA19|interpro:IPR002515(Zinc finger, C2HC-type)|uniprotkb:Q8NA19(identity)|entrezgene/locuslink:91133(identity)|ddbj/embl/genbank:BC039316(identity) refseq:NP_001186701.1|refseq:NP_001186702.1|refseq:NP_001186703.1|refseq:NP_002781.2|ensembl:ENSG00000143106(gene)|ensembl:ENST00000271308(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR033812|mint:P28066|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEY|rcsb pdb:5LEX|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-29368N|uniprotkb:P28066(identity)|entrezgene/locuslink:5686(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:3aoPBOJi3Hx/m4yM6uJ6h73p5949606 rogid:bfMG3npzVetUH1tahr2MAI4R+3g9606 intact-crc:4D89005EAB9DB5E2|rigid:A7XgQzlRbQFjKrV3LVVHSLPgBMs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NA19 uniprotkb:P62891 intact:EBI-8833581|uniprotkb:A8MTL8|uniprotkb:Q8IXS3|ensembl:ENSP00000382976 intact:EBI-8830744|uniprotkb:P02404|uniprotkb:Q9BYF2|uniprotkb:P39025|ensembl:ENSP00000355315 psi-mi:lmbl4_human(display_long)|uniprotkb:L3MBTL4(gene name)|psi-mi:L3MBTL4(display_short) psi-mi:rl39_human(display_long)|uniprotkb:RPL39(gene name)|psi-mi:RPL39(display_short)|uniprotkb:Large ribosomal subunit protein eL39(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833595|imex:IM-21659-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524063.1|refseq:NP_775735.2|ensembl:ENSG00000154655(gene)|ensembl:ENST00000400105(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q8NA19|interpro:IPR002515(Zinc finger, C2HC-type)|uniprotkb:Q8NA19(identity)|entrezgene/locuslink:91133(identity)|ddbj/embl/genbank:BC039316(identity) refseq:NP_000991.1|rcsb pdb:4V6X|ensembl:ENSG00000198918(gene)|ensembl:ENST00000361575(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000077(Ribosomal protein L39e)|interpro:IPR020083|interpro:IPR023626|rcsb pdb:4UG0|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|uniprotkb:P62891(identity)|entrezgene/locuslink:6170(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:3aoPBOJi3Hx/m4yM6uJ6h73p5949606 rogid:AZus2dxwJsTxAOwnJ93E2yhasbo9606 intact-crc:4D89005EAB9DB5E2|rigid:A7XgQzlRbQFjKrV3LVVHSLPgBMs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NA19 uniprotkb:P28072 intact:EBI-8833581|uniprotkb:A8MTL8|uniprotkb:Q8IXS3|ensembl:ENSP00000382976 intact:EBI-359288|uniprotkb:Q96J55|ensembl:ENSP00000270586 psi-mi:lmbl4_human(display_long)|uniprotkb:L3MBTL4(gene name)|psi-mi:L3MBTL4(display_short) psi-mi:psb6_human(display_long)|uniprotkb:PSMB6(gene name)|psi-mi:PSMB6(display_short)|uniprotkb:LMPY(gene name synonym)|uniprotkb:Proteasome delta chain(gene name synonym)|uniprotkb:Macropain delta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex delta chain(gene name synonym)|uniprotkb:Proteasome subunit Y(gene name synonym)|uniprotkb:Y(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833595|imex:IM-21659-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524063.1|refseq:NP_775735.2|ensembl:ENSG00000154655(gene)|ensembl:ENST00000400105(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q8NA19|interpro:IPR002515(Zinc finger, C2HC-type)|uniprotkb:Q8NA19(identity)|entrezgene/locuslink:91133(identity)|ddbj/embl/genbank:BC039316(identity) refseq:NP_002789.1|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035140|mint:P28072|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|go:"GO:0005737"(cytoplasm)|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000142507(gene)|ensembl:ENST00000270586(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-33847N|uniprotkb:P28072(identity)|entrezgene/locuslink:5694(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:3aoPBOJi3Hx/m4yM6uJ6h73p5949606 rogid:4LRxYA6/tM2hsc96iP29c5J7ew49606 intact-crc:4D89005EAB9DB5E2|rigid:A7XgQzlRbQFjKrV3LVVHSLPgBMs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61244 uniprotkb:Q99583 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 intact:EBI-7959025|uniprotkb:D3DTI7|uniprotkb:A8K6D1|intact:MINT-7969172|uniprotkb:Q1ED38|ensembl:ENSP00000174618 psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:mnt_human(display_long)|uniprotkb:MNT(gene name)|psi-mi:MNT(display_short)|uniprotkb:BHLHD3(gene name synonym)|uniprotkb:ROX(gene name synonym)|uniprotkb:Protein ROX(gene name synonym)|uniprotkb:Myc antagonist MNT(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833645|imex:IM-21659-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750|uniprotkb:P61244(identity)|entrezgene/locuslink:4149(identity)|ddbj/embl/genbank:BC036092(identity) refseq:NP_064706.1|ensembl:ENSG00000070444(gene)|ensembl:ENST00000174618(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007569"(cell aging)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|uniprotkb:Q99583(identity)|entrezgene/locuslink:4335(identity) psi-mi:"MI:0469"(intact) - comment:mint figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:I5d1d/zT353OsLios95yEITNoWU9606 rogid:JfylNX5Z5fICBKl7eodHpCL2J2U9606 intact-crc:8C5CF596752666A6|rigid:5cazm7lp0VJyNlB2E2uCjthIBs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61244 uniprotkb:P22528 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 intact:EBI-1058892|ensembl:ENSP00000306461|uniprotkb:B2R5H7|uniprotkb:P22529|uniprotkb:P22530|uniprotkb:Q5T524 psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:spr1b_human(display_long)|uniprotkb:SPRR1B(gene name)|psi-mi:SPRR1B(display_short)|uniprotkb:Small proline-rich protein IB(gene name synonym)|uniprotkb:14.9 kDa pancornulin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833645|imex:IM-21659-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750|uniprotkb:P61244(identity)|entrezgene/locuslink:4149(identity)|ddbj/embl/genbank:BC036092(identity) ensembl:ENSG00000169469(gene)|ensembl:ENST00000307098(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031424"(keratinization)|interpro:IPR003302("Cornifin (SPRR)")|mint:P22528|reactome:R-HSA-6809371|refseq:NP_003116.2|uniprotkb:P22528(identity)|entrezgene/locuslink:6699(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:I5d1d/zT353OsLios95yEITNoWU9606 rogid:WU0vu+DHdIJm0x40HdcpAdJgdgo9606 intact-crc:8C5CF596752666A6|rigid:5cazm7lp0VJyNlB2E2uCjthIBs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61244 uniprotkb:Q9BYE7 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833645|imex:IM-21659-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750|uniprotkb:P61244(identity)|entrezgene/locuslink:4149(identity)|ddbj/embl/genbank:BC036092(identity) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:I5d1d/zT353OsLios95yEITNoWU9606 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 intact-crc:8C5CF596752666A6|rigid:5cazm7lp0VJyNlB2E2uCjthIBs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61244 uniprotkb:Q14186 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833645|imex:IM-21659-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750|uniprotkb:P61244(identity)|entrezgene/locuslink:4149(identity)|ddbj/embl/genbank:BC036092(identity) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|entrezgene/locuslink:7027(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:I5d1d/zT353OsLios95yEITNoWU9606 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 intact-crc:8C5CF596752666A6|rigid:5cazm7lp0VJyNlB2E2uCjthIBs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61244 uniprotkb:P61964 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833645|imex:IM-21659-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750|uniprotkb:P61244(identity)|entrezgene/locuslink:4149(identity)|ddbj/embl/genbank:BC036092(identity) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|entrezgene/locuslink:11091(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:I5d1d/zT353OsLios95yEITNoWU9606 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 intact-crc:8C5CF596752666A6|rigid:5cazm7lp0VJyNlB2E2uCjthIBs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61244 uniprotkb:Q05195 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 intact:EBI-8833637|uniprotkb:Q6FI41|uniprotkb:D6W5G2|uniprotkb:B2R6V8|uniprotkb:B7ZLI6|ensembl:ENSP00000264444 psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:mad1_human(display_long)|uniprotkb:MAD(gene name synonym)|uniprotkb:Protein MAD(gene name synonym)|uniprotkb:MXD1(gene name)|psi-mi:MXD1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833645|imex:IM-21659-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750|uniprotkb:P61244(identity)|entrezgene/locuslink:4149(identity)|ddbj/embl/genbank:BC036092(identity) refseq:NP_001189442.1|refseq:NP_001189443.1|refseq:NP_002348.1|dip:DIP-204N|ensembl:ENSG00000059728(gene)|ensembl:ENST00000264444(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR040157|mint:Q05195|rcsb pdb:1E91|rcsb pdb:1G1E|rcsb pdb:1NLW|rcsb pdb:1PD7|rcsb pdb:1S5Q|entrezgene/locuslink:4084(identity)|uniprotkb:Q05195(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:I5d1d/zT353OsLios95yEITNoWU9606 rogid:s9svBcYiX+lDX90aL1zzgy428Ao9606 intact-crc:8C5CF596752666A6|rigid:5cazm7lp0VJyNlB2E2uCjthIBs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61244 uniprotkb:Q9UKB1 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 intact:EBI-355189|uniprotkb:Q9P2S8|uniprotkb:Q9P2S9|uniprotkb:Q9Y4C6|uniprotkb:B2RC98|ensembl:ENSP00000265094 psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:fbw1b_human(display_long)|uniprotkb:KIAA0696(gene name synonym)|uniprotkb:FBXW11(gene name)|psi-mi:FBXW11(display_short)|uniprotkb:BTRCP2(gene name synonym)|uniprotkb:FBW1B(gene name synonym)|uniprotkb:FBXW1B(gene name synonym)|uniprotkb:F-box/WD repeat-containing protein 1B(gene name synonym)|uniprotkb:F-box and WD repeats protein beta-TrCP2(gene name synonym)|uniprotkb:Homologous to Slimb protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833645|imex:IM-21659-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750|uniprotkb:P61244(identity)|entrezgene/locuslink:4149(identity)|ddbj/embl/genbank:BC036092(identity) refseq:NP_036432.2|refseq:NP_387448.2|refseq:NP_387449.2|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007097"(nuclear migration)|go:"GO:0007281"(germ cell development)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031648"(protein destabilization)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0005635"(nuclear envelope)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0070840"(dynein complex binding)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021977|interpro:IPR036047|interpro:IPR036322|mint:Q9UKB1|rcsb pdb:6WNX|reactome:R-HSA-1169091|reactome:R-HSA-202424|reactome:R-HSA-2565942|reactome:R-HSA-2871837|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-8951664|reactome:R-HSA-983168|go:"GO:0048511"(rhythmic process)|ensembl:ENSG00000072803(gene)|ensembl:ENST00000265094(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000776"(kinetochore)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|dip:DIP-27593N|uniprotkb:Q9UKB1(identity)|entrezgene/locuslink:23291(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:I5d1d/zT353OsLios95yEITNoWU9606 rogid:8wLc2Pt+mLfRsNwXOnjho+1A0u09606 intact-crc:8C5CF596752666A6|rigid:5cazm7lp0VJyNlB2E2uCjthIBs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61244 uniprotkb:Q06587 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833645|imex:IM-21659-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750|uniprotkb:P61244(identity)|entrezgene/locuslink:4149(identity)|ddbj/embl/genbank:BC036092(identity) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:I5d1d/zT353OsLios95yEITNoWU9606 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 intact-crc:8C5CF596752666A6|rigid:5cazm7lp0VJyNlB2E2uCjthIBs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61244 uniprotkb:Q96IC2 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 intact:EBI-3918878|uniprotkb:Q9BXH9|uniprotkb:Q96MB1|uniprotkb:O60364|uniprotkb:Q9H0K2|uniprotkb:B2RB19|uniprotkb:Q9NSM2|ensembl:ENSP00000261377|ensembl:ENSP00000457616 psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:rexo5_human(display_long)|uniprotkb:REXO5(gene name)|psi-mi:REXO5(display_short)|uniprotkb:Exonuclease NEF-sp(gene name synonym)|uniprotkb:44M2.3(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833645|imex:IM-21659-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750|uniprotkb:P61244(identity)|entrezgene/locuslink:4149(identity)|ddbj/embl/genbank:BC036092(identity) refseq:XP_011544265.1|refseq:NP_001138396.1|refseq:NP_001185982.1|refseq:NP_112203.2|refseq:XP_005255661.1|refseq:XP_016879228.1|ensembl:ENSG00000005189(gene)|ensembl:ENST00000261377(transcript)|ensembl:ENST00000564274(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013520(Exonuclease, RNase T and DNA polymerase III)|interpro:IPR034922|interpro:IPR035979|interpro:IPR036397|uniprotkb:Q96IC2(identity)|entrezgene/locuslink:81691(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:I5d1d/zT353OsLios95yEITNoWU9606 rogid:96pyEAvicDQ3/nFJ2wMWFqrSsA09606 intact-crc:8C5CF596752666A6|rigid:5cazm7lp0VJyNlB2E2uCjthIBs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61244 uniprotkb:Q8IWI9 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 intact:EBI-2815196|uniprotkb:E7ENI0|uniprotkb:F5H7K2|uniprotkb:Q9H9N7|uniprotkb:Q9H8R3|uniprotkb:Q9Y4E9|uniprotkb:Q9UG69|intact:EBI-11143500|intact:EBI-10969960|ensembl:ENSP00000219905|uniprotkb:B9EGR5 psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:mgap_human(display_long)|uniprotkb:MGA(gene name)|psi-mi:MGA(display_short)|uniprotkb:KIAA0518(gene name synonym)|uniprotkb:MAD5(gene name synonym)|uniprotkb:MAX dimerization protein 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833645|imex:IM-21659-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750|uniprotkb:P61244(identity)|entrezgene/locuslink:4149(identity)|ddbj/embl/genbank:BC036092(identity) refseq:NP_001074010.2|ensembl:ENSP00000219905|ensembl:ENST00000566586|ensembl:ENSP00000456141|ensembl:ENSG00000174197(gene)|ensembl:ENST00000219905(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR018186|interpro:IPR032060|interpro:IPR036638|interpro:IPR036960|interpro:IPR037935|mint:Q8IWI9|reactome:R-HSA-8953750|refseq:NP_001157745.1|dip:DIP-57615N|uniprotkb:Q8IWI9(identity)|entrezgene/locuslink:23269(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:I5d1d/zT353OsLios95yEITNoWU9606 rogid:P4lo9EteCvikQQk5kyVkcobitLU9606 intact-crc:8C5CF596752666A6|rigid:5cazm7lp0VJyNlB2E2uCjthIBs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61244 uniprotkb:O75461 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833645|imex:IM-21659-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750|uniprotkb:P61244(identity)|entrezgene/locuslink:4149(identity)|ddbj/embl/genbank:BC036092(identity) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:I5d1d/zT353OsLios95yEITNoWU9606 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 intact-crc:8C5CF596752666A6|rigid:5cazm7lp0VJyNlB2E2uCjthIBs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61244 uniprotkb:Q99496 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833645|imex:IM-21659-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750|uniprotkb:P61244(identity)|entrezgene/locuslink:4149(identity)|ddbj/embl/genbank:BC036092(identity) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|entrezgene/locuslink:6045(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:I5d1d/zT353OsLios95yEITNoWU9606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 intact-crc:8C5CF596752666A6|rigid:5cazm7lp0VJyNlB2E2uCjthIBs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61244 uniprotkb:P05089 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 intact:EBI-2513844|uniprotkb:Q5JWT6|uniprotkb:Q5JWT5|uniprotkb:Q9BS50|uniprotkb:Q8TE72|uniprotkb:A6NEA0|ensembl:ENSP00000357066 psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:argi1_human(display_long)|uniprotkb:ARG1(gene name)|psi-mi:ARG1(display_short)|uniprotkb:Type I arginase(gene name synonym)|uniprotkb:Liver-type arginase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833645|imex:IM-21659-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750|uniprotkb:P61244(identity)|entrezgene/locuslink:4149(identity)|ddbj/embl/genbank:BC036092(identity) refseq:NP_000036.2|refseq:NP_001231367.1|ensembl:ENSG00000118520(gene)|ensembl:ENST00000368087(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0001889"(liver development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004053"(arginase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006527"(arginine catabolic process)|go:"GO:0007568"(aging)|go:"GO:0009635"(response to herbicide)|go:"GO:0010042"(response to manganese ion)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010963"|go:"GO:0014075"(response to amine)|go:"GO:0019547"(arginine catabolic process to ornithine)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030324"(lung development)|go:"GO:0032964"(collagen biosynthetic process)|go:"GO:0033189"(response to vitamin A)|go:"GO:0033197"(response to vitamin E)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043200"(response to amino acid)|go:"GO:0045087"(innate immune response)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048678"(response to axon injury)|go:"GO:0051597"(response to methylmercury)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070965"(positive regulation of neutrophil mediated killing of fungus)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071377"(cellular response to glucagon stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:2000552"(negative regulation of T-helper 2 cell cytokine production)|interpro:IPR006035(Ureohydrolase)|interpro:IPR014033(Arginase, subgroup)|go:"GO:0060056"(mammary gland involution)|interpro:IPR020855|interpro:IPR023696|mint:P05089|rcsb pdb:1WVA|rcsb pdb:1WVB|rcsb pdb:2AEB|rcsb pdb:2PHA|rcsb pdb:2PHO|rcsb pdb:2PLL|rcsb pdb:2ZAV|rcsb pdb:3DJ8|rcsb pdb:3E6K|rcsb pdb:3E6V|rcsb pdb:3F80|rcsb pdb:3GMZ|rcsb pdb:3GN0|rcsb pdb:3KV2|rcsb pdb:3LP4|rcsb pdb:3LP7|rcsb pdb:3MFV|rcsb pdb:3MFW|rcsb pdb:3MJL|rcsb pdb:3SJT|rcsb pdb:3SKK|rcsb pdb:3TF3|rcsb pdb:3TH7|rcsb pdb:3THE|rcsb pdb:3THH|rcsb pdb:3THJ|rcsb pdb:4FCI|rcsb pdb:4FCK|rcsb pdb:4GSM|rcsb pdb:4GSV|rcsb pdb:4GSZ|rcsb pdb:4GWC|rcsb pdb:4GWD|rcsb pdb:4HWW|rcsb pdb:4HXQ|rcsb pdb:4IE1|rcsb pdb:6Q92|rcsb pdb:6Q9P|rcsb pdb:6QAF|rcsb pdb:6V7C|rcsb pdb:6V7D|rcsb pdb:6V7E|rcsb pdb:6V7F|reactome:R-HSA-6798695|reactome:R-HSA-70635|uniprotkb:P05089(identity)|entrezgene/locuslink:383(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:I5d1d/zT353OsLios95yEITNoWU9606 rogid:b8HHscDekWZdN1S4OxFTA6rjvn89606 intact-crc:8C5CF596752666A6|rigid:5cazm7lp0VJyNlB2E2uCjthIBs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61244 uniprotkb:Q969R5 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833645|imex:IM-21659-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750|uniprotkb:P61244(identity)|entrezgene/locuslink:4149(identity)|ddbj/embl/genbank:BC036092(identity) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750|uniprotkb:Q969R5(identity)|entrezgene/locuslink:83746(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:I5d1d/zT353OsLios95yEITNoWU9606 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 intact-crc:8C5CF596752666A6|rigid:5cazm7lp0VJyNlB2E2uCjthIBs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61244 uniprotkb:Q14582 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 intact:EBI-3943670|uniprotkb:A2A335|uniprotkb:Q5TZX4|ensembl:ENSP00000337889 psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:mad4_human(display_long)|uniprotkb:MXD4(gene name)|psi-mi:MXD4(display_short)|uniprotkb:BHLHC12(gene name synonym)|uniprotkb:MAD4(gene name synonym)|uniprotkb:Class C basic helix-loop-helix protein 12(gene name synonym)|uniprotkb:Max-associated protein 4(gene name synonym)|uniprotkb:Max-interacting transcriptional repressor MAD4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833645|imex:IM-21659-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750|uniprotkb:P61244(identity)|entrezgene/locuslink:4149(identity)|ddbj/embl/genbank:BC036092(identity) refseq:NP_006445.1|ensembl:ENSG00000123933(gene)|ensembl:ENST00000337190(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|reactome:R-HSA-1251985|uniprotkb:Q14582(identity)|entrezgene/locuslink:10608(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:I5d1d/zT353OsLios95yEITNoWU9606 rogid:PW+BZVOKcPTcyqqcnmhzX+/vTmk9606 intact-crc:8C5CF596752666A6|rigid:5cazm7lp0VJyNlB2E2uCjthIBs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61244 uniprotkb:Q13185 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833645|imex:IM-21659-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750|uniprotkb:P61244(identity)|entrezgene/locuslink:4149(identity)|ddbj/embl/genbank:BC036092(identity) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:I5d1d/zT353OsLios95yEITNoWU9606 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 intact-crc:8C5CF596752666A6|rigid:5cazm7lp0VJyNlB2E2uCjthIBs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61244 uniprotkb:Q9BW11 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 intact:EBI-741574|uniprotkb:Q53HK1|uniprotkb:Q7Z4Y0|uniprotkb:Q8NDJ7|uniprotkb:Q96ME3|uniprotkb:B4E0J1|ensembl:ENSP00000401867|ensembl:ENSP00000421463 psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:mad3_human(display_long)|uniprotkb:Max-associated protein 3(gene name synonym)|uniprotkb:BHLHC13(gene name synonym)|uniprotkb:Myx(gene name synonym)|uniprotkb:MXD3(gene name)|psi-mi:MXD3(display_short)|uniprotkb:MAD3(gene name synonym)|uniprotkb:Max-interacting transcriptional repressor MAD3(gene name synonym)|uniprotkb:Class C basic helix-loop-helix protein 13(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833645|imex:IM-21659-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750|uniprotkb:P61244(identity)|entrezgene/locuslink:4149(identity)|ddbj/embl/genbank:BC036092(identity) refseq:NP_001136407.1|refseq:NP_112590.1|ensembl:ENSG00000213347(gene)|ensembl:ENST00000439742(transcript)|ensembl:ENST00000513063(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|uniprotkb:Q9BW11(identity)|entrezgene/locuslink:83463(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:I5d1d/zT353OsLios95yEITNoWU9606 rogid:S2swfiFZ/PrU7X0TvjvvX9OJq809606 intact-crc:8C5CF596752666A6|rigid:5cazm7lp0VJyNlB2E2uCjthIBs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61244 uniprotkb:P63208 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833645|imex:IM-21659-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750|uniprotkb:P61244(identity)|entrezgene/locuslink:4149(identity)|ddbj/embl/genbank:BC036092(identity) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|entrezgene/locuslink:6500(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:I5d1d/zT353OsLios95yEITNoWU9606 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 intact-crc:8C5CF596752666A6|rigid:5cazm7lp0VJyNlB2E2uCjthIBs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61244 uniprotkb:P12524 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 intact:EBI-8833648|uniprotkb:A2A2C9|uniprotkb:Q9NUE9|uniprotkb:Q5QPL1|uniprotkb:Q14897|uniprotkb:Q5QPL0|uniprotkb:B4DJH2|ensembl:ENSP00000361903 psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:mycl_human(display_long)|uniprotkb:MYCL(gene name)|psi-mi:MYCL(display_short)|uniprotkb:BHLHE38(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 38(gene name synonym)|uniprotkb:LMYC(gene name synonym)|uniprotkb:MYCL1(gene name synonym)|uniprotkb:Protein L-Myc-1(gene name synonym)|uniprotkb:V-myc myelocytomatosis viral oncogene homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833645|imex:IM-21659-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750|uniprotkb:P61244(identity)|entrezgene/locuslink:4149(identity)|ddbj/embl/genbank:BC036092(identity) refseq:NP_001028253.1|refseq:NP_005367.2|refseq:NP_001028254.2|ensembl:ENSG00000116990(gene)|ensembl:ENST00000372816(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045607"(regulation of inner ear auditory receptor cell differentiation)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR002418(Transcription regulator Myc)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR012682(Transcription regulator Myc, N-terminal)|interpro:IPR036638|uniprotkb:P12524(identity)|entrezgene/locuslink:4610(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:I5d1d/zT353OsLios95yEITNoWU9606 rogid:ePS3eLYQL9wxUMrIJCPkEOyFU749606 intact-crc:8C5CF596752666A6|rigid:5cazm7lp0VJyNlB2E2uCjthIBs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61244 uniprotkb:Q8IY57 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833645|imex:IM-21659-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750|uniprotkb:P61244(identity)|entrezgene/locuslink:4149(identity)|ddbj/embl/genbank:BC036092(identity) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|entrezgene/locuslink:10138(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:I5d1d/zT353OsLios95yEITNoWU9606 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 intact-crc:8C5CF596752666A6|rigid:5cazm7lp0VJyNlB2E2uCjthIBs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61244 uniprotkb:P50539 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 intact:EBI-752241|uniprotkb:B1ANN7|uniprotkb:D3DR25|uniprotkb:D3DRA9|uniprotkb:Q15887|uniprotkb:Q6FHW2|uniprotkb:Q96E53|intact:EBI-28985206|ensembl:ENSP00000239007 psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:mxi1_human(display_long)|uniprotkb:MXI1(gene name)|psi-mi:MXI1(display_short)|uniprotkb:BHLHC11(gene name synonym)|uniprotkb:Class C basic helix-loop-helix protein 11(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833645|imex:IM-21659-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750|uniprotkb:P61244(identity)|entrezgene/locuslink:4149(identity)|ddbj/embl/genbank:BC036092(identity) refseq:NP_001008541.1|refseq:NP_005953.4|refseq:NP_569157.2|ensembl:ENSP00000239007|ensembl:ENST00000332674|ensembl:ENSP00000331152|ensembl:ENST00000361248|ensembl:ENST00000650810|ensembl:ENSP00000498390|ensembl:ENST00000650843|ensembl:ENSP00000498547|ensembl:ENST00000650900|ensembl:ENSP00000499209|ensembl:ENSP00000354606|ensembl:ENST00000369612|ensembl:ENSP00000358625|ensembl:ENST00000650644|ensembl:ENSP00000498900|ensembl:ENST00000650696|ensembl:ENSP00000499158|ensembl:ENST00000650952|ensembl:ENSP00000499161|ensembl:ENST00000651004|ensembl:ENSP00000498396|ensembl:ENSP00000498764|ensembl:ENST00000651467|ensembl:ENSP00000499128|ensembl:ENST00000651495|ensembl:ENSP00000498536|ensembl:ENST00000651516|ensembl:ENSP00000498873|ensembl:ENST00000651613|ensembl:ENSP00000498554|ensembl:ENST00000651811|ensembl:ENSP00000498472|ensembl:ENST00000651848|ensembl:ENSP00000498238|ensembl:ENST00000651866|ensembl:ENSP00000498306|ensembl:ENST00000652028|ensembl:ENSP00000498928|ensembl:ENST00000652463|ensembl:ENSP00000499087|ensembl:ENST00000651167|ensembl:ENST00000652506|ensembl:ENSP00000498573|ensembl:ENST00000652604|ensembl:ENSP00000498971|dip:DIP-205N|ensembl:ENSG00000119950(gene)|ensembl:ENST00000239007(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|uniprotkb:P50539(identity)|entrezgene/locuslink:4601(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:I5d1d/zT353OsLios95yEITNoWU9606 rogid:wHLrUka8vjKLADBM8EOqspNa/cU9606 intact-crc:8C5CF596752666A6|rigid:5cazm7lp0VJyNlB2E2uCjthIBs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61244 uniprotkb:Q92769 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 intact:EBI-301821|uniprotkb:Q5SRI8|uniprotkb:Q5SZ86|uniprotkb:Q8NEH4|uniprotkb:B4DL58|ensembl:ENSP00000430432|uniprotkb:E1P561|uniprotkb:B3KRS5 psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:hdac2_human(display_long)|uniprotkb:HDAC2(gene name)|psi-mi:HDAC2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833645|imex:IM-21659-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750|uniprotkb:P61244(identity)|entrezgene/locuslink:4149(identity)|ddbj/embl/genbank:BC036092(identity) go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035094"(response to nicotine)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042220"(response to cocaine)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q92769|rcsb pdb:3MAX|rcsb pdb:4LXZ|rcsb pdb:4LY1|rcsb pdb:5IWG|rcsb pdb:5IX0|rcsb pdb:6G3O|rcsb pdb:6WBW|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000196591(gene)|ensembl:ENST00000519065(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|rcsb pdb:6WHN|rcsb pdb:6WHO|rcsb pdb:6WHQ|rcsb pdb:6WHZ|rcsb pdb:6WI3|rcsb pdb:6XDM|rcsb pdb:6XEB|rcsb pdb:6XEC|rcsb pdb:7KBG|rcsb pdb:7KBH|rcsb pdb:7LTG|rcsb pdb:7LTK|rcsb pdb:7LTL|reactome:R-HSA-193670|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9615017|reactome:R-HSA-9619665|reactome:R-HSA-9679191|reactome:R-HSA-983231|rcsb pdb:6WBZ|refseq:NP_001518.3|dip:DIP-24220N|refseq:XP_011534090.1|refseq:XP_016866288.1|uniprotkb:Q92769(identity)|entrezgene/locuslink:3066(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:I5d1d/zT353OsLios95yEITNoWU9606 rogid:K4PpGz9E9/TrQZsgvrJuc+uYCn89606 intact-crc:8C5CF596752666A6|rigid:5cazm7lp0VJyNlB2E2uCjthIBs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61244 uniprotkb:P01106 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 intact:EBI-447544|intact:EBI-1058440|uniprotkb:P01107|uniprotkb:Q14026|uniprotkb:A8WFE7|ensembl:ENSP00000367207|ensembl:ENSP00000499105 psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:myc_human(display_long)|uniprotkb:BHLHE39(gene name synonym)|uniprotkb:Transcription factor p64(gene name synonym)|uniprotkb:MYC(gene name)|psi-mi:MYC(display_short)|uniprotkb:Proto-oncogene c-Myc(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 39(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833645|imex:IM-21659-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750|uniprotkb:P61244(identity)|entrezgene/locuslink:4149(identity)|ddbj/embl/genbank:BC036092(identity) refseq:NP_002458.2|dip:DIP-28143N|ensembl:ENSG00000136997(gene)|ensembl:ENST00000377970(transcript)|ensembl:ENST00000652288(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035690"|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044346"(fibroblast apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045656"(negative regulation of monocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051276"(chromosome organization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070848"(response to growth factor)|go:"GO:0070888"(E-box binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090096"(positive regulation of metanephric cap mesenchymal cell proliferation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1904672"(regulation of somatic stem cell population maintenance)|go:"GO:1905643"(positive regulation of DNA methylation)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR002418(Transcription regulator Myc)|interpro:IPR003327(Leucine zipper, Myc)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR012682(Transcription regulator Myc, N-terminal)|interpro:IPR036638|mint:P01106|rcsb pdb:1A93|rcsb pdb:1EE4|rcsb pdb:1MV0|rcsb pdb:1NKP|rcsb pdb:2A93|rcsb pdb:2OR9|rcsb pdb:4Y7R|rcsb pdb:5I4Z|rcsb pdb:5I50|rcsb pdb:6C4U|rcsb pdb:6E16|rcsb pdb:6E24|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015671"(oxygen transport)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0032986"(protein-DNA complex disassembly)|go:"GO:0032991"(protein-containing complex)|reactome:R-HSA-2122947|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-4411364|reactome:R-HSA-5687128|reactome:R-HSA-5689880|reactome:R-HSA-6785807|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8866911|reactome:R-HSA-8951430|reactome:R-HSA-9018519|reactome:R-HSA-9616222|uniprotkb:P01106(identity)|entrezgene/locuslink:4609(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:I5d1d/zT353OsLios95yEITNoWU9606 rogid:CCk+p9FN7JV6cTmJDlin2hRp1tg9606 intact-crc:8C5CF596752666A6|rigid:5cazm7lp0VJyNlB2E2uCjthIBs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15294 uniprotkb:Q92560 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 intact:EBI-1791447|uniprotkb:Q6LEM0|uniprotkb:Q7Z5E8|uniprotkb:A8K993|intact:EBI-2558090|ensembl:ENSP00000417132 psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:bap1_human(display_long)|uniprotkb:BAP1(gene name)|psi-mi:BAP1(display_short)|uniprotkb:KIAA0272(gene name synonym)|uniprotkb:hucep-6(orf name)|uniprotkb:BRCA1-associated protein 1(gene name synonym)|uniprotkb:Cerebral protein 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833802|imex:IM-21659-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N|uniprotkb:O15294(identity)|entrezgene/locuslink:8473(identity)|ddbj/embl/genbank:BC014434(identity) dip:DIP-47004N|refseq:NP_004647.1|ensembl:ENSG00000163930(gene)|ensembl:ENST00000460680(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003682"(chromatin binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061519"(macrophage homeostasis)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q92560|reactome:R-HSA-5689603|reactome:R-HSA-5693565|uniprotkb:Q92560(identity)|entrezgene/locuslink:8314(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 rogid:GMWdT1u5HUl29N+YgC/bCKTbxm49606 intact-crc:63F534F755729516|rigid://ozfeNRbx8c48nLzYo1eLW3RLw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15294 uniprotkb:Q8WXF1 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 intact:EBI-1392258|uniprotkb:Q5JTQ3|uniprotkb:Q8NCZ9|uniprotkb:Q8WXE8|uniprotkb:Q9NV36|ensembl:ENSP00000343966|ensembl:ENSP00000481916 psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:pspc1_human(display_long)|uniprotkb:PSPC1(gene name)|psi-mi:PSPC1(display_short)|uniprotkb:PSP1(gene name synonym)|uniprotkb:Paraspeckle protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833802|imex:IM-21659-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N|uniprotkb:O15294(identity)|entrezgene/locuslink:8473(identity)|ddbj/embl/genbank:BC014434(identity) refseq:XP_006719907.1|refseq:NP_001035879.1|dip:DIP-39028N|refseq:XP_016876139.1|ensembl:ENSG00000121390(gene)|ensembl:ENST00000338910(transcript)|ensembl:ENST00000619300(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034522|interpro:IPR034523|interpro:IPR035979|mint:Q8WXF1|rcsb pdb:3SDE|rcsb pdb:5IFN|rcsb pdb:5WPA|uniprotkb:Q8WXF1(identity)|entrezgene/locuslink:55269(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 rogid:voQ5zJMl7FYato9iDkUYfzZ3q/k9606 intact-crc:63F534F755729516|rigid://ozfeNRbx8c48nLzYo1eLW3RLw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15294 uniprotkb:P61964 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833802|imex:IM-21659-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N|uniprotkb:O15294(identity)|entrezgene/locuslink:8473(identity)|ddbj/embl/genbank:BC014434(identity) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|entrezgene/locuslink:11091(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 intact-crc:63F534F755729516|rigid://ozfeNRbx8c48nLzYo1eLW3RLw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15294 uniprotkb:O60502 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 intact:EBI-715814|uniprotkb:O75166|uniprotkb:Q86WV0|uniprotkb:Q8IV98|uniprotkb:Q9BVA5|uniprotkb:Q9HAR0|uniprotkb:B7WPB9|uniprotkb:D3DR79|uniprotkb:E9PGF9|ensembl:ENSP00000354850 psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:oga_human(display_long)|uniprotkb:OGA(gene name)|psi-mi:OGA(display_short)|uniprotkb:Beta-N-acetylglucosaminidase(gene name synonym)|uniprotkb:Beta-N-acetylhexosaminidase(gene name synonym)|uniprotkb:Beta-hexosaminidase(gene name synonym)|uniprotkb:HEXC(gene name synonym)|uniprotkb:KIAA0679(gene name synonym)|uniprotkb:MEA5(gene name synonym)|uniprotkb:MGEA5(gene name synonym)|uniprotkb:Meningioma-expressed antigen 5(gene name synonym)|uniprotkb:N-acetyl-beta-D-glucosaminidase(gene name synonym)|uniprotkb:N-acetyl-beta-glucosaminidase(gene name synonym)|uniprotkb:Nuclear cytoplasmic O-GlcNAcase and acetyltransferase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833802|imex:IM-21659-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N|uniprotkb:O15294(identity)|entrezgene/locuslink:8473(identity)|ddbj/embl/genbank:BC014434(identity) refseq:NP_001135906.1|refseq:NP_036347.1|ensembl:ENSG00000198408(gene)|ensembl:ENST00000361464(transcript)|go:"GO:0004415"(hyalurononglucosaminidase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006044"(N-acetylglucosamine metabolic process)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006517"(protein deglycosylation)|go:"GO:0009100"(glycoprotein metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016231"(beta-N-acetylglucosaminidase activity)|go:"GO:0102166"("[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity")|go:"GO:0102167"("[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity")|go:"GO:0102571"("[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity")|interpro:IPR011496(Hyaluronidase eukaryotic/prokaryotic)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|rcsb pdb:2YDQ|rcsb pdb:5M7R|rcsb pdb:5M7S|rcsb pdb:5M7T|rcsb pdb:5M7U|rcsb pdb:5TKE|rcsb pdb:5UHK|rcsb pdb:5UHL|rcsb pdb:5UHO|rcsb pdb:5UHP|rcsb pdb:5UN8|rcsb pdb:5UN9|rcsb pdb:5VVO|rcsb pdb:5VVT|rcsb pdb:5VVU|rcsb pdb:5VVV|rcsb pdb:5VVX|rcsb pdb:6HKI|rcsb pdb:6PM9|go:"GO:0005634"(nucleus)|uniprotkb:O60502(identity)|entrezgene/locuslink:10724(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 rogid:KEvP6+2BWwsxrs8hsIjQhKAQGVo9606 intact-crc:63F534F755729516|rigid://ozfeNRbx8c48nLzYo1eLW3RLw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15294 uniprotkb:A6NHR9 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 intact:EBI-2801919|uniprotkb:O75141|uniprotkb:Q6AHX6|uniprotkb:Q9H6Q2|uniprotkb:Q6ZTQ8|intact:EBI-3192385|uniprotkb:Q9UG39|ensembl:ENSP00000326603 psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:smhd1_human(display_long)|uniprotkb:KIAA0650(gene name synonym)|uniprotkb:SMCHD1(gene name)|psi-mi:SMCHD1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833802|imex:IM-21659-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N|uniprotkb:O15294(identity)|entrezgene/locuslink:8473(identity)|ddbj/embl/genbank:BC014434(identity) refseq:NP_056110.2|ensembl:ENSG00000101596(gene)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR036277|interpro:IPR036890|interpro:IPR038892|mint:A6NHR9|rcsb pdb:6MW7|ensembl:ENST00000320876(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006302"(double-strand break repair)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043584"(nose development)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0060820"(inactivation of X chromosome by heterochromatin assembly)|go:"GO:0060821"(obsolete inactivation of X chromosome by DNA methylation)|uniprotkb:A6NHR9(identity)|entrezgene/locuslink:23347(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 rogid:7tHwsz7p8pAqG9grnerpgMTmt3Q9606 intact-crc:63F534F755729516|rigid://ozfeNRbx8c48nLzYo1eLW3RLw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15294 uniprotkb:Q9BTC0 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 intact:EBI-739985|uniprotkb:O15043|uniprotkb:A8MY65|uniprotkb:Q3ZTL7|uniprotkb:Q3ZTL8|uniprotkb:Q4VXS1|uniprotkb:Q4VXS2|uniprotkb:Q4VXV8|uniprotkb:Q96D72|uniprotkb:Q9BQW0|uniprotkb:Q9BW03|uniprotkb:Q9H4G6|uniprotkb:Q9H4G7|uniprotkb:Q9NTU8|uniprotkb:Q9NUM8|uniprotkb:Q9UFB6|uniprotkb:B9EH82|uniprotkb:Q4VXV9|uniprotkb:E1P5I1|intact:EBI-28975591|ensembl:ENSP00000266070|ensembl:ENSP00000378752 psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:dido1_human(display_long)|uniprotkb:DIDO1(gene name)|psi-mi:DIDO1(display_short)|uniprotkb:Death-associated transcription factor 1(gene name synonym)|uniprotkb:C20orf158(gene name synonym)|uniprotkb:DATF1(gene name synonym)|uniprotkb:KIAA0333(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833802|imex:IM-21659-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N|uniprotkb:O15294(identity)|entrezgene/locuslink:8473(identity)|ddbj/embl/genbank:BC014434(identity) ensembl:ENSP00000266070|ensembl:ENST00000354665|ensembl:ENSP00000346692|ensembl:ENST00000370366|ensembl:ENSP00000359391|ensembl:ENST00000370368|ensembl:ENSP00000359394|ensembl:ENST00000370371|ensembl:ENSP00000359397|ensembl:ENST00000395340|ensembl:ENSP00000378749|ensembl:ENSP00000378752|refseq:NP_001180298.1|refseq:NP_001180299.1|refseq:NP_071388.2|refseq:NP_149072.2|refseq:NP_542986.1|refseq:NP_542987.2|ensembl:ENSG00000101191(gene)|ensembl:ENST00000266070(transcript)|ensembl:ENST00000395343(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0097190"(apoptotic signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003618(Transcription elongation factor S-II, central region)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012921(Spen paralogue and orthologue C-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR033082|interpro:IPR036575|mint:Q9BTC0|rcsb pdb:2M3H|rcsb pdb:4L7X|reactome:R-HSA-1221632|refseq:XP_011526811.1|uniprotkb:Q9BTC0(identity)|entrezgene/locuslink:11083(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 rogid:xtp4cq/633PxqppXYlVvameuI7M9606 intact-crc:63F534F755729516|rigid://ozfeNRbx8c48nLzYo1eLW3RLw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15294 uniprotkb:Q9P035 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 intact:EBI-359013|intact:EBI-1049123|uniprotkb:A0PJA1|uniprotkb:Q280Z3|uniprotkb:Q6PD63|uniprotkb:Q8IUI5|uniprotkb:Q8NC86|uniprotkb:Q8NCB1|uniprotkb:Q96T12|uniprotkb:Q9NQA7|uniprotkb:B4DRF4|intact:EBI-28973764|ensembl:ENSP00000261875 psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:hacd3_human(display_long)|uniprotkb:Butyrate-induced protein 1(gene name synonym)|uniprotkb:PTPLAD1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase-like A domain-containing protein 1(gene name synonym)|uniprotkb:HACD3(gene name)|psi-mi:HACD3(display_short)|uniprotkb:3-hydroxyacyl-CoA dehydratase 3(gene name synonym)|uniprotkb:BIND1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833802|imex:IM-21659-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N|uniprotkb:O15294(identity)|entrezgene/locuslink:8473(identity)|ddbj/embl/genbank:BC014434(identity) ensembl:ENSP00000261875|ensembl:ENST00000442729|ensembl:ENSP00000392491|refseq:NP_057479.2|ensembl:ENSG00000074696(gene)|ensembl:ENST00000261875(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005925"(focal adhesion)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0018812"(3-hydroxyacyl-CoA dehydratase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030497"(fatty acid elongation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0102158"(very-long-chain 3-hydroxyacyl-CoA dehydratase activity)|go:"GO:0102343"(3-hydroxy-arachidoyl-CoA dehydratase activity)|go:"GO:0102344"(3-hydroxy-behenoyl-CoA dehydratase activity)|go:"GO:0102345"(3-hydroxy-lignoceroyl-CoA dehydratase activity)|interpro:IPR007052(CS domain)|interpro:IPR007482(Protein-tyrosine phosphatase-like, PTPLA)|interpro:IPR008978(HSP20-like chaperone)|mint:Q9P035|reactome:R-HSA-75876|uniprotkb:Q9P035(identity)|entrezgene/locuslink:51495(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 rogid:U31K6H8I2f5j7FRhfHiY0cG4smA9606 intact-crc:63F534F755729516|rigid://ozfeNRbx8c48nLzYo1eLW3RLw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15294 uniprotkb:Q9UBL3 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|ensembl:ENSP00000340896|uniprotkb:A8K7C3|uniprotkb:D3DSW9 psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833802|imex:IM-21659-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N|uniprotkb:O15294(identity)|entrezgene/locuslink:8473(identity)|ddbj/embl/genbank:BC014434(identity) refseq:NP_001098684.1|refseq:NP_004665.2|ensembl:ENSG00000129691(gene)|ensembl:ENST00000343823(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|rcsb pdb:4X8N|refseq:NP_001248761.1|dip:DIP-29222N|uniprotkb:Q9UBL3(identity)|entrezgene/locuslink:9070(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606 intact-crc:63F534F755729516|rigid://ozfeNRbx8c48nLzYo1eLW3RLw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15294 uniprotkb:Q9UPV9 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 intact:EBI-1105048|ensembl:ENSP00000328998|uniprotkb:Q96B69|uniprotkb:Q63HR0|uniprotkb:E9PDS2|uniprotkb:Q659B5|uniprotkb:J3KNT7 psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:trak1_human(display_long)|uniprotkb:Protein Milton(gene name synonym)|uniprotkb:TRAK1(gene name)|psi-mi:TRAK1(display_short)|uniprotkb:KIAA1042(gene name synonym)|uniprotkb:OIP106(gene name synonym)|uniprotkb:106 kDa O-GlcNAc transferase-interacting protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833802|imex:IM-21659-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N|uniprotkb:O15294(identity)|entrezgene/locuslink:8473(identity)|ddbj/embl/genbank:BC014434(identity) ensembl:ENSG00000182606(gene)|ensembl:ENST00000327628(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006605"(protein targeting)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0017022"(myosin binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044295"(axonal growth cone)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048311"(mitochondrion distribution)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006933(HAP1, N-terminal)|interpro:IPR022154|mint:Q9UPV9|reactome:R-HSA-6802952|reactome:R-HSA-9013419|reactome:R-HSA-9013425|go:"GO:0030425"(dendrite)|refseq:NP_001252537.1|refseq:NP_055780.2|refseq:NP_001252539.1|refseq:NP_001036111.1|uniprotkb:Q9UPV9(identity)|entrezgene/locuslink:22906(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 rogid:wO1gttlJMJ/4RvsellzkZ2YHGiE9606 intact-crc:63F534F755729516|rigid://ozfeNRbx8c48nLzYo1eLW3RLw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15294 uniprotkb:P01040 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 intact:EBI-724303|ensembl:ENSP00000264474|uniprotkb:Q6IB90 psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:cyta_human(display_long)|uniprotkb:Cystatin-AS(gene name synonym)|uniprotkb:Stefin-A(gene name synonym)|uniprotkb:CSTA(gene name)|psi-mi:CSTA(display_short)|uniprotkb:STF1(gene name synonym)|uniprotkb:STFA(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833802|imex:IM-21659-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N|uniprotkb:O15294(identity)|entrezgene/locuslink:8473(identity)|ddbj/embl/genbank:BC014434(identity) refseq:NP_005204.1|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR001713(Proteinase inhibitor I25A, stefin A)|mint:P01040|rcsb pdb:1CYU|rcsb pdb:1CYV|rcsb pdb:1DVC|rcsb pdb:1DVD|rcsb pdb:1GD3|rcsb pdb:1GD4|rcsb pdb:1N9J|rcsb pdb:1NB3|rcsb pdb:1NB5|rcsb pdb:3K9M|rcsb pdb:3KFQ|interpro:IPR018073|rcsb pdb:3KSE|reactome:R-HSA-6809371|ensembl:ENSG00000121552(gene)|ensembl:ENST00000264474(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002020"(protease binding)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0045861"(negative regulation of proteolysis)|uniprotkb:P01040(identity)|entrezgene/locuslink:1475(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 rogid:SzbpyWUHlOtItIvffzuwhcqFsDI9606 intact-crc:63F534F755729516|rigid://ozfeNRbx8c48nLzYo1eLW3RLw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15294 uniprotkb:P49368 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688 psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833802|imex:IM-21659-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N|uniprotkb:O15294(identity)|entrezgene/locuslink:8473(identity)|ddbj/embl/genbank:BC014434(identity) refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N|uniprotkb:P49368(identity)|entrezgene/locuslink:7203(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606 intact-crc:63F534F755729516|rigid://ozfeNRbx8c48nLzYo1eLW3RLw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15294 uniprotkb:Q9H9L4 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 intact:EBI-2560840|uniprotkb:Q8N3B5|uniprotkb:Q9NX51|uniprotkb:Q96CV0|ensembl:ENSP00000415436 psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:kanl2_human(display_long)|uniprotkb:KANSL2(gene name)|psi-mi:KANSL2(display_short)|uniprotkb:C12orf41(gene name synonym)|uniprotkb:NSL complex protein NSL2(gene name synonym)|uniprotkb:NSL2(gene name synonym)|uniprotkb:Non-specific lethal 2 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833802|imex:IM-21659-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N|uniprotkb:O15294(identity)|entrezgene/locuslink:8473(identity)|ddbj/embl/genbank:BC014434(identity) refseq:NP_060292.3|ensembl:ENSG00000139620(gene)|ensembl:ENST00000420613(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044545"(NSL complex)|interpro:IPR025927|interpro:IPR026316|mint:Q9H9L4|rcsb pdb:4CY2|reactome:R-HSA-3214847|uniprotkb:Q9H9L4(identity)|entrezgene/locuslink:54934(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 rogid:ymOXqnaeH6HuGcHPg4R2XVmWAz89606 intact-crc:63F534F755729516|rigid://ozfeNRbx8c48nLzYo1eLW3RLw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15294 uniprotkb:Q9HBD1 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 intact:EBI-2340719|uniprotkb:Q8N3D6|uniprotkb:Q9H5J2|uniprotkb:Q9NWN9|uniprotkb:Q9NXE1|uniprotkb:Q86ST6|uniprotkb:Q5JPD7|uniprotkb:Q9HBD2|uniprotkb:Q96F27|uniprotkb:Q4VXB1|ensembl:ENSP00000349783|ensembl:ENSP00000362774 psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:rc3h2_human(display_long)|uniprotkb:RC3H2(gene name)|psi-mi:RC3H2(display_short)|uniprotkb:MNAB(gene name synonym)|uniprotkb:RNF164(gene name synonym)|uniprotkb:Membrane-associated nucleic acid-binding protein(gene name synonym)|uniprotkb:RING finger protein 164(gene name synonym)|uniprotkb:RING finger and CCCH-type zinc finger domain-containing protein 2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Roquin-2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833802|imex:IM-21659-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N|uniprotkb:O15294(identity)|entrezgene/locuslink:8473(identity)|ddbj/embl/genbank:BC014434(identity) refseq:NP_001094058.1|refseq:NP_061323.2|ensembl:ENSG00000056586(gene)|ensembl:ENST00000357244(transcript)|ensembl:ENST00000373670(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009986"(cell surface)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0042098"(T cell proliferation)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0046872"(metal ion binding)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0060173"(limb development)|go:"GO:0061470"(T follicular helper cell differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000628"(regulation of miRNA metabolic process)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|interpro:IPR032670|interpro:IPR036855|interpro:IPR041523|rcsb pdb:4Z30|rcsb pdb:4Z31|rcsb pdb:4ZLC|rcsb pdb:4ZLD|uniprotkb:Q9HBD1(identity)|entrezgene/locuslink:54542(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 rogid:UThBG9DsQJ7jfnx9xkCBkBKkaT89606 intact-crc:63F534F755729516|rigid://ozfeNRbx8c48nLzYo1eLW3RLw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15294 uniprotkb:Q7Z3B3 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 intact:EBI-740244|uniprotkb:Q6AW85|uniprotkb:Q8IYH1|uniprotkb:Q9BRH0|uniprotkb:Q9NTE7|uniprotkb:Q9UFT0|uniprotkb:Q9ULF3|uniprotkb:A8K5E4|ensembl:ENSP00000262419|ensembl:ENSP00000387393|ensembl:ENSP00000461484|ensembl:ENSP00000461812|intact:EBI-10178305|uniprotkb:B3KT49|uniprotkb:I3L4J3 psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:kanl1_human(display_long)|uniprotkb:KANSL1(gene name)|psi-mi:KANSL1(display_short)|uniprotkb:KIAA1267(gene name synonym)|uniprotkb:MLL1/MLL complex subunit KANSL1(gene name synonym)|uniprotkb:MSL1 homolog 1(gene name synonym)|uniprotkb:MSL1V1(gene name synonym)|uniprotkb:NSL complex protein NSL1(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Non-specific lethal 1 homolog(gene name synonym)|uniprotkb:CENP-36(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833802|imex:IM-21659-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N|uniprotkb:O15294(identity)|entrezgene/locuslink:8473(identity)|ddbj/embl/genbank:BC014434(identity) refseq:NP_001180394.1|refseq:NP_001180395.1|refseq:NP_056258.1|refseq:XP_006721886.1|ensembl:ENSG00000120071(gene)|ensembl:ENST00000262419(transcript)|ensembl:ENST00000432791(transcript)|ensembl:ENST00000572904(transcript)|ensembl:ENST00000574590(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0071339"(MLL1 complex)|interpro:IPR026180|interpro:IPR029332|mint:Q7Z3B3|rcsb pdb:4CY1|rcsb pdb:4CY2|reactome:R-HSA-3214847|refseq:XP_006721887.1|uniprotkb:Q7Z3B3(identity)|entrezgene/locuslink:284058(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 rogid:Co/MKm4PZcwn3BUf6ZKYOqW0VhA9606 intact-crc:63F534F755729516|rigid://ozfeNRbx8c48nLzYo1eLW3RLw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15294 uniprotkb:Q9P0U4 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 intact:EBI-949911|ensembl:ENSP00000285106|uniprotkb:Q8N2W4|uniprotkb:Q96BC8|uniprotkb:Q9P2V7|uniprotkb:B2RC03 psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:cxxc1_human(display_long)|uniprotkb:CFP1(gene name synonym)|uniprotkb:PHD finger and CXXC domain-containing protein 1(gene name synonym)|uniprotkb:CXXC1(gene name)|psi-mi:CXXC1(display_short)|uniprotkb:CGBP(gene name synonym)|uniprotkb:PCCX1(gene name synonym)|uniprotkb:PHF18(gene name synonym)|uniprotkb:CpG-binding protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833802|imex:IM-21659-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N|uniprotkb:O15294(identity)|entrezgene/locuslink:8473(identity)|ddbj/embl/genbank:BC014434(identity) ensembl:ENSG00000154832(gene)|ensembl:ENST00000285106(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|reactome:R-HSA-381038|interpro:IPR022056|interpro:IPR037869|mint:Q9P0U4|rcsb pdb:3QMB|rcsb pdb:3QMC|rcsb pdb:3QMD|rcsb pdb:3QMG|rcsb pdb:3QMH|rcsb pdb:3QMI|refseq:NP_001095124.1|refseq:NP_055408.2|refseq:XP_011524242.1|refseq:XP_016881207.1|dip:DIP-50001N|uniprotkb:Q9P0U4(identity)|entrezgene/locuslink:30827(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 rogid:nWwPX7OlafdCMD8Qg+hETjNkKgY9606 intact-crc:63F534F755729516|rigid://ozfeNRbx8c48nLzYo1eLW3RLw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15294 uniprotkb:Q8NFU7 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 intact:EBI-8833805|uniprotkb:Q5VUP7|uniprotkb:Q9C0I7|uniprotkb:Q8TCR1|uniprotkb:Q7Z6B6|ensembl:ENSP00000362748 psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:tet1_human(display_long)|uniprotkb:CXXC-type zinc finger protein 6(gene name synonym)|uniprotkb:CXXC6(gene name synonym)|uniprotkb:KIAA1676(gene name synonym)|uniprotkb:LCX(gene name synonym)|uniprotkb:Leukemia-associated protein with a CXXC domain(gene name synonym)|uniprotkb:Ten-eleven translocation 1 gene protein(gene name synonym)|uniprotkb:TET1(gene name)|psi-mi:TET1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833802|imex:IM-21659-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N|uniprotkb:O15294(identity)|entrezgene/locuslink:8473(identity)|ddbj/embl/genbank:BC014434(identity) ensembl:ENSP00000362748|refseq:NP_085128.2|ensembl:ENSG00000138336(gene)|ensembl:ENST00000373644(transcript)|go:"GO:0001826"(inner cell mass cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0006211"(5-methylcytosine catabolic process)|go:"GO:0006325"(chromatin organization)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070579"(methylcytosine dioxygenase activity)|go:"GO:0070989"(oxidative demethylation)|go:"GO:0080111"(DNA demethylation)|go:"GO:0090310"(negative regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR024779|interpro:IPR040175|rcsb pdb:6ASD|reactome:R-HSA-5221030|uniprotkb:Q8NFU7(identity)|entrezgene/locuslink:80312(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 rogid:xse96yfEnUcHM/m+UWF+9O51co49606 intact-crc:63F534F755729516|rigid://ozfeNRbx8c48nLzYo1eLW3RLw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15294 uniprotkb:Q9BQE3 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833802|imex:IM-21659-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N|uniprotkb:O15294(identity)|entrezgene/locuslink:8473(identity)|ddbj/embl/genbank:BC014434(identity) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1|uniprotkb:Q9BQE3(identity)|entrezgene/locuslink:84790(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:63F534F755729516|rigid://ozfeNRbx8c48nLzYo1eLW3RLw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15294 uniprotkb:Q9P0W8 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 intact:EBI-6152737|uniprotkb:Q5BKY5|uniprotkb:Q9P0W7|uniprotkb:Q96HF3|uniprotkb:Q8WX30|uniprotkb:Q9H0X0|ensembl:ENSP00000377176 psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:spat7_human(display_long)|uniprotkb:HSD-3.1(gene name synonym)|uniprotkb:HSD3(gene name synonym)|uniprotkb:Spermatogenesis-associated protein HSD3(gene name synonym)|uniprotkb:SPATA7(gene name)|psi-mi:SPATA7(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833802|imex:IM-21659-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N|uniprotkb:O15294(identity)|entrezgene/locuslink:8473(identity)|ddbj/embl/genbank:BC014434(identity) refseq:NP_001035518.1|refseq:NP_060888.2|ensembl:ENSG00000042317(gene)|ensembl:ENST00000393545(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050896"(response to stimulus)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903546"(protein localization to photoreceptor outer segment)|go:"GO:1903621"(protein localization to photoreceptor connecting cilium)|interpro:IPR029357|mint:Q9P0W8|uniprotkb:Q9P0W8(identity)|entrezgene/locuslink:55812(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 rogid:g+djqWT3cKjfCPnHVufeoKm9dYM9606 intact-crc:63F534F755729516|rigid://ozfeNRbx8c48nLzYo1eLW3RLw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15294 uniprotkb:Q86X55 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 intact:EBI-2339854|uniprotkb:A6NN38|ensembl:ENSP00000325690 psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:carm1_human(display_long)|uniprotkb:CARM1(gene name)|psi-mi:CARM1(display_short)|uniprotkb:PRMT4(gene name synonym)|uniprotkb:Protein arginine N-methyltransferase 4(gene name synonym)|uniprotkb:Coactivator-associated arginine methyltransferase 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833802|imex:IM-21659-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N|uniprotkb:O15294(identity)|entrezgene/locuslink:8473(identity)|ddbj/embl/genbank:BC014434(identity) refseq:NP_954592.1|refseq:XP_005259765.1|dip:DIP-44071N|ensembl:ENSG00000142453(gene)|ensembl:ENST00000327064(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007568"(aging)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034970"(histone H3-R2 methylation)|go:"GO:0034971"(histone H3-R17 methylation)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0035642"("histone methyltransferase activity (H3-R17 specific)")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:1902415"(regulation of mRNA binding)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020989|interpro:IPR025799|interpro:IPR029063|mint:Q86X55|rcsb pdb:2Y1W|rcsb pdb:2Y1X|rcsb pdb:4IKP|rcsb pdb:5DWQ|rcsb pdb:5DX0|rcsb pdb:5DX1|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5DXJ|rcsb pdb:5U4X|rcsb pdb:6ARJ|rcsb pdb:6ARV|rcsb pdb:6D2L|rcsb pdb:6DVR|rcsb pdb:6IZQ|rcsb pdb:6S70|rcsb pdb:6S71|rcsb pdb:6S74|rcsb pdb:6S77|rcsb pdb:6S79|rcsb pdb:6S7A|rcsb pdb:6S7B|rcsb pdb:6S7C|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-3214858|reactome:R-HSA-381340|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-6804114|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|go:"GO:0051591"(response to cAMP)|uniprotkb:Q86X55(identity)|entrezgene/locuslink:10498(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 rogid:1x1bUjqcA/ZpmrSsSM545ReYH2A9606 intact-crc:63F534F755729516|rigid://ozfeNRbx8c48nLzYo1eLW3RLw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15294 uniprotkb:Q04917 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 intact:EBI-306940|ensembl:ENSP00000248975|intact:EBI-11759595 psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:1433f_human(display_long)|uniprotkb:YWHAH(gene name)|psi-mi:YWHAH(display_short)|uniprotkb:YWHA1(gene name synonym)|uniprotkb:Protein AS1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833802|imex:IM-21659-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N|uniprotkb:O15294(identity)|entrezgene/locuslink:8473(identity)|ddbj/embl/genbank:BC014434(identity) go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:Q04917|rcsb pdb:2C63|rcsb pdb:2C74|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|ensembl:ENSG00000128245(gene)|ensembl:ENST00000248975(transcript)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0003779"(actin binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006713"(glucocorticoid catabolic process)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0014704"(intercalated disc)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_003396.1|dip:DIP-27566N|uniprotkb:Q04917(identity)|entrezgene/locuslink:7533(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 rogid:VhFYPSsW3IRC388FTlmwwN37HnU9606 intact-crc:63F534F755729516|rigid://ozfeNRbx8c48nLzYo1eLW3RLw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15294 uniprotkb:P51610 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 intact:EBI-396176|intact:EBI-2832627|uniprotkb:Q6P4G5|intact:EBI-12037257|intact:EBI-14324845|ensembl:ENSP00000309555|intact:EBI-12980473 psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:hcfc1_human(display_long)|uniprotkb:HCFC1(gene name)|psi-mi:HCFC1(display_short)|uniprotkb:HCF1(gene name synonym)|uniprotkb:C1 factor(gene name synonym)|uniprotkb:VP16 accessory protein(gene name synonym)|uniprotkb:VCAF(gene name synonym)|uniprotkb:CFF(gene name synonym)|uniprotkb:HFC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833802|imex:IM-21659-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N|uniprotkb:O15294(identity)|entrezgene/locuslink:8473(identity)|ddbj/embl/genbank:BC014434(identity) refseq:NP_005325.2|refseq:XP_006724879.1|rcsb pdb:6MA1|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|reactome:R-HSA-2151201|reactome:R-HSA-3214847|reactome:R-HSA-5689603|ensembl:ENSG00000172534(gene)|ensembl:ENST00000310441(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019046"(release from viral latency)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR036116|interpro:IPR037854|interpro:IPR043536|mint:P51610|rcsb pdb:4GO6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:5LWV|dip:DIP-32955N|uniprotkb:P51610(identity)|entrezgene/locuslink:3054(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 rogid:RzsCRe9l6md3DI87H4ZgdR9oBMI9606 intact-crc:63F534F755729516|rigid://ozfeNRbx8c48nLzYo1eLW3RLw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15294 uniprotkb:Q03164 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 intact:EBI-591370|ensembl:ENSP00000374157|uniprotkb:Q13743|uniprotkb:Q13744|uniprotkb:Q14845|uniprotkb:Q16364|uniprotkb:Q6UBD1|uniprotkb:Q9UMA3|intact:EBI-2614650|uniprotkb:Q59FF2|uniprotkb:Q9UD94|uniprotkb:E9PQG7|uniprotkb:Q9HBJ3 psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:kmt2a_human(display_long)|uniprotkb:KMT2A(gene name)|psi-mi:KMT2A(display_short)|uniprotkb:ALL-1(gene name synonym)|uniprotkb:ALL1(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 7(gene name synonym)|uniprotkb:CXXC7(gene name synonym)|uniprotkb:HRX(gene name synonym)|uniprotkb:HTRX(gene name synonym)|uniprotkb:MLL(gene name synonym)|uniprotkb:MLL1(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 1(gene name synonym)|uniprotkb:TRX1(gene name synonym)|uniprotkb:Trithorax-like protein(gene name synonym)|uniprotkb:Zinc finger protein HRX(gene name synonym)|uniprotkb:Cysteine methyltransferase KMT2A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833802|imex:IM-21659-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N|uniprotkb:O15294(identity)|entrezgene/locuslink:8473(identity)|ddbj/embl/genbank:BC014434(identity) go:"GO:2000615"(regulation of histone H3-K9 acetylation)|interpro:IPR001214(SET)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036427|interpro:IPR037927|interpro:IPR041958|interpro:IPR042023|interpro:IPR042025|interpro:IPR044133|mint:Q03164|rcsb pdb:2AGH|rcsb pdb:2J2S|rcsb pdb:2JYI|rcsb pdb:2KKF|rcsb pdb:2KU7|rcsb pdb:2KYU|rcsb pdb:2LXS|rcsb pdb:2LXT|rcsb pdb:2MSR|rcsb pdb:2MTN|rcsb pdb:2W5Y|ensembl:ENSG00000118058(gene)|ensembl:ENST00000389506(transcript)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071440"(regulation of histone H3-K14 acetylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|go:"GO:1905642"(negative regulation of DNA methylation)|refseq:NP_001184033.1|refseq:NP_005924.2|ensembl:ENSP00000374157|ensembl:ENST00000534358|ensembl:ENSP00000436786|ensembl:ENST00000649699|ensembl:ENSP00000496927|dip:DIP-29221N|rcsb pdb:2W5Z|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3LQH|rcsb pdb:3LQI|rcsb pdb:3LQJ|rcsb pdb:3P4F|rcsb pdb:3U85|rcsb pdb:3U88|rcsb pdb:4ESG|rcsb pdb:4GQ6|rcsb pdb:4NW3|rcsb pdb:5F5E|rcsb pdb:5F6L|rcsb pdb:5SVH|rcsb pdb:6EMQ|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U9K|rcsb pdb:6U9M|rcsb pdb:6U9N|rcsb pdb:6U9R|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|reactome:R-HSA-3214841|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9616222|uniprotkb:Q03164(identity)|entrezgene/locuslink:4297(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 rogid:r9J9pjnLZI7GCBSHYqnmzjv9WvM9606 intact-crc:63F534F755729516|rigid://ozfeNRbx8c48nLzYo1eLW3RLw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15294 uniprotkb:P31629 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 intact:EBI-2514157|ensembl:ENSP00000012134|ensembl:ENSP00000356575|ensembl:ENSP00000356576|uniprotkb:Q02646|uniprotkb:Q9NS05|uniprotkb:Q5THT5 psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:zep2_human(display_long)|uniprotkb:HIVEP2(gene name)|psi-mi:HIVEP2(display_short)|uniprotkb:Human immunodeficiency virus type I enhancer-binding protein 2(gene name synonym)|uniprotkb:MHC-binding protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833802|imex:IM-21659-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N|uniprotkb:O15294(identity)|entrezgene/locuslink:8473(identity)|ddbj/embl/genbank:BC014434(identity) ensembl:ENSG00000010818(gene)|ensembl:ENST00000012134(transcript)|ensembl:ENST00000367603(transcript)|ensembl:ENST00000367604(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:XP_016866294.1|refseq:NP_006725.3|uniprotkb:P31629(identity)|entrezgene/locuslink:3097(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 rogid:/QXXmthWJq/FkgWwIqkVb1z16EU9606 intact-crc:63F534F755729516|rigid://ozfeNRbx8c48nLzYo1eLW3RLw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15294 uniprotkb:P48643 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8 psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833802|imex:IM-21659-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N|uniprotkb:O15294(identity)|entrezgene/locuslink:8473(identity)|ddbj/embl/genbank:BC014434(identity) refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N|uniprotkb:P48643(identity)|entrezgene/locuslink:22948(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606 intact-crc:63F534F755729516|rigid://ozfeNRbx8c48nLzYo1eLW3RLw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15294 uniprotkb:Q9P2N6 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 intact:EBI-395317|uniprotkb:A1L184|uniprotkb:Q05BU4|uniprotkb:Q6P3X2|uniprotkb:Q6PJH6|uniprotkb:Q86T19|uniprotkb:Q9H0C9|uniprotkb:Q9H8C9|uniprotkb:Q9HAP8|uniprotkb:Q9NWE5|intact:EBI-2560782|intact:EBI-726977|uniprotkb:Q96L64|ensembl:ENSP00000499674|uniprotkb:D3DXH3|uniprotkb:D3DXH4 psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:kanl3_human(display_long)|uniprotkb:KANSL3(gene name)|psi-mi:KANSL3(display_short)|uniprotkb:KIAA1310(gene name synonym)|uniprotkb:NSL complex protein NSL3(gene name synonym)|uniprotkb:NSL3(gene name synonym)|uniprotkb:Non-specific lethal 3 homolog(gene name synonym)|uniprotkb:PRTD(gene name synonym)|uniprotkb:SI1(gene name synonym)|uniprotkb:Serum inhibited-related protein(gene name synonym)|uniprotkb:Testis development protein PRTD(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833802|imex:IM-21659-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N|uniprotkb:O15294(identity)|entrezgene/locuslink:8473(identity)|ddbj/embl/genbank:BC014434(identity) ensembl:ENSG00000114982(gene)|ensembl:ENST00000666923(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR026555|interpro:IPR029058|mint:Q9P2N6|reactome:R-HSA-3214847|refseq:NP_001108488.1|refseq:XP_005264041.1|uniprotkb:Q9P2N6(identity)|entrezgene/locuslink:55683(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 rogid:939a58MqNe7Tnr1HRhS7YpD6s6I9606 intact-crc:63F534F755729516|rigid://ozfeNRbx8c48nLzYo1eLW3RLw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15294 uniprotkb:Q15291 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 intact:EBI-592823|uniprotkb:A8K272|uniprotkb:Q7Z6D8|uniprotkb:Q8NDZ7|ensembl:ENSP00000264515 psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:rbbp5_human(display_long)|uniprotkb:Retinoblastoma-binding protein RBQ-3(gene name synonym)|uniprotkb:RBBP5(gene name)|psi-mi:RBBP5(display_short)|uniprotkb:RBQ3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833802|imex:IM-21659-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N|uniprotkb:O15294(identity)|entrezgene/locuslink:8473(identity)|ddbj/embl/genbank:BC014434(identity) refseq:NP_001180201.1|refseq:NP_001180202.1|refseq:NP_005048.2|dip:DIP-29224N|ensembl:ENSG00000117222(gene)|ensembl:ENST00000264515(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037850|mint:Q15291|rcsb pdb:3P4F|rcsb pdb:4X8N|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6KM7|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6PWX|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|uniprotkb:Q15291(identity)|entrezgene/locuslink:5929(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 rogid:Zl8yHcbL1C6StHPyD+875Ccy6gk9606 intact-crc:63F534F755729516|rigid://ozfeNRbx8c48nLzYo1eLW3RLw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15294 uniprotkb:P15822 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 intact:EBI-722264|uniprotkb:Q14122|uniprotkb:Q5VW60|uniprotkb:B2RTU3|uniprotkb:Q5MPB1|ensembl:ENSP00000368698 psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:zep1_human(display_long)|uniprotkb:Human immunodeficiency virus type I enhancer-binding protein 1(gene name synonym)|uniprotkb:Major histocompatibility complex-binding protein 1(gene name synonym)|uniprotkb:Positive regulatory domain II-binding factor 1(gene name synonym)|uniprotkb:HIVEP1(gene name)|psi-mi:HIVEP1(display_short)|uniprotkb:ZNF40(gene name synonym)|uniprotkb:Gate keeper of apoptosis-activating protein(gene name synonym)|uniprotkb:Cirhin interaction protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833802|imex:IM-21659-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N|uniprotkb:O15294(identity)|entrezgene/locuslink:8473(identity)|ddbj/embl/genbank:BC014434(identity) refseq:NP_002105.3|ensembl:ENSG00000095951(gene)|ensembl:ENST00000379388(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016604"(nuclear body)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR034729|interpro:IPR036236|mint:P15822|rcsb pdb:1BBO|rcsb pdb:3ZNF|rcsb pdb:4ZNF|uniprotkb:P15822(identity)|entrezgene/locuslink:3096(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 rogid:rugwzqsTO0X8mJ5Zy3msTqc6dr09606 intact-crc:63F534F755729516|rigid://ozfeNRbx8c48nLzYo1eLW3RLw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15294 uniprotkb:O15047 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 intact:EBI-540779|uniprotkb:A6NP62|uniprotkb:Q6PIF3|uniprotkb:Q8TAJ6|intact:EBI-28969638|ensembl:ENSP00000262519|ensembl:ENSP00000507683 psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:set1a_human(display_long)|uniprotkb:KMT2F(gene name synonym)|uniprotkb:SET domain-containing protein 1A(gene name synonym)|uniprotkb:Set1/Ash2 histone methyltransferase complex subunit SET1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 2F(gene name synonym)|uniprotkb:SETD1A(gene name)|psi-mi:SETD1A(display_short)|uniprotkb:KIAA0339(gene name synonym)|uniprotkb:SET1(gene name synonym)|uniprotkb:SET1A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833802|imex:IM-21659-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N|uniprotkb:O15294(identity)|entrezgene/locuslink:8473(identity)|ddbj/embl/genbank:BC014434(identity) refseq:NP_055527.1|refseq:XP_006721169.1|ensembl:ENSP00000262519|ensembl:ENSP00000507683|reactome:R-HSA-8936459|reactome:R-HSA-3214841|ensembl:ENSG00000099381(gene)|ensembl:ENST00000262519(transcript)|ensembl:ENST00000684162(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007420"(brain development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR024657|interpro:IPR034467|interpro:IPR035979|interpro:IPR037841|interpro:IPR044570|mint:O15047|go:"GO:0048188"(Set1C/COMPASS complex)|rcsb pdb:3S8S|rcsb pdb:3UVN|rcsb pdb:4EWR|refseq:XP_005255780.1|refseq:XP_016879398.1|dip:DIP-33494N|uniprotkb:O15047(identity)|entrezgene/locuslink:9739(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 rogid:nx0uWEVFas1w2NmuG73lCObAULE9606 intact-crc:63F534F755729516|rigid://ozfeNRbx8c48nLzYo1eLW3RLw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15294 uniprotkb:P78371 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300 psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833802|imex:IM-21659-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N|uniprotkb:O15294(identity)|entrezgene/locuslink:8473(identity)|ddbj/embl/genbank:BC014434(identity) refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695|uniprotkb:P78371(identity)|entrezgene/locuslink:10576(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606 intact-crc:63F534F755729516|rigid://ozfeNRbx8c48nLzYo1eLW3RLw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15294 uniprotkb:Q96EZ8 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 intact:EBI-348259|ensembl:ENSP00000345358|ensembl:ENSP00000448056|uniprotkb:O14742|uniprotkb:O75497|uniprotkb:Q6VN53|uniprotkb:Q7Z372 psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:mcrs1_human(display_long)|uniprotkb:MCRS1(gene name)|psi-mi:MCRS1(display_short)|uniprotkb:MSP58(gene name synonym)|uniprotkb:58 kDa microspherule protein(gene name synonym)|uniprotkb:Cell cycle-regulated factor p78(gene name synonym)|uniprotkb:MCRS2(gene name synonym)|uniprotkb:INO80Q(gene name synonym)|uniprotkb:INO80 complex subunit J(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833802|imex:IM-21659-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N|uniprotkb:O15294(identity)|entrezgene/locuslink:8473(identity)|ddbj/embl/genbank:BC014434(identity) ensembl:ENSG00000187778(gene)|ensembl:ENST00000343810(transcript)|ensembl:ENST00000550165(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005844"(polysome)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010521"(telomerase inhibitor activity)|go:"GO:0030425"(dendrite)|go:"GO:0031011"(Ino80 complex)|go:"GO:0034046"("poly(G) binding")|go:"GO:0043204"(perikaryon)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR025999|interpro:IPR037912|mint:Q96EZ8|reactome:R-HSA-3214847|go:"GO:0043984"(histone H4-K16 acetylation)|reactome:R-HSA-5689603|reactome:R-HSA-5696394|refseq:NP_001012300.1|refseq:NP_006328.2|refseq:NP_001265270.1|refseq:XP_005268629.1|refseq:XP_016874178.1|refseq:XP_016874179.1|uniprotkb:Q96EZ8(identity)|entrezgene/locuslink:10445(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 rogid:b6u2XbKLMDkL1zbLTPBjq9J23Zs9606 intact-crc:63F534F755729516|rigid://ozfeNRbx8c48nLzYo1eLW3RLw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15294 uniprotkb:P51571 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 intact:EBI-1054539|uniprotkb:Q53XY1|uniprotkb:A8K378|ensembl:ENSP00000317331|ensembl:ENSP00000359103|ensembl:ENSP00000359104 psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:ssrd_human(display_long)|uniprotkb:Signal sequence receptor subunit delta(gene name synonym)|uniprotkb:SSR4(gene name)|psi-mi:SSR4(display_short)|uniprotkb:TRAPD(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833802|imex:IM-21659-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N|uniprotkb:O15294(identity)|entrezgene/locuslink:8473(identity)|ddbj/embl/genbank:BC014434(identity) refseq:NP_001191455.1|refseq:NP_006271.1|refseq:XP_011529488.1|refseq:XP_011529489.1|ensembl:ENSG00000180879(gene)|ensembl:ENST00000320857(transcript)|ensembl:ENST00000370086(transcript)|ensembl:ENST00000370087(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008855(Translocon-associated)|mint:P51571|reactome:R-HSA-1799339|uniprotkb:P51571(identity)|entrezgene/locuslink:6748(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 rogid:2SNgZQH/jwi61UcuHUf7RYKZH589606 intact-crc:63F534F755729516|rigid://ozfeNRbx8c48nLzYo1eLW3RLw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y483 uniprotkb:Q96EA4 intact:EBI-725816|uniprotkb:A6NGQ9|uniprotkb:Q9UES9|uniprotkb:Q9UP40|uniprotkb:A8K2Q3|uniprotkb:B1AKT5|intact:EBI-11028207|uniprotkb:Q96G26|uniprotkb:B1AKT6|ensembl:ENSP00000359321 intact:EBI-715381|uniprotkb:Q8TEC8|uniprotkb:Q9HD44|uniprotkb:Q9NX97|uniprotkb:C9JS47|ensembl:ENSP00000265295|uniprotkb:B4E393 psi-mi:mtf2_human(display_long)|uniprotkb:PCL2(gene name synonym)|uniprotkb:Metal-response element DNA-binding protein M96(gene name synonym)|uniprotkb:Metal regulatory transcription factor 2(gene name synonym)|uniprotkb:Polycomb-like protein 2(gene name synonym)|uniprotkb:MTF2(gene name)|psi-mi:MTF2(display_short) psi-mi:spdly_human(display_long)|uniprotkb:SPDL1(gene name)|psi-mi:SPDL1(display_short)|uniprotkb:Arsenite-related gene 1 protein(gene name synonym)|uniprotkb:CCDC99(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 99(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.4A(gene name synonym)|uniprotkb:Spindle apparatus coiled-coil domain-containing protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833756|imex:IM-21659-32 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001157863.1|refseq:NP_001157865.1|refseq:NP_031384.1|refseq:XP_011539318.1|refseq:XP_016856165.1|ensembl:ENSG00000143033(gene)|ensembl:ENST00000370298(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042015|mint:Q9Y483|rcsb pdb:5XFR|reactome:R-HSA-212300|interpro:IPR042014|refseq:NP_001157864.1|uniprotkb:Q9Y483(identity)|ddbj/embl/genbank:BC010013(identity)|entrezgene/locuslink:22823(identity) refseq:NP_060255.3|ensembl:ENSG00000040275(gene)|ensembl:ENST00000265295(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0016477"(cell migration)|go:"GO:0019899"(enzyme binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0043515"(kinetochore binding)|go:"GO:0051301"(cell division)|interpro:IPR028593|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001316570.1|dip:DIP-47296N|uniprotkb:Q96EA4(identity)|entrezgene/locuslink:54908(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:Im8E6U/OPb8AEir43AUUDlU6F2o9606 rogid:CzXKB2VOL2ZBmQjyc4vGxQ0cTnY9606 intact-crc:7000D5A02D127248|rigid:oebbyEnO+0ug2lU+AeoK0DeftjU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y483 uniprotkb:A6NHQ4 intact:EBI-725816|uniprotkb:A6NGQ9|uniprotkb:Q9UES9|uniprotkb:Q9UP40|uniprotkb:A8K2Q3|uniprotkb:B1AKT5|intact:EBI-11028207|uniprotkb:Q96G26|uniprotkb:B1AKT6|ensembl:ENSP00000359321 intact:EBI-8831125|ensembl:ENSP00000483859|ensembl:ENSP00000484710 psi-mi:mtf2_human(display_long)|uniprotkb:PCL2(gene name synonym)|uniprotkb:Metal-response element DNA-binding protein M96(gene name synonym)|uniprotkb:Metal regulatory transcription factor 2(gene name synonym)|uniprotkb:Polycomb-like protein 2(gene name synonym)|uniprotkb:MTF2(gene name)|psi-mi:MTF2(display_short) psi-mi:epop_human(display_long)|uniprotkb:EPOP(gene name)|psi-mi:EPOP(display_short)|uniprotkb:C17orf96(gene name synonym)|uniprotkb:PRR28(gene name synonym)|uniprotkb:Proline-rich protein 28(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833756|imex:IM-21659-32 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001157863.1|refseq:NP_001157865.1|refseq:NP_031384.1|refseq:XP_011539318.1|refseq:XP_016856165.1|ensembl:ENSG00000143033(gene)|ensembl:ENST00000370298(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042015|mint:Q9Y483|rcsb pdb:5XFR|reactome:R-HSA-212300|interpro:IPR042014|refseq:NP_001157864.1|uniprotkb:Q9Y483(identity)|ddbj/embl/genbank:BC010013(identity)|entrezgene/locuslink:22823(identity) refseq:NP_001124149.1|ensembl:ENSG00000273604(gene)|ensembl:ENST00000613024(transcript)|ensembl:ENST00000621654(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005694"(chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0070449"(elongin complex)|interpro:IPR027971|mint:A6NHQ4|ensembl:ENSG00000277303(gene)|uniprotkb:A6NHQ4(identity)|entrezgene/locuslink:100170841(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:Im8E6U/OPb8AEir43AUUDlU6F2o9606 rogid:xxrapCjRxgY22pLac2F4zSS2bvk9606 intact-crc:7000D5A02D127248|rigid:oebbyEnO+0ug2lU+AeoK0DeftjU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y483 uniprotkb:O75530 intact:EBI-725816|uniprotkb:A6NGQ9|uniprotkb:Q9UES9|uniprotkb:Q9UP40|uniprotkb:A8K2Q3|uniprotkb:B1AKT5|intact:EBI-11028207|uniprotkb:Q96G26|uniprotkb:B1AKT6|ensembl:ENSP00000359321 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 psi-mi:mtf2_human(display_long)|uniprotkb:PCL2(gene name synonym)|uniprotkb:Metal-response element DNA-binding protein M96(gene name synonym)|uniprotkb:Metal regulatory transcription factor 2(gene name synonym)|uniprotkb:Polycomb-like protein 2(gene name synonym)|uniprotkb:MTF2(gene name)|psi-mi:MTF2(display_short) psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833756|imex:IM-21659-32 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001157863.1|refseq:NP_001157865.1|refseq:NP_031384.1|refseq:XP_011539318.1|refseq:XP_016856165.1|ensembl:ENSG00000143033(gene)|ensembl:ENST00000370298(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042015|mint:Q9Y483|rcsb pdb:5XFR|reactome:R-HSA-212300|interpro:IPR042014|refseq:NP_001157864.1|uniprotkb:Q9Y483(identity)|ddbj/embl/genbank:BC010013(identity)|entrezgene/locuslink:22823(identity) refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:O75530(identity)|entrezgene/locuslink:8726(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:Im8E6U/OPb8AEir43AUUDlU6F2o9606 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 intact-crc:7000D5A02D127248|rigid:oebbyEnO+0ug2lU+AeoK0DeftjU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y483 uniprotkb:Q15910 intact:EBI-725816|uniprotkb:A6NGQ9|uniprotkb:Q9UES9|uniprotkb:Q9UP40|uniprotkb:A8K2Q3|uniprotkb:B1AKT5|intact:EBI-11028207|uniprotkb:Q96G26|uniprotkb:B1AKT6|ensembl:ENSP00000359321 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 psi-mi:mtf2_human(display_long)|uniprotkb:PCL2(gene name synonym)|uniprotkb:Metal-response element DNA-binding protein M96(gene name synonym)|uniprotkb:Metal regulatory transcription factor 2(gene name synonym)|uniprotkb:Polycomb-like protein 2(gene name synonym)|uniprotkb:MTF2(gene name)|psi-mi:MTF2(display_short) psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833756|imex:IM-21659-32 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001157863.1|refseq:NP_001157865.1|refseq:NP_031384.1|refseq:XP_011539318.1|refseq:XP_016856165.1|ensembl:ENSG00000143033(gene)|ensembl:ENST00000370298(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042015|mint:Q9Y483|rcsb pdb:5XFR|reactome:R-HSA-212300|interpro:IPR042014|refseq:NP_001157864.1|uniprotkb:Q9Y483(identity)|ddbj/embl/genbank:BC010013(identity)|entrezgene/locuslink:22823(identity) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N|uniprotkb:Q15910(identity)|entrezgene/locuslink:2146(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:Im8E6U/OPb8AEir43AUUDlU6F2o9606 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 intact-crc:7000D5A02D127248|rigid:oebbyEnO+0ug2lU+AeoK0DeftjU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y483 uniprotkb:Q09028 intact:EBI-725816|uniprotkb:A6NGQ9|uniprotkb:Q9UES9|uniprotkb:Q9UP40|uniprotkb:A8K2Q3|uniprotkb:B1AKT5|intact:EBI-11028207|uniprotkb:Q96G26|uniprotkb:B1AKT6|ensembl:ENSP00000359321 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 psi-mi:mtf2_human(display_long)|uniprotkb:PCL2(gene name synonym)|uniprotkb:Metal-response element DNA-binding protein M96(gene name synonym)|uniprotkb:Metal regulatory transcription factor 2(gene name synonym)|uniprotkb:Polycomb-like protein 2(gene name synonym)|uniprotkb:MTF2(gene name)|psi-mi:MTF2(display_short) psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833756|imex:IM-21659-32 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001157863.1|refseq:NP_001157865.1|refseq:NP_031384.1|refseq:XP_011539318.1|refseq:XP_016856165.1|ensembl:ENSG00000143033(gene)|ensembl:ENST00000370298(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042015|mint:Q9Y483|rcsb pdb:5XFR|reactome:R-HSA-212300|interpro:IPR042014|refseq:NP_001157864.1|uniprotkb:Q9Y483(identity)|ddbj/embl/genbank:BC010013(identity)|entrezgene/locuslink:22823(identity) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|entrezgene/locuslink:5928(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:Im8E6U/OPb8AEir43AUUDlU6F2o9606 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 intact-crc:7000D5A02D127248|rigid:oebbyEnO+0ug2lU+AeoK0DeftjU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y483 uniprotkb:Q96JN0 intact:EBI-725816|uniprotkb:A6NGQ9|uniprotkb:Q9UES9|uniprotkb:Q9UP40|uniprotkb:A8K2Q3|uniprotkb:B1AKT5|intact:EBI-11028207|uniprotkb:Q96G26|uniprotkb:B1AKT6|ensembl:ENSP00000359321 intact:EBI-746045|uniprotkb:Q9H945|uniprotkb:Q9Y457|ensembl:ENSP00000348298|ensembl:ENSP00000360138|ensembl:ENSP00000360144|ensembl:ENSP00000501560|ensembl:ENSP00000501639|ensembl:ENSP00000502633|intact:EBI-8833163|uniprotkb:D3DR47|uniprotkb:Q5VW16|uniprotkb:Q7Z723|uniprotkb:Q86T32|uniprotkb:Q86T33|uniprotkb:Q8N3L6|uniprotkb:Q8N655 psi-mi:mtf2_human(display_long)|uniprotkb:PCL2(gene name synonym)|uniprotkb:Metal-response element DNA-binding protein M96(gene name synonym)|uniprotkb:Metal regulatory transcription factor 2(gene name synonym)|uniprotkb:Polycomb-like protein 2(gene name synonym)|uniprotkb:MTF2(gene name)|psi-mi:MTF2(display_short) psi-mi:lcor_human(display_long)|uniprotkb:LCOR(gene name)|psi-mi:LCOR(display_short)|uniprotkb:C10orf12(gene name synonym)|uniprotkb:KIAA1795(gene name synonym)|uniprotkb:MLR2(gene name synonym)|uniprotkb:Mblk1-related protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833756|imex:IM-21659-32 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001157863.1|refseq:NP_001157865.1|refseq:NP_031384.1|refseq:XP_011539318.1|refseq:XP_016856165.1|ensembl:ENSG00000143033(gene)|ensembl:ENST00000370298(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042015|mint:Q9Y483|rcsb pdb:5XFR|reactome:R-HSA-212300|interpro:IPR042014|refseq:NP_001157864.1|uniprotkb:Q9Y483(identity)|ddbj/embl/genbank:BC010013(identity)|entrezgene/locuslink:22823(identity) ensembl:ENSG00000196233(gene)|ensembl:ENST00000356016(transcript)|ensembl:ENST00000371097(transcript)|ensembl:ENST00000371103(transcript)|ensembl:ENST00000675471(transcript)|ensembl:ENST00000675537(transcript)|ensembl:ENST00000675971(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|mint:Q96JN0|rcsb pdb:2COB|refseq:NP_001164236.1|refseq:NP_001164237.1|refseq:NP_115816.2|refseq:XP_016872275.1|refseq:XP_016872276.1|refseq:XP_016872277.1|refseq:NP_001333445.1|uniprotkb:Q8N655(identity)|entrezgene/locuslink:26148(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:Im8E6U/OPb8AEir43AUUDlU6F2o9606 rogid:cOnk6EDDff86yaG1uG+dxEQ1Z689606 intact-crc:7000D5A02D127248|rigid:oebbyEnO+0ug2lU+AeoK0DeftjU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y483 uniprotkb:Q15022 intact:EBI-725816|uniprotkb:A6NGQ9|uniprotkb:Q9UES9|uniprotkb:Q9UP40|uniprotkb:A8K2Q3|uniprotkb:B1AKT5|intact:EBI-11028207|uniprotkb:Q96G26|uniprotkb:B1AKT6|ensembl:ENSP00000359321 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 psi-mi:mtf2_human(display_long)|uniprotkb:PCL2(gene name synonym)|uniprotkb:Metal-response element DNA-binding protein M96(gene name synonym)|uniprotkb:Metal regulatory transcription factor 2(gene name synonym)|uniprotkb:Polycomb-like protein 2(gene name synonym)|uniprotkb:MTF2(gene name)|psi-mi:MTF2(display_short) psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833756|imex:IM-21659-32 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001157863.1|refseq:NP_001157865.1|refseq:NP_031384.1|refseq:XP_011539318.1|refseq:XP_016856165.1|ensembl:ENSG00000143033(gene)|ensembl:ENST00000370298(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042015|mint:Q9Y483|rcsb pdb:5XFR|reactome:R-HSA-212300|interpro:IPR042014|refseq:NP_001157864.1|uniprotkb:Q9Y483(identity)|ddbj/embl/genbank:BC010013(identity)|entrezgene/locuslink:22823(identity) dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:Q15022(identity)|entrezgene/locuslink:23512(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:Im8E6U/OPb8AEir43AUUDlU6F2o9606 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 intact-crc:7000D5A02D127248|rigid:oebbyEnO+0ug2lU+AeoK0DeftjU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y483 uniprotkb:Q16576 intact:EBI-725816|uniprotkb:A6NGQ9|uniprotkb:Q9UES9|uniprotkb:Q9UP40|uniprotkb:A8K2Q3|uniprotkb:B1AKT5|intact:EBI-11028207|uniprotkb:Q96G26|uniprotkb:B1AKT6|ensembl:ENSP00000359321 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 psi-mi:mtf2_human(display_long)|uniprotkb:PCL2(gene name synonym)|uniprotkb:Metal-response element DNA-binding protein M96(gene name synonym)|uniprotkb:Metal regulatory transcription factor 2(gene name synonym)|uniprotkb:Polycomb-like protein 2(gene name synonym)|uniprotkb:MTF2(gene name)|psi-mi:MTF2(display_short) psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833756|imex:IM-21659-32 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001157863.1|refseq:NP_001157865.1|refseq:NP_031384.1|refseq:XP_011539318.1|refseq:XP_016856165.1|ensembl:ENSG00000143033(gene)|ensembl:ENST00000370298(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042015|mint:Q9Y483|rcsb pdb:5XFR|reactome:R-HSA-212300|interpro:IPR042014|refseq:NP_001157864.1|uniprotkb:Q9Y483(identity)|ddbj/embl/genbank:BC010013(identity)|entrezgene/locuslink:22823(identity) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|entrezgene/locuslink:5931(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:Im8E6U/OPb8AEir43AUUDlU6F2o9606 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 intact-crc:7000D5A02D127248|rigid:oebbyEnO+0ug2lU+AeoK0DeftjU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y483 uniprotkb:Q92800 intact:EBI-725816|uniprotkb:A6NGQ9|uniprotkb:Q9UES9|uniprotkb:Q9UP40|uniprotkb:A8K2Q3|uniprotkb:B1AKT5|intact:EBI-11028207|uniprotkb:Q96G26|uniprotkb:B1AKT6|ensembl:ENSP00000359321 intact:EBI-8830732|uniprotkb:B4E3R7|uniprotkb:O43287|uniprotkb:A6NCH6|uniprotkb:Q14459|uniprotkb:Q53XP3|uniprotkb:B4DSS2|uniprotkb:B4DIJ1|uniprotkb:B4DIZ7|ensembl:ENSP00000404658|ensembl:ENSP00000466924 psi-mi:mtf2_human(display_long)|uniprotkb:PCL2(gene name synonym)|uniprotkb:Metal-response element DNA-binding protein M96(gene name synonym)|uniprotkb:Metal regulatory transcription factor 2(gene name synonym)|uniprotkb:Polycomb-like protein 2(gene name synonym)|uniprotkb:MTF2(gene name)|psi-mi:MTF2(display_short) psi-mi:ezh1_human(display_long)|uniprotkb:ENX-2(gene name synonym)|uniprotkb:Enhancer of zeste homolog 1(gene name synonym)|uniprotkb:KIAA0388(gene name synonym)|uniprotkb:EZH1(gene name)|psi-mi:EZH1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833756|imex:IM-21659-32 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001157863.1|refseq:NP_001157865.1|refseq:NP_031384.1|refseq:XP_011539318.1|refseq:XP_016856165.1|ensembl:ENSG00000143033(gene)|ensembl:ENST00000370298(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042015|mint:Q9Y483|rcsb pdb:5XFR|reactome:R-HSA-212300|interpro:IPR042014|refseq:NP_001157864.1|uniprotkb:Q9Y483(identity)|ddbj/embl/genbank:BC010013(identity)|entrezgene/locuslink:22823(identity) refseq:NP_001308008.1|refseq:NP_001308010.1|refseq:NP_001308011.1|refseq:NP_001982.2|dip:DIP-58580N|ensembl:ENSG00000108799(gene)|ensembl:ENST00000428826(transcript)|ensembl:ENST00000592743(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0021766"(hippocampus development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0031507"(heterochromatin assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR021654|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR032926|interpro:IPR041343|interpro:IPR041355|interpro:IPR044438|mint:Q92800|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|uniprotkb:Q92800(identity)|entrezgene/locuslink:2145(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:Im8E6U/OPb8AEir43AUUDlU6F2o9606 rogid:qp3eqBCgiaoA6VSSyqpW1d9YKN49606 intact-crc:7000D5A02D127248|rigid:oebbyEnO+0ug2lU+AeoK0DeftjU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BSM1 uniprotkb:Q8NHM5 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-3955564|uniprotkb:Q1RLM7|uniprotkb:Q8NCI2|uniprotkb:Q96HC7|uniprotkb:Q96SL0|uniprotkb:Q96T03|uniprotkb:Q9NS96|uniprotkb:Q9UF75|ensembl:ENSP00000366271|uniprotkb:A8MRS1 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:kdm2b_human(display_long)|uniprotkb:KDM2B(gene name)|psi-mi:KDM2B(display_short)|uniprotkb:CXXC2(gene name synonym)|uniprotkb:FBL10(gene name synonym)|uniprotkb:FBXL10(gene name synonym)|uniprotkb:JHDM1B(gene name synonym)|uniprotkb:PCCX2(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 2(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 10(gene name synonym)|uniprotkb:F-box protein FBL10(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 10(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1B(gene name synonym)|uniprotkb:Jumonji domain-containing EMSY-interactor methyltransferase motif protein(gene name synonym)|uniprotkb:Protein-containing CXXC domain 2(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1B(gene name synonym)|uniprotkb:NDY1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833957|imex:IM-21659-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5|uniprotkb:Q9BSM1(identity)|ddbj/embl/genbank:BC004952(identity)|entrezgene/locuslink:84759(identity) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENST00000377071(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0021555"(midbrain-hindbrain boundary morphogenesis)|go:"GO:0021592"(fourth ventricle development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021678"(third ventricle development)|go:"GO:0021993"(initiation of neural tube closure)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|interpro:IPR041070|interpro:IPR041667|mint:Q8NHM5|rcsb pdb:4O64|rcsb pdb:5JH5|rcsb pdb:6BVA|reactome:R-HSA-3214842|refseq:NP_115979.3|ensembl:ENSG00000089094(gene)|refseq:NP_001005366.1|uniprotkb:Q8NHM5(identity)|entrezgene/locuslink:84678(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:tnMbfP2oxwaaDyHHAigNt5hx4hM9606 intact-crc:670291010091043A|rigid:dzFCxgISgfSqMFfpP5nBBSkVysg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BSM1 uniprotkb:Q8N488 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833957|imex:IM-21659-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5|uniprotkb:Q9BSM1(identity)|ddbj/embl/genbank:BC004952(identity)|entrezgene/locuslink:84759(identity) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|uniprotkb:Q8N488(identity)|entrezgene/locuslink:23429(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 intact-crc:670291010091043A|rigid:dzFCxgISgfSqMFfpP5nBBSkVysg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BSM1 uniprotkb:Q06587 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833957|imex:IM-21659-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5|uniprotkb:Q9BSM1(identity)|ddbj/embl/genbank:BC004952(identity)|entrezgene/locuslink:84759(identity) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 intact-crc:670291010091043A|rigid:dzFCxgISgfSqMFfpP5nBBSkVysg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BSM1 uniprotkb:Q8TE76 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-3940432|uniprotkb:Q5JUK7|uniprotkb:Q96MZ2|uniprotkb:Q9HAI7|intact:EBI-28969055|ensembl:ENSP00000347821|uniprotkb:A1YR23|uniprotkb:A1YR24|uniprotkb:H7BXF1 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:morc4_human(display_long)|uniprotkb:MORC4(gene name)|psi-mi:MORC4(display_short)|uniprotkb:ZCWCC2(gene name synonym)|uniprotkb:Zinc finger CW-type coiled-coil domain protein 2(gene name synonym)|uniprotkb:ZCW4(gene name synonym)|uniprotkb:Zinc finger CW-type domain protein 4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833957|imex:IM-21659-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5|uniprotkb:Q9BSM1(identity)|ddbj/embl/genbank:BC004952(identity)|entrezgene/locuslink:84759(identity) ensembl:ENST00000255495|ensembl:ENSP00000255495|ensembl:ENSP00000347821|ensembl:ENSG00000133131(gene)|ensembl:ENST00000355610(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|interpro:IPR011124(Zinc finger, CW-type)|interpro:IPR036890|interpro:IPR041006|mint:Q8TE76|rcsb pdb:7K7T|refseq:NP_078933.3|refseq:NP_001078823.1|uniprotkb:Q8TE76(identity)|entrezgene/locuslink:79710(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:4ZXYEyXqgZ18LMwuAgPTsqRtPgw9606 intact-crc:670291010091043A|rigid:dzFCxgISgfSqMFfpP5nBBSkVysg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BSM1 uniprotkb:Q5H9F3 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-8833946|uniprotkb:Q5H9F4|uniprotkb:Q9Y528|uniprotkb:Q8TEN3|uniprotkb:B5MDQ8|uniprotkb:Q6ZVE0|uniprotkb:Q5H9F2|ensembl:ENSP00000218147|ensembl:ENSP00000437775 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:bcorl_human(display_long)|uniprotkb:BCORL1(gene name)|psi-mi:BCORL1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833957|imex:IM-21659-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5|uniprotkb:Q9BSM1(identity)|ddbj/embl/genbank:BC004952(identity)|entrezgene/locuslink:84759(identity) ensembl:ENSP00000218147|ensembl:ENSP00000437775|refseq:NP_068765.3|dip:DIP-60148N|ensembl:ENSG00000085185(gene)|ensembl:ENST00000218147(transcript)|ensembl:ENST00000540052(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q5H9F3|rcsb pdb:4HPM|rcsb pdb:5JH5|uniprotkb:Q5H9F3(identity)|entrezgene/locuslink:63035(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:uQdpjjO3QnnX19nR1Ky76HjCdhw9606 intact-crc:670291010091043A|rigid:dzFCxgISgfSqMFfpP5nBBSkVysg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BSM1 uniprotkb:Q6W2J9 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833957|imex:IM-21659-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5|uniprotkb:Q9BSM1(identity)|ddbj/embl/genbank:BC004952(identity)|entrezgene/locuslink:84759(identity) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N|uniprotkb:Q6W2J9(identity)|entrezgene/locuslink:54880(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 intact-crc:670291010091043A|rigid:dzFCxgISgfSqMFfpP5nBBSkVysg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BSM1 uniprotkb:Q9HC52 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833957|imex:IM-21659-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5|uniprotkb:Q9BSM1(identity)|ddbj/embl/genbank:BC004952(identity)|entrezgene/locuslink:84759(identity) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N|uniprotkb:Q9HC52(identity)|entrezgene/locuslink:57332(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 intact-crc:670291010091043A|rigid:dzFCxgISgfSqMFfpP5nBBSkVysg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BSM1 uniprotkb:P63208 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833957|imex:IM-21659-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5|uniprotkb:Q9BSM1(identity)|ddbj/embl/genbank:BC004952(identity)|entrezgene/locuslink:84759(identity) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|entrezgene/locuslink:6500(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 intact-crc:670291010091043A|rigid:dzFCxgISgfSqMFfpP5nBBSkVysg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BSM1 uniprotkb:Q8IY57 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833957|imex:IM-21659-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5|uniprotkb:Q9BSM1(identity)|ddbj/embl/genbank:BC004952(identity)|entrezgene/locuslink:84759(identity) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|entrezgene/locuslink:10138(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 intact-crc:670291010091043A|rigid:dzFCxgISgfSqMFfpP5nBBSkVysg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BSM1 uniprotkb:P10809 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-352528|ensembl:ENSP00000340019|ensembl:ENSP00000373620|ensembl:ENSP00000396460|ensembl:ENSP00000402478|ensembl:ENSP00000412227|ensembl:ENSP00000412717|ensembl:ENSP00000414446|ensembl:ENSP00000503139|ensembl:ENSP00000503894|uniprotkb:Q38L19|uniprotkb:B2R5M6|uniprotkb:Q9UCR6|uniprotkb:B7Z712 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:ch60_human(display_long)|uniprotkb:HSPD1(gene name)|psi-mi:HSPD1(display_short)|uniprotkb:HSP60(gene name synonym)|uniprotkb:Heat shock protein 60(gene name synonym)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 60(gene name synonym)|uniprotkb:Mitochondrial matrix protein P1(gene name synonym)|uniprotkb:P60 lymphocyte protein(gene name synonym)|uniprotkb:HuCHA60(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833957|imex:IM-21659-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5|uniprotkb:Q9BSM1(identity)|ddbj/embl/genbank:BC004952(identity)|entrezgene/locuslink:84759(identity) refseq:NP_002147.2|refseq:NP_955472.1|ensembl:ENSG00000144381(gene)|ensembl:ENST00000345042(transcript)|ensembl:ENST00000388968(transcript)|ensembl:ENST00000418022(transcript)|ensembl:ENST00000426480(transcript)|ensembl:ENST00000428204(transcript)|ensembl:ENST00000439605(transcript)|ensembl:ENST00000452200(transcript)|ensembl:ENST00000677913(transcript)|ensembl:ENST00000678761(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002039"(p53 binding)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0002842"(positive regulation of T cell mediated immune response to tumor cell)|go:"GO:0002931"(response to ischemia)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033198"(response to ATP)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034186"(apolipoprotein A-I binding)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042588"(zymogen granule)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005769"(early endosome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030135"(coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0045121"(membrane raft)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0048291"(isotype switching to IgG isotypes)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051604"(protein maturation)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071866"(negative regulation of apoptotic process in bone marrow cell)|go:"GO:0097225"(sperm midpiece)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140030"(modification-dependent protein binding)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR018370|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P10809|rcsb pdb:4PJ1|rcsb pdb:6HT7|rcsb pdb:6MRC|rcsb pdb:6MRD|rcsb pdb:7AZP|reactome:R-HSA-1268020|reactome:R-HSA-8869496|dip:DIP-58N|uniprotkb:P10809(identity)|entrezgene/locuslink:3329(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:syB2vt66Cpr2mJROfbxoPevoiRE9606 intact-crc:670291010091043A|rigid:dzFCxgISgfSqMFfpP5nBBSkVysg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BSM1 uniprotkb:Q99496 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833957|imex:IM-21659-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5|uniprotkb:Q9BSM1(identity)|ddbj/embl/genbank:BC004952(identity)|entrezgene/locuslink:84759(identity) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|entrezgene/locuslink:6045(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 intact-crc:670291010091043A|rigid:dzFCxgISgfSqMFfpP5nBBSkVysg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BSM1 uniprotkb:Q9UN30 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-6911404|ensembl:ENSP00000369380|uniprotkb:B2RA08|uniprotkb:Q5H969|uniprotkb:B0FZN6|uniprotkb:Q5H968 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:scml1_human(display_long)|uniprotkb:SCML1(gene name)|psi-mi:SCML1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833957|imex:IM-21659-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5|uniprotkb:Q9BSM1(identity)|ddbj/embl/genbank:BC004952(identity)|entrezgene/locuslink:84759(identity) ensembl:ENSG00000047634(gene)|ensembl:ENST00000380041(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q9UN30|refseq:XP_016885212.1|refseq:XP_006724571.1|refseq:NP_001032624.1|refseq:NP_001032625.1|refseq:NP_001032629.1|refseq:NP_006737.2|uniprotkb:Q9UN30(identity)|entrezgene/locuslink:6322(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:/eJ/2Xuw4P5GzHy1wGRxnYZ4hvY9606 intact-crc:670291010091043A|rigid:dzFCxgISgfSqMFfpP5nBBSkVysg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BSM1 uniprotkb:Q93009 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-302474|uniprotkb:A6NMY8|intact:EBI-28988230|ensembl:ENSP00000343535|uniprotkb:B7Z815|uniprotkb:H0Y3G8 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:ubp7_human(display_long)|uniprotkb:USP7(gene name)|psi-mi:USP7(display_short)|uniprotkb:HAUSP(gene name synonym)|uniprotkb:Ubiquitin thioesterase 7(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 7(gene name synonym)|uniprotkb:Deubiquitinating enzyme 7(gene name synonym)|uniprotkb:Herpesvirus-associated ubiquitin-specific protease(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8833957|imex:IM-21659-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5|uniprotkb:Q9BSM1(identity)|ddbj/embl/genbank:BC004952(identity)|entrezgene/locuslink:84759(identity) rcsb pdb:4PYZ|rcsb pdb:4WPH|rcsb pdb:4WPI|rcsb pdb:4YOC|rcsb pdb:4YSI|rcsb pdb:4Z96|rcsb pdb:4Z97|rcsb pdb:5C56|rcsb pdb:5C6D|rcsb pdb:5FWI|rcsb pdb:5GG4|rcsb pdb:5J7T|rcsb pdb:5JTJ|rcsb pdb:5JTV|rcsb pdb:5KYB|rcsb pdb:4M5X|rcsb pdb:5KYC|rcsb pdb:5KYD|rcsb pdb:5KYE|rcsb pdb:5KYF|interpro:IPR029346|interpro:IPR038765|mint:Q93009|rcsb pdb:1NB8|rcsb pdb:1NBF|rcsb pdb:1YY6|rcsb pdb:1YZE|rcsb pdb:2F1W|rcsb pdb:2F1X|rcsb pdb:2F1Y|rcsb pdb:2F1Z|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2FOP|rcsb pdb:2KVR|rcsb pdb:2XXN|rcsb pdb:2YLM|rcsb pdb:3MQR|rcsb pdb:3MQS|rcsb pdb:4JJQ|rcsb pdb:4KG9|rcsb pdb:4M5W|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050821"(protein stabilization)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901537"(positive regulation of DNA demethylation)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904353"(regulation of telomere capping)|go:"GO:1905279"(regulation of retrograde transport, endosome to Golgi)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR018200|interpro:IPR024729|interpro:IPR028889|ensembl:ENSG00000187555(gene)|ensembl:ENST00000344836(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|rcsb pdb:5N9R|rcsb pdb:5N9T|rcsb pdb:5NGE|rcsb pdb:5NGF|rcsb pdb:5UQV|rcsb pdb:5UQX|rcsb pdb:5VS6|rcsb pdb:5VSB|rcsb pdb:5VSK|rcsb pdb:5WHC|rcsb pdb:6F5H|rcsb pdb:6M1K|rcsb pdb:6P5L|rcsb pdb:6VN2|rcsb pdb:6VN3|rcsb pdb:6VN4|rcsb pdb:6VN5|rcsb pdb:6VN6|rcsb pdb:7CM2|reactome:R-HSA-5689880|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804757|reactome:R-HSA-8866652|reactome:R-HSA-8948747|refseq:NP_001273386.1|refseq:NP_003461.2|refseq:NP_001308787.1|ensembl:ENSP00000343535|ensembl:ENST00000381886|ensembl:ENSP00000371310|dip:DIP-29053N|uniprotkb:Q93009(identity)|entrezgene/locuslink:7874(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:V+PXXBRM2zwlGQaeFiyjaQ9yf+A9606 intact-crc:670291010091043A|rigid:dzFCxgISgfSqMFfpP5nBBSkVysg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35227 uniprotkb:O95503 intact:EBI-2129767|uniprotkb:A6NGD8|ensembl:ENSP00000478517|ensembl:ENSP00000478970|ensembl:ENSP00000482063|ensembl:ENSP00000482815|ensembl:ENSP00000488868|ensembl:ENSP00000488872 intact:EBI-3951758|uniprotkb:A8KAH0|uniprotkb:Q96EM5|intact:EBI-28986885|ensembl:ENSP00000384490 psi-mi:pcgf2_human(display_long)|uniprotkb:PCGF2(gene name)|psi-mi:PCGF2(display_short)|uniprotkb:MEL18(gene name synonym)|uniprotkb:RNF110(gene name synonym)|uniprotkb:ZNF144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym) psi-mi:cbx6_human(display_long)|uniprotkb:CBX6(gene name)|psi-mi:CBX6(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834019|imex:IM-21659-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009075.1|refseq:XP_016880505.1|refseq:XP_005257697.1|refseq:XP_005257698.1|refseq:XP_005257699.1|dip:DIP-41880N|ensembl:ENSG00000277258(gene)|ensembl:ENSG00000278644(gene)|ensembl:ENST00000610440(transcript)|ensembl:ENST00000611883(transcript)|ensembl:ENST00000616199(transcript)|ensembl:ENST00000620225(transcript)|ensembl:ENST00000631566(transcript)|ensembl:ENST00000631610(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35227|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-5617472|reactome:R-HSA-8953750|uniprotkb:P35227(identity)|ddbj/embl/genbank:BC004858(identity)|entrezgene/locuslink:7703(identity) refseq:NP_001290423.1|ensembl:ENSG00000183741(gene)|refseq:NP_055107.3|ensembl:ENST00000407418(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:O95503|rcsb pdb:3GV6|rcsb pdb:3I90|reactome:R-HSA-2559580|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSP00000384490|dip:DIP-48605N|uniprotkb:O95503(identity)|entrezgene/locuslink:23466(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:zppw56VrEl6gEFwtJMCN5cQkPxI9606 rogid:4iNHCYe1bjb/JcurXP1iGoO/2uA9606 intact-crc:2111B9CB81EF8A39|rigid:uW9BG9WI/Tb7tKCdLqzR/wjUWyQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35227 uniprotkb:Q8N488 intact:EBI-2129767|uniprotkb:A6NGD8|ensembl:ENSP00000478517|ensembl:ENSP00000478970|ensembl:ENSP00000482063|ensembl:ENSP00000482815|ensembl:ENSP00000488868|ensembl:ENSP00000488872 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 psi-mi:pcgf2_human(display_long)|uniprotkb:PCGF2(gene name)|psi-mi:PCGF2(display_short)|uniprotkb:MEL18(gene name synonym)|uniprotkb:RNF110(gene name synonym)|uniprotkb:ZNF144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym) psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834019|imex:IM-21659-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009075.1|refseq:XP_016880505.1|refseq:XP_005257697.1|refseq:XP_005257698.1|refseq:XP_005257699.1|dip:DIP-41880N|ensembl:ENSG00000277258(gene)|ensembl:ENSG00000278644(gene)|ensembl:ENST00000610440(transcript)|ensembl:ENST00000611883(transcript)|ensembl:ENST00000616199(transcript)|ensembl:ENST00000620225(transcript)|ensembl:ENST00000631566(transcript)|ensembl:ENST00000631610(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35227|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-5617472|reactome:R-HSA-8953750|uniprotkb:P35227(identity)|ddbj/embl/genbank:BC004858(identity)|entrezgene/locuslink:7703(identity) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|uniprotkb:Q8N488(identity)|entrezgene/locuslink:23429(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:zppw56VrEl6gEFwtJMCN5cQkPxI9606 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 intact-crc:2111B9CB81EF8A39|rigid:uW9BG9WI/Tb7tKCdLqzR/wjUWyQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35227 uniprotkb:P78364 intact:EBI-2129767|uniprotkb:A6NGD8|ensembl:ENSP00000478517|ensembl:ENSP00000478970|ensembl:ENSP00000482063|ensembl:ENSP00000482815|ensembl:ENSP00000488868|ensembl:ENSP00000488872 intact:EBI-725403|uniprotkb:Q8WVM3|uniprotkb:Q9BU63|uniprotkb:D3DUV4|ensembl:ENSP00000437659|ensembl:ENSP00000440674 psi-mi:pcgf2_human(display_long)|uniprotkb:PCGF2(gene name)|psi-mi:PCGF2(display_short)|uniprotkb:MEL18(gene name synonym)|uniprotkb:RNF110(gene name synonym)|uniprotkb:ZNF144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym) psi-mi:phc1_human(display_long)|uniprotkb:Early development regulatory protein 1(gene name synonym)|uniprotkb:PHC1(gene name)|psi-mi:PHC1(display_short)|uniprotkb:EDR1(gene name synonym)|uniprotkb:PH1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834019|imex:IM-21659-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009075.1|refseq:XP_016880505.1|refseq:XP_005257697.1|refseq:XP_005257698.1|refseq:XP_005257699.1|dip:DIP-41880N|ensembl:ENSG00000277258(gene)|ensembl:ENSG00000278644(gene)|ensembl:ENST00000610440(transcript)|ensembl:ENST00000611883(transcript)|ensembl:ENST00000616199(transcript)|ensembl:ENST00000620225(transcript)|ensembl:ENST00000631566(transcript)|ensembl:ENST00000631610(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35227|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-5617472|reactome:R-HSA-8953750|uniprotkb:P35227(identity)|ddbj/embl/genbank:BC004858(identity)|entrezgene/locuslink:7703(identity) refseq:NP_004417.2|ensembl:ENSG00000111752(gene)|ensembl:ENST00000543824(transcript)|ensembl:ENST00000544916(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:P78364|rcsb pdb:2L8E|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|dip:DIP-44567N|uniprotkb:P78364(identity)|entrezgene/locuslink:1911(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:zppw56VrEl6gEFwtJMCN5cQkPxI9606 rogid:0dDjrgvWcP5Sx8h+qUj7awuM3ko9606 intact-crc:2111B9CB81EF8A39|rigid:uW9BG9WI/Tb7tKCdLqzR/wjUWyQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35227 uniprotkb:Q9HC52 intact:EBI-2129767|uniprotkb:A6NGD8|ensembl:ENSP00000478517|ensembl:ENSP00000478970|ensembl:ENSP00000482063|ensembl:ENSP00000482815|ensembl:ENSP00000488868|ensembl:ENSP00000488872 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 psi-mi:pcgf2_human(display_long)|uniprotkb:PCGF2(gene name)|psi-mi:PCGF2(display_short)|uniprotkb:MEL18(gene name synonym)|uniprotkb:RNF110(gene name synonym)|uniprotkb:ZNF144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym) psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834019|imex:IM-21659-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009075.1|refseq:XP_016880505.1|refseq:XP_005257697.1|refseq:XP_005257698.1|refseq:XP_005257699.1|dip:DIP-41880N|ensembl:ENSG00000277258(gene)|ensembl:ENSG00000278644(gene)|ensembl:ENST00000610440(transcript)|ensembl:ENST00000611883(transcript)|ensembl:ENST00000616199(transcript)|ensembl:ENST00000620225(transcript)|ensembl:ENST00000631566(transcript)|ensembl:ENST00000631610(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35227|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-5617472|reactome:R-HSA-8953750|uniprotkb:P35227(identity)|ddbj/embl/genbank:BC004858(identity)|entrezgene/locuslink:7703(identity) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N|uniprotkb:Q9HC52(identity)|entrezgene/locuslink:57332(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:zppw56VrEl6gEFwtJMCN5cQkPxI9606 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 intact-crc:2111B9CB81EF8A39|rigid:uW9BG9WI/Tb7tKCdLqzR/wjUWyQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35227 uniprotkb:Q8NDX5 intact:EBI-2129767|uniprotkb:A6NGD8|ensembl:ENSP00000478517|ensembl:ENSP00000478970|ensembl:ENSP00000482063|ensembl:ENSP00000482815|ensembl:ENSP00000488868|ensembl:ENSP00000488872 intact:EBI-1223801|uniprotkb:Q5HYF0|uniprotkb:Q6NSG2|uniprotkb:Q8NFT7|uniprotkb:Q8NFZ1|uniprotkb:Q8TBM2|uniprotkb:Q9H971|uniprotkb:Q9H9I4|uniprotkb:A2RRP9|ensembl:ENSP00000420271 psi-mi:pcgf2_human(display_long)|uniprotkb:PCGF2(gene name)|psi-mi:PCGF2(display_short)|uniprotkb:MEL18(gene name synonym)|uniprotkb:RNF110(gene name synonym)|uniprotkb:ZNF144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym) psi-mi:phc3_human(display_long)|uniprotkb:PHC3(gene name)|psi-mi:PHC3(display_short)|uniprotkb:EDR3(gene name synonym)|uniprotkb:PH3(gene name synonym)|uniprotkb:Homolog of polyhomeotic 3(gene name synonym)|uniprotkb:Early development regulatory protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834019|imex:IM-21659-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009075.1|refseq:XP_016880505.1|refseq:XP_005257697.1|refseq:XP_005257698.1|refseq:XP_005257699.1|dip:DIP-41880N|ensembl:ENSG00000277258(gene)|ensembl:ENSG00000278644(gene)|ensembl:ENST00000610440(transcript)|ensembl:ENST00000611883(transcript)|ensembl:ENST00000616199(transcript)|ensembl:ENST00000620225(transcript)|ensembl:ENST00000631566(transcript)|ensembl:ENST00000631610(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35227|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-5617472|reactome:R-HSA-8953750|uniprotkb:P35227(identity)|ddbj/embl/genbank:BC004858(identity)|entrezgene/locuslink:7703(identity) refseq:NP_079223.3|refseq:NP_001295045.1|ensembl:ENSP00000420271|ensembl:ENST00000495893|ensembl:ENSP00000420294|ensembl:ENST00000497658|ensembl:ENSP00000420454|ensembl:ENSG00000173889(gene)|ensembl:ENST00000494943(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:Q8NDX5|rcsb pdb:4PZN|rcsb pdb:4PZO|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q8NDX5(identity)|entrezgene/locuslink:80012(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:zppw56VrEl6gEFwtJMCN5cQkPxI9606 rogid:hB1EMs+lCv19uuJ1O7+QiVCUoo89606 intact-crc:2111B9CB81EF8A39|rigid:uW9BG9WI/Tb7tKCdLqzR/wjUWyQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35227 uniprotkb:Q99496 intact:EBI-2129767|uniprotkb:A6NGD8|ensembl:ENSP00000478517|ensembl:ENSP00000478970|ensembl:ENSP00000482063|ensembl:ENSP00000482815|ensembl:ENSP00000488868|ensembl:ENSP00000488872 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:pcgf2_human(display_long)|uniprotkb:PCGF2(gene name)|psi-mi:PCGF2(display_short)|uniprotkb:MEL18(gene name synonym)|uniprotkb:RNF110(gene name synonym)|uniprotkb:ZNF144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834019|imex:IM-21659-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009075.1|refseq:XP_016880505.1|refseq:XP_005257697.1|refseq:XP_005257698.1|refseq:XP_005257699.1|dip:DIP-41880N|ensembl:ENSG00000277258(gene)|ensembl:ENSG00000278644(gene)|ensembl:ENST00000610440(transcript)|ensembl:ENST00000611883(transcript)|ensembl:ENST00000616199(transcript)|ensembl:ENST00000620225(transcript)|ensembl:ENST00000631566(transcript)|ensembl:ENST00000631610(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35227|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-5617472|reactome:R-HSA-8953750|uniprotkb:P35227(identity)|ddbj/embl/genbank:BC004858(identity)|entrezgene/locuslink:7703(identity) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|entrezgene/locuslink:6045(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:zppw56VrEl6gEFwtJMCN5cQkPxI9606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 intact-crc:2111B9CB81EF8A39|rigid:uW9BG9WI/Tb7tKCdLqzR/wjUWyQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35227 uniprotkb:O00257 intact:EBI-2129767|uniprotkb:A6NGD8|ensembl:ENSP00000478517|ensembl:ENSP00000478970|ensembl:ENSP00000482063|ensembl:ENSP00000482815|ensembl:ENSP00000488868|ensembl:ENSP00000488872 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 psi-mi:pcgf2_human(display_long)|uniprotkb:PCGF2(gene name)|psi-mi:PCGF2(display_short)|uniprotkb:MEL18(gene name synonym)|uniprotkb:RNF110(gene name synonym)|uniprotkb:ZNF144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym) psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834019|imex:IM-21659-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009075.1|refseq:XP_016880505.1|refseq:XP_005257697.1|refseq:XP_005257698.1|refseq:XP_005257699.1|dip:DIP-41880N|ensembl:ENSG00000277258(gene)|ensembl:ENSG00000278644(gene)|ensembl:ENST00000610440(transcript)|ensembl:ENST00000611883(transcript)|ensembl:ENST00000616199(transcript)|ensembl:ENST00000620225(transcript)|ensembl:ENST00000631566(transcript)|ensembl:ENST00000631610(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35227|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-5617472|reactome:R-HSA-8953750|uniprotkb:P35227(identity)|ddbj/embl/genbank:BC004858(identity)|entrezgene/locuslink:7703(identity) refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|uniprotkb:O00257(identity)|entrezgene/locuslink:8535(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:zppw56VrEl6gEFwtJMCN5cQkPxI9606 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 intact-crc:2111B9CB81EF8A39|rigid:uW9BG9WI/Tb7tKCdLqzR/wjUWyQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35227 uniprotkb:Q9H3G5 intact:EBI-2129767|uniprotkb:A6NGD8|ensembl:ENSP00000478517|ensembl:ENSP00000478970|ensembl:ENSP00000482063|ensembl:ENSP00000482815|ensembl:ENSP00000488868|ensembl:ENSP00000488872 intact:EBI-357542|uniprotkb:Q6UX20|uniprotkb:Q8NBL7|uniprotkb:Q96AR7|uniprotkb:Q9HB41|ensembl:ENSP00000265394|ensembl:ENSP00000379572|ensembl:ENSP00000387164|intact:EBI-1058665|uniprotkb:A4D1A4 psi-mi:pcgf2_human(display_long)|uniprotkb:PCGF2(gene name)|psi-mi:PCGF2(display_short)|uniprotkb:MEL18(gene name synonym)|uniprotkb:RNF110(gene name synonym)|uniprotkb:ZNF144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym) psi-mi:cpvl_human(display_long)|uniprotkb:CPVL(gene name)|psi-mi:CPVL(display_short)|uniprotkb:VLP(gene name synonym)|uniprotkb:UNQ197/PRO223(orf name)|uniprotkb:PSEC0124(orf name)|uniprotkb:Carboxypeptidase, vitellogenic-like(gene name synonym)|uniprotkb:Vitellogenic carboxypeptidase-like protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834019|imex:IM-21659-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009075.1|refseq:XP_016880505.1|refseq:XP_005257697.1|refseq:XP_005257698.1|refseq:XP_005257699.1|dip:DIP-41880N|ensembl:ENSG00000277258(gene)|ensembl:ENSG00000278644(gene)|ensembl:ENST00000610440(transcript)|ensembl:ENST00000611883(transcript)|ensembl:ENST00000616199(transcript)|ensembl:ENST00000620225(transcript)|ensembl:ENST00000631566(transcript)|ensembl:ENST00000631610(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35227|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-5617472|reactome:R-HSA-8953750|uniprotkb:P35227(identity)|ddbj/embl/genbank:BC004858(identity)|entrezgene/locuslink:7703(identity) ensembl:ENSG00000106066(gene)|ensembl:ENST00000265394(transcript)|ensembl:ENST00000396276(transcript)|ensembl:ENST00000409850(transcript)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR029058|mint:Q9H3G5|refseq:NP_061902.2|refseq:NP_112601.3|refseq:XP_011513739.1|refseq:NP_001334981.1|refseq:NP_001334983.1|uniprotkb:Q9H3G5(identity)|entrezgene/locuslink:54504(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:zppw56VrEl6gEFwtJMCN5cQkPxI9606 rogid:antgab61u6D+KmbopQeowXqSqWQ9606 intact-crc:2111B9CB81EF8A39|rigid:uW9BG9WI/Tb7tKCdLqzR/wjUWyQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35227 uniprotkb:O95931 intact:EBI-2129767|uniprotkb:A6NGD8|ensembl:ENSP00000478517|ensembl:ENSP00000478970|ensembl:ENSP00000482063|ensembl:ENSP00000482815|ensembl:ENSP00000488868|ensembl:ENSP00000488872 intact:EBI-3923843|uniprotkb:Q86T17|ensembl:ENSP00000216133 psi-mi:pcgf2_human(display_long)|uniprotkb:PCGF2(gene name)|psi-mi:PCGF2(display_short)|uniprotkb:MEL18(gene name synonym)|uniprotkb:RNF110(gene name synonym)|uniprotkb:ZNF144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym) psi-mi:cbx7_human(display_long)|uniprotkb:CBX7(gene name)|psi-mi:CBX7(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834019|imex:IM-21659-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009075.1|refseq:XP_016880505.1|refseq:XP_005257697.1|refseq:XP_005257698.1|refseq:XP_005257699.1|dip:DIP-41880N|ensembl:ENSG00000277258(gene)|ensembl:ENSG00000278644(gene)|ensembl:ENST00000610440(transcript)|ensembl:ENST00000611883(transcript)|ensembl:ENST00000616199(transcript)|ensembl:ENST00000620225(transcript)|ensembl:ENST00000631566(transcript)|ensembl:ENST00000631610(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35227|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-5617472|reactome:R-HSA-8953750|uniprotkb:P35227(identity)|ddbj/embl/genbank:BC004858(identity)|entrezgene/locuslink:7703(identity) refseq:NP_783640.1|ensembl:ENSG00000100307(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|mint:O95931|rcsb pdb:2K1B|rcsb pdb:2L12|rcsb pdb:2L1B|rcsb pdb:3GS2|rcsb pdb:4MN3|rcsb pdb:5EPJ|rcsb pdb:6V2R|ensembl:ENST00000216133(transcript)|dip:DIP-44565N|uniprotkb:O95931(identity)|entrezgene/locuslink:23492(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:zppw56VrEl6gEFwtJMCN5cQkPxI9606 rogid:LDXV9srMj1BL2CaSSot1Bn0/EW49606 intact-crc:2111B9CB81EF8A39|rigid:uW9BG9WI/Tb7tKCdLqzR/wjUWyQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35227 uniprotkb:Q06587 intact:EBI-2129767|uniprotkb:A6NGD8|ensembl:ENSP00000478517|ensembl:ENSP00000478970|ensembl:ENSP00000482063|ensembl:ENSP00000482815|ensembl:ENSP00000488868|ensembl:ENSP00000488872 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 psi-mi:pcgf2_human(display_long)|uniprotkb:PCGF2(gene name)|psi-mi:PCGF2(display_short)|uniprotkb:MEL18(gene name synonym)|uniprotkb:RNF110(gene name synonym)|uniprotkb:ZNF144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym) psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834019|imex:IM-21659-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009075.1|refseq:XP_016880505.1|refseq:XP_005257697.1|refseq:XP_005257698.1|refseq:XP_005257699.1|dip:DIP-41880N|ensembl:ENSG00000277258(gene)|ensembl:ENSG00000278644(gene)|ensembl:ENST00000610440(transcript)|ensembl:ENST00000611883(transcript)|ensembl:ENST00000616199(transcript)|ensembl:ENST00000620225(transcript)|ensembl:ENST00000631566(transcript)|ensembl:ENST00000631610(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35227|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-5617472|reactome:R-HSA-8953750|uniprotkb:P35227(identity)|ddbj/embl/genbank:BC004858(identity)|entrezgene/locuslink:7703(identity) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:zppw56VrEl6gEFwtJMCN5cQkPxI9606 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 intact-crc:2111B9CB81EF8A39|rigid:uW9BG9WI/Tb7tKCdLqzR/wjUWyQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35227 uniprotkb:Q9BQE3 intact:EBI-2129767|uniprotkb:A6NGD8|ensembl:ENSP00000478517|ensembl:ENSP00000478970|ensembl:ENSP00000482063|ensembl:ENSP00000482815|ensembl:ENSP00000488868|ensembl:ENSP00000488872 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:pcgf2_human(display_long)|uniprotkb:PCGF2(gene name)|psi-mi:PCGF2(display_short)|uniprotkb:MEL18(gene name synonym)|uniprotkb:RNF110(gene name synonym)|uniprotkb:ZNF144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834019|imex:IM-21659-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009075.1|refseq:XP_016880505.1|refseq:XP_005257697.1|refseq:XP_005257698.1|refseq:XP_005257699.1|dip:DIP-41880N|ensembl:ENSG00000277258(gene)|ensembl:ENSG00000278644(gene)|ensembl:ENST00000610440(transcript)|ensembl:ENST00000611883(transcript)|ensembl:ENST00000616199(transcript)|ensembl:ENST00000620225(transcript)|ensembl:ENST00000631566(transcript)|ensembl:ENST00000631610(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35227|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-5617472|reactome:R-HSA-8953750|uniprotkb:P35227(identity)|ddbj/embl/genbank:BC004858(identity)|entrezgene/locuslink:7703(identity) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1|uniprotkb:Q9BQE3(identity)|entrezgene/locuslink:84790(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:zppw56VrEl6gEFwtJMCN5cQkPxI9606 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:2111B9CB81EF8A39|rigid:uW9BG9WI/Tb7tKCdLqzR/wjUWyQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35227 uniprotkb:Q8IXK0 intact:EBI-2129767|uniprotkb:A6NGD8|ensembl:ENSP00000478517|ensembl:ENSP00000478970|ensembl:ENSP00000482063|ensembl:ENSP00000482815|ensembl:ENSP00000488868|ensembl:ENSP00000488872 intact:EBI-713786|uniprotkb:Q8N306|uniprotkb:Q8TAG8|uniprotkb:A1L4Q1|uniprotkb:Q2TAL3|uniprotkb:Q5T0C1|uniprotkb:Q6NUJ6|uniprotkb:Q6ZQR1|uniprotkb:Q96BL4|uniprotkb:Q9Y4Y7|ensembl:ENSP00000257118|uniprotkb:D3DPR2|uniprotkb:A8KA40 psi-mi:pcgf2_human(display_long)|uniprotkb:PCGF2(gene name)|psi-mi:PCGF2(display_short)|uniprotkb:MEL18(gene name synonym)|uniprotkb:RNF110(gene name synonym)|uniprotkb:ZNF144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym) psi-mi:phc2_human(display_long)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:PHC2(gene name)|psi-mi:PHC2(display_short)|uniprotkb:EDR2(gene name synonym)|uniprotkb:PH2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834019|imex:IM-21659-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009075.1|refseq:XP_016880505.1|refseq:XP_005257697.1|refseq:XP_005257698.1|refseq:XP_005257699.1|dip:DIP-41880N|ensembl:ENSG00000277258(gene)|ensembl:ENSG00000278644(gene)|ensembl:ENST00000610440(transcript)|ensembl:ENST00000611883(transcript)|ensembl:ENST00000616199(transcript)|ensembl:ENST00000620225(transcript)|ensembl:ENST00000631566(transcript)|ensembl:ENST00000631610(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35227|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-5617472|reactome:R-HSA-8953750|uniprotkb:P35227(identity)|ddbj/embl/genbank:BC004858(identity)|entrezgene/locuslink:7703(identity) interpro:IPR038603|mint:Q8IXK0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR013761(Sterile alpha motif-type)|ensembl:ENSG00000134686(gene)|ensembl:ENST00000257118(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|refseq:NP_004418.2|refseq:NP_932157.1|refseq:XP_016856005.1|refseq:XP_016856006.1|refseq:XP_016856007.1|refseq:XP_005270627.1|dip:DIP-34464N|uniprotkb:Q8IXK0(identity)|entrezgene/locuslink:1912(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:zppw56VrEl6gEFwtJMCN5cQkPxI9606 rogid:7si/KU2tHoxviuCr70ncQERDWmY9606 intact-crc:2111B9CB81EF8A39|rigid:uW9BG9WI/Tb7tKCdLqzR/wjUWyQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35227 uniprotkb:Q14781 intact:EBI-2129767|uniprotkb:A6NGD8|ensembl:ENSP00000478517|ensembl:ENSP00000478970|ensembl:ENSP00000482063|ensembl:ENSP00000482815|ensembl:ENSP00000488868|ensembl:ENSP00000488872 intact:EBI-745934|uniprotkb:Q9BTB1|uniprotkb:Q0VDA5|ensembl:ENSP00000308750 psi-mi:pcgf2_human(display_long)|uniprotkb:PCGF2(gene name)|psi-mi:PCGF2(display_short)|uniprotkb:MEL18(gene name synonym)|uniprotkb:RNF110(gene name synonym)|uniprotkb:ZNF144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym) psi-mi:cbx2_human(display_long)|uniprotkb:CBX2(gene name)|psi-mi:CBX2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834019|imex:IM-21659-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009075.1|refseq:XP_016880505.1|refseq:XP_005257697.1|refseq:XP_005257698.1|refseq:XP_005257699.1|dip:DIP-41880N|ensembl:ENSG00000277258(gene)|ensembl:ENSG00000278644(gene)|ensembl:ENST00000610440(transcript)|ensembl:ENST00000611883(transcript)|ensembl:ENST00000616199(transcript)|ensembl:ENST00000620225(transcript)|ensembl:ENST00000631566(transcript)|ensembl:ENST00000631610(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35227|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-5617472|reactome:R-HSA-8953750|uniprotkb:P35227(identity)|ddbj/embl/genbank:BC004858(identity)|entrezgene/locuslink:7703(identity) refseq:NP_005180.1|refseq:NP_116036.1|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|go:"GO:0045137"(development of primary sexual characteristics)|interpro:IPR042796|mint:Q14781|rcsb pdb:2D9U|rcsb pdb:3H91|rcsb pdb:5EPK|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSG00000173894(gene)|ensembl:ENST00000310942(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|dip:DIP-48604N|uniprotkb:Q14781(identity)|entrezgene/locuslink:84733(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:zppw56VrEl6gEFwtJMCN5cQkPxI9606 rogid:220eC8UGlmAHHP2WAhZdAveHC3s9606 intact-crc:2111B9CB81EF8A39|rigid:uW9BG9WI/Tb7tKCdLqzR/wjUWyQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35227 uniprotkb:Q8IY57 intact:EBI-2129767|uniprotkb:A6NGD8|ensembl:ENSP00000478517|ensembl:ENSP00000478970|ensembl:ENSP00000482063|ensembl:ENSP00000482815|ensembl:ENSP00000488868|ensembl:ENSP00000488872 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 psi-mi:pcgf2_human(display_long)|uniprotkb:PCGF2(gene name)|psi-mi:PCGF2(display_short)|uniprotkb:MEL18(gene name synonym)|uniprotkb:RNF110(gene name synonym)|uniprotkb:ZNF144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym) psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834019|imex:IM-21659-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009075.1|refseq:XP_016880505.1|refseq:XP_005257697.1|refseq:XP_005257698.1|refseq:XP_005257699.1|dip:DIP-41880N|ensembl:ENSG00000277258(gene)|ensembl:ENSG00000278644(gene)|ensembl:ENST00000610440(transcript)|ensembl:ENST00000611883(transcript)|ensembl:ENST00000616199(transcript)|ensembl:ENST00000620225(transcript)|ensembl:ENST00000631566(transcript)|ensembl:ENST00000631610(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35227|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-5617472|reactome:R-HSA-8953750|uniprotkb:P35227(identity)|ddbj/embl/genbank:BC004858(identity)|entrezgene/locuslink:7703(identity) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|entrezgene/locuslink:10138(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:zppw56VrEl6gEFwtJMCN5cQkPxI9606 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 intact-crc:2111B9CB81EF8A39|rigid:uW9BG9WI/Tb7tKCdLqzR/wjUWyQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KNV8 uniprotkb:Q8N488 intact:EBI-2339807|uniprotkb:O15262|uniprotkb:D3DVN1|ensembl:ENSP00000354724|ensembl:ENSP00000420489 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 psi-mi:pcgf3_human(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym) psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834085|imex:IM-21659-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006306.2|refseq:NP_001304765.1|dip:DIP-52782N|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q3KNV8|uniprotkb:Q3KNV8(identity)|entrezgene/locuslink:10336(identity)|ddbj/embl/genbank:BC107061(identity) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|uniprotkb:Q8N488(identity)|entrezgene/locuslink:23429(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 intact-crc:3D0D4BE40CF378A6|rigid:8jKFzcATWFD0WHYfnkTlUXRq8No false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KNV8 uniprotkb:Q9UHV9 intact:EBI-2339807|uniprotkb:O15262|uniprotkb:D3DVN1|ensembl:ENSP00000354724|ensembl:ENSP00000420489 intact:EBI-359873|uniprotkb:Q9P0P7|uniprotkb:Q9UN05|ensembl:ENSP00000356989 psi-mi:pcgf3_human(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym) psi-mi:pfd2_human(display_long)|uniprotkb:HSPC231(orf name)|uniprotkb:PFDN2(gene name)|psi-mi:PFDN2(display_short)|uniprotkb:PFD2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834085|imex:IM-21659-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006306.2|refseq:NP_001304765.1|dip:DIP-52782N|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q3KNV8|uniprotkb:Q3KNV8(identity)|entrezgene/locuslink:10336(identity)|ddbj/embl/genbank:BC107061(identity) refseq:NP_036526.2|refseq:XP_011507926.1|ensembl:ENSG00000143256(gene)|ensembl:ENST00000368010(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|interpro:IPR027235|mint:Q9UHV9|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957|dip:DIP-27557N|uniprotkb:Q9UHV9(identity)|entrezgene/locuslink:5202(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606 rogid:rgr14h3vGyzHxHoNJtlHBQkvhUE9606 intact-crc:3D0D4BE40CF378A6|rigid:8jKFzcATWFD0WHYfnkTlUXRq8No false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KNV8 uniprotkb:P78371 intact:EBI-2339807|uniprotkb:O15262|uniprotkb:D3DVN1|ensembl:ENSP00000354724|ensembl:ENSP00000420489 intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300 psi-mi:pcgf3_human(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym) psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834085|imex:IM-21659-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006306.2|refseq:NP_001304765.1|dip:DIP-52782N|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q3KNV8|uniprotkb:Q3KNV8(identity)|entrezgene/locuslink:10336(identity)|ddbj/embl/genbank:BC107061(identity) refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695|uniprotkb:P78371(identity)|entrezgene/locuslink:10576(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606 rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606 intact-crc:3D0D4BE40CF378A6|rigid:8jKFzcATWFD0WHYfnkTlUXRq8No false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KNV8 uniprotkb:P40227 intact:EBI-2339807|uniprotkb:O15262|uniprotkb:D3DVN1|ensembl:ENSP00000354724|ensembl:ENSP00000420489 intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2 psi-mi:pcgf3_human(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym) psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834085|imex:IM-21659-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006306.2|refseq:NP_001304765.1|dip:DIP-52782N|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q3KNV8|uniprotkb:Q3KNV8(identity)|entrezgene/locuslink:10336(identity)|ddbj/embl/genbank:BC107061(identity) refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N|uniprotkb:P40227(identity)|entrezgene/locuslink:908(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606 rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606 intact-crc:3D0D4BE40CF378A6|rigid:8jKFzcATWFD0WHYfnkTlUXRq8No false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KNV8 uniprotkb:Q8WXX7 intact:EBI-2339807|uniprotkb:O15262|uniprotkb:D3DVN1|ensembl:ENSP00000354724|ensembl:ENSP00000420489 intact:EBI-2875359|ensembl:ENSP00000344087|uniprotkb:L7QET3|uniprotkb:L7QF75|uniprotkb:Q5D049|uniprotkb:Q9Y4F2|uniprotkb:A4D1Y9|uniprotkb:Q6PJU5 psi-mi:pcgf3_human(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym) psi-mi:auts2_human(display_long)|uniprotkb:AUTS2(gene name)|psi-mi:AUTS2(display_short)|uniprotkb:KIAA0442(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834085|imex:IM-21659-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006306.2|refseq:NP_001304765.1|dip:DIP-52782N|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q3KNV8|uniprotkb:Q3KNV8(identity)|entrezgene/locuslink:10336(identity)|ddbj/embl/genbank:BC107061(identity) ensembl:ENSG00000158321(gene)|ensembl:ENST00000342771(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048675"(axon extension)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0097484"(dendrite extension)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR023246|reactome:R-HSA-8939243|refseq:NP_001120703.1|refseq:NP_001120704.1|refseq:NP_056385.1|dip:DIP-61355N|uniprotkb:Q8WXX7(identity)|entrezgene/locuslink:26053(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606 rogid:8m3VWlXEISEyVwNmlwDFEEKl4Sg9606 intact-crc:3D0D4BE40CF378A6|rigid:8jKFzcATWFD0WHYfnkTlUXRq8No false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KNV8 uniprotkb:P19784 intact:EBI-2339807|uniprotkb:O15262|uniprotkb:D3DVN1|ensembl:ENSP00000354724|ensembl:ENSP00000420489 intact:EBI-347451|ensembl:ENSP00000262506 psi-mi:pcgf3_human(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym) psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834085|imex:IM-21659-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006306.2|refseq:NP_001304765.1|dip:DIP-52782N|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q3KNV8|uniprotkb:Q3KNV8(identity)|entrezgene/locuslink:10336(identity)|ddbj/embl/genbank:BC107061(identity) refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|uniprotkb:P19784(identity)|entrezgene/locuslink:1459(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 intact-crc:3D0D4BE40CF378A6|rigid:8jKFzcATWFD0WHYfnkTlUXRq8No false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KNV8 uniprotkb:Q5H9F3 intact:EBI-2339807|uniprotkb:O15262|uniprotkb:D3DVN1|ensembl:ENSP00000354724|ensembl:ENSP00000420489 intact:EBI-8833946|uniprotkb:Q5H9F4|uniprotkb:Q9Y528|uniprotkb:Q8TEN3|uniprotkb:B5MDQ8|uniprotkb:Q6ZVE0|uniprotkb:Q5H9F2|ensembl:ENSP00000218147|ensembl:ENSP00000437775 psi-mi:pcgf3_human(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym) psi-mi:bcorl_human(display_long)|uniprotkb:BCORL1(gene name)|psi-mi:BCORL1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834085|imex:IM-21659-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006306.2|refseq:NP_001304765.1|dip:DIP-52782N|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q3KNV8|uniprotkb:Q3KNV8(identity)|entrezgene/locuslink:10336(identity)|ddbj/embl/genbank:BC107061(identity) ensembl:ENSP00000218147|ensembl:ENSP00000437775|refseq:NP_068765.3|dip:DIP-60148N|ensembl:ENSG00000085185(gene)|ensembl:ENST00000218147(transcript)|ensembl:ENST00000540052(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q5H9F3|rcsb pdb:4HPM|rcsb pdb:5JH5|uniprotkb:Q5H9F3(identity)|entrezgene/locuslink:63035(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606 rogid:uQdpjjO3QnnX19nR1Ky76HjCdhw9606 intact-crc:3D0D4BE40CF378A6|rigid:8jKFzcATWFD0WHYfnkTlUXRq8No false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KNV8 uniprotkb:P61758 intact:EBI-2339807|uniprotkb:O15262|uniprotkb:D3DVN1|ensembl:ENSP00000354724|ensembl:ENSP00000420489 intact:EBI-357430|ensembl:ENSP00000286428|uniprotkb:Q15765|uniprotkb:O55228|uniprotkb:Q5JT81|uniprotkb:Q86X96|uniprotkb:B2R8L5|uniprotkb:B4DWR3|uniprotkb:F5H2A7 psi-mi:pcgf3_human(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym) psi-mi:pfd3_human(display_long)|uniprotkb:VBP1(gene name)|psi-mi:VBP1(display_short)|uniprotkb:PFDN3(gene name synonym)|uniprotkb:von Hippel-Lindau-binding protein 1(gene name synonym)|uniprotkb:HIBBJ46(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834085|imex:IM-21659-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006306.2|refseq:NP_001304765.1|dip:DIP-52782N|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q3KNV8|uniprotkb:Q3KNV8(identity)|entrezgene/locuslink:10336(identity)|ddbj/embl/genbank:BC107061(identity) ensembl:ENSG00000155959(gene)|ensembl:ENST00000286428(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006457"(protein folding)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR016655(Prefoldin, subunit 3)|mint:P61758|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957|refseq:NP_003363.1|refseq:NP_001290472.1|refseq:NP_001290474.1|dip:DIP-46479N|refseq:NP_001290473.1|uniprotkb:P61758(identity)|entrezgene/locuslink:7411(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606 rogid:wHq+HRvhqfKwOaKtONGJdfETQxo9606 intact-crc:3D0D4BE40CF378A6|rigid:8jKFzcATWFD0WHYfnkTlUXRq8No false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KNV8 uniprotkb:O15212 intact:EBI-2339807|uniprotkb:O15262|uniprotkb:D3DVN1|ensembl:ENSP00000354724|ensembl:ENSP00000420489 intact:EBI-356973|ensembl:ENSP00000363734|ensembl:ENSP00000363735|ensembl:ENSP00000363738|ensembl:ENSP00000372694|ensembl:ENSP00000378563|ensembl:ENSP00000382314|ensembl:ENSP00000382316|ensembl:ENSP00000395462|ensembl:ENSP00000398171|ensembl:ENSP00000400152|ensembl:ENSP00000402212|ensembl:ENSP00000402553|ensembl:ENSP00000403771|ensembl:ENSP00000404773|ensembl:ENSP00000412319|ensembl:ENSP00000415678|ensembl:ENSP00000447540|ensembl:ENSP00000448607|ensembl:ENSP00000448784|ensembl:ENSP00000449925 psi-mi:pcgf3_human(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym) psi-mi:pfd6_human(display_long)|uniprotkb:PFDN6(gene name)|psi-mi:PFDN6(display_short)|uniprotkb:HKE2(gene name synonym)|uniprotkb:PFD6(gene name synonym)|uniprotkb:Protein Ke2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834085|imex:IM-21659-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006306.2|refseq:NP_001304765.1|dip:DIP-52782N|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q3KNV8|uniprotkb:Q3KNV8(identity)|entrezgene/locuslink:10336(identity)|ddbj/embl/genbank:BC107061(identity) refseq:NP_001172110.1|refseq:NP_055075.1|refseq:NP_001252524.1|refseq:NP_001252525.1|dip:DIP-50304N|ensembl:ENSG00000204220(gene)|ensembl:ENSG00000206283(gene)|ensembl:ENSG00000224782(gene)|ensembl:ENSG00000235692(gene)|ensembl:ENSG00000237335(gene)|ensembl:ENST00000374606(transcript)|ensembl:ENST00000374607(transcript)|ensembl:ENST00000374610(transcript)|ensembl:ENST00000383207(transcript)|ensembl:ENST00000395131(transcript)|ensembl:ENST00000399383(transcript)|ensembl:ENST00000399385(transcript)|ensembl:ENST00000412289(transcript)|ensembl:ENST00000425878(transcript)|ensembl:ENST00000431830(transcript)|ensembl:ENST00000432391(transcript)|ensembl:ENST00000442285(transcript)|ensembl:ENST00000445559(transcript)|ensembl:ENST00000448594(transcript)|ensembl:ENST00000451970(transcript)|ensembl:ENST00000452658(transcript)|ensembl:ENST00000547641(transcript)|ensembl:ENST00000547952(transcript)|ensembl:ENST00000548040(transcript)|ensembl:ENST00000552711(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|mint:O15212|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957|uniprotkb:O15212(identity)|entrezgene/locuslink:10471(identity) psi-mi:"MI:0469"(intact) - crc64:8F138EAAE512A312 figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606 rogid:t7Z68vuvmprxLIGDh4JhqCGvX+A9606 intact-crc:3D0D4BE40CF378A6|rigid:8jKFzcATWFD0WHYfnkTlUXRq8No false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KNV8 uniprotkb:P68400 intact:EBI-2339807|uniprotkb:O15262|uniprotkb:D3DVN1|ensembl:ENSP00000354724|ensembl:ENSP00000420489 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 psi-mi:pcgf3_human(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym) psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834085|imex:IM-21659-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006306.2|refseq:NP_001304765.1|dip:DIP-52782N|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q3KNV8|uniprotkb:Q3KNV8(identity)|entrezgene/locuslink:10336(identity)|ddbj/embl/genbank:BC107061(identity) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N|uniprotkb:P68400(identity)|entrezgene/locuslink:1457(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 intact-crc:3D0D4BE40CF378A6|rigid:8jKFzcATWFD0WHYfnkTlUXRq8No false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KNV8 uniprotkb:Q9BQE3 intact:EBI-2339807|uniprotkb:O15262|uniprotkb:D3DVN1|ensembl:ENSP00000354724|ensembl:ENSP00000420489 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:pcgf3_human(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834085|imex:IM-21659-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006306.2|refseq:NP_001304765.1|dip:DIP-52782N|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q3KNV8|uniprotkb:Q3KNV8(identity)|entrezgene/locuslink:10336(identity)|ddbj/embl/genbank:BC107061(identity) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1|uniprotkb:Q9BQE3(identity)|entrezgene/locuslink:84790(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:3D0D4BE40CF378A6|rigid:8jKFzcATWFD0WHYfnkTlUXRq8No false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KNV8 uniprotkb:Q9HAH7 intact:EBI-2339807|uniprotkb:O15262|uniprotkb:D3DVN1|ensembl:ENSP00000354724|ensembl:ENSP00000420489 intact:EBI-2847800|uniprotkb:Q9H9X4|uniprotkb:Q96CI9|uniprotkb:B4DP86|ensembl:ENSP00000287468 psi-mi:pcgf3_human(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym) psi-mi:fbrs_human(display_long)|uniprotkb:FBRS(gene name)|psi-mi:FBRS(display_short)|uniprotkb:FBS(gene name synonym)|uniprotkb:FBS1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834085|imex:IM-21659-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006306.2|refseq:NP_001304765.1|dip:DIP-52782N|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q3KNV8|uniprotkb:Q3KNV8(identity)|entrezgene/locuslink:10336(identity)|ddbj/embl/genbank:BC107061(identity) refseq:NP_001098549.2|dip:DIP-61357N|ensembl:ENSG00000156860(gene)|ensembl:ENST00000287468(transcript)|interpro:IPR023246|mint:Q9HAH7|uniprotkb:Q9HAH7(identity)|entrezgene/locuslink:64319(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606 rogid:n1zkWAYdgwY+t7CFWg5RKO1VSfE9606 intact-crc:3D0D4BE40CF378A6|rigid:8jKFzcATWFD0WHYfnkTlUXRq8No false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KNV8 uniprotkb:Q9NQP4 intact:EBI-2339807|uniprotkb:O15262|uniprotkb:D3DVN1|ensembl:ENSP00000354724|ensembl:ENSP00000420489 intact:EBI-357021|uniprotkb:Q5TD11|uniprotkb:Q92779|ensembl:ENSP00000360473 psi-mi:pcgf3_human(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym) psi-mi:pfd4_human(display_long)|uniprotkb:PFDN4(gene name)|psi-mi:PFDN4(display_short)|uniprotkb:PFD4(gene name synonym)|uniprotkb:Protein C-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834085|imex:IM-21659-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006306.2|refseq:NP_001304765.1|dip:DIP-52782N|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q3KNV8|uniprotkb:Q3KNV8(identity)|entrezgene/locuslink:10336(identity)|ddbj/embl/genbank:BC107061(identity) refseq:NP_002614.2|ensembl:ENSG00000101132(gene)|ensembl:ENST00000371419(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|interpro:IPR016661(Prefoldin, subunit 4)|mint:Q9NQP4|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957|uniprotkb:Q9NQP4(identity)|entrezgene/locuslink:5203(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606 rogid:oXbJiHxqcYHrAWGGgzV81ocGt889606 intact-crc:3D0D4BE40CF378A6|rigid:8jKFzcATWFD0WHYfnkTlUXRq8No false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KNV8 uniprotkb:P48643 intact:EBI-2339807|uniprotkb:O15262|uniprotkb:D3DVN1|ensembl:ENSP00000354724|ensembl:ENSP00000420489 intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8 psi-mi:pcgf3_human(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym) psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834085|imex:IM-21659-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006306.2|refseq:NP_001304765.1|dip:DIP-52782N|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q3KNV8|uniprotkb:Q3KNV8(identity)|entrezgene/locuslink:10336(identity)|ddbj/embl/genbank:BC107061(identity) refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N|uniprotkb:P48643(identity)|entrezgene/locuslink:22948(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606 rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606 intact-crc:3D0D4BE40CF378A6|rigid:8jKFzcATWFD0WHYfnkTlUXRq8No false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KNV8 uniprotkb:Q6W2J9 intact:EBI-2339807|uniprotkb:O15262|uniprotkb:D3DVN1|ensembl:ENSP00000354724|ensembl:ENSP00000420489 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 psi-mi:pcgf3_human(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym) psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834085|imex:IM-21659-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006306.2|refseq:NP_001304765.1|dip:DIP-52782N|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q3KNV8|uniprotkb:Q3KNV8(identity)|entrezgene/locuslink:10336(identity)|ddbj/embl/genbank:BC107061(identity) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N|uniprotkb:Q6W2J9(identity)|entrezgene/locuslink:54880(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 intact-crc:3D0D4BE40CF378A6|rigid:8jKFzcATWFD0WHYfnkTlUXRq8No false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KNV8 uniprotkb:P61962 intact:EBI-2339807|uniprotkb:O15262|uniprotkb:D3DVN1|ensembl:ENSP00000354724|ensembl:ENSP00000420489 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 psi-mi:pcgf3_human(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym) psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834085|imex:IM-21659-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006306.2|refseq:NP_001304765.1|dip:DIP-52782N|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q3KNV8|uniprotkb:Q3KNV8(identity)|entrezgene/locuslink:10336(identity)|ddbj/embl/genbank:BC107061(identity) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 intact-crc:3D0D4BE40CF378A6|rigid:8jKFzcATWFD0WHYfnkTlUXRq8No false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KNV8 uniprotkb:P61289 intact:EBI-2339807|uniprotkb:O15262|uniprotkb:D3DVN1|ensembl:ENSP00000354724|ensembl:ENSP00000420489 intact:EBI-355546|uniprotkb:O35563|uniprotkb:P97373|uniprotkb:Q12920|uniprotkb:Q13172|uniprotkb:Q9BQD9|uniprotkb:A8K9A3|ensembl:ENSP00000466794 psi-mi:pcgf3_human(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym) psi-mi:psme3_human(display_long)|uniprotkb:PSME3(gene name)|psi-mi:PSME3(display_short)|uniprotkb:Proteasome activator 28 subunit gamma(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 3(gene name synonym)|uniprotkb:11S regulator complex subunit gamma(gene name synonym)|uniprotkb:Ki nuclear autoantigen(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834085|imex:IM-21659-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006306.2|refseq:NP_001304765.1|dip:DIP-52782N|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q3KNV8|uniprotkb:Q3KNV8(identity)|entrezgene/locuslink:10336(identity)|ddbj/embl/genbank:BC107061(identity) refseq:NP_005780.2|refseq:NP_789839.1|ensembl:ENSG00000131467(gene)|ensembl:ENST00000590720(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:P61289|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|uniprotkb:P61289(identity)|entrezgene/locuslink:10197(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606 rogid:6EQY2Kj3Juf++m4eBDzPWMgbC2k9606 intact-crc:3D0D4BE40CF378A6|rigid:8jKFzcATWFD0WHYfnkTlUXRq8No false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KNV8 uniprotkb:Q99496 intact:EBI-2339807|uniprotkb:O15262|uniprotkb:D3DVN1|ensembl:ENSP00000354724|ensembl:ENSP00000420489 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:pcgf3_human(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834085|imex:IM-21659-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006306.2|refseq:NP_001304765.1|dip:DIP-52782N|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q3KNV8|uniprotkb:Q3KNV8(identity)|entrezgene/locuslink:10336(identity)|ddbj/embl/genbank:BC107061(identity) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|entrezgene/locuslink:6045(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 intact-crc:3D0D4BE40CF378A6|rigid:8jKFzcATWFD0WHYfnkTlUXRq8No false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KNV8 uniprotkb:Q99471 intact:EBI-2339807|uniprotkb:O15262|uniprotkb:D3DVN1|ensembl:ENSP00000354724|ensembl:ENSP00000420489 intact:EBI-357275|ensembl:ENSP00000334188|ensembl:ENSP00000447942|intact:EBI-1047551|uniprotkb:A8K9A8|uniprotkb:Q54AA8|uniprotkb:Q9C083|uniprotkb:Q9C084 psi-mi:pcgf3_human(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym) psi-mi:pfd5_human(display_long)|uniprotkb:c-Myc-binding protein Mm-1(gene name synonym)|uniprotkb:PFDN5(gene name)|psi-mi:PFDN5(display_short)|uniprotkb:MM1(gene name synonym)|uniprotkb:Myc modulator 1(gene name synonym)|uniprotkb:PFD5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834085|imex:IM-21659-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006306.2|refseq:NP_001304765.1|dip:DIP-52782N|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q3KNV8|uniprotkb:Q3KNV8(identity)|entrezgene/locuslink:10336(identity)|ddbj/embl/genbank:BC107061(identity) ensembl:ENSG00000123349(gene)|ensembl:ENST00000334478(transcript)|ensembl:ENST00000551018(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR011599(Prefoldin alpha subunit)|mint:Q99471|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957|refseq:NP_002615.2|refseq:NP_665904.1|dip:DIP-28155N|uniprotkb:Q99471(identity)|entrezgene/locuslink:5204(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606 rogid:Cm4km207qcfDJYRUCIwUxMBT4tE9606 intact-crc:3D0D4BE40CF378A6|rigid:8jKFzcATWFD0WHYfnkTlUXRq8No false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KNV8 uniprotkb:P67870 intact:EBI-2339807|uniprotkb:O15262|uniprotkb:D3DVN1|ensembl:ENSP00000354724|ensembl:ENSP00000420489 intact:EBI-348169|ensembl:ENSP00000365025|ensembl:ENSP00000365026|ensembl:ENSP00000365042|ensembl:ENSP00000372919|ensembl:ENSP00000372925|ensembl:ENSP00000382980|ensembl:ENSP00000390900|ensembl:ENSP00000391038|ensembl:ENSP00000393756|ensembl:ENSP00000394855|ensembl:ENSP00000395275|ensembl:ENSP00000400188|ensembl:ENSP00000407018|ensembl:ENSP00000407379|ensembl:ENSP00000409510|ensembl:ENSP00000410802|ensembl:ENSP00000411322|ensembl:ENSP00000412520|ensembl:ENSP00000413469|ensembl:ENSP00000415237|ensembl:ENSP00000415303|uniprotkb:P07312|uniprotkb:P13862|uniprotkb:Q4VX47|intact:EBI-3866975|uniprotkb:B0UXA9 psi-mi:pcgf3_human(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym) psi-mi:csk2b_human(display_long)|uniprotkb:Phosvitin(gene name synonym)|uniprotkb:Protein G5a(gene name synonym)|uniprotkb:CSNK2B(gene name)|psi-mi:CSNK2B(display_short)|uniprotkb:CK2N(gene name synonym)|uniprotkb:G5A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834085|imex:IM-21659-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006306.2|refseq:NP_001304765.1|dip:DIP-52782N|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q3KNV8|uniprotkb:Q3KNV8(identity)|entrezgene/locuslink:10336(identity)|ddbj/embl/genbank:BC107061(identity) ensembl:ENSG00000204435(gene)|ensembl:ENSG00000230700(gene)|ensembl:ENSG00000206406(gene)|ensembl:ENSG00000232960(gene)|ensembl:ENSG00000224398(gene)|ensembl:ENSG00000224774(gene)|ensembl:ENSG00000228875(gene)|ensembl:ENST00000375882(transcript)|ensembl:ENST00000383427(transcript)|ensembl:ENST00000383433(transcript)|ensembl:ENST00000400110(transcript)|ensembl:ENST00000412802(transcript)|ensembl:ENST00000418230(transcript)|ensembl:ENST00000422567(transcript)|ensembl:ENST00000429633(transcript)|ensembl:ENST00000431476(transcript)|ensembl:ENST00000436169(transcript)|ensembl:ENST00000443673(transcript)|ensembl:ENST00000448596(transcript)|ensembl:ENST00000451917(transcript)|ensembl:ENST00000452985(transcript)|ensembl:ENST00000453234(transcript)|ensembl:ENST00000454382(transcript)|ensembl:ENST00000454511(transcript)|ensembl:ENST00000455161(transcript)|ensembl:ENST00000458330(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0007165"(signal transduction)|ensembl:ENST00000375865(transcript)|ensembl:ENST00000375866(transcript)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016363"(nuclear matrix)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0034622"|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|mint:P67870|rcsb pdb:1DS5|rcsb pdb:1JWH|go:"GO:0008134"(transcription factor binding)|rcsb pdb:1QF8|rcsb pdb:3EED|rcsb pdb:4DGL|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6798695|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:6Q38|refseq:NP_001311.3|refseq:NP_001269314.1|dip:DIP-131N|uniprotkb:P67870(identity)|entrezgene/locuslink:1460(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606 rogid:ZTHJjCqHg2dE7B+WoSU28VSMuPg9606 intact-crc:3D0D4BE40CF378A6|rigid:8jKFzcATWFD0WHYfnkTlUXRq8No false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KNV8 uniprotkb:Q9HCM7 intact:EBI-2339807|uniprotkb:O15262|uniprotkb:D3DVN1|ensembl:ENSP00000354724|ensembl:ENSP00000420489 intact:EBI-6255777|ensembl:ENSP00000396160|uniprotkb:Q86XQ1 psi-mi:pcgf3_human(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym) psi-mi:fbsl_human(display_long)|uniprotkb:FBRSL1(gene name)|psi-mi:FBRSL1(display_short)|uniprotkb:AUTS2L(gene name synonym)|uniprotkb:KIAA1545(gene name synonym)|uniprotkb:XTP9(gene name synonym)|uniprotkb:AUTS2-like protein(gene name synonym)|uniprotkb:HBV X-transactivated gene 9 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834085|imex:IM-21659-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006306.2|refseq:NP_001304765.1|dip:DIP-52782N|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q3KNV8|uniprotkb:Q3KNV8(identity)|entrezgene/locuslink:10336(identity)|ddbj/embl/genbank:BC107061(identity) ensembl:ENSG00000112787(gene)|ensembl:ENST00000434748(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR023246|refseq:NP_001136113.1|uniprotkb:Q9HCM7(identity)|entrezgene/locuslink:57666(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606 rogid:JstP98Bp/L0+GmkLfSdhDHnWmiU9606 intact-crc:3D0D4BE40CF378A6|rigid:8jKFzcATWFD0WHYfnkTlUXRq8No false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KNV8 uniprotkb:Q8IY57 intact:EBI-2339807|uniprotkb:O15262|uniprotkb:D3DVN1|ensembl:ENSP00000354724|ensembl:ENSP00000420489 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 psi-mi:pcgf3_human(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym) psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834085|imex:IM-21659-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006306.2|refseq:NP_001304765.1|dip:DIP-52782N|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q3KNV8|uniprotkb:Q3KNV8(identity)|entrezgene/locuslink:10336(identity)|ddbj/embl/genbank:BC107061(identity) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|entrezgene/locuslink:10138(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 intact-crc:3D0D4BE40CF378A6|rigid:8jKFzcATWFD0WHYfnkTlUXRq8No false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KNV8 uniprotkb:Q06587 intact:EBI-2339807|uniprotkb:O15262|uniprotkb:D3DVN1|ensembl:ENSP00000354724|ensembl:ENSP00000420489 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 psi-mi:pcgf3_human(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym) psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834085|imex:IM-21659-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006306.2|refseq:NP_001304765.1|dip:DIP-52782N|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q3KNV8|uniprotkb:Q3KNV8(identity)|entrezgene/locuslink:10336(identity)|ddbj/embl/genbank:BC107061(identity) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 intact-crc:3D0D4BE40CF378A6|rigid:8jKFzcATWFD0WHYfnkTlUXRq8No false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KNV8 uniprotkb:P50990 intact:EBI-2339807|uniprotkb:O15262|uniprotkb:D3DVN1|ensembl:ENSP00000354724|ensembl:ENSP00000420489 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:pcgf3_human(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834085|imex:IM-21659-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006306.2|refseq:NP_001304765.1|dip:DIP-52782N|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q3KNV8|uniprotkb:Q3KNV8(identity)|entrezgene/locuslink:10336(identity)|ddbj/embl/genbank:BC107061(identity) refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N|uniprotkb:P50990(identity)|entrezgene/locuslink:10694(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/04/15 rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 intact-crc:3D0D4BE40CF378A6|rigid:8jKFzcATWFD0WHYfnkTlUXRq8No false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35226 uniprotkb:O95503 intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851 intact:EBI-3951758|uniprotkb:A8KAH0|uniprotkb:Q96EM5|intact:EBI-28986885|ensembl:ENSP00000384490 psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym) psi-mi:cbx6_human(display_long)|uniprotkb:CBX6(gene name)|psi-mi:CBX6(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834191|imex:IM-21659-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:P35226(identity)|ddbj/embl/genbank:BC011652(identity)|entrezgene/locuslink:648(identity) refseq:NP_001290423.1|ensembl:ENSG00000183741(gene)|refseq:NP_055107.3|ensembl:ENST00000407418(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:O95503|rcsb pdb:3GV6|rcsb pdb:3I90|reactome:R-HSA-2559580|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSP00000384490|dip:DIP-48605N|uniprotkb:O95503(identity)|entrezgene/locuslink:23466(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606 rogid:4iNHCYe1bjb/JcurXP1iGoO/2uA9606 intact-crc:10D74E9950FADD9B|rigid:X1o0hQjC5RbSKtssbn4SQxjHsow false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35226 uniprotkb:O95931 intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851 intact:EBI-3923843|uniprotkb:Q86T17|ensembl:ENSP00000216133 psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym) psi-mi:cbx7_human(display_long)|uniprotkb:CBX7(gene name)|psi-mi:CBX7(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834191|imex:IM-21659-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:P35226(identity)|ddbj/embl/genbank:BC011652(identity)|entrezgene/locuslink:648(identity) refseq:NP_783640.1|ensembl:ENSG00000100307(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|mint:O95931|rcsb pdb:2K1B|rcsb pdb:2L12|rcsb pdb:2L1B|rcsb pdb:3GS2|rcsb pdb:4MN3|rcsb pdb:5EPJ|rcsb pdb:6V2R|ensembl:ENST00000216133(transcript)|dip:DIP-44565N|uniprotkb:O95931(identity)|entrezgene/locuslink:23492(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606 rogid:LDXV9srMj1BL2CaSSot1Bn0/EW49606 intact-crc:10D74E9950FADD9B|rigid:X1o0hQjC5RbSKtssbn4SQxjHsow false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35226 uniprotkb:Q99496 intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834191|imex:IM-21659-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:P35226(identity)|ddbj/embl/genbank:BC011652(identity)|entrezgene/locuslink:648(identity) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|entrezgene/locuslink:6045(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 intact-crc:10D74E9950FADD9B|rigid:X1o0hQjC5RbSKtssbn4SQxjHsow false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35226 uniprotkb:Q8N488 intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym) psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834191|imex:IM-21659-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:P35226(identity)|ddbj/embl/genbank:BC011652(identity)|entrezgene/locuslink:648(identity) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|uniprotkb:Q8N488(identity)|entrezgene/locuslink:23429(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 intact-crc:10D74E9950FADD9B|rigid:X1o0hQjC5RbSKtssbn4SQxjHsow false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35226 uniprotkb:Q8NDX5 intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851 intact:EBI-1223801|uniprotkb:Q5HYF0|uniprotkb:Q6NSG2|uniprotkb:Q8NFT7|uniprotkb:Q8NFZ1|uniprotkb:Q8TBM2|uniprotkb:Q9H971|uniprotkb:Q9H9I4|uniprotkb:A2RRP9|ensembl:ENSP00000420271 psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym) psi-mi:phc3_human(display_long)|uniprotkb:PHC3(gene name)|psi-mi:PHC3(display_short)|uniprotkb:EDR3(gene name synonym)|uniprotkb:PH3(gene name synonym)|uniprotkb:Homolog of polyhomeotic 3(gene name synonym)|uniprotkb:Early development regulatory protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834191|imex:IM-21659-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:P35226(identity)|ddbj/embl/genbank:BC011652(identity)|entrezgene/locuslink:648(identity) refseq:NP_079223.3|refseq:NP_001295045.1|ensembl:ENSP00000420271|ensembl:ENST00000495893|ensembl:ENSP00000420294|ensembl:ENST00000497658|ensembl:ENSP00000420454|ensembl:ENSG00000173889(gene)|ensembl:ENST00000494943(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:Q8NDX5|rcsb pdb:4PZN|rcsb pdb:4PZO|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q8NDX5(identity)|entrezgene/locuslink:80012(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606 rogid:hB1EMs+lCv19uuJ1O7+QiVCUoo89606 intact-crc:10D74E9950FADD9B|rigid:X1o0hQjC5RbSKtssbn4SQxjHsow false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35226 uniprotkb:Q8IXK0 intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851 intact:EBI-713786|uniprotkb:Q8N306|uniprotkb:Q8TAG8|uniprotkb:A1L4Q1|uniprotkb:Q2TAL3|uniprotkb:Q5T0C1|uniprotkb:Q6NUJ6|uniprotkb:Q6ZQR1|uniprotkb:Q96BL4|uniprotkb:Q9Y4Y7|ensembl:ENSP00000257118|uniprotkb:D3DPR2|uniprotkb:A8KA40 psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym) psi-mi:phc2_human(display_long)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:PHC2(gene name)|psi-mi:PHC2(display_short)|uniprotkb:EDR2(gene name synonym)|uniprotkb:PH2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834191|imex:IM-21659-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:P35226(identity)|ddbj/embl/genbank:BC011652(identity)|entrezgene/locuslink:648(identity) interpro:IPR038603|mint:Q8IXK0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR013761(Sterile alpha motif-type)|ensembl:ENSG00000134686(gene)|ensembl:ENST00000257118(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|refseq:NP_004418.2|refseq:NP_932157.1|refseq:XP_016856005.1|refseq:XP_016856006.1|refseq:XP_016856007.1|refseq:XP_005270627.1|dip:DIP-34464N|uniprotkb:Q8IXK0(identity)|entrezgene/locuslink:1912(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606 rogid:7si/KU2tHoxviuCr70ncQERDWmY9606 intact-crc:10D74E9950FADD9B|rigid:X1o0hQjC5RbSKtssbn4SQxjHsow false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35226 uniprotkb:P23396 intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851 intact:EBI-351193|uniprotkb:Q498B5|uniprotkb:Q8NI95|uniprotkb:B2R7N5|ensembl:ENSP00000433821|ensembl:ENSP00000434643|ensembl:ENSP00000436971|uniprotkb:J3KN86 psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym) psi-mi:rs3_human(display_long)|uniprotkb:RPS3(gene name)|psi-mi:RPS3(display_short)|uniprotkb:Small ribosomal subunit protein uS3(gene name synonym)|uniprotkb:OK/SW-cl.26(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834191|imex:IM-21659-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:P35226(identity)|ddbj/embl/genbank:BC011652(identity)|entrezgene/locuslink:648(identity) refseq:NP_000996.2|ensembl:ENSG00000149273(gene)|ensembl:ENST00000524851(transcript)|ensembl:ENST00000527446(transcript)|ensembl:ENST00000531188(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032357"(oxidized purine DNA binding)|go:"GO:0032358"(oxidized pyrimidine DNA binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045738"(negative regulation of DNA repair)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061481"(response to TNF agonist)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902546"(positive regulation of DNA N-glycosylase activity)|go:"GO:1905053"(positive regulation of base-excision repair)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001272"(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001351(Ribosomal protein S3, C-terminal)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR004044(K Homology, type 2)|go:"GO:0070301"(cellular response to hydrogen peroxide)|interpro:IPR005703(Ribosomal protein S3, eukaryotic/archaeal)|go:"GO:0071159"(NF-kappaB complex)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR015946(K homology-like, alpha/beta)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR018280|interpro:IPR036419|mint:P23396|rcsb pdb:1WH9|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|go:"GO:0072686"(mitotic spindle)|go:"GO:0097100"(supercoiled DNA binding)|rcsb pdb:6QZP|go:"GO:0140078"("class I DNA-(apurinic or apyrimidinic site) endonuclease activity")|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|refseq:NP_001243731.1|refseq:NP_001247436.1|refseq:NP_001247435.1|dip:DIP-33177N|uniprotkb:P23396(identity)|entrezgene/locuslink:6188(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606 rogid:fsDW18AMR3YyEEIhMVcngYRWkps9606 intact-crc:10D74E9950FADD9B|rigid:X1o0hQjC5RbSKtssbn4SQxjHsow false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35226 uniprotkb:P78364 intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851 intact:EBI-725403|uniprotkb:Q8WVM3|uniprotkb:Q9BU63|uniprotkb:D3DUV4|ensembl:ENSP00000437659|ensembl:ENSP00000440674 psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym) psi-mi:phc1_human(display_long)|uniprotkb:Early development regulatory protein 1(gene name synonym)|uniprotkb:PHC1(gene name)|psi-mi:PHC1(display_short)|uniprotkb:EDR1(gene name synonym)|uniprotkb:PH1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834191|imex:IM-21659-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:P35226(identity)|ddbj/embl/genbank:BC011652(identity)|entrezgene/locuslink:648(identity) refseq:NP_004417.2|ensembl:ENSG00000111752(gene)|ensembl:ENST00000543824(transcript)|ensembl:ENST00000544916(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:P78364|rcsb pdb:2L8E|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|dip:DIP-44567N|uniprotkb:P78364(identity)|entrezgene/locuslink:1911(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606 rogid:0dDjrgvWcP5Sx8h+qUj7awuM3ko9606 intact-crc:10D74E9950FADD9B|rigid:X1o0hQjC5RbSKtssbn4SQxjHsow false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35226 uniprotkb:Q06587 intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym) psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834191|imex:IM-21659-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:P35226(identity)|ddbj/embl/genbank:BC011652(identity)|entrezgene/locuslink:648(identity) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 intact-crc:10D74E9950FADD9B|rigid:X1o0hQjC5RbSKtssbn4SQxjHsow false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35226 uniprotkb:Q7Z417 intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851 intact:EBI-1210753|intact:EBI-10172018|uniprotkb:A1L3A7|uniprotkb:Q9P2M5|uniprotkb:A1L3A6|ensembl:ENSP00000225388 psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym) psi-mi:nufp2_human(display_long)|uniprotkb:NUFIP2(gene name)|psi-mi:NUFIP2(display_short)|uniprotkb:KIAA1321(gene name synonym)|uniprotkb:PIG1(orf name)|uniprotkb:FMRP-interacting protein 2(gene name synonym)|uniprotkb:82 kDa FMRP-interacting protein(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 1 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834191|imex:IM-21659-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:P35226(identity)|ddbj/embl/genbank:BC011652(identity)|entrezgene/locuslink:648(identity) refseq:NP_065823.1|dip:DIP-29023N|ensembl:ENSG00000108256(gene)|ensembl:ENST00000225388(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR032747|mint:Q7Z417|uniprotkb:Q7Z417(identity)|entrezgene/locuslink:57532(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606 rogid:zdbkRisveP+8g70umfbEPHTnAgk9606 intact-crc:10D74E9950FADD9B|rigid:X1o0hQjC5RbSKtssbn4SQxjHsow false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35226 uniprotkb:Q14781 intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851 intact:EBI-745934|uniprotkb:Q9BTB1|uniprotkb:Q0VDA5|ensembl:ENSP00000308750 psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym) psi-mi:cbx2_human(display_long)|uniprotkb:CBX2(gene name)|psi-mi:CBX2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834191|imex:IM-21659-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:P35226(identity)|ddbj/embl/genbank:BC011652(identity)|entrezgene/locuslink:648(identity) refseq:NP_005180.1|refseq:NP_116036.1|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|go:"GO:0045137"(development of primary sexual characteristics)|interpro:IPR042796|mint:Q14781|rcsb pdb:2D9U|rcsb pdb:3H91|rcsb pdb:5EPK|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSG00000173894(gene)|ensembl:ENST00000310942(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|dip:DIP-48604N|uniprotkb:Q14781(identity)|entrezgene/locuslink:84733(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606 rogid:220eC8UGlmAHHP2WAhZdAveHC3s9606 intact-crc:10D74E9950FADD9B|rigid:X1o0hQjC5RbSKtssbn4SQxjHsow false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35226 uniprotkb:Q9UN30 intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851 intact:EBI-6911404|ensembl:ENSP00000369380|uniprotkb:B2RA08|uniprotkb:Q5H969|uniprotkb:B0FZN6|uniprotkb:Q5H968 psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym) psi-mi:scml1_human(display_long)|uniprotkb:SCML1(gene name)|psi-mi:SCML1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834191|imex:IM-21659-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:P35226(identity)|ddbj/embl/genbank:BC011652(identity)|entrezgene/locuslink:648(identity) ensembl:ENSG00000047634(gene)|ensembl:ENST00000380041(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q9UN30|refseq:XP_016885212.1|refseq:XP_006724571.1|refseq:NP_001032624.1|refseq:NP_001032625.1|refseq:NP_001032629.1|refseq:NP_006737.2|uniprotkb:Q9UN30(identity)|entrezgene/locuslink:6322(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606 rogid:/eJ/2Xuw4P5GzHy1wGRxnYZ4hvY9606 intact-crc:10D74E9950FADD9B|rigid:X1o0hQjC5RbSKtssbn4SQxjHsow false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35226 uniprotkb:O00257 intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym) psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834191|imex:IM-21659-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:P35226(identity)|ddbj/embl/genbank:BC011652(identity)|entrezgene/locuslink:648(identity) refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|uniprotkb:O00257(identity)|entrezgene/locuslink:8535(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 intact-crc:10D74E9950FADD9B|rigid:X1o0hQjC5RbSKtssbn4SQxjHsow false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35226 uniprotkb:Q8IY57 intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym) psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834191|imex:IM-21659-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:P35226(identity)|ddbj/embl/genbank:BC011652(identity)|entrezgene/locuslink:648(identity) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|entrezgene/locuslink:10138(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 intact-crc:10D74E9950FADD9B|rigid:X1o0hQjC5RbSKtssbn4SQxjHsow false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35226 uniprotkb:Q9HC52 intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym) psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834191|imex:IM-21659-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:P35226(identity)|ddbj/embl/genbank:BC011652(identity)|entrezgene/locuslink:648(identity) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N|uniprotkb:Q9HC52(identity)|entrezgene/locuslink:57332(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 intact-crc:10D74E9950FADD9B|rigid:X1o0hQjC5RbSKtssbn4SQxjHsow false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35226 uniprotkb:Q96GA3 intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851 intact:EBI-2558389|uniprotkb:Q96JX8|ensembl:ENSP00000356548 psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym) psi-mi:ltv1_human(display_long)|uniprotkb:LTV1(gene name)|psi-mi:LTV1(display_short)|uniprotkb:C6orf93(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834191|imex:IM-21659-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:P35226(identity)|ddbj/embl/genbank:BC011652(identity)|entrezgene/locuslink:648(identity) refseq:NP_116249.2|ensembl:ENSG00000135521(gene)|ensembl:ENST00000367576(transcript)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR007307(Low temperature viability protein)|mint:Q96GA3|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|reactome:R-HSA-6791226|uniprotkb:Q96GA3(identity)|entrezgene/locuslink:84946(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606 rogid:Csfx8GS5hoclLY1BYki/uUKoSIM9606 intact-crc:10D74E9950FADD9B|rigid:X1o0hQjC5RbSKtssbn4SQxjHsow false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86SE9 uniprotkb:Q9HCM7 intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492 intact:EBI-6255777|ensembl:ENSP00000396160|uniprotkb:Q86XQ1 psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym) psi-mi:fbsl_human(display_long)|uniprotkb:FBRSL1(gene name)|psi-mi:FBRSL1(display_short)|uniprotkb:AUTS2L(gene name synonym)|uniprotkb:KIAA1545(gene name synonym)|uniprotkb:XTP9(gene name synonym)|uniprotkb:AUTS2-like protein(gene name synonym)|uniprotkb:HBV X-transactivated gene 9 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834265|imex:IM-21659-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N|uniprotkb:Q86SE9(identity)|entrezgene/locuslink:84333(identity)|ddbj/embl/genbank:BC051845(identity) ensembl:ENSG00000112787(gene)|ensembl:ENST00000434748(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR023246|refseq:NP_001136113.1|uniprotkb:Q9HCM7(identity)|entrezgene/locuslink:57666(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606 rogid:JstP98Bp/L0+GmkLfSdhDHnWmiU9606 intact-crc:294AB1F96F6EA46E|rigid:W/34f3V1MItiQ/q+NBNZgJdvrbQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86SE9 uniprotkb:Q8WXX7 intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492 intact:EBI-2875359|ensembl:ENSP00000344087|uniprotkb:L7QET3|uniprotkb:L7QF75|uniprotkb:Q5D049|uniprotkb:Q9Y4F2|uniprotkb:A4D1Y9|uniprotkb:Q6PJU5 psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym) psi-mi:auts2_human(display_long)|uniprotkb:AUTS2(gene name)|psi-mi:AUTS2(display_short)|uniprotkb:KIAA0442(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834265|imex:IM-21659-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N|uniprotkb:Q86SE9(identity)|entrezgene/locuslink:84333(identity)|ddbj/embl/genbank:BC051845(identity) ensembl:ENSG00000158321(gene)|ensembl:ENST00000342771(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048675"(axon extension)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0097484"(dendrite extension)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR023246|reactome:R-HSA-8939243|refseq:NP_001120703.1|refseq:NP_001120704.1|refseq:NP_056385.1|dip:DIP-61355N|uniprotkb:Q8WXX7(identity)|entrezgene/locuslink:26053(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606 rogid:8m3VWlXEISEyVwNmlwDFEEKl4Sg9606 intact-crc:294AB1F96F6EA46E|rigid:W/34f3V1MItiQ/q+NBNZgJdvrbQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86SE9 uniprotkb:Q06587 intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym) psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834265|imex:IM-21659-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N|uniprotkb:Q86SE9(identity)|entrezgene/locuslink:84333(identity)|ddbj/embl/genbank:BC051845(identity) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 intact-crc:294AB1F96F6EA46E|rigid:W/34f3V1MItiQ/q+NBNZgJdvrbQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86SE9 uniprotkb:P40227 intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492 intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2 psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym) psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834265|imex:IM-21659-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N|uniprotkb:Q86SE9(identity)|entrezgene/locuslink:84333(identity)|ddbj/embl/genbank:BC051845(identity) refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N|uniprotkb:P40227(identity)|entrezgene/locuslink:908(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606 rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606 intact-crc:294AB1F96F6EA46E|rigid:W/34f3V1MItiQ/q+NBNZgJdvrbQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86SE9 uniprotkb:P48643 intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492 intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8 psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym) psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834265|imex:IM-21659-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N|uniprotkb:Q86SE9(identity)|entrezgene/locuslink:84333(identity)|ddbj/embl/genbank:BC051845(identity) refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N|uniprotkb:P48643(identity)|entrezgene/locuslink:22948(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606 rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606 intact-crc:294AB1F96F6EA46E|rigid:W/34f3V1MItiQ/q+NBNZgJdvrbQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86SE9 uniprotkb:P61962 intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym) psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834265|imex:IM-21659-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N|uniprotkb:Q86SE9(identity)|entrezgene/locuslink:84333(identity)|ddbj/embl/genbank:BC051845(identity) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 intact-crc:294AB1F96F6EA46E|rigid:W/34f3V1MItiQ/q+NBNZgJdvrbQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86SE9 uniprotkb:Q99832 intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492 intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091 psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym) psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834265|imex:IM-21659-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N|uniprotkb:Q86SE9(identity)|entrezgene/locuslink:84333(identity)|ddbj/embl/genbank:BC051845(identity) dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|uniprotkb:Q99832(identity)|entrezgene/locuslink:10574(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606 rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606 intact-crc:294AB1F96F6EA46E|rigid:W/34f3V1MItiQ/q+NBNZgJdvrbQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86SE9 uniprotkb:P67870 intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492 intact:EBI-348169|ensembl:ENSP00000365025|ensembl:ENSP00000365026|ensembl:ENSP00000365042|ensembl:ENSP00000372919|ensembl:ENSP00000372925|ensembl:ENSP00000382980|ensembl:ENSP00000390900|ensembl:ENSP00000391038|ensembl:ENSP00000393756|ensembl:ENSP00000394855|ensembl:ENSP00000395275|ensembl:ENSP00000400188|ensembl:ENSP00000407018|ensembl:ENSP00000407379|ensembl:ENSP00000409510|ensembl:ENSP00000410802|ensembl:ENSP00000411322|ensembl:ENSP00000412520|ensembl:ENSP00000413469|ensembl:ENSP00000415237|ensembl:ENSP00000415303|uniprotkb:P07312|uniprotkb:P13862|uniprotkb:Q4VX47|intact:EBI-3866975|uniprotkb:B0UXA9 psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym) psi-mi:csk2b_human(display_long)|uniprotkb:Phosvitin(gene name synonym)|uniprotkb:Protein G5a(gene name synonym)|uniprotkb:CSNK2B(gene name)|psi-mi:CSNK2B(display_short)|uniprotkb:CK2N(gene name synonym)|uniprotkb:G5A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834265|imex:IM-21659-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N|uniprotkb:Q86SE9(identity)|entrezgene/locuslink:84333(identity)|ddbj/embl/genbank:BC051845(identity) ensembl:ENSG00000204435(gene)|ensembl:ENSG00000230700(gene)|ensembl:ENSG00000206406(gene)|ensembl:ENSG00000232960(gene)|ensembl:ENSG00000224398(gene)|ensembl:ENSG00000224774(gene)|ensembl:ENSG00000228875(gene)|ensembl:ENST00000375882(transcript)|ensembl:ENST00000383427(transcript)|ensembl:ENST00000383433(transcript)|ensembl:ENST00000400110(transcript)|ensembl:ENST00000412802(transcript)|ensembl:ENST00000418230(transcript)|ensembl:ENST00000422567(transcript)|ensembl:ENST00000429633(transcript)|ensembl:ENST00000431476(transcript)|ensembl:ENST00000436169(transcript)|ensembl:ENST00000443673(transcript)|ensembl:ENST00000448596(transcript)|ensembl:ENST00000451917(transcript)|ensembl:ENST00000452985(transcript)|ensembl:ENST00000453234(transcript)|ensembl:ENST00000454382(transcript)|ensembl:ENST00000454511(transcript)|ensembl:ENST00000455161(transcript)|ensembl:ENST00000458330(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0007165"(signal transduction)|ensembl:ENST00000375865(transcript)|ensembl:ENST00000375866(transcript)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016363"(nuclear matrix)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0034622"|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|mint:P67870|rcsb pdb:1DS5|rcsb pdb:1JWH|go:"GO:0008134"(transcription factor binding)|rcsb pdb:1QF8|rcsb pdb:3EED|rcsb pdb:4DGL|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6798695|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:6Q38|refseq:NP_001311.3|refseq:NP_001269314.1|dip:DIP-131N|uniprotkb:P67870(identity)|entrezgene/locuslink:1460(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606 rogid:ZTHJjCqHg2dE7B+WoSU28VSMuPg9606 intact-crc:294AB1F96F6EA46E|rigid:W/34f3V1MItiQ/q+NBNZgJdvrbQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86SE9 uniprotkb:P19784 intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492 intact:EBI-347451|ensembl:ENSP00000262506 psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym) psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834265|imex:IM-21659-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N|uniprotkb:Q86SE9(identity)|entrezgene/locuslink:84333(identity)|ddbj/embl/genbank:BC051845(identity) refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|uniprotkb:P19784(identity)|entrezgene/locuslink:1459(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 intact-crc:294AB1F96F6EA46E|rigid:W/34f3V1MItiQ/q+NBNZgJdvrbQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86SE9 uniprotkb:Q5H9F3 intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492 intact:EBI-8833946|uniprotkb:Q5H9F4|uniprotkb:Q9Y528|uniprotkb:Q8TEN3|uniprotkb:B5MDQ8|uniprotkb:Q6ZVE0|uniprotkb:Q5H9F2|ensembl:ENSP00000218147|ensembl:ENSP00000437775 psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym) psi-mi:bcorl_human(display_long)|uniprotkb:BCORL1(gene name)|psi-mi:BCORL1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834265|imex:IM-21659-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N|uniprotkb:Q86SE9(identity)|entrezgene/locuslink:84333(identity)|ddbj/embl/genbank:BC051845(identity) ensembl:ENSP00000218147|ensembl:ENSP00000437775|refseq:NP_068765.3|dip:DIP-60148N|ensembl:ENSG00000085185(gene)|ensembl:ENST00000218147(transcript)|ensembl:ENST00000540052(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q5H9F3|rcsb pdb:4HPM|rcsb pdb:5JH5|uniprotkb:Q5H9F3(identity)|entrezgene/locuslink:63035(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606 rogid:uQdpjjO3QnnX19nR1Ky76HjCdhw9606 intact-crc:294AB1F96F6EA46E|rigid:W/34f3V1MItiQ/q+NBNZgJdvrbQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86SE9 uniprotkb:P68400 intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym) psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834265|imex:IM-21659-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N|uniprotkb:Q86SE9(identity)|entrezgene/locuslink:84333(identity)|ddbj/embl/genbank:BC051845(identity) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N|uniprotkb:P68400(identity)|entrezgene/locuslink:1457(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 intact-crc:294AB1F96F6EA46E|rigid:W/34f3V1MItiQ/q+NBNZgJdvrbQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86SE9 uniprotkb:P50991 intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492 intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958 psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym) psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834265|imex:IM-21659-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N|uniprotkb:Q86SE9(identity)|entrezgene/locuslink:84333(identity)|ddbj/embl/genbank:BC051845(identity) refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998|uniprotkb:P50991(identity)|entrezgene/locuslink:10575(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606 rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606 intact-crc:294AB1F96F6EA46E|rigid:W/34f3V1MItiQ/q+NBNZgJdvrbQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86SE9 uniprotkb:P47929 intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492 intact:EBI-357504|ensembl:ENSP00000313571|ensembl:ENSP00000367891|ensembl:ENSP00000489395|ensembl:ENSP00000489582|uniprotkb:Q6IB87 psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym) psi-mi:leg7_human(display_long)|uniprotkb:LGALS7(gene name)|psi-mi:LGALS7(display_short)|uniprotkb:PIG1(gene name synonym)|uniprotkb:HKL-14(gene name synonym)|uniprotkb:PI7(gene name synonym)|uniprotkb:p53-induced gene 1 protein(gene name synonym)|uniprotkb:LGALS7B(gene name)|psi-mi:LGALS7B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834265|imex:IM-21659-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N|uniprotkb:Q86SE9(identity)|entrezgene/locuslink:84333(identity)|ddbj/embl/genbank:BC051845(identity) ensembl:ENSG00000178934(gene)|ensembl:ENSG00000205076(gene)|ensembl:ENSG00000282902(gene)|ensembl:ENSG00000283082(gene)|ensembl:ENST00000314980(transcript)|ensembl:ENST00000378626(transcript)|ensembl:ENST00000634448(transcript)|ensembl:ENST00000634800(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016936"(galactoside binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000562"(negative regulation of CD4-positive, alpha-beta T cell proliferation)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030640|interpro:IPR044156|mint:P47929|rcsb pdb:1BKZ|rcsb pdb:2GAL|rcsb pdb:3GAL|rcsb pdb:3ZXE|rcsb pdb:3ZXF|rcsb pdb:4GAL|rcsb pdb:4UW3|rcsb pdb:4UW4|rcsb pdb:4UW5|rcsb pdb:4UW6|rcsb pdb:4XBQ|rcsb pdb:4Y26|rcsb pdb:5GAL|rcsb pdb:5H9Q|rcsb pdb:5H9S|refseq:NP_001035972.1|refseq:NP_002298.1|uniprotkb:P47929(identity)|entrezgene/locuslink:653499(identity)|entrezgene/locuslink:3963(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606 rogid:TIAlvVZ7rOYqTAGrYAFbJY231gc9606 intact-crc:294AB1F96F6EA46E|rigid:W/34f3V1MItiQ/q+NBNZgJdvrbQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86SE9 uniprotkb:P01857 intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492 intact:EBI-356114|ensembl:ENSP00000374991|ensembl:ENSP00000488387 psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym) psi-mi:ighg1_human(display_long)|uniprotkb:IGHG1(gene name)|psi-mi:IGHG1(display_short)|uniprotkb:Ig gamma-1 chain C region(gene name synonym)|uniprotkb:Ig gamma-1 chain C region EU(gene name synonym)|uniprotkb:Ig gamma-1 chain C region KOL(gene name synonym)|uniprotkb:Ig gamma-1 chain C region NIE(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834265|imex:IM-21659-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N|uniprotkb:Q86SE9(identity)|entrezgene/locuslink:84333(identity)|ddbj/embl/genbank:BC051845(identity) ensembl:ENSG00000211896(gene)|ensembl:ENSG00000277633(gene)|ensembl:ENST00000390549(transcript)|ensembl:ENST00000631466(transcript)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:P01857|rcsb pdb:1AJ7|rcsb pdb:1AQK|rcsb pdb:1AXS|rcsb pdb:1BEY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:1DN2|rcsb pdb:1E4K|rcsb pdb:1FC1|rcsb pdb:1FC2|rcsb pdb:1FCC|rcsb pdb:1GAF|rcsb pdb:1H3T|rcsb pdb:1H3U|rcsb pdb:1H3V|rcsb pdb:1H3W|rcsb pdb:1H3X|rcsb pdb:1H3Y|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:1L6X|rcsb pdb:1N7M|rcsb pdb:1OQO|rcsb pdb:1OQX|rcsb pdb:1PG7|rcsb pdb:1T83|rcsb pdb:1T89|rcsb pdb:1VGE|rcsb pdb:2DTS|rcsb pdb:2GJ7|rcsb pdb:2I5Y|rcsb pdb:2IWG|rcsb pdb:2J6E|rcsb pdb:2JB5|rcsb pdb:2JB6|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2OSL|rcsb pdb:2QAD|rcsb pdb:2QL1|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QR0|rcsb pdb:2R56|rcsb pdb:2RCS|rcsb pdb:2VXQ|rcsb pdb:2WAH|rcsb pdb:3AGV|rcsb pdb:3AVE|rcsb pdb:3AY4|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BKY|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3C2S|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D0V|rcsb pdb:3D6G|rcsb pdb:3D85|rcsb pdb:3DJ9|rcsb pdb:3DNK|rcsb pdb:3DO3|rcsb pdb:3DRO|rcsb pdb:3DRQ|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3FJT|rcsb pdb:3MCL|rcsb pdb:3O11|rcsb pdb:3RY6|rcsb pdb:3S7G|rcsb pdb:3SGJ|rcsb pdb:3SGK|rcsb pdb:3TV3|rcsb pdb:3TWC|rcsb pdb:3TYG|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3V7M|rcsb pdb:3V8C|rcsb pdb:3V95|rcsb pdb:3WJJ|rcsb pdb:1I7Z|rcsb pdb:3WJL|rcsb pdb:3WN5|rcsb pdb:4ACP|rcsb pdb:4B7I|rcsb pdb:4BM7|rcsb pdb:4BSV|rcsb pdb:4BSW|rcsb pdb:4BYH|rcsb pdb:4CDH|rcsb pdb:4D9Q|rcsb pdb:4D9R|rcsb pdb:4DAG|rcsb pdb:4DZ8|rcsb pdb:4EOW|rcsb pdb:4HIX|rcsb pdb:4J12|rcsb pdb:4KU1|rcsb pdb:4LLD|rcsb pdb:4LLM|rcsb pdb:4LLQ|rcsb pdb:4N0U|rcsb pdb:4NQS|rcsb pdb:4NQT|rcsb pdb:4NQU|rcsb pdb:4NWT|rcsb pdb:4NWU|rcsb pdb:4O4Y|rcsb pdb:4O51|rcsb pdb:4Q6Y|rcsb pdb:4Q74|rcsb pdb:4Q7D|rcsb pdb:3WKN|rcsb pdb:4W4N|rcsb pdb:4W4O|rcsb pdb:4WI2|rcsb pdb:4WI3|rcsb pdb:4WI4|rcsb pdb:4WI5|rcsb pdb:4WI6|rcsb pdb:4WI7|rcsb pdb:4WI8|rcsb pdb:4WI9|rcsb pdb:4X4M|rcsb pdb:4X98|rcsb pdb:4X99|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XXD|rcsb pdb:4ZNE|rcsb pdb:5BW7|rcsb pdb:5D4Q|rcsb pdb:5D6D|rcsb pdb:5DI8|rcsb pdb:5DJ0|rcsb pdb:5DJ2|rcsb pdb:5DJ6|rcsb pdb:5DJ8|rcsb pdb:5DJA|rcsb pdb:5DJC|rcsb pdb:5DJD|rcsb pdb:5DJX|rcsb pdb:5DJY|rcsb pdb:5DJZ|rcsb pdb:5DK0|rcsb pdb:5DK2|rcsb pdb:5DVK|rcsb pdb:5DVL|rcsb pdb:5DVM|rcsb pdb:5DVN|rcsb pdb:5DVO|rcsb pdb:5GSQ|rcsb pdb:5HSF|rcsb pdb:5HY9|rcsb pdb:5HYE|rcsb pdb:5HYF|rcsb pdb:5HYI|rcsb pdb:5IQ7|rcsb pdb:5IQ9|rcsb pdb:5IW3|rcsb pdb:5IW6|rcsb pdb:5JIH|rcsb pdb:5JII|rcsb pdb:5JIK|rcsb pdb:5K33|rcsb pdb:5K64|rcsb pdb:5K65|rcsb pdb:5K8D|rcsb pdb:5KWG|rcsb pdb:5M3V|rcsb pdb:5TPS|rcsb pdb:5U4Y|rcsb pdb:5U52|rcsb pdb:5U66|rcsb pdb:5V43|rcsb pdb:5V4E|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6DE7|rcsb pdb:6F2Z|rcsb pdb:6G1E|rcsb pdb:6N35|rcsb pdb:6YT7|rcsb pdb:7KWO|reactome:R-HSA-166663|rcsb pdb:4XNZ|reactome:R-HSA-173623|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-6785807|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|dip:DIP-29187N|uniprotkb:P01857(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606 rogid:1YK8rrTDnOYYKW5wHI48/rYlr5o9606 intact-crc:294AB1F96F6EA46E|rigid:W/34f3V1MItiQ/q+NBNZgJdvrbQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86SE9 uniprotkb:P17987 intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492 intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334 psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym) psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834265|imex:IM-21659-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N|uniprotkb:Q86SE9(identity)|entrezgene/locuslink:84333(identity)|ddbj/embl/genbank:BC051845(identity) refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N|uniprotkb:P17987(identity)|entrezgene/locuslink:6950(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606 rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606 intact-crc:294AB1F96F6EA46E|rigid:W/34f3V1MItiQ/q+NBNZgJdvrbQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86SE9 uniprotkb:P31151 intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492 intact:EBI-357520|uniprotkb:Q6FGE3|uniprotkb:Q5SY67|uniprotkb:Q9H1E2|ensembl:ENSP00000357711|ensembl:ENSP00000357712 psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym) psi-mi:s10a7_human(display_long)|uniprotkb:S100A7(gene name)|psi-mi:S100A7(display_short)|uniprotkb:PSOR1(gene name synonym)|uniprotkb:S100A7C(gene name synonym)|uniprotkb:S100 calcium-binding protein A7(gene name synonym)|uniprotkb:Psoriasin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834265|imex:IM-21659-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N|uniprotkb:Q86SE9(identity)|entrezgene/locuslink:84333(identity)|ddbj/embl/genbank:BC051845(identity) ensembl:ENSG00000143556(gene)|ensembl:ENST00000368722(transcript)|ensembl:ENST00000368723(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001525"(angiogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008544"(epidermis development)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045087"(innate immune response)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051238"(sequestering of metal ion)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071624"(positive regulation of granulocyte chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028477|interpro:IPR034325|mint:P31151|rcsb pdb:1PSR|rcsb pdb:2PSR|rcsb pdb:2WND|rcsb pdb:2WOR|rcsb pdb:2WOS|rcsb pdb:3PSR|rcsb pdb:4AQJ|reactome:R-HSA-6798695|reactome:R-HSA-6799990|refseq:NP_002954.2|uniprotkb:P31151(identity)|entrezgene/locuslink:6278(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606 rogid:/v8+XQ7rCMTYzq9k/KqjcSm/G0A9606 intact-crc:294AB1F96F6EA46E|rigid:W/34f3V1MItiQ/q+NBNZgJdvrbQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86SE9 uniprotkb:Q9HAH7 intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492 intact:EBI-2847800|uniprotkb:Q9H9X4|uniprotkb:Q96CI9|uniprotkb:B4DP86|ensembl:ENSP00000287468 psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym) psi-mi:fbrs_human(display_long)|uniprotkb:FBRS(gene name)|psi-mi:FBRS(display_short)|uniprotkb:FBS(gene name synonym)|uniprotkb:FBS1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834265|imex:IM-21659-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N|uniprotkb:Q86SE9(identity)|entrezgene/locuslink:84333(identity)|ddbj/embl/genbank:BC051845(identity) refseq:NP_001098549.2|dip:DIP-61357N|ensembl:ENSG00000156860(gene)|ensembl:ENST00000287468(transcript)|interpro:IPR023246|mint:Q9HAH7|uniprotkb:Q9HAH7(identity)|entrezgene/locuslink:64319(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606 rogid:n1zkWAYdgwY+t7CFWg5RKO1VSfE9606 intact-crc:294AB1F96F6EA46E|rigid:W/34f3V1MItiQ/q+NBNZgJdvrbQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86SE9 uniprotkb:Q99496 intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834265|imex:IM-21659-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N|uniprotkb:Q86SE9(identity)|entrezgene/locuslink:84333(identity)|ddbj/embl/genbank:BC051845(identity) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|entrezgene/locuslink:6045(identity)|uniprotkb:Q99496(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 intact-crc:294AB1F96F6EA46E|rigid:W/34f3V1MItiQ/q+NBNZgJdvrbQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86SE9 uniprotkb:Q8IY57 intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym) psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834265|imex:IM-21659-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N|uniprotkb:Q86SE9(identity)|entrezgene/locuslink:84333(identity)|ddbj/embl/genbank:BC051845(identity) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|entrezgene/locuslink:10138(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 intact-crc:294AB1F96F6EA46E|rigid:W/34f3V1MItiQ/q+NBNZgJdvrbQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86SE9 uniprotkb:P04792 intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492 intact:EBI-352682|uniprotkb:Q6FI47|uniprotkb:Q96C20|uniprotkb:Q96EI7|uniprotkb:Q9UC34|uniprotkb:Q9UC35|uniprotkb:Q9UC36|uniprotkb:Q9UC31|ensembl:ENSP00000248553|uniprotkb:B2R4N8 psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym) psi-mi:hspb1_human(display_long)|uniprotkb:HSPB1(gene name)|psi-mi:HSPB1(display_short)|uniprotkb:HSP27(gene name synonym)|uniprotkb:HSP28(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Stress-responsive protein 27(gene name synonym)|uniprotkb:Estrogen-regulated 24 kDa protein(gene name synonym)|uniprotkb:28 kDa heat shock protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834265|imex:IM-21659-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N|uniprotkb:Q86SE9(identity)|entrezgene/locuslink:84333(identity)|ddbj/embl/genbank:BC051845(identity) refseq:NP_001531.1|ensembl:ENSG00000106211(gene)|ensembl:ENST00000248553(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038033"(positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P04792|rcsb pdb:2N3J|rcsb pdb:3Q9P|rcsb pdb:3Q9Q|rcsb pdb:4MJH|rcsb pdb:6DV5|rcsb pdb:6GJH|reactome:R-HSA-4420097|reactome:R-HSA-450408|reactome:R-HSA-5687128|reactome:R-HSA-9009391|dip:DIP-412N|uniprotkb:P04792(identity)|entrezgene/locuslink:3315(identity) psi-mi:"MI:0469"(intact) - crc64:1B4DC44A6F6606D5 figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606 rogid:vrDXIdzP30aHSDLHOh2D4x54eJY9606 intact-crc:294AB1F96F6EA46E|rigid:W/34f3V1MItiQ/q+NBNZgJdvrbQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86SE9 uniprotkb:O95274 intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492 intact:EBI-2561547|uniprotkb:Q9UJ74|intact:EBI-28988737|ensembl:ENSP00000244333 psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym) psi-mi:lypd3_human(display_long)|uniprotkb:LYPD3(gene name)|psi-mi:LYPD3(display_short)|uniprotkb:C4.4A(gene name synonym)|uniprotkb:GPI-anchored metastasis-associated protein C4.4A homolog(gene name synonym)|uniprotkb:Matrigel-induced gene C4 protein(gene name synonym)|uniprotkb:UNQ491/PRO1007(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834265|imex:IM-21659-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N|uniprotkb:Q86SE9(identity)|entrezgene/locuslink:84333(identity)|ddbj/embl/genbank:BC051845(identity) refseq:NP_055215.2|ensembl:ENSG00000124466(gene)|ensembl:ENST00000244333(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043236"(laminin binding)|go:"GO:0046658"(anchored component of plasma membrane)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:6IOM|rcsb pdb:6ION|reactome:R-HSA-163125|ensembl:ENSP00000244333|uniprotkb:O95274(identity)|entrezgene/locuslink:27076(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606 rogid:I9OUOsh66rmmCCjSLR3Ctyj+W7U9606 intact-crc:294AB1F96F6EA46E|rigid:W/34f3V1MItiQ/q+NBNZgJdvrbQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86SE9 uniprotkb:Q8N488 intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym) psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834265|imex:IM-21659-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N|uniprotkb:Q86SE9(identity)|entrezgene/locuslink:84333(identity)|ddbj/embl/genbank:BC051845(identity) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|uniprotkb:Q8N488(identity)|entrezgene/locuslink:23429(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 intact-crc:294AB1F96F6EA46E|rigid:W/34f3V1MItiQ/q+NBNZgJdvrbQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86SE9 uniprotkb:P78371 intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492 intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300 psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym) psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834265|imex:IM-21659-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N|uniprotkb:Q86SE9(identity)|entrezgene/locuslink:84333(identity)|ddbj/embl/genbank:BC051845(identity) refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695|uniprotkb:P78371(identity)|entrezgene/locuslink:10576(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606 rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606 intact-crc:294AB1F96F6EA46E|rigid:W/34f3V1MItiQ/q+NBNZgJdvrbQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86SE9 uniprotkb:Q6W2J9 intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym) psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834265|imex:IM-21659-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N|uniprotkb:Q86SE9(identity)|entrezgene/locuslink:84333(identity)|ddbj/embl/genbank:BC051845(identity) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N|uniprotkb:Q6W2J9(identity)|entrezgene/locuslink:54880(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 intact-crc:294AB1F96F6EA46E|rigid:W/34f3V1MItiQ/q+NBNZgJdvrbQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86SE9 uniprotkb:P50990 intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834265|imex:IM-21659-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N|uniprotkb:Q86SE9(identity)|entrezgene/locuslink:84333(identity)|ddbj/embl/genbank:BC051845(identity) refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N|uniprotkb:P50990(identity)|entrezgene/locuslink:10694(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 intact-crc:294AB1F96F6EA46E|rigid:W/34f3V1MItiQ/q+NBNZgJdvrbQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BYE7 uniprotkb:P61244 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834375|imex:IM-21659-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity)|ddbj/embl/genbank:BC010235(identity) refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750|uniprotkb:P61244(identity)|entrezgene/locuslink:4149(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rogid:I5d1d/zT353OsLios95yEITNoWU9606 intact-crc:B2AE305F6812E240|rigid:wv+RgcsleqbXU/SSTuIz2l6HFf0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BYE7 uniprotkb:O60220 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 intact:EBI-1049822|uniprotkb:Q6IRW6|uniprotkb:B2R5A6|ensembl:ENSP00000361993 psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:tim8a_human(display_long)|uniprotkb:Deafness dystonia protein 1(gene name synonym)|uniprotkb:X-linked deafness dystonia protein(gene name synonym)|uniprotkb:TIMM8A(gene name)|psi-mi:TIMM8A(display_short)|uniprotkb:DDP(gene name synonym)|uniprotkb:DDP1(gene name synonym)|uniprotkb:TIM8A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834375|imex:IM-21659-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity)|ddbj/embl/genbank:BC010235(identity) refseq:NP_004076.1|reactome:R-HSA-1268020|ensembl:ENSG00000126953(gene)|ensembl:ENST00000372902(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007399"(nervous system development)|go:"GO:0042802"(identical protein binding)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR035427|interpro:IPR039238|mint:O60220|uniprotkb:O60220(identity)|entrezgene/locuslink:1678(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rogid:v01DxxXFU24eNjL3zVBvqQP9zA49606 intact-crc:B2AE305F6812E240|rigid:wv+RgcsleqbXU/SSTuIz2l6HFf0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BYE7 uniprotkb:Q13185 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834375|imex:IM-21659-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity)|ddbj/embl/genbank:BC010235(identity) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 intact-crc:B2AE305F6812E240|rigid:wv+RgcsleqbXU/SSTuIz2l6HFf0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BYE7 uniprotkb:Q99832 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091 psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834375|imex:IM-21659-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity)|ddbj/embl/genbank:BC010235(identity) dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|uniprotkb:Q99832(identity)|entrezgene/locuslink:10574(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606 intact-crc:B2AE305F6812E240|rigid:wv+RgcsleqbXU/SSTuIz2l6HFf0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BYE7 uniprotkb:Q8IWI9 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 intact:EBI-2815196|uniprotkb:E7ENI0|uniprotkb:F5H7K2|uniprotkb:Q9H9N7|uniprotkb:Q9H8R3|uniprotkb:Q9Y4E9|uniprotkb:Q9UG69|intact:EBI-11143500|intact:EBI-10969960|ensembl:ENSP00000219905|uniprotkb:B9EGR5 psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:mgap_human(display_long)|uniprotkb:MGA(gene name)|psi-mi:MGA(display_short)|uniprotkb:KIAA0518(gene name synonym)|uniprotkb:MAD5(gene name synonym)|uniprotkb:MAX dimerization protein 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834375|imex:IM-21659-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity)|ddbj/embl/genbank:BC010235(identity) refseq:NP_001074010.2|ensembl:ENSP00000219905|ensembl:ENST00000566586|ensembl:ENSP00000456141|ensembl:ENSG00000174197(gene)|ensembl:ENST00000219905(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR018186|interpro:IPR032060|interpro:IPR036638|interpro:IPR036960|interpro:IPR037935|mint:Q8IWI9|reactome:R-HSA-8953750|refseq:NP_001157745.1|dip:DIP-57615N|uniprotkb:Q8IWI9(identity)|entrezgene/locuslink:23269(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rogid:P4lo9EteCvikQQk5kyVkcobitLU9606 intact-crc:B2AE305F6812E240|rigid:wv+RgcsleqbXU/SSTuIz2l6HFf0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BYE7 uniprotkb:Q9HCM7 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 intact:EBI-6255777|ensembl:ENSP00000396160|uniprotkb:Q86XQ1 psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:fbsl_human(display_long)|uniprotkb:FBRSL1(gene name)|psi-mi:FBRSL1(display_short)|uniprotkb:AUTS2L(gene name synonym)|uniprotkb:KIAA1545(gene name synonym)|uniprotkb:XTP9(gene name synonym)|uniprotkb:AUTS2-like protein(gene name synonym)|uniprotkb:HBV X-transactivated gene 9 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834375|imex:IM-21659-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity)|ddbj/embl/genbank:BC010235(identity) ensembl:ENSG00000112787(gene)|ensembl:ENST00000434748(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR023246|refseq:NP_001136113.1|uniprotkb:Q9HCM7(identity)|entrezgene/locuslink:57666(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rogid:JstP98Bp/L0+GmkLfSdhDHnWmiU9606 intact-crc:B2AE305F6812E240|rigid:wv+RgcsleqbXU/SSTuIz2l6HFf0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BYE7 uniprotkb:O75461 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834375|imex:IM-21659-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity)|ddbj/embl/genbank:BC010235(identity) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 intact-crc:B2AE305F6812E240|rigid:wv+RgcsleqbXU/SSTuIz2l6HFf0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BYE7 uniprotkb:Q8WXX7 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 intact:EBI-2875359|ensembl:ENSP00000344087|uniprotkb:L7QET3|uniprotkb:L7QF75|uniprotkb:Q5D049|uniprotkb:Q9Y4F2|uniprotkb:A4D1Y9|uniprotkb:Q6PJU5 psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:auts2_human(display_long)|uniprotkb:AUTS2(gene name)|psi-mi:AUTS2(display_short)|uniprotkb:KIAA0442(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834375|imex:IM-21659-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity)|ddbj/embl/genbank:BC010235(identity) ensembl:ENSG00000158321(gene)|ensembl:ENST00000342771(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048675"(axon extension)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0097484"(dendrite extension)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR023246|reactome:R-HSA-8939243|refseq:NP_001120703.1|refseq:NP_001120704.1|refseq:NP_056385.1|dip:DIP-61355N|uniprotkb:Q8WXX7(identity)|entrezgene/locuslink:26053(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rogid:8m3VWlXEISEyVwNmlwDFEEKl4Sg9606 intact-crc:B2AE305F6812E240|rigid:wv+RgcsleqbXU/SSTuIz2l6HFf0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BYE7 uniprotkb:Q8N488 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834375|imex:IM-21659-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity)|ddbj/embl/genbank:BC010235(identity) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|uniprotkb:Q8N488(identity)|entrezgene/locuslink:23429(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 intact-crc:B2AE305F6812E240|rigid:wv+RgcsleqbXU/SSTuIz2l6HFf0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BYE7 uniprotkb:P49368 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688 psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834375|imex:IM-21659-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity)|ddbj/embl/genbank:BC010235(identity) refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N|uniprotkb:P49368(identity)|entrezgene/locuslink:7203(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606 intact-crc:B2AE305F6812E240|rigid:wv+RgcsleqbXU/SSTuIz2l6HFf0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BYE7 uniprotkb:P78371 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300 psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834375|imex:IM-21659-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity)|ddbj/embl/genbank:BC010235(identity) refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695|uniprotkb:P78371(identity)|entrezgene/locuslink:10576(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606 intact-crc:B2AE305F6812E240|rigid:wv+RgcsleqbXU/SSTuIz2l6HFf0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BYE7 uniprotkb:Q14186 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834375|imex:IM-21659-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity)|ddbj/embl/genbank:BC010235(identity) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|entrezgene/locuslink:7027(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 intact-crc:B2AE305F6812E240|rigid:wv+RgcsleqbXU/SSTuIz2l6HFf0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BYE7 uniprotkb:Q9HAH7 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 intact:EBI-2847800|uniprotkb:Q9H9X4|uniprotkb:Q96CI9|uniprotkb:B4DP86|ensembl:ENSP00000287468 psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:fbrs_human(display_long)|uniprotkb:FBRS(gene name)|psi-mi:FBRS(display_short)|uniprotkb:FBS(gene name synonym)|uniprotkb:FBS1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834375|imex:IM-21659-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity)|ddbj/embl/genbank:BC010235(identity) refseq:NP_001098549.2|dip:DIP-61357N|ensembl:ENSG00000156860(gene)|ensembl:ENST00000287468(transcript)|interpro:IPR023246|mint:Q9HAH7|uniprotkb:Q9HAH7(identity)|entrezgene/locuslink:64319(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rogid:n1zkWAYdgwY+t7CFWg5RKO1VSfE9606 intact-crc:B2AE305F6812E240|rigid:wv+RgcsleqbXU/SSTuIz2l6HFf0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BYE7 uniprotkb:Q92769 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 intact:EBI-301821|uniprotkb:Q5SRI8|uniprotkb:Q5SZ86|uniprotkb:Q8NEH4|uniprotkb:B4DL58|ensembl:ENSP00000430432|uniprotkb:E1P561|uniprotkb:B3KRS5 psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:hdac2_human(display_long)|uniprotkb:HDAC2(gene name)|psi-mi:HDAC2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834375|imex:IM-21659-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity)|ddbj/embl/genbank:BC010235(identity) go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035094"(response to nicotine)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042220"(response to cocaine)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q92769|rcsb pdb:3MAX|rcsb pdb:4LXZ|rcsb pdb:4LY1|rcsb pdb:5IWG|rcsb pdb:5IX0|rcsb pdb:6G3O|rcsb pdb:6WBW|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000196591(gene)|ensembl:ENST00000519065(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|rcsb pdb:6WHN|rcsb pdb:6WHO|rcsb pdb:6WHQ|rcsb pdb:6WHZ|rcsb pdb:6WI3|rcsb pdb:6XDM|rcsb pdb:6XEB|rcsb pdb:6XEC|rcsb pdb:7KBG|rcsb pdb:7KBH|rcsb pdb:7LTG|rcsb pdb:7LTK|rcsb pdb:7LTL|reactome:R-HSA-193670|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9615017|reactome:R-HSA-9619665|reactome:R-HSA-9679191|reactome:R-HSA-983231|rcsb pdb:6WBZ|refseq:NP_001518.3|dip:DIP-24220N|refseq:XP_011534090.1|refseq:XP_016866288.1|uniprotkb:Q92769(identity)|entrezgene/locuslink:3066(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rogid:K4PpGz9E9/TrQZsgvrJuc+uYCn89606 intact-crc:B2AE305F6812E240|rigid:wv+RgcsleqbXU/SSTuIz2l6HFf0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BYE7 uniprotkb:Q06587 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834375|imex:IM-21659-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity)|ddbj/embl/genbank:BC010235(identity) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 intact-crc:B2AE305F6812E240|rigid:wv+RgcsleqbXU/SSTuIz2l6HFf0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BYE7 uniprotkb:Q969R5 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834375|imex:IM-21659-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity)|ddbj/embl/genbank:BC010235(identity) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750|uniprotkb:Q969R5(identity)|entrezgene/locuslink:83746(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 intact-crc:B2AE305F6812E240|rigid:wv+RgcsleqbXU/SSTuIz2l6HFf0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BYE7 uniprotkb:P50990 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834375|imex:IM-21659-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity)|ddbj/embl/genbank:BC010235(identity) refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N|uniprotkb:P50990(identity)|entrezgene/locuslink:10694(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 intact-crc:B2AE305F6812E240|rigid:wv+RgcsleqbXU/SSTuIz2l6HFf0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BYE7 uniprotkb:P50991 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958 psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834375|imex:IM-21659-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity)|ddbj/embl/genbank:BC010235(identity) refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998|uniprotkb:P50991(identity)|entrezgene/locuslink:10575(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606 intact-crc:B2AE305F6812E240|rigid:wv+RgcsleqbXU/SSTuIz2l6HFf0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BYE7 uniprotkb:P17987 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334 psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834375|imex:IM-21659-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity)|ddbj/embl/genbank:BC010235(identity) refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N|uniprotkb:P17987(identity)|entrezgene/locuslink:6950(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606 intact-crc:B2AE305F6812E240|rigid:wv+RgcsleqbXU/SSTuIz2l6HFf0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BYE7 uniprotkb:Q14188 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 intact:EBI-752268|uniprotkb:Q13331|uniprotkb:Q14187|uniprotkb:Q6R754|uniprotkb:Q8WU88|uniprotkb:F8WAI2|uniprotkb:Q9UG28|uniprotkb:D3DNG1|uniprotkb:B7Z8L5|uniprotkb:B7Z8C8|uniprotkb:E9PFC3|ensembl:ENSP00000420616 psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:tfdp2_human(display_long)|uniprotkb:E2F dimerization partner 2(gene name synonym)|uniprotkb:TFDP2(gene name)|psi-mi:TFDP2(display_short)|uniprotkb:DP2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834375|imex:IM-21659-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity)|ddbj/embl/genbank:BC010235(identity) refseq:NP_001171609.1|refseq:NP_001171610.1|refseq:NP_006277.1|refseq:NP_001171612.1|refseq:NP_001171613.1|refseq:NP_001171611.1|refseq:XP_016862580.1|refseq:XP_016862585.1|refseq:XP_016862586.1|refseq:XP_016862587.1|refseq:XP_016862588.1|dip:DIP-294N|ensembl:ENSG00000114126(gene)|ensembl:ENST00000489671(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14188|rcsb pdb:1CF7|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9616222|reactome:R-HSA-9661069|uniprotkb:Q14188(identity)|entrezgene/locuslink:7029(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rogid:Y+N26+kjBjMVwXdL4AEp0Sc1rYY9606 intact-crc:B2AE305F6812E240|rigid:wv+RgcsleqbXU/SSTuIz2l6HFf0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BYE7 uniprotkb:P48643 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8 psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834375|imex:IM-21659-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity)|ddbj/embl/genbank:BC010235(identity) refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N|uniprotkb:P48643(identity)|entrezgene/locuslink:22948(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606 intact-crc:B2AE305F6812E240|rigid:wv+RgcsleqbXU/SSTuIz2l6HFf0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BYE7 uniprotkb:Q8IY57 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834375|imex:IM-21659-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity)|ddbj/embl/genbank:BC010235(identity) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|entrezgene/locuslink:10138(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 intact-crc:B2AE305F6812E240|rigid:wv+RgcsleqbXU/SSTuIz2l6HFf0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BYE7 uniprotkb:Q99496 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834375|imex:IM-21659-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity)|ddbj/embl/genbank:BC010235(identity) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|entrezgene/locuslink:6045(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 intact-crc:B2AE305F6812E240|rigid:wv+RgcsleqbXU/SSTuIz2l6HFf0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BYE7 uniprotkb:P05089 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 intact:EBI-2513844|uniprotkb:Q5JWT6|uniprotkb:Q5JWT5|uniprotkb:Q9BS50|uniprotkb:Q8TE72|uniprotkb:A6NEA0|ensembl:ENSP00000357066 psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:argi1_human(display_long)|uniprotkb:ARG1(gene name)|psi-mi:ARG1(display_short)|uniprotkb:Type I arginase(gene name synonym)|uniprotkb:Liver-type arginase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834375|imex:IM-21659-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity)|ddbj/embl/genbank:BC010235(identity) refseq:NP_000036.2|refseq:NP_001231367.1|ensembl:ENSG00000118520(gene)|ensembl:ENST00000368087(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0001889"(liver development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004053"(arginase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006527"(arginine catabolic process)|go:"GO:0007568"(aging)|go:"GO:0009635"(response to herbicide)|go:"GO:0010042"(response to manganese ion)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010963"|go:"GO:0014075"(response to amine)|go:"GO:0019547"(arginine catabolic process to ornithine)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030324"(lung development)|go:"GO:0032964"(collagen biosynthetic process)|go:"GO:0033189"(response to vitamin A)|go:"GO:0033197"(response to vitamin E)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043200"(response to amino acid)|go:"GO:0045087"(innate immune response)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048678"(response to axon injury)|go:"GO:0051597"(response to methylmercury)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070965"(positive regulation of neutrophil mediated killing of fungus)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071377"(cellular response to glucagon stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:2000552"(negative regulation of T-helper 2 cell cytokine production)|interpro:IPR006035(Ureohydrolase)|interpro:IPR014033(Arginase, subgroup)|go:"GO:0060056"(mammary gland involution)|interpro:IPR020855|interpro:IPR023696|mint:P05089|rcsb pdb:1WVA|rcsb pdb:1WVB|rcsb pdb:2AEB|rcsb pdb:2PHA|rcsb pdb:2PHO|rcsb pdb:2PLL|rcsb pdb:2ZAV|rcsb pdb:3DJ8|rcsb pdb:3E6K|rcsb pdb:3E6V|rcsb pdb:3F80|rcsb pdb:3GMZ|rcsb pdb:3GN0|rcsb pdb:3KV2|rcsb pdb:3LP4|rcsb pdb:3LP7|rcsb pdb:3MFV|rcsb pdb:3MFW|rcsb pdb:3MJL|rcsb pdb:3SJT|rcsb pdb:3SKK|rcsb pdb:3TF3|rcsb pdb:3TH7|rcsb pdb:3THE|rcsb pdb:3THH|rcsb pdb:3THJ|rcsb pdb:4FCI|rcsb pdb:4FCK|rcsb pdb:4GSM|rcsb pdb:4GSV|rcsb pdb:4GSZ|rcsb pdb:4GWC|rcsb pdb:4GWD|rcsb pdb:4HWW|rcsb pdb:4HXQ|rcsb pdb:4IE1|rcsb pdb:6Q92|rcsb pdb:6Q9P|rcsb pdb:6QAF|rcsb pdb:6V7C|rcsb pdb:6V7D|rcsb pdb:6V7E|rcsb pdb:6V7F|reactome:R-HSA-6798695|reactome:R-HSA-70635|uniprotkb:P05089(identity)|entrezgene/locuslink:383(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rogid:b8HHscDekWZdN1S4OxFTA6rjvn89606 intact-crc:B2AE305F6812E240|rigid:wv+RgcsleqbXU/SSTuIz2l6HFf0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BYE7 uniprotkb:Q13263 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 intact:EBI-78139|uniprotkb:O00677|ensembl:ENSP00000253024|uniprotkb:Q7Z632|uniprotkb:Q93040|uniprotkb:Q96IM1 psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:tif1b_human(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834375|imex:IM-21659-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity)|ddbj/embl/genbank:BC010235(identity) ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6QAJ|rcsb pdb:6QU1|reactome:R-HSA-212436|reactome:R-HSA-3899300|reactome:R-HSA-9609690|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q13263|rcsb pdb:1FP0|rcsb pdb:2RO1|rcsb pdb:2YVR|rcsb pdb:6H3A|rcsb pdb:6I9H|refseq:NP_005753.1|dip:DIP-30891N|uniprotkb:Q13263(identity)|entrezgene/locuslink:10155(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606 intact-crc:B2AE305F6812E240|rigid:wv+RgcsleqbXU/SSTuIz2l6HFf0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BYE7 uniprotkb:Q13547 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 intact:EBI-301834|uniprotkb:Q92534|ensembl:ENSP00000362649 psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:hdac1_human(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:RPD3L1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834375|imex:IM-21659-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity)|ddbj/embl/genbank:BC010235(identity) ensembl:ENSG00000116478(gene)|ensembl:ENST00000373548(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007492"(endoderm development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031000"(response to caffeine)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043044"|go:"GO:0019213"(deacetylase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900221"(regulation of amyloid-beta clearance)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q13547|rcsb pdb:1TYI|rcsb pdb:4BKX|rcsb pdb:5ICN|rcsb pdb:6Z2J|rcsb pdb:6Z2K|rcsb pdb:7AO8|rcsb pdb:7AO9|rcsb pdb:7AOA|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-193670|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-3769402|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-4641265|reactome:R-HSA-6804758|reactome:R-HSA-69205|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9022538|reactome:R-HSA-9022692|go:"GO:0017053"(transcription repressor complex)|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9615017|reactome:R-HSA-9679191|reactome:R-HSA-983231|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:NP_004955.2|dip:DIP-24184N|uniprotkb:Q13547(identity)|entrezgene/locuslink:3065(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rogid:RP+yIBWH55NgoPTY1nKXqeJL/xY9606 intact-crc:B2AE305F6812E240|rigid:wv+RgcsleqbXU/SSTuIz2l6HFf0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BYE7 uniprotkb:P40227 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2 psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834375|imex:IM-21659-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity)|ddbj/embl/genbank:BC010235(identity) refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N|uniprotkb:P40227(identity)|entrezgene/locuslink:908(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606 intact-crc:B2AE305F6812E240|rigid:wv+RgcsleqbXU/SSTuIz2l6HFf0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BYE7 uniprotkb:P61962 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834375|imex:IM-21659-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity)|ddbj/embl/genbank:BC010235(identity) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 intact-crc:B2AE305F6812E240|rigid:wv+RgcsleqbXU/SSTuIz2l6HFf0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BYE7 uniprotkb:P83916 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834375|imex:IM-21659-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity)|ddbj/embl/genbank:BC010235(identity) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|entrezgene/locuslink:10951(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 intact-crc:B2AE305F6812E240|rigid:wv+RgcsleqbXU/SSTuIz2l6HFf0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BYE7 uniprotkb:Q9Y5L4 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 intact:EBI-1057344|uniprotkb:P62206|uniprotkb:Q9UHL8|uniprotkb:Q9WTL1|ensembl:ENSP00000215570 psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:tim13_human(display_long)|uniprotkb:TIMM13(gene name)|psi-mi:TIMM13(display_short)|uniprotkb:TIM13B(gene name synonym)|uniprotkb:TIMM13A(gene name synonym)|uniprotkb:TIMM13B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834375|imex:IM-21659-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity)|ddbj/embl/genbank:BC010235(identity) refseq:NP_036590.1|ensembl:ENSG00000099800(gene)|ensembl:ENST00000215570(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042719"(mitochondrial intermembrane space protein transporter complex)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR035427|interpro:IPR039238|mint:Q9Y5L4|reactome:R-HSA-1268020|uniprotkb:Q9Y5L4(identity)|entrezgene/locuslink:26517(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rogid:kFNYBvKwUM0JECXq9FjvYv55JAM9606 intact-crc:B2AE305F6812E240|rigid:wv+RgcsleqbXU/SSTuIz2l6HFf0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BYE7 uniprotkb:P61964 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834375|imex:IM-21659-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity)|ddbj/embl/genbank:BC010235(identity) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|entrezgene/locuslink:11091(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 intact-crc:B2AE305F6812E240|rigid:wv+RgcsleqbXU/SSTuIz2l6HFf0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P78364 uniprotkb:O95503 intact:EBI-725403|uniprotkb:Q8WVM3|uniprotkb:Q9BU63|uniprotkb:D3DUV4|ensembl:ENSP00000437659|ensembl:ENSP00000440674 intact:EBI-3951758|uniprotkb:A8KAH0|uniprotkb:Q96EM5|intact:EBI-28986885|ensembl:ENSP00000384490 psi-mi:phc1_human(display_long)|uniprotkb:Early development regulatory protein 1(gene name synonym)|uniprotkb:PHC1(gene name)|psi-mi:PHC1(display_short)|uniprotkb:EDR1(gene name synonym)|uniprotkb:PH1(gene name synonym) psi-mi:cbx6_human(display_long)|uniprotkb:CBX6(gene name)|psi-mi:CBX6(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834509|imex:IM-21659-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004417.2|ensembl:ENSG00000111752(gene)|ensembl:ENST00000543824(transcript)|ensembl:ENST00000544916(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:P78364|rcsb pdb:2L8E|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|dip:DIP-44567N|uniprotkb:P78364(identity)|entrezgene/locuslink:1911(identity)|ddbj/embl/genbank:BC017748(identity) refseq:NP_001290423.1|ensembl:ENSG00000183741(gene)|refseq:NP_055107.3|ensembl:ENST00000407418(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:O95503|rcsb pdb:3GV6|rcsb pdb:3I90|reactome:R-HSA-2559580|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSP00000384490|dip:DIP-48605N|uniprotkb:O95503(identity)|entrezgene/locuslink:23466(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:0dDjrgvWcP5Sx8h+qUj7awuM3ko9606 rogid:4iNHCYe1bjb/JcurXP1iGoO/2uA9606 intact-crc:13327435383EA37B|rigid:WxmLmu1uyDG3D8+45FVqjzmR97s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P78364 uniprotkb:Q99496 intact:EBI-725403|uniprotkb:Q8WVM3|uniprotkb:Q9BU63|uniprotkb:D3DUV4|ensembl:ENSP00000437659|ensembl:ENSP00000440674 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:phc1_human(display_long)|uniprotkb:Early development regulatory protein 1(gene name synonym)|uniprotkb:PHC1(gene name)|psi-mi:PHC1(display_short)|uniprotkb:EDR1(gene name synonym)|uniprotkb:PH1(gene name synonym) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834509|imex:IM-21659-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004417.2|ensembl:ENSG00000111752(gene)|ensembl:ENST00000543824(transcript)|ensembl:ENST00000544916(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:P78364|rcsb pdb:2L8E|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|dip:DIP-44567N|uniprotkb:P78364(identity)|entrezgene/locuslink:1911(identity)|ddbj/embl/genbank:BC017748(identity) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|entrezgene/locuslink:6045(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:0dDjrgvWcP5Sx8h+qUj7awuM3ko9606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 intact-crc:13327435383EA37B|rigid:WxmLmu1uyDG3D8+45FVqjzmR97s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P78364 uniprotkb:O95931 intact:EBI-725403|uniprotkb:Q8WVM3|uniprotkb:Q9BU63|uniprotkb:D3DUV4|ensembl:ENSP00000437659|ensembl:ENSP00000440674 intact:EBI-3923843|uniprotkb:Q86T17|ensembl:ENSP00000216133 psi-mi:phc1_human(display_long)|uniprotkb:Early development regulatory protein 1(gene name synonym)|uniprotkb:PHC1(gene name)|psi-mi:PHC1(display_short)|uniprotkb:EDR1(gene name synonym)|uniprotkb:PH1(gene name synonym) psi-mi:cbx7_human(display_long)|uniprotkb:CBX7(gene name)|psi-mi:CBX7(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834509|imex:IM-21659-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004417.2|ensembl:ENSG00000111752(gene)|ensembl:ENST00000543824(transcript)|ensembl:ENST00000544916(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:P78364|rcsb pdb:2L8E|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|dip:DIP-44567N|uniprotkb:P78364(identity)|entrezgene/locuslink:1911(identity)|ddbj/embl/genbank:BC017748(identity) refseq:NP_783640.1|ensembl:ENSG00000100307(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|mint:O95931|rcsb pdb:2K1B|rcsb pdb:2L12|rcsb pdb:2L1B|rcsb pdb:3GS2|rcsb pdb:4MN3|rcsb pdb:5EPJ|rcsb pdb:6V2R|ensembl:ENST00000216133(transcript)|dip:DIP-44565N|uniprotkb:O95931(identity)|entrezgene/locuslink:23492(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:0dDjrgvWcP5Sx8h+qUj7awuM3ko9606 rogid:LDXV9srMj1BL2CaSSot1Bn0/EW49606 intact-crc:13327435383EA37B|rigid:WxmLmu1uyDG3D8+45FVqjzmR97s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P78364 uniprotkb:O00257 intact:EBI-725403|uniprotkb:Q8WVM3|uniprotkb:Q9BU63|uniprotkb:D3DUV4|ensembl:ENSP00000437659|ensembl:ENSP00000440674 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 psi-mi:phc1_human(display_long)|uniprotkb:Early development regulatory protein 1(gene name synonym)|uniprotkb:PHC1(gene name)|psi-mi:PHC1(display_short)|uniprotkb:EDR1(gene name synonym)|uniprotkb:PH1(gene name synonym) psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834509|imex:IM-21659-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004417.2|ensembl:ENSG00000111752(gene)|ensembl:ENST00000543824(transcript)|ensembl:ENST00000544916(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:P78364|rcsb pdb:2L8E|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|dip:DIP-44567N|uniprotkb:P78364(identity)|entrezgene/locuslink:1911(identity)|ddbj/embl/genbank:BC017748(identity) refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|uniprotkb:O00257(identity)|entrezgene/locuslink:8535(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:0dDjrgvWcP5Sx8h+qUj7awuM3ko9606 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 intact-crc:13327435383EA37B|rigid:WxmLmu1uyDG3D8+45FVqjzmR97s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P78364 uniprotkb:Q9BQE3 intact:EBI-725403|uniprotkb:Q8WVM3|uniprotkb:Q9BU63|uniprotkb:D3DUV4|ensembl:ENSP00000437659|ensembl:ENSP00000440674 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:phc1_human(display_long)|uniprotkb:Early development regulatory protein 1(gene name synonym)|uniprotkb:PHC1(gene name)|psi-mi:PHC1(display_short)|uniprotkb:EDR1(gene name synonym)|uniprotkb:PH1(gene name synonym) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834509|imex:IM-21659-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004417.2|ensembl:ENSG00000111752(gene)|ensembl:ENST00000543824(transcript)|ensembl:ENST00000544916(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:P78364|rcsb pdb:2L8E|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|dip:DIP-44567N|uniprotkb:P78364(identity)|entrezgene/locuslink:1911(identity)|ddbj/embl/genbank:BC017748(identity) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1|uniprotkb:Q9BQE3(identity)|entrezgene/locuslink:84790(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:0dDjrgvWcP5Sx8h+qUj7awuM3ko9606 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:13327435383EA37B|rigid:WxmLmu1uyDG3D8+45FVqjzmR97s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P78364 uniprotkb:Q9UN30 intact:EBI-725403|uniprotkb:Q8WVM3|uniprotkb:Q9BU63|uniprotkb:D3DUV4|ensembl:ENSP00000437659|ensembl:ENSP00000440674 intact:EBI-6911404|ensembl:ENSP00000369380|uniprotkb:B2RA08|uniprotkb:Q5H969|uniprotkb:B0FZN6|uniprotkb:Q5H968 psi-mi:phc1_human(display_long)|uniprotkb:Early development regulatory protein 1(gene name synonym)|uniprotkb:PHC1(gene name)|psi-mi:PHC1(display_short)|uniprotkb:EDR1(gene name synonym)|uniprotkb:PH1(gene name synonym) psi-mi:scml1_human(display_long)|uniprotkb:SCML1(gene name)|psi-mi:SCML1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834509|imex:IM-21659-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004417.2|ensembl:ENSG00000111752(gene)|ensembl:ENST00000543824(transcript)|ensembl:ENST00000544916(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:P78364|rcsb pdb:2L8E|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|dip:DIP-44567N|uniprotkb:P78364(identity)|entrezgene/locuslink:1911(identity)|ddbj/embl/genbank:BC017748(identity) ensembl:ENSG00000047634(gene)|ensembl:ENST00000380041(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q9UN30|refseq:XP_016885212.1|refseq:XP_006724571.1|refseq:NP_001032624.1|refseq:NP_001032625.1|refseq:NP_001032629.1|refseq:NP_006737.2|uniprotkb:Q9UN30(identity)|entrezgene/locuslink:6322(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:0dDjrgvWcP5Sx8h+qUj7awuM3ko9606 rogid:/eJ/2Xuw4P5GzHy1wGRxnYZ4hvY9606 intact-crc:13327435383EA37B|rigid:WxmLmu1uyDG3D8+45FVqjzmR97s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P78364 uniprotkb:Q06587 intact:EBI-725403|uniprotkb:Q8WVM3|uniprotkb:Q9BU63|uniprotkb:D3DUV4|ensembl:ENSP00000437659|ensembl:ENSP00000440674 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 psi-mi:phc1_human(display_long)|uniprotkb:Early development regulatory protein 1(gene name synonym)|uniprotkb:PHC1(gene name)|psi-mi:PHC1(display_short)|uniprotkb:EDR1(gene name synonym)|uniprotkb:PH1(gene name synonym) psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834509|imex:IM-21659-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004417.2|ensembl:ENSG00000111752(gene)|ensembl:ENST00000543824(transcript)|ensembl:ENST00000544916(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:P78364|rcsb pdb:2L8E|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|dip:DIP-44567N|uniprotkb:P78364(identity)|entrezgene/locuslink:1911(identity)|ddbj/embl/genbank:BC017748(identity) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:0dDjrgvWcP5Sx8h+qUj7awuM3ko9606 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 intact-crc:13327435383EA37B|rigid:WxmLmu1uyDG3D8+45FVqjzmR97s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P78364 uniprotkb:P35226 intact:EBI-725403|uniprotkb:Q8WVM3|uniprotkb:Q9BU63|uniprotkb:D3DUV4|ensembl:ENSP00000437659|ensembl:ENSP00000440674 intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851 psi-mi:phc1_human(display_long)|uniprotkb:Early development regulatory protein 1(gene name synonym)|uniprotkb:PHC1(gene name)|psi-mi:PHC1(display_short)|uniprotkb:EDR1(gene name synonym)|uniprotkb:PH1(gene name synonym) psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834509|imex:IM-21659-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004417.2|ensembl:ENSG00000111752(gene)|ensembl:ENST00000543824(transcript)|ensembl:ENST00000544916(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:P78364|rcsb pdb:2L8E|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|dip:DIP-44567N|uniprotkb:P78364(identity)|entrezgene/locuslink:1911(identity)|ddbj/embl/genbank:BC017748(identity) refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:P35226(identity)|entrezgene/locuslink:100532731(identity)|entrezgene/locuslink:648(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:0dDjrgvWcP5Sx8h+qUj7awuM3ko9606 rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606 intact-crc:13327435383EA37B|rigid:WxmLmu1uyDG3D8+45FVqjzmR97s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P78364 uniprotkb:P35227 intact:EBI-725403|uniprotkb:Q8WVM3|uniprotkb:Q9BU63|uniprotkb:D3DUV4|ensembl:ENSP00000437659|ensembl:ENSP00000440674 intact:EBI-2129767|uniprotkb:A6NGD8|ensembl:ENSP00000478517|ensembl:ENSP00000478970|ensembl:ENSP00000482063|ensembl:ENSP00000482815|ensembl:ENSP00000488868|ensembl:ENSP00000488872 psi-mi:phc1_human(display_long)|uniprotkb:Early development regulatory protein 1(gene name synonym)|uniprotkb:PHC1(gene name)|psi-mi:PHC1(display_short)|uniprotkb:EDR1(gene name synonym)|uniprotkb:PH1(gene name synonym) psi-mi:pcgf2_human(display_long)|uniprotkb:PCGF2(gene name)|psi-mi:PCGF2(display_short)|uniprotkb:MEL18(gene name synonym)|uniprotkb:RNF110(gene name synonym)|uniprotkb:ZNF144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834509|imex:IM-21659-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004417.2|ensembl:ENSG00000111752(gene)|ensembl:ENST00000543824(transcript)|ensembl:ENST00000544916(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:P78364|rcsb pdb:2L8E|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|dip:DIP-44567N|uniprotkb:P78364(identity)|entrezgene/locuslink:1911(identity)|ddbj/embl/genbank:BC017748(identity) refseq:NP_009075.1|refseq:XP_016880505.1|refseq:XP_005257697.1|refseq:XP_005257698.1|refseq:XP_005257699.1|dip:DIP-41880N|ensembl:ENSG00000277258(gene)|ensembl:ENSG00000278644(gene)|ensembl:ENST00000610440(transcript)|ensembl:ENST00000611883(transcript)|ensembl:ENST00000616199(transcript)|ensembl:ENST00000620225(transcript)|ensembl:ENST00000631566(transcript)|ensembl:ENST00000631610(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35227|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-5617472|reactome:R-HSA-8953750|uniprotkb:P35227(identity)|entrezgene/locuslink:7703(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:0dDjrgvWcP5Sx8h+qUj7awuM3ko9606 rogid:zppw56VrEl6gEFwtJMCN5cQkPxI9606 intact-crc:13327435383EA37B|rigid:WxmLmu1uyDG3D8+45FVqjzmR97s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P78364 uniprotkb:Q14781 intact:EBI-725403|uniprotkb:Q8WVM3|uniprotkb:Q9BU63|uniprotkb:D3DUV4|ensembl:ENSP00000437659|ensembl:ENSP00000440674 intact:EBI-745934|uniprotkb:Q9BTB1|uniprotkb:Q0VDA5|ensembl:ENSP00000308750 psi-mi:phc1_human(display_long)|uniprotkb:Early development regulatory protein 1(gene name synonym)|uniprotkb:PHC1(gene name)|psi-mi:PHC1(display_short)|uniprotkb:EDR1(gene name synonym)|uniprotkb:PH1(gene name synonym) psi-mi:cbx2_human(display_long)|uniprotkb:CBX2(gene name)|psi-mi:CBX2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834509|imex:IM-21659-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004417.2|ensembl:ENSG00000111752(gene)|ensembl:ENST00000543824(transcript)|ensembl:ENST00000544916(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:P78364|rcsb pdb:2L8E|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|dip:DIP-44567N|uniprotkb:P78364(identity)|entrezgene/locuslink:1911(identity)|ddbj/embl/genbank:BC017748(identity) refseq:NP_005180.1|refseq:NP_116036.1|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|go:"GO:0045137"(development of primary sexual characteristics)|interpro:IPR042796|mint:Q14781|rcsb pdb:2D9U|rcsb pdb:3H91|rcsb pdb:5EPK|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSG00000173894(gene)|ensembl:ENST00000310942(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|dip:DIP-48604N|uniprotkb:Q14781(identity)|entrezgene/locuslink:84733(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:0dDjrgvWcP5Sx8h+qUj7awuM3ko9606 rogid:220eC8UGlmAHHP2WAhZdAveHC3s9606 intact-crc:13327435383EA37B|rigid:WxmLmu1uyDG3D8+45FVqjzmR97s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P78364 uniprotkb:Q9HC52 intact:EBI-725403|uniprotkb:Q8WVM3|uniprotkb:Q9BU63|uniprotkb:D3DUV4|ensembl:ENSP00000437659|ensembl:ENSP00000440674 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 psi-mi:phc1_human(display_long)|uniprotkb:Early development regulatory protein 1(gene name synonym)|uniprotkb:PHC1(gene name)|psi-mi:PHC1(display_short)|uniprotkb:EDR1(gene name synonym)|uniprotkb:PH1(gene name synonym) psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834509|imex:IM-21659-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004417.2|ensembl:ENSG00000111752(gene)|ensembl:ENST00000543824(transcript)|ensembl:ENST00000544916(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:P78364|rcsb pdb:2L8E|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|dip:DIP-44567N|uniprotkb:P78364(identity)|entrezgene/locuslink:1911(identity)|ddbj/embl/genbank:BC017748(identity) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N|uniprotkb:Q9HC52(identity)|entrezgene/locuslink:57332(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:0dDjrgvWcP5Sx8h+qUj7awuM3ko9606 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 intact-crc:13327435383EA37B|rigid:WxmLmu1uyDG3D8+45FVqjzmR97s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXK0 uniprotkb:O95503 intact:EBI-713786|uniprotkb:Q8N306|uniprotkb:Q8TAG8|uniprotkb:A1L4Q1|uniprotkb:Q2TAL3|uniprotkb:Q5T0C1|uniprotkb:Q6NUJ6|uniprotkb:Q6ZQR1|uniprotkb:Q96BL4|uniprotkb:Q9Y4Y7|ensembl:ENSP00000257118|uniprotkb:D3DPR2|uniprotkb:A8KA40 intact:EBI-3951758|uniprotkb:A8KAH0|uniprotkb:Q96EM5|intact:EBI-28986885|ensembl:ENSP00000384490 psi-mi:phc2_human(display_long)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:PHC2(gene name)|psi-mi:PHC2(display_short)|uniprotkb:EDR2(gene name synonym)|uniprotkb:PH2(gene name synonym) psi-mi:cbx6_human(display_long)|uniprotkb:CBX6(gene name)|psi-mi:CBX6(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834564|imex:IM-21659-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR038603|mint:Q8IXK0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR013761(Sterile alpha motif-type)|ensembl:ENSG00000134686(gene)|ensembl:ENST00000257118(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|refseq:NP_004418.2|refseq:NP_932157.1|refseq:XP_016856005.1|refseq:XP_016856006.1|refseq:XP_016856007.1|refseq:XP_005270627.1|dip:DIP-34464N|uniprotkb:Q8IXK0(identity)|ddbj/embl/genbank:BC130630(identity)|entrezgene/locuslink:1912(identity) refseq:NP_001290423.1|ensembl:ENSG00000183741(gene)|refseq:NP_055107.3|ensembl:ENST00000407418(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:O95503|rcsb pdb:3GV6|rcsb pdb:3I90|reactome:R-HSA-2559580|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSP00000384490|dip:DIP-48605N|uniprotkb:O95503(identity)|entrezgene/locuslink:23466(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:7si/KU2tHoxviuCr70ncQERDWmY9606 rogid:4iNHCYe1bjb/JcurXP1iGoO/2uA9606 intact-crc:FFF569B190635026|rigid:2Fk+rqaamOgq1g7cdSEp4hOs7LU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXK0 uniprotkb:Q14781 intact:EBI-713786|uniprotkb:Q8N306|uniprotkb:Q8TAG8|uniprotkb:A1L4Q1|uniprotkb:Q2TAL3|uniprotkb:Q5T0C1|uniprotkb:Q6NUJ6|uniprotkb:Q6ZQR1|uniprotkb:Q96BL4|uniprotkb:Q9Y4Y7|ensembl:ENSP00000257118|uniprotkb:D3DPR2|uniprotkb:A8KA40 intact:EBI-745934|uniprotkb:Q9BTB1|uniprotkb:Q0VDA5|ensembl:ENSP00000308750 psi-mi:phc2_human(display_long)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:PHC2(gene name)|psi-mi:PHC2(display_short)|uniprotkb:EDR2(gene name synonym)|uniprotkb:PH2(gene name synonym) psi-mi:cbx2_human(display_long)|uniprotkb:CBX2(gene name)|psi-mi:CBX2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834564|imex:IM-21659-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR038603|mint:Q8IXK0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR013761(Sterile alpha motif-type)|ensembl:ENSG00000134686(gene)|ensembl:ENST00000257118(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|refseq:NP_004418.2|refseq:NP_932157.1|refseq:XP_016856005.1|refseq:XP_016856006.1|refseq:XP_016856007.1|refseq:XP_005270627.1|dip:DIP-34464N|uniprotkb:Q8IXK0(identity)|ddbj/embl/genbank:BC130630(identity)|entrezgene/locuslink:1912(identity) refseq:NP_005180.1|refseq:NP_116036.1|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|go:"GO:0045137"(development of primary sexual characteristics)|interpro:IPR042796|mint:Q14781|rcsb pdb:2D9U|rcsb pdb:3H91|rcsb pdb:5EPK|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSG00000173894(gene)|ensembl:ENST00000310942(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|dip:DIP-48604N|uniprotkb:Q14781(identity)|entrezgene/locuslink:84733(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:7si/KU2tHoxviuCr70ncQERDWmY9606 rogid:220eC8UGlmAHHP2WAhZdAveHC3s9606 intact-crc:FFF569B190635026|rigid:2Fk+rqaamOgq1g7cdSEp4hOs7LU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXK0 uniprotkb:O00257 intact:EBI-713786|uniprotkb:Q8N306|uniprotkb:Q8TAG8|uniprotkb:A1L4Q1|uniprotkb:Q2TAL3|uniprotkb:Q5T0C1|uniprotkb:Q6NUJ6|uniprotkb:Q6ZQR1|uniprotkb:Q96BL4|uniprotkb:Q9Y4Y7|ensembl:ENSP00000257118|uniprotkb:D3DPR2|uniprotkb:A8KA40 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 psi-mi:phc2_human(display_long)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:PHC2(gene name)|psi-mi:PHC2(display_short)|uniprotkb:EDR2(gene name synonym)|uniprotkb:PH2(gene name synonym) psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834564|imex:IM-21659-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR038603|mint:Q8IXK0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR013761(Sterile alpha motif-type)|ensembl:ENSG00000134686(gene)|ensembl:ENST00000257118(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|refseq:NP_004418.2|refseq:NP_932157.1|refseq:XP_016856005.1|refseq:XP_016856006.1|refseq:XP_016856007.1|refseq:XP_005270627.1|dip:DIP-34464N|uniprotkb:Q8IXK0(identity)|ddbj/embl/genbank:BC130630(identity)|entrezgene/locuslink:1912(identity) refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|entrezgene/locuslink:8535(identity)|uniprotkb:O00257(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:7si/KU2tHoxviuCr70ncQERDWmY9606 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 intact-crc:FFF569B190635026|rigid:2Fk+rqaamOgq1g7cdSEp4hOs7LU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXK0 uniprotkb:Q9H3G5 intact:EBI-713786|uniprotkb:Q8N306|uniprotkb:Q8TAG8|uniprotkb:A1L4Q1|uniprotkb:Q2TAL3|uniprotkb:Q5T0C1|uniprotkb:Q6NUJ6|uniprotkb:Q6ZQR1|uniprotkb:Q96BL4|uniprotkb:Q9Y4Y7|ensembl:ENSP00000257118|uniprotkb:D3DPR2|uniprotkb:A8KA40 intact:EBI-357542|uniprotkb:Q6UX20|uniprotkb:Q8NBL7|uniprotkb:Q96AR7|uniprotkb:Q9HB41|ensembl:ENSP00000265394|ensembl:ENSP00000379572|ensembl:ENSP00000387164|intact:EBI-1058665|uniprotkb:A4D1A4 psi-mi:phc2_human(display_long)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:PHC2(gene name)|psi-mi:PHC2(display_short)|uniprotkb:EDR2(gene name synonym)|uniprotkb:PH2(gene name synonym) psi-mi:cpvl_human(display_long)|uniprotkb:CPVL(gene name)|psi-mi:CPVL(display_short)|uniprotkb:VLP(gene name synonym)|uniprotkb:UNQ197/PRO223(orf name)|uniprotkb:PSEC0124(orf name)|uniprotkb:Carboxypeptidase, vitellogenic-like(gene name synonym)|uniprotkb:Vitellogenic carboxypeptidase-like protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834564|imex:IM-21659-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR038603|mint:Q8IXK0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR013761(Sterile alpha motif-type)|ensembl:ENSG00000134686(gene)|ensembl:ENST00000257118(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|refseq:NP_004418.2|refseq:NP_932157.1|refseq:XP_016856005.1|refseq:XP_016856006.1|refseq:XP_016856007.1|refseq:XP_005270627.1|dip:DIP-34464N|uniprotkb:Q8IXK0(identity)|ddbj/embl/genbank:BC130630(identity)|entrezgene/locuslink:1912(identity) ensembl:ENSG00000106066(gene)|ensembl:ENST00000265394(transcript)|ensembl:ENST00000396276(transcript)|ensembl:ENST00000409850(transcript)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR029058|mint:Q9H3G5|refseq:NP_061902.2|refseq:NP_112601.3|refseq:XP_011513739.1|refseq:NP_001334981.1|refseq:NP_001334983.1|uniprotkb:Q9H3G5(identity)|entrezgene/locuslink:54504(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:7si/KU2tHoxviuCr70ncQERDWmY9606 rogid:antgab61u6D+KmbopQeowXqSqWQ9606 intact-crc:FFF569B190635026|rigid:2Fk+rqaamOgq1g7cdSEp4hOs7LU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXK0 uniprotkb:O95931 intact:EBI-713786|uniprotkb:Q8N306|uniprotkb:Q8TAG8|uniprotkb:A1L4Q1|uniprotkb:Q2TAL3|uniprotkb:Q5T0C1|uniprotkb:Q6NUJ6|uniprotkb:Q6ZQR1|uniprotkb:Q96BL4|uniprotkb:Q9Y4Y7|ensembl:ENSP00000257118|uniprotkb:D3DPR2|uniprotkb:A8KA40 intact:EBI-3923843|uniprotkb:Q86T17|ensembl:ENSP00000216133 psi-mi:phc2_human(display_long)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:PHC2(gene name)|psi-mi:PHC2(display_short)|uniprotkb:EDR2(gene name synonym)|uniprotkb:PH2(gene name synonym) psi-mi:cbx7_human(display_long)|uniprotkb:CBX7(gene name)|psi-mi:CBX7(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834564|imex:IM-21659-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR038603|mint:Q8IXK0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR013761(Sterile alpha motif-type)|ensembl:ENSG00000134686(gene)|ensembl:ENST00000257118(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|refseq:NP_004418.2|refseq:NP_932157.1|refseq:XP_016856005.1|refseq:XP_016856006.1|refseq:XP_016856007.1|refseq:XP_005270627.1|dip:DIP-34464N|uniprotkb:Q8IXK0(identity)|ddbj/embl/genbank:BC130630(identity)|entrezgene/locuslink:1912(identity) refseq:NP_783640.1|ensembl:ENSG00000100307(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|mint:O95931|rcsb pdb:2K1B|rcsb pdb:2L12|rcsb pdb:2L1B|rcsb pdb:3GS2|rcsb pdb:4MN3|rcsb pdb:5EPJ|rcsb pdb:6V2R|ensembl:ENST00000216133(transcript)|dip:DIP-44565N|uniprotkb:O95931(identity)|entrezgene/locuslink:23492(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:7si/KU2tHoxviuCr70ncQERDWmY9606 rogid:LDXV9srMj1BL2CaSSot1Bn0/EW49606 intact-crc:FFF569B190635026|rigid:2Fk+rqaamOgq1g7cdSEp4hOs7LU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXK0 uniprotkb:Q9HC52 intact:EBI-713786|uniprotkb:Q8N306|uniprotkb:Q8TAG8|uniprotkb:A1L4Q1|uniprotkb:Q2TAL3|uniprotkb:Q5T0C1|uniprotkb:Q6NUJ6|uniprotkb:Q6ZQR1|uniprotkb:Q96BL4|uniprotkb:Q9Y4Y7|ensembl:ENSP00000257118|uniprotkb:D3DPR2|uniprotkb:A8KA40 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 psi-mi:phc2_human(display_long)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:PHC2(gene name)|psi-mi:PHC2(display_short)|uniprotkb:EDR2(gene name synonym)|uniprotkb:PH2(gene name synonym) psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834564|imex:IM-21659-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR038603|mint:Q8IXK0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR013761(Sterile alpha motif-type)|ensembl:ENSG00000134686(gene)|ensembl:ENST00000257118(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|refseq:NP_004418.2|refseq:NP_932157.1|refseq:XP_016856005.1|refseq:XP_016856006.1|refseq:XP_016856007.1|refseq:XP_005270627.1|dip:DIP-34464N|uniprotkb:Q8IXK0(identity)|ddbj/embl/genbank:BC130630(identity)|entrezgene/locuslink:1912(identity) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N|uniprotkb:Q9HC52(identity)|entrezgene/locuslink:57332(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:7si/KU2tHoxviuCr70ncQERDWmY9606 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 intact-crc:FFF569B190635026|rigid:2Fk+rqaamOgq1g7cdSEp4hOs7LU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXK0 uniprotkb:Q9UN30 intact:EBI-713786|uniprotkb:Q8N306|uniprotkb:Q8TAG8|uniprotkb:A1L4Q1|uniprotkb:Q2TAL3|uniprotkb:Q5T0C1|uniprotkb:Q6NUJ6|uniprotkb:Q6ZQR1|uniprotkb:Q96BL4|uniprotkb:Q9Y4Y7|ensembl:ENSP00000257118|uniprotkb:D3DPR2|uniprotkb:A8KA40 intact:EBI-6911404|ensembl:ENSP00000369380|uniprotkb:B2RA08|uniprotkb:Q5H969|uniprotkb:B0FZN6|uniprotkb:Q5H968 psi-mi:phc2_human(display_long)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:PHC2(gene name)|psi-mi:PHC2(display_short)|uniprotkb:EDR2(gene name synonym)|uniprotkb:PH2(gene name synonym) psi-mi:scml1_human(display_long)|uniprotkb:SCML1(gene name)|psi-mi:SCML1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834564|imex:IM-21659-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR038603|mint:Q8IXK0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR013761(Sterile alpha motif-type)|ensembl:ENSG00000134686(gene)|ensembl:ENST00000257118(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|refseq:NP_004418.2|refseq:NP_932157.1|refseq:XP_016856005.1|refseq:XP_016856006.1|refseq:XP_016856007.1|refseq:XP_005270627.1|dip:DIP-34464N|uniprotkb:Q8IXK0(identity)|ddbj/embl/genbank:BC130630(identity)|entrezgene/locuslink:1912(identity) ensembl:ENSG00000047634(gene)|ensembl:ENST00000380041(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q9UN30|refseq:XP_016885212.1|refseq:XP_006724571.1|refseq:NP_001032624.1|refseq:NP_001032625.1|refseq:NP_001032629.1|refseq:NP_006737.2|uniprotkb:Q9UN30(identity)|entrezgene/locuslink:6322(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:7si/KU2tHoxviuCr70ncQERDWmY9606 rogid:/eJ/2Xuw4P5GzHy1wGRxnYZ4hvY9606 intact-crc:FFF569B190635026|rigid:2Fk+rqaamOgq1g7cdSEp4hOs7LU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXK0 uniprotkb:P35226 intact:EBI-713786|uniprotkb:Q8N306|uniprotkb:Q8TAG8|uniprotkb:A1L4Q1|uniprotkb:Q2TAL3|uniprotkb:Q5T0C1|uniprotkb:Q6NUJ6|uniprotkb:Q6ZQR1|uniprotkb:Q96BL4|uniprotkb:Q9Y4Y7|ensembl:ENSP00000257118|uniprotkb:D3DPR2|uniprotkb:A8KA40 intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851 psi-mi:phc2_human(display_long)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:PHC2(gene name)|psi-mi:PHC2(display_short)|uniprotkb:EDR2(gene name synonym)|uniprotkb:PH2(gene name synonym) psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834564|imex:IM-21659-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR038603|mint:Q8IXK0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR013761(Sterile alpha motif-type)|ensembl:ENSG00000134686(gene)|ensembl:ENST00000257118(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|refseq:NP_004418.2|refseq:NP_932157.1|refseq:XP_016856005.1|refseq:XP_016856006.1|refseq:XP_016856007.1|refseq:XP_005270627.1|dip:DIP-34464N|uniprotkb:Q8IXK0(identity)|ddbj/embl/genbank:BC130630(identity)|entrezgene/locuslink:1912(identity) refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:P35226(identity)|entrezgene/locuslink:100532731(identity)|entrezgene/locuslink:648(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:7si/KU2tHoxviuCr70ncQERDWmY9606 rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606 intact-crc:FFF569B190635026|rigid:2Fk+rqaamOgq1g7cdSEp4hOs7LU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXK0 uniprotkb:Q9BQE3 intact:EBI-713786|uniprotkb:Q8N306|uniprotkb:Q8TAG8|uniprotkb:A1L4Q1|uniprotkb:Q2TAL3|uniprotkb:Q5T0C1|uniprotkb:Q6NUJ6|uniprotkb:Q6ZQR1|uniprotkb:Q96BL4|uniprotkb:Q9Y4Y7|ensembl:ENSP00000257118|uniprotkb:D3DPR2|uniprotkb:A8KA40 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:phc2_human(display_long)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:PHC2(gene name)|psi-mi:PHC2(display_short)|uniprotkb:EDR2(gene name synonym)|uniprotkb:PH2(gene name synonym) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834564|imex:IM-21659-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR038603|mint:Q8IXK0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR013761(Sterile alpha motif-type)|ensembl:ENSG00000134686(gene)|ensembl:ENST00000257118(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|refseq:NP_004418.2|refseq:NP_932157.1|refseq:XP_016856005.1|refseq:XP_016856006.1|refseq:XP_016856007.1|refseq:XP_005270627.1|dip:DIP-34464N|uniprotkb:Q8IXK0(identity)|ddbj/embl/genbank:BC130630(identity)|entrezgene/locuslink:1912(identity) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1|uniprotkb:Q9BQE3(identity)|entrezgene/locuslink:84790(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:7si/KU2tHoxviuCr70ncQERDWmY9606 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:FFF569B190635026|rigid:2Fk+rqaamOgq1g7cdSEp4hOs7LU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXK0 uniprotkb:P35227 intact:EBI-713786|uniprotkb:Q8N306|uniprotkb:Q8TAG8|uniprotkb:A1L4Q1|uniprotkb:Q2TAL3|uniprotkb:Q5T0C1|uniprotkb:Q6NUJ6|uniprotkb:Q6ZQR1|uniprotkb:Q96BL4|uniprotkb:Q9Y4Y7|ensembl:ENSP00000257118|uniprotkb:D3DPR2|uniprotkb:A8KA40 intact:EBI-2129767|uniprotkb:A6NGD8|ensembl:ENSP00000478517|ensembl:ENSP00000478970|ensembl:ENSP00000482063|ensembl:ENSP00000482815|ensembl:ENSP00000488868|ensembl:ENSP00000488872 psi-mi:phc2_human(display_long)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:PHC2(gene name)|psi-mi:PHC2(display_short)|uniprotkb:EDR2(gene name synonym)|uniprotkb:PH2(gene name synonym) psi-mi:pcgf2_human(display_long)|uniprotkb:PCGF2(gene name)|psi-mi:PCGF2(display_short)|uniprotkb:MEL18(gene name synonym)|uniprotkb:RNF110(gene name synonym)|uniprotkb:ZNF144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834564|imex:IM-21659-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR038603|mint:Q8IXK0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR013761(Sterile alpha motif-type)|ensembl:ENSG00000134686(gene)|ensembl:ENST00000257118(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|refseq:NP_004418.2|refseq:NP_932157.1|refseq:XP_016856005.1|refseq:XP_016856006.1|refseq:XP_016856007.1|refseq:XP_005270627.1|dip:DIP-34464N|uniprotkb:Q8IXK0(identity)|ddbj/embl/genbank:BC130630(identity)|entrezgene/locuslink:1912(identity) refseq:NP_009075.1|refseq:XP_016880505.1|refseq:XP_005257697.1|refseq:XP_005257698.1|refseq:XP_005257699.1|dip:DIP-41880N|ensembl:ENSG00000277258(gene)|ensembl:ENSG00000278644(gene)|ensembl:ENST00000610440(transcript)|ensembl:ENST00000611883(transcript)|ensembl:ENST00000616199(transcript)|ensembl:ENST00000620225(transcript)|ensembl:ENST00000631566(transcript)|ensembl:ENST00000631610(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35227|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-5617472|reactome:R-HSA-8953750|uniprotkb:P35227(identity)|entrezgene/locuslink:7703(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:7si/KU2tHoxviuCr70ncQERDWmY9606 rogid:zppw56VrEl6gEFwtJMCN5cQkPxI9606 intact-crc:FFF569B190635026|rigid:2Fk+rqaamOgq1g7cdSEp4hOs7LU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXK0 uniprotkb:Q99496 intact:EBI-713786|uniprotkb:Q8N306|uniprotkb:Q8TAG8|uniprotkb:A1L4Q1|uniprotkb:Q2TAL3|uniprotkb:Q5T0C1|uniprotkb:Q6NUJ6|uniprotkb:Q6ZQR1|uniprotkb:Q96BL4|uniprotkb:Q9Y4Y7|ensembl:ENSP00000257118|uniprotkb:D3DPR2|uniprotkb:A8KA40 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:phc2_human(display_long)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:PHC2(gene name)|psi-mi:PHC2(display_short)|uniprotkb:EDR2(gene name synonym)|uniprotkb:PH2(gene name synonym) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834564|imex:IM-21659-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR038603|mint:Q8IXK0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR013761(Sterile alpha motif-type)|ensembl:ENSG00000134686(gene)|ensembl:ENST00000257118(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|refseq:NP_004418.2|refseq:NP_932157.1|refseq:XP_016856005.1|refseq:XP_016856006.1|refseq:XP_016856007.1|refseq:XP_005270627.1|dip:DIP-34464N|uniprotkb:Q8IXK0(identity)|ddbj/embl/genbank:BC130630(identity)|entrezgene/locuslink:1912(identity) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|entrezgene/locuslink:6045(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:7si/KU2tHoxviuCr70ncQERDWmY9606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 intact-crc:FFF569B190635026|rigid:2Fk+rqaamOgq1g7cdSEp4hOs7LU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXK0 uniprotkb:Q06587 intact:EBI-713786|uniprotkb:Q8N306|uniprotkb:Q8TAG8|uniprotkb:A1L4Q1|uniprotkb:Q2TAL3|uniprotkb:Q5T0C1|uniprotkb:Q6NUJ6|uniprotkb:Q6ZQR1|uniprotkb:Q96BL4|uniprotkb:Q9Y4Y7|ensembl:ENSP00000257118|uniprotkb:D3DPR2|uniprotkb:A8KA40 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 psi-mi:phc2_human(display_long)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:PHC2(gene name)|psi-mi:PHC2(display_short)|uniprotkb:EDR2(gene name synonym)|uniprotkb:PH2(gene name synonym) psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834564|imex:IM-21659-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR038603|mint:Q8IXK0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR013761(Sterile alpha motif-type)|ensembl:ENSG00000134686(gene)|ensembl:ENST00000257118(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|refseq:NP_004418.2|refseq:NP_932157.1|refseq:XP_016856005.1|refseq:XP_016856006.1|refseq:XP_016856007.1|refseq:XP_005270627.1|dip:DIP-34464N|uniprotkb:Q8IXK0(identity)|ddbj/embl/genbank:BC130630(identity)|entrezgene/locuslink:1912(identity) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:7si/KU2tHoxviuCr70ncQERDWmY9606 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 intact-crc:FFF569B190635026|rigid:2Fk+rqaamOgq1g7cdSEp4hOs7LU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43189 uniprotkb:O75530 intact:EBI-530034|uniprotkb:B1AZX2|uniprotkb:B1AZX3|uniprotkb:O60929|uniprotkb:Q96KM7|uniprotkb:Q5SU07|uniprotkb:Q5SU08|ensembl:ENSP00000363640|ensembl:ENSP00000391901|ensembl:ENSP00000407295 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 psi-mi:phf1_human(display_long)|uniprotkb:PCL1(gene name synonym)|uniprotkb:Polycomb-like protein 1(gene name synonym)|uniprotkb:PHF1(gene name)|psi-mi:PHF1(display_short) psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834702|imex:IM-21659-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011512964.1|refseq:NP_002627.1|refseq:NP_077084.1|ensembl:ENSG00000112511(gene)|ensembl:ENSG00000225553(gene)|ensembl:ENST00000374516(transcript)|ensembl:ENST00000427869(transcript)|ensembl:ENST00000454914(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR031202|interpro:IPR040477|mint:O43189|rcsb pdb:2E5P|rcsb pdb:2M0O|rcsb pdb:4HCZ|rcsb pdb:5XFN|rcsb pdb:5XFO|rcsb pdb:5XFP|rcsb pdb:6WAT|rcsb pdb:6WAV|reactome:R-HSA-212300|dip:DIP-34001N|uniprotkb:O43189(identity)|ddbj/embl/genbank:BC008834(identity)|entrezgene/locuslink:5252(identity) refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:O75530(identity)|entrezgene/locuslink:8726(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:8n8g2LqzuOQb8cFC7tE1j/xBvkI9606 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 intact-crc:87B9999B187840DC|rigid:hzWodkER+DKr+w+pncLW6cfuucE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43189 uniprotkb:Q15910 intact:EBI-530034|uniprotkb:B1AZX2|uniprotkb:B1AZX3|uniprotkb:O60929|uniprotkb:Q96KM7|uniprotkb:Q5SU07|uniprotkb:Q5SU08|ensembl:ENSP00000363640|ensembl:ENSP00000391901|ensembl:ENSP00000407295 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 psi-mi:phf1_human(display_long)|uniprotkb:PCL1(gene name synonym)|uniprotkb:Polycomb-like protein 1(gene name synonym)|uniprotkb:PHF1(gene name)|psi-mi:PHF1(display_short) psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834702|imex:IM-21659-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011512964.1|refseq:NP_002627.1|refseq:NP_077084.1|ensembl:ENSG00000112511(gene)|ensembl:ENSG00000225553(gene)|ensembl:ENST00000374516(transcript)|ensembl:ENST00000427869(transcript)|ensembl:ENST00000454914(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR031202|interpro:IPR040477|mint:O43189|rcsb pdb:2E5P|rcsb pdb:2M0O|rcsb pdb:4HCZ|rcsb pdb:5XFN|rcsb pdb:5XFO|rcsb pdb:5XFP|rcsb pdb:6WAT|rcsb pdb:6WAV|reactome:R-HSA-212300|dip:DIP-34001N|uniprotkb:O43189(identity)|ddbj/embl/genbank:BC008834(identity)|entrezgene/locuslink:5252(identity) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N|uniprotkb:Q15910(identity)|entrezgene/locuslink:2146(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:8n8g2LqzuOQb8cFC7tE1j/xBvkI9606 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 intact-crc:87B9999B187840DC|rigid:hzWodkER+DKr+w+pncLW6cfuucE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43189 uniprotkb:Q15022 intact:EBI-530034|uniprotkb:B1AZX2|uniprotkb:B1AZX3|uniprotkb:O60929|uniprotkb:Q96KM7|uniprotkb:Q5SU07|uniprotkb:Q5SU08|ensembl:ENSP00000363640|ensembl:ENSP00000391901|ensembl:ENSP00000407295 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 psi-mi:phf1_human(display_long)|uniprotkb:PCL1(gene name synonym)|uniprotkb:Polycomb-like protein 1(gene name synonym)|uniprotkb:PHF1(gene name)|psi-mi:PHF1(display_short) psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834702|imex:IM-21659-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011512964.1|refseq:NP_002627.1|refseq:NP_077084.1|ensembl:ENSG00000112511(gene)|ensembl:ENSG00000225553(gene)|ensembl:ENST00000374516(transcript)|ensembl:ENST00000427869(transcript)|ensembl:ENST00000454914(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR031202|interpro:IPR040477|mint:O43189|rcsb pdb:2E5P|rcsb pdb:2M0O|rcsb pdb:4HCZ|rcsb pdb:5XFN|rcsb pdb:5XFO|rcsb pdb:5XFP|rcsb pdb:6WAT|rcsb pdb:6WAV|reactome:R-HSA-212300|dip:DIP-34001N|uniprotkb:O43189(identity)|ddbj/embl/genbank:BC008834(identity)|entrezgene/locuslink:5252(identity) dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:Q15022(identity)|entrezgene/locuslink:23512(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:8n8g2LqzuOQb8cFC7tE1j/xBvkI9606 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 intact-crc:87B9999B187840DC|rigid:hzWodkER+DKr+w+pncLW6cfuucE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43189 uniprotkb:Q09028 intact:EBI-530034|uniprotkb:B1AZX2|uniprotkb:B1AZX3|uniprotkb:O60929|uniprotkb:Q96KM7|uniprotkb:Q5SU07|uniprotkb:Q5SU08|ensembl:ENSP00000363640|ensembl:ENSP00000391901|ensembl:ENSP00000407295 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 psi-mi:phf1_human(display_long)|uniprotkb:PCL1(gene name synonym)|uniprotkb:Polycomb-like protein 1(gene name synonym)|uniprotkb:PHF1(gene name)|psi-mi:PHF1(display_short) psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834702|imex:IM-21659-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011512964.1|refseq:NP_002627.1|refseq:NP_077084.1|ensembl:ENSG00000112511(gene)|ensembl:ENSG00000225553(gene)|ensembl:ENST00000374516(transcript)|ensembl:ENST00000427869(transcript)|ensembl:ENST00000454914(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR031202|interpro:IPR040477|mint:O43189|rcsb pdb:2E5P|rcsb pdb:2M0O|rcsb pdb:4HCZ|rcsb pdb:5XFN|rcsb pdb:5XFO|rcsb pdb:5XFP|rcsb pdb:6WAT|rcsb pdb:6WAV|reactome:R-HSA-212300|dip:DIP-34001N|uniprotkb:O43189(identity)|ddbj/embl/genbank:BC008834(identity)|entrezgene/locuslink:5252(identity) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|entrezgene/locuslink:5928(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:8n8g2LqzuOQb8cFC7tE1j/xBvkI9606 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 intact-crc:87B9999B187840DC|rigid:hzWodkER+DKr+w+pncLW6cfuucE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43189 uniprotkb:P35659 intact:EBI-530034|uniprotkb:B1AZX2|uniprotkb:B1AZX3|uniprotkb:O60929|uniprotkb:Q96KM7|uniprotkb:Q5SU07|uniprotkb:Q5SU08|ensembl:ENSP00000363640|ensembl:ENSP00000391901|ensembl:ENSP00000407295 intact:EBI-301977|uniprotkb:Q5TGV4|uniprotkb:Q5TGV5|uniprotkb:B2R6K6|ensembl:ENSP00000498335|ensembl:ENSP00000498653|uniprotkb:B4DN37 psi-mi:phf1_human(display_long)|uniprotkb:PCL1(gene name synonym)|uniprotkb:Polycomb-like protein 1(gene name synonym)|uniprotkb:PHF1(gene name)|psi-mi:PHF1(display_short) psi-mi:dek_human(display_long)|uniprotkb:DEK(gene name)|psi-mi:DEK(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834702|imex:IM-21659-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011512964.1|refseq:NP_002627.1|refseq:NP_077084.1|ensembl:ENSG00000112511(gene)|ensembl:ENSG00000225553(gene)|ensembl:ENST00000374516(transcript)|ensembl:ENST00000427869(transcript)|ensembl:ENST00000454914(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR031202|interpro:IPR040477|mint:O43189|rcsb pdb:2E5P|rcsb pdb:2M0O|rcsb pdb:4HCZ|rcsb pdb:5XFN|rcsb pdb:5XFO|rcsb pdb:5XFP|rcsb pdb:6WAT|rcsb pdb:6WAV|reactome:R-HSA-212300|dip:DIP-34001N|uniprotkb:O43189(identity)|ddbj/embl/genbank:BC008834(identity)|entrezgene/locuslink:5252(identity) ensembl:ENSG00000124795(gene)|ensembl:ENST00000652576(transcript)|ensembl:ENST00000652689(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0019079"(viral genome replication)|go:"GO:0042393"(histone binding)|go:"GO:0043292"(contractile fiber)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR014876(DEK C terminal)|interpro:IPR044198|mint:P35659|rcsb pdb:1Q1V|rcsb pdb:2JX3|reactome:R-HSA-8864260|reactome:R-HSA-5250924|reactome:R-HSA-9616222|refseq:NP_001128181.1|refseq:NP_003463.1|uniprotkb:P35659(identity)|entrezgene/locuslink:7913(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:8n8g2LqzuOQb8cFC7tE1j/xBvkI9606 rogid:vHgpAwD3bj+BnjUPeNSIlouymfg9606 intact-crc:87B9999B187840DC|rigid:hzWodkER+DKr+w+pncLW6cfuucE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43189 uniprotkb:Q96JN0 intact:EBI-530034|uniprotkb:B1AZX2|uniprotkb:B1AZX3|uniprotkb:O60929|uniprotkb:Q96KM7|uniprotkb:Q5SU07|uniprotkb:Q5SU08|ensembl:ENSP00000363640|ensembl:ENSP00000391901|ensembl:ENSP00000407295 intact:EBI-746045|uniprotkb:Q9H945|uniprotkb:Q9Y457|ensembl:ENSP00000348298|ensembl:ENSP00000360138|ensembl:ENSP00000360144|ensembl:ENSP00000501560|ensembl:ENSP00000501639|ensembl:ENSP00000502633|intact:EBI-8833163|uniprotkb:D3DR47|uniprotkb:Q5VW16|uniprotkb:Q7Z723|uniprotkb:Q86T32|uniprotkb:Q86T33|uniprotkb:Q8N3L6|uniprotkb:Q8N655 psi-mi:phf1_human(display_long)|uniprotkb:PCL1(gene name synonym)|uniprotkb:Polycomb-like protein 1(gene name synonym)|uniprotkb:PHF1(gene name)|psi-mi:PHF1(display_short) psi-mi:lcor_human(display_long)|uniprotkb:LCOR(gene name)|psi-mi:LCOR(display_short)|uniprotkb:C10orf12(gene name synonym)|uniprotkb:KIAA1795(gene name synonym)|uniprotkb:MLR2(gene name synonym)|uniprotkb:Mblk1-related protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834702|imex:IM-21659-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011512964.1|refseq:NP_002627.1|refseq:NP_077084.1|ensembl:ENSG00000112511(gene)|ensembl:ENSG00000225553(gene)|ensembl:ENST00000374516(transcript)|ensembl:ENST00000427869(transcript)|ensembl:ENST00000454914(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR031202|interpro:IPR040477|mint:O43189|rcsb pdb:2E5P|rcsb pdb:2M0O|rcsb pdb:4HCZ|rcsb pdb:5XFN|rcsb pdb:5XFO|rcsb pdb:5XFP|rcsb pdb:6WAT|rcsb pdb:6WAV|reactome:R-HSA-212300|dip:DIP-34001N|uniprotkb:O43189(identity)|ddbj/embl/genbank:BC008834(identity)|entrezgene/locuslink:5252(identity) ensembl:ENSG00000196233(gene)|ensembl:ENST00000356016(transcript)|ensembl:ENST00000371097(transcript)|ensembl:ENST00000371103(transcript)|ensembl:ENST00000675471(transcript)|ensembl:ENST00000675537(transcript)|ensembl:ENST00000675971(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|mint:Q96JN0|rcsb pdb:2COB|refseq:NP_001164236.1|refseq:NP_001164237.1|refseq:NP_115816.2|refseq:XP_016872275.1|refseq:XP_016872276.1|refseq:XP_016872277.1|refseq:NP_001333445.1|uniprotkb:Q8N655(identity)|entrezgene/locuslink:26148(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:8n8g2LqzuOQb8cFC7tE1j/xBvkI9606 rogid:cOnk6EDDff86yaG1uG+dxEQ1Z689606 intact-crc:87B9999B187840DC|rigid:hzWodkER+DKr+w+pncLW6cfuucE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43189 uniprotkb:P22087 intact:EBI-530034|uniprotkb:B1AZX2|uniprotkb:B1AZX3|uniprotkb:O60929|uniprotkb:Q96KM7|uniprotkb:Q5SU07|uniprotkb:Q5SU08|ensembl:ENSP00000363640|ensembl:ENSP00000391901|ensembl:ENSP00000407295 intact:EBI-358318|uniprotkb:O75259|uniprotkb:Q6IAT5|uniprotkb:Q9UPI6|ensembl:ENSP00000221801|ensembl:ENSP00000487390|uniprotkb:B5BUE8 psi-mi:phf1_human(display_long)|uniprotkb:PCL1(gene name synonym)|uniprotkb:Polycomb-like protein 1(gene name synonym)|uniprotkb:PHF1(gene name)|psi-mi:PHF1(display_short) psi-mi:fbrl_human(display_long)|uniprotkb:FBL(gene name)|psi-mi:FBL(display_short)|uniprotkb:FIB1(gene name synonym)|uniprotkb:FLRN(gene name synonym)|uniprotkb:Histone-glutamine methyltransferase(gene name synonym)|uniprotkb:34 kDa nucleolar scleroderma antigen(gene name synonym)|uniprotkb:U6 snRNA 2'-O-methyltransferase fibrillarin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834702|imex:IM-21659-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011512964.1|refseq:NP_002627.1|refseq:NP_077084.1|ensembl:ENSG00000112511(gene)|ensembl:ENSG00000225553(gene)|ensembl:ENST00000374516(transcript)|ensembl:ENST00000427869(transcript)|ensembl:ENST00000454914(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR031202|interpro:IPR040477|mint:O43189|rcsb pdb:2E5P|rcsb pdb:2M0O|rcsb pdb:4HCZ|rcsb pdb:5XFN|rcsb pdb:5XFO|rcsb pdb:5XFP|rcsb pdb:6WAT|rcsb pdb:6WAV|reactome:R-HSA-212300|dip:DIP-34001N|uniprotkb:O43189(identity)|ddbj/embl/genbank:BC008834(identity)|entrezgene/locuslink:5252(identity) refseq:NP_001427.2|ensembl:ENSG00000105202(gene)|ensembl:ENSG00000280548(gene)|ensembl:ENST00000221801(transcript)|ensembl:ENST00000625241(transcript)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001650"(fibrillar center)|go:"GO:0001651"(dense fibrillar component)|go:"GO:0001652"(granular component)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0008649"(rRNA methyltransferase activity)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0031167"(rRNA methylation)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0048254"(snoRNA localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990258"(histone glutamine methylation)|go:"GO:1990259"(histone-glutamine methyltransferase activity)|interpro:IPR000692(Fibrillarin)|interpro:IPR020813|interpro:IPR029063|mint:P22087|rcsb pdb:2IPX|reactome:R-HSA-6790901|reactome:R-HSA-6791226|dip:DIP-27569N|uniprotkb:P22087(identity)|entrezgene/locuslink:2091(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:8n8g2LqzuOQb8cFC7tE1j/xBvkI9606 rogid:8m8FDRSxGNKNXpJMcWWbcHL3uss9606 intact-crc:87B9999B187840DC|rigid:hzWodkER+DKr+w+pncLW6cfuucE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43189 uniprotkb:Q92800 intact:EBI-530034|uniprotkb:B1AZX2|uniprotkb:B1AZX3|uniprotkb:O60929|uniprotkb:Q96KM7|uniprotkb:Q5SU07|uniprotkb:Q5SU08|ensembl:ENSP00000363640|ensembl:ENSP00000391901|ensembl:ENSP00000407295 intact:EBI-8830732|uniprotkb:B4E3R7|uniprotkb:O43287|uniprotkb:A6NCH6|uniprotkb:Q14459|uniprotkb:Q53XP3|uniprotkb:B4DSS2|uniprotkb:B4DIJ1|uniprotkb:B4DIZ7|ensembl:ENSP00000404658|ensembl:ENSP00000466924 psi-mi:phf1_human(display_long)|uniprotkb:PCL1(gene name synonym)|uniprotkb:Polycomb-like protein 1(gene name synonym)|uniprotkb:PHF1(gene name)|psi-mi:PHF1(display_short) psi-mi:ezh1_human(display_long)|uniprotkb:ENX-2(gene name synonym)|uniprotkb:Enhancer of zeste homolog 1(gene name synonym)|uniprotkb:KIAA0388(gene name synonym)|uniprotkb:EZH1(gene name)|psi-mi:EZH1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834702|imex:IM-21659-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011512964.1|refseq:NP_002627.1|refseq:NP_077084.1|ensembl:ENSG00000112511(gene)|ensembl:ENSG00000225553(gene)|ensembl:ENST00000374516(transcript)|ensembl:ENST00000427869(transcript)|ensembl:ENST00000454914(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR031202|interpro:IPR040477|mint:O43189|rcsb pdb:2E5P|rcsb pdb:2M0O|rcsb pdb:4HCZ|rcsb pdb:5XFN|rcsb pdb:5XFO|rcsb pdb:5XFP|rcsb pdb:6WAT|rcsb pdb:6WAV|reactome:R-HSA-212300|dip:DIP-34001N|uniprotkb:O43189(identity)|ddbj/embl/genbank:BC008834(identity)|entrezgene/locuslink:5252(identity) refseq:NP_001308008.1|refseq:NP_001308010.1|refseq:NP_001308011.1|refseq:NP_001982.2|dip:DIP-58580N|ensembl:ENSG00000108799(gene)|ensembl:ENST00000428826(transcript)|ensembl:ENST00000592743(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0021766"(hippocampus development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0031507"(heterochromatin assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR021654|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR032926|interpro:IPR041343|interpro:IPR041355|interpro:IPR044438|mint:Q92800|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|uniprotkb:Q92800(identity)|entrezgene/locuslink:2145(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:8n8g2LqzuOQb8cFC7tE1j/xBvkI9606 rogid:qp3eqBCgiaoA6VSSyqpW1d9YKN49606 intact-crc:87B9999B187840DC|rigid:hzWodkER+DKr+w+pncLW6cfuucE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43189 uniprotkb:P04637 intact:EBI-530034|uniprotkb:B1AZX2|uniprotkb:B1AZX3|uniprotkb:O60929|uniprotkb:Q96KM7|uniprotkb:Q5SU07|uniprotkb:Q5SU08|ensembl:ENSP00000363640|ensembl:ENSP00000391901|ensembl:ENSP00000407295 intact:EBI-366083|uniprotkb:Q15086|uniprotkb:Q15087|uniprotkb:Q15088|uniprotkb:Q16535|uniprotkb:Q16807|uniprotkb:Q16808|uniprotkb:Q16809|uniprotkb:Q16810|uniprotkb:Q16811|uniprotkb:Q16848|uniprotkb:Q86UG1|uniprotkb:Q8J016|uniprotkb:Q99659|uniprotkb:Q9BTM4|uniprotkb:Q9HAQ8|uniprotkb:Q9NP68|uniprotkb:Q9NPJ2|uniprotkb:Q9NZD0|uniprotkb:Q9UBI2|uniprotkb:Q9UQ61|ensembl:ENSP00000269305|ensembl:ENSP00000391478|intact:EBI-28980681|uniprotkb:Q2XN98|uniprotkb:Q3LRW1|uniprotkb:Q3LRW2|uniprotkb:Q3LRW3|uniprotkb:Q3LRW4|uniprotkb:Q3LRW5 psi-mi:phf1_human(display_long)|uniprotkb:PCL1(gene name synonym)|uniprotkb:Polycomb-like protein 1(gene name synonym)|uniprotkb:PHF1(gene name)|psi-mi:PHF1(display_short) psi-mi:p53_human(display_long)|uniprotkb:TP53(gene name)|psi-mi:TP53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym)|uniprotkb:Phosphoprotein p53(gene name synonym)|uniprotkb:Antigen NY-CO-13(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834702|imex:IM-21659-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011512964.1|refseq:NP_002627.1|refseq:NP_077084.1|ensembl:ENSG00000112511(gene)|ensembl:ENSG00000225553(gene)|ensembl:ENST00000374516(transcript)|ensembl:ENST00000427869(transcript)|ensembl:ENST00000454914(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR031202|interpro:IPR040477|mint:O43189|rcsb pdb:2E5P|rcsb pdb:2M0O|rcsb pdb:4HCZ|rcsb pdb:5XFN|rcsb pdb:5XFO|rcsb pdb:5XFP|rcsb pdb:6WAT|rcsb pdb:6WAV|reactome:R-HSA-212300|dip:DIP-34001N|uniprotkb:O43189(identity)|ddbj/embl/genbank:BC008834(identity)|entrezgene/locuslink:5252(identity) refseq:NP_001263624.1|refseq:NP_001263625.1|ensembl:ENSG00000141510(gene)|ensembl:ENST00000269305(transcript)|ensembl:ENST00000445888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0002020"(protease binding)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0031497"(chromatin assembly)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034103"(regulation of tissue remodeling)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035033"(histone deacetylase regulator activity)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035690"|go:"GO:0035794"(positive regulation of mitochondrial membrane permeability)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0006983"(ER overload response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007369"(gastrulation)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0043621"(protein self-association)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048512"(circadian behavior)|go:"GO:0048539"(bone marrow development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062100"(positive regulation of programmed necrotic cell death)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071494"(cellular response to UV-C)|go:"GO:0072331"(signal transduction by p53 class mediator)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:0090399"(replicative senescence)|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097252"(oligodendrocyte apoptotic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1902253"(regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904024"(negative regulation of glucose catabolic process to lactate via pyruvate)|go:"GO:1905856"(negative regulation of pentose-phosphate shunt)|go:"GO:1990144"(intrinsic apoptotic signaling pathway in response to hypoxia)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000269"(regulation of fibroblast apoptotic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009299"(mRNA transcription)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009651"(response to salt stress)|go:"GO:0010165"(response to X-ray)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016032"(viral process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013872("p53 transactivation domain (TAD)")|interpro:IPR036674|interpro:IPR040926|rcsb pdb:2ATA|rcsb pdb:2B3G|rcsb pdb:2BIM|rcsb pdb:2BIN|rcsb pdb:2BIO|rcsb pdb:2BIP|rcsb pdb:2AHI|rcsb pdb:2BIQ|rcsb pdb:2F1X|rcsb pdb:2FEJ|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2GS0|rcsb pdb:2H1L|rcsb pdb:2H2D|rcsb pdb:2H2F|rcsb pdb:2H4F|rcsb pdb:2H4H|rcsb pdb:2H4J|rcsb pdb:2H59|rcsb pdb:2J0Z|rcsb pdb:2J10|rcsb pdb:2J11|rcsb pdb:2J1W|rcsb pdb:2J1X|rcsb pdb:2J1Y|rcsb pdb:2J1Z|rcsb pdb:2J20|rcsb pdb:2J21|rcsb pdb:2K8F|rcsb pdb:2L14|rcsb pdb:2LY4|rcsb pdb:2MEJ|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:2MWY|rcsb pdb:2MZD|rcsb pdb:2OCJ|rcsb pdb:2PCX|rcsb pdb:1A1U|rcsb pdb:1AIE|rcsb pdb:1C26|rcsb pdb:1DT7|rcsb pdb:1GZH|rcsb pdb:1H26|rcsb pdb:1HS5|rcsb pdb:1JSP|rcsb pdb:1KZY|rcsb pdb:1MA3|rcsb pdb:1OLG|rcsb pdb:1OLH|rcsb pdb:1PES|rcsb pdb:1PET|mint:P04637|rcsb pdb:1SAE|rcsb pdb:1SAF|rcsb pdb:1SAK|rcsb pdb:1SAL|rcsb pdb:1TSR|rcsb pdb:1TUP|rcsb pdb:1UOL|rcsb pdb:1XQH|rcsb pdb:1YC5|rcsb pdb:1YCQ|rcsb pdb:1YCR|rcsb pdb:1YCS|rcsb pdb:2AC0|rcsb pdb:2ADY|refseq:NP_000537.3|refseq:NP_001119584.1|refseq:NP_001119585.1|refseq:NP_001119586.1|refseq:NP_001119587.1|refseq:NP_001119588.1|refseq:NP_001119589.1|rcsb pdb:2RUK|rcsb pdb:2VUK|rcsb pdb:3Q06|rcsb pdb:2WGX|rcsb pdb:2X0U|rcsb pdb:2X0V|rcsb pdb:2X0W|rcsb pdb:2XWR|rcsb pdb:2YBG|rcsb pdb:2YDR|rcsb pdb:2Z5S|rcsb pdb:2Z5T|rcsb pdb:3SAK|rcsb pdb:3D05|rcsb pdb:3D06|rcsb pdb:3D07|rcsb pdb:3D08|rcsb pdb:3D09|rcsb pdb:3D0A|rcsb pdb:3DAB|rcsb pdb:3DAC|rcsb pdb:3IGK|rcsb pdb:3IGL|rcsb pdb:3KMD|rcsb pdb:3TG5|rcsb pdb:3KZ8|rcsb pdb:3LW1|rcsb pdb:3OQ5|rcsb pdb:3PDH|rcsb pdb:3Q01|rcsb pdb:3Q05|rcsb pdb:3TS8|rcsb pdb:3ZME|rcsb pdb:4AGM|rcsb pdb:4AGN|rcsb pdb:4AGO|rcsb pdb:4AGP|rcsb pdb:4AGQ|rcsb pdb:4BUZ|rcsb pdb:4BV2|rcsb pdb:4HFZ|rcsb pdb:4HJE|rcsb pdb:4IBQ|rcsb pdb:4IBS|rcsb pdb:4IBT|rcsb pdb:4IBU|rcsb pdb:4IBV|rcsb pdb:4IBW|rcsb pdb:4IBY|rcsb pdb:4IBZ|rcsb pdb:4IJT|rcsb pdb:4KVP|rcsb pdb:4LO9|rcsb pdb:4LOE|rcsb pdb:4LOF|rcsb pdb:4MZI|rcsb pdb:4MZR|rcsb pdb:4QO1|rcsb pdb:4RP6|rcsb pdb:4RP7|rcsb pdb:4X34|rcsb pdb:4XR8|rcsb pdb:4ZZJ|rcsb pdb:5A7B|rcsb pdb:5AB9|rcsb pdb:5ABA|rcsb pdb:4AGL|rcsb pdb:5AOI|rcsb pdb:5AOJ|rcsb pdb:5AOK|rcsb pdb:5AOL|rcsb pdb:5AOM|rcsb pdb:6XRE|rcsb pdb:7BWN|rcsb pdb:7DHY|rcsb pdb:7DHZ|rcsb pdb:7EL4|reactome:R-HSA-111448|reactome:R-HSA-139915|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-2559586|reactome:R-HSA-3232118|reactome:R-HSA-349425|reactome:R-HSA-390471|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5693565|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804114|reactome:R-HSA-6804115|reactome:R-HSA-6804116|reactome:R-HSA-6804754|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-69473|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8853884|reactome:R-HSA-8941855|reactome:R-HSA-8943724|reactome:R-HSA-983231|rcsb pdb:5ECG|rcsb pdb:5G4M|rcsb pdb:5G4N|rcsb pdb:5BUA|rcsb pdb:5G4O|rcsb pdb:5HOU|rcsb pdb:5HP0|rcsb pdb:5HPD|rcsb pdb:5LAP|rcsb pdb:5LGY|rcsb pdb:5MCT|rcsb pdb:5MCU|rcsb pdb:5MCV|rcsb pdb:5MCW|rcsb pdb:5MF7|rcsb pdb:5MG7|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5O1A|rcsb pdb:5O1B|rcsb pdb:5O1C|rcsb pdb:5O1D|rcsb pdb:5O1E|rcsb pdb:5O1F|rcsb pdb:5O1G|rcsb pdb:5O1H|rcsb pdb:5O1I|rcsb pdb:5OL0|rcsb pdb:5UN8|rcsb pdb:5XZC|rcsb pdb:6FF9|rcsb pdb:6FJ5|rcsb pdb:6GGA|rcsb pdb:6GGB|rcsb pdb:6GGC|rcsb pdb:6GGD|rcsb pdb:6GGE|rcsb pdb:6GGF|rcsb pdb:6LHD|rcsb pdb:6R5L|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:6RWS|rcsb pdb:6RWU|rcsb pdb:6RX2|rcsb pdb:6RZ3|rcsb pdb:6S39|rcsb pdb:6S40|rcsb pdb:6S9Q|rcsb pdb:6SHZ|rcsb pdb:6SI0|rcsb pdb:6SI1|rcsb pdb:6SI2|rcsb pdb:6SI3|rcsb pdb:6SI4|rcsb pdb:6SIN|rcsb pdb:6SIO|rcsb pdb:6SIP|rcsb pdb:6SIQ|rcsb pdb:6SL6|rcsb pdb:6SLV|rcsb pdb:6T58|rcsb pdb:6V4F|rcsb pdb:6V4H|rcsb pdb:6VQO|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6S3C|ensembl:ENSP00000269305|ensembl:ENST00000420246|ensembl:ENSP00000391127|ensembl:ENSP00000391478|ensembl:ENST00000455263|ensembl:ENSP00000398846|ensembl:ENST00000504290|ensembl:ENSP00000484409|ensembl:ENST00000504937|ensembl:ENSP00000481179|ensembl:ENST00000510385|ensembl:ENSP00000478499|ensembl:ENST00000610292|ensembl:ENSP00000478219|ensembl:ENST00000610538|ensembl:ENSP00000480868|ensembl:ENST00000619485|ensembl:ENSP00000482537|ensembl:ENST00000620739|ensembl:ENSP00000481638|ensembl:ENST00000622645|ensembl:ENSP00000482222|refseq:NP_001119590.1|refseq:NP_001263626.1|refseq:NP_001263627.1|refseq:NP_001263628.1|refseq:NP_001263689.1|refseq:NP_001263690.1|dip:DIP-368N|uniprotkb:P04637(identity)|entrezgene/locuslink:7157(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:8n8g2LqzuOQb8cFC7tE1j/xBvkI9606 rogid:fGN3kSCGIpi/D6d/X5kaB0Xu8/k9606 intact-crc:87B9999B187840DC|rigid:hzWodkER+DKr+w+pncLW6cfuucE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43189 uniprotkb:P50990 intact:EBI-530034|uniprotkb:B1AZX2|uniprotkb:B1AZX3|uniprotkb:O60929|uniprotkb:Q96KM7|uniprotkb:Q5SU07|uniprotkb:Q5SU08|ensembl:ENSP00000363640|ensembl:ENSP00000391901|ensembl:ENSP00000407295 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:phf1_human(display_long)|uniprotkb:PCL1(gene name synonym)|uniprotkb:Polycomb-like protein 1(gene name synonym)|uniprotkb:PHF1(gene name)|psi-mi:PHF1(display_short) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834702|imex:IM-21659-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011512964.1|refseq:NP_002627.1|refseq:NP_077084.1|ensembl:ENSG00000112511(gene)|ensembl:ENSG00000225553(gene)|ensembl:ENST00000374516(transcript)|ensembl:ENST00000427869(transcript)|ensembl:ENST00000454914(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR031202|interpro:IPR040477|mint:O43189|rcsb pdb:2E5P|rcsb pdb:2M0O|rcsb pdb:4HCZ|rcsb pdb:5XFN|rcsb pdb:5XFO|rcsb pdb:5XFP|rcsb pdb:6WAT|rcsb pdb:6WAV|reactome:R-HSA-212300|dip:DIP-34001N|uniprotkb:O43189(identity)|ddbj/embl/genbank:BC008834(identity)|entrezgene/locuslink:5252(identity) refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N|uniprotkb:P50990(identity)|entrezgene/locuslink:10694(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:8n8g2LqzuOQb8cFC7tE1j/xBvkI9606 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 intact-crc:87B9999B187840DC|rigid:hzWodkER+DKr+w+pncLW6cfuucE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43189 uniprotkb:Q16576 intact:EBI-530034|uniprotkb:B1AZX2|uniprotkb:B1AZX3|uniprotkb:O60929|uniprotkb:Q96KM7|uniprotkb:Q5SU07|uniprotkb:Q5SU08|ensembl:ENSP00000363640|ensembl:ENSP00000391901|ensembl:ENSP00000407295 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 psi-mi:phf1_human(display_long)|uniprotkb:PCL1(gene name synonym)|uniprotkb:Polycomb-like protein 1(gene name synonym)|uniprotkb:PHF1(gene name)|psi-mi:PHF1(display_short) psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834702|imex:IM-21659-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011512964.1|refseq:NP_002627.1|refseq:NP_077084.1|ensembl:ENSG00000112511(gene)|ensembl:ENSG00000225553(gene)|ensembl:ENST00000374516(transcript)|ensembl:ENST00000427869(transcript)|ensembl:ENST00000454914(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR031202|interpro:IPR040477|mint:O43189|rcsb pdb:2E5P|rcsb pdb:2M0O|rcsb pdb:4HCZ|rcsb pdb:5XFN|rcsb pdb:5XFO|rcsb pdb:5XFP|rcsb pdb:6WAT|rcsb pdb:6WAV|reactome:R-HSA-212300|dip:DIP-34001N|uniprotkb:O43189(identity)|ddbj/embl/genbank:BC008834(identity)|entrezgene/locuslink:5252(identity) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|entrezgene/locuslink:5931(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:8n8g2LqzuOQb8cFC7tE1j/xBvkI9606 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 intact-crc:87B9999B187840DC|rigid:hzWodkER+DKr+w+pncLW6cfuucE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NDX5 uniprotkb:O95503 intact:EBI-1223801|uniprotkb:Q5HYF0|uniprotkb:Q6NSG2|uniprotkb:Q8NFT7|uniprotkb:Q8NFZ1|uniprotkb:Q8TBM2|uniprotkb:Q9H971|uniprotkb:Q9H9I4|uniprotkb:A2RRP9|ensembl:ENSP00000420271 intact:EBI-3951758|uniprotkb:A8KAH0|uniprotkb:Q96EM5|intact:EBI-28986885|ensembl:ENSP00000384490 psi-mi:phc3_human(display_long)|uniprotkb:PHC3(gene name)|psi-mi:PHC3(display_short)|uniprotkb:EDR3(gene name synonym)|uniprotkb:PH3(gene name synonym)|uniprotkb:Homolog of polyhomeotic 3(gene name synonym)|uniprotkb:Early development regulatory protein 3(gene name synonym) psi-mi:cbx6_human(display_long)|uniprotkb:CBX6(gene name)|psi-mi:CBX6(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834623|imex:IM-21659-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079223.3|refseq:NP_001295045.1|ensembl:ENSP00000420271|ensembl:ENST00000495893|ensembl:ENSP00000420294|ensembl:ENST00000497658|ensembl:ENSP00000420454|ensembl:ENSG00000173889(gene)|ensembl:ENST00000494943(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:Q8NDX5|rcsb pdb:4PZN|rcsb pdb:4PZO|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q8NDX5(identity)|entrezgene/locuslink:80012(identity)|ddbj/embl/genbank:BC131772(identity) refseq:NP_001290423.1|ensembl:ENSG00000183741(gene)|refseq:NP_055107.3|ensembl:ENST00000407418(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:O95503|rcsb pdb:3GV6|rcsb pdb:3I90|reactome:R-HSA-2559580|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSP00000384490|dip:DIP-48605N|uniprotkb:O95503(identity)|entrezgene/locuslink:23466(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2015/12/04 rogid:hB1EMs+lCv19uuJ1O7+QiVCUoo89606 rogid:4iNHCYe1bjb/JcurXP1iGoO/2uA9606 intact-crc:2D999EA644DE9C53|rigid:6RKFej5CC8CKHhbjk/dXIOeI9Uc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NDX5 uniprotkb:Q9BUT9 intact:EBI-1223801|uniprotkb:Q5HYF0|uniprotkb:Q6NSG2|uniprotkb:Q8NFT7|uniprotkb:Q8NFZ1|uniprotkb:Q8TBM2|uniprotkb:Q9H971|uniprotkb:Q9H9I4|uniprotkb:A2RRP9|ensembl:ENSP00000420271 intact:EBI-721265|uniprotkb:Q969E9|uniprotkb:Q96KV8|ensembl:ENSP00000305138 psi-mi:phc3_human(display_long)|uniprotkb:PHC3(gene name)|psi-mi:PHC3(display_short)|uniprotkb:EDR3(gene name synonym)|uniprotkb:PH3(gene name synonym)|uniprotkb:Homolog of polyhomeotic 3(gene name synonym)|uniprotkb:Early development regulatory protein 3(gene name synonym) psi-mi:mcri2_human(display_long)|uniprotkb:MCRIP2(gene name)|psi-mi:MCRIP2(display_short)|uniprotkb:C16orf14(gene name synonym)|uniprotkb:FAM195A(gene name synonym)|uniprotkb:Protein FAM195A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834623|imex:IM-21659-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079223.3|refseq:NP_001295045.1|ensembl:ENSP00000420271|ensembl:ENST00000495893|ensembl:ENSP00000420294|ensembl:ENST00000497658|ensembl:ENSP00000420454|ensembl:ENSG00000173889(gene)|ensembl:ENST00000494943(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:Q8NDX5|rcsb pdb:4PZN|rcsb pdb:4PZO|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q8NDX5(identity)|entrezgene/locuslink:80012(identity)|ddbj/embl/genbank:BC131772(identity) refseq:NP_612427.2|refseq:NP_001318158.1|refseq:NP_001318159.1|ensembl:ENSG00000172366(gene)|ensembl:ENST00000307650(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010494"(cytoplasmic stress granule)|interpro:IPR029428|uniprotkb:Q9BUT9(identity)|entrezgene/locuslink:84331(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2015/12/04 rogid:hB1EMs+lCv19uuJ1O7+QiVCUoo89606 rogid:TJx/zjepOoY37UX7SmqiOjU0RPE9606 intact-crc:2D999EA644DE9C53|rigid:6RKFej5CC8CKHhbjk/dXIOeI9Uc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NDX5 uniprotkb:Q9UN30 intact:EBI-1223801|uniprotkb:Q5HYF0|uniprotkb:Q6NSG2|uniprotkb:Q8NFT7|uniprotkb:Q8NFZ1|uniprotkb:Q8TBM2|uniprotkb:Q9H971|uniprotkb:Q9H9I4|uniprotkb:A2RRP9|ensembl:ENSP00000420271 intact:EBI-6911404|ensembl:ENSP00000369380|uniprotkb:B2RA08|uniprotkb:Q5H969|uniprotkb:B0FZN6|uniprotkb:Q5H968 psi-mi:phc3_human(display_long)|uniprotkb:PHC3(gene name)|psi-mi:PHC3(display_short)|uniprotkb:EDR3(gene name synonym)|uniprotkb:PH3(gene name synonym)|uniprotkb:Homolog of polyhomeotic 3(gene name synonym)|uniprotkb:Early development regulatory protein 3(gene name synonym) psi-mi:scml1_human(display_long)|uniprotkb:SCML1(gene name)|psi-mi:SCML1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834623|imex:IM-21659-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079223.3|refseq:NP_001295045.1|ensembl:ENSP00000420271|ensembl:ENST00000495893|ensembl:ENSP00000420294|ensembl:ENST00000497658|ensembl:ENSP00000420454|ensembl:ENSG00000173889(gene)|ensembl:ENST00000494943(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:Q8NDX5|rcsb pdb:4PZN|rcsb pdb:4PZO|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q8NDX5(identity)|entrezgene/locuslink:80012(identity)|ddbj/embl/genbank:BC131772(identity) ensembl:ENSG00000047634(gene)|ensembl:ENST00000380041(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q9UN30|refseq:XP_016885212.1|refseq:XP_006724571.1|refseq:NP_001032624.1|refseq:NP_001032625.1|refseq:NP_001032629.1|refseq:NP_006737.2|uniprotkb:Q9UN30(identity)|entrezgene/locuslink:6322(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2015/12/04 rogid:hB1EMs+lCv19uuJ1O7+QiVCUoo89606 rogid:/eJ/2Xuw4P5GzHy1wGRxnYZ4hvY9606 intact-crc:2D999EA644DE9C53|rigid:6RKFej5CC8CKHhbjk/dXIOeI9Uc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NDX5 uniprotkb:Q9BQE3 intact:EBI-1223801|uniprotkb:Q5HYF0|uniprotkb:Q6NSG2|uniprotkb:Q8NFT7|uniprotkb:Q8NFZ1|uniprotkb:Q8TBM2|uniprotkb:Q9H971|uniprotkb:Q9H9I4|uniprotkb:A2RRP9|ensembl:ENSP00000420271 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:phc3_human(display_long)|uniprotkb:PHC3(gene name)|psi-mi:PHC3(display_short)|uniprotkb:EDR3(gene name synonym)|uniprotkb:PH3(gene name synonym)|uniprotkb:Homolog of polyhomeotic 3(gene name synonym)|uniprotkb:Early development regulatory protein 3(gene name synonym) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834623|imex:IM-21659-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079223.3|refseq:NP_001295045.1|ensembl:ENSP00000420271|ensembl:ENST00000495893|ensembl:ENSP00000420294|ensembl:ENST00000497658|ensembl:ENSP00000420454|ensembl:ENSG00000173889(gene)|ensembl:ENST00000494943(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:Q8NDX5|rcsb pdb:4PZN|rcsb pdb:4PZO|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q8NDX5(identity)|entrezgene/locuslink:80012(identity)|ddbj/embl/genbank:BC131772(identity) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1|uniprotkb:Q9BQE3(identity)|entrezgene/locuslink:84790(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2015/12/04 rogid:hB1EMs+lCv19uuJ1O7+QiVCUoo89606 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:2D999EA644DE9C53|rigid:6RKFej5CC8CKHhbjk/dXIOeI9Uc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NDX5 uniprotkb:O00257 intact:EBI-1223801|uniprotkb:Q5HYF0|uniprotkb:Q6NSG2|uniprotkb:Q8NFT7|uniprotkb:Q8NFZ1|uniprotkb:Q8TBM2|uniprotkb:Q9H971|uniprotkb:Q9H9I4|uniprotkb:A2RRP9|ensembl:ENSP00000420271 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 psi-mi:phc3_human(display_long)|uniprotkb:PHC3(gene name)|psi-mi:PHC3(display_short)|uniprotkb:EDR3(gene name synonym)|uniprotkb:PH3(gene name synonym)|uniprotkb:Homolog of polyhomeotic 3(gene name synonym)|uniprotkb:Early development regulatory protein 3(gene name synonym) psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834623|imex:IM-21659-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079223.3|refseq:NP_001295045.1|ensembl:ENSP00000420271|ensembl:ENST00000495893|ensembl:ENSP00000420294|ensembl:ENST00000497658|ensembl:ENSP00000420454|ensembl:ENSG00000173889(gene)|ensembl:ENST00000494943(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:Q8NDX5|rcsb pdb:4PZN|rcsb pdb:4PZO|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q8NDX5(identity)|entrezgene/locuslink:80012(identity)|ddbj/embl/genbank:BC131772(identity) refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|uniprotkb:O00257(identity)|entrezgene/locuslink:8535(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2015/12/04 rogid:hB1EMs+lCv19uuJ1O7+QiVCUoo89606 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 intact-crc:2D999EA644DE9C53|rigid:6RKFej5CC8CKHhbjk/dXIOeI9Uc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NDX5 uniprotkb:Q06587 intact:EBI-1223801|uniprotkb:Q5HYF0|uniprotkb:Q6NSG2|uniprotkb:Q8NFT7|uniprotkb:Q8NFZ1|uniprotkb:Q8TBM2|uniprotkb:Q9H971|uniprotkb:Q9H9I4|uniprotkb:A2RRP9|ensembl:ENSP00000420271 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 psi-mi:phc3_human(display_long)|uniprotkb:PHC3(gene name)|psi-mi:PHC3(display_short)|uniprotkb:EDR3(gene name synonym)|uniprotkb:PH3(gene name synonym)|uniprotkb:Homolog of polyhomeotic 3(gene name synonym)|uniprotkb:Early development regulatory protein 3(gene name synonym) psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834623|imex:IM-21659-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079223.3|refseq:NP_001295045.1|ensembl:ENSP00000420271|ensembl:ENST00000495893|ensembl:ENSP00000420294|ensembl:ENST00000497658|ensembl:ENSP00000420454|ensembl:ENSG00000173889(gene)|ensembl:ENST00000494943(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:Q8NDX5|rcsb pdb:4PZN|rcsb pdb:4PZO|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q8NDX5(identity)|entrezgene/locuslink:80012(identity)|ddbj/embl/genbank:BC131772(identity) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2015/12/04 rogid:hB1EMs+lCv19uuJ1O7+QiVCUoo89606 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 intact-crc:2D999EA644DE9C53|rigid:6RKFej5CC8CKHhbjk/dXIOeI9Uc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NDX5 uniprotkb:P20700 intact:EBI-1223801|uniprotkb:Q5HYF0|uniprotkb:Q6NSG2|uniprotkb:Q8NFT7|uniprotkb:Q8NFZ1|uniprotkb:Q8TBM2|uniprotkb:Q9H971|uniprotkb:Q9H9I4|uniprotkb:A2RRP9|ensembl:ENSP00000420271 intact:EBI-968218|ensembl:ENSP00000261366|uniprotkb:Q3SYN7|uniprotkb:Q96EI6|uniprotkb:B2R6J6 psi-mi:phc3_human(display_long)|uniprotkb:PHC3(gene name)|psi-mi:PHC3(display_short)|uniprotkb:EDR3(gene name synonym)|uniprotkb:PH3(gene name synonym)|uniprotkb:Homolog of polyhomeotic 3(gene name synonym)|uniprotkb:Early development regulatory protein 3(gene name synonym) psi-mi:lmnb1_human(display_long)|uniprotkb:LMNB1(gene name)|psi-mi:LMNB1(display_short)|uniprotkb:LMN2(gene name synonym)|uniprotkb:LMNB(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834623|imex:IM-21659-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079223.3|refseq:NP_001295045.1|ensembl:ENSP00000420271|ensembl:ENST00000495893|ensembl:ENSP00000420294|ensembl:ENST00000497658|ensembl:ENSP00000420454|ensembl:ENSG00000173889(gene)|ensembl:ENST00000494943(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:Q8NDX5|rcsb pdb:4PZN|rcsb pdb:4PZO|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q8NDX5(identity)|entrezgene/locuslink:80012(identity)|ddbj/embl/genbank:BC131772(identity) ensembl:ENSG00000113368(gene)|ensembl:ENST00000261366(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043274"(phospholipase binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:P20700|rcsb pdb:2KPW|go:"GO:0005654"(nucleoplasm)|rcsb pdb:3JT0|rcsb pdb:3TYY|rcsb pdb:3UMN|rcsb pdb:5VVX|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|reactome:R-HSA-2559584|reactome:R-HSA-1221632|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-352238|reactome:R-HSA-4419969|reactome:R-HSA-8862803|reactome:R-HSA-8950505|reactome:R-HSA-9013405|reactome:R-HSA-9035034|refseq:NP_005564.1|dip:DIP-34897N|uniprotkb:P20700(identity)|entrezgene/locuslink:4001(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2015/12/04 rogid:hB1EMs+lCv19uuJ1O7+QiVCUoo89606 rogid:ZLv4OS5VSmn3sdXB9IP98YdQ+Iw9606 intact-crc:2D999EA644DE9C53|rigid:6RKFej5CC8CKHhbjk/dXIOeI9Uc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NDX5 uniprotkb:P23396 intact:EBI-1223801|uniprotkb:Q5HYF0|uniprotkb:Q6NSG2|uniprotkb:Q8NFT7|uniprotkb:Q8NFZ1|uniprotkb:Q8TBM2|uniprotkb:Q9H971|uniprotkb:Q9H9I4|uniprotkb:A2RRP9|ensembl:ENSP00000420271 intact:EBI-351193|uniprotkb:Q498B5|uniprotkb:Q8NI95|uniprotkb:B2R7N5|ensembl:ENSP00000433821|ensembl:ENSP00000434643|ensembl:ENSP00000436971|uniprotkb:J3KN86 psi-mi:phc3_human(display_long)|uniprotkb:PHC3(gene name)|psi-mi:PHC3(display_short)|uniprotkb:EDR3(gene name synonym)|uniprotkb:PH3(gene name synonym)|uniprotkb:Homolog of polyhomeotic 3(gene name synonym)|uniprotkb:Early development regulatory protein 3(gene name synonym) psi-mi:rs3_human(display_long)|uniprotkb:RPS3(gene name)|psi-mi:RPS3(display_short)|uniprotkb:Small ribosomal subunit protein uS3(gene name synonym)|uniprotkb:OK/SW-cl.26(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834623|imex:IM-21659-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079223.3|refseq:NP_001295045.1|ensembl:ENSP00000420271|ensembl:ENST00000495893|ensembl:ENSP00000420294|ensembl:ENST00000497658|ensembl:ENSP00000420454|ensembl:ENSG00000173889(gene)|ensembl:ENST00000494943(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:Q8NDX5|rcsb pdb:4PZN|rcsb pdb:4PZO|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q8NDX5(identity)|entrezgene/locuslink:80012(identity)|ddbj/embl/genbank:BC131772(identity) refseq:NP_000996.2|ensembl:ENSG00000149273(gene)|ensembl:ENST00000524851(transcript)|ensembl:ENST00000527446(transcript)|ensembl:ENST00000531188(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032357"(oxidized purine DNA binding)|go:"GO:0032358"(oxidized pyrimidine DNA binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045738"(negative regulation of DNA repair)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061481"(response to TNF agonist)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902546"(positive regulation of DNA N-glycosylase activity)|go:"GO:1905053"(positive regulation of base-excision repair)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001272"(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001351(Ribosomal protein S3, C-terminal)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR004044(K Homology, type 2)|go:"GO:0070301"(cellular response to hydrogen peroxide)|interpro:IPR005703(Ribosomal protein S3, eukaryotic/archaeal)|go:"GO:0071159"(NF-kappaB complex)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR015946(K homology-like, alpha/beta)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR018280|interpro:IPR036419|mint:P23396|rcsb pdb:1WH9|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|go:"GO:0072686"(mitotic spindle)|go:"GO:0097100"(supercoiled DNA binding)|rcsb pdb:6QZP|go:"GO:0140078"("class I DNA-(apurinic or apyrimidinic site) endonuclease activity")|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|refseq:NP_001243731.1|refseq:NP_001247436.1|refseq:NP_001247435.1|dip:DIP-33177N|uniprotkb:P23396(identity)|entrezgene/locuslink:6188(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2015/12/04 rogid:hB1EMs+lCv19uuJ1O7+QiVCUoo89606 rogid:fsDW18AMR3YyEEIhMVcngYRWkps9606 intact-crc:2D999EA644DE9C53|rigid:6RKFej5CC8CKHhbjk/dXIOeI9Uc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NDX5 uniprotkb:P04637 intact:EBI-1223801|uniprotkb:Q5HYF0|uniprotkb:Q6NSG2|uniprotkb:Q8NFT7|uniprotkb:Q8NFZ1|uniprotkb:Q8TBM2|uniprotkb:Q9H971|uniprotkb:Q9H9I4|uniprotkb:A2RRP9|ensembl:ENSP00000420271 intact:EBI-366083|uniprotkb:Q15086|uniprotkb:Q15087|uniprotkb:Q15088|uniprotkb:Q16535|uniprotkb:Q16807|uniprotkb:Q16808|uniprotkb:Q16809|uniprotkb:Q16810|uniprotkb:Q16811|uniprotkb:Q16848|uniprotkb:Q86UG1|uniprotkb:Q8J016|uniprotkb:Q99659|uniprotkb:Q9BTM4|uniprotkb:Q9HAQ8|uniprotkb:Q9NP68|uniprotkb:Q9NPJ2|uniprotkb:Q9NZD0|uniprotkb:Q9UBI2|uniprotkb:Q9UQ61|ensembl:ENSP00000269305|ensembl:ENSP00000391478|intact:EBI-28980681|uniprotkb:Q2XN98|uniprotkb:Q3LRW1|uniprotkb:Q3LRW2|uniprotkb:Q3LRW3|uniprotkb:Q3LRW4|uniprotkb:Q3LRW5 psi-mi:phc3_human(display_long)|uniprotkb:PHC3(gene name)|psi-mi:PHC3(display_short)|uniprotkb:EDR3(gene name synonym)|uniprotkb:PH3(gene name synonym)|uniprotkb:Homolog of polyhomeotic 3(gene name synonym)|uniprotkb:Early development regulatory protein 3(gene name synonym) psi-mi:p53_human(display_long)|uniprotkb:TP53(gene name)|psi-mi:TP53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym)|uniprotkb:Phosphoprotein p53(gene name synonym)|uniprotkb:Antigen NY-CO-13(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834623|imex:IM-21659-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079223.3|refseq:NP_001295045.1|ensembl:ENSP00000420271|ensembl:ENST00000495893|ensembl:ENSP00000420294|ensembl:ENST00000497658|ensembl:ENSP00000420454|ensembl:ENSG00000173889(gene)|ensembl:ENST00000494943(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:Q8NDX5|rcsb pdb:4PZN|rcsb pdb:4PZO|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q8NDX5(identity)|entrezgene/locuslink:80012(identity)|ddbj/embl/genbank:BC131772(identity) refseq:NP_001263624.1|refseq:NP_001263625.1|ensembl:ENSG00000141510(gene)|ensembl:ENST00000269305(transcript)|ensembl:ENST00000445888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0002020"(protease binding)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0031497"(chromatin assembly)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034103"(regulation of tissue remodeling)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035033"(histone deacetylase regulator activity)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035690"|go:"GO:0035794"(positive regulation of mitochondrial membrane permeability)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0006983"(ER overload response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007369"(gastrulation)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0043621"(protein self-association)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048512"(circadian behavior)|go:"GO:0048539"(bone marrow development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062100"(positive regulation of programmed necrotic cell death)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071494"(cellular response to UV-C)|go:"GO:0072331"(signal transduction by p53 class mediator)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:0090399"(replicative senescence)|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097252"(oligodendrocyte apoptotic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1902253"(regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904024"(negative regulation of glucose catabolic process to lactate via pyruvate)|go:"GO:1905856"(negative regulation of pentose-phosphate shunt)|go:"GO:1990144"(intrinsic apoptotic signaling pathway in response to hypoxia)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000269"(regulation of fibroblast apoptotic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009299"(mRNA transcription)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009651"(response to salt stress)|go:"GO:0010165"(response to X-ray)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016032"(viral process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013872("p53 transactivation domain (TAD)")|interpro:IPR036674|interpro:IPR040926|rcsb pdb:2ATA|rcsb pdb:2B3G|rcsb pdb:2BIM|rcsb pdb:2BIN|rcsb pdb:2BIO|rcsb pdb:2BIP|rcsb pdb:2AHI|rcsb pdb:2BIQ|rcsb pdb:2F1X|rcsb pdb:2FEJ|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2GS0|rcsb pdb:2H1L|rcsb pdb:2H2D|rcsb pdb:2H2F|rcsb pdb:2H4F|rcsb pdb:2H4H|rcsb pdb:2H4J|rcsb pdb:2H59|rcsb pdb:2J0Z|rcsb pdb:2J10|rcsb pdb:2J11|rcsb pdb:2J1W|rcsb pdb:2J1X|rcsb pdb:2J1Y|rcsb pdb:2J1Z|rcsb pdb:2J20|rcsb pdb:2J21|rcsb pdb:2K8F|rcsb pdb:2L14|rcsb pdb:2LY4|rcsb pdb:2MEJ|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:2MWY|rcsb pdb:2MZD|rcsb pdb:2OCJ|rcsb pdb:2PCX|rcsb pdb:1A1U|rcsb pdb:1AIE|rcsb pdb:1C26|rcsb pdb:1DT7|rcsb pdb:1GZH|rcsb pdb:1H26|rcsb pdb:1HS5|rcsb pdb:1JSP|rcsb pdb:1KZY|rcsb pdb:1MA3|rcsb pdb:1OLG|rcsb pdb:1OLH|rcsb pdb:1PES|rcsb pdb:1PET|mint:P04637|rcsb pdb:1SAE|rcsb pdb:1SAF|rcsb pdb:1SAK|rcsb pdb:1SAL|rcsb pdb:1TSR|rcsb pdb:1TUP|rcsb pdb:1UOL|rcsb pdb:1XQH|rcsb pdb:1YC5|rcsb pdb:1YCQ|rcsb pdb:1YCR|rcsb pdb:1YCS|rcsb pdb:2AC0|rcsb pdb:2ADY|refseq:NP_000537.3|refseq:NP_001119584.1|refseq:NP_001119585.1|refseq:NP_001119586.1|refseq:NP_001119587.1|refseq:NP_001119588.1|refseq:NP_001119589.1|rcsb pdb:2RUK|rcsb pdb:2VUK|rcsb pdb:3Q06|rcsb pdb:2WGX|rcsb pdb:2X0U|rcsb pdb:2X0V|rcsb pdb:2X0W|rcsb pdb:2XWR|rcsb pdb:2YBG|rcsb pdb:2YDR|rcsb pdb:2Z5S|rcsb pdb:2Z5T|rcsb pdb:3SAK|rcsb pdb:3D05|rcsb pdb:3D06|rcsb pdb:3D07|rcsb pdb:3D08|rcsb pdb:3D09|rcsb pdb:3D0A|rcsb pdb:3DAB|rcsb pdb:3DAC|rcsb pdb:3IGK|rcsb pdb:3IGL|rcsb pdb:3KMD|rcsb pdb:3TG5|rcsb pdb:3KZ8|rcsb pdb:3LW1|rcsb pdb:3OQ5|rcsb pdb:3PDH|rcsb pdb:3Q01|rcsb pdb:3Q05|rcsb pdb:3TS8|rcsb pdb:3ZME|rcsb pdb:4AGM|rcsb pdb:4AGN|rcsb pdb:4AGO|rcsb pdb:4AGP|rcsb pdb:4AGQ|rcsb pdb:4BUZ|rcsb pdb:4BV2|rcsb pdb:4HFZ|rcsb pdb:4HJE|rcsb pdb:4IBQ|rcsb pdb:4IBS|rcsb pdb:4IBT|rcsb pdb:4IBU|rcsb pdb:4IBV|rcsb pdb:4IBW|rcsb pdb:4IBY|rcsb pdb:4IBZ|rcsb pdb:4IJT|rcsb pdb:4KVP|rcsb pdb:4LO9|rcsb pdb:4LOE|rcsb pdb:4LOF|rcsb pdb:4MZI|rcsb pdb:4MZR|rcsb pdb:4QO1|rcsb pdb:4RP6|rcsb pdb:4RP7|rcsb pdb:4X34|rcsb pdb:4XR8|rcsb pdb:4ZZJ|rcsb pdb:5A7B|rcsb pdb:5AB9|rcsb pdb:5ABA|rcsb pdb:4AGL|rcsb pdb:5AOI|rcsb pdb:5AOJ|rcsb pdb:5AOK|rcsb pdb:5AOL|rcsb pdb:5AOM|rcsb pdb:6XRE|rcsb pdb:7BWN|rcsb pdb:7DHY|rcsb pdb:7DHZ|rcsb pdb:7EL4|reactome:R-HSA-111448|reactome:R-HSA-139915|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-2559586|reactome:R-HSA-3232118|reactome:R-HSA-349425|reactome:R-HSA-390471|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5693565|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804114|reactome:R-HSA-6804115|reactome:R-HSA-6804116|reactome:R-HSA-6804754|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-69473|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8853884|reactome:R-HSA-8941855|reactome:R-HSA-8943724|reactome:R-HSA-983231|rcsb pdb:5ECG|rcsb pdb:5G4M|rcsb pdb:5G4N|rcsb pdb:5BUA|rcsb pdb:5G4O|rcsb pdb:5HOU|rcsb pdb:5HP0|rcsb pdb:5HPD|rcsb pdb:5LAP|rcsb pdb:5LGY|rcsb pdb:5MCT|rcsb pdb:5MCU|rcsb pdb:5MCV|rcsb pdb:5MCW|rcsb pdb:5MF7|rcsb pdb:5MG7|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5O1A|rcsb pdb:5O1B|rcsb pdb:5O1C|rcsb pdb:5O1D|rcsb pdb:5O1E|rcsb pdb:5O1F|rcsb pdb:5O1G|rcsb pdb:5O1H|rcsb pdb:5O1I|rcsb pdb:5OL0|rcsb pdb:5UN8|rcsb pdb:5XZC|rcsb pdb:6FF9|rcsb pdb:6FJ5|rcsb pdb:6GGA|rcsb pdb:6GGB|rcsb pdb:6GGC|rcsb pdb:6GGD|rcsb pdb:6GGE|rcsb pdb:6GGF|rcsb pdb:6LHD|rcsb pdb:6R5L|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:6RWS|rcsb pdb:6RWU|rcsb pdb:6RX2|rcsb pdb:6RZ3|rcsb pdb:6S39|rcsb pdb:6S40|rcsb pdb:6S9Q|rcsb pdb:6SHZ|rcsb pdb:6SI0|rcsb pdb:6SI1|rcsb pdb:6SI2|rcsb pdb:6SI3|rcsb pdb:6SI4|rcsb pdb:6SIN|rcsb pdb:6SIO|rcsb pdb:6SIP|rcsb pdb:6SIQ|rcsb pdb:6SL6|rcsb pdb:6SLV|rcsb pdb:6T58|rcsb pdb:6V4F|rcsb pdb:6V4H|rcsb pdb:6VQO|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6S3C|ensembl:ENSP00000269305|ensembl:ENST00000420246|ensembl:ENSP00000391127|ensembl:ENSP00000391478|ensembl:ENST00000455263|ensembl:ENSP00000398846|ensembl:ENST00000504290|ensembl:ENSP00000484409|ensembl:ENST00000504937|ensembl:ENSP00000481179|ensembl:ENST00000510385|ensembl:ENSP00000478499|ensembl:ENST00000610292|ensembl:ENSP00000478219|ensembl:ENST00000610538|ensembl:ENSP00000480868|ensembl:ENST00000619485|ensembl:ENSP00000482537|ensembl:ENST00000620739|ensembl:ENSP00000481638|ensembl:ENST00000622645|ensembl:ENSP00000482222|refseq:NP_001119590.1|refseq:NP_001263626.1|refseq:NP_001263627.1|refseq:NP_001263628.1|refseq:NP_001263689.1|refseq:NP_001263690.1|dip:DIP-368N|uniprotkb:P04637(identity)|entrezgene/locuslink:7157(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2015/12/04 rogid:hB1EMs+lCv19uuJ1O7+QiVCUoo89606 rogid:fGN3kSCGIpi/D6d/X5kaB0Xu8/k9606 intact-crc:2D999EA644DE9C53|rigid:6RKFej5CC8CKHhbjk/dXIOeI9Uc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NDX5 uniprotkb:Q7Z417 intact:EBI-1223801|uniprotkb:Q5HYF0|uniprotkb:Q6NSG2|uniprotkb:Q8NFT7|uniprotkb:Q8NFZ1|uniprotkb:Q8TBM2|uniprotkb:Q9H971|uniprotkb:Q9H9I4|uniprotkb:A2RRP9|ensembl:ENSP00000420271 intact:EBI-1210753|intact:EBI-10172018|uniprotkb:A1L3A7|uniprotkb:Q9P2M5|uniprotkb:A1L3A6|ensembl:ENSP00000225388 psi-mi:phc3_human(display_long)|uniprotkb:PHC3(gene name)|psi-mi:PHC3(display_short)|uniprotkb:EDR3(gene name synonym)|uniprotkb:PH3(gene name synonym)|uniprotkb:Homolog of polyhomeotic 3(gene name synonym)|uniprotkb:Early development regulatory protein 3(gene name synonym) psi-mi:nufp2_human(display_long)|uniprotkb:NUFIP2(gene name)|psi-mi:NUFIP2(display_short)|uniprotkb:KIAA1321(gene name synonym)|uniprotkb:PIG1(orf name)|uniprotkb:FMRP-interacting protein 2(gene name synonym)|uniprotkb:82 kDa FMRP-interacting protein(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 1 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834623|imex:IM-21659-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079223.3|refseq:NP_001295045.1|ensembl:ENSP00000420271|ensembl:ENST00000495893|ensembl:ENSP00000420294|ensembl:ENST00000497658|ensembl:ENSP00000420454|ensembl:ENSG00000173889(gene)|ensembl:ENST00000494943(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:Q8NDX5|rcsb pdb:4PZN|rcsb pdb:4PZO|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q8NDX5(identity)|entrezgene/locuslink:80012(identity)|ddbj/embl/genbank:BC131772(identity) refseq:NP_065823.1|dip:DIP-29023N|ensembl:ENSG00000108256(gene)|ensembl:ENST00000225388(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR032747|mint:Q7Z417|uniprotkb:Q7Z417(identity)|entrezgene/locuslink:57532(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2015/12/04 rogid:hB1EMs+lCv19uuJ1O7+QiVCUoo89606 rogid:zdbkRisveP+8g70umfbEPHTnAgk9606 intact-crc:2D999EA644DE9C53|rigid:6RKFej5CC8CKHhbjk/dXIOeI9Uc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NDX5 uniprotkb:Q03252 intact:EBI-1223801|uniprotkb:Q5HYF0|uniprotkb:Q6NSG2|uniprotkb:Q8NFT7|uniprotkb:Q8NFZ1|uniprotkb:Q8TBM2|uniprotkb:Q9H971|uniprotkb:Q9H9I4|uniprotkb:A2RRP9|ensembl:ENSP00000420271 intact:EBI-2830427|uniprotkb:O75292|uniprotkb:Q14734|uniprotkb:Q96DF6|ensembl:ENSP00000327054|intact:EBI-11044751|intact:EBI-20728818 psi-mi:phc3_human(display_long)|uniprotkb:PHC3(gene name)|psi-mi:PHC3(display_short)|uniprotkb:EDR3(gene name synonym)|uniprotkb:PH3(gene name synonym)|uniprotkb:Homolog of polyhomeotic 3(gene name synonym)|uniprotkb:Early development regulatory protein 3(gene name synonym) psi-mi:lmnb2_human(display_long)|uniprotkb:LMNB2(gene name)|psi-mi:LMNB2(display_short)|uniprotkb:LMN2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834623|imex:IM-21659-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079223.3|refseq:NP_001295045.1|ensembl:ENSP00000420271|ensembl:ENST00000495893|ensembl:ENSP00000420294|ensembl:ENST00000497658|ensembl:ENSP00000420454|ensembl:ENSG00000173889(gene)|ensembl:ENST00000494943(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:Q8NDX5|rcsb pdb:4PZN|rcsb pdb:4PZO|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q8NDX5(identity)|entrezgene/locuslink:80012(identity)|ddbj/embl/genbank:BC131772(identity) ensembl:ENSG00000176619(gene)|ensembl:ENST00000325327(transcript)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005882"(intermediate filament)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:Q03252|rcsb pdb:2LLL|rcsb pdb:5BNW|refseq:NP_116126.3|dip:DIP-57724N|uniprotkb:Q03252(identity)|entrezgene/locuslink:84823(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2015/12/04 rogid:hB1EMs+lCv19uuJ1O7+QiVCUoo89606 rogid:Jt7rEo5Br8HidU+VAc0L6rtBU889606 intact-crc:2D999EA644DE9C53|rigid:6RKFej5CC8CKHhbjk/dXIOeI9Uc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NDX5 uniprotkb:P35227 intact:EBI-1223801|uniprotkb:Q5HYF0|uniprotkb:Q6NSG2|uniprotkb:Q8NFT7|uniprotkb:Q8NFZ1|uniprotkb:Q8TBM2|uniprotkb:Q9H971|uniprotkb:Q9H9I4|uniprotkb:A2RRP9|ensembl:ENSP00000420271 intact:EBI-2129767|uniprotkb:A6NGD8|ensembl:ENSP00000478517|ensembl:ENSP00000478970|ensembl:ENSP00000482063|ensembl:ENSP00000482815|ensembl:ENSP00000488868|ensembl:ENSP00000488872 psi-mi:phc3_human(display_long)|uniprotkb:PHC3(gene name)|psi-mi:PHC3(display_short)|uniprotkb:EDR3(gene name synonym)|uniprotkb:PH3(gene name synonym)|uniprotkb:Homolog of polyhomeotic 3(gene name synonym)|uniprotkb:Early development regulatory protein 3(gene name synonym) psi-mi:pcgf2_human(display_long)|uniprotkb:PCGF2(gene name)|psi-mi:PCGF2(display_short)|uniprotkb:MEL18(gene name synonym)|uniprotkb:RNF110(gene name synonym)|uniprotkb:ZNF144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834623|imex:IM-21659-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079223.3|refseq:NP_001295045.1|ensembl:ENSP00000420271|ensembl:ENST00000495893|ensembl:ENSP00000420294|ensembl:ENST00000497658|ensembl:ENSP00000420454|ensembl:ENSG00000173889(gene)|ensembl:ENST00000494943(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:Q8NDX5|rcsb pdb:4PZN|rcsb pdb:4PZO|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q8NDX5(identity)|entrezgene/locuslink:80012(identity)|ddbj/embl/genbank:BC131772(identity) refseq:NP_009075.1|refseq:XP_016880505.1|refseq:XP_005257697.1|refseq:XP_005257698.1|refseq:XP_005257699.1|dip:DIP-41880N|ensembl:ENSG00000277258(gene)|ensembl:ENSG00000278644(gene)|ensembl:ENST00000610440(transcript)|ensembl:ENST00000611883(transcript)|ensembl:ENST00000616199(transcript)|ensembl:ENST00000620225(transcript)|ensembl:ENST00000631566(transcript)|ensembl:ENST00000631610(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35227|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-5617472|reactome:R-HSA-8953750|uniprotkb:P35227(identity)|entrezgene/locuslink:7703(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2015/12/04 rogid:hB1EMs+lCv19uuJ1O7+QiVCUoo89606 rogid:zppw56VrEl6gEFwtJMCN5cQkPxI9606 intact-crc:2D999EA644DE9C53|rigid:6RKFej5CC8CKHhbjk/dXIOeI9Uc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NDX5 uniprotkb:Q14781 intact:EBI-1223801|uniprotkb:Q5HYF0|uniprotkb:Q6NSG2|uniprotkb:Q8NFT7|uniprotkb:Q8NFZ1|uniprotkb:Q8TBM2|uniprotkb:Q9H971|uniprotkb:Q9H9I4|uniprotkb:A2RRP9|ensembl:ENSP00000420271 intact:EBI-745934|uniprotkb:Q9BTB1|uniprotkb:Q0VDA5|ensembl:ENSP00000308750 psi-mi:phc3_human(display_long)|uniprotkb:PHC3(gene name)|psi-mi:PHC3(display_short)|uniprotkb:EDR3(gene name synonym)|uniprotkb:PH3(gene name synonym)|uniprotkb:Homolog of polyhomeotic 3(gene name synonym)|uniprotkb:Early development regulatory protein 3(gene name synonym) psi-mi:cbx2_human(display_long)|uniprotkb:CBX2(gene name)|psi-mi:CBX2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834623|imex:IM-21659-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079223.3|refseq:NP_001295045.1|ensembl:ENSP00000420271|ensembl:ENST00000495893|ensembl:ENSP00000420294|ensembl:ENST00000497658|ensembl:ENSP00000420454|ensembl:ENSG00000173889(gene)|ensembl:ENST00000494943(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:Q8NDX5|rcsb pdb:4PZN|rcsb pdb:4PZO|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q8NDX5(identity)|entrezgene/locuslink:80012(identity)|ddbj/embl/genbank:BC131772(identity) refseq:NP_005180.1|refseq:NP_116036.1|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|go:"GO:0045137"(development of primary sexual characteristics)|interpro:IPR042796|mint:Q14781|rcsb pdb:2D9U|rcsb pdb:3H91|rcsb pdb:5EPK|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSG00000173894(gene)|ensembl:ENST00000310942(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|dip:DIP-48604N|uniprotkb:Q14781(identity)|entrezgene/locuslink:84733(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2015/12/04 rogid:hB1EMs+lCv19uuJ1O7+QiVCUoo89606 rogid:220eC8UGlmAHHP2WAhZdAveHC3s9606 intact-crc:2D999EA644DE9C53|rigid:6RKFej5CC8CKHhbjk/dXIOeI9Uc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NDX5 uniprotkb:O95931 intact:EBI-1223801|uniprotkb:Q5HYF0|uniprotkb:Q6NSG2|uniprotkb:Q8NFT7|uniprotkb:Q8NFZ1|uniprotkb:Q8TBM2|uniprotkb:Q9H971|uniprotkb:Q9H9I4|uniprotkb:A2RRP9|ensembl:ENSP00000420271 intact:EBI-3923843|uniprotkb:Q86T17|ensembl:ENSP00000216133 psi-mi:phc3_human(display_long)|uniprotkb:PHC3(gene name)|psi-mi:PHC3(display_short)|uniprotkb:EDR3(gene name synonym)|uniprotkb:PH3(gene name synonym)|uniprotkb:Homolog of polyhomeotic 3(gene name synonym)|uniprotkb:Early development regulatory protein 3(gene name synonym) psi-mi:cbx7_human(display_long)|uniprotkb:CBX7(gene name)|psi-mi:CBX7(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834623|imex:IM-21659-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079223.3|refseq:NP_001295045.1|ensembl:ENSP00000420271|ensembl:ENST00000495893|ensembl:ENSP00000420294|ensembl:ENST00000497658|ensembl:ENSP00000420454|ensembl:ENSG00000173889(gene)|ensembl:ENST00000494943(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:Q8NDX5|rcsb pdb:4PZN|rcsb pdb:4PZO|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q8NDX5(identity)|entrezgene/locuslink:80012(identity)|ddbj/embl/genbank:BC131772(identity) refseq:NP_783640.1|ensembl:ENSG00000100307(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|mint:O95931|rcsb pdb:2K1B|rcsb pdb:2L12|rcsb pdb:2L1B|rcsb pdb:3GS2|rcsb pdb:4MN3|rcsb pdb:5EPJ|rcsb pdb:6V2R|ensembl:ENST00000216133(transcript)|dip:DIP-44565N|uniprotkb:O95931(identity)|entrezgene/locuslink:23492(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2015/12/04 rogid:hB1EMs+lCv19uuJ1O7+QiVCUoo89606 rogid:LDXV9srMj1BL2CaSSot1Bn0/EW49606 intact-crc:2D999EA644DE9C53|rigid:6RKFej5CC8CKHhbjk/dXIOeI9Uc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NDX5 uniprotkb:Q9HC52 intact:EBI-1223801|uniprotkb:Q5HYF0|uniprotkb:Q6NSG2|uniprotkb:Q8NFT7|uniprotkb:Q8NFZ1|uniprotkb:Q8TBM2|uniprotkb:Q9H971|uniprotkb:Q9H9I4|uniprotkb:A2RRP9|ensembl:ENSP00000420271 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 psi-mi:phc3_human(display_long)|uniprotkb:PHC3(gene name)|psi-mi:PHC3(display_short)|uniprotkb:EDR3(gene name synonym)|uniprotkb:PH3(gene name synonym)|uniprotkb:Homolog of polyhomeotic 3(gene name synonym)|uniprotkb:Early development regulatory protein 3(gene name synonym) psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834623|imex:IM-21659-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079223.3|refseq:NP_001295045.1|ensembl:ENSP00000420271|ensembl:ENST00000495893|ensembl:ENSP00000420294|ensembl:ENST00000497658|ensembl:ENSP00000420454|ensembl:ENSG00000173889(gene)|ensembl:ENST00000494943(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:Q8NDX5|rcsb pdb:4PZN|rcsb pdb:4PZO|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q8NDX5(identity)|entrezgene/locuslink:80012(identity)|ddbj/embl/genbank:BC131772(identity) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N|uniprotkb:Q9HC52(identity)|entrezgene/locuslink:57332(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2015/12/04 rogid:hB1EMs+lCv19uuJ1O7+QiVCUoo89606 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 intact-crc:2D999EA644DE9C53|rigid:6RKFej5CC8CKHhbjk/dXIOeI9Uc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NDX5 uniprotkb:P35226 intact:EBI-1223801|uniprotkb:Q5HYF0|uniprotkb:Q6NSG2|uniprotkb:Q8NFT7|uniprotkb:Q8NFZ1|uniprotkb:Q8TBM2|uniprotkb:Q9H971|uniprotkb:Q9H9I4|uniprotkb:A2RRP9|ensembl:ENSP00000420271 intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851 psi-mi:phc3_human(display_long)|uniprotkb:PHC3(gene name)|psi-mi:PHC3(display_short)|uniprotkb:EDR3(gene name synonym)|uniprotkb:PH3(gene name synonym)|uniprotkb:Homolog of polyhomeotic 3(gene name synonym)|uniprotkb:Early development regulatory protein 3(gene name synonym) psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834623|imex:IM-21659-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079223.3|refseq:NP_001295045.1|ensembl:ENSP00000420271|ensembl:ENST00000495893|ensembl:ENSP00000420294|ensembl:ENST00000497658|ensembl:ENSP00000420454|ensembl:ENSG00000173889(gene)|ensembl:ENST00000494943(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:Q8NDX5|rcsb pdb:4PZN|rcsb pdb:4PZO|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q8NDX5(identity)|entrezgene/locuslink:80012(identity)|ddbj/embl/genbank:BC131772(identity) refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:P35226(identity)|entrezgene/locuslink:100532731(identity)|entrezgene/locuslink:648(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2015/12/04 rogid:hB1EMs+lCv19uuJ1O7+QiVCUoo89606 rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606 intact-crc:2D999EA644DE9C53|rigid:6RKFej5CC8CKHhbjk/dXIOeI9Uc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NDX5 uniprotkb:Q99496 intact:EBI-1223801|uniprotkb:Q5HYF0|uniprotkb:Q6NSG2|uniprotkb:Q8NFT7|uniprotkb:Q8NFZ1|uniprotkb:Q8TBM2|uniprotkb:Q9H971|uniprotkb:Q9H9I4|uniprotkb:A2RRP9|ensembl:ENSP00000420271 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:phc3_human(display_long)|uniprotkb:PHC3(gene name)|psi-mi:PHC3(display_short)|uniprotkb:EDR3(gene name synonym)|uniprotkb:PH3(gene name synonym)|uniprotkb:Homolog of polyhomeotic 3(gene name synonym)|uniprotkb:Early development regulatory protein 3(gene name synonym) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834623|imex:IM-21659-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079223.3|refseq:NP_001295045.1|ensembl:ENSP00000420271|ensembl:ENST00000495893|ensembl:ENSP00000420294|ensembl:ENST00000497658|ensembl:ENSP00000420454|ensembl:ENSG00000173889(gene)|ensembl:ENST00000494943(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:Q8NDX5|rcsb pdb:4PZN|rcsb pdb:4PZO|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q8NDX5(identity)|entrezgene/locuslink:80012(identity)|ddbj/embl/genbank:BC131772(identity) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|entrezgene/locuslink:6045(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2015/12/04 rogid:hB1EMs+lCv19uuJ1O7+QiVCUoo89606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 intact-crc:2D999EA644DE9C53|rigid:6RKFej5CC8CKHhbjk/dXIOeI9Uc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5T6S3 uniprotkb:Q14257 intact:EBI-2339674|uniprotkb:Q6N038|uniprotkb:Q32NF2|uniprotkb:Q8TBL6|uniprotkb:Q5T6S4|uniprotkb:Q9UFS9|ensembl:ENSP00000363003 intact:EBI-356710|uniprotkb:A8MTG6|uniprotkb:Q53XN8|ensembl:ENSP00000378349|uniprotkb:F8WCY5 psi-mi:phf19_human(display_long)|uniprotkb:PHF19(gene name)|psi-mi:PHF19(display_short)|uniprotkb:PCL3(gene name synonym)|uniprotkb:Polycomb-like protein 3(gene name synonym) psi-mi:rcn2_human(display_long)|uniprotkb:RCN2(gene name)|psi-mi:RCN2(display_short)|uniprotkb:ERC55(gene name synonym)|uniprotkb:Calcium-binding protein ERC-55(gene name synonym)|uniprotkb:E6-binding protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834756|imex:IM-21659-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011516811.1|refseq:NP_001009936.1|refseq:NP_056466.1|refseq:NP_001273769.1|refseq:NP_001273772.1|refseq:XP_005251963.1|refseq:XP_016870101.1|ensembl:ENSG00000119403(gene)|ensembl:ENST00000373896(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042017|mint:Q5T6S3|rcsb pdb:2E5Q|rcsb pdb:4BD3|rcsb pdb:6NQ3|rcsb pdb:6WAU|reactome:R-HSA-212300|uniprotkb:Q5T6S3(identity)|entrezgene/locuslink:26147(identity)|ddbj/embl/genbank:BC125076(identity) refseq:NP_002893.1|ensembl:ENST00000394885(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|ensembl:ENSG00000117906(gene)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q14257|refseq:NP_001258766.1|uniprotkb:Q14257(identity)|entrezgene/locuslink:5955(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:K4sKpUT1htSiigJaEoGyDjvkWqc9606 rogid:99ru/7eYUvZ5xdb+x4inbib3PP89606 intact-crc:C55F01C913B453F7|rigid:V/3af30mb9fBOZsXO1hdgP2/0Jg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5T6S3 uniprotkb:Q96JN0 intact:EBI-2339674|uniprotkb:Q6N038|uniprotkb:Q32NF2|uniprotkb:Q8TBL6|uniprotkb:Q5T6S4|uniprotkb:Q9UFS9|ensembl:ENSP00000363003 intact:EBI-746045|uniprotkb:Q9H945|uniprotkb:Q9Y457|ensembl:ENSP00000348298|ensembl:ENSP00000360138|ensembl:ENSP00000360144|ensembl:ENSP00000501560|ensembl:ENSP00000501639|ensembl:ENSP00000502633|intact:EBI-8833163|uniprotkb:D3DR47|uniprotkb:Q5VW16|uniprotkb:Q7Z723|uniprotkb:Q86T32|uniprotkb:Q86T33|uniprotkb:Q8N3L6|uniprotkb:Q8N655 psi-mi:phf19_human(display_long)|uniprotkb:PHF19(gene name)|psi-mi:PHF19(display_short)|uniprotkb:PCL3(gene name synonym)|uniprotkb:Polycomb-like protein 3(gene name synonym) psi-mi:lcor_human(display_long)|uniprotkb:LCOR(gene name)|psi-mi:LCOR(display_short)|uniprotkb:C10orf12(gene name synonym)|uniprotkb:KIAA1795(gene name synonym)|uniprotkb:MLR2(gene name synonym)|uniprotkb:Mblk1-related protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834756|imex:IM-21659-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011516811.1|refseq:NP_001009936.1|refseq:NP_056466.1|refseq:NP_001273769.1|refseq:NP_001273772.1|refseq:XP_005251963.1|refseq:XP_016870101.1|ensembl:ENSG00000119403(gene)|ensembl:ENST00000373896(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042017|mint:Q5T6S3|rcsb pdb:2E5Q|rcsb pdb:4BD3|rcsb pdb:6NQ3|rcsb pdb:6WAU|reactome:R-HSA-212300|uniprotkb:Q5T6S3(identity)|entrezgene/locuslink:26147(identity)|ddbj/embl/genbank:BC125076(identity) ensembl:ENSG00000196233(gene)|ensembl:ENST00000356016(transcript)|ensembl:ENST00000371097(transcript)|ensembl:ENST00000371103(transcript)|ensembl:ENST00000675471(transcript)|ensembl:ENST00000675537(transcript)|ensembl:ENST00000675971(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|mint:Q96JN0|rcsb pdb:2COB|refseq:NP_001164236.1|refseq:NP_001164237.1|refseq:NP_115816.2|refseq:XP_016872275.1|refseq:XP_016872276.1|refseq:XP_016872277.1|refseq:NP_001333445.1|uniprotkb:Q8N655(identity)|entrezgene/locuslink:26148(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:K4sKpUT1htSiigJaEoGyDjvkWqc9606 rogid:cOnk6EDDff86yaG1uG+dxEQ1Z689606 intact-crc:C55F01C913B453F7|rigid:V/3af30mb9fBOZsXO1hdgP2/0Jg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5T6S3 uniprotkb:Q09028 intact:EBI-2339674|uniprotkb:Q6N038|uniprotkb:Q32NF2|uniprotkb:Q8TBL6|uniprotkb:Q5T6S4|uniprotkb:Q9UFS9|ensembl:ENSP00000363003 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 psi-mi:phf19_human(display_long)|uniprotkb:PHF19(gene name)|psi-mi:PHF19(display_short)|uniprotkb:PCL3(gene name synonym)|uniprotkb:Polycomb-like protein 3(gene name synonym) psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834756|imex:IM-21659-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011516811.1|refseq:NP_001009936.1|refseq:NP_056466.1|refseq:NP_001273769.1|refseq:NP_001273772.1|refseq:XP_005251963.1|refseq:XP_016870101.1|ensembl:ENSG00000119403(gene)|ensembl:ENST00000373896(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042017|mint:Q5T6S3|rcsb pdb:2E5Q|rcsb pdb:4BD3|rcsb pdb:6NQ3|rcsb pdb:6WAU|reactome:R-HSA-212300|uniprotkb:Q5T6S3(identity)|entrezgene/locuslink:26147(identity)|ddbj/embl/genbank:BC125076(identity) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|entrezgene/locuslink:5928(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:K4sKpUT1htSiigJaEoGyDjvkWqc9606 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 intact-crc:C55F01C913B453F7|rigid:V/3af30mb9fBOZsXO1hdgP2/0Jg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5T6S3 uniprotkb:Q92800 intact:EBI-2339674|uniprotkb:Q6N038|uniprotkb:Q32NF2|uniprotkb:Q8TBL6|uniprotkb:Q5T6S4|uniprotkb:Q9UFS9|ensembl:ENSP00000363003 intact:EBI-8830732|uniprotkb:B4E3R7|uniprotkb:O43287|uniprotkb:A6NCH6|uniprotkb:Q14459|uniprotkb:Q53XP3|uniprotkb:B4DSS2|uniprotkb:B4DIJ1|uniprotkb:B4DIZ7|ensembl:ENSP00000404658|ensembl:ENSP00000466924 psi-mi:phf19_human(display_long)|uniprotkb:PHF19(gene name)|psi-mi:PHF19(display_short)|uniprotkb:PCL3(gene name synonym)|uniprotkb:Polycomb-like protein 3(gene name synonym) psi-mi:ezh1_human(display_long)|uniprotkb:ENX-2(gene name synonym)|uniprotkb:Enhancer of zeste homolog 1(gene name synonym)|uniprotkb:KIAA0388(gene name synonym)|uniprotkb:EZH1(gene name)|psi-mi:EZH1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834756|imex:IM-21659-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011516811.1|refseq:NP_001009936.1|refseq:NP_056466.1|refseq:NP_001273769.1|refseq:NP_001273772.1|refseq:XP_005251963.1|refseq:XP_016870101.1|ensembl:ENSG00000119403(gene)|ensembl:ENST00000373896(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042017|mint:Q5T6S3|rcsb pdb:2E5Q|rcsb pdb:4BD3|rcsb pdb:6NQ3|rcsb pdb:6WAU|reactome:R-HSA-212300|uniprotkb:Q5T6S3(identity)|entrezgene/locuslink:26147(identity)|ddbj/embl/genbank:BC125076(identity) refseq:NP_001308008.1|refseq:NP_001308010.1|refseq:NP_001308011.1|refseq:NP_001982.2|dip:DIP-58580N|ensembl:ENSG00000108799(gene)|ensembl:ENST00000428826(transcript)|ensembl:ENST00000592743(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0021766"(hippocampus development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0031507"(heterochromatin assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR021654|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR032926|interpro:IPR041343|interpro:IPR041355|interpro:IPR044438|mint:Q92800|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|uniprotkb:Q92800(identity)|entrezgene/locuslink:2145(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:K4sKpUT1htSiigJaEoGyDjvkWqc9606 rogid:qp3eqBCgiaoA6VSSyqpW1d9YKN49606 intact-crc:C55F01C913B453F7|rigid:V/3af30mb9fBOZsXO1hdgP2/0Jg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5T6S3 uniprotkb:Q9BQE3 intact:EBI-2339674|uniprotkb:Q6N038|uniprotkb:Q32NF2|uniprotkb:Q8TBL6|uniprotkb:Q5T6S4|uniprotkb:Q9UFS9|ensembl:ENSP00000363003 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:phf19_human(display_long)|uniprotkb:PHF19(gene name)|psi-mi:PHF19(display_short)|uniprotkb:PCL3(gene name synonym)|uniprotkb:Polycomb-like protein 3(gene name synonym) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834756|imex:IM-21659-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011516811.1|refseq:NP_001009936.1|refseq:NP_056466.1|refseq:NP_001273769.1|refseq:NP_001273772.1|refseq:XP_005251963.1|refseq:XP_016870101.1|ensembl:ENSG00000119403(gene)|ensembl:ENST00000373896(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042017|mint:Q5T6S3|rcsb pdb:2E5Q|rcsb pdb:4BD3|rcsb pdb:6NQ3|rcsb pdb:6WAU|reactome:R-HSA-212300|uniprotkb:Q5T6S3(identity)|entrezgene/locuslink:26147(identity)|ddbj/embl/genbank:BC125076(identity) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1|uniprotkb:Q9BQE3(identity)|entrezgene/locuslink:84790(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:K4sKpUT1htSiigJaEoGyDjvkWqc9606 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:C55F01C913B453F7|rigid:V/3af30mb9fBOZsXO1hdgP2/0Jg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5T6S3 uniprotkb:Q15910 intact:EBI-2339674|uniprotkb:Q6N038|uniprotkb:Q32NF2|uniprotkb:Q8TBL6|uniprotkb:Q5T6S4|uniprotkb:Q9UFS9|ensembl:ENSP00000363003 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 psi-mi:phf19_human(display_long)|uniprotkb:PHF19(gene name)|psi-mi:PHF19(display_short)|uniprotkb:PCL3(gene name synonym)|uniprotkb:Polycomb-like protein 3(gene name synonym) psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834756|imex:IM-21659-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011516811.1|refseq:NP_001009936.1|refseq:NP_056466.1|refseq:NP_001273769.1|refseq:NP_001273772.1|refseq:XP_005251963.1|refseq:XP_016870101.1|ensembl:ENSG00000119403(gene)|ensembl:ENST00000373896(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042017|mint:Q5T6S3|rcsb pdb:2E5Q|rcsb pdb:4BD3|rcsb pdb:6NQ3|rcsb pdb:6WAU|reactome:R-HSA-212300|uniprotkb:Q5T6S3(identity)|entrezgene/locuslink:26147(identity)|ddbj/embl/genbank:BC125076(identity) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N|uniprotkb:Q15910(identity)|entrezgene/locuslink:2146(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:K4sKpUT1htSiigJaEoGyDjvkWqc9606 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 intact-crc:C55F01C913B453F7|rigid:V/3af30mb9fBOZsXO1hdgP2/0Jg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5T6S3 uniprotkb:P49411 intact:EBI-2339674|uniprotkb:Q6N038|uniprotkb:Q32NF2|uniprotkb:Q8TBL6|uniprotkb:Q5T6S4|uniprotkb:Q9UFS9|ensembl:ENSP00000363003 intact:EBI-359097|uniprotkb:O15276|ensembl:ENSP00000322439 psi-mi:phf19_human(display_long)|uniprotkb:PHF19(gene name)|psi-mi:PHF19(display_short)|uniprotkb:PCL3(gene name synonym)|uniprotkb:Polycomb-like protein 3(gene name synonym) psi-mi:eftu_human(display_long)|uniprotkb:TUFM(gene name)|psi-mi:TUFM(display_short)|uniprotkb:P43(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834756|imex:IM-21659-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011516811.1|refseq:NP_001009936.1|refseq:NP_056466.1|refseq:NP_001273769.1|refseq:NP_001273772.1|refseq:XP_005251963.1|refseq:XP_016870101.1|ensembl:ENSG00000119403(gene)|ensembl:ENST00000373896(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042017|mint:Q5T6S3|rcsb pdb:2E5Q|rcsb pdb:4BD3|rcsb pdb:6NQ3|rcsb pdb:6WAU|reactome:R-HSA-212300|uniprotkb:Q5T6S3(identity)|entrezgene/locuslink:26147(identity)|ddbj/embl/genbank:BC125076(identity) refseq:NP_003312.3|ensembl:ENSG00000178952(gene)|ensembl:ENST00000313511(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:P49411|rcsb pdb:7A5G|rcsb pdb:7O9K|reactome:R-HSA-5389840|refseq:XP_016879108.1|uniprotkb:P49411(identity)|entrezgene/locuslink:7284(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:K4sKpUT1htSiigJaEoGyDjvkWqc9606 rogid:pDRPUBUqvFqnh613N8bDTl4sFHc9606 intact-crc:C55F01C913B453F7|rigid:V/3af30mb9fBOZsXO1hdgP2/0Jg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5T6S3 uniprotkb:Q16576 intact:EBI-2339674|uniprotkb:Q6N038|uniprotkb:Q32NF2|uniprotkb:Q8TBL6|uniprotkb:Q5T6S4|uniprotkb:Q9UFS9|ensembl:ENSP00000363003 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 psi-mi:phf19_human(display_long)|uniprotkb:PHF19(gene name)|psi-mi:PHF19(display_short)|uniprotkb:PCL3(gene name synonym)|uniprotkb:Polycomb-like protein 3(gene name synonym) psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834756|imex:IM-21659-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011516811.1|refseq:NP_001009936.1|refseq:NP_056466.1|refseq:NP_001273769.1|refseq:NP_001273772.1|refseq:XP_005251963.1|refseq:XP_016870101.1|ensembl:ENSG00000119403(gene)|ensembl:ENST00000373896(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042017|mint:Q5T6S3|rcsb pdb:2E5Q|rcsb pdb:4BD3|rcsb pdb:6NQ3|rcsb pdb:6WAU|reactome:R-HSA-212300|uniprotkb:Q5T6S3(identity)|entrezgene/locuslink:26147(identity)|ddbj/embl/genbank:BC125076(identity) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|entrezgene/locuslink:5931(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:K4sKpUT1htSiigJaEoGyDjvkWqc9606 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 intact-crc:C55F01C913B453F7|rigid:V/3af30mb9fBOZsXO1hdgP2/0Jg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5T6S3 uniprotkb:Q15365 intact:EBI-2339674|uniprotkb:Q6N038|uniprotkb:Q32NF2|uniprotkb:Q8TBL6|uniprotkb:Q5T6S4|uniprotkb:Q9UFS9|ensembl:ENSP00000363003 intact:EBI-946095|uniprotkb:Q13157|uniprotkb:Q14975|ensembl:ENSP00000305556 psi-mi:phf19_human(display_long)|uniprotkb:PHF19(gene name)|psi-mi:PHF19(display_short)|uniprotkb:PCL3(gene name synonym)|uniprotkb:Polycomb-like protein 3(gene name synonym) psi-mi:pcbp1_human(display_long)|uniprotkb:PCBP1(gene name)|psi-mi:PCBP1(display_short)|uniprotkb:Alpha-CP1(gene name synonym)|uniprotkb:Nucleic acid-binding protein SUB2.3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834756|imex:IM-21659-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011516811.1|refseq:NP_001009936.1|refseq:NP_056466.1|refseq:NP_001273769.1|refseq:NP_001273772.1|refseq:XP_005251963.1|refseq:XP_016870101.1|ensembl:ENSG00000119403(gene)|ensembl:ENST00000373896(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042017|mint:Q5T6S3|rcsb pdb:2E5Q|rcsb pdb:4BD3|rcsb pdb:6NQ3|rcsb pdb:6WAU|reactome:R-HSA-212300|uniprotkb:Q5T6S3(identity)|entrezgene/locuslink:26147(identity)|ddbj/embl/genbank:BC125076(identity) refseq:NP_006187.2|dip:DIP-38136N|ensembl:ENSG00000169564(gene)|ensembl:ENST00000303577(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098847"(sequence-specific single stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15365|rcsb pdb:1WVN|rcsb pdb:1ZTG|rcsb pdb:3VKE|reactome:R-HSA-72163|reactome:R-HSA-72203|uniprotkb:Q15365(identity)|entrezgene/locuslink:5093(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:K4sKpUT1htSiigJaEoGyDjvkWqc9606 rogid:x72fawo4plQ+ipfqIoREIDHc2bA9606 intact-crc:C55F01C913B453F7|rigid:V/3af30mb9fBOZsXO1hdgP2/0Jg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5T6S3 uniprotkb:Q15022 intact:EBI-2339674|uniprotkb:Q6N038|uniprotkb:Q32NF2|uniprotkb:Q8TBL6|uniprotkb:Q5T6S4|uniprotkb:Q9UFS9|ensembl:ENSP00000363003 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 psi-mi:phf19_human(display_long)|uniprotkb:PHF19(gene name)|psi-mi:PHF19(display_short)|uniprotkb:PCL3(gene name synonym)|uniprotkb:Polycomb-like protein 3(gene name synonym) psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834756|imex:IM-21659-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011516811.1|refseq:NP_001009936.1|refseq:NP_056466.1|refseq:NP_001273769.1|refseq:NP_001273772.1|refseq:XP_005251963.1|refseq:XP_016870101.1|ensembl:ENSG00000119403(gene)|ensembl:ENST00000373896(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042017|mint:Q5T6S3|rcsb pdb:2E5Q|rcsb pdb:4BD3|rcsb pdb:6NQ3|rcsb pdb:6WAU|reactome:R-HSA-212300|uniprotkb:Q5T6S3(identity)|entrezgene/locuslink:26147(identity)|ddbj/embl/genbank:BC125076(identity) dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:Q15022(identity)|entrezgene/locuslink:23512(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:K4sKpUT1htSiigJaEoGyDjvkWqc9606 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 intact-crc:C55F01C913B453F7|rigid:V/3af30mb9fBOZsXO1hdgP2/0Jg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5T6S3 uniprotkb:O75530 intact:EBI-2339674|uniprotkb:Q6N038|uniprotkb:Q32NF2|uniprotkb:Q8TBL6|uniprotkb:Q5T6S4|uniprotkb:Q9UFS9|ensembl:ENSP00000363003 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 psi-mi:phf19_human(display_long)|uniprotkb:PHF19(gene name)|psi-mi:PHF19(display_short)|uniprotkb:PCL3(gene name synonym)|uniprotkb:Polycomb-like protein 3(gene name synonym) psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834756|imex:IM-21659-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011516811.1|refseq:NP_001009936.1|refseq:NP_056466.1|refseq:NP_001273769.1|refseq:NP_001273772.1|refseq:XP_005251963.1|refseq:XP_016870101.1|ensembl:ENSG00000119403(gene)|ensembl:ENST00000373896(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042017|mint:Q5T6S3|rcsb pdb:2E5Q|rcsb pdb:4BD3|rcsb pdb:6NQ3|rcsb pdb:6WAU|reactome:R-HSA-212300|uniprotkb:Q5T6S3(identity)|entrezgene/locuslink:26147(identity)|ddbj/embl/genbank:BC125076(identity) refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:O75530(identity)|entrezgene/locuslink:8726(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:K4sKpUT1htSiigJaEoGyDjvkWqc9606 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 intact-crc:C55F01C913B453F7|rigid:V/3af30mb9fBOZsXO1hdgP2/0Jg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5T6S3 uniprotkb:O43189 intact:EBI-2339674|uniprotkb:Q6N038|uniprotkb:Q32NF2|uniprotkb:Q8TBL6|uniprotkb:Q5T6S4|uniprotkb:Q9UFS9|ensembl:ENSP00000363003 intact:EBI-530034|uniprotkb:B1AZX2|uniprotkb:B1AZX3|uniprotkb:O60929|uniprotkb:Q96KM7|uniprotkb:Q5SU07|uniprotkb:Q5SU08|ensembl:ENSP00000363640|ensembl:ENSP00000391901|ensembl:ENSP00000407295 psi-mi:phf19_human(display_long)|uniprotkb:PHF19(gene name)|psi-mi:PHF19(display_short)|uniprotkb:PCL3(gene name synonym)|uniprotkb:Polycomb-like protein 3(gene name synonym) psi-mi:phf1_human(display_long)|uniprotkb:PCL1(gene name synonym)|uniprotkb:Polycomb-like protein 1(gene name synonym)|uniprotkb:PHF1(gene name)|psi-mi:PHF1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834756|imex:IM-21659-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011516811.1|refseq:NP_001009936.1|refseq:NP_056466.1|refseq:NP_001273769.1|refseq:NP_001273772.1|refseq:XP_005251963.1|refseq:XP_016870101.1|ensembl:ENSG00000119403(gene)|ensembl:ENST00000373896(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042017|mint:Q5T6S3|rcsb pdb:2E5Q|rcsb pdb:4BD3|rcsb pdb:6NQ3|rcsb pdb:6WAU|reactome:R-HSA-212300|uniprotkb:Q5T6S3(identity)|entrezgene/locuslink:26147(identity)|ddbj/embl/genbank:BC125076(identity) refseq:XP_011512964.1|refseq:NP_002627.1|refseq:NP_077084.1|ensembl:ENSG00000112511(gene)|ensembl:ENSG00000225553(gene)|ensembl:ENST00000374516(transcript)|ensembl:ENST00000427869(transcript)|ensembl:ENST00000454914(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR031202|interpro:IPR040477|mint:O43189|rcsb pdb:2E5P|rcsb pdb:2M0O|rcsb pdb:4HCZ|rcsb pdb:5XFN|rcsb pdb:5XFO|rcsb pdb:5XFP|rcsb pdb:6WAT|rcsb pdb:6WAV|reactome:R-HSA-212300|dip:DIP-34001N|uniprotkb:O43189(identity)|entrezgene/locuslink:5252(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:K4sKpUT1htSiigJaEoGyDjvkWqc9606 rogid:8n8g2LqzuOQb8cFC7tE1j/xBvkI9606 intact-crc:C55F01C913B453F7|rigid:V/3af30mb9fBOZsXO1hdgP2/0Jg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5T6S3 uniprotkb:A6NHQ4 intact:EBI-2339674|uniprotkb:Q6N038|uniprotkb:Q32NF2|uniprotkb:Q8TBL6|uniprotkb:Q5T6S4|uniprotkb:Q9UFS9|ensembl:ENSP00000363003 intact:EBI-8831125|ensembl:ENSP00000483859|ensembl:ENSP00000484710 psi-mi:phf19_human(display_long)|uniprotkb:PHF19(gene name)|psi-mi:PHF19(display_short)|uniprotkb:PCL3(gene name synonym)|uniprotkb:Polycomb-like protein 3(gene name synonym) psi-mi:epop_human(display_long)|uniprotkb:EPOP(gene name)|psi-mi:EPOP(display_short)|uniprotkb:C17orf96(gene name synonym)|uniprotkb:PRR28(gene name synonym)|uniprotkb:Proline-rich protein 28(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834756|imex:IM-21659-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011516811.1|refseq:NP_001009936.1|refseq:NP_056466.1|refseq:NP_001273769.1|refseq:NP_001273772.1|refseq:XP_005251963.1|refseq:XP_016870101.1|ensembl:ENSG00000119403(gene)|ensembl:ENST00000373896(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042017|mint:Q5T6S3|rcsb pdb:2E5Q|rcsb pdb:4BD3|rcsb pdb:6NQ3|rcsb pdb:6WAU|reactome:R-HSA-212300|uniprotkb:Q5T6S3(identity)|entrezgene/locuslink:26147(identity)|ddbj/embl/genbank:BC125076(identity) refseq:NP_001124149.1|ensembl:ENSG00000273604(gene)|ensembl:ENST00000613024(transcript)|ensembl:ENST00000621654(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005694"(chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0070449"(elongin complex)|interpro:IPR027971|mint:A6NHQ4|ensembl:ENSG00000277303(gene)|uniprotkb:A6NHQ4(identity)|entrezgene/locuslink:100170841(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:K4sKpUT1htSiigJaEoGyDjvkWqc9606 rogid:xxrapCjRxgY22pLac2F4zSS2bvk9606 intact-crc:C55F01C913B453F7|rigid:V/3af30mb9fBOZsXO1hdgP2/0Jg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q8IXM2 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-4280811|uniprotkb:B4DIV3|ensembl:ENSP00000411851|uniprotkb:E9PB29|uniprotkb:C9J4G0 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:bap18_human(display_long)|uniprotkb:BAP18(gene name)|psi-mi:BAP18(display_short)|uniprotkb:C17orf49(gene name synonym)|uniprotkb:BPTF-associated protein of 18 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) refseq:NP_777553.1|ensembl:ENSG00000258315(gene)|ensembl:ENST00000439424(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0016589"(NURF complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR037931|mint:Q8IXM2|refseq:NP_001136271.1|refseq:NP_001136270.1|dip:DIP-60552N|uniprotkb:Q8IXM2(identity)|entrezgene/locuslink:124944(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:JewuVFQI/LJRK5UZ0PeCsAhHGIE9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q12830 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-1560273|uniprotkb:Q6NX67|uniprotkb:Q7Z7D6|uniprotkb:Q9UIG2|ensembl:ENSP00000315454 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:bptf_human(display_long)|uniprotkb:Bromodomain and PHD finger-containing transcription factor(gene name synonym)|uniprotkb:Fetal Alzheimer antigen(gene name synonym)|uniprotkb:Fetal Alz-50 clone 1 protein(gene name synonym)|uniprotkb:BPTF(gene name)|psi-mi:BPTF(display_short)|uniprotkb:FAC1(gene name synonym)|uniprotkb:FALZ(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) refseq:NP_004450.3|refseq:NP_872579.2|dip:DIP-38919N|ensembl:ENSG00000171634(gene)|ensembl:ENST00000321892(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007492"(endoderm development)|go:"GO:0009611"(response to wounding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016589"(NURF complex)|go:"GO:0030425"(dendrite)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044297"(cell body)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018359|interpro:IPR018501|interpro:IPR019786|interpro:IPR019787|interpro:IPR028941|interpro:IPR036427|interpro:IPR038028|mint:Q12830|rcsb pdb:2F6J|rcsb pdb:2F6N|rcsb pdb:2FSA|rcsb pdb:2FUI|rcsb pdb:2FUU|rcsb pdb:2RI7|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3UV2|rcsb pdb:5H6Y|rcsb pdb:5R4G|rcsb pdb:5R4H|rcsb pdb:5R4I|rcsb pdb:5R4J|rcsb pdb:5R4K|rcsb pdb:5R4L|rcsb pdb:5R4M|rcsb pdb:5R4N|rcsb pdb:5R4O|rcsb pdb:6AZE|rcsb pdb:7K6R|rcsb pdb:7K6S|rcsb pdb:7KDW|rcsb pdb:7KDZ|uniprotkb:Q12830(identity)|entrezgene/locuslink:2186(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:QQehqJ6NUFT7JEUOto64C73imBY9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q9UBB5 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-923391|uniprotkb:Q9UIS8|uniprotkb:O95242|ensembl:ENSP00000256429 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:mbd2_human(display_long)|uniprotkb:MBD2(gene name)|psi-mi:MBD2(display_short)|uniprotkb:Methyl-CpG-binding protein MBD2(gene name synonym)|uniprotkb:Demethylase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) refseq:NP_003918.1|refseq:NP_056647.1|ensembl:ENSG00000134046(gene)|ensembl:ENST00000256429(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003696"(satellite DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034622"|go:"GO:0035197"(siRNA binding)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042711"(maternal behavior)|go:"GO:0043044"|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048568"(embryonic organ development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR025884|interpro:IPR032343|mint:Q9UBB5|rcsb pdb:2L2L|rcsb pdb:6C1A|rcsb pdb:6C1T|rcsb pdb:6C1U|rcsb pdb:6C1V|rcsb pdb:6C2F|rcsb pdb:6CNP|rcsb pdb:6CNQ|rcsb pdb:7AO8|rcsb pdb:7AO9|rcsb pdb:7AOA|reactome:R-HSA-427413|reactome:R-HSA-73728|uniprotkb:Q9UBB5(identity)|entrezgene/locuslink:8932(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:8DO+M6oIpbSfTFPVLADdXaaqzEU9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q96ST3 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-347218|uniprotkb:Q8N8N4|uniprotkb:Q8NC83|uniprotkb:Q8WV18|uniprotkb:Q96L98|uniprotkb:Q9UFQ1|intact:EBI-28985143|ensembl:ENSP00000353622|ensembl:ENSP00000378402|ensembl:ENSP00000378403|uniprotkb:B2RNS5 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:sin3a_human(display_long)|uniprotkb:SIN3A(gene name)|psi-mi:SIN3A(display_short)|uniprotkb:Transcriptional corepressor Sin3a(gene name synonym)|uniprotkb:Histone deacetylase complex subunit Sin3a(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) refseq:XP_006720528.1|ensembl:ENSG00000169375(gene)|ensembl:ENST00000360439(transcript)|ensembl:ENST00000394947(transcript)|ensembl:ENST00000394949(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007568"(aging)|go:"GO:0010817"(regulation of hormone levels)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0031937"(obsolete positive regulation of chromatin silencing)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0051595"(response to methylglyoxal)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1901675"(negative regulation of histone H3-K27 acetylation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR013194(Histone deacetylase interacting)|interpro:IPR031693|interpro:IPR036600|interpro:IPR037969|interpro:IPR039774|mint:Q96ST3|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-427413|reactome:R-HSA-8936459|reactome:R-HSA-9022538|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9022702|rcsb pdb:1PO4|reactome:R-HSA-9615017|reactome:R-HSA-9707564|reactome:R-HSA-983231|refseq:XP_006720529.1|refseq:XP_006720530.1|refseq:NP_001138829.1|refseq:NP_001138830.1|refseq:NP_056292.1|ensembl:ENSP00000353622|ensembl:ENSP00000378402|ensembl:ENSP00000378403|dip:DIP-31515N|uniprotkb:Q96ST3(identity)|entrezgene/locuslink:25942(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:pO/FziDcMNQRfy6ePi6eNKELXVM9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q96GY3 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-748884|uniprotkb:O14557|uniprotkb:Q7Z2T9|uniprotkb:A8KAQ1|ensembl:ENSP00000301159 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:lin37_human(display_long)|uniprotkb:Antolefinin(gene name synonym)|uniprotkb:LIN37(gene name)|psi-mi:LIN37(display_short)|uniprotkb:MSTP064(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) refseq:NP_061977.1|ensembl:ENSG00000267796(gene)|ensembl:ENST00000301159(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005654"(nucleoplasm)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0031523"(Myb complex)|interpro:IPR028226|mint:Q96GY3|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|uniprotkb:Q96GY3(identity)|entrezgene/locuslink:55957(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:3AlABMJE4m84S7ZZeYB3tyJbbqw9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q9Y483 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-725816|uniprotkb:A6NGQ9|uniprotkb:Q9UES9|uniprotkb:Q9UP40|uniprotkb:A8K2Q3|uniprotkb:B1AKT5|intact:EBI-11028207|uniprotkb:Q96G26|uniprotkb:B1AKT6|ensembl:ENSP00000359321 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:mtf2_human(display_long)|uniprotkb:PCL2(gene name synonym)|uniprotkb:Metal-response element DNA-binding protein M96(gene name synonym)|uniprotkb:Metal regulatory transcription factor 2(gene name synonym)|uniprotkb:Polycomb-like protein 2(gene name synonym)|uniprotkb:MTF2(gene name)|psi-mi:MTF2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) refseq:NP_001157863.1|refseq:NP_001157865.1|refseq:NP_031384.1|refseq:XP_011539318.1|refseq:XP_016856165.1|ensembl:ENSG00000143033(gene)|ensembl:ENST00000370298(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042015|mint:Q9Y483|rcsb pdb:5XFR|reactome:R-HSA-212300|interpro:IPR042014|refseq:NP_001157864.1|uniprotkb:Q9Y483(identity)|entrezgene/locuslink:22823(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:Im8E6U/OPb8AEir43AUUDlU6F2o9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q12873 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-523590|uniprotkb:Q9Y4I0|intact:EBI-28978117|ensembl:ENSP00000332628|uniprotkb:D3DTQ9|uniprotkb:E9PG89 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:chd3_human(display_long)|uniprotkb:ATP-dependent helicase CHD3(gene name synonym)|uniprotkb:Mi-2 autoantigen 240 kDa protein(gene name synonym)|uniprotkb:Mi2-alpha(gene name synonym)|uniprotkb:Zinc finger helicase(gene name synonym)|uniprotkb:CHD3(gene name)|psi-mi:CHD3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) interpro:IPR023780|interpro:IPR027417|interpro:IPR036910|interpro:IPR038718|mint:Q12873|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-4551638|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|ensembl:ENSG00000170004(gene)|ensembl:ENST00000330494(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007051"(spindle organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0016605"(PML body)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036121"(double-stranded DNA helicase activity)|go:"GO:0043044"|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|go:"GO:0070615"|interpro:IPR019787|interpro:IPR023779|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|ensembl:ENSP00000332628|ensembl:ENST00000358181|ensembl:ENSP00000350907|ensembl:ENST00000380358|ensembl:ENSP00000369716|refseq:NP_001005271.2|refseq:NP_001005273.1|refseq:NP_005843.2|dip:DIP-32496N|uniprotkb:Q12873(identity)|entrezgene/locuslink:1107(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:UjefFUXiV28qhOP9BoIUansxl+k9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:O60684 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-359923|uniprotkb:Q5VVU3|uniprotkb:B2RDC7|ensembl:ENSP00000362728|uniprotkb:D3DPP5 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:ima7_human(display_long)|uniprotkb:KPNA6(gene name)|psi-mi:KPNA6(display_short)|uniprotkb:IPOA7(gene name synonym)|uniprotkb:Karyopherin subunit alpha-6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) refseq:NP_036448.1|ensembl:ENSG00000025800(gene)|ensembl:ENST00000373625(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0019079"(viral genome replication)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0043657"(host cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O60684|rcsb pdb:4UAD|dip:DIP-27609N|uniprotkb:O60684(identity)|entrezgene/locuslink:23633(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:3NsSIcE6BHIqYlvfGRolUKD/5uc9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q9BQE3 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1|uniprotkb:Q9BQE3(identity)|entrezgene/locuslink:84790(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q16576 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|entrezgene/locuslink:5931(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q9NP50 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-741906|ensembl:ENSP00000337477|ensembl:ENSP00000393279|ensembl:ENSP00000479093|ensembl:ENSP00000488570|uniprotkb:Q9BSZ8|uniprotkb:D3DUV8 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:shcaf_human(display_long)|uniprotkb:SINHCAF(gene name)|psi-mi:SINHCAF(display_short)|uniprotkb:C12orf14(gene name synonym)|uniprotkb:FAM60A(gene name synonym)|uniprotkb:Protein FAM60A(gene name synonym)|uniprotkb:Tera protein homolog(gene name synonym)|uniprotkb:L4(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) ensembl:ENSG00000139146(gene)|ensembl:ENSG00000276371(gene)|ensembl:ENST00000337682(transcript)|ensembl:ENST00000454658(transcript)|ensembl:ENST00000617411(transcript)|ensembl:ENST00000633702(transcript)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0045596"(negative regulation of cell differentiation)|interpro:IPR026065|mint:Q9NP50|refseq:NP_001129283.1|refseq:NP_001129284.1|refseq:NP_067061.1|refseq:XP_016875247.1|refseq:XP_016875248.1|refseq:XP_016875249.1|refseq:XP_016875250.1|refseq:XP_016875251.1|uniprotkb:Q9NP50(identity)|entrezgene/locuslink:58516(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:LVESO8KQhobNYQduBQ/iAmNaNTM9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q8N7W2 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-743382|uniprotkb:Q5SYY7|uniprotkb:Q5SYY8|uniprotkb:Q5SYY9|uniprotkb:Q8N5T7 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:bend7_human(display_long)|uniprotkb:BEND7(gene name)|psi-mi:BEND7(display_short)|uniprotkb:C10orf30(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) go:"GO:0070062"(extracellular exosome)|refseq:NP_001094382.1|refseq:NP_689964.2|interpro:IPR018379|refseq:XP_011517694.1|refseq:XP_011517713.1|mint:Q8N7W2|uniprotkb:Q8N7W2(identity)|entrezgene/locuslink:222389(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:mI/DE8ufhQLhjvmytV1m4g24Yqk9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q6MZP7 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-1389411|uniprotkb:Q32M68|uniprotkb:Q32M69|uniprotkb:Q6N071|uniprotkb:Q76B60|ensembl:ENSP00000341947|ensembl:ENSP00000425844 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:lin54_human(display_long)|uniprotkb:CXCDC1(gene name synonym)|uniprotkb:KIAA2037(gene name synonym)|uniprotkb:CXC domain-containing protein 1(gene name synonym)|uniprotkb:LIN54(gene name)|psi-mi:LIN54(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) refseq:XP_006714144.1|refseq:NP_001108479.1|refseq:NP_001108480.1|refseq:NP_919258.2|refseq:XP_016863217.1|refseq:XP_016863218.1|refseq:XP_016863219.1|refseq:XP_005262807.1|refseq:NP_001275925.1|refseq:NP_001275926.1|ensembl:ENSG00000189308(gene)|ensembl:ENST00000340417(transcript)|ensembl:ENST00000505397(transcript)|go:"GO:0001067"(transcription regulatory region nucleic acid binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0046872"(metal ion binding)|interpro:IPR005172(Tesmin/TSO1-like, CXC)|interpro:IPR028307|interpro:IPR033467|mint:Q6MZP7|rcsb pdb:5FD3|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|uniprotkb:Q6MZP7(identity)|entrezgene/locuslink:132660(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:RZwf5ctBfCw6s64KOOe8DkUmM609606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:P10244 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-1389468|uniprotkb:B2RBS5|uniprotkb:B7Z8D9|uniprotkb:F8W6N6|uniprotkb:Q53F07|ensembl:ENSP00000217026 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:mybb_human(display_long)|uniprotkb:Myb-like protein 2(gene name synonym)|uniprotkb:MYBL2(gene name)|psi-mi:MYBL2(display_short)|uniprotkb:BMYB(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) refseq:NP_001265539.1|refseq:NP_002457.1|ensembl:ENSG00000101057(gene)|ensembl:ENST00000217026(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0031523"(Myb complex)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015395(C-myb, C-terminal)|interpro:IPR017930|interpro:IPR028311|mint:P10244|rcsb pdb:6C48|reactome:R-HSA-1362300|reactome:R-HSA-156711|reactome:R-HSA-8869496|uniprotkb:P10244(identity)|entrezgene/locuslink:4605(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:2ldntN2B+u1fHcK4WPkL9UZYbzs9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q9C005 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-744973|uniprotkb:D6W578|ensembl:ENSP00000295066|ensembl:ENSP00000345837 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:dpy30_human(display_long)|uniprotkb:DPY30(gene name)|psi-mi:DPY30(display_short)|uniprotkb:Dpy-30-like protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) refseq:NP_115963.1|ensembl:ENSG00000162961(gene)|ensembl:ENST00000295066(transcript)|ensembl:ENST00000342166(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006348"|go:"GO:0016197"(endosomal transport)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|mint:Q9C005|rcsb pdb:3G36|rcsb pdb:4RIQ|rcsb pdb:4RT4|rcsb pdb:4RTA|rcsb pdb:6E2H|rcsb pdb:6PWV|reactome:R-HSA-3214841|reactome:R-HSA-8936459|refseq:NP_001308138.1|dip:DIP-34476N|uniprotkb:Q9C005(identity)|entrezgene/locuslink:84661(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:yC9NJhTfEIT+YyfWRSJLGbRsQkc9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q9BTC8 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-2461787|uniprotkb:Q9NSP2|uniprotkb:Q9ULF4|ensembl:ENSP00000385823 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:mta3_human(display_long)|uniprotkb:MTA3(gene name)|psi-mi:MTA3(display_short)|uniprotkb:KIAA1266(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) refseq:NP_001269684.1|refseq:NP_001269685.1|refseq:NP_065795.1|refseq:NP_001317371.1|dip:DIP-47460N|ensembl:ENST00000405094(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR035170|interpro:IPR040138|interpro:IPR043151|mint:Q9BTC8|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|ensembl:ENSG00000057935(gene)|uniprotkb:Q9BTC8(identity)|entrezgene/locuslink:57504(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:wxPsfH6FguY8n4PFwaj1iJNTWPc9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:O75182 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-540462|uniprotkb:Q68GC2|uniprotkb:Q6P4B8|uniprotkb:Q8TB34|uniprotkb:Q9BSC8|uniprotkb:Q2NL91|ensembl:ENSP00000369131 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:sin3b_human(display_long)|uniprotkb:Transcriptional corepressor Sin3b(gene name synonym)|uniprotkb:Histone deacetylase complex subunit Sin3b(gene name synonym)|uniprotkb:SIN3B(gene name)|psi-mi:SIN3B(display_short)|uniprotkb:KIAA0700(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) refseq:NP_056075.1|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0030849"(autosome)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR013194(Histone deacetylase interacting)|interpro:IPR031693|go:"GO:0003682"(chromatin binding)|interpro:IPR036600|interpro:IPR039774|mint:O75182|reactome:R-HSA-400206|reactome:R-HSA-427413|reactome:R-HSA-8936459|reactome:R-HSA-9707564|ensembl:ENSG00000127511(gene)|ensembl:ENST00000379803(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000805"(X chromosome)|go:"GO:0000806"(Y chromosome)|go:"GO:0001741"(XY body)|refseq:NP_001284524.1|refseq:NP_001284526.1|uniprotkb:O75182(identity)|entrezgene/locuslink:23309(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:ney2nq8TMh2sFxskgXr+NgNCl349606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:P45973 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|entrezgene/locuslink:23468(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q5TKA1 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-1389424|uniprotkb:Q5U5L8|uniprotkb:Q5U7E1|uniprotkb:Q6PI55|uniprotkb:Q6ZTV4|uniprotkb:Q7Z3J1|ensembl:ENSP00000505590 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:lin9_human(display_long)|uniprotkb:Beta subunit-associated regulator of apoptosis(gene name synonym)|uniprotkb:Type I interferon receptor beta chain-associated protein(gene name synonym)|uniprotkb:TUDOR gene similar protein(gene name synonym)|uniprotkb:pRB-associated protein(gene name synonym)|uniprotkb:LIN9(gene name)|psi-mi:LIN9(display_short)|uniprotkb:BARA(gene name synonym)|uniprotkb:TGS(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) refseq:NP_775106.2|refseq:NP_001257338.1|refseq:NP_001257339.1|ensembl:ENSG00000183814(gene)|ensembl:ENST00000681046(transcript)|go:"GO:0000003"(reproduction)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071897"(DNA biosynthetic process)|interpro:IPR010561(DIRP)|interpro:IPR033471|mint:Q5TKA1|rcsb pdb:6C48|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|go:"GO:0017053"(transcription repressor complex)|uniprotkb:Q5TKA1(identity)|entrezgene/locuslink:286826(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:ATFX38+7N6NzEysrzMmHvn22jaA9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q6ZN18 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-743256|ensembl:ENSP00000381840|uniprotkb:Q59FS5|uniprotkb:Q6ZN62|uniprotkb:Q96BG3 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:aebp2_human(display_long)|uniprotkb:Adipocyte enhancer-binding protein 2(gene name synonym)|uniprotkb:AEBP2(gene name)|psi-mi:AEBP2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) ensembl:ENSG00000139154(gene)|interpro:IPR036236|ensembl:ENST00000398864(transcript)|go:"GO:0000785"(chromatin)|mint:Q6ZN18|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001107648.1|refseq:NP_694939.2|rcsb pdb:5WAI|rcsb pdb:5Y0U|rcsb pdb:5Y1U|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|reactome:R-HSA-3214841|refseq:NP_001253972.1|dip:DIP-58581N|uniprotkb:Q6ZN18(identity)|entrezgene/locuslink:121536(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:mOY+NOTaqJlXjW8v6D3YPnfnfBU9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q8WXI9 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-923440|uniprotkb:Q5VUR2|uniprotkb:Q7LG68|uniprotkb:Q9ULS0|uniprotkb:D3DUZ2|ensembl:ENSP00000357644|ensembl:ENSP00000458280|ensembl:ENSP00000489184 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:p66b_human(display_long)|uniprotkb:GATAD2B(gene name)|psi-mi:GATAD2B(display_short)|uniprotkb:KIAA1150(gene name synonym)|uniprotkb:p66/p68(gene name synonym)|uniprotkb:GATA zinc finger domain-containing protein 2B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) refseq:NP_065750.1|refseq:XP_005245421.1|dip:DIP-36054N|ensembl:ENSG00000143614(gene)|ensembl:ENSG00000261992(gene)|ensembl:ENST00000368655(transcript)|ensembl:ENST00000576342(transcript)|ensembl:ENST00000634544(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR032346|interpro:IPR040386|mint:Q8WXI9|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|uniprotkb:Q8WXI9(identity)|entrezgene/locuslink:57459(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:pLKkMcJBBWdyMTf+2axWzvZLKP09606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q9Y294 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-749553|uniprotkb:Q6IA08|uniprotkb:Q9P014|ensembl:ENSP00000229595 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:asf1a_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog A(gene name synonym)|uniprotkb:CCG1-interacting factor A(gene name synonym)|uniprotkb:ASF1A(gene name)|psi-mi:ASF1A(display_short)|uniprotkb:CGI-98(orf name)|uniprotkb:HSPC146(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) refseq:NP_054753.1|dip:DIP-29241N|ensembl:ENSG00000111875(gene)|ensembl:ENST00000229595(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042692"(muscle cell differentiation)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9Y294|rcsb pdb:1TEY|rcsb pdb:2I32|rcsb pdb:2IIJ|rcsb pdb:2IO5|rcsb pdb:3AAD|rcsb pdb:5C3I|rcsb pdb:6F0G|rcsb pdb:6F0H|rcsb pdb:6ZUF|reactome:R-HSA-2559584|rcsb pdb:6F0F|uniprotkb:Q9Y294(identity)|entrezgene/locuslink:25842(identity) psi-mi:"MI:0469"(intact) - caution:This sequence has been withdrawn from Uniprot. figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:rIMptRSOYD+wfp0dMEHjhNNsHXQ9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q92769 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-301821|uniprotkb:Q5SRI8|uniprotkb:Q5SZ86|uniprotkb:Q8NEH4|uniprotkb:B4DL58|ensembl:ENSP00000430432|uniprotkb:E1P561|uniprotkb:B3KRS5 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:hdac2_human(display_long)|uniprotkb:HDAC2(gene name)|psi-mi:HDAC2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035094"(response to nicotine)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042220"(response to cocaine)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q92769|rcsb pdb:3MAX|rcsb pdb:4LXZ|rcsb pdb:4LY1|rcsb pdb:5IWG|rcsb pdb:5IX0|rcsb pdb:6G3O|rcsb pdb:6WBW|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000196591(gene)|ensembl:ENST00000519065(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|rcsb pdb:6WHN|rcsb pdb:6WHO|rcsb pdb:6WHQ|rcsb pdb:6WHZ|rcsb pdb:6WI3|rcsb pdb:6XDM|rcsb pdb:6XEB|rcsb pdb:6XEC|rcsb pdb:7KBG|rcsb pdb:7KBH|rcsb pdb:7LTG|rcsb pdb:7LTK|rcsb pdb:7LTL|reactome:R-HSA-193670|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9615017|reactome:R-HSA-9619665|reactome:R-HSA-9679191|reactome:R-HSA-983231|rcsb pdb:6WBZ|refseq:NP_001518.3|dip:DIP-24220N|refseq:XP_011534090.1|refseq:XP_016866288.1|uniprotkb:Q92769(identity)|entrezgene/locuslink:3066(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:K4PpGz9E9/TrQZsgvrJuc+uYCn89606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q13111 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-1020839|uniprotkb:Q7Z7K3|uniprotkb:Q9UJY8|uniprotkb:Q6NXG5|intact:EBI-28985893|ensembl:ENSP00000301280 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:caf1a_human(display_long)|uniprotkb:CHAF1A(gene name)|psi-mi:CHAF1A(display_short)|uniprotkb:CAF(gene name synonym)|uniprotkb:CAF1P150(gene name synonym)|uniprotkb:Chromatin assembly factor I p150 subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) refseq:NP_005474.2|ensembl:ENSG00000167670(gene)|ensembl:ENST00000301280(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070087"(chromo shadow domain binding)|interpro:IPR022043|interpro:IPR029091|interpro:IPR029105|mint:Q13111|ensembl:ENSP00000301280|dip:DIP-31135N|uniprotkb:Q13111(identity)|entrezgene/locuslink:10036(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:8ZlQPVvmtN638aK8ZblErN5Bhjo9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q5T6S3 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-2339674|uniprotkb:Q6N038|uniprotkb:Q32NF2|uniprotkb:Q8TBL6|uniprotkb:Q5T6S4|uniprotkb:Q9UFS9|ensembl:ENSP00000363003 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:phf19_human(display_long)|uniprotkb:PHF19(gene name)|psi-mi:PHF19(display_short)|uniprotkb:PCL3(gene name synonym)|uniprotkb:Polycomb-like protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) refseq:XP_011516811.1|refseq:NP_001009936.1|refseq:NP_056466.1|refseq:NP_001273769.1|refseq:NP_001273772.1|refseq:XP_005251963.1|refseq:XP_016870101.1|ensembl:ENSG00000119403(gene)|ensembl:ENST00000373896(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042017|mint:Q5T6S3|rcsb pdb:2E5Q|rcsb pdb:4BD3|rcsb pdb:6NQ3|rcsb pdb:6WAU|reactome:R-HSA-212300|uniprotkb:Q5T6S3(identity)|entrezgene/locuslink:26147(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:K4sKpUT1htSiigJaEoGyDjvkWqc9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q14839 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-372916|uniprotkb:Q8IXZ5|intact:EBI-28978241|ensembl:ENSP00000440542 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:chd4_human(display_long)|uniprotkb:CHD4(gene name)|psi-mi:CHD4(display_short)|uniprotkb:ATP-dependent helicase CHD4(gene name synonym)|uniprotkb:Mi-2 autoantigen 218 kDa protein(gene name synonym)|uniprotkb:Mi2-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) ensembl:ENSP00000440542|ensembl:ENST00000645095|ensembl:ENSP00000496634|refseq:NP_001264.2|refseq:XP_006719021.1|refseq:NP_001284482.1|ensembl:ENSG00000111642(gene)|ensembl:ENST00000544040(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070615"|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q14839|rcsb pdb:1MM2|rcsb pdb:1MM3|rcsb pdb:2EE1|rcsb pdb:2L5U|rcsb pdb:2L75|rcsb pdb:2N5N|rcsb pdb:4O9I|rcsb pdb:6BGG|rcsb pdb:6Q3M|rcsb pdb:6RYR|rcsb pdb:6RYU|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9031628|reactome:R-HSA-9679191|dip:DIP-31183N|uniprotkb:Q14839(identity)|entrezgene/locuslink:1108(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:E9eHT/41SIFRiz54J81hvPQeHIE9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:O75530 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:O75530(identity)|entrezgene/locuslink:8726(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q8NCD3 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-719429|intact:EBI-2561961|uniprotkb:A8IRH5|uniprotkb:Q9BUT2|uniprotkb:Q9NSL8|uniprotkb:B4DWR0|uniprotkb:B4DZV4|intact:EBI-28976688|ensembl:ENSP00000414109 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:hjurp_human(display_long)|uniprotkb:FAKTS(gene name synonym)|uniprotkb:URLC9(gene name synonym)|uniprotkb:14-3-3-associated AKT substrate(gene name synonym)|uniprotkb:Fetal liver-expressing gene 1 protein(gene name synonym)|uniprotkb:Up-regulated in lung cancer 9(gene name synonym)|uniprotkb:HJURP(gene name)|psi-mi:HJURP(display_short)|uniprotkb:FLEG1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) refseq:NP_001269891.1|refseq:NP_001269892.1|refseq:NP_060880.3|ensembl:ENSP00000414109|ensembl:ENST00000432087|ensembl:ENSP00000407208|ensembl:ENST00000441687|ensembl:ENSP00000401944|ensembl:ENSG00000123485(gene)|ensembl:ENST00000411486(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034080"(CENP-A containing chromatin assembly)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0051101"(regulation of DNA binding)|interpro:IPR018465|interpro:IPR021052|interpro:IPR022102|mint:Q8NCD3|rcsb pdb:3R45|reactome:R-HSA-606279|dip:DIP-53282N|uniprotkb:Q8NCD3(identity)|entrezgene/locuslink:55355(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:pUujTbXXH/IPt8rusd4Nef0rfrk9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q52LA3 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-1389456|ensembl:ENSP00000501511 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:lin52_human(display_long)|uniprotkb:LIN52(gene name)|psi-mi:LIN52(display_short)|uniprotkb:C14orf46(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) refseq:NP_001019845.1|ensembl:ENST00000674221(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0070176"(DRM complex)|interpro:IPR018737|mint:Q52LA3|rcsb pdb:4YOO|rcsb pdb:6C48|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|ensembl:ENSG00000205659(gene)|uniprotkb:Q52LA3(identity)|entrezgene/locuslink:91750(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:PYctE1wLvOx8wZn+fJU8nDk1v0w9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q9H165 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-765567|uniprotkb:Q86W14|uniprotkb:Q8WU92|uniprotkb:Q96JL6|uniprotkb:Q9H163|uniprotkb:Q9H164|uniprotkb:Q9H3G9|uniprotkb:Q9NWA7|uniprotkb:D6W5D7|uniprotkb:Q66LN6|ensembl:ENSP00000496168 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:bc11a_human(display_long)|uniprotkb:B-cell CLL/lymphoma 11A(gene name synonym)|uniprotkb:COUP-TF-interacting protein 1(gene name synonym)|uniprotkb:Ecotropic viral integration site 9 protein homolog(gene name synonym)|uniprotkb:BCL11A(gene name)|psi-mi:BCL11A(display_short)|uniprotkb:CTIP1(gene name synonym)|uniprotkb:EVI9(gene name synonym)|uniprotkb:KIAA1809(gene name synonym)|uniprotkb:ZNF856(gene name synonym)|uniprotkb:Zinc finger protein 856(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) refseq:NP_060484.2|refseq:NP_075044.2|refseq:NP_612569.1|refseq:XP_011531211.1|refseq:XP_016859823.1|dip:DIP-45629N|ensembl:ENSG00000119866(gene)|ensembl:ENST00000642384(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001067"(transcription regulatory region nucleic acid binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0032463"(negative regulation of protein homooligomerization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048672"(positive regulation of collateral sprouting)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:1903860"(negative regulation of dendrite extension)|go:"GO:1904800"(negative regulation of neuron remodeling)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9H165|rcsb pdb:5VTB|rcsb pdb:6KI6|rcsb pdb:6U9Q|go:"GO:2000173"(negative regulation of branching morphogenesis of a nerve)|uniprotkb:Q9H165(identity)|entrezgene/locuslink:53335(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:xASsLQWykg/7ZpyjLsQP8GlQ/H09606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q9HAJ7 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-2340040|uniprotkb:E9PAU7|uniprotkb:E9PAY2|ensembl:ENSP00000297109 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:sp30l_human(display_long)|uniprotkb:SAP30L(gene name)|psi-mi:SAP30L(display_short)|uniprotkb:NS4ATP2(gene name synonym)|uniprotkb:Sin3-associated protein p30-like(gene name synonym)|uniprotkb:Sin3 corepressor complex subunit SAP30L(gene name synonym)|uniprotkb:HCV non-structural protein 4A-transactivated protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) refseq:NP_001124534.1|refseq:NP_001124535.1|refseq:NP_078908.1|ensembl:ENSG00000164576(gene)|ensembl:ENST00000297109(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0042393"(histone binding)|go:"GO:0044378"(non-sequence-specific DNA binding, bending)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|interpro:IPR024145|interpro:IPR025717|interpro:IPR025718|interpro:IPR038291|rcsb pdb:2N1U|reactome:R-HSA-3214815|reactome:R-HSA-427413|reactome:R-HSA-9679191|uniprotkb:Q9HAJ7(identity)|entrezgene/locuslink:79685(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:P+sxdU4GuYQwPnJPJSsBUwF6VnY9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q96NW4 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-6125599|uniprotkb:Q71MF5|uniprotkb:Q86UC3|uniprotkb:Q8ND80|uniprotkb:Q9H0I4|ensembl:ENSP00000304292 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:anr27_human(display_long)|uniprotkb:ANKRD27(gene name)|psi-mi:ANKRD27(display_short)|uniprotkb:VPS9 domain-containing protein(gene name synonym)|uniprotkb:PP12899(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) refseq:NP_115515.2|refseq:XP_006723475.1|dip:DIP-57614N|ensembl:ENSG00000105186(gene)|ensembl:ENST00000306065(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0035544"(negative regulation of SNARE complex assembly)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0042470"(melanosome)|go:"GO:0043005"(neuron projection)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0097422"(tubular endosome)|interpro:IPR002110(Ankyrin)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR020683|interpro:IPR036770|interpro:IPR037191|mint:Q96NW4|rcsb pdb:4B93|rcsb pdb:4CYM|rcsb pdb:4CZ2|rcsb pdb:6TL0|reactome:R-HSA-8876198|uniprotkb:Q96NW4(identity)|entrezgene/locuslink:84079(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:1hfY0RGhjr0U+gpqsM9HLYLs3Ks9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q96N64 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-6597774|uniprotkb:Q2HJJ2|uniprotkb:Q8IYR3|uniprotkb:Q96PV3|uniprotkb:G5EA07|ensembl:ENSP00000305151 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:pwp2a_human(display_long)|uniprotkb:PWWP2A(gene name)|psi-mi:PWWP2A(display_short)|uniprotkb:KIAA1935(gene name synonym)|uniprotkb:MST101(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) refseq:NP_001124336.1|refseq:NP_443159.1|refseq:NP_001253964.1|ensembl:ENSG00000170234(gene)|ensembl:ENST00000307063(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0042393"(histone binding)|interpro:IPR000313(PWWP)|mint:Q96N64|uniprotkb:Q96N64(identity)|entrezgene/locuslink:114825(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:dRVLcq751e3y+moSaAoqbKU++HQ9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q13547 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-301834|uniprotkb:Q92534|ensembl:ENSP00000362649 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:hdac1_human(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:RPD3L1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) ensembl:ENSG00000116478(gene)|ensembl:ENST00000373548(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007492"(endoderm development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031000"(response to caffeine)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043044"|go:"GO:0019213"(deacetylase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900221"(regulation of amyloid-beta clearance)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q13547|rcsb pdb:1TYI|rcsb pdb:4BKX|rcsb pdb:5ICN|rcsb pdb:6Z2J|rcsb pdb:6Z2K|rcsb pdb:7AO8|rcsb pdb:7AO9|rcsb pdb:7AOA|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-193670|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-3769402|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-4641265|reactome:R-HSA-6804758|reactome:R-HSA-69205|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9022538|reactome:R-HSA-9022692|go:"GO:0017053"(transcription repressor complex)|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9615017|reactome:R-HSA-9679191|reactome:R-HSA-983231|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:NP_004955.2|dip:DIP-24184N|uniprotkb:Q13547(identity)|entrezgene/locuslink:3065(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:RP+yIBWH55NgoPTY1nKXqeJL/xY9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q8WUU4 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-8834821|ensembl:ENSP00000302770 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:zn296_human(display_long)|uniprotkb:ZNF342(gene name synonym)|uniprotkb:Zinc finger protein 342(gene name synonym)|uniprotkb:ZNF296(gene name)|psi-mi:ZNF296(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) refseq:NP_660331.1|ensembl:ENSG00000170684(gene)|ensembl:ENST00000303809(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|uniprotkb:Q8WUU4(identity)|entrezgene/locuslink:162979(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:vjlS3Ns4JBJHA8afh2dI6dd+Nsk9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:O94776 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-1783035|uniprotkb:Q68DB1|uniprotkb:Q9UQB5|ensembl:ENSP00000278823 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:mta2_human(display_long)|uniprotkb:MTA2(gene name)|psi-mi:MTA2(display_short)|uniprotkb:MTA1L1(gene name synonym)|uniprotkb:PID(gene name synonym)|uniprotkb:Metastasis-associated 1-like 1(gene name synonym)|uniprotkb:p53 target protein in deacetylase complex(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) refseq:NP_004730.2|refseq:NP_001317221.1|dip:DIP-46519N|ensembl:ENSG00000149480(gene)|ensembl:ENST00000278823(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006306"(DNA methylation)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0016020"(membrane)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR035170|interpro:IPR037964|interpro:IPR040138|interpro:IPR043151|mint:O94776|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|uniprotkb:O94776(identity)|entrezgene/locuslink:9219(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:D4wOsdMJYhY/ltvcnnuMHqNrFkc9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q5SY16 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-1055462|uniprotkb:Q4VBY3|uniprotkb:Q6P472|uniprotkb:Q7L4D6|uniprotkb:Q96EE0|uniprotkb:Q9H5L4|uniprotkb:Q2NL84|ensembl:ENSP00000366934 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:nol9_human(display_long)|uniprotkb:NOL9(gene name)|psi-mi:NOL9(display_short)|uniprotkb:Nucleolar protein 9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) refseq:NP_078930.3|refseq:XP_011540449.1|ensembl:ENST00000377705(transcript)|go:"GO:0000448"("cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051731"(polynucleotide 5'-hydroxyl-kinase activity)|interpro:IPR027417|interpro:IPR032319|mint:Q5SY16|reactome:R-HSA-6791226|ensembl:ENSG00000162408(gene)|refseq:XP_016857827.1|refseq:XP_016857828.1|uniprotkb:Q5SY16(identity)|entrezgene/locuslink:79707(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:IWGhuh/G+MlTxlSXEcIml8tvK7Y9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:O14519 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-1052532|uniprotkb:F5GYA4|intact:EBI-10988349|ensembl:ENSP00000261692 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:cdka1_human(display_long)|uniprotkb:Putative oral cancer suppressor(gene name synonym)|uniprotkb:Deleted in oral cancer 1(gene name synonym)|uniprotkb:CDK2AP1(gene name)|psi-mi:CDK2AP1(display_short)|uniprotkb:CDKAP1(gene name synonym)|uniprotkb:DOC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) refseq:NP_004633.1|refseq:NP_001257362.1|refseq:NP_001257363.1|ensembl:ENSG00000111328(gene)|ensembl:ENST00000261692(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0007049"(cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070182"(DNA polymerase binding)|interpro:IPR017266(Cyclin-dependent kinase 2-associated protein 2)|mint:O14519|rcsb pdb:2KW6|uniprotkb:O14519(identity)|entrezgene/locuslink:8099(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:ZFfQSqkET3VpjG8UrdHokYRGzj09606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q15022 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:Q15022(identity)|entrezgene/locuslink:23512(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:O95983 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-1783068|uniprotkb:Q6PIL9|uniprotkb:Q6PJZ9|uniprotkb:Q86XF4|uniprotkb:A8K4B7|uniprotkb:D6W5Z2|ensembl:ENSP00000412302 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:mbd3_human(display_long)|uniprotkb:MBD3(gene name)|psi-mi:MBD3(display_short)|uniprotkb:Methyl-CpG-binding protein MBD3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) refseq:NP_001268382.1|refseq:NP_001268383.1|dip:DIP-46517N|ensembl:ENSG00000071655(gene)|ensembl:ENST00000434436(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0009888"(tissue development)|go:"GO:0016573"(histone acetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0048568"(embryonic organ development)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR025884|interpro:IPR032343|interpro:IPR037965|mint:O95983|rcsb pdb:2MB7|rcsb pdb:6CC8|rcsb pdb:6CCG|rcsb pdb:6CEU|rcsb pdb:6CEV|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|uniprotkb:O95983(identity)|entrezgene/locuslink:53615(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:lm8jh0YVLdljXDhjkTm9B1YSsWA9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q9NVP2 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-1055650|uniprotkb:Q53G51|uniprotkb:Q9NVZ0|ensembl:ENSP00000263382|ensembl:ENSP00000499863 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:asf1b_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog B(gene name synonym)|uniprotkb:CCG1-interacting factor A-II(gene name synonym)|uniprotkb:ASF1B(gene name)|psi-mi:ASF1B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) refseq:NP_060624.1|ensembl:ENSG00000105011(gene)|ensembl:ENSG00000288210(gene)|ensembl:ENST00000263382(transcript)|ensembl:ENST00000672225(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9NVP2|rcsb pdb:5BNX|rcsb pdb:5BO0|dip:DIP-29242N|uniprotkb:Q9NVP2(identity)|entrezgene/locuslink:55723(identity) psi-mi:"MI:0469"(intact) - caution:This sequence has been withdrawn from Uniprot. figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:gG2Px6QOw95EohRaaWivH7GrSr09606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q96KM6 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-1049952|uniprotkb:Q08AK9|uniprotkb:Q9ULM4|ensembl:ENSP00000358904 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:z512b_human(display_long)|uniprotkb:ZNF512B(gene name)|psi-mi:ZNF512B(display_short)|uniprotkb:KIAA1196(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) refseq:NP_065764.1|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q96KM6|rcsb pdb:2GQJ|reactome:R-HSA-9013424|go:"GO:0046872"(metal ion binding)|ensembl:ENSG00000196700(gene)|ensembl:ENST00000369888(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|refseq:XP_011527231.1|uniprotkb:Q96KM6(identity)|entrezgene/locuslink:57473(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:kdtiH1kX3fw2Si0UVegJb6AS+709606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q15910 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N|uniprotkb:Q15910(identity)|entrezgene/locuslink:2146(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q13330 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-714236|uniprotkb:Q8NFI8|uniprotkb:Q96GI8|uniprotkb:A5PLK4|intact:EBI-28976623|ensembl:ENSP00000333633|uniprotkb:Q86SW2 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:mta1_human(display_long)|uniprotkb:MTA1(gene name)|psi-mi:MTA1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) refseq:NP_001190187.1|refseq:NP_004680.2|ensembl:ENSP00000333633|ensembl:ENST00000405646|ensembl:ENSP00000384180|ensembl:ENST00000438610|ensembl:ENSP00000393438|ensembl:ENSG00000182979(gene)|ensembl:ENST00000331320(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|reactome:R-HSA-427389|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|reactome:R-HSA-3232118|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR035170|interpro:IPR040138|mint:Q13330|rcsb pdb:4BKX|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:5FXY|rcsb pdb:5ICN|rcsb pdb:6G16|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AO8|go:"GO:0045475"(locomotor rhythm)|rcsb pdb:7AO9|rcsb pdb:7AOA|reactome:R-HSA-3214815|dip:DIP-41751N|uniprotkb:Q13330(identity)|entrezgene/locuslink:9112(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:nDDSb5B6YCbq5/6qvgtnUWtP23M9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q86YP4 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-726224|uniprotkb:Q7L3J2|uniprotkb:Q96F28|uniprotkb:Q9NPU2|uniprotkb:Q9NXS1|uniprotkb:B5MC40|ensembl:ENSP00000351552|ensembl:ENSP00000353463 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:p66a_human(display_long)|uniprotkb:GATA zinc finger domain-containing protein 2A(gene name synonym)|uniprotkb:GATAD2A(gene name)|psi-mi:GATAD2A(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) refseq:NP_060130.3|refseq:NP_001287875.1|refseq:XP_011526407.1|ensembl:ENSG00000167491(gene)|ensembl:ENST00000358713(transcript)|ensembl:ENST00000360315(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR032346|interpro:IPR040386|mint:Q86YP4|rcsb pdb:2L2L|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|dip:DIP-36053N|uniprotkb:Q86YP4(identity)|entrezgene/locuslink:54815(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:s2G27yMihH9d7ny/v1GZ7aeTpDQ9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q13112 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-1052944|uniprotkb:Q99548|ensembl:ENSP00000315700 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:caf1b_human(display_long)|uniprotkb:Chromatin assembly factor I p60 subunit(gene name synonym)|uniprotkb:M-phase phosphoprotein 7(gene name synonym)|uniprotkb:CHAF1B(gene name)|psi-mi:CHAF1B(display_short)|uniprotkb:CAF1A(gene name synonym)|uniprotkb:CAF1P60(gene name synonym)|uniprotkb:MPHOSPH7(gene name synonym)|uniprotkb:MPP7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) refseq:NP_005432.1|dip:DIP-29243N|ensembl:ENSG00000159259(gene)|ensembl:ENST00000314103(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR029129|interpro:IPR036322|mint:Q13112|refseq:XP_016883966.1|refseq:XP_016883967.1|uniprotkb:Q13112(identity)|entrezgene/locuslink:8208(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:VVbW9mpUGYMRPxvlEk9FERHIsJs9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:O75446 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-632609|uniprotkb:D3DP38|ensembl:ENSP00000296504 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:sap30_human(display_long)|uniprotkb:30 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Sin3 corepressor complex subunit SAP30(gene name synonym)|uniprotkb:SAP30(gene name)|psi-mi:SAP30(display_short)|uniprotkb:Sin3-associated polypeptide p30(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) refseq:NP_003855.1|ensembl:ENSG00000164105(gene)|ensembl:ENST00000296504(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0052472"(modulation by host of symbiont transcription)|interpro:IPR024145|interpro:IPR025717|interpro:IPR025718|interpro:IPR038291|mint:O75446|rcsb pdb:2KDP|reactome:R-HSA-3214815|reactome:R-HSA-427413|reactome:R-HSA-9679191|dip:DIP-33328N|uniprotkb:O75446(identity)|entrezgene/locuslink:8819(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:w113AyekZAZr9VOJWcWEFIhqBYA9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:P84243 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-120658|uniprotkb:P06351|uniprotkb:P33155|uniprotkb:Q5VV55|uniprotkb:Q5VV56|uniprotkb:Q66I33|uniprotkb:Q9V3W4|ensembl:ENSP00000254810|ensembl:ENSP00000355778|ensembl:ENSP00000355780|ensembl:ENSP00000355781|ensembl:ENSP00000465813|ensembl:ENSP00000466020|ensembl:ENSP00000468714|ensembl:ENSP00000499275|ensembl:ENSP00000499385|ensembl:ENSP00000499800 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:h33_human(display_long)|uniprotkb:H3-3A(gene name)|psi-mi:H3-3A(display_short)|uniprotkb:H3-3B(gene name)|psi-mi:H3-3B(display_short)|uniprotkb:H3.3A(gene name synonym)|uniprotkb:H3.3B(gene name synonym)|uniprotkb:H3F3(gene name synonym)|uniprotkb:H3F3A(gene name synonym)|uniprotkb:H3F3B(gene name synonym)|uniprotkb:PP781(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8834818|imex:IM-21659-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|ddbj/embl/genbank:BC003092(identity)|entrezgene/locuslink:5928(identity) refseq:NP_002098.1|refseq:NP_005315.1|rcsb pdb:4H9N|rcsb pdb:3QL9|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:3QLA|rcsb pdb:3QLC|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4L58|rcsb pdb:4N4I|rcsb pdb:3WTP|rcsb pdb:4O62|rcsb pdb:4QQ4|rcsb pdb:4TMP|rcsb pdb:4GNE|rcsb pdb:4GNF|rcsb pdb:4U7T|rcsb pdb:4GNG|rcsb pdb:4W5A|rcsb pdb:4GU0|rcsb pdb:4GUR|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:4GUS|rcsb pdb:4GY5|rcsb pdb:5DWQ|rcsb pdb:5DX0|rcsb pdb:5JA4|rcsb pdb:5JJY|ensembl:ENSG00000132475(gene)|ensembl:ENSG00000163041(gene)|rcsb pdb:5JLB|rcsb pdb:5KDM|rcsb pdb:5X7X|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6HGT|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6J9J|rcsb pdb:6PZV|rcsb pdb:6QXZ|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6U04|rcsb pdb:7A08|reactome:R-HSA-427413|rcsb pdb:7CIZ|reactome:R-HSA-5250924|reactome:R-HSA-5334118|rcsb pdb:7CJ0|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-983231|rcsb pdb:7CWH|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-427359|reactome:R-HSA-427389|ensembl:ENST00000254810(transcript)|ensembl:ENST00000366813(transcript)|ensembl:ENST00000366815(transcript)|ensembl:ENST00000366816(transcript)|ensembl:ENST00000586607(transcript)|ensembl:ENST00000587560(transcript)|ensembl:ENST00000589599(transcript)|ensembl:ENST00000655399(transcript)|ensembl:ENST00000661429(transcript)|ensembl:ENST00000666609(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P84243|rcsb pdb:2L43|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3AV2|rcsb pdb:3JVK|rcsb pdb:3MUK|rcsb pdb:3MUL|dip:DIP-40046N|uniprotkb:P84243(identity)|entrezgene/locuslink:3021(identity)|entrezgene/locuslink:3020(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:cRqA5/IBNfIbbxAnbwLqzXip20I9606 intact-crc:9AC6B08E2849D7CA|rigid:UDHtm/B6FnND1bwVVSmwk+aZON4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:Q5PSV4 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-5666615|intact:EBI-11060846|uniprotkb:Q9BRI4|uniprotkb:A6NFW5|uniprotkb:A6NH45|uniprotkb:B2RD65|ensembl:ENSP00000216807 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:brm1l_human(display_long)|uniprotkb:BRMS1-homolog protein p40(gene name synonym)|uniprotkb:BRMS1-like protein p40(gene name synonym)|uniprotkb:BRMS1L(gene name)|psi-mi:BRMS1L(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835025|imex:IM-21659-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|ddbj/embl/genbank:BC114501(identity)|entrezgene/locuslink:5931(identity) refseq:XP_006720338.1|refseq:NP_115728.2|refseq:XP_016877193.1|refseq:XP_016877194.1|ensembl:ENSG00000100916(gene)|ensembl:ENST00000216807(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0016575"(histone deacetylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0070822"(Sin3-type complex)|interpro:IPR013907(Sds3-like)|mint:Q5PSV4|uniprotkb:Q5PSV4(identity)|entrezgene/locuslink:84312(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:jVvtmlOL9vQdYz5kAnOi6GksVng9606 intact-crc:0D2D2E859ED6DF53|rigid:ZvH96NCJKngCKNf8HtQujsD1ths false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:Q8WXI9 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-923440|uniprotkb:Q5VUR2|uniprotkb:Q7LG68|uniprotkb:Q9ULS0|uniprotkb:D3DUZ2|ensembl:ENSP00000357644|ensembl:ENSP00000458280|ensembl:ENSP00000489184 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:p66b_human(display_long)|uniprotkb:GATAD2B(gene name)|psi-mi:GATAD2B(display_short)|uniprotkb:KIAA1150(gene name synonym)|uniprotkb:p66/p68(gene name synonym)|uniprotkb:GATA zinc finger domain-containing protein 2B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835025|imex:IM-21659-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|ddbj/embl/genbank:BC114501(identity)|entrezgene/locuslink:5931(identity) refseq:NP_065750.1|refseq:XP_005245421.1|dip:DIP-36054N|ensembl:ENSG00000143614(gene)|ensembl:ENSG00000261992(gene)|ensembl:ENST00000368655(transcript)|ensembl:ENST00000576342(transcript)|ensembl:ENST00000634544(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR032346|interpro:IPR040386|mint:Q8WXI9|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|uniprotkb:Q8WXI9(identity)|entrezgene/locuslink:57459(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:pLKkMcJBBWdyMTf+2axWzvZLKP09606 intact-crc:0D2D2E859ED6DF53|rigid:ZvH96NCJKngCKNf8HtQujsD1ths false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:O94776 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-1783035|uniprotkb:Q68DB1|uniprotkb:Q9UQB5|ensembl:ENSP00000278823 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:mta2_human(display_long)|uniprotkb:MTA2(gene name)|psi-mi:MTA2(display_short)|uniprotkb:MTA1L1(gene name synonym)|uniprotkb:PID(gene name synonym)|uniprotkb:Metastasis-associated 1-like 1(gene name synonym)|uniprotkb:p53 target protein in deacetylase complex(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835025|imex:IM-21659-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|ddbj/embl/genbank:BC114501(identity)|entrezgene/locuslink:5931(identity) refseq:NP_004730.2|refseq:NP_001317221.1|dip:DIP-46519N|ensembl:ENSG00000149480(gene)|ensembl:ENST00000278823(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006306"(DNA methylation)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0016020"(membrane)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR035170|interpro:IPR037964|interpro:IPR040138|interpro:IPR043151|mint:O94776|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|uniprotkb:O94776(identity)|entrezgene/locuslink:9219(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:D4wOsdMJYhY/ltvcnnuMHqNrFkc9606 intact-crc:0D2D2E859ED6DF53|rigid:ZvH96NCJKngCKNf8HtQujsD1ths false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:Q9Y294 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-749553|uniprotkb:Q6IA08|uniprotkb:Q9P014|ensembl:ENSP00000229595 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:asf1a_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog A(gene name synonym)|uniprotkb:CCG1-interacting factor A(gene name synonym)|uniprotkb:ASF1A(gene name)|psi-mi:ASF1A(display_short)|uniprotkb:CGI-98(orf name)|uniprotkb:HSPC146(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835025|imex:IM-21659-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|ddbj/embl/genbank:BC114501(identity)|entrezgene/locuslink:5931(identity) refseq:NP_054753.1|dip:DIP-29241N|ensembl:ENSG00000111875(gene)|ensembl:ENST00000229595(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042692"(muscle cell differentiation)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9Y294|rcsb pdb:1TEY|rcsb pdb:2I32|rcsb pdb:2IIJ|rcsb pdb:2IO5|rcsb pdb:3AAD|rcsb pdb:5C3I|rcsb pdb:6F0G|rcsb pdb:6F0H|rcsb pdb:6ZUF|reactome:R-HSA-2559584|rcsb pdb:6F0F|uniprotkb:Q9Y294(identity)|entrezgene/locuslink:25842(identity) psi-mi:"MI:0469"(intact) - caution:This sequence has been withdrawn from Uniprot. figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:rIMptRSOYD+wfp0dMEHjhNNsHXQ9606 intact-crc:0D2D2E859ED6DF53|rigid:ZvH96NCJKngCKNf8HtQujsD1ths false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:Q96ST3 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-347218|uniprotkb:Q8N8N4|uniprotkb:Q8NC83|uniprotkb:Q8WV18|uniprotkb:Q96L98|uniprotkb:Q9UFQ1|intact:EBI-28985143|ensembl:ENSP00000353622|ensembl:ENSP00000378402|ensembl:ENSP00000378403|uniprotkb:B2RNS5 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:sin3a_human(display_long)|uniprotkb:SIN3A(gene name)|psi-mi:SIN3A(display_short)|uniprotkb:Transcriptional corepressor Sin3a(gene name synonym)|uniprotkb:Histone deacetylase complex subunit Sin3a(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835025|imex:IM-21659-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|ddbj/embl/genbank:BC114501(identity)|entrezgene/locuslink:5931(identity) refseq:XP_006720528.1|ensembl:ENSG00000169375(gene)|ensembl:ENST00000360439(transcript)|ensembl:ENST00000394947(transcript)|ensembl:ENST00000394949(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007568"(aging)|go:"GO:0010817"(regulation of hormone levels)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0031937"(obsolete positive regulation of chromatin silencing)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0051595"(response to methylglyoxal)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1901675"(negative regulation of histone H3-K27 acetylation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR013194(Histone deacetylase interacting)|interpro:IPR031693|interpro:IPR036600|interpro:IPR037969|interpro:IPR039774|mint:Q96ST3|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-427413|reactome:R-HSA-8936459|reactome:R-HSA-9022538|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9022702|rcsb pdb:1PO4|reactome:R-HSA-9615017|reactome:R-HSA-9707564|reactome:R-HSA-983231|refseq:XP_006720529.1|refseq:XP_006720530.1|refseq:NP_001138829.1|refseq:NP_001138830.1|refseq:NP_056292.1|ensembl:ENSP00000353622|ensembl:ENSP00000378402|ensembl:ENSP00000378403|dip:DIP-31515N|uniprotkb:Q96ST3(identity)|entrezgene/locuslink:25942(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:pO/FziDcMNQRfy6ePi6eNKELXVM9606 intact-crc:0D2D2E859ED6DF53|rigid:ZvH96NCJKngCKNf8HtQujsD1ths false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:O75446 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-632609|uniprotkb:D3DP38|ensembl:ENSP00000296504 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:sap30_human(display_long)|uniprotkb:30 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Sin3 corepressor complex subunit SAP30(gene name synonym)|uniprotkb:SAP30(gene name)|psi-mi:SAP30(display_short)|uniprotkb:Sin3-associated polypeptide p30(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835025|imex:IM-21659-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|ddbj/embl/genbank:BC114501(identity)|entrezgene/locuslink:5931(identity) refseq:NP_003855.1|ensembl:ENSG00000164105(gene)|ensembl:ENST00000296504(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0052472"(modulation by host of symbiont transcription)|interpro:IPR024145|interpro:IPR025717|interpro:IPR025718|interpro:IPR038291|mint:O75446|rcsb pdb:2KDP|reactome:R-HSA-3214815|reactome:R-HSA-427413|reactome:R-HSA-9679191|dip:DIP-33328N|uniprotkb:O75446(identity)|entrezgene/locuslink:8819(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:w113AyekZAZr9VOJWcWEFIhqBYA9606 intact-crc:0D2D2E859ED6DF53|rigid:ZvH96NCJKngCKNf8HtQujsD1ths false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:Q96N64 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-6597774|uniprotkb:Q2HJJ2|uniprotkb:Q8IYR3|uniprotkb:Q96PV3|uniprotkb:G5EA07|ensembl:ENSP00000305151 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:pwp2a_human(display_long)|uniprotkb:PWWP2A(gene name)|psi-mi:PWWP2A(display_short)|uniprotkb:KIAA1935(gene name synonym)|uniprotkb:MST101(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835025|imex:IM-21659-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|ddbj/embl/genbank:BC114501(identity)|entrezgene/locuslink:5931(identity) refseq:NP_001124336.1|refseq:NP_443159.1|refseq:NP_001253964.1|ensembl:ENSG00000170234(gene)|ensembl:ENST00000307063(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0042393"(histone binding)|interpro:IPR000313(PWWP)|mint:Q96N64|uniprotkb:Q96N64(identity)|entrezgene/locuslink:114825(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:dRVLcq751e3y+moSaAoqbKU++HQ9606 intact-crc:0D2D2E859ED6DF53|rigid:ZvH96NCJKngCKNf8HtQujsD1ths false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:A6NHQ4 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-8831125|ensembl:ENSP00000483859|ensembl:ENSP00000484710 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:epop_human(display_long)|uniprotkb:EPOP(gene name)|psi-mi:EPOP(display_short)|uniprotkb:C17orf96(gene name synonym)|uniprotkb:PRR28(gene name synonym)|uniprotkb:Proline-rich protein 28(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835025|imex:IM-21659-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|ddbj/embl/genbank:BC114501(identity)|entrezgene/locuslink:5931(identity) refseq:NP_001124149.1|ensembl:ENSG00000273604(gene)|ensembl:ENST00000613024(transcript)|ensembl:ENST00000621654(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005694"(chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0070449"(elongin complex)|interpro:IPR027971|mint:A6NHQ4|ensembl:ENSG00000277303(gene)|uniprotkb:A6NHQ4(identity)|entrezgene/locuslink:100170841(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:xxrapCjRxgY22pLac2F4zSS2bvk9606 intact-crc:0D2D2E859ED6DF53|rigid:ZvH96NCJKngCKNf8HtQujsD1ths false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:Q09028 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835025|imex:IM-21659-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|ddbj/embl/genbank:BC114501(identity)|entrezgene/locuslink:5931(identity) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|entrezgene/locuslink:5928(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 intact-crc:0D2D2E859ED6DF53|rigid:ZvH96NCJKngCKNf8HtQujsD1ths false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:Q9HCU9 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-714781|uniprotkb:Q6IAI2|ensembl:ENSP00000353042 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:brms1_human(display_long)|uniprotkb:BRMS1(gene name)|psi-mi:BRMS1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835025|imex:IM-21659-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|ddbj/embl/genbank:BC114501(identity)|entrezgene/locuslink:5931(identity) ensembl:ENSG00000174744(gene)|ensembl:ENST00000359957(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0016575"(histone deacetylation)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0070822"(Sin3-type complex)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:2000210"(positive regulation of anoikis)|interpro:IPR013907(Sds3-like)|rcsb pdb:2XUS|rcsb pdb:4AUV|reactome:R-HSA-3214815|reactome:R-HSA-9679191|refseq:NP_056214.1|dip:DIP-24250N|uniprotkb:Q9HCU9(identity)|entrezgene/locuslink:25855(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:kuaR4dVP6xzSOMHwSd+CDrLU/uo9606 intact-crc:0D2D2E859ED6DF53|rigid:ZvH96NCJKngCKNf8HtQujsD1ths false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:O14929 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-2339359|uniprotkb:Q53SU4|uniprotkb:Q53QF0|uniprotkb:Q49A44|uniprotkb:Q6P594|uniprotkb:Q8WWB9|ensembl:ENSP00000264108 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:hat1_human(display_long)|uniprotkb:HAT1(gene name)|psi-mi:HAT1(display_short)|uniprotkb:KAT1(gene name synonym)|uniprotkb:Histone acetyltransferase 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835025|imex:IM-21659-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|ddbj/embl/genbank:BC114501(identity)|entrezgene/locuslink:5931(identity) refseq:NP_003633.1|dip:DIP-52811N|ensembl:ENSG00000128708(gene)|ensembl:ENST00000264108(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006323"(DNA packaging)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006348"|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0007584"(response to nutrient)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR013523(Histone acetyltransferase HAT1, C-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017380(Histone acetyltransferase type B, catalytic subunit)|interpro:IPR019467|interpro:IPR037113|mint:O14929|rcsb pdb:2P0W|rcsb pdb:6VO5|reactome:R-HSA-3214847|uniprotkb:O14929(identity)|entrezgene/locuslink:8520(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:80KgRaid3NeRfAUdTHMQ/r0VuGo9606 intact-crc:0D2D2E859ED6DF53|rigid:ZvH96NCJKngCKNf8HtQujsD1ths false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:Q13330 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-714236|uniprotkb:Q8NFI8|uniprotkb:Q96GI8|uniprotkb:A5PLK4|intact:EBI-28976623|ensembl:ENSP00000333633|uniprotkb:Q86SW2 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:mta1_human(display_long)|uniprotkb:MTA1(gene name)|psi-mi:MTA1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835025|imex:IM-21659-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|ddbj/embl/genbank:BC114501(identity)|entrezgene/locuslink:5931(identity) refseq:NP_001190187.1|refseq:NP_004680.2|ensembl:ENSP00000333633|ensembl:ENST00000405646|ensembl:ENSP00000384180|ensembl:ENST00000438610|ensembl:ENSP00000393438|ensembl:ENSG00000182979(gene)|ensembl:ENST00000331320(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|reactome:R-HSA-427389|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|reactome:R-HSA-3232118|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR035170|interpro:IPR040138|mint:Q13330|rcsb pdb:4BKX|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:5FXY|rcsb pdb:5ICN|rcsb pdb:6G16|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AO8|go:"GO:0045475"(locomotor rhythm)|rcsb pdb:7AO9|rcsb pdb:7AOA|reactome:R-HSA-3214815|dip:DIP-41751N|uniprotkb:Q13330(identity)|entrezgene/locuslink:9112(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:nDDSb5B6YCbq5/6qvgtnUWtP23M9606 intact-crc:0D2D2E859ED6DF53|rigid:ZvH96NCJKngCKNf8HtQujsD1ths false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:Q9UBB5 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-923391|uniprotkb:Q9UIS8|uniprotkb:O95242|ensembl:ENSP00000256429 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:mbd2_human(display_long)|uniprotkb:MBD2(gene name)|psi-mi:MBD2(display_short)|uniprotkb:Methyl-CpG-binding protein MBD2(gene name synonym)|uniprotkb:Demethylase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835025|imex:IM-21659-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|ddbj/embl/genbank:BC114501(identity)|entrezgene/locuslink:5931(identity) refseq:NP_003918.1|refseq:NP_056647.1|ensembl:ENSG00000134046(gene)|ensembl:ENST00000256429(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003696"(satellite DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034622"|go:"GO:0035197"(siRNA binding)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042711"(maternal behavior)|go:"GO:0043044"|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048568"(embryonic organ development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR025884|interpro:IPR032343|mint:Q9UBB5|rcsb pdb:2L2L|rcsb pdb:6C1A|rcsb pdb:6C1T|rcsb pdb:6C1U|rcsb pdb:6C1V|rcsb pdb:6C2F|rcsb pdb:6CNP|rcsb pdb:6CNQ|rcsb pdb:7AO8|rcsb pdb:7AO9|rcsb pdb:7AOA|reactome:R-HSA-427413|reactome:R-HSA-73728|uniprotkb:Q9UBB5(identity)|entrezgene/locuslink:8932(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:8DO+M6oIpbSfTFPVLADdXaaqzEU9606 intact-crc:0D2D2E859ED6DF53|rigid:ZvH96NCJKngCKNf8HtQujsD1ths false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:P62891 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-8830744|uniprotkb:P02404|uniprotkb:Q9BYF2|uniprotkb:P39025|ensembl:ENSP00000355315 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:rl39_human(display_long)|uniprotkb:RPL39(gene name)|psi-mi:RPL39(display_short)|uniprotkb:Large ribosomal subunit protein eL39(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835025|imex:IM-21659-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|ddbj/embl/genbank:BC114501(identity)|entrezgene/locuslink:5931(identity) refseq:NP_000991.1|rcsb pdb:4V6X|ensembl:ENSG00000198918(gene)|ensembl:ENST00000361575(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000077(Ribosomal protein L39e)|interpro:IPR020083|interpro:IPR023626|rcsb pdb:4UG0|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|uniprotkb:P62891(identity)|entrezgene/locuslink:6170(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:AZus2dxwJsTxAOwnJ93E2yhasbo9606 intact-crc:0D2D2E859ED6DF53|rigid:ZvH96NCJKngCKNf8HtQujsD1ths false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:Q9Y483 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-725816|uniprotkb:A6NGQ9|uniprotkb:Q9UES9|uniprotkb:Q9UP40|uniprotkb:A8K2Q3|uniprotkb:B1AKT5|intact:EBI-11028207|uniprotkb:Q96G26|uniprotkb:B1AKT6|ensembl:ENSP00000359321 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:mtf2_human(display_long)|uniprotkb:PCL2(gene name synonym)|uniprotkb:Metal-response element DNA-binding protein M96(gene name synonym)|uniprotkb:Metal regulatory transcription factor 2(gene name synonym)|uniprotkb:Polycomb-like protein 2(gene name synonym)|uniprotkb:MTF2(gene name)|psi-mi:MTF2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835025|imex:IM-21659-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|ddbj/embl/genbank:BC114501(identity)|entrezgene/locuslink:5931(identity) refseq:NP_001157863.1|refseq:NP_001157865.1|refseq:NP_031384.1|refseq:XP_011539318.1|refseq:XP_016856165.1|ensembl:ENSG00000143033(gene)|ensembl:ENST00000370298(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042015|mint:Q9Y483|rcsb pdb:5XFR|reactome:R-HSA-212300|interpro:IPR042014|refseq:NP_001157864.1|uniprotkb:Q9Y483(identity)|entrezgene/locuslink:22823(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:Im8E6U/OPb8AEir43AUUDlU6F2o9606 intact-crc:0D2D2E859ED6DF53|rigid:ZvH96NCJKngCKNf8HtQujsD1ths false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:O15212 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-356973|ensembl:ENSP00000363734|ensembl:ENSP00000363735|ensembl:ENSP00000363738|ensembl:ENSP00000372694|ensembl:ENSP00000378563|ensembl:ENSP00000382314|ensembl:ENSP00000382316|ensembl:ENSP00000395462|ensembl:ENSP00000398171|ensembl:ENSP00000400152|ensembl:ENSP00000402212|ensembl:ENSP00000402553|ensembl:ENSP00000403771|ensembl:ENSP00000404773|ensembl:ENSP00000412319|ensembl:ENSP00000415678|ensembl:ENSP00000447540|ensembl:ENSP00000448607|ensembl:ENSP00000448784|ensembl:ENSP00000449925 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:pfd6_human(display_long)|uniprotkb:PFDN6(gene name)|psi-mi:PFDN6(display_short)|uniprotkb:HKE2(gene name synonym)|uniprotkb:PFD6(gene name synonym)|uniprotkb:Protein Ke2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835025|imex:IM-21659-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|ddbj/embl/genbank:BC114501(identity)|entrezgene/locuslink:5931(identity) refseq:NP_001172110.1|refseq:NP_055075.1|refseq:NP_001252524.1|refseq:NP_001252525.1|dip:DIP-50304N|ensembl:ENSG00000204220(gene)|ensembl:ENSG00000206283(gene)|ensembl:ENSG00000224782(gene)|ensembl:ENSG00000235692(gene)|ensembl:ENSG00000237335(gene)|ensembl:ENST00000374606(transcript)|ensembl:ENST00000374607(transcript)|ensembl:ENST00000374610(transcript)|ensembl:ENST00000383207(transcript)|ensembl:ENST00000395131(transcript)|ensembl:ENST00000399383(transcript)|ensembl:ENST00000399385(transcript)|ensembl:ENST00000412289(transcript)|ensembl:ENST00000425878(transcript)|ensembl:ENST00000431830(transcript)|ensembl:ENST00000432391(transcript)|ensembl:ENST00000442285(transcript)|ensembl:ENST00000445559(transcript)|ensembl:ENST00000448594(transcript)|ensembl:ENST00000451970(transcript)|ensembl:ENST00000452658(transcript)|ensembl:ENST00000547641(transcript)|ensembl:ENST00000547952(transcript)|ensembl:ENST00000548040(transcript)|ensembl:ENST00000552711(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|mint:O15212|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957|uniprotkb:O15212(identity)|entrezgene/locuslink:10471(identity) psi-mi:"MI:0469"(intact) - crc64:8F138EAAE512A312 figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:t7Z68vuvmprxLIGDh4JhqCGvX+A9606 intact-crc:0D2D2E859ED6DF53|rigid:ZvH96NCJKngCKNf8HtQujsD1ths false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:Q86YP4 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-726224|uniprotkb:Q7L3J2|uniprotkb:Q96F28|uniprotkb:Q9NPU2|uniprotkb:Q9NXS1|uniprotkb:B5MC40|ensembl:ENSP00000351552|ensembl:ENSP00000353463 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:p66a_human(display_long)|uniprotkb:GATA zinc finger domain-containing protein 2A(gene name synonym)|uniprotkb:GATAD2A(gene name)|psi-mi:GATAD2A(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835025|imex:IM-21659-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|ddbj/embl/genbank:BC114501(identity)|entrezgene/locuslink:5931(identity) refseq:NP_060130.3|refseq:NP_001287875.1|refseq:XP_011526407.1|ensembl:ENSG00000167491(gene)|ensembl:ENST00000358713(transcript)|ensembl:ENST00000360315(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR032346|interpro:IPR040386|mint:Q86YP4|rcsb pdb:2L2L|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|dip:DIP-36053N|uniprotkb:Q86YP4(identity)|entrezgene/locuslink:54815(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:s2G27yMihH9d7ny/v1GZ7aeTpDQ9606 intact-crc:0D2D2E859ED6DF53|rigid:ZvH96NCJKngCKNf8HtQujsD1ths false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:O75182 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-540462|uniprotkb:Q68GC2|uniprotkb:Q6P4B8|uniprotkb:Q8TB34|uniprotkb:Q9BSC8|uniprotkb:Q2NL91|ensembl:ENSP00000369131 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:sin3b_human(display_long)|uniprotkb:Transcriptional corepressor Sin3b(gene name synonym)|uniprotkb:Histone deacetylase complex subunit Sin3b(gene name synonym)|uniprotkb:SIN3B(gene name)|psi-mi:SIN3B(display_short)|uniprotkb:KIAA0700(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835025|imex:IM-21659-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|ddbj/embl/genbank:BC114501(identity)|entrezgene/locuslink:5931(identity) refseq:NP_056075.1|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0030849"(autosome)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR013194(Histone deacetylase interacting)|interpro:IPR031693|go:"GO:0003682"(chromatin binding)|interpro:IPR036600|interpro:IPR039774|mint:O75182|reactome:R-HSA-400206|reactome:R-HSA-427413|reactome:R-HSA-8936459|reactome:R-HSA-9707564|ensembl:ENSG00000127511(gene)|ensembl:ENST00000379803(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000805"(X chromosome)|go:"GO:0000806"(Y chromosome)|go:"GO:0001741"(XY body)|refseq:NP_001284524.1|refseq:NP_001284526.1|uniprotkb:O75182(identity)|entrezgene/locuslink:23309(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:ney2nq8TMh2sFxskgXr+NgNCl349606 intact-crc:0D2D2E859ED6DF53|rigid:ZvH96NCJKngCKNf8HtQujsD1ths false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:Q12873 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-523590|uniprotkb:Q9Y4I0|intact:EBI-28978117|ensembl:ENSP00000332628|uniprotkb:D3DTQ9|uniprotkb:E9PG89 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:chd3_human(display_long)|uniprotkb:ATP-dependent helicase CHD3(gene name synonym)|uniprotkb:Mi-2 autoantigen 240 kDa protein(gene name synonym)|uniprotkb:Mi2-alpha(gene name synonym)|uniprotkb:Zinc finger helicase(gene name synonym)|uniprotkb:CHD3(gene name)|psi-mi:CHD3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835025|imex:IM-21659-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|ddbj/embl/genbank:BC114501(identity)|entrezgene/locuslink:5931(identity) interpro:IPR023780|interpro:IPR027417|interpro:IPR036910|interpro:IPR038718|mint:Q12873|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-4551638|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|ensembl:ENSG00000170004(gene)|ensembl:ENST00000330494(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007051"(spindle organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0016605"(PML body)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036121"(double-stranded DNA helicase activity)|go:"GO:0043044"|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|go:"GO:0070615"|interpro:IPR019787|interpro:IPR023779|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|ensembl:ENSP00000332628|ensembl:ENST00000358181|ensembl:ENSP00000350907|ensembl:ENST00000380358|ensembl:ENSP00000369716|refseq:NP_001005271.2|refseq:NP_001005273.1|refseq:NP_005843.2|dip:DIP-32496N|uniprotkb:Q12873(identity)|entrezgene/locuslink:1107(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:UjefFUXiV28qhOP9BoIUansxl+k9606 intact-crc:0D2D2E859ED6DF53|rigid:ZvH96NCJKngCKNf8HtQujsD1ths false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:Q9NVP2 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-1055650|uniprotkb:Q53G51|uniprotkb:Q9NVZ0|ensembl:ENSP00000263382|ensembl:ENSP00000499863 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:asf1b_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog B(gene name synonym)|uniprotkb:CCG1-interacting factor A-II(gene name synonym)|uniprotkb:ASF1B(gene name)|psi-mi:ASF1B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835025|imex:IM-21659-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|ddbj/embl/genbank:BC114501(identity)|entrezgene/locuslink:5931(identity) refseq:NP_060624.1|ensembl:ENSG00000105011(gene)|ensembl:ENSG00000288210(gene)|ensembl:ENST00000263382(transcript)|ensembl:ENST00000672225(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9NVP2|rcsb pdb:5BNX|rcsb pdb:5BO0|dip:DIP-29242N|uniprotkb:Q9NVP2(identity)|entrezgene/locuslink:55723(identity) psi-mi:"MI:0469"(intact) - caution:This sequence has been withdrawn from Uniprot. figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:gG2Px6QOw95EohRaaWivH7GrSr09606 intact-crc:0D2D2E859ED6DF53|rigid:ZvH96NCJKngCKNf8HtQujsD1ths false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:Q15022 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835025|imex:IM-21659-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|ddbj/embl/genbank:BC114501(identity)|entrezgene/locuslink:5931(identity) dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:Q15022(identity)|entrezgene/locuslink:23512(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 intact-crc:0D2D2E859ED6DF53|rigid:ZvH96NCJKngCKNf8HtQujsD1ths false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:Q9H165 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-765567|uniprotkb:Q86W14|uniprotkb:Q8WU92|uniprotkb:Q96JL6|uniprotkb:Q9H163|uniprotkb:Q9H164|uniprotkb:Q9H3G9|uniprotkb:Q9NWA7|uniprotkb:D6W5D7|uniprotkb:Q66LN6|ensembl:ENSP00000496168 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:bc11a_human(display_long)|uniprotkb:B-cell CLL/lymphoma 11A(gene name synonym)|uniprotkb:COUP-TF-interacting protein 1(gene name synonym)|uniprotkb:Ecotropic viral integration site 9 protein homolog(gene name synonym)|uniprotkb:BCL11A(gene name)|psi-mi:BCL11A(display_short)|uniprotkb:CTIP1(gene name synonym)|uniprotkb:EVI9(gene name synonym)|uniprotkb:KIAA1809(gene name synonym)|uniprotkb:ZNF856(gene name synonym)|uniprotkb:Zinc finger protein 856(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835025|imex:IM-21659-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|ddbj/embl/genbank:BC114501(identity)|entrezgene/locuslink:5931(identity) refseq:NP_060484.2|refseq:NP_075044.2|refseq:NP_612569.1|refseq:XP_011531211.1|refseq:XP_016859823.1|dip:DIP-45629N|ensembl:ENSG00000119866(gene)|ensembl:ENST00000642384(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001067"(transcription regulatory region nucleic acid binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0032463"(negative regulation of protein homooligomerization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048672"(positive regulation of collateral sprouting)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:1903860"(negative regulation of dendrite extension)|go:"GO:1904800"(negative regulation of neuron remodeling)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9H165|rcsb pdb:5VTB|rcsb pdb:6KI6|rcsb pdb:6U9Q|go:"GO:2000173"(negative regulation of branching morphogenesis of a nerve)|uniprotkb:Q9H165(identity)|entrezgene/locuslink:53335(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:xASsLQWykg/7ZpyjLsQP8GlQ/H09606 intact-crc:0D2D2E859ED6DF53|rigid:ZvH96NCJKngCKNf8HtQujsD1ths false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:O60684 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-359923|uniprotkb:Q5VVU3|uniprotkb:B2RDC7|ensembl:ENSP00000362728|uniprotkb:D3DPP5 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:ima7_human(display_long)|uniprotkb:KPNA6(gene name)|psi-mi:KPNA6(display_short)|uniprotkb:IPOA7(gene name synonym)|uniprotkb:Karyopherin subunit alpha-6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835025|imex:IM-21659-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|ddbj/embl/genbank:BC114501(identity)|entrezgene/locuslink:5931(identity) refseq:NP_036448.1|ensembl:ENSG00000025800(gene)|ensembl:ENST00000373625(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0019079"(viral genome replication)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0043657"(host cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O60684|rcsb pdb:4UAD|dip:DIP-27609N|uniprotkb:O60684(identity)|entrezgene/locuslink:23633(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:3NsSIcE6BHIqYlvfGRolUKD/5uc9606 intact-crc:0D2D2E859ED6DF53|rigid:ZvH96NCJKngCKNf8HtQujsD1ths false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:Q5T6S3 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-2339674|uniprotkb:Q6N038|uniprotkb:Q32NF2|uniprotkb:Q8TBL6|uniprotkb:Q5T6S4|uniprotkb:Q9UFS9|ensembl:ENSP00000363003 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:phf19_human(display_long)|uniprotkb:PHF19(gene name)|psi-mi:PHF19(display_short)|uniprotkb:PCL3(gene name synonym)|uniprotkb:Polycomb-like protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835025|imex:IM-21659-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|ddbj/embl/genbank:BC114501(identity)|entrezgene/locuslink:5931(identity) refseq:XP_011516811.1|refseq:NP_001009936.1|refseq:NP_056466.1|refseq:NP_001273769.1|refseq:NP_001273772.1|refseq:XP_005251963.1|refseq:XP_016870101.1|ensembl:ENSG00000119403(gene)|ensembl:ENST00000373896(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042017|mint:Q5T6S3|rcsb pdb:2E5Q|rcsb pdb:4BD3|rcsb pdb:6NQ3|rcsb pdb:6WAU|reactome:R-HSA-212300|uniprotkb:Q5T6S3(identity)|entrezgene/locuslink:26147(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:K4sKpUT1htSiigJaEoGyDjvkWqc9606 intact-crc:0D2D2E859ED6DF53|rigid:ZvH96NCJKngCKNf8HtQujsD1ths false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:Q8WUU4 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-8834821|ensembl:ENSP00000302770 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:zn296_human(display_long)|uniprotkb:ZNF342(gene name synonym)|uniprotkb:Zinc finger protein 342(gene name synonym)|uniprotkb:ZNF296(gene name)|psi-mi:ZNF296(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835025|imex:IM-21659-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|ddbj/embl/genbank:BC114501(identity)|entrezgene/locuslink:5931(identity) refseq:NP_660331.1|ensembl:ENSG00000170684(gene)|ensembl:ENST00000303809(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|uniprotkb:Q8WUU4(identity)|entrezgene/locuslink:162979(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:vjlS3Ns4JBJHA8afh2dI6dd+Nsk9606 intact-crc:0D2D2E859ED6DF53|rigid:ZvH96NCJKngCKNf8HtQujsD1ths false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:Q15910 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835025|imex:IM-21659-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|ddbj/embl/genbank:BC114501(identity)|entrezgene/locuslink:5931(identity) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N|uniprotkb:Q15910(identity)|entrezgene/locuslink:2146(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 intact-crc:0D2D2E859ED6DF53|rigid:ZvH96NCJKngCKNf8HtQujsD1ths false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:Q13547 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-301834|uniprotkb:Q92534|ensembl:ENSP00000362649 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:hdac1_human(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:RPD3L1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835025|imex:IM-21659-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|ddbj/embl/genbank:BC114501(identity)|entrezgene/locuslink:5931(identity) ensembl:ENSG00000116478(gene)|ensembl:ENST00000373548(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007492"(endoderm development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031000"(response to caffeine)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043044"|go:"GO:0019213"(deacetylase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900221"(regulation of amyloid-beta clearance)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q13547|rcsb pdb:1TYI|rcsb pdb:4BKX|rcsb pdb:5ICN|rcsb pdb:6Z2J|rcsb pdb:6Z2K|rcsb pdb:7AO8|rcsb pdb:7AO9|rcsb pdb:7AOA|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-193670|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-3769402|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-4641265|reactome:R-HSA-6804758|reactome:R-HSA-69205|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9022538|reactome:R-HSA-9022692|go:"GO:0017053"(transcription repressor complex)|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9615017|reactome:R-HSA-9679191|reactome:R-HSA-983231|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:NP_004955.2|dip:DIP-24184N|uniprotkb:Q13547(identity)|entrezgene/locuslink:3065(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:RP+yIBWH55NgoPTY1nKXqeJL/xY9606 intact-crc:0D2D2E859ED6DF53|rigid:ZvH96NCJKngCKNf8HtQujsD1ths false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:P84243 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-120658|uniprotkb:P06351|uniprotkb:P33155|uniprotkb:Q5VV55|uniprotkb:Q5VV56|uniprotkb:Q66I33|uniprotkb:Q9V3W4|ensembl:ENSP00000254810|ensembl:ENSP00000355778|ensembl:ENSP00000355780|ensembl:ENSP00000355781|ensembl:ENSP00000465813|ensembl:ENSP00000466020|ensembl:ENSP00000468714|ensembl:ENSP00000499275|ensembl:ENSP00000499385|ensembl:ENSP00000499800 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:h33_human(display_long)|uniprotkb:H3-3A(gene name)|psi-mi:H3-3A(display_short)|uniprotkb:H3-3B(gene name)|psi-mi:H3-3B(display_short)|uniprotkb:H3.3A(gene name synonym)|uniprotkb:H3.3B(gene name synonym)|uniprotkb:H3F3(gene name synonym)|uniprotkb:H3F3A(gene name synonym)|uniprotkb:H3F3B(gene name synonym)|uniprotkb:PP781(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835025|imex:IM-21659-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|ddbj/embl/genbank:BC114501(identity)|entrezgene/locuslink:5931(identity) refseq:NP_002098.1|refseq:NP_005315.1|rcsb pdb:4H9N|rcsb pdb:3QL9|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:3QLA|rcsb pdb:3QLC|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4L58|rcsb pdb:4N4I|rcsb pdb:3WTP|rcsb pdb:4O62|rcsb pdb:4QQ4|rcsb pdb:4TMP|rcsb pdb:4GNE|rcsb pdb:4GNF|rcsb pdb:4U7T|rcsb pdb:4GNG|rcsb pdb:4W5A|rcsb pdb:4GU0|rcsb pdb:4GUR|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:4GUS|rcsb pdb:4GY5|rcsb pdb:5DWQ|rcsb pdb:5DX0|rcsb pdb:5JA4|rcsb pdb:5JJY|ensembl:ENSG00000132475(gene)|ensembl:ENSG00000163041(gene)|rcsb pdb:5JLB|rcsb pdb:5KDM|rcsb pdb:5X7X|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6HGT|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6J9J|rcsb pdb:6PZV|rcsb pdb:6QXZ|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6U04|rcsb pdb:7A08|reactome:R-HSA-427413|rcsb pdb:7CIZ|reactome:R-HSA-5250924|reactome:R-HSA-5334118|rcsb pdb:7CJ0|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-983231|rcsb pdb:7CWH|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-427359|reactome:R-HSA-427389|ensembl:ENST00000254810(transcript)|ensembl:ENST00000366813(transcript)|ensembl:ENST00000366815(transcript)|ensembl:ENST00000366816(transcript)|ensembl:ENST00000586607(transcript)|ensembl:ENST00000587560(transcript)|ensembl:ENST00000589599(transcript)|ensembl:ENST00000655399(transcript)|ensembl:ENST00000661429(transcript)|ensembl:ENST00000666609(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P84243|rcsb pdb:2L43|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3AV2|rcsb pdb:3JVK|rcsb pdb:3MUK|rcsb pdb:3MUL|dip:DIP-40046N|uniprotkb:P84243(identity)|entrezgene/locuslink:3021(identity)|entrezgene/locuslink:3020(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:cRqA5/IBNfIbbxAnbwLqzXip20I9606 intact-crc:0D2D2E859ED6DF53|rigid:ZvH96NCJKngCKNf8HtQujsD1ths false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:Q9BQE3 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835025|imex:IM-21659-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|ddbj/embl/genbank:BC114501(identity)|entrezgene/locuslink:5931(identity) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1|uniprotkb:Q9BQE3(identity)|entrezgene/locuslink:84790(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:0D2D2E859ED6DF53|rigid:ZvH96NCJKngCKNf8HtQujsD1ths false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:O14519 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-1052532|uniprotkb:F5GYA4|intact:EBI-10988349|ensembl:ENSP00000261692 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:cdka1_human(display_long)|uniprotkb:Putative oral cancer suppressor(gene name synonym)|uniprotkb:Deleted in oral cancer 1(gene name synonym)|uniprotkb:CDK2AP1(gene name)|psi-mi:CDK2AP1(display_short)|uniprotkb:CDKAP1(gene name synonym)|uniprotkb:DOC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835025|imex:IM-21659-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|ddbj/embl/genbank:BC114501(identity)|entrezgene/locuslink:5931(identity) refseq:NP_004633.1|refseq:NP_001257362.1|refseq:NP_001257363.1|ensembl:ENSG00000111328(gene)|ensembl:ENST00000261692(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0007049"(cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070182"(DNA polymerase binding)|interpro:IPR017266(Cyclin-dependent kinase 2-associated protein 2)|mint:O14519|rcsb pdb:2KW6|uniprotkb:O14519(identity)|entrezgene/locuslink:8099(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:ZFfQSqkET3VpjG8UrdHokYRGzj09606 intact-crc:0D2D2E859ED6DF53|rigid:ZvH96NCJKngCKNf8HtQujsD1ths false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:Q9BTC8 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-2461787|uniprotkb:Q9NSP2|uniprotkb:Q9ULF4|ensembl:ENSP00000385823 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:mta3_human(display_long)|uniprotkb:MTA3(gene name)|psi-mi:MTA3(display_short)|uniprotkb:KIAA1266(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835025|imex:IM-21659-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|ddbj/embl/genbank:BC114501(identity)|entrezgene/locuslink:5931(identity) refseq:NP_001269684.1|refseq:NP_001269685.1|refseq:NP_065795.1|refseq:NP_001317371.1|dip:DIP-47460N|ensembl:ENST00000405094(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR035170|interpro:IPR040138|interpro:IPR043151|mint:Q9BTC8|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|ensembl:ENSG00000057935(gene)|uniprotkb:Q9BTC8(identity)|entrezgene/locuslink:57504(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:wxPsfH6FguY8n4PFwaj1iJNTWPc9606 intact-crc:0D2D2E859ED6DF53|rigid:ZvH96NCJKngCKNf8HtQujsD1ths false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:Q9HAJ7 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-2340040|uniprotkb:E9PAU7|uniprotkb:E9PAY2|ensembl:ENSP00000297109 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:sp30l_human(display_long)|uniprotkb:SAP30L(gene name)|psi-mi:SAP30L(display_short)|uniprotkb:NS4ATP2(gene name synonym)|uniprotkb:Sin3-associated protein p30-like(gene name synonym)|uniprotkb:Sin3 corepressor complex subunit SAP30L(gene name synonym)|uniprotkb:HCV non-structural protein 4A-transactivated protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835025|imex:IM-21659-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|ddbj/embl/genbank:BC114501(identity)|entrezgene/locuslink:5931(identity) refseq:NP_001124534.1|refseq:NP_001124535.1|refseq:NP_078908.1|ensembl:ENSG00000164576(gene)|ensembl:ENST00000297109(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0042393"(histone binding)|go:"GO:0044378"(non-sequence-specific DNA binding, bending)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|interpro:IPR024145|interpro:IPR025717|interpro:IPR025718|interpro:IPR038291|rcsb pdb:2N1U|reactome:R-HSA-3214815|reactome:R-HSA-427413|reactome:R-HSA-9679191|uniprotkb:Q9HAJ7(identity)|entrezgene/locuslink:79685(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:P+sxdU4GuYQwPnJPJSsBUwF6VnY9606 intact-crc:0D2D2E859ED6DF53|rigid:ZvH96NCJKngCKNf8HtQujsD1ths false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:Q9NP50 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-741906|ensembl:ENSP00000337477|ensembl:ENSP00000393279|ensembl:ENSP00000479093|ensembl:ENSP00000488570|uniprotkb:Q9BSZ8|uniprotkb:D3DUV8 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:shcaf_human(display_long)|uniprotkb:SINHCAF(gene name)|psi-mi:SINHCAF(display_short)|uniprotkb:C12orf14(gene name synonym)|uniprotkb:FAM60A(gene name synonym)|uniprotkb:Protein FAM60A(gene name synonym)|uniprotkb:Tera protein homolog(gene name synonym)|uniprotkb:L4(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835025|imex:IM-21659-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|ddbj/embl/genbank:BC114501(identity)|entrezgene/locuslink:5931(identity) ensembl:ENSG00000139146(gene)|ensembl:ENSG00000276371(gene)|ensembl:ENST00000337682(transcript)|ensembl:ENST00000454658(transcript)|ensembl:ENST00000617411(transcript)|ensembl:ENST00000633702(transcript)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0045596"(negative regulation of cell differentiation)|interpro:IPR026065|mint:Q9NP50|refseq:NP_001129283.1|refseq:NP_001129284.1|refseq:NP_067061.1|refseq:XP_016875247.1|refseq:XP_016875248.1|refseq:XP_016875249.1|refseq:XP_016875250.1|refseq:XP_016875251.1|uniprotkb:Q9NP50(identity)|entrezgene/locuslink:58516(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:LVESO8KQhobNYQduBQ/iAmNaNTM9606 intact-crc:0D2D2E859ED6DF53|rigid:ZvH96NCJKngCKNf8HtQujsD1ths false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:O95983 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-1783068|uniprotkb:Q6PIL9|uniprotkb:Q6PJZ9|uniprotkb:Q86XF4|uniprotkb:A8K4B7|uniprotkb:D6W5Z2|ensembl:ENSP00000412302 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:mbd3_human(display_long)|uniprotkb:MBD3(gene name)|psi-mi:MBD3(display_short)|uniprotkb:Methyl-CpG-binding protein MBD3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835025|imex:IM-21659-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|ddbj/embl/genbank:BC114501(identity)|entrezgene/locuslink:5931(identity) refseq:NP_001268382.1|refseq:NP_001268383.1|dip:DIP-46517N|ensembl:ENSG00000071655(gene)|ensembl:ENST00000434436(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0009888"(tissue development)|go:"GO:0016573"(histone acetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0048568"(embryonic organ development)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR025884|interpro:IPR032343|interpro:IPR037965|mint:O95983|rcsb pdb:2MB7|rcsb pdb:6CC8|rcsb pdb:6CCG|rcsb pdb:6CEU|rcsb pdb:6CEV|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|uniprotkb:O95983(identity)|entrezgene/locuslink:53615(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:lm8jh0YVLdljXDhjkTm9B1YSsWA9606 intact-crc:0D2D2E859ED6DF53|rigid:ZvH96NCJKngCKNf8HtQujsD1ths false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:O75530 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835025|imex:IM-21659-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|ddbj/embl/genbank:BC114501(identity)|entrezgene/locuslink:5931(identity) refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:O75530(identity)|entrezgene/locuslink:8726(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 intact-crc:0D2D2E859ED6DF53|rigid:ZvH96NCJKngCKNf8HtQujsD1ths false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:Q92769 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-301821|uniprotkb:Q5SRI8|uniprotkb:Q5SZ86|uniprotkb:Q8NEH4|uniprotkb:B4DL58|ensembl:ENSP00000430432|uniprotkb:E1P561|uniprotkb:B3KRS5 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:hdac2_human(display_long)|uniprotkb:HDAC2(gene name)|psi-mi:HDAC2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835025|imex:IM-21659-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|ddbj/embl/genbank:BC114501(identity)|entrezgene/locuslink:5931(identity) go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035094"(response to nicotine)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042220"(response to cocaine)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q92769|rcsb pdb:3MAX|rcsb pdb:4LXZ|rcsb pdb:4LY1|rcsb pdb:5IWG|rcsb pdb:5IX0|rcsb pdb:6G3O|rcsb pdb:6WBW|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000196591(gene)|ensembl:ENST00000519065(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|rcsb pdb:6WHN|rcsb pdb:6WHO|rcsb pdb:6WHQ|rcsb pdb:6WHZ|rcsb pdb:6WI3|rcsb pdb:6XDM|rcsb pdb:6XEB|rcsb pdb:6XEC|rcsb pdb:7KBG|rcsb pdb:7KBH|rcsb pdb:7LTG|rcsb pdb:7LTK|rcsb pdb:7LTL|reactome:R-HSA-193670|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9615017|reactome:R-HSA-9619665|reactome:R-HSA-9679191|reactome:R-HSA-983231|rcsb pdb:6WBZ|refseq:NP_001518.3|dip:DIP-24220N|refseq:XP_011534090.1|refseq:XP_016866288.1|uniprotkb:Q92769(identity)|entrezgene/locuslink:3066(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:K4PpGz9E9/TrQZsgvrJuc+uYCn89606 intact-crc:0D2D2E859ED6DF53|rigid:ZvH96NCJKngCKNf8HtQujsD1ths false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q8NHM5 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-3955564|uniprotkb:Q1RLM7|uniprotkb:Q8NCI2|uniprotkb:Q96HC7|uniprotkb:Q96SL0|uniprotkb:Q96T03|uniprotkb:Q9NS96|uniprotkb:Q9UF75|ensembl:ENSP00000366271|uniprotkb:A8MRS1 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:kdm2b_human(display_long)|uniprotkb:KDM2B(gene name)|psi-mi:KDM2B(display_short)|uniprotkb:CXXC2(gene name synonym)|uniprotkb:FBL10(gene name synonym)|uniprotkb:FBXL10(gene name synonym)|uniprotkb:JHDM1B(gene name synonym)|uniprotkb:PCCX2(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 2(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 10(gene name synonym)|uniprotkb:F-box protein FBL10(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 10(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1B(gene name synonym)|uniprotkb:Jumonji domain-containing EMSY-interactor methyltransferase motif protein(gene name synonym)|uniprotkb:Protein-containing CXXC domain 2(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1B(gene name synonym)|uniprotkb:NDY1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835180|imex:IM-21659-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity)|ddbj/embl/genbank:BC002922(identity) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENST00000377071(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0021555"(midbrain-hindbrain boundary morphogenesis)|go:"GO:0021592"(fourth ventricle development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021678"(third ventricle development)|go:"GO:0021993"(initiation of neural tube closure)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|interpro:IPR041070|interpro:IPR041667|mint:Q8NHM5|rcsb pdb:4O64|rcsb pdb:5JH5|rcsb pdb:6BVA|reactome:R-HSA-3214842|refseq:NP_115979.3|ensembl:ENSG00000089094(gene)|refseq:NP_001005366.1|uniprotkb:Q8NHM5(identity)|entrezgene/locuslink:84678(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:tnMbfP2oxwaaDyHHAigNt5hx4hM9606 intact-crc:780ADC709D2F3E7F|rigid:CwPypehGuAacRdXKNz+wzYvDNCI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:O95503 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-3951758|uniprotkb:A8KAH0|uniprotkb:Q96EM5|intact:EBI-28986885|ensembl:ENSP00000384490 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:cbx6_human(display_long)|uniprotkb:CBX6(gene name)|psi-mi:CBX6(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835180|imex:IM-21659-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity)|ddbj/embl/genbank:BC002922(identity) refseq:NP_001290423.1|ensembl:ENSG00000183741(gene)|refseq:NP_055107.3|ensembl:ENST00000407418(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:O95503|rcsb pdb:3GV6|rcsb pdb:3I90|reactome:R-HSA-2559580|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSP00000384490|dip:DIP-48605N|uniprotkb:O95503(identity)|entrezgene/locuslink:23466(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:4iNHCYe1bjb/JcurXP1iGoO/2uA9606 intact-crc:780ADC709D2F3E7F|rigid:CwPypehGuAacRdXKNz+wzYvDNCI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q9HC52 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835180|imex:IM-21659-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity)|ddbj/embl/genbank:BC002922(identity) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N|uniprotkb:Q9HC52(identity)|entrezgene/locuslink:57332(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 intact-crc:780ADC709D2F3E7F|rigid:CwPypehGuAacRdXKNz+wzYvDNCI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:O95931 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-3923843|uniprotkb:Q86T17|ensembl:ENSP00000216133 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:cbx7_human(display_long)|uniprotkb:CBX7(gene name)|psi-mi:CBX7(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835180|imex:IM-21659-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity)|ddbj/embl/genbank:BC002922(identity) refseq:NP_783640.1|ensembl:ENSG00000100307(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|mint:O95931|rcsb pdb:2K1B|rcsb pdb:2L12|rcsb pdb:2L1B|rcsb pdb:3GS2|rcsb pdb:4MN3|rcsb pdb:5EPJ|rcsb pdb:6V2R|ensembl:ENST00000216133(transcript)|dip:DIP-44565N|uniprotkb:O95931(identity)|entrezgene/locuslink:23492(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:LDXV9srMj1BL2CaSSot1Bn0/EW49606 intact-crc:780ADC709D2F3E7F|rigid:CwPypehGuAacRdXKNz+wzYvDNCI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:P61244 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835180|imex:IM-21659-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity)|ddbj/embl/genbank:BC002922(identity) refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750|uniprotkb:P61244(identity)|entrezgene/locuslink:4149(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:I5d1d/zT353OsLios95yEITNoWU9606 intact-crc:780ADC709D2F3E7F|rigid:CwPypehGuAacRdXKNz+wzYvDNCI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q8NDX5 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-1223801|uniprotkb:Q5HYF0|uniprotkb:Q6NSG2|uniprotkb:Q8NFT7|uniprotkb:Q8NFZ1|uniprotkb:Q8TBM2|uniprotkb:Q9H971|uniprotkb:Q9H9I4|uniprotkb:A2RRP9|ensembl:ENSP00000420271 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:phc3_human(display_long)|uniprotkb:PHC3(gene name)|psi-mi:PHC3(display_short)|uniprotkb:EDR3(gene name synonym)|uniprotkb:PH3(gene name synonym)|uniprotkb:Homolog of polyhomeotic 3(gene name synonym)|uniprotkb:Early development regulatory protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835180|imex:IM-21659-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity)|ddbj/embl/genbank:BC002922(identity) refseq:NP_079223.3|refseq:NP_001295045.1|ensembl:ENSP00000420271|ensembl:ENST00000495893|ensembl:ENSP00000420294|ensembl:ENST00000497658|ensembl:ENSP00000420454|ensembl:ENSG00000173889(gene)|ensembl:ENST00000494943(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:Q8NDX5|rcsb pdb:4PZN|rcsb pdb:4PZO|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q8NDX5(identity)|entrezgene/locuslink:80012(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:hB1EMs+lCv19uuJ1O7+QiVCUoo89606 intact-crc:780ADC709D2F3E7F|rigid:CwPypehGuAacRdXKNz+wzYvDNCI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q14781 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-745934|uniprotkb:Q9BTB1|uniprotkb:Q0VDA5|ensembl:ENSP00000308750 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:cbx2_human(display_long)|uniprotkb:CBX2(gene name)|psi-mi:CBX2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835180|imex:IM-21659-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity)|ddbj/embl/genbank:BC002922(identity) refseq:NP_005180.1|refseq:NP_116036.1|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|go:"GO:0045137"(development of primary sexual characteristics)|interpro:IPR042796|mint:Q14781|rcsb pdb:2D9U|rcsb pdb:3H91|rcsb pdb:5EPK|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSG00000173894(gene)|ensembl:ENST00000310942(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|dip:DIP-48604N|uniprotkb:Q14781(identity)|entrezgene/locuslink:84733(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:220eC8UGlmAHHP2WAhZdAveHC3s9606 intact-crc:780ADC709D2F3E7F|rigid:CwPypehGuAacRdXKNz+wzYvDNCI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q9BYE7 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835180|imex:IM-21659-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity)|ddbj/embl/genbank:BC002922(identity) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 intact-crc:780ADC709D2F3E7F|rigid:CwPypehGuAacRdXKNz+wzYvDNCI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q9ULD2 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-2818124|uniprotkb:A8K135|uniprotkb:Q9H7T2|uniprotkb:Q6PK49|uniprotkb:Q659F4|uniprotkb:B3KWJ9|uniprotkb:B9EGA1|uniprotkb:Q63HJ6|uniprotkb:Q8WTT9|uniprotkb:Q8N4M6|uniprotkb:Q6URW7|uniprotkb:B2RBJ6|uniprotkb:D3DSP8|uniprotkb:B4DH03|ensembl:ENSP00000262102 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:mtus1_human(display_long)|uniprotkb:MTUS1(gene name)|psi-mi:MTUS1(display_short)|uniprotkb:ATBP(gene name synonym)|uniprotkb:ATIP(gene name synonym)|uniprotkb:GK1(gene name synonym)|uniprotkb:KIAA1288(gene name synonym)|uniprotkb:MTSG1(gene name synonym)|uniprotkb:AT2 receptor-binding protein(gene name synonym)|uniprotkb:Angiotensin-II type 2 receptor-interacting protein(gene name synonym)|uniprotkb:Mitochondrial tumor suppressor 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835180|imex:IM-21659-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity)|ddbj/embl/genbank:BC002922(identity) refseq:NP_001001924.1|refseq:NP_001001925.1|refseq:NP_001001931.1|refseq:NP_001159865.1|refseq:NP_065800.1|refseq:NP_001317399.1|refseq:XP_016869189.1|refseq:XP_016869190.1|refseq:XP_016869191.1|ensembl:ENSG00000129422(gene)|ensembl:ENST00000262102(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008017"(microtubule binding)|go:"GO:0010758"(regulation of macrophage chemotaxis)|go:"GO:0015630"(microtubule cytoskeleton)|interpro:IPR029786|refseq:XP_005273636.1|refseq:XP_005273639.1|uniprotkb:Q9ULD2(identity)|entrezgene/locuslink:57509(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:48081802hEyRtGe+P2jOMZG0QWs9606 intact-crc:780ADC709D2F3E7F|rigid:CwPypehGuAacRdXKNz+wzYvDNCI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q8IWI9 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-2815196|uniprotkb:E7ENI0|uniprotkb:F5H7K2|uniprotkb:Q9H9N7|uniprotkb:Q9H8R3|uniprotkb:Q9Y4E9|uniprotkb:Q9UG69|intact:EBI-11143500|intact:EBI-10969960|ensembl:ENSP00000219905|uniprotkb:B9EGR5 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:mgap_human(display_long)|uniprotkb:MGA(gene name)|psi-mi:MGA(display_short)|uniprotkb:KIAA0518(gene name synonym)|uniprotkb:MAD5(gene name synonym)|uniprotkb:MAX dimerization protein 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835180|imex:IM-21659-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity)|ddbj/embl/genbank:BC002922(identity) refseq:NP_001074010.2|ensembl:ENSP00000219905|ensembl:ENST00000566586|ensembl:ENSP00000456141|ensembl:ENSG00000174197(gene)|ensembl:ENST00000219905(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR018186|interpro:IPR032060|interpro:IPR036638|interpro:IPR036960|interpro:IPR037935|mint:Q8IWI9|reactome:R-HSA-8953750|refseq:NP_001157745.1|dip:DIP-57615N|uniprotkb:Q8IWI9(identity)|entrezgene/locuslink:23269(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:P4lo9EteCvikQQk5kyVkcobitLU9606 intact-crc:780ADC709D2F3E7F|rigid:CwPypehGuAacRdXKNz+wzYvDNCI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:P61962 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835180|imex:IM-21659-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity)|ddbj/embl/genbank:BC002922(identity) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 intact-crc:780ADC709D2F3E7F|rigid:CwPypehGuAacRdXKNz+wzYvDNCI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q3KNV8 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-2339807|uniprotkb:O15262|uniprotkb:D3DVN1|ensembl:ENSP00000354724|ensembl:ENSP00000420489 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:pcgf3_human(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835180|imex:IM-21659-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity)|ddbj/embl/genbank:BC002922(identity) refseq:NP_006306.2|refseq:NP_001304765.1|dip:DIP-52782N|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q3KNV8|uniprotkb:Q3KNV8(identity)|entrezgene/locuslink:10336(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606 intact-crc:780ADC709D2F3E7F|rigid:CwPypehGuAacRdXKNz+wzYvDNCI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q8N488 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835180|imex:IM-21659-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity)|ddbj/embl/genbank:BC002922(identity) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|uniprotkb:Q8N488(identity)|entrezgene/locuslink:23429(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 intact-crc:780ADC709D2F3E7F|rigid:CwPypehGuAacRdXKNz+wzYvDNCI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:P19784 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-347451|ensembl:ENSP00000262506 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835180|imex:IM-21659-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity)|ddbj/embl/genbank:BC002922(identity) refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|uniprotkb:P19784(identity)|entrezgene/locuslink:1459(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 intact-crc:780ADC709D2F3E7F|rigid:CwPypehGuAacRdXKNz+wzYvDNCI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q8WXX7 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-2875359|ensembl:ENSP00000344087|uniprotkb:L7QET3|uniprotkb:L7QF75|uniprotkb:Q5D049|uniprotkb:Q9Y4F2|uniprotkb:A4D1Y9|uniprotkb:Q6PJU5 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:auts2_human(display_long)|uniprotkb:AUTS2(gene name)|psi-mi:AUTS2(display_short)|uniprotkb:KIAA0442(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835180|imex:IM-21659-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity)|ddbj/embl/genbank:BC002922(identity) ensembl:ENSG00000158321(gene)|ensembl:ENST00000342771(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048675"(axon extension)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0097484"(dendrite extension)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR023246|reactome:R-HSA-8939243|refseq:NP_001120703.1|refseq:NP_001120704.1|refseq:NP_056385.1|dip:DIP-61355N|uniprotkb:Q8WXX7(identity)|entrezgene/locuslink:26053(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:8m3VWlXEISEyVwNmlwDFEEKl4Sg9606 intact-crc:780ADC709D2F3E7F|rigid:CwPypehGuAacRdXKNz+wzYvDNCI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:P61964 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835180|imex:IM-21659-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity)|ddbj/embl/genbank:BC002922(identity) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|entrezgene/locuslink:11091(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 intact-crc:780ADC709D2F3E7F|rigid:CwPypehGuAacRdXKNz+wzYvDNCI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q5H9F3 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-8833946|uniprotkb:Q5H9F4|uniprotkb:Q9Y528|uniprotkb:Q8TEN3|uniprotkb:B5MDQ8|uniprotkb:Q6ZVE0|uniprotkb:Q5H9F2|ensembl:ENSP00000218147|ensembl:ENSP00000437775 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:bcorl_human(display_long)|uniprotkb:BCORL1(gene name)|psi-mi:BCORL1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835180|imex:IM-21659-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity)|ddbj/embl/genbank:BC002922(identity) ensembl:ENSP00000218147|ensembl:ENSP00000437775|refseq:NP_068765.3|dip:DIP-60148N|ensembl:ENSG00000085185(gene)|ensembl:ENST00000218147(transcript)|ensembl:ENST00000540052(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q5H9F3|rcsb pdb:4HPM|rcsb pdb:5JH5|uniprotkb:Q5H9F3(identity)|entrezgene/locuslink:63035(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:uQdpjjO3QnnX19nR1Ky76HjCdhw9606 intact-crc:780ADC709D2F3E7F|rigid:CwPypehGuAacRdXKNz+wzYvDNCI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:P67870 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-348169|ensembl:ENSP00000365025|ensembl:ENSP00000365026|ensembl:ENSP00000365042|ensembl:ENSP00000372919|ensembl:ENSP00000372925|ensembl:ENSP00000382980|ensembl:ENSP00000390900|ensembl:ENSP00000391038|ensembl:ENSP00000393756|ensembl:ENSP00000394855|ensembl:ENSP00000395275|ensembl:ENSP00000400188|ensembl:ENSP00000407018|ensembl:ENSP00000407379|ensembl:ENSP00000409510|ensembl:ENSP00000410802|ensembl:ENSP00000411322|ensembl:ENSP00000412520|ensembl:ENSP00000413469|ensembl:ENSP00000415237|ensembl:ENSP00000415303|uniprotkb:P07312|uniprotkb:P13862|uniprotkb:Q4VX47|intact:EBI-3866975|uniprotkb:B0UXA9 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:csk2b_human(display_long)|uniprotkb:Phosvitin(gene name synonym)|uniprotkb:Protein G5a(gene name synonym)|uniprotkb:CSNK2B(gene name)|psi-mi:CSNK2B(display_short)|uniprotkb:CK2N(gene name synonym)|uniprotkb:G5A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835180|imex:IM-21659-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity)|ddbj/embl/genbank:BC002922(identity) ensembl:ENSG00000204435(gene)|ensembl:ENSG00000230700(gene)|ensembl:ENSG00000206406(gene)|ensembl:ENSG00000232960(gene)|ensembl:ENSG00000224398(gene)|ensembl:ENSG00000224774(gene)|ensembl:ENSG00000228875(gene)|ensembl:ENST00000375882(transcript)|ensembl:ENST00000383427(transcript)|ensembl:ENST00000383433(transcript)|ensembl:ENST00000400110(transcript)|ensembl:ENST00000412802(transcript)|ensembl:ENST00000418230(transcript)|ensembl:ENST00000422567(transcript)|ensembl:ENST00000429633(transcript)|ensembl:ENST00000431476(transcript)|ensembl:ENST00000436169(transcript)|ensembl:ENST00000443673(transcript)|ensembl:ENST00000448596(transcript)|ensembl:ENST00000451917(transcript)|ensembl:ENST00000452985(transcript)|ensembl:ENST00000453234(transcript)|ensembl:ENST00000454382(transcript)|ensembl:ENST00000454511(transcript)|ensembl:ENST00000455161(transcript)|ensembl:ENST00000458330(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0007165"(signal transduction)|ensembl:ENST00000375865(transcript)|ensembl:ENST00000375866(transcript)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016363"(nuclear matrix)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0034622"|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|mint:P67870|rcsb pdb:1DS5|rcsb pdb:1JWH|go:"GO:0008134"(transcription factor binding)|rcsb pdb:1QF8|rcsb pdb:3EED|rcsb pdb:4DGL|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6798695|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:6Q38|refseq:NP_001311.3|refseq:NP_001269314.1|dip:DIP-131N|uniprotkb:P67870(identity)|entrezgene/locuslink:1460(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:ZTHJjCqHg2dE7B+WoSU28VSMuPg9606 intact-crc:780ADC709D2F3E7F|rigid:CwPypehGuAacRdXKNz+wzYvDNCI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q9HAH7 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-2847800|uniprotkb:Q9H9X4|uniprotkb:Q96CI9|uniprotkb:B4DP86|ensembl:ENSP00000287468 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:fbrs_human(display_long)|uniprotkb:FBRS(gene name)|psi-mi:FBRS(display_short)|uniprotkb:FBS(gene name synonym)|uniprotkb:FBS1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835180|imex:IM-21659-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity)|ddbj/embl/genbank:BC002922(identity) refseq:NP_001098549.2|dip:DIP-61357N|ensembl:ENSG00000156860(gene)|ensembl:ENST00000287468(transcript)|interpro:IPR023246|mint:Q9HAH7|uniprotkb:Q9HAH7(identity)|entrezgene/locuslink:64319(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:n1zkWAYdgwY+t7CFWg5RKO1VSfE9606 intact-crc:780ADC709D2F3E7F|rigid:CwPypehGuAacRdXKNz+wzYvDNCI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:P78364 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-725403|uniprotkb:Q8WVM3|uniprotkb:Q9BU63|uniprotkb:D3DUV4|ensembl:ENSP00000437659|ensembl:ENSP00000440674 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:phc1_human(display_long)|uniprotkb:Early development regulatory protein 1(gene name synonym)|uniprotkb:PHC1(gene name)|psi-mi:PHC1(display_short)|uniprotkb:EDR1(gene name synonym)|uniprotkb:PH1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835180|imex:IM-21659-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity)|ddbj/embl/genbank:BC002922(identity) refseq:NP_004417.2|ensembl:ENSG00000111752(gene)|ensembl:ENST00000543824(transcript)|ensembl:ENST00000544916(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:P78364|rcsb pdb:2L8E|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|dip:DIP-44567N|uniprotkb:P78364(identity)|entrezgene/locuslink:1911(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:0dDjrgvWcP5Sx8h+qUj7awuM3ko9606 intact-crc:780ADC709D2F3E7F|rigid:CwPypehGuAacRdXKNz+wzYvDNCI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q6W2J9 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835180|imex:IM-21659-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity)|ddbj/embl/genbank:BC002922(identity) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N|uniprotkb:Q6W2J9(identity)|entrezgene/locuslink:54880(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 intact-crc:780ADC709D2F3E7F|rigid:CwPypehGuAacRdXKNz+wzYvDNCI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:O00257 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835180|imex:IM-21659-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity)|ddbj/embl/genbank:BC002922(identity) refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|uniprotkb:O00257(identity)|entrezgene/locuslink:8535(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 intact-crc:780ADC709D2F3E7F|rigid:CwPypehGuAacRdXKNz+wzYvDNCI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:P68400 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835180|imex:IM-21659-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity)|ddbj/embl/genbank:BC002922(identity) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N|uniprotkb:P68400(identity)|entrezgene/locuslink:1457(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 intact-crc:780ADC709D2F3E7F|rigid:CwPypehGuAacRdXKNz+wzYvDNCI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:P63208 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835180|imex:IM-21659-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity)|ddbj/embl/genbank:BC002922(identity) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|entrezgene/locuslink:6500(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 intact-crc:780ADC709D2F3E7F|rigid:CwPypehGuAacRdXKNz+wzYvDNCI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q13185 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835180|imex:IM-21659-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity)|ddbj/embl/genbank:BC002922(identity) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 intact-crc:780ADC709D2F3E7F|rigid:CwPypehGuAacRdXKNz+wzYvDNCI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q969R5 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835180|imex:IM-21659-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity)|ddbj/embl/genbank:BC002922(identity) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750|uniprotkb:Q969R5(identity)|entrezgene/locuslink:83746(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 intact-crc:780ADC709D2F3E7F|rigid:CwPypehGuAacRdXKNz+wzYvDNCI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q8IY57 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835180|imex:IM-21659-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity)|ddbj/embl/genbank:BC002922(identity) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|entrezgene/locuslink:10138(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 intact-crc:780ADC709D2F3E7F|rigid:CwPypehGuAacRdXKNz+wzYvDNCI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:P35227 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-2129767|uniprotkb:A6NGD8|ensembl:ENSP00000478517|ensembl:ENSP00000478970|ensembl:ENSP00000482063|ensembl:ENSP00000482815|ensembl:ENSP00000488868|ensembl:ENSP00000488872 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:pcgf2_human(display_long)|uniprotkb:PCGF2(gene name)|psi-mi:PCGF2(display_short)|uniprotkb:MEL18(gene name synonym)|uniprotkb:RNF110(gene name synonym)|uniprotkb:ZNF144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835180|imex:IM-21659-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity)|ddbj/embl/genbank:BC002922(identity) refseq:NP_009075.1|refseq:XP_016880505.1|refseq:XP_005257697.1|refseq:XP_005257698.1|refseq:XP_005257699.1|dip:DIP-41880N|ensembl:ENSG00000277258(gene)|ensembl:ENSG00000278644(gene)|ensembl:ENST00000610440(transcript)|ensembl:ENST00000611883(transcript)|ensembl:ENST00000616199(transcript)|ensembl:ENST00000620225(transcript)|ensembl:ENST00000631566(transcript)|ensembl:ENST00000631610(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35227|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-5617472|reactome:R-HSA-8953750|uniprotkb:P35227(identity)|entrezgene/locuslink:7703(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:zppw56VrEl6gEFwtJMCN5cQkPxI9606 intact-crc:780ADC709D2F3E7F|rigid:CwPypehGuAacRdXKNz+wzYvDNCI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q01094 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-448924|uniprotkb:Q13143|uniprotkb:Q92768|ensembl:ENSP00000345571 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:e2f1_human(display_long)|uniprotkb:Retinoblastoma-associated protein 1(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 3(gene name synonym)|uniprotkb:PBR3(gene name synonym)|uniprotkb:E2F1(gene name)|psi-mi:E2F1(display_short)|uniprotkb:RBBP3(gene name synonym)|uniprotkb:pRB-binding protein E2F-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835180|imex:IM-21659-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity)|ddbj/embl/genbank:BC002922(identity) refseq:NP_005216.1|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071930"(negative regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990086"(lens fiber cell apoptotic process)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030900"(forebrain development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043276"(anoikis)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048255"(mRNA stabilization)|ensembl:ENSG00000101412(gene)|ensembl:ENST00000343380(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804116|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:Q01094|rcsb pdb:1H24|rcsb pdb:1O9K|rcsb pdb:2AZE|rcsb pdb:5M9N|rcsb pdb:5M9O|rcsb pdb:6G0P|rcsb pdb:6ULS|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1912408|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9616222|reactome:R-HSA-9661069|dip:DIP-24227N|uniprotkb:Q01094(identity)|entrezgene/locuslink:1869(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:vPNenpmxyXpHjMzUID54cwMFk+Y9606 intact-crc:780ADC709D2F3E7F|rigid:CwPypehGuAacRdXKNz+wzYvDNCI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q9BSM1 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835180|imex:IM-21659-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity)|ddbj/embl/genbank:BC002922(identity) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5|uniprotkb:Q9BSM1(identity)|entrezgene/locuslink:84759(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 intact-crc:780ADC709D2F3E7F|rigid:CwPypehGuAacRdXKNz+wzYvDNCI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q8NEZ4 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-1042997|uniprotkb:Q8NC02|uniprotkb:Q8NDF6|uniprotkb:Q9H9P4|uniprotkb:Q9NR13|uniprotkb:Q9P222|uniprotkb:Q9UDR7|ensembl:ENSP00000262189 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:kmt2c_human(display_long)|uniprotkb:KMT2C(gene name)|psi-mi:KMT2C(display_short)|uniprotkb:HALR(gene name synonym)|uniprotkb:Homologous to ALR protein(gene name synonym)|uniprotkb:KIAA1506(gene name synonym)|uniprotkb:MLL3(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835180|imex:IM-21659-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity)|ddbj/embl/genbank:BC002922(identity) ensembl:ENSG00000055609(gene)|ensembl:ENST00000262189(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR000637(HMG-I and HMG-Y, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|go:"GO:0005634"(nucleus)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036910|interpro:IPR037877|interpro:IPR041967|interpro:IPR041968|mint:Q8NEZ4|rcsb pdb:2YSM|rcsb pdb:2YUK|rcsb pdb:3UVL|rcsb pdb:4ERY|rcsb pdb:5F59|rcsb pdb:5F6K|rcsb pdb:6KIW|rcsb pdb:6MLC|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8936459|refseq:NP_733751.2|ensembl:ENSP00000262189|ensembl:ENST00000682283|ensembl:ENSP00000507485|dip:DIP-48649N|uniprotkb:Q8NEZ4(identity)|entrezgene/locuslink:58508(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:NZg8HgfbohMT8EEgAdAgWR1AjSo9606 intact-crc:780ADC709D2F3E7F|rigid:CwPypehGuAacRdXKNz+wzYvDNCI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q9HCM7 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-6255777|ensembl:ENSP00000396160|uniprotkb:Q86XQ1 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:fbsl_human(display_long)|uniprotkb:FBRSL1(gene name)|psi-mi:FBRSL1(display_short)|uniprotkb:AUTS2L(gene name synonym)|uniprotkb:KIAA1545(gene name synonym)|uniprotkb:XTP9(gene name synonym)|uniprotkb:AUTS2-like protein(gene name synonym)|uniprotkb:HBV X-transactivated gene 9 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835180|imex:IM-21659-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity)|ddbj/embl/genbank:BC002922(identity) ensembl:ENSG00000112787(gene)|ensembl:ENST00000434748(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR023246|refseq:NP_001136113.1|uniprotkb:Q9HCM7(identity)|entrezgene/locuslink:57666(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:JstP98Bp/L0+GmkLfSdhDHnWmiU9606 intact-crc:780ADC709D2F3E7F|rigid:CwPypehGuAacRdXKNz+wzYvDNCI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q86SE9 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835180|imex:IM-21659-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity)|ddbj/embl/genbank:BC002922(identity) refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N|uniprotkb:Q86SE9(identity)|entrezgene/locuslink:84333(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606 intact-crc:780ADC709D2F3E7F|rigid:CwPypehGuAacRdXKNz+wzYvDNCI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:P35226 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835180|imex:IM-21659-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity)|ddbj/embl/genbank:BC002922(identity) refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:P35226(identity)|entrezgene/locuslink:100532731(identity)|entrezgene/locuslink:648(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606 intact-crc:780ADC709D2F3E7F|rigid:CwPypehGuAacRdXKNz+wzYvDNCI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:O75461 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835180|imex:IM-21659-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity)|ddbj/embl/genbank:BC002922(identity) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 intact-crc:780ADC709D2F3E7F|rigid:CwPypehGuAacRdXKNz+wzYvDNCI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q8IXK0 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-713786|uniprotkb:Q8N306|uniprotkb:Q8TAG8|uniprotkb:A1L4Q1|uniprotkb:Q2TAL3|uniprotkb:Q5T0C1|uniprotkb:Q6NUJ6|uniprotkb:Q6ZQR1|uniprotkb:Q96BL4|uniprotkb:Q9Y4Y7|ensembl:ENSP00000257118|uniprotkb:D3DPR2|uniprotkb:A8KA40 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:phc2_human(display_long)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:PHC2(gene name)|psi-mi:PHC2(display_short)|uniprotkb:EDR2(gene name synonym)|uniprotkb:PH2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835180|imex:IM-21659-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity)|ddbj/embl/genbank:BC002922(identity) interpro:IPR038603|mint:Q8IXK0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR013761(Sterile alpha motif-type)|ensembl:ENSG00000134686(gene)|ensembl:ENST00000257118(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|refseq:NP_004418.2|refseq:NP_932157.1|refseq:XP_016856005.1|refseq:XP_016856006.1|refseq:XP_016856007.1|refseq:XP_005270627.1|dip:DIP-34464N|uniprotkb:Q8IXK0(identity)|entrezgene/locuslink:1912(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:7si/KU2tHoxviuCr70ncQERDWmY9606 intact-crc:780ADC709D2F3E7F|rigid:CwPypehGuAacRdXKNz+wzYvDNCI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q14186 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835180|imex:IM-21659-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity)|ddbj/embl/genbank:BC002922(identity) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|entrezgene/locuslink:7027(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 intact-crc:780ADC709D2F3E7F|rigid:CwPypehGuAacRdXKNz+wzYvDNCI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:Q8NHM5 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-3955564|uniprotkb:Q1RLM7|uniprotkb:Q8NCI2|uniprotkb:Q96HC7|uniprotkb:Q96SL0|uniprotkb:Q96T03|uniprotkb:Q9NS96|uniprotkb:Q9UF75|ensembl:ENSP00000366271|uniprotkb:A8MRS1 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:kdm2b_human(display_long)|uniprotkb:KDM2B(gene name)|psi-mi:KDM2B(display_short)|uniprotkb:CXXC2(gene name synonym)|uniprotkb:FBL10(gene name synonym)|uniprotkb:FBXL10(gene name synonym)|uniprotkb:JHDM1B(gene name synonym)|uniprotkb:PCCX2(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 2(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 10(gene name synonym)|uniprotkb:F-box protein FBL10(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 10(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1B(gene name synonym)|uniprotkb:Jumonji domain-containing EMSY-interactor methyltransferase motif protein(gene name synonym)|uniprotkb:Protein-containing CXXC domain 2(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1B(gene name synonym)|uniprotkb:NDY1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835339|imex:IM-21659-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|ddbj/embl/genbank:BC012583(identity)|entrezgene/locuslink:6045(identity) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENST00000377071(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0021555"(midbrain-hindbrain boundary morphogenesis)|go:"GO:0021592"(fourth ventricle development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021678"(third ventricle development)|go:"GO:0021993"(initiation of neural tube closure)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|interpro:IPR041070|interpro:IPR041667|mint:Q8NHM5|rcsb pdb:4O64|rcsb pdb:5JH5|rcsb pdb:6BVA|reactome:R-HSA-3214842|refseq:NP_115979.3|ensembl:ENSG00000089094(gene)|refseq:NP_001005366.1|uniprotkb:Q8NHM5(identity)|entrezgene/locuslink:84678(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:tnMbfP2oxwaaDyHHAigNt5hx4hM9606 intact-crc:567ED2CE549F4AF2|rigid:hlWa8DjDEoAbPq9IyGU2rgsSccY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:O95503 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-3951758|uniprotkb:A8KAH0|uniprotkb:Q96EM5|intact:EBI-28986885|ensembl:ENSP00000384490 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:cbx6_human(display_long)|uniprotkb:CBX6(gene name)|psi-mi:CBX6(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835339|imex:IM-21659-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|ddbj/embl/genbank:BC012583(identity)|entrezgene/locuslink:6045(identity) refseq:NP_001290423.1|ensembl:ENSG00000183741(gene)|refseq:NP_055107.3|ensembl:ENST00000407418(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:O95503|rcsb pdb:3GV6|rcsb pdb:3I90|reactome:R-HSA-2559580|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSP00000384490|dip:DIP-48605N|uniprotkb:O95503(identity)|entrezgene/locuslink:23466(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:4iNHCYe1bjb/JcurXP1iGoO/2uA9606 intact-crc:567ED2CE549F4AF2|rigid:hlWa8DjDEoAbPq9IyGU2rgsSccY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:Q14186 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835339|imex:IM-21659-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|ddbj/embl/genbank:BC012583(identity)|entrezgene/locuslink:6045(identity) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|entrezgene/locuslink:7027(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 intact-crc:567ED2CE549F4AF2|rigid:hlWa8DjDEoAbPq9IyGU2rgsSccY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:Q8IWI9 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-2815196|uniprotkb:E7ENI0|uniprotkb:F5H7K2|uniprotkb:Q9H9N7|uniprotkb:Q9H8R3|uniprotkb:Q9Y4E9|uniprotkb:Q9UG69|intact:EBI-11143500|intact:EBI-10969960|ensembl:ENSP00000219905|uniprotkb:B9EGR5 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:mgap_human(display_long)|uniprotkb:MGA(gene name)|psi-mi:MGA(display_short)|uniprotkb:KIAA0518(gene name synonym)|uniprotkb:MAD5(gene name synonym)|uniprotkb:MAX dimerization protein 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835339|imex:IM-21659-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|ddbj/embl/genbank:BC012583(identity)|entrezgene/locuslink:6045(identity) refseq:NP_001074010.2|ensembl:ENSP00000219905|ensembl:ENST00000566586|ensembl:ENSP00000456141|ensembl:ENSG00000174197(gene)|ensembl:ENST00000219905(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR018186|interpro:IPR032060|interpro:IPR036638|interpro:IPR036960|interpro:IPR037935|mint:Q8IWI9|reactome:R-HSA-8953750|refseq:NP_001157745.1|dip:DIP-57615N|uniprotkb:Q8IWI9(identity)|entrezgene/locuslink:23269(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:P4lo9EteCvikQQk5kyVkcobitLU9606 intact-crc:567ED2CE549F4AF2|rigid:hlWa8DjDEoAbPq9IyGU2rgsSccY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:Q8NDX5 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-1223801|uniprotkb:Q5HYF0|uniprotkb:Q6NSG2|uniprotkb:Q8NFT7|uniprotkb:Q8NFZ1|uniprotkb:Q8TBM2|uniprotkb:Q9H971|uniprotkb:Q9H9I4|uniprotkb:A2RRP9|ensembl:ENSP00000420271 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:phc3_human(display_long)|uniprotkb:PHC3(gene name)|psi-mi:PHC3(display_short)|uniprotkb:EDR3(gene name synonym)|uniprotkb:PH3(gene name synonym)|uniprotkb:Homolog of polyhomeotic 3(gene name synonym)|uniprotkb:Early development regulatory protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835339|imex:IM-21659-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|ddbj/embl/genbank:BC012583(identity)|entrezgene/locuslink:6045(identity) refseq:NP_079223.3|refseq:NP_001295045.1|ensembl:ENSP00000420271|ensembl:ENST00000495893|ensembl:ENSP00000420294|ensembl:ENST00000497658|ensembl:ENSP00000420454|ensembl:ENSG00000173889(gene)|ensembl:ENST00000494943(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:Q8NDX5|rcsb pdb:4PZN|rcsb pdb:4PZO|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q8NDX5(identity)|entrezgene/locuslink:80012(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:hB1EMs+lCv19uuJ1O7+QiVCUoo89606 intact-crc:567ED2CE549F4AF2|rigid:hlWa8DjDEoAbPq9IyGU2rgsSccY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:P68400 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835339|imex:IM-21659-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|ddbj/embl/genbank:BC012583(identity)|entrezgene/locuslink:6045(identity) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N|uniprotkb:P68400(identity)|entrezgene/locuslink:1457(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 intact-crc:567ED2CE549F4AF2|rigid:hlWa8DjDEoAbPq9IyGU2rgsSccY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:Q9HAH7 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-2847800|uniprotkb:Q9H9X4|uniprotkb:Q96CI9|uniprotkb:B4DP86|ensembl:ENSP00000287468 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:fbrs_human(display_long)|uniprotkb:FBRS(gene name)|psi-mi:FBRS(display_short)|uniprotkb:FBS(gene name synonym)|uniprotkb:FBS1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835339|imex:IM-21659-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|ddbj/embl/genbank:BC012583(identity)|entrezgene/locuslink:6045(identity) refseq:NP_001098549.2|dip:DIP-61357N|ensembl:ENSG00000156860(gene)|ensembl:ENST00000287468(transcript)|interpro:IPR023246|mint:Q9HAH7|entrezgene/locuslink:64319(identity)|uniprotkb:Q9HAH7(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:n1zkWAYdgwY+t7CFWg5RKO1VSfE9606 intact-crc:567ED2CE549F4AF2|rigid:hlWa8DjDEoAbPq9IyGU2rgsSccY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:Q14781 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-745934|uniprotkb:Q9BTB1|uniprotkb:Q0VDA5|ensembl:ENSP00000308750 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:cbx2_human(display_long)|uniprotkb:CBX2(gene name)|psi-mi:CBX2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835339|imex:IM-21659-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|ddbj/embl/genbank:BC012583(identity)|entrezgene/locuslink:6045(identity) refseq:NP_005180.1|refseq:NP_116036.1|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|go:"GO:0045137"(development of primary sexual characteristics)|interpro:IPR042796|mint:Q14781|rcsb pdb:2D9U|rcsb pdb:3H91|rcsb pdb:5EPK|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSG00000173894(gene)|ensembl:ENST00000310942(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|dip:DIP-48604N|uniprotkb:Q14781(identity)|entrezgene/locuslink:84733(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:220eC8UGlmAHHP2WAhZdAveHC3s9606 intact-crc:567ED2CE549F4AF2|rigid:hlWa8DjDEoAbPq9IyGU2rgsSccY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:Q9BYE7 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835339|imex:IM-21659-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|ddbj/embl/genbank:BC012583(identity)|entrezgene/locuslink:6045(identity) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 intact-crc:567ED2CE549F4AF2|rigid:hlWa8DjDEoAbPq9IyGU2rgsSccY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:P19784 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-347451|ensembl:ENSP00000262506 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835339|imex:IM-21659-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|ddbj/embl/genbank:BC012583(identity)|entrezgene/locuslink:6045(identity) refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|uniprotkb:P19784(identity)|entrezgene/locuslink:1459(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 intact-crc:567ED2CE549F4AF2|rigid:hlWa8DjDEoAbPq9IyGU2rgsSccY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:O95931 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-3923843|uniprotkb:Q86T17|ensembl:ENSP00000216133 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:cbx7_human(display_long)|uniprotkb:CBX7(gene name)|psi-mi:CBX7(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835339|imex:IM-21659-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|ddbj/embl/genbank:BC012583(identity)|entrezgene/locuslink:6045(identity) refseq:NP_783640.1|ensembl:ENSG00000100307(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|mint:O95931|rcsb pdb:2K1B|rcsb pdb:2L12|rcsb pdb:2L1B|rcsb pdb:3GS2|rcsb pdb:4MN3|rcsb pdb:5EPJ|rcsb pdb:6V2R|ensembl:ENST00000216133(transcript)|dip:DIP-44565N|uniprotkb:O95931(identity)|entrezgene/locuslink:23492(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:LDXV9srMj1BL2CaSSot1Bn0/EW49606 intact-crc:567ED2CE549F4AF2|rigid:hlWa8DjDEoAbPq9IyGU2rgsSccY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:Q13185 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835339|imex:IM-21659-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|ddbj/embl/genbank:BC012583(identity)|entrezgene/locuslink:6045(identity) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 intact-crc:567ED2CE549F4AF2|rigid:hlWa8DjDEoAbPq9IyGU2rgsSccY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:P35227 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-2129767|uniprotkb:A6NGD8|ensembl:ENSP00000478517|ensembl:ENSP00000478970|ensembl:ENSP00000482063|ensembl:ENSP00000482815|ensembl:ENSP00000488868|ensembl:ENSP00000488872 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:pcgf2_human(display_long)|uniprotkb:PCGF2(gene name)|psi-mi:PCGF2(display_short)|uniprotkb:MEL18(gene name synonym)|uniprotkb:RNF110(gene name synonym)|uniprotkb:ZNF144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835339|imex:IM-21659-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|ddbj/embl/genbank:BC012583(identity)|entrezgene/locuslink:6045(identity) refseq:NP_009075.1|refseq:XP_016880505.1|refseq:XP_005257697.1|refseq:XP_005257698.1|refseq:XP_005257699.1|dip:DIP-41880N|ensembl:ENSG00000277258(gene)|ensembl:ENSG00000278644(gene)|ensembl:ENST00000610440(transcript)|ensembl:ENST00000611883(transcript)|ensembl:ENST00000616199(transcript)|ensembl:ENST00000620225(transcript)|ensembl:ENST00000631566(transcript)|ensembl:ENST00000631610(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35227|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-5617472|reactome:R-HSA-8953750|uniprotkb:P35227(identity)|entrezgene/locuslink:7703(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:zppw56VrEl6gEFwtJMCN5cQkPxI9606 intact-crc:567ED2CE549F4AF2|rigid:hlWa8DjDEoAbPq9IyGU2rgsSccY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:Q9HCM7 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-6255777|ensembl:ENSP00000396160|uniprotkb:Q86XQ1 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:fbsl_human(display_long)|uniprotkb:FBRSL1(gene name)|psi-mi:FBRSL1(display_short)|uniprotkb:AUTS2L(gene name synonym)|uniprotkb:KIAA1545(gene name synonym)|uniprotkb:XTP9(gene name synonym)|uniprotkb:AUTS2-like protein(gene name synonym)|uniprotkb:HBV X-transactivated gene 9 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835339|imex:IM-21659-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|ddbj/embl/genbank:BC012583(identity)|entrezgene/locuslink:6045(identity) ensembl:ENSG00000112787(gene)|ensembl:ENST00000434748(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR023246|refseq:NP_001136113.1|uniprotkb:Q9HCM7(identity)|entrezgene/locuslink:57666(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:JstP98Bp/L0+GmkLfSdhDHnWmiU9606 intact-crc:567ED2CE549F4AF2|rigid:hlWa8DjDEoAbPq9IyGU2rgsSccY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:P35226 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835339|imex:IM-21659-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|ddbj/embl/genbank:BC012583(identity)|entrezgene/locuslink:6045(identity) refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:P35226(identity)|entrezgene/locuslink:100532731(identity)|entrezgene/locuslink:648(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606 intact-crc:567ED2CE549F4AF2|rigid:hlWa8DjDEoAbPq9IyGU2rgsSccY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:Q6W2J9 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835339|imex:IM-21659-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|ddbj/embl/genbank:BC012583(identity)|entrezgene/locuslink:6045(identity) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N|uniprotkb:Q6W2J9(identity)|entrezgene/locuslink:54880(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 intact-crc:567ED2CE549F4AF2|rigid:hlWa8DjDEoAbPq9IyGU2rgsSccY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:P63208 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835339|imex:IM-21659-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|ddbj/embl/genbank:BC012583(identity)|entrezgene/locuslink:6045(identity) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|entrezgene/locuslink:6500(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 intact-crc:567ED2CE549F4AF2|rigid:hlWa8DjDEoAbPq9IyGU2rgsSccY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:Q3KNV8 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-2339807|uniprotkb:O15262|uniprotkb:D3DVN1|ensembl:ENSP00000354724|ensembl:ENSP00000420489 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:pcgf3_human(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835339|imex:IM-21659-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|ddbj/embl/genbank:BC012583(identity)|entrezgene/locuslink:6045(identity) refseq:NP_006306.2|refseq:NP_001304765.1|dip:DIP-52782N|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q3KNV8|uniprotkb:Q3KNV8(identity)|entrezgene/locuslink:10336(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606 intact-crc:567ED2CE549F4AF2|rigid:hlWa8DjDEoAbPq9IyGU2rgsSccY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:Q8WXX7 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-2875359|ensembl:ENSP00000344087|uniprotkb:L7QET3|uniprotkb:L7QF75|uniprotkb:Q5D049|uniprotkb:Q9Y4F2|uniprotkb:A4D1Y9|uniprotkb:Q6PJU5 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:auts2_human(display_long)|uniprotkb:AUTS2(gene name)|psi-mi:AUTS2(display_short)|uniprotkb:KIAA0442(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835339|imex:IM-21659-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|ddbj/embl/genbank:BC012583(identity)|entrezgene/locuslink:6045(identity) ensembl:ENSG00000158321(gene)|ensembl:ENST00000342771(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048675"(axon extension)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0097484"(dendrite extension)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR023246|reactome:R-HSA-8939243|refseq:NP_001120703.1|refseq:NP_001120704.1|refseq:NP_056385.1|dip:DIP-61355N|uniprotkb:Q8WXX7(identity)|entrezgene/locuslink:26053(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:8m3VWlXEISEyVwNmlwDFEEKl4Sg9606 intact-crc:567ED2CE549F4AF2|rigid:hlWa8DjDEoAbPq9IyGU2rgsSccY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:Q9BSM1 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835339|imex:IM-21659-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|ddbj/embl/genbank:BC012583(identity)|entrezgene/locuslink:6045(identity) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5|uniprotkb:Q9BSM1(identity)|entrezgene/locuslink:84759(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 intact-crc:567ED2CE549F4AF2|rigid:hlWa8DjDEoAbPq9IyGU2rgsSccY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:Q969R5 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835339|imex:IM-21659-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|ddbj/embl/genbank:BC012583(identity)|entrezgene/locuslink:6045(identity) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750|uniprotkb:Q969R5(identity)|entrezgene/locuslink:83746(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 intact-crc:567ED2CE549F4AF2|rigid:hlWa8DjDEoAbPq9IyGU2rgsSccY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:P78364 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-725403|uniprotkb:Q8WVM3|uniprotkb:Q9BU63|uniprotkb:D3DUV4|ensembl:ENSP00000437659|ensembl:ENSP00000440674 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:phc1_human(display_long)|uniprotkb:Early development regulatory protein 1(gene name synonym)|uniprotkb:PHC1(gene name)|psi-mi:PHC1(display_short)|uniprotkb:EDR1(gene name synonym)|uniprotkb:PH1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835339|imex:IM-21659-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|ddbj/embl/genbank:BC012583(identity)|entrezgene/locuslink:6045(identity) refseq:NP_004417.2|ensembl:ENSG00000111752(gene)|ensembl:ENST00000543824(transcript)|ensembl:ENST00000544916(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:P78364|rcsb pdb:2L8E|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|dip:DIP-44567N|uniprotkb:P78364(identity)|entrezgene/locuslink:1911(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:0dDjrgvWcP5Sx8h+qUj7awuM3ko9606 intact-crc:567ED2CE549F4AF2|rigid:hlWa8DjDEoAbPq9IyGU2rgsSccY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:O00257 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835339|imex:IM-21659-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|ddbj/embl/genbank:BC012583(identity)|entrezgene/locuslink:6045(identity) refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|uniprotkb:O00257(identity)|entrezgene/locuslink:8535(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 intact-crc:567ED2CE549F4AF2|rigid:hlWa8DjDEoAbPq9IyGU2rgsSccY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:P61964 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835339|imex:IM-21659-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|ddbj/embl/genbank:BC012583(identity)|entrezgene/locuslink:6045(identity) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|entrezgene/locuslink:11091(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 intact-crc:567ED2CE549F4AF2|rigid:hlWa8DjDEoAbPq9IyGU2rgsSccY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:Q8IXK0 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-713786|uniprotkb:Q8N306|uniprotkb:Q8TAG8|uniprotkb:A1L4Q1|uniprotkb:Q2TAL3|uniprotkb:Q5T0C1|uniprotkb:Q6NUJ6|uniprotkb:Q6ZQR1|uniprotkb:Q96BL4|uniprotkb:Q9Y4Y7|ensembl:ENSP00000257118|uniprotkb:D3DPR2|uniprotkb:A8KA40 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:phc2_human(display_long)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:PHC2(gene name)|psi-mi:PHC2(display_short)|uniprotkb:EDR2(gene name synonym)|uniprotkb:PH2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835339|imex:IM-21659-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|ddbj/embl/genbank:BC012583(identity)|entrezgene/locuslink:6045(identity) interpro:IPR038603|mint:Q8IXK0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR013761(Sterile alpha motif-type)|ensembl:ENSG00000134686(gene)|ensembl:ENST00000257118(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|refseq:NP_004418.2|refseq:NP_932157.1|refseq:XP_016856005.1|refseq:XP_016856006.1|refseq:XP_016856007.1|refseq:XP_005270627.1|dip:DIP-34464N|uniprotkb:Q8IXK0(identity)|entrezgene/locuslink:1912(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:7si/KU2tHoxviuCr70ncQERDWmY9606 intact-crc:567ED2CE549F4AF2|rigid:hlWa8DjDEoAbPq9IyGU2rgsSccY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:Q5H9F3 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-8833946|uniprotkb:Q5H9F4|uniprotkb:Q9Y528|uniprotkb:Q8TEN3|uniprotkb:B5MDQ8|uniprotkb:Q6ZVE0|uniprotkb:Q5H9F2|ensembl:ENSP00000218147|ensembl:ENSP00000437775 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:bcorl_human(display_long)|uniprotkb:BCORL1(gene name)|psi-mi:BCORL1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835339|imex:IM-21659-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|ddbj/embl/genbank:BC012583(identity)|entrezgene/locuslink:6045(identity) ensembl:ENSP00000218147|ensembl:ENSP00000437775|refseq:NP_068765.3|dip:DIP-60148N|ensembl:ENSG00000085185(gene)|ensembl:ENST00000218147(transcript)|ensembl:ENST00000540052(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q5H9F3|rcsb pdb:4HPM|rcsb pdb:5JH5|uniprotkb:Q5H9F3(identity)|entrezgene/locuslink:63035(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:uQdpjjO3QnnX19nR1Ky76HjCdhw9606 intact-crc:567ED2CE549F4AF2|rigid:hlWa8DjDEoAbPq9IyGU2rgsSccY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:Q8IY57 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835339|imex:IM-21659-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|ddbj/embl/genbank:BC012583(identity)|entrezgene/locuslink:6045(identity) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|entrezgene/locuslink:10138(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 intact-crc:567ED2CE549F4AF2|rigid:hlWa8DjDEoAbPq9IyGU2rgsSccY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:Q8N488 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835339|imex:IM-21659-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|ddbj/embl/genbank:BC012583(identity)|entrezgene/locuslink:6045(identity) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|uniprotkb:Q8N488(identity)|entrezgene/locuslink:23429(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 intact-crc:567ED2CE549F4AF2|rigid:hlWa8DjDEoAbPq9IyGU2rgsSccY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:Q86SE9 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835339|imex:IM-21659-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|ddbj/embl/genbank:BC012583(identity)|entrezgene/locuslink:6045(identity) refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N|uniprotkb:Q86SE9(identity)|entrezgene/locuslink:84333(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606 intact-crc:567ED2CE549F4AF2|rigid:hlWa8DjDEoAbPq9IyGU2rgsSccY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:P61962 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835339|imex:IM-21659-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|ddbj/embl/genbank:BC012583(identity)|entrezgene/locuslink:6045(identity) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 intact-crc:567ED2CE549F4AF2|rigid:hlWa8DjDEoAbPq9IyGU2rgsSccY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:P67870 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-348169|ensembl:ENSP00000365025|ensembl:ENSP00000365026|ensembl:ENSP00000365042|ensembl:ENSP00000372919|ensembl:ENSP00000372925|ensembl:ENSP00000382980|ensembl:ENSP00000390900|ensembl:ENSP00000391038|ensembl:ENSP00000393756|ensembl:ENSP00000394855|ensembl:ENSP00000395275|ensembl:ENSP00000400188|ensembl:ENSP00000407018|ensembl:ENSP00000407379|ensembl:ENSP00000409510|ensembl:ENSP00000410802|ensembl:ENSP00000411322|ensembl:ENSP00000412520|ensembl:ENSP00000413469|ensembl:ENSP00000415237|ensembl:ENSP00000415303|uniprotkb:P07312|uniprotkb:P13862|uniprotkb:Q4VX47|intact:EBI-3866975|uniprotkb:B0UXA9 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:csk2b_human(display_long)|uniprotkb:Phosvitin(gene name synonym)|uniprotkb:Protein G5a(gene name synonym)|uniprotkb:CSNK2B(gene name)|psi-mi:CSNK2B(display_short)|uniprotkb:CK2N(gene name synonym)|uniprotkb:G5A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835339|imex:IM-21659-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|ddbj/embl/genbank:BC012583(identity)|entrezgene/locuslink:6045(identity) ensembl:ENSG00000204435(gene)|ensembl:ENSG00000230700(gene)|ensembl:ENSG00000206406(gene)|ensembl:ENSG00000232960(gene)|ensembl:ENSG00000224398(gene)|ensembl:ENSG00000224774(gene)|ensembl:ENSG00000228875(gene)|ensembl:ENST00000375882(transcript)|ensembl:ENST00000383427(transcript)|ensembl:ENST00000383433(transcript)|ensembl:ENST00000400110(transcript)|ensembl:ENST00000412802(transcript)|ensembl:ENST00000418230(transcript)|ensembl:ENST00000422567(transcript)|ensembl:ENST00000429633(transcript)|ensembl:ENST00000431476(transcript)|ensembl:ENST00000436169(transcript)|ensembl:ENST00000443673(transcript)|ensembl:ENST00000448596(transcript)|ensembl:ENST00000451917(transcript)|ensembl:ENST00000452985(transcript)|ensembl:ENST00000453234(transcript)|ensembl:ENST00000454382(transcript)|ensembl:ENST00000454511(transcript)|ensembl:ENST00000455161(transcript)|ensembl:ENST00000458330(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0007165"(signal transduction)|ensembl:ENST00000375865(transcript)|ensembl:ENST00000375866(transcript)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016363"(nuclear matrix)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0034622"|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|mint:P67870|rcsb pdb:1DS5|rcsb pdb:1JWH|go:"GO:0008134"(transcription factor binding)|rcsb pdb:1QF8|rcsb pdb:3EED|rcsb pdb:4DGL|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6798695|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:6Q38|refseq:NP_001311.3|refseq:NP_001269314.1|dip:DIP-131N|uniprotkb:P67870(identity)|entrezgene/locuslink:1460(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:ZTHJjCqHg2dE7B+WoSU28VSMuPg9606 intact-crc:567ED2CE549F4AF2|rigid:hlWa8DjDEoAbPq9IyGU2rgsSccY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:P61244 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835339|imex:IM-21659-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|ddbj/embl/genbank:BC012583(identity)|entrezgene/locuslink:6045(identity) refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750|uniprotkb:P61244(identity)|entrezgene/locuslink:4149(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:I5d1d/zT353OsLios95yEITNoWU9606 intact-crc:567ED2CE549F4AF2|rigid:hlWa8DjDEoAbPq9IyGU2rgsSccY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:Q9HC52 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835339|imex:IM-21659-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|ddbj/embl/genbank:BC012583(identity)|entrezgene/locuslink:6045(identity) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N|uniprotkb:Q9HC52(identity)|entrezgene/locuslink:57332(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 intact-crc:567ED2CE549F4AF2|rigid:hlWa8DjDEoAbPq9IyGU2rgsSccY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:O75461 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835339|imex:IM-21659-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|ddbj/embl/genbank:BC012583(identity)|entrezgene/locuslink:6045(identity) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 intact-crc:567ED2CE549F4AF2|rigid:hlWa8DjDEoAbPq9IyGU2rgsSccY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:Q8NHM5 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-3955564|uniprotkb:Q1RLM7|uniprotkb:Q8NCI2|uniprotkb:Q96HC7|uniprotkb:Q96SL0|uniprotkb:Q96T03|uniprotkb:Q9NS96|uniprotkb:Q9UF75|ensembl:ENSP00000366271|uniprotkb:A8MRS1 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:kdm2b_human(display_long)|uniprotkb:KDM2B(gene name)|psi-mi:KDM2B(display_short)|uniprotkb:CXXC2(gene name synonym)|uniprotkb:FBL10(gene name synonym)|uniprotkb:FBXL10(gene name synonym)|uniprotkb:JHDM1B(gene name synonym)|uniprotkb:PCCX2(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 2(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 10(gene name synonym)|uniprotkb:F-box protein FBL10(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 10(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1B(gene name synonym)|uniprotkb:Jumonji domain-containing EMSY-interactor methyltransferase motif protein(gene name synonym)|uniprotkb:Protein-containing CXXC domain 2(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1B(gene name synonym)|uniprotkb:NDY1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835486|imex:IM-21659-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|uniprotkb:Q8N488(identity)|entrezgene/locuslink:23429(identity)|ddbj/embl/genbank:BC036459(identity) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENST00000377071(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0021555"(midbrain-hindbrain boundary morphogenesis)|go:"GO:0021592"(fourth ventricle development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021678"(third ventricle development)|go:"GO:0021993"(initiation of neural tube closure)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|interpro:IPR041070|interpro:IPR041667|mint:Q8NHM5|rcsb pdb:4O64|rcsb pdb:5JH5|rcsb pdb:6BVA|reactome:R-HSA-3214842|refseq:NP_115979.3|ensembl:ENSG00000089094(gene)|refseq:NP_001005366.1|uniprotkb:Q8NHM5(identity)|entrezgene/locuslink:84678(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:tnMbfP2oxwaaDyHHAigNt5hx4hM9606 intact-crc:C81BBDA8E4423C1F|rigid:YLVaUgov5eY9AXaFPrxum95x4jM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:P61964 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835486|imex:IM-21659-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|uniprotkb:Q8N488(identity)|entrezgene/locuslink:23429(identity)|ddbj/embl/genbank:BC036459(identity) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|entrezgene/locuslink:11091(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 intact-crc:C81BBDA8E4423C1F|rigid:YLVaUgov5eY9AXaFPrxum95x4jM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:P68400 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835486|imex:IM-21659-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|uniprotkb:Q8N488(identity)|entrezgene/locuslink:23429(identity)|ddbj/embl/genbank:BC036459(identity) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N|uniprotkb:P68400(identity)|entrezgene/locuslink:1457(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 intact-crc:C81BBDA8E4423C1F|rigid:YLVaUgov5eY9AXaFPrxum95x4jM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:P61962 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835486|imex:IM-21659-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|uniprotkb:Q8N488(identity)|entrezgene/locuslink:23429(identity)|ddbj/embl/genbank:BC036459(identity) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 intact-crc:C81BBDA8E4423C1F|rigid:YLVaUgov5eY9AXaFPrxum95x4jM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:Q06587 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835486|imex:IM-21659-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|uniprotkb:Q8N488(identity)|entrezgene/locuslink:23429(identity)|ddbj/embl/genbank:BC036459(identity) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 intact-crc:C81BBDA8E4423C1F|rigid:YLVaUgov5eY9AXaFPrxum95x4jM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:P35227 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-2129767|uniprotkb:A6NGD8|ensembl:ENSP00000478517|ensembl:ENSP00000478970|ensembl:ENSP00000482063|ensembl:ENSP00000482815|ensembl:ENSP00000488868|ensembl:ENSP00000488872 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:pcgf2_human(display_long)|uniprotkb:PCGF2(gene name)|psi-mi:PCGF2(display_short)|uniprotkb:MEL18(gene name synonym)|uniprotkb:RNF110(gene name synonym)|uniprotkb:ZNF144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835486|imex:IM-21659-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|uniprotkb:Q8N488(identity)|entrezgene/locuslink:23429(identity)|ddbj/embl/genbank:BC036459(identity) refseq:NP_009075.1|refseq:XP_016880505.1|refseq:XP_005257697.1|refseq:XP_005257698.1|refseq:XP_005257699.1|dip:DIP-41880N|ensembl:ENSG00000277258(gene)|ensembl:ENSG00000278644(gene)|ensembl:ENST00000610440(transcript)|ensembl:ENST00000611883(transcript)|ensembl:ENST00000616199(transcript)|ensembl:ENST00000620225(transcript)|ensembl:ENST00000631566(transcript)|ensembl:ENST00000631610(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35227|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-5617472|reactome:R-HSA-8953750|uniprotkb:P35227(identity)|entrezgene/locuslink:7703(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:zppw56VrEl6gEFwtJMCN5cQkPxI9606 intact-crc:C81BBDA8E4423C1F|rigid:YLVaUgov5eY9AXaFPrxum95x4jM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:P67870 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-348169|ensembl:ENSP00000365025|ensembl:ENSP00000365026|ensembl:ENSP00000365042|ensembl:ENSP00000372919|ensembl:ENSP00000372925|ensembl:ENSP00000382980|ensembl:ENSP00000390900|ensembl:ENSP00000391038|ensembl:ENSP00000393756|ensembl:ENSP00000394855|ensembl:ENSP00000395275|ensembl:ENSP00000400188|ensembl:ENSP00000407018|ensembl:ENSP00000407379|ensembl:ENSP00000409510|ensembl:ENSP00000410802|ensembl:ENSP00000411322|ensembl:ENSP00000412520|ensembl:ENSP00000413469|ensembl:ENSP00000415237|ensembl:ENSP00000415303|uniprotkb:P07312|uniprotkb:P13862|uniprotkb:Q4VX47|intact:EBI-3866975|uniprotkb:B0UXA9 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:csk2b_human(display_long)|uniprotkb:Phosvitin(gene name synonym)|uniprotkb:Protein G5a(gene name synonym)|uniprotkb:CSNK2B(gene name)|psi-mi:CSNK2B(display_short)|uniprotkb:CK2N(gene name synonym)|uniprotkb:G5A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835486|imex:IM-21659-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|uniprotkb:Q8N488(identity)|entrezgene/locuslink:23429(identity)|ddbj/embl/genbank:BC036459(identity) ensembl:ENSG00000204435(gene)|ensembl:ENSG00000230700(gene)|ensembl:ENSG00000206406(gene)|ensembl:ENSG00000232960(gene)|ensembl:ENSG00000224398(gene)|ensembl:ENSG00000224774(gene)|ensembl:ENSG00000228875(gene)|ensembl:ENST00000375882(transcript)|ensembl:ENST00000383427(transcript)|ensembl:ENST00000383433(transcript)|ensembl:ENST00000400110(transcript)|ensembl:ENST00000412802(transcript)|ensembl:ENST00000418230(transcript)|ensembl:ENST00000422567(transcript)|ensembl:ENST00000429633(transcript)|ensembl:ENST00000431476(transcript)|ensembl:ENST00000436169(transcript)|ensembl:ENST00000443673(transcript)|ensembl:ENST00000448596(transcript)|ensembl:ENST00000451917(transcript)|ensembl:ENST00000452985(transcript)|ensembl:ENST00000453234(transcript)|ensembl:ENST00000454382(transcript)|ensembl:ENST00000454511(transcript)|ensembl:ENST00000455161(transcript)|ensembl:ENST00000458330(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0007165"(signal transduction)|ensembl:ENST00000375865(transcript)|ensembl:ENST00000375866(transcript)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016363"(nuclear matrix)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0034622"|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|mint:P67870|rcsb pdb:1DS5|rcsb pdb:1JWH|go:"GO:0008134"(transcription factor binding)|rcsb pdb:1QF8|rcsb pdb:3EED|rcsb pdb:4DGL|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6798695|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:6Q38|refseq:NP_001311.3|refseq:NP_001269314.1|dip:DIP-131N|uniprotkb:P67870(identity)|entrezgene/locuslink:1460(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:ZTHJjCqHg2dE7B+WoSU28VSMuPg9606 intact-crc:C81BBDA8E4423C1F|rigid:YLVaUgov5eY9AXaFPrxum95x4jM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:Q6W2J9 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835486|imex:IM-21659-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|uniprotkb:Q8N488(identity)|entrezgene/locuslink:23429(identity)|ddbj/embl/genbank:BC036459(identity) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N|uniprotkb:Q6W2J9(identity)|entrezgene/locuslink:54880(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 intact-crc:C81BBDA8E4423C1F|rigid:YLVaUgov5eY9AXaFPrxum95x4jM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:Q99496 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835486|imex:IM-21659-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|uniprotkb:Q8N488(identity)|entrezgene/locuslink:23429(identity)|ddbj/embl/genbank:BC036459(identity) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|entrezgene/locuslink:6045(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 intact-crc:C81BBDA8E4423C1F|rigid:YLVaUgov5eY9AXaFPrxum95x4jM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:P83916 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835486|imex:IM-21659-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|uniprotkb:Q8N488(identity)|entrezgene/locuslink:23429(identity)|ddbj/embl/genbank:BC036459(identity) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|entrezgene/locuslink:10951(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 intact-crc:C81BBDA8E4423C1F|rigid:YLVaUgov5eY9AXaFPrxum95x4jM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:Q5H9F3 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-8833946|uniprotkb:Q5H9F4|uniprotkb:Q9Y528|uniprotkb:Q8TEN3|uniprotkb:B5MDQ8|uniprotkb:Q6ZVE0|uniprotkb:Q5H9F2|ensembl:ENSP00000218147|ensembl:ENSP00000437775 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:bcorl_human(display_long)|uniprotkb:BCORL1(gene name)|psi-mi:BCORL1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835486|imex:IM-21659-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|uniprotkb:Q8N488(identity)|entrezgene/locuslink:23429(identity)|ddbj/embl/genbank:BC036459(identity) ensembl:ENSP00000218147|ensembl:ENSP00000437775|refseq:NP_068765.3|dip:DIP-60148N|ensembl:ENSG00000085185(gene)|ensembl:ENST00000218147(transcript)|ensembl:ENST00000540052(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q5H9F3|rcsb pdb:4HPM|rcsb pdb:5JH5|uniprotkb:Q5H9F3(identity)|entrezgene/locuslink:63035(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:uQdpjjO3QnnX19nR1Ky76HjCdhw9606 intact-crc:C81BBDA8E4423C1F|rigid:YLVaUgov5eY9AXaFPrxum95x4jM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:Q9HCM7 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-6255777|ensembl:ENSP00000396160|uniprotkb:Q86XQ1 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:fbsl_human(display_long)|uniprotkb:FBRSL1(gene name)|psi-mi:FBRSL1(display_short)|uniprotkb:AUTS2L(gene name synonym)|uniprotkb:KIAA1545(gene name synonym)|uniprotkb:XTP9(gene name synonym)|uniprotkb:AUTS2-like protein(gene name synonym)|uniprotkb:HBV X-transactivated gene 9 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835486|imex:IM-21659-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|uniprotkb:Q8N488(identity)|entrezgene/locuslink:23429(identity)|ddbj/embl/genbank:BC036459(identity) ensembl:ENSG00000112787(gene)|ensembl:ENST00000434748(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR023246|refseq:NP_001136113.1|uniprotkb:Q9HCM7(identity)|entrezgene/locuslink:57666(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:JstP98Bp/L0+GmkLfSdhDHnWmiU9606 intact-crc:C81BBDA8E4423C1F|rigid:YLVaUgov5eY9AXaFPrxum95x4jM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:P19784 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-347451|ensembl:ENSP00000262506 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835486|imex:IM-21659-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|uniprotkb:Q8N488(identity)|entrezgene/locuslink:23429(identity)|ddbj/embl/genbank:BC036459(identity) refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|uniprotkb:P19784(identity)|entrezgene/locuslink:1459(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 intact-crc:C81BBDA8E4423C1F|rigid:YLVaUgov5eY9AXaFPrxum95x4jM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:Q9HAH7 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-2847800|uniprotkb:Q9H9X4|uniprotkb:Q96CI9|uniprotkb:B4DP86|ensembl:ENSP00000287468 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:fbrs_human(display_long)|uniprotkb:FBRS(gene name)|psi-mi:FBRS(display_short)|uniprotkb:FBS(gene name synonym)|uniprotkb:FBS1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835486|imex:IM-21659-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|uniprotkb:Q8N488(identity)|entrezgene/locuslink:23429(identity)|ddbj/embl/genbank:BC036459(identity) refseq:NP_001098549.2|dip:DIP-61357N|ensembl:ENSG00000156860(gene)|ensembl:ENST00000287468(transcript)|interpro:IPR023246|mint:Q9HAH7|uniprotkb:Q9HAH7(identity)|entrezgene/locuslink:64319(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:n1zkWAYdgwY+t7CFWg5RKO1VSfE9606 intact-crc:C81BBDA8E4423C1F|rigid:YLVaUgov5eY9AXaFPrxum95x4jM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:Q3KNV8 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-2339807|uniprotkb:O15262|uniprotkb:D3DVN1|ensembl:ENSP00000354724|ensembl:ENSP00000420489 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:pcgf3_human(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835486|imex:IM-21659-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|uniprotkb:Q8N488(identity)|entrezgene/locuslink:23429(identity)|ddbj/embl/genbank:BC036459(identity) refseq:NP_006306.2|refseq:NP_001304765.1|dip:DIP-52782N|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q3KNV8|uniprotkb:Q3KNV8(identity)|entrezgene/locuslink:10336(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606 intact-crc:C81BBDA8E4423C1F|rigid:YLVaUgov5eY9AXaFPrxum95x4jM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:P35226 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835486|imex:IM-21659-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|uniprotkb:Q8N488(identity)|entrezgene/locuslink:23429(identity)|ddbj/embl/genbank:BC036459(identity) refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:P35226(identity)|entrezgene/locuslink:100532731(identity)|entrezgene/locuslink:648(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606 intact-crc:C81BBDA8E4423C1F|rigid:YLVaUgov5eY9AXaFPrxum95x4jM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:Q9BYE7 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835486|imex:IM-21659-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|uniprotkb:Q8N488(identity)|entrezgene/locuslink:23429(identity)|ddbj/embl/genbank:BC036459(identity) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 intact-crc:C81BBDA8E4423C1F|rigid:YLVaUgov5eY9AXaFPrxum95x4jM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:Q8WXX7 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-2875359|ensembl:ENSP00000344087|uniprotkb:L7QET3|uniprotkb:L7QF75|uniprotkb:Q5D049|uniprotkb:Q9Y4F2|uniprotkb:A4D1Y9|uniprotkb:Q6PJU5 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:auts2_human(display_long)|uniprotkb:AUTS2(gene name)|psi-mi:AUTS2(display_short)|uniprotkb:KIAA0442(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835486|imex:IM-21659-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|uniprotkb:Q8N488(identity)|entrezgene/locuslink:23429(identity)|ddbj/embl/genbank:BC036459(identity) ensembl:ENSG00000158321(gene)|ensembl:ENST00000342771(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048675"(axon extension)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0097484"(dendrite extension)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR023246|reactome:R-HSA-8939243|refseq:NP_001120703.1|refseq:NP_001120704.1|refseq:NP_056385.1|dip:DIP-61355N|uniprotkb:Q8WXX7(identity)|entrezgene/locuslink:26053(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:8m3VWlXEISEyVwNmlwDFEEKl4Sg9606 intact-crc:C81BBDA8E4423C1F|rigid:YLVaUgov5eY9AXaFPrxum95x4jM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:Q13185 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835486|imex:IM-21659-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|uniprotkb:Q8N488(identity)|entrezgene/locuslink:23429(identity)|ddbj/embl/genbank:BC036459(identity) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 intact-crc:C81BBDA8E4423C1F|rigid:YLVaUgov5eY9AXaFPrxum95x4jM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:Q86SE9 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835486|imex:IM-21659-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|uniprotkb:Q8N488(identity)|entrezgene/locuslink:23429(identity)|ddbj/embl/genbank:BC036459(identity) refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N|uniprotkb:Q86SE9(identity)|entrezgene/locuslink:84333(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606 intact-crc:C81BBDA8E4423C1F|rigid:YLVaUgov5eY9AXaFPrxum95x4jM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:Q969R5 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835486|imex:IM-21659-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|uniprotkb:Q8N488(identity)|entrezgene/locuslink:23429(identity)|ddbj/embl/genbank:BC036459(identity) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750|uniprotkb:Q969R5(identity)|entrezgene/locuslink:83746(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 intact-crc:C81BBDA8E4423C1F|rigid:YLVaUgov5eY9AXaFPrxum95x4jM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:P63208 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835486|imex:IM-21659-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|uniprotkb:Q8N488(identity)|entrezgene/locuslink:23429(identity)|ddbj/embl/genbank:BC036459(identity) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|entrezgene/locuslink:6500(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 intact-crc:C81BBDA8E4423C1F|rigid:YLVaUgov5eY9AXaFPrxum95x4jM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:Q9BSM1 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835486|imex:IM-21659-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|uniprotkb:Q8N488(identity)|entrezgene/locuslink:23429(identity)|ddbj/embl/genbank:BC036459(identity) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5|uniprotkb:Q9BSM1(identity)|entrezgene/locuslink:84759(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 intact-crc:C81BBDA8E4423C1F|rigid:YLVaUgov5eY9AXaFPrxum95x4jM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:P61244 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835486|imex:IM-21659-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|uniprotkb:Q8N488(identity)|entrezgene/locuslink:23429(identity)|ddbj/embl/genbank:BC036459(identity) refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750|uniprotkb:P61244(identity)|entrezgene/locuslink:4149(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:I5d1d/zT353OsLios95yEITNoWU9606 intact-crc:C81BBDA8E4423C1F|rigid:YLVaUgov5eY9AXaFPrxum95x4jM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:Q8IWI9 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-2815196|uniprotkb:E7ENI0|uniprotkb:F5H7K2|uniprotkb:Q9H9N7|uniprotkb:Q9H8R3|uniprotkb:Q9Y4E9|uniprotkb:Q9UG69|intact:EBI-11143500|intact:EBI-10969960|ensembl:ENSP00000219905|uniprotkb:B9EGR5 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:mgap_human(display_long)|uniprotkb:MGA(gene name)|psi-mi:MGA(display_short)|uniprotkb:KIAA0518(gene name synonym)|uniprotkb:MAD5(gene name synonym)|uniprotkb:MAX dimerization protein 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835486|imex:IM-21659-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|uniprotkb:Q8N488(identity)|entrezgene/locuslink:23429(identity)|ddbj/embl/genbank:BC036459(identity) refseq:NP_001074010.2|ensembl:ENSP00000219905|ensembl:ENST00000566586|ensembl:ENSP00000456141|ensembl:ENSG00000174197(gene)|ensembl:ENST00000219905(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR018186|interpro:IPR032060|interpro:IPR036638|interpro:IPR036960|interpro:IPR037935|mint:Q8IWI9|reactome:R-HSA-8953750|refseq:NP_001157745.1|dip:DIP-57615N|uniprotkb:Q8IWI9(identity)|entrezgene/locuslink:23269(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:P4lo9EteCvikQQk5kyVkcobitLU9606 intact-crc:C81BBDA8E4423C1F|rigid:YLVaUgov5eY9AXaFPrxum95x4jM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:O75461 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835486|imex:IM-21659-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|uniprotkb:Q8N488(identity)|entrezgene/locuslink:23429(identity)|ddbj/embl/genbank:BC036459(identity) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 intact-crc:C81BBDA8E4423C1F|rigid:YLVaUgov5eY9AXaFPrxum95x4jM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:Q14186 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835486|imex:IM-21659-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|uniprotkb:Q8N488(identity)|entrezgene/locuslink:23429(identity)|ddbj/embl/genbank:BC036459(identity) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|entrezgene/locuslink:7027(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 intact-crc:C81BBDA8E4423C1F|rigid:YLVaUgov5eY9AXaFPrxum95x4jM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BQF6 uniprotkb:Q96JM3 intact:EBI-766251|uniprotkb:Q7Z3F4|uniprotkb:Q96PS5|uniprotkb:Q9C0F6|uniprotkb:Q9HBT5|uniprotkb:A1L3A5|uniprotkb:A8MW39|uniprotkb:B7WNW8|ensembl:ENSP00000377655 intact:EBI-2560420|uniprotkb:Q8NC88|uniprotkb:B3KU06|uniprotkb:Q6P181|uniprotkb:Q9BST0|ensembl:ENSP00000354730|ensembl:ENSP00000496699 psi-mi:senp7_human(display_long)|uniprotkb:SUMO-1-specific protease 2(gene name synonym)|uniprotkb:Sentrin/SUMO-specific protease SENP7(gene name synonym)|uniprotkb:SENP7(gene name)|psi-mi:SENP7(display_short)|uniprotkb:KIAA1707(gene name synonym)|uniprotkb:SSP2(gene name synonym)|uniprotkb:SUSP2(gene name synonym) psi-mi:chap1_human(display_long)|uniprotkb:CHAMP(gene name synonym)|uniprotkb:CHAMP1(gene name)|psi-mi:CHAMP1(display_short)|uniprotkb:C13orf8(gene name synonym)|uniprotkb:CAMP(gene name synonym)|uniprotkb:KIAA1802(gene name synonym)|uniprotkb:ZNF828(gene name synonym)|uniprotkb:Zinc finger protein 828(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835605|imex:IM-21659-50 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001070671.1|refseq:NP_001269730.1|refseq:NP_001269731.1|refseq:NP_001269732.1|refseq:NP_001269733.1|refseq:NP_065705.3|refseq:XP_016862414.1|ensembl:ENSG00000138468(gene)|ensembl:ENST00000394095(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016926"(protein desumoylation)|go:"GO:0070139"(SUMO-specific endopeptidase activity)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|rcsb pdb:3EAY|interpro:IPR038765|uniprotkb:Q9BQF6(identity)|ddbj/embl/genbank:BC129988(identity)|entrezgene/locuslink:57337(identity) refseq:NP_001157616.1|refseq:NP_001157617.1|refseq:NP_115812.1|ensembl:ENSG00000198824(gene)|ensembl:ENST00000361283(transcript)|ensembl:ENST00000643483(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0016604"(nuclear body)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0046872"(metal ion binding)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0090543"(Flemming body)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR039330|mint:Q96JM3|rcsb pdb:6EKJ|rcsb pdb:6EKL|rcsb pdb:5XPT|rcsb pdb:5XPU|uniprotkb:Q96JM3(identity)|entrezgene/locuslink:283489(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dLL7YHqSkqW17N+IHtiDf0yC07Q9606 rogid:Di1yMiufHKsy384vPjOgdncmQXw9606 intact-crc:AC9383D2A9BB6DED|rigid:ycWRWqe6lPRzWGoMbivHrUqODLg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BQF6 uniprotkb:Q5TGY3 intact:EBI-766251|uniprotkb:Q7Z3F4|uniprotkb:Q96PS5|uniprotkb:Q9C0F6|uniprotkb:Q9HBT5|uniprotkb:A1L3A5|uniprotkb:A8MW39|uniprotkb:B7WNW8|ensembl:ENSP00000377655 intact:EBI-948813|ensembl:ENSP00000247087|ensembl:ENSP00000363123|ensembl:ENSP00000494394|ensembl:ENSP00000495072|ensembl:ENSP00000495665|ensembl:ENSP00000501218|uniprotkb:Q5TGY4|uniprotkb:Q6PJK1|uniprotkb:Q6ZUQ6|uniprotkb:Q99769|uniprotkb:Q9NUF5 psi-mi:senp7_human(display_long)|uniprotkb:SUMO-1-specific protease 2(gene name synonym)|uniprotkb:Sentrin/SUMO-specific protease SENP7(gene name synonym)|uniprotkb:SENP7(gene name)|psi-mi:SENP7(display_short)|uniprotkb:KIAA1707(gene name synonym)|uniprotkb:SSP2(gene name synonym)|uniprotkb:SUSP2(gene name synonym) psi-mi:ahdc1_human(display_long)|uniprotkb:AHDC1(gene name)|psi-mi:AHDC1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835605|imex:IM-21659-50 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001070671.1|refseq:NP_001269730.1|refseq:NP_001269731.1|refseq:NP_001269732.1|refseq:NP_001269733.1|refseq:NP_065705.3|refseq:XP_016862414.1|ensembl:ENSG00000138468(gene)|ensembl:ENST00000394095(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016926"(protein desumoylation)|go:"GO:0070139"(SUMO-specific endopeptidase activity)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|rcsb pdb:3EAY|interpro:IPR038765|uniprotkb:Q9BQF6(identity)|ddbj/embl/genbank:BC129988(identity)|entrezgene/locuslink:57337(identity) ensembl:ENSG00000126705(gene)|ensembl:ENST00000247087(transcript)|ensembl:ENST00000374011(transcript)|ensembl:ENST00000642245(transcript)|ensembl:ENST00000642416(transcript)|ensembl:ENST00000644989(transcript)|ensembl:ENST00000673934(transcript)|go:"GO:0003677"(DNA binding)|interpro:IPR032757|interpro:IPR039225|mint:Q5TGY3|refseq:NP_001025053.1|refseq:XP_011539557.1|refseq:XP_011539558.1|refseq:XP_011539559.1|refseq:XP_005245905.1|refseq:XP_005245906.1|refseq:XP_005245907.1|refseq:XP_005245908.1|refseq:XP_005245909.1|uniprotkb:Q5TGY3(identity)|entrezgene/locuslink:27245(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dLL7YHqSkqW17N+IHtiDf0yC07Q9606 rogid:lYUJEAEhxO204mZnqOd4Vf6K/g89606 intact-crc:AC9383D2A9BB6DED|rigid:ycWRWqe6lPRzWGoMbivHrUqODLg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BQF6 uniprotkb:O14950 intact:EBI-766251|uniprotkb:Q7Z3F4|uniprotkb:Q96PS5|uniprotkb:Q9C0F6|uniprotkb:Q9HBT5|uniprotkb:A1L3A5|uniprotkb:A8MW39|uniprotkb:B7WNW8|ensembl:ENSP00000377655 intact:EBI-1642165|uniprotkb:D3DUH6|intact:EBI-2826593|uniprotkb:Q7Z5Z4|uniprotkb:Q13182|ensembl:ENSP00000237500|ensembl:ENSP00000383037|ensembl:ENSP00000463559|ensembl:ENSP00000464464|ensembl:ENSP00000496809 psi-mi:senp7_human(display_long)|uniprotkb:SUMO-1-specific protease 2(gene name synonym)|uniprotkb:Sentrin/SUMO-specific protease SENP7(gene name synonym)|uniprotkb:SENP7(gene name)|psi-mi:SENP7(display_short)|uniprotkb:KIAA1707(gene name synonym)|uniprotkb:SSP2(gene name synonym)|uniprotkb:SUSP2(gene name synonym) psi-mi:ml12b_human(display_long)|uniprotkb:MYL12B(gene name)|psi-mi:MYL12B(display_short)|uniprotkb:MRLC2(gene name synonym)|uniprotkb:Myosin regulatory light chain 2-B, smooth muscle isoform(gene name synonym)|uniprotkb:MLC-2A(gene name synonym)|uniprotkb:SHUJUN-1(gene name synonym)|uniprotkb:MYLC2B(gene name synonym)|uniprotkb:Myosin regulatory light chain MRLC2(gene name synonym)|uniprotkb:Myosin regulatory light chain 20 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835605|imex:IM-21659-50 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001070671.1|refseq:NP_001269730.1|refseq:NP_001269731.1|refseq:NP_001269732.1|refseq:NP_001269733.1|refseq:NP_065705.3|refseq:XP_016862414.1|ensembl:ENSG00000138468(gene)|ensembl:ENST00000394095(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016926"(protein desumoylation)|go:"GO:0070139"(SUMO-specific endopeptidase activity)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|rcsb pdb:3EAY|interpro:IPR038765|uniprotkb:Q9BQF6(identity)|ddbj/embl/genbank:BC129988(identity)|entrezgene/locuslink:57337(identity) refseq:NP_001138416.1|refseq:NP_001138417.1|refseq:NP_291024.1|refseq:NP_001289978.1|ensembl:ENSG00000118680(gene)|ensembl:ENST00000237500(transcript)|ensembl:ENST00000400175(transcript)|ensembl:ENST00000581193(transcript)|ensembl:ENST00000584539(transcript)|ensembl:ENST00000648965(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016460"(myosin II complex)|go:"GO:0030018"(Z disc)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR015070(Region of unknown function DUF1880)|interpro:IPR018247|mint:O14950|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|uniprotkb:O14950(identity)|entrezgene/locuslink:103910(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dLL7YHqSkqW17N+IHtiDf0yC07Q9606 rogid:5jOP3J5TW0eU9zwalQ2S4Oist4k9606 intact-crc:AC9383D2A9BB6DED|rigid:ycWRWqe6lPRzWGoMbivHrUqODLg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BQF6 uniprotkb:P01040 intact:EBI-766251|uniprotkb:Q7Z3F4|uniprotkb:Q96PS5|uniprotkb:Q9C0F6|uniprotkb:Q9HBT5|uniprotkb:A1L3A5|uniprotkb:A8MW39|uniprotkb:B7WNW8|ensembl:ENSP00000377655 intact:EBI-724303|ensembl:ENSP00000264474|uniprotkb:Q6IB90 psi-mi:senp7_human(display_long)|uniprotkb:SUMO-1-specific protease 2(gene name synonym)|uniprotkb:Sentrin/SUMO-specific protease SENP7(gene name synonym)|uniprotkb:SENP7(gene name)|psi-mi:SENP7(display_short)|uniprotkb:KIAA1707(gene name synonym)|uniprotkb:SSP2(gene name synonym)|uniprotkb:SUSP2(gene name synonym) psi-mi:cyta_human(display_long)|uniprotkb:Cystatin-AS(gene name synonym)|uniprotkb:Stefin-A(gene name synonym)|uniprotkb:CSTA(gene name)|psi-mi:CSTA(display_short)|uniprotkb:STF1(gene name synonym)|uniprotkb:STFA(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835605|imex:IM-21659-50 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001070671.1|refseq:NP_001269730.1|refseq:NP_001269731.1|refseq:NP_001269732.1|refseq:NP_001269733.1|refseq:NP_065705.3|refseq:XP_016862414.1|ensembl:ENSG00000138468(gene)|ensembl:ENST00000394095(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016926"(protein desumoylation)|go:"GO:0070139"(SUMO-specific endopeptidase activity)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|rcsb pdb:3EAY|interpro:IPR038765|uniprotkb:Q9BQF6(identity)|ddbj/embl/genbank:BC129988(identity)|entrezgene/locuslink:57337(identity) refseq:NP_005204.1|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR001713(Proteinase inhibitor I25A, stefin A)|mint:P01040|rcsb pdb:1CYU|rcsb pdb:1CYV|rcsb pdb:1DVC|rcsb pdb:1DVD|rcsb pdb:1GD3|rcsb pdb:1GD4|rcsb pdb:1N9J|rcsb pdb:1NB3|rcsb pdb:1NB5|rcsb pdb:3K9M|rcsb pdb:3KFQ|interpro:IPR018073|rcsb pdb:3KSE|reactome:R-HSA-6809371|ensembl:ENSG00000121552(gene)|ensembl:ENST00000264474(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002020"(protease binding)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0045861"(negative regulation of proteolysis)|uniprotkb:P01040(identity)|entrezgene/locuslink:1475(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dLL7YHqSkqW17N+IHtiDf0yC07Q9606 rogid:SzbpyWUHlOtItIvffzuwhcqFsDI9606 intact-crc:AC9383D2A9BB6DED|rigid:ycWRWqe6lPRzWGoMbivHrUqODLg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BQF6 uniprotkb:P45973 intact:EBI-766251|uniprotkb:Q7Z3F4|uniprotkb:Q96PS5|uniprotkb:Q9C0F6|uniprotkb:Q9HBT5|uniprotkb:A1L3A5|uniprotkb:A8MW39|uniprotkb:B7WNW8|ensembl:ENSP00000377655 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 psi-mi:senp7_human(display_long)|uniprotkb:SUMO-1-specific protease 2(gene name synonym)|uniprotkb:Sentrin/SUMO-specific protease SENP7(gene name synonym)|uniprotkb:SENP7(gene name)|psi-mi:SENP7(display_short)|uniprotkb:KIAA1707(gene name synonym)|uniprotkb:SSP2(gene name synonym)|uniprotkb:SUSP2(gene name synonym) psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835605|imex:IM-21659-50 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001070671.1|refseq:NP_001269730.1|refseq:NP_001269731.1|refseq:NP_001269732.1|refseq:NP_001269733.1|refseq:NP_065705.3|refseq:XP_016862414.1|ensembl:ENSG00000138468(gene)|ensembl:ENST00000394095(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016926"(protein desumoylation)|go:"GO:0070139"(SUMO-specific endopeptidase activity)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|rcsb pdb:3EAY|interpro:IPR038765|uniprotkb:Q9BQF6(identity)|ddbj/embl/genbank:BC129988(identity)|entrezgene/locuslink:57337(identity) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|entrezgene/locuslink:23468(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dLL7YHqSkqW17N+IHtiDf0yC07Q9606 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 intact-crc:AC9383D2A9BB6DED|rigid:ycWRWqe6lPRzWGoMbivHrUqODLg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BQF6 uniprotkb:Q13185 intact:EBI-766251|uniprotkb:Q7Z3F4|uniprotkb:Q96PS5|uniprotkb:Q9C0F6|uniprotkb:Q9HBT5|uniprotkb:A1L3A5|uniprotkb:A8MW39|uniprotkb:B7WNW8|ensembl:ENSP00000377655 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:senp7_human(display_long)|uniprotkb:SUMO-1-specific protease 2(gene name synonym)|uniprotkb:Sentrin/SUMO-specific protease SENP7(gene name synonym)|uniprotkb:SENP7(gene name)|psi-mi:SENP7(display_short)|uniprotkb:KIAA1707(gene name synonym)|uniprotkb:SSP2(gene name synonym)|uniprotkb:SUSP2(gene name synonym) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835605|imex:IM-21659-50 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001070671.1|refseq:NP_001269730.1|refseq:NP_001269731.1|refseq:NP_001269732.1|refseq:NP_001269733.1|refseq:NP_065705.3|refseq:XP_016862414.1|ensembl:ENSG00000138468(gene)|ensembl:ENST00000394095(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016926"(protein desumoylation)|go:"GO:0070139"(SUMO-specific endopeptidase activity)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|rcsb pdb:3EAY|interpro:IPR038765|uniprotkb:Q9BQF6(identity)|ddbj/embl/genbank:BC129988(identity)|entrezgene/locuslink:57337(identity) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dLL7YHqSkqW17N+IHtiDf0yC07Q9606 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 intact-crc:AC9383D2A9BB6DED|rigid:ycWRWqe6lPRzWGoMbivHrUqODLg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BQF6 uniprotkb:Q13263 intact:EBI-766251|uniprotkb:Q7Z3F4|uniprotkb:Q96PS5|uniprotkb:Q9C0F6|uniprotkb:Q9HBT5|uniprotkb:A1L3A5|uniprotkb:A8MW39|uniprotkb:B7WNW8|ensembl:ENSP00000377655 intact:EBI-78139|uniprotkb:O00677|ensembl:ENSP00000253024|uniprotkb:Q7Z632|uniprotkb:Q93040|uniprotkb:Q96IM1 psi-mi:senp7_human(display_long)|uniprotkb:SUMO-1-specific protease 2(gene name synonym)|uniprotkb:Sentrin/SUMO-specific protease SENP7(gene name synonym)|uniprotkb:SENP7(gene name)|psi-mi:SENP7(display_short)|uniprotkb:KIAA1707(gene name synonym)|uniprotkb:SSP2(gene name synonym)|uniprotkb:SUSP2(gene name synonym) psi-mi:tif1b_human(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835605|imex:IM-21659-50 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001070671.1|refseq:NP_001269730.1|refseq:NP_001269731.1|refseq:NP_001269732.1|refseq:NP_001269733.1|refseq:NP_065705.3|refseq:XP_016862414.1|ensembl:ENSG00000138468(gene)|ensembl:ENST00000394095(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016926"(protein desumoylation)|go:"GO:0070139"(SUMO-specific endopeptidase activity)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|rcsb pdb:3EAY|interpro:IPR038765|uniprotkb:Q9BQF6(identity)|ddbj/embl/genbank:BC129988(identity)|entrezgene/locuslink:57337(identity) ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6QAJ|rcsb pdb:6QU1|reactome:R-HSA-212436|reactome:R-HSA-3899300|reactome:R-HSA-9609690|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q13263|rcsb pdb:1FP0|rcsb pdb:2RO1|rcsb pdb:2YVR|rcsb pdb:6H3A|rcsb pdb:6I9H|refseq:NP_005753.1|dip:DIP-30891N|uniprotkb:Q13263(identity)|entrezgene/locuslink:10155(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dLL7YHqSkqW17N+IHtiDf0yC07Q9606 rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606 intact-crc:AC9383D2A9BB6DED|rigid:ycWRWqe6lPRzWGoMbivHrUqODLg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BQF6 uniprotkb:Q09028 intact:EBI-766251|uniprotkb:Q7Z3F4|uniprotkb:Q96PS5|uniprotkb:Q9C0F6|uniprotkb:Q9HBT5|uniprotkb:A1L3A5|uniprotkb:A8MW39|uniprotkb:B7WNW8|ensembl:ENSP00000377655 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 psi-mi:senp7_human(display_long)|uniprotkb:SUMO-1-specific protease 2(gene name synonym)|uniprotkb:Sentrin/SUMO-specific protease SENP7(gene name synonym)|uniprotkb:SENP7(gene name)|psi-mi:SENP7(display_short)|uniprotkb:KIAA1707(gene name synonym)|uniprotkb:SSP2(gene name synonym)|uniprotkb:SUSP2(gene name synonym) psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835605|imex:IM-21659-50 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001070671.1|refseq:NP_001269730.1|refseq:NP_001269731.1|refseq:NP_001269732.1|refseq:NP_001269733.1|refseq:NP_065705.3|refseq:XP_016862414.1|ensembl:ENSG00000138468(gene)|ensembl:ENST00000394095(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016926"(protein desumoylation)|go:"GO:0070139"(SUMO-specific endopeptidase activity)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|rcsb pdb:3EAY|interpro:IPR038765|uniprotkb:Q9BQF6(identity)|ddbj/embl/genbank:BC129988(identity)|entrezgene/locuslink:57337(identity) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|entrezgene/locuslink:5928(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:dLL7YHqSkqW17N+IHtiDf0yC07Q9606 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 intact-crc:AC9383D2A9BB6DED|rigid:ycWRWqe6lPRzWGoMbivHrUqODLg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q8NHM5 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-3955564|uniprotkb:Q1RLM7|uniprotkb:Q8NCI2|uniprotkb:Q96HC7|uniprotkb:Q96SL0|uniprotkb:Q96T03|uniprotkb:Q9NS96|uniprotkb:Q9UF75|ensembl:ENSP00000366271|uniprotkb:A8MRS1 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:kdm2b_human(display_long)|uniprotkb:KDM2B(gene name)|psi-mi:KDM2B(display_short)|uniprotkb:CXXC2(gene name synonym)|uniprotkb:FBL10(gene name synonym)|uniprotkb:FBXL10(gene name synonym)|uniprotkb:JHDM1B(gene name synonym)|uniprotkb:PCCX2(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 2(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 10(gene name synonym)|uniprotkb:F-box protein FBL10(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 10(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1B(gene name synonym)|uniprotkb:Jumonji domain-containing EMSY-interactor methyltransferase motif protein(gene name synonym)|uniprotkb:Protein-containing CXXC domain 2(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1B(gene name synonym)|uniprotkb:NDY1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENST00000377071(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0021555"(midbrain-hindbrain boundary morphogenesis)|go:"GO:0021592"(fourth ventricle development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021678"(third ventricle development)|go:"GO:0021993"(initiation of neural tube closure)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|interpro:IPR041070|interpro:IPR041667|mint:Q8NHM5|rcsb pdb:4O64|rcsb pdb:5JH5|rcsb pdb:6BVA|reactome:R-HSA-3214842|refseq:NP_115979.3|ensembl:ENSG00000089094(gene)|refseq:NP_001005366.1|uniprotkb:Q8NHM5(identity)|entrezgene/locuslink:84678(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:tnMbfP2oxwaaDyHHAigNt5hx4hM9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q96ME1 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-6425558|uniprotkb:Q9BR90|uniprotkb:Q9HAK7|uniprotkb:Q9BTC7 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fxl18_human(display_long)|uniprotkb:FBXL18(gene name)|psi-mi:FBXL18(display_short)|uniprotkb:F-box and leucine-rich repeat protein 18(gene name synonym)|uniprotkb:FBL18(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) go:"GO:0005829"(cytosol)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR032675|reactome:R-HSA-8854050|reactome:R-HSA-983168|reactome:R-HSA-8951664|interpro:IPR036047|uniprotkb:Q96ME1(identity)|entrezgene/locuslink:80028(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:Qd5LwWpDzC3bxPRaGEVuqrZbxYk9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q8N1E6 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-6425532|ensembl:ENSP00000344855 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fxl14_human(display_long)|uniprotkb:FBXL14(gene name)|psi-mi:FBXL14(display_short)|uniprotkb:F-box and leucine-rich repeat protein 14(gene name synonym)|uniprotkb:FBL14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) ensembl:ENSG00000171823(gene)|ensembl:ENST00000339235(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|interpro:IPR036047|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_689654.1|uniprotkb:Q8N1E6(identity)|entrezgene/locuslink:144699(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:H8Gc4/0VTyLxX8UBNy6g0k5m1Qk9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q7Z6M2 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-8555452|intact:MINT-2831379|uniprotkb:Q86TR2|uniprotkb:Q6PIR2|uniprotkb:Q86YE0|ensembl:ENSP00000298097 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fbx33_human(display_long)|uniprotkb:FBXO33(gene name)|psi-mi:FBXO33(display_short)|uniprotkb:FBX33(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_976046.1|ensembl:ENSG00000165355(gene)|ensembl:ENST00000298097(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR032675|interpro:IPR036047|interpro:IPR039940|mint:Q7Z6M2|uniprotkb:Q7Z6M2(identity)|entrezgene/locuslink:254170(identity) psi-mi:"MI:0469"(intact) - function:"Substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Recognizes YBX1"|comment:mint figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:xghq3It9yrnTgJaIqLJgHK+Y4ME9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q9H469 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-6144096|uniprotkb:B1AKX9|uniprotkb:Q0D2Q3|uniprotkb:A1L4J8|uniprotkb:C9JWA4|uniprotkb:Q5JWA5|uniprotkb:Q49AL7|uniprotkb:B1AKY1|uniprotkb:B1AKY0|uniprotkb:B1AKX8|ensembl:ENSP00000358972 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fxl15_human(display_long)|uniprotkb:F-box only protein 37(gene name synonym)|uniprotkb:FBXO37(gene name synonym)|uniprotkb:FBXL15(gene name)|psi-mi:FBXL15(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_077302.3|refseq:XP_005270207.1|refseq:XP_005270208.1|refseq:XP_016872120.1|ensembl:ENSG00000107872(gene)|ensembl:ENST00000369956(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030282"(bone mineralization)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|interpro:IPR036047|reactome:R-HSA-8951664|reactome:R-HSA-983168|uniprotkb:Q9H469(identity)|entrezgene/locuslink:79176(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:mNR8gFDgo0wc6D/JUwPCw4sfy6I9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q9UK96 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-6425614|uniprotkb:Q08AL4|ensembl:ENSP00000403802|uniprotkb:Q5JRT8|uniprotkb:Q08AL3|uniprotkb:Q9UKC3 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fbx10_human(display_long)|uniprotkb:FBXO10(gene name)|psi-mi:FBXO10(display_short)|uniprotkb:FBX10(gene name synonym)|uniprotkb:PRMT11(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:XP_006716817.1|interpro:IPR039448|reactome:R-HSA-8951664|reactome:R-HSA-983168|ensembl:ENSG00000147912(gene)|ensembl:ENST00000432825(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006626(Parallel beta-helix repeat)|interpro:IPR006633(Carbohydrate-binding and sugar hydrolysis)|interpro:IPR007742(Periplasmic copper-binding)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012334(Pectin lyase fold)|interpro:IPR022441|interpro:IPR036047|refseq:NP_036298.2|refseq:XP_016870108.1|uniprotkb:Q9UK96(identity)|entrezgene/locuslink:26267(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:R2VbEMuZv8wyx6t4nfg1wqvqm4E9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q9UK97 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-2869927|uniprotkb:O75986|uniprotkb:B3KMM6|uniprotkb:A6NFW3|uniprotkb:Q6PKH7|uniprotkb:Q9NT57|uniprotkb:Q9Y593|uniprotkb:Q59EH8|ensembl:ENSP00000244426 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fbx9_human(display_long)|uniprotkb:FBXO9(gene name)|psi-mi:FBXO9(display_short)|uniprotkb:FBX9(gene name synonym)|uniprotkb:VCIA1(gene name synonym)|uniprotkb:Cross-immune reaction antigen 1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-57(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_036479.1|refseq:NP_258441.1|refseq:NP_258442.2|refseq:XP_005249052.1|refseq:XP_005249053.1|dip:DIP-60458N|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR036047|interpro:IPR036181|reactome:R-HSA-8951664|reactome:R-HSA-983168|ensembl:ENSG00000112146(gene)|ensembl:ENST00000244426(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032006"(regulation of TOR signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045444"(fat cell differentiation)|uniprotkb:Q9UK97(identity)|entrezgene/locuslink:26268(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:K1Zed3vHhHThzqy/vwhXIpZAAcE9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:P28066 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-355475|uniprotkb:B4E2V4|uniprotkb:Q6IBF7|uniprotkb:Q3T1C1|uniprotkb:B2R8F6|ensembl:ENSP00000271308 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:psa5_human(display_long)|uniprotkb:PSMA5(gene name)|psi-mi:PSMA5(display_short)|uniprotkb:Proteasome zeta chain(gene name synonym)|uniprotkb:Macropain zeta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex zeta chain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_001186701.1|refseq:NP_001186702.1|refseq:NP_001186703.1|refseq:NP_002781.2|ensembl:ENSG00000143106(gene)|ensembl:ENST00000271308(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR033812|mint:P28066|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEY|rcsb pdb:5LEX|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-29368N|uniprotkb:P28066(identity)|entrezgene/locuslink:5686(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:bfMG3npzVetUH1tahr2MAI4R+3g9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q9H4M3 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-2322644|uniprotkb:Q5TGX2|uniprotkb:Q5TGX4|uniprotkb:Q5TGX5|uniprotkb:Q68DJ9|uniprotkb:Q8WWY2|uniprotkb:B3KNZ2|uniprotkb:B7Z743|ensembl:ENSP00000251547|ensembl:ENSP00000365961 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fbx44_human(display_long)|uniprotkb:FBXO44(gene name)|psi-mi:FBXO44(display_short)|uniprotkb:FBG3(gene name synonym)|uniprotkb:FBX30(gene name synonym)|uniprotkb:FBX44(gene name synonym)|uniprotkb:FBX6A(gene name synonym)|uniprotkb:FBXO6A(gene name synonym)|uniprotkb:F-box/G-domain protein 3(gene name synonym)|uniprotkb:F-box protein FBX30(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_001291720.1|refseq:NP_001291719.1|refseq:XP_006711108.1|refseq:NP_001014765.1|refseq:NP_149438.2|refseq:NP_904319.1|refseq:NP_904320.1|refseq:XP_016858332.1|refseq:XP_016858333.1|ensembl:ENSG00000132879(gene)|ensembl:ENST00000251547(transcript)|ensembl:ENST00000376770(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR007397(F-box associated region)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036047|interpro:IPR039752|rcsb pdb:3WSO|rcsb pdb:5B4N|reactome:R-HSA-8951664|reactome:R-HSA-983168|uniprotkb:Q9H4M3(identity)|entrezgene/locuslink:93611(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:4pBdxSUZxIgZKD5rZXETdYIJ5UU9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:P28072 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-359288|uniprotkb:Q96J55|ensembl:ENSP00000270586 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:psb6_human(display_long)|uniprotkb:PSMB6(gene name)|psi-mi:PSMB6(display_short)|uniprotkb:LMPY(gene name synonym)|uniprotkb:Proteasome delta chain(gene name synonym)|uniprotkb:Macropain delta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex delta chain(gene name synonym)|uniprotkb:Proteasome subunit Y(gene name synonym)|uniprotkb:Y(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_002789.1|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035140|mint:P28072|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|go:"GO:0005737"(cytoplasm)|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000142507(gene)|ensembl:ENST00000270586(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-33847N|uniprotkb:P28072(identity)|entrezgene/locuslink:5694(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:4LRxYA6/tM2hsc96iP29c5J7ew49606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q6P3S6 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-2506081|ensembl:ENSP00000364742|uniprotkb:B3KP30|uniprotkb:Q5TEU8|uniprotkb:Q86XI0|uniprotkb:Q8N3N4|uniprotkb:Q8N5F8|uniprotkb:Q9BRM0|uniprotkb:Q9P2L4 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fbx42_human(display_long)|uniprotkb:FBXO42(gene name)|psi-mi:FBXO42(display_short)|uniprotkb:FBX42(gene name synonym)|uniprotkb:JFK(gene name synonym)|uniprotkb:KIAA1332(gene name synonym)|uniprotkb:Just one F-box and Kelch domain-containing protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) ensembl:ENSG00000037637(gene)|ensembl:ENST00000375592(transcript)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR036047|refseq:NP_061867.1|refseq:XP_006710761.1|uniprotkb:Q6P3S6(identity)|entrezgene/locuslink:54455(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:agCUwHKc4LmiE/1IrJsxJQNgUVo9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:P49720 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-603340|uniprotkb:P31147|uniprotkb:Q0P6J7|uniprotkb:Q96E27|ensembl:ENSP00000483688|ensembl:ENSP00000483956 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:psb3_human(display_long)|uniprotkb:PSMB3(gene name)|psi-mi:PSMB3(display_short)|uniprotkb:Proteasome theta chain(gene name synonym)|uniprotkb:Proteasome chain 13(gene name synonym)|uniprotkb:Proteasome component C10-II(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_002786.2|dip:DIP-33846N|ensembl:ENSG00000275903(gene)|ensembl:ENSG00000277791(gene)|ensembl:ENST00000619426(transcript)|ensembl:ENST00000619951(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR033811|mint:P49720|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|uniprotkb:P49720(identity)|entrezgene/locuslink:5691(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:H4UDdXV1BaXHp6mEPafNy+Iv8389606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q6W2J9 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N|uniprotkb:Q6W2J9(identity)|entrezgene/locuslink:54880(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q86XK2 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-1047804|uniprotkb:Q9H9L1|uniprotkb:Q9NR14|uniprotkb:Q9UFK1|uniprotkb:Q52ZP1|uniprotkb:Q53EP7|uniprotkb:Q8IXG3|uniprotkb:Q96E90|uniprotkb:Q9H6V8|uniprotkb:Q9UHI1|uniprotkb:Q9UKC2|uniprotkb:Q53RT5|uniprotkb:A1L491|ensembl:ENSP00000384823 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fbx11_human(display_long)|uniprotkb:Vitiligo-associated protein 1(gene name synonym)|uniprotkb:FBXO11(gene name)|psi-mi:FBXO11(display_short)|uniprotkb:FBX11(gene name synonym)|uniprotkb:VIT1(gene name synonym)|uniprotkb:PRMT9(gene name synonym)|uniprotkb:Protein arginine N-methyltransferase 9(gene name synonym)|uniprotkb:UG063H01(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_001177203.1|refseq:XP_016860506.1|refseq:NP_079409.3|refseq:XP_005264629.1|dip:DIP-35680N|ensembl:ENSG00000138081(gene)|ensembl:ENST00000403359(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR006626(Parallel beta-helix repeat)|interpro:IPR006633(Carbohydrate-binding and sugar hydrolysis)|interpro:IPR007742(Periplasmic copper-binding)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012334(Pectin lyase fold)|interpro:IPR022441|interpro:IPR029799|interpro:IPR036047|interpro:IPR039448|rcsb pdb:5VMD|reactome:R-HSA-8951664|reactome:R-HSA-983168|uniprotkb:Q86XK2(identity)|entrezgene/locuslink:80204(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:7tSKElIYe8osUxG4NtKI0lWkLak9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:O75592 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-1043774|uniprotkb:Q5JSX8|uniprotkb:Q5VZN6|uniprotkb:Q6PIB6|uniprotkb:Q9UQ11|uniprotkb:Q9Y6E4|uniprotkb:A6NJC6|ensembl:ENSP00000444596 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:mycb2_human(display_long)|uniprotkb:MYCBP2(gene name)|psi-mi:MYCBP2(display_short)|uniprotkb:KIAA0916(gene name synonym)|uniprotkb:PAM(gene name synonym)|uniprotkb:Myc-binding protein 2(gene name synonym)|uniprotkb:Protein associated with Myc(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_055872.4|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902667"(regulation of axon guidance)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003646(Bacterial SH3-like region)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR012983(PHR)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR038648|mint:O75592|rcsb pdb:5O6C|rcsb pdb:6T7F|ensembl:ENSG00000005810(gene)|ensembl:ENST00000544440(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0021785"(branchiomotor neuron axon guidance)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0030424"(axon)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032880"(regulation of protein localization)|dip:DIP-28142N|uniprotkb:O75592(identity)|entrezgene/locuslink:23077(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:AR3FR/zd48HkVinEfdT17ItGkbU9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q8TB52 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-2556210|uniprotkb:Q9BXZ7|ensembl:ENSP00000237281 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fbx30_human(display_long)|uniprotkb:FBX30(gene name synonym)|uniprotkb:FBXO30(gene name)|psi-mi:FBXO30(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_115521.3|refseq:XP_011534479.1|ensembl:ENSG00000118496(gene)|ensembl:ENST00000237281(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR031890|interpro:IPR036047|interpro:IPR043013|rcsb pdb:2YRE|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_001335021.1|refseq:XP_016866842.1|uniprotkb:Q8TB52(identity)|entrezgene/locuslink:84085(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:ZSddVg47+VIHJBP2vthCSVlnZkQ9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q5XUX1 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-2322729|uniprotkb:B3KVP7|uniprotkb:Q9BT89|ensembl:ENSP00000376945 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fbxw9_human(display_long)|uniprotkb:FBXW9(gene name)|psi-mi:FBXW9(display_short)|uniprotkb:FBW9(gene name synonym)|uniprotkb:F-box and WD-40 domain-containing protein 9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_115677.2|ensembl:ENSG00000132004(gene)|ensembl:ENST00000393261(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0030687"(preribosome, large subunit precursor)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036047|interpro:IPR036322|reactome:R-HSA-390471|reactome:R-HSA-8951664|reactome:R-HSA-983168|uniprotkb:Q5XUX1(identity)|entrezgene/locuslink:84261(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:srCRaEUd/tjElP41q22zfIRLvCM9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q9Y2K7 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-765758|ensembl:ENSP00000432786|uniprotkb:Q49A21|uniprotkb:Q4G0M3|uniprotkb:Q69YY8|uniprotkb:Q9BVH5|uniprotkb:Q9H7H5|uniprotkb:Q9UK66|uniprotkb:D4QA03|uniprotkb:E9PIL6|uniprotkb:I3VM55 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:kdm2a_human(display_long)|uniprotkb:CXXC8(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1A(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 11(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 11(gene name synonym)|uniprotkb:F-box protein FBL7(gene name synonym)|uniprotkb:F-box protein Lilina(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 8(gene name synonym)|uniprotkb:KDM2A(gene name)|psi-mi:KDM2A(display_short)|uniprotkb:FBL7(gene name synonym)|uniprotkb:KIAA1004(gene name synonym)|uniprotkb:JHDM1A(gene name synonym)|uniprotkb:FBXL11(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1A(gene name synonym)|uniprotkb:FBL11(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) ensembl:ENSG00000173120(gene)|ensembl:ENST00000529006(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0032452"(histone demethylase activity)|refseq:NP_036440.1|refseq:XP_011543163.1|refseq:NP_001243334.1|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR032675|mint:Q9Y2K7|rcsb pdb:2YU1|rcsb pdb:2YU2|rcsb pdb:4BBQ|rcsb pdb:6BYH|rcsb pdb:6C16|reactome:R-HSA-3214842|interpro:IPR041070|dip:DIP-34596N|uniprotkb:Q9Y2K7(identity)|entrezgene/locuslink:22992(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:FWcxfQykne+IrmtpDxZ218sEURc9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q9Y297 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-307461|uniprotkb:Q9Y213|uniprotkb:B5MD49|uniprotkb:Q5W142|ensembl:ENSP00000359206|uniprotkb:Q5W141 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fbw1a_human(display_long)|uniprotkb:BTRC(gene name)|psi-mi:BTRC(display_short)|uniprotkb:BTRCP(gene name synonym)|uniprotkb:FBW1A(gene name synonym)|uniprotkb:FBXW1A(gene name synonym)|uniprotkb:F-box and WD repeats protein beta-TrCP(gene name synonym)|uniprotkb:E3RSIkappaB(gene name synonym)|uniprotkb:pIkappaBalpha-E3 receptor subunit(gene name synonym)|uniprotkb:Epididymis tissue protein Li 2a(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_003930.1|refseq:NP_378663.1|ensembl:ENSG00000166167(gene)|ensembl:ENST00000370187(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016874"(ligase activity)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031648"(protein destabilization)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|interpro:IPR021977|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR036047|interpro:IPR036322|mint:Q9Y297|rcsb pdb:1P22|rcsb pdb:2P64|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|go:"GO:0046983"(protein dimerization activity)|rcsb pdb:6TTU|reactome:R-HSA-1169091|reactome:R-HSA-1170546|go:"GO:0048511"(rhythmic process)|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-195253|reactome:R-HSA-202424|go:"GO:0051726"(regulation of cell cycle)|reactome:R-HSA-2565942|reactome:R-HSA-2871837|reactome:R-HSA-3769402|reactome:R-HSA-400253|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-983168|dip:DIP-31607N|uniprotkb:Q9Y297(identity)|entrezgene/locuslink:8945(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:9/bXDY6YvJWvP6iMSgOPT9CNGAE9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q9ULD2 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-2818124|uniprotkb:A8K135|uniprotkb:Q9H7T2|uniprotkb:Q6PK49|uniprotkb:Q659F4|uniprotkb:B3KWJ9|uniprotkb:B9EGA1|uniprotkb:Q63HJ6|uniprotkb:Q8WTT9|uniprotkb:Q8N4M6|uniprotkb:Q6URW7|uniprotkb:B2RBJ6|uniprotkb:D3DSP8|uniprotkb:B4DH03|ensembl:ENSP00000262102 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:mtus1_human(display_long)|uniprotkb:MTUS1(gene name)|psi-mi:MTUS1(display_short)|uniprotkb:ATBP(gene name synonym)|uniprotkb:ATIP(gene name synonym)|uniprotkb:GK1(gene name synonym)|uniprotkb:KIAA1288(gene name synonym)|uniprotkb:MTSG1(gene name synonym)|uniprotkb:AT2 receptor-binding protein(gene name synonym)|uniprotkb:Angiotensin-II type 2 receptor-interacting protein(gene name synonym)|uniprotkb:Mitochondrial tumor suppressor 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_001001924.1|refseq:NP_001001925.1|refseq:NP_001001931.1|refseq:NP_001159865.1|refseq:NP_065800.1|refseq:NP_001317399.1|refseq:XP_016869189.1|refseq:XP_016869190.1|refseq:XP_016869191.1|ensembl:ENSG00000129422(gene)|ensembl:ENST00000262102(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008017"(microtubule binding)|go:"GO:0010758"(regulation of macrophage chemotaxis)|go:"GO:0015630"(microtubule cytoskeleton)|interpro:IPR029786|refseq:XP_005273636.1|refseq:XP_005273639.1|uniprotkb:Q9ULD2(identity)|entrezgene/locuslink:57509(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:48081802hEyRtGe+P2jOMZG0QWs9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:P20618 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-372273|uniprotkb:Q9BWA8|ensembl:ENSP00000262193|uniprotkb:B5BU76 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:psb1_human(display_long)|uniprotkb:PSMB1(gene name)|psi-mi:PSMB1(display_short)|uniprotkb:PSC5(gene name synonym)|uniprotkb:Proteasome component C5(gene name synonym)|uniprotkb:Macropain subunit C5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C5(gene name synonym)|uniprotkb:Proteasome gamma chain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) ensembl:ENSG00000008018(gene)|ensembl:ENST00000262193(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|mint:P20618|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|refseq:NP_002784.1|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M2B|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5LF1|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4608870|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-983168|reactome:R-HSA-9604323|dip:DIP-31193N|uniprotkb:P20618(identity)|entrezgene/locuslink:5689(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:DfIS480BUnqbXus9/KoojdkWgw09606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q8NFZ0 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-724767|uniprotkb:Q96K67|uniprotkb:Q96SW7|uniprotkb:Q5JVB1|uniprotkb:Q7Z4Q6|uniprotkb:Q7Z4R0|uniprotkb:Q8N1P5|uniprotkb:Q8N586|uniprotkb:Q96E82|uniprotkb:Q9UFB2|uniprotkb:Q5JVB0|ensembl:ENSP00000355415 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fbh1_human(display_long)|uniprotkb:FBH1(gene name)|psi-mi:FBH1(display_short)|uniprotkb:F-box only protein 18(gene name synonym)|uniprotkb:FBX18(gene name synonym)|uniprotkb:FBXO18(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_116196.3|refseq:NP_835363.1|ensembl:ENSG00000134452(gene)|ensembl:ENST00000362091(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000725"(recombinational repair)|go:"GO:0000737"(DNA catabolic process, endonucleolytic)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0048478"(replication fork protection)|go:"GO:0072429"(response to intra-S DNA damage checkpoint signaling)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|interpro:IPR000212(DNA helicase, UvrD/REP type)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR014017(DNA helicase, UvrD-like, C terminal)|interpro:IPR027417|interpro:IPR036047|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008219"(cell death)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031297"(replication fork processing)|go:"GO:0035562"(negative regulation of chromatin binding)|refseq:NP_001245381.1|refseq:NP_001245382.1|refseq:XP_011518050.1|uniprotkb:Q8NFZ0(identity)|entrezgene/locuslink:84893(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:gHFAJ/6l2s69lfhpp3Uo9/V7VZA9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q6PIJ6 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-2513135|ensembl:ENSP00000342023|uniprotkb:Q9HC40|uniprotkb:Q86VN3|uniprotkb:Q7Z2U0|uniprotkb:Q9H837|uniprotkb:Q9BXY6|uniprotkb:Q6PK72 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fbx38_human(display_long)|uniprotkb:FBXO38(gene name)|psi-mi:FBXO38(display_short)|uniprotkb:SP329(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR036047|interpro:IPR042354|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000145868(gene)|ensembl:ENST00000340253(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002842"(positive regulation of T cell mediated immune response to tumor cell)|refseq:NP_110420.3|refseq:NP_001258652.1|refseq:XP_005268570.1|uniprotkb:Q6PIJ6(identity)|entrezgene/locuslink:81545(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:/j2W7mAL7RdWukKthtgCaX3cV3k9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q5H9F3 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-8833946|uniprotkb:Q5H9F4|uniprotkb:Q9Y528|uniprotkb:Q8TEN3|uniprotkb:B5MDQ8|uniprotkb:Q6ZVE0|uniprotkb:Q5H9F2|ensembl:ENSP00000218147|ensembl:ENSP00000437775 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:bcorl_human(display_long)|uniprotkb:BCORL1(gene name)|psi-mi:BCORL1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) ensembl:ENSP00000218147|ensembl:ENSP00000437775|refseq:NP_068765.3|dip:DIP-60148N|ensembl:ENSG00000085185(gene)|ensembl:ENST00000218147(transcript)|ensembl:ENST00000540052(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q5H9F3|rcsb pdb:4HPM|rcsb pdb:5JH5|uniprotkb:Q5H9F3(identity)|entrezgene/locuslink:63035(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:uQdpjjO3QnnX19nR1Ky76HjCdhw9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:P25787 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-603262|uniprotkb:Q9BU45|ensembl:ENSP00000223321|intact:EBI-1237095|uniprotkb:Q6ICS6 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:psa2_human(display_long)|uniprotkb:PSMA2(gene name)|psi-mi:PSMA2(display_short)|uniprotkb:PSC3(gene name synonym)|uniprotkb:Proteasome component C3(gene name synonym)|uniprotkb:Macropain subunit C3(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C3(gene name synonym)|uniprotkb:HC3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) mint:P25787|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|ensembl:ENSG00000106588(gene)|ensembl:ENST00000223321(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0009615"(response to virus)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|refseq:NP_002778.1|dip:DIP-29364N|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|uniprotkb:P25787(identity)|entrezgene/locuslink:5683(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:COncAMXXqT+zAHA/nK+7dweRg9A9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q14155 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-717515|uniprotkb:B1ALK6|uniprotkb:B1ALK8|uniprotkb:Q3LIA4|uniprotkb:Q5W9H0|uniprotkb:Q6P9G3|uniprotkb:Q6PII2|uniprotkb:Q86W63|uniprotkb:Q8N3M1|ensembl:ENSP00000364893 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:arhg7_human(display_long)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:COOL-1(gene name synonym)|uniprotkb:p85(gene name synonym)|uniprotkb:Nbla10314(orf name)|uniprotkb:ARHGEF7(gene name)|psi-mi:ARHGEF7(display_short)|uniprotkb:COOL1(gene name synonym)|uniprotkb:KIAA0142(gene name synonym)|uniprotkb:P85SPR(gene name synonym)|uniprotkb:PAK3BP(gene name synonym)|uniprotkb:PIXB(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_001307782.1|refseq:NP_663788.1|refseq:NP_001106983.1|refseq:NP_001106984.1|refseq:NP_001106985.1|refseq:NP_001307780.1|refseq:NP_001307783.1|refseq:NP_001317526.1|refseq:NP_001317527.1|ensembl:ENSG00000102606(gene)|ensembl:ENST00000375741(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0005925"(focal adhesion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043005"(neuron projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0098794"(postsynapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1904424"(regulation of GTP binding)|go:"GO:1905833"(negative regulation of microtubule nucleation)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035789|interpro:IPR035899|interpro:IPR036028|interpro:IPR036872|mint:Q14155|rcsb pdb:1BY1|rcsb pdb:1ZSG|rcsb pdb:2L3G|rcsb pdb:5SXP|reactome:R-HSA-182971|reactome:R-HSA-193648|reactome:R-HSA-3928664|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9619229|dip:DIP-40794N|refseq:NP_003890.1|refseq:XP_016876313.1|refseq:XP_016876314.1|uniprotkb:Q14155(identity)|entrezgene/locuslink:8874(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:0I59YglGXcYP7fFKIAWM6uCZY8Q9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:P49721 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-359335|uniprotkb:P31145|uniprotkb:Q9BWZ9|uniprotkb:D3DPS0|ensembl:ENSP00000362334 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:psb2_human(display_long)|uniprotkb:PSMB2(gene name)|psi-mi:PSMB2(display_short)|uniprotkb:Multicatalytic endopeptidase complex subunit C7-I(gene name synonym)|uniprotkb:Proteasome component C7-I(gene name synonym)|uniprotkb:Macropain subunit C7-I(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_002785.1|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5GJR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-5689603|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000126067(gene)|ensembl:ENST00000373237(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035206|mint:P49721|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|dip:DIP-33848N|uniprotkb:P49721(identity)|entrezgene/locuslink:5690(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:PvXrk6RLayQ1zqmavn1cONfA9/A9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:P57775 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-2372268|uniprotkb:Q5SVS1|uniprotkb:Q96IM6|ensembl:ENSP00000499522 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fbxw4_human(display_long)|uniprotkb:FBXW4(gene name)|psi-mi:FBXW4(display_short)|uniprotkb:FBW4(gene name synonym)|uniprotkb:SHFM3(gene name synonym)|uniprotkb:F-box and WD-40 domain-containing protein 4(gene name synonym)|uniprotkb:Dactylin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_071322.1|dip:DIP-41762N|ensembl:ENSG00000107829(gene)|ensembl:ENST00000664783(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036047|interpro:IPR036322|reactome:R-HSA-390471|reactome:R-HSA-8951664|reactome:R-HSA-983168|uniprotkb:P57775(identity)|entrezgene/locuslink:6468(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:WxbTe9OtzPFHBHn0qQ+vWIFqjuE9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q8N3Y1 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-914770|uniprotkb:Q9UK95|ensembl:ENSP00000498999 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fbxw8_human(display_long)|uniprotkb:F-box and WD-40 domain-containing protein 8(gene name synonym)|uniprotkb:F-box only protein 29(gene name synonym)|uniprotkb:FBXW8(gene name)|psi-mi:FBXW8(display_short)|uniprotkb:FBW6(gene name synonym)|uniprotkb:FBW8(gene name synonym)|uniprotkb:FBX29(gene name synonym)|uniprotkb:FBXO29(gene name synonym)|uniprotkb:FBXW6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_036306.1|refseq:NP_699179.2|dip:DIP-37970N|ensembl:ENSG00000174989(gene)|ensembl:ENST00000652555(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007030"(Golgi organization)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0060712"(spongiotrophoblast layer development)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:1901485"(positive regulation of transcription factor catabolic process)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036047|mint:Q8N3Y1|reactome:R-HSA-8951664|reactome:R-HSA-983168|uniprotkb:Q8N3Y1(identity)|entrezgene/locuslink:26259(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:ZDA8PrhdPFz2guszLIhjtVhiXsE9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:P25786 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-359352|uniprotkb:Q9BRV9|uniprotkb:A8K400|uniprotkb:Q53YE8|ensembl:ENSP00000379676 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:psa1_human(display_long)|uniprotkb:PSMA1(gene name)|psi-mi:PSMA1(display_short)|uniprotkb:PROS30(gene name synonym)|uniprotkb:PSC2(gene name synonym)|uniprotkb:Proteasome component C2(gene name synonym)|uniprotkb:Macropain subunit C2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C2(gene name synonym)|uniprotkb:Proteasome nu chain(gene name synonym)|uniprotkb:30 kDa prosomal protein(gene name synonym)|uniprotkb:HC2(gene name synonym)|uniprotkb:NU(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_002777.1|refseq:NP_683877.1|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000129084(gene)|ensembl:ENST00000396394(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|mint:P25786|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|dip:DIP-29369N|uniprotkb:P25786(identity)|entrezgene/locuslink:5682(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:tAADzZ1G9E/0BBeS8vybNx97v7k9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q13616 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-359390|uniprotkb:O60719|uniprotkb:Q08AL6|uniprotkb:Q8IYW1|uniprotkb:D3DWG3|ensembl:ENSP00000326804|ensembl:ENSP00000387160|ensembl:ENSP00000473318|ensembl:ENSP00000499255|ensembl:ENSP00000499277|ensembl:ENSP00000499398 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:cul1_human(display_long)|uniprotkb:CUL1(gene name)|psi-mi:CUL1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_003583.2|rcsb pdb:6WCQ|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7B5R|rcsb pdb:7B5S|reactome:R-HSA-1169091|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|refseq:XP_011514931.1|refseq:XP_011514932.1|refseq:XP_011514933.1|refseq:XP_011514934.1|ensembl:ENSG00000055130(gene)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|ensembl:ENST00000325222(transcript)|ensembl:ENST00000409469(transcript)|ensembl:ENST00000602748(transcript)|ensembl:ENST00000662716(transcript)|ensembl:ENST00000663044(transcript)|ensembl:ENST00000665936(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13616|rcsb pdb:1LDJ|rcsb pdb:1LDK|rcsb pdb:1U6G|rcsb pdb:3RTR|rcsb pdb:3TDU|rcsb pdb:3TDZ|rcsb pdb:4F52|rcsb pdb:4P5O|rcsb pdb:5V89|rcsb pdb:6TTU|refseq:XP_005250117.1|dip:DIP-17013N|uniprotkb:Q13616(identity)|entrezgene/locuslink:8454(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:OAZP+ifWW3eEnQKb937ww9s1fMQ9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q9UKT4 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-852298|uniprotkb:Q8WV29|uniprotkb:Q9UGC8|uniprotkb:B3KNX5|uniprotkb:Q5TF47|ensembl:ENSP00000229758 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fbx5_human(display_long)|uniprotkb:FBXO5(gene name)|psi-mi:FBXO5(display_short)|uniprotkb:EMI1(gene name synonym)|uniprotkb:FBX5(gene name synonym)|uniprotkb:Early mitotic inhibitor 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_001135994.1|refseq:NP_036309.1|dip:DIP-38023N|ensembl:ENSG00000112029(gene)|ensembl:ENST00000229758(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007057"(spindle assembly involved in female meiosis I)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0016050"(vesicle organization)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032876"(negative regulation of DNA endoreduplication)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045835"(negative regulation of meiotic nuclear division)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0070169"(positive regulation of biomineral tissue development)|go:"GO:0072687"(meiotic spindle)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1905322"(positive regulation of mesenchymal stem cell migration)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2001021"(negative regulation of response to DNA damage stimulus)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR044064|mint:Q9UKT4|rcsb pdb:2M6N|rcsb pdb:4UI9|reactome:R-HSA-174113|reactome:R-HSA-176408|reactome:R-HSA-176417|reactome:R-HSA-68881|reactome:R-HSA-69205|uniprotkb:Q9UKT4(identity)|entrezgene/locuslink:26271(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:6NU7FdV1cnJsK3TuNKMdirgBhVM9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q9UKT5 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-960409|ensembl:ENSP00000281623|uniprotkb:Q68CU8|uniprotkb:Q86VT8|uniprotkb:Q9UK98 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fbx4_human(display_long)|uniprotkb:FBXO4(gene name)|psi-mi:FBXO4(display_short)|uniprotkb:FBX4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) ensembl:ENSG00000151876(gene)|ensembl:ENST00000281623(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007568"(aging)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035726"(common myeloid progenitor cell proliferation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR027417|interpro:IPR036047|go:"GO:0019005"(SCF ubiquitin ligase complex)|rcsb pdb:3L2O|rcsb pdb:3L82|reactome:R-HSA-390471|reactome:R-HSA-8951664|reactome:R-HSA-983168|interpro:IPR039588|refseq:NP_036308.1|refseq:NP_277019.1|uniprotkb:Q9UKT5(identity)|entrezgene/locuslink:26272(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:tCM4jv7DF/Wujdm2j3i95oknxaE9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:P28074 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-357828|uniprotkb:Q16242|uniprotkb:Q6PEW2|intact:EBI-1237472|uniprotkb:Q7Z3B5|uniprotkb:Q9TNN9|uniprotkb:B2R4N9|uniprotkb:D3DS43|uniprotkb:B4DUM9|uniprotkb:Q86T01|uniprotkb:E9PAV2|ensembl:ENSP00000355325 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:psb5_human(display_long)|uniprotkb:PSMB5(gene name)|psi-mi:PSMB5(display_short)|uniprotkb:LMPX(gene name synonym)|uniprotkb:Proteasome epsilon chain(gene name synonym)|uniprotkb:Macropain epsilon chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex epsilon chain(gene name synonym)|uniprotkb:Proteasome subunit X(gene name synonym)|uniprotkb:Proteasome chain 6(gene name synonym)|uniprotkb:Proteasome subunit MB1(gene name synonym)|uniprotkb:MB1(gene name synonym)|uniprotkb:X(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_001124197.1|refseq:NP_001138404.1|refseq:NP_002788.1|dip:DIP-27540N|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5610785|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|ensembl:ENSG00000100804(gene)|ensembl:ENST00000361611(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006508"(proteolysis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008233"(peptidase activity)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|mint:P28074|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|uniprotkb:P28074(identity)|entrezgene/locuslink:5693(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:73T59wniLri/465F3BhBvwL1/LM9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q9HC35 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-717876|uniprotkb:Q3SWW0|uniprotkb:Q53R29|uniprotkb:Q53TW8|uniprotkb:Q6PJ45|uniprotkb:Q9NV40|uniprotkb:B2RTW7|uniprotkb:B2RBK3|uniprotkb:A6H8Y6|uniprotkb:B5MCW9|intact:EBI-28969987|ensembl:ENSP00000320663 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:emal4_human(display_long)|uniprotkb:Restrictedly overexpressed proliferation-associated protein(gene name synonym)|uniprotkb:Ropp 120(gene name synonym)|uniprotkb:EML4(gene name)|psi-mi:EML4(display_short)|uniprotkb:C2orf2(gene name synonym)|uniprotkb:EMAPL4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_061936.2|ensembl:ENSP00000320663|ensembl:ENST00000402711|ensembl:ENSP00000385059|refseq:NP_001138548.1|ensembl:ENSG00000143924(gene)|ensembl:ENST00000318522(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008017"(microtubule binding)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|interpro:IPR001680(WD40 repeat)|interpro:IPR005108(HELP)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:4CGC|reactome:R-HSA-9648025|uniprotkb:Q9HC35(identity)|entrezgene/locuslink:27436(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:Uil30Xzo4QqT/8hfUP7TJbuCG3o9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q15052 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-1642523|uniprotkb:A6NMW9|uniprotkb:A8K6S7|uniprotkb:Q15396|uniprotkb:Q5JQ66|uniprotkb:Q7Z3W1|uniprotkb:Q86XH0|uniprotkb:B1AL37|ensembl:ENSP00000250617 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:arhg6_human(display_long)|uniprotkb:ARHGEF6(gene name)|psi-mi:ARHGEF6(display_short)|uniprotkb:COOL2(gene name synonym)|uniprotkb:KIAA0006(gene name synonym)|uniprotkb:PIXA(gene name synonym)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 6(gene name synonym)|uniprotkb:PAK-interacting exchange factor alpha(gene name synonym)|uniprotkb:Alpha-Pix(gene name synonym)|uniprotkb:COOL-2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_001293106.1|refseq:NP_004831.1|dip:DIP-42694N|ensembl:ENSG00000129675(gene)|ensembl:ENST00000250617(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007254"(JNK cascade)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003096(SM22/calponin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR032409|interpro:IPR035788|interpro:IPR035899|interpro:IPR036028|interpro:IPR036872|mint:Q15052|rcsb pdb:1UJY|rcsb pdb:1WYR|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-446388|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013420|uniprotkb:Q15052(identity)|entrezgene/locuslink:9459(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:i0wD4z4cHFbao49tTRqN2m9Qw7w9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q9NRD1 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-3938499|uniprotkb:B1AK42|uniprotkb:Q9UKT3|uniprotkb:B2RC88|intact:EBI-28977383|ensembl:ENSP00000365944 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fbx6_human(display_long)|uniprotkb:FBXO6(gene name)|psi-mi:FBXO6(display_short)|uniprotkb:FBG2(gene name synonym)|uniprotkb:FBS2(gene name synonym)|uniprotkb:FBX6(gene name synonym)|uniprotkb:F-box protein that recognizes sugar chains 2(gene name synonym)|uniprotkb:F-box/G-domain protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) ensembl:ENSP00000365944|refseq:XP_011539534.1|ensembl:ENSG00000116663(gene)|ensembl:ENST00000376753(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006508"(proteolysis)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR007397(F-box associated region)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036047|interpro:IPR039752|reactome:R-HSA-390471|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_060908.1|refseq:XP_005263505.1|refseq:XP_005263506.1|refseq:XP_005263508.1|refseq:XP_006710634.1|refseq:XP_016856496.1|uniprotkb:Q9NRD1(identity)|entrezgene/locuslink:26270(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:I4V9ZtDHo7W175sn3w8efv1DhsE9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q9UF56 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-8835653|uniprotkb:A1A4E3|ensembl:ENSP00000437464 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fxl17_human(display_long)|uniprotkb:F-box and leucine-rich repeat protein 17(gene name synonym)|uniprotkb:F-box only protein 13(gene name synonym)|uniprotkb:FBL17(gene name synonym)|uniprotkb:FBX13(gene name synonym)|uniprotkb:FBXO13(gene name synonym)|uniprotkb:FBXL17(gene name)|psi-mi:FBXL17(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_001156787.2|ensembl:ENSG00000145743(gene)|ensembl:ENST00000542267(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0007399"(nervous system development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0014033"(neural crest cell differentiation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|interpro:IPR036047|rcsb pdb:6W66|rcsb pdb:6WCQ|reactome:R-HSA-9708530|uniprotkb:Q9UF56(identity)|entrezgene/locuslink:64839(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:yhKhGdbxOtSGsziIyUydFyfUUP49606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q9NXK8 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-719790|uniprotkb:Q9H5K4|uniprotkb:B3KSJ8|ensembl:ENSP00000247977 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fxl12_human(display_long)|uniprotkb:F-box and leucine-rich repeat protein 12(gene name synonym)|uniprotkb:F-box protein FBL12(gene name synonym)|uniprotkb:FBXL12(gene name)|psi-mi:FBXL12(display_short)|uniprotkb:FBL12(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_060173.1|refseq:NP_001303865.1|refseq:NP_001303866.1|refseq:NP_001303867.1|refseq:NP_001303868.1|refseq:NP_001303869.1|refseq:NP_001303870.1|refseq:NP_001303871.1|ensembl:ENSG00000127452(gene)|ensembl:ENST00000247977(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR032675|interpro:IPR036047|mint:Q9NXK8|reactome:R-HSA-8951664|reactome:R-HSA-983168|uniprotkb:Q9NXK8(identity)|entrezgene/locuslink:54850(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:b+3vZLMbZvEww+hdTa3YnLkPiC49606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:P61024 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-456371|uniprotkb:P33551|ensembl:ENSP00000311083 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:cks1_human(display_long)|uniprotkb:PNAS-16(orf name)|uniprotkb:PNAS-143(orf name)|uniprotkb:CKS1B(gene name)|psi-mi:CKS1B(display_short)|uniprotkb:CKS1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_001817.1|dip:DIP-102N|rcsb pdb:4YC6|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-187577|reactome:R-HSA-69231|ensembl:ENSG00000173207(gene)|ensembl:ENST00000308987(transcript)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0042393"(histone binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|interpro:IPR000789(Cyclin-dependent kinase, regulatory subunit)|interpro:IPR036858|mint:P61024|rcsb pdb:1BUH|rcsb pdb:1DKS|rcsb pdb:1DKT|rcsb pdb:2ASS|rcsb pdb:2AST|uniprotkb:P61024(identity)|entrezgene/locuslink:1163(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:ANoFqi0sBqFKOAyhcMhTWA9kghY9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q8WUF8 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-2556079|uniprotkb:Q9H0U8|uniprotkb:B2R7C6|uniprotkb:B4DJ14|uniprotkb:B4DLG5|ensembl:ENSP00000379294 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:f172a_human(display_long)|uniprotkb:C5orf21(gene name synonym)|uniprotkb:FAM172A(gene name)|psi-mi:FAM172A(display_short)|uniprotkb:Protein FAM172A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_001156889.1|refseq:NP_001156890.1|refseq:NP_114431.2|refseq:XP_011541974.1|refseq:XP_006714780.1|refseq:XP_016865444.1|refseq:XP_016865445.1|ensembl:ENSG00000113391(gene)|ensembl:ENST00000395965(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0014032"(neural crest cell development)|go:"GO:0031048"(heterochromatin assembly by small RNA)|interpro:IPR029058|interpro:IPR039929|uniprotkb:Q8WUF8(identity)|entrezgene/locuslink:83989(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:6bDzV1sfpO3EGQ74VuWXY9g5p5A9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q969U6 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-741068|ensembl:ENSP00000313034|uniprotkb:Q5SPZ8|uniprotkb:Q5SPZ9|uniprotkb:Q5SQ02|uniprotkb:Q5SQ03|uniprotkb:Q5SQ04|uniprotkb:Q8WY79|uniprotkb:Q96GJ6|uniprotkb:Q9BSU8|uniprotkb:Q9H6A8|uniprotkb:Q9HBQ6|uniprotkb:Q9NSZ3|uniprotkb:B2RDZ6|uniprotkb:Q59ET5|uniprotkb:Q5SQ00 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fbxw5_human(display_long)|uniprotkb:F-box and WD-40 domain-containing protein 5(gene name synonym)|uniprotkb:FBXW5(gene name)|psi-mi:FBXW5(display_short)|uniprotkb:FBW5(gene name synonym)|uniprotkb:PP3971(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) ensembl:ENSG00000159069(gene)|ensembl:ENST00000325285(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036047|interpro:IPR036322|interpro:IPR042508|mint:Q969U6|reactome:R-HSA-390471|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_061871.1|dip:DIP-37971N|uniprotkb:Q969U6(identity)|entrezgene/locuslink:54461(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:5K7xqxsvQuvEqWljgZXi/I+aWxE9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:O94952 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-311435|uniprotkb:Q5BJG0|uniprotkb:Q9H087|uniprotkb:B3KMF0|ensembl:ENSP00000328187 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fbx21_human(display_long)|uniprotkb:FBXO21(gene name)|psi-mi:FBXO21(display_short)|uniprotkb:FBX21(gene name synonym)|uniprotkb:KIAA0875(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_055817.1|refseq:NP_296373.1|ensembl:ENSG00000135108(gene)|ensembl:ENST00000330622(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|interpro:IPR011722(Hemimethylated DNA-binding region)|interpro:IPR032698|interpro:IPR036047|interpro:IPR036623|reactome:R-HSA-8951664|reactome:R-HSA-983168|uniprotkb:O94952(identity)|entrezgene/locuslink:23014(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:FJoicuj4hHZOzbtVJcwCnUOqC3c9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q8N531 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-2322696|uniprotkb:Q53G43|uniprotkb:Q9H5W9|uniprotkb:Q9UKC7|ensembl:ENSP00000330098|ensembl:ENSP00000403873 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fbxl6_human(display_long)|uniprotkb:FBXL6(gene name)|psi-mi:FBXL6(display_short)|uniprotkb:FBL6(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 6(gene name synonym)|uniprotkb:F-box protein FBL6(gene name synonym)|uniprotkb:FBL6A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_036294.2|refseq:NP_078831.4|interpro:IPR036047|ensembl:ENSG00000182325(gene)|ensembl:ENST00000331890(transcript)|ensembl:ENST00000455319(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|uniprotkb:Q8N531(identity)|entrezgene/locuslink:26233(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:7TZnViSojOOkvwbJcW+shi9hQNA9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q9UKA2 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-2869903|uniprotkb:Q9UJU0|uniprotkb:O95919|uniprotkb:Q5BJH0|uniprotkb:E1P530|uniprotkb:B2R7Q5|ensembl:ENSP00000229971|ensembl:ENSP00000358247 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fbxl4_human(display_long)|uniprotkb:FBXL4(gene name)|psi-mi:FBXL4(display_short)|uniprotkb:FBL4(gene name synonym)|uniprotkb:FBL5(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 4(gene name synonym)|uniprotkb:F-box protein FBL4/FBL5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:XP_016866215.1|refseq:NP_036292.2|refseq:NP_001265645.1|ensembl:ENSG00000112234(gene)|ensembl:ENST00000229971(transcript)|ensembl:ENST00000369244(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|interpro:IPR036047|reactome:R-HSA-8951664|reactome:R-HSA-983168|uniprotkb:Q9UKA2(identity)|entrezgene/locuslink:26235(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:NxOhj1qXQhFlbTVmvCo5etF7Yd09606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:P60900 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-357793|uniprotkb:P34062|uniprotkb:Q6IB60|uniprotkb:B2R7J9|uniprotkb:B4DQR4|uniprotkb:B4DXJ9|ensembl:ENSP00000261479 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:psa6_human(display_long)|uniprotkb:PSMA6(gene name)|psi-mi:PSMA6(display_short)|uniprotkb:PROS27(gene name synonym)|uniprotkb:Proteasome iota chain(gene name synonym)|uniprotkb:Macropain iota chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex iota chain(gene name synonym)|uniprotkb:27 kDa prosomal protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_002782.1|refseq:NP_001269162.1|refseq:NP_001269163.1|refseq:XP_016876957.1|refseq:NP_001269161.1|ensembl:ENSG00000100902(gene)|ensembl:ENST00000261479(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0035639"(purine ribonucleoside triphosphate binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034642|mint:P60900|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-29367N|uniprotkb:P60900(identity)|entrezgene/locuslink:5687(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:F+Kwr6rnDS3jD53gBGHDIn7HV/89606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q99496 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|entrezgene/locuslink:6045(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q96PK6 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-954272|ensembl:ENSP00000311747|uniprotkb:O75932|uniprotkb:Q53GV1|uniprotkb:Q68DQ9|uniprotkb:Q96PK5|uniprotkb:B3KMN4|uniprotkb:Q2PYN1|uniprotkb:D6RGD8|uniprotkb:B0LM41|intact:EBI-16430855|intact:EBI-16472484 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:rbm14_human(display_long)|uniprotkb:RNA-binding motif protein 14(gene name synonym)|uniprotkb:RRM-containing coactivator activator/modulator(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein(gene name synonym)|uniprotkb:RBM14(gene name)|psi-mi:RBM14(display_short)|uniprotkb:SIP(gene name synonym)|uniprotkb:Paraspeckle protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) ensembl:ENSG00000239306(gene)|ensembl:ENST00000310137(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009725"(response to hormone)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034506|interpro:IPR034507|go:"GO:0098534"(centriole assembly)|interpro:IPR035979|mint:Q96PK6|rcsb pdb:2DNP|reactome:R-HSA-8941326|refseq:NP_001185765.1|refseq:NP_006319.1|ensembl:ENSP00000311747|ensembl:ENST00000393979|ensembl:ENSP00000377548|ensembl:ENST00000409738|ensembl:ENSP00000386995|refseq:NP_001185766.1|refseq:NP_001185774.1|dip:DIP-50126N|uniprotkb:Q96PK6(identity)|entrezgene/locuslink:10432(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:Q0UBl2qmfwQTPwUQ7ZDwGIMOYoA9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q9UKC9 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-724253|ensembl:ENSP00000417601|uniprotkb:Q6IAN3|uniprotkb:Q9Y3Y9|uniprotkb:Q9NVQ8|uniprotkb:Q9UK27|uniprotkb:Q9UKA5|uniprotkb:B4DQV0|uniprotkb:E9PD06 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fbxl2_human(display_long)|uniprotkb:F-box and leucine-rich repeat protein 2(gene name synonym)|uniprotkb:F-box protein FBL2/FBL3(gene name synonym)|uniprotkb:FBXL2(gene name)|psi-mi:FBXL2(display_short)|uniprotkb:FBL2(gene name synonym)|uniprotkb:FBL3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) ensembl:ENSG00000153558(gene)|ensembl:ENST00000484457(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006508"(proteolysis)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|interpro:IPR001611(Leucine-rich repeat)|refseq:NP_001165184.1|refseq:NP_036289.3|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|rcsb pdb:6O60|uniprotkb:Q9UKC9(identity)|entrezgene/locuslink:25827(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:BkHs0ftn8BdTq/UmoduZueg5C649606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:P25789 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-359310|uniprotkb:Q8TBD1|uniprotkb:Q53XP2|ensembl:ENSP00000044462|ensembl:ENSP00000453887|uniprotkb:D3DW86|uniprotkb:Q567Q5 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:psa4_human(display_long)|uniprotkb:PSMA4(gene name)|psi-mi:PSMA4(display_short)|uniprotkb:PSC9(gene name synonym)|uniprotkb:Proteasome component C9(gene name synonym)|uniprotkb:Macropain subunit C9(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C9(gene name synonym)|uniprotkb:Proteasome subunit L(gene name synonym)|uniprotkb:HC9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_001096137.1|refseq:NP_002780.1|rcsb pdb:6XMJ|reactome:R-HSA-2467813|reactome:R-HSA-2871837|rcsb pdb:7AWE|reactome:R-HSA-349425|reactome:R-HSA-1169091|reactome:R-HSA-350562|reactome:R-HSA-1234176|reactome:R-HSA-382556|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-450408|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-4641258|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5358346|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000041357(gene)|ensembl:ENST00000044462(transcript)|ensembl:ENST00000559082(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034647|mint:P25789|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|refseq:NP_001096138.1|refseq:NP_001317605.1|dip:DIP-29365N|uniprotkb:P25789(identity)|entrezgene/locuslink:5685(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:u+wKxvIa9JKb4Zu9K+tnY3d26tw9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:P0C2W1 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-2511355|ensembl:ENSP00000310332|uniprotkb:A6NF90|uniprotkb:D3DXB5 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fbsp1_human(display_long)|uniprotkb:FBXO45(gene name)|psi-mi:FBXO45(display_short)|uniprotkb:FBX45(gene name synonym)|uniprotkb:F-box only protein 45(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR035784|interpro:IPR036047|interpro:IPR043136|ensembl:ENSG00000174013(gene)|ensembl:ENST00000311630(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0021799"(cerebral cortex radially oriented cell migration)|go:"GO:0021800"(cerebral cortex tangential migration)|go:"GO:0021957"(corticospinal tract morphogenesis)|go:"GO:0021960"(anterior commissure morphogenesis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042995"(cell projection)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0060386"(synapse assembly involved in innervation)|go:"GO:0098978"(glutamatergic synapse)|refseq:NP_001099043.1|uniprotkb:P0C2W1(identity)|entrezgene/locuslink:200933(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:dr+dGdYmjZoA/fo7CyxhmLyWRLM9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q99436 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-603319|uniprotkb:Q96AG8|uniprotkb:Q9BWA7|uniprotkb:B4E0P1|uniprotkb:Q5TBG6|ensembl:ENSP00000259457 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:psb7_human(display_long)|uniprotkb:PSMB7(gene name)|psi-mi:PSMB7(display_short)|uniprotkb:Proteasome subunit Z(gene name synonym)|uniprotkb:Macropain chain Z(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain Z(gene name synonym)|uniprotkb:Z(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_002790.1|dip:DIP-33843N|ensembl:ENSG00000136930(gene)|ensembl:ENST00000259457(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016604"(nuclear body)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR024689|interpro:IPR029055|interpro:IPR035216|mint:Q99436|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|uniprotkb:Q99436(identity)|entrezgene/locuslink:5695(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:w880QftOor3RdaGvhCup7apz2OM9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q9UK99 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-2509901|uniprotkb:B3KY16|uniprotkb:D3DR05|uniprotkb:Q9H0V2|uniprotkb:Q86X90|uniprotkb:Q9NUX2|ensembl:ENSP00000265651 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fbx3_human(display_long)|uniprotkb:FBXO3(gene name)|psi-mi:FBXO3(display_short)|uniprotkb:FBX3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_036307.2|refseq:NP_208385.1|dip:DIP-53688N|ensembl:ENSG00000110429(gene)|ensembl:ENST00000265651(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR007474(ApaG)|interpro:IPR018958|interpro:IPR028388|interpro:IPR036047|interpro:IPR036767|interpro:IPR037883|rcsb pdb:5HDW|uniprotkb:Q9UK99(identity)|entrezgene/locuslink:26273(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:zQB8ig3s51tXN81NtMrou84Rv6I9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q96IG2 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-8835647|uniprotkb:Q38J52|uniprotkb:A8K729|ensembl:ENSP00000264658|ensembl:ENSP00000462271 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fxl20_human(display_long)|uniprotkb:F-box and leucine-rich repeat protein 20(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 2-like(gene name synonym)|uniprotkb:FBL2(gene name synonym)|uniprotkb:FBXL20(gene name)|psi-mi:FBXL20(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_001171835.1|refseq:NP_116264.2|ensembl:ENSG00000108306(gene)|ensembl:ENST00000264658(transcript)|ensembl:ENST00000583610(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0005829"(cytosol)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099575"(regulation of protein catabolic process at presynapse, modulating synaptic transmission)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|reactome:R-HSA-8951664|reactome:R-HSA-983168|uniprotkb:Q96IG2(identity)|entrezgene/locuslink:84961(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:ETNtMjWwCEbabOTm7Xf0UemzBIM9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:P28070 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-603350|uniprotkb:P31148|uniprotkb:Q5SZS5|uniprotkb:Q969L6|uniprotkb:B2R9L3|uniprotkb:Q6IBI4|ensembl:ENSP00000290541 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:psb4_human(display_long)|uniprotkb:PSMB4(gene name)|psi-mi:PSMB4(display_short)|uniprotkb:Macropain beta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex beta chain(gene name synonym)|uniprotkb:Proteasome chain 3(gene name synonym)|uniprotkb:26 kDa prosomal protein(gene name synonym)|uniprotkb:PROS26(gene name synonym)|uniprotkb:Proteasome beta chain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_002787.2|dip:DIP-33844N|ensembl:ENSG00000159377(gene)|ensembl:ENST00000290541(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR016295(Proteasome endopeptidase complex, beta subunit)|interpro:IPR023333|interpro:IPR029055|mint:P28070|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|uniprotkb:P28070(identity)|entrezgene/locuslink:5692(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:drR+ktPXQK9ep6hs7OYb5SmQnXU9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q9NVF7 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-740282|uniprotkb:O75070|ensembl:ENSP00000355827|uniprotkb:E9PEM8 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fbx28_human(display_long)|uniprotkb:FBXO28(gene name)|psi-mi:FBXO28(display_short)|uniprotkb:KIAA0483(gene name synonym)|uniprotkb:CENP-30(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_055991.1|ensembl:ENSG00000143756(gene)|ensembl:ENST00000366862(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000776"(kinetochore)|go:"GO:0042802"(identical protein binding)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR036047|interpro:IPR039719|refseq:NP_001129587.1|dip:DIP-56683N|uniprotkb:Q9NVF7(identity)|entrezgene/locuslink:23219(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:Iz7yI5ugv60KqYH7MAdBjXjw2vs9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q9BSM1 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5|uniprotkb:Q9BSM1(identity)|entrezgene/locuslink:84759(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:P25788 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-348380|ensembl:ENSP00000216455|uniprotkb:Q86U83|uniprotkb:Q8N1D8|uniprotkb:Q9BS70|uniprotkb:B2RCK6 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:psa3_human(display_long)|uniprotkb:PSMA3(gene name)|psi-mi:PSMA3(display_short)|uniprotkb:PSC8(gene name synonym)|uniprotkb:Proteasome component C8(gene name synonym)|uniprotkb:Macropain subunit C8(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C8(gene name synonym)|uniprotkb:HC8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_002779.1|refseq:NP_687033.1|ensembl:ENSG00000100567(gene)|ensembl:ENST00000216455(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0045202"(synapse)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR037555|mint:P25788|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|rcsb pdb:5DSV|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|rcsb pdb:7E55|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|rcsb pdb:5T0H|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-174084|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-174113|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|dip:DIP-29366N|uniprotkb:P25788(identity)|entrezgene/locuslink:5684(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:9Er/PY50/GVoCr5yAPXlkfxtP0k9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q9UK22 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-4287196|uniprotkb:B2R7K7|uniprotkb:Q5TGY0|uniprotkb:Q6FGJ7|uniprotkb:Q8TB29|uniprotkb:Q9UKC6|ensembl:ENSP00000346240 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fbx2_human(display_long)|uniprotkb:FBXO2(gene name)|psi-mi:FBXO2(display_short)|uniprotkb:FBX2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_036300.2|ensembl:ENSG00000116661(gene)|ensembl:ENST00000354287(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006508"(proteolysis)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0043197"(dendritic spine)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR007397(F-box associated region)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036047|interpro:IPR039752|mint:Q9UK22|reactome:R-HSA-8951664|reactome:R-HSA-983168|uniprotkb:Q9UK22(identity)|entrezgene/locuslink:26232(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:Ynr/gzgujCVKo9XgalXSfZdvm/Y9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q9Y2X7 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-466061|uniprotkb:Q86SS0|uniprotkb:Q9BRJ4|uniprotkb:B4DSV3|ensembl:ENSP00000225394|uniprotkb:B4DGU9 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:git1_human(display_long)|uniprotkb:GIT1(gene name)|psi-mi:GIT1(display_short)|uniprotkb:G protein-coupled receptor kinase-interactor 1(gene name synonym)|uniprotkb:GRK-interacting protein 1(gene name synonym)|uniprotkb:Cool-associated and tyrosine-phosphorylated protein 1(gene name synonym)|uniprotkb:p95-APP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_001078923.1|refseq:NP_054749.2|ensembl:ENSG00000108262(gene)|ensembl:ENST00000225394(transcript)|go:"GO:0001957"(intramembranous ossification)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007420"(brain development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0044305"(calyx of Held)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045820"(negative regulation of glycolytic process)|interpro:IPR013724("Spa2 homology (SHD) of GIT")|go:"GO:0046872"(metal ion binding)|interpro:IPR020683|go:"GO:0048013"(ephrin receptor signaling pathway)|interpro:IPR022018|interpro:IPR032352|interpro:IPR036770|interpro:IPR037278|go:"GO:0048666"(neuron development)|go:"GO:0061743"(motor learning)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0098794"(postsynapse)|go:"GO:0099171"(presynaptic modulation of chemical synaptic transmission)|go:"GO:0106015"(negative regulation of inflammatory response to wounding)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR038508|interpro:IPR001164(Arf GTPase activating protein)|mint:Q9Y2X7|interpro:IPR002110(Ankyrin)|reactome:R-HSA-3928664|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9619229|uniprotkb:Q9Y2X7(identity)|entrezgene/locuslink:28964(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:9POm+EVvD4/BQh6bApnpXCAZyZo9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q9Y3I1 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-1161222|uniprotkb:Q5TGC4|uniprotkb:Q96HM6|uniprotkb:Q9UF21|uniprotkb:Q9UKT2|uniprotkb:B4DNB3|ensembl:ENSP00000266087|uniprotkb:B4DWX5|uniprotkb:Q5TI86 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fbx7_human(display_long)|uniprotkb:FBXO7(gene name)|psi-mi:FBXO7(display_short)|uniprotkb:FBX7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_001028196.1|refseq:NP_036311.3|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045620"(negative regulation of lymphocyte differentiation)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0097409"(glial cytoplasmic inclusion)|go:"GO:0097414"(classical Lewy body)|go:"GO:0097462"(Lewy neurite)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1990037"(Lewy body core)|go:"GO:1990038"(Lewy body corona)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR021625|interpro:IPR029071|interpro:IPR036047|mint:Q9Y3I1|rcsb pdb:4L9C|rcsb pdb:4L9H|reactome:R-HSA-8951664|reactome:R-HSA-983168|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|ensembl:ENSG00000100225(gene)|ensembl:ENST00000266087(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|refseq:NP_001244919.1|dip:DIP-36125N|uniprotkb:Q9Y3I1(identity)|entrezgene/locuslink:25793(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:i2Mqtw28fJTLURYC+gwr6bcjBoY9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q96CD0 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-2321097|uniprotkb:Q9NUM0|ensembl:ENSP00000258200|ensembl:ENSP00000430490 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fbxl8_human(display_long)|uniprotkb:FBXL8(gene name)|psi-mi:FBXL8(display_short)|uniprotkb:FBL8(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 8(gene name synonym)|uniprotkb:F-box protein FBL8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_060848.2|ensembl:ENSG00000135722(gene)|ensembl:ENST00000258200(transcript)|ensembl:ENST00000519917(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR032675|interpro:IPR036047|interpro:IPR039592|reactome:R-HSA-8951664|reactome:R-HSA-983168|uniprotkb:Q96CD0(identity)|entrezgene/locuslink:55336(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:53H7VmqG5mI6/qwbUeAKkT55HsY9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q06587 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:O14818 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-603272|uniprotkb:Q9BR53|uniprotkb:Q9H4K5|uniprotkb:Q9UEU8|uniprotkb:B2R515|uniprotkb:Q5JXJ2|ensembl:ENSP00000359910 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:psa7_human(display_long)|uniprotkb:PSMA7(gene name)|psi-mi:PSMA7(display_short)|uniprotkb:Proteasome subunit RC6-1(gene name synonym)|uniprotkb:Proteasome subunit XAPC7(gene name synonym)|uniprotkb:HSPC(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_002783.1|dip:DIP-29363N|ensembl:ENSG00000101182(gene)|ensembl:ENST00000370873(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098794"(postsynapse)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035190|mint:O14818|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|uniprotkb:O14818(identity)|entrezgene/locuslink:5688(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:J1M+b+VK02BAn2OnZISjjlmO8dc9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q13309 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-456291|uniprotkb:Q8TDZ0|uniprotkb:Q8TDZ1|uniprotkb:Q9BV69|ensembl:ENSP00000274255|uniprotkb:A8K5E0|uniprotkb:B4DJT4 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:skp2_human(display_long)|uniprotkb:F-box protein Skp2(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p45(gene name synonym)|uniprotkb:p45skp2(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 1(gene name synonym)|uniprotkb:SKP2(gene name)|psi-mi:SKP2(display_short)|uniprotkb:FBXL1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) ensembl:ENSG00000145604(gene)|ensembl:ENST00000274255(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071460"(cellular response to cell-matrix adhesion)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|rcsb pdb:2ASS|rcsb pdb:2AST|interpro:IPR032675|rcsb pdb:7B5L|interpro:IPR036047|mint:Q13309|rcsb pdb:1FQV|rcsb pdb:7B5M|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|refseq:NP_005974.2|refseq:NP_116026.1|refseq:NP_001230049.1|dip:DIP-17011N|rcsb pdb:7B5R|reactome:R-HSA-174178|reactome:R-HSA-187577|reactome:R-HSA-5689880|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9687136|reactome:R-HSA-9708530|reactome:R-HSA-983168|uniprotkb:Q13309(identity)|entrezgene/locuslink:6502(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:VABxcX3qu0Yr6eRNYINqvAPhPMc9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q07065 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-702400|uniprotkb:Q504S5|uniprotkb:Q53ES6|ensembl:ENSP00000367265 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:ckap4_human(display_long)|uniprotkb:CKAP4(gene name)|psi-mi:CKAP4(display_short)|uniprotkb:63-kDa cytoskeleton-linking membrane protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_006816.2|ensembl:ENSG00000136026(gene)|ensembl:ENST00000378026(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042599"(lamellar body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028428|mint:Q07065|reactome:R-HSA-381426|reactome:R-HSA-5683826|reactome:R-HSA-6798695|reactome:R-HSA-8957275|reactome:R-HSA-9696264|reactome:R-HSA-9696270|uniprotkb:Q07065(identity)|entrezgene/locuslink:10970(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:Q1hrxqh5k4Myf7J0To8Ecm/xxs49606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q96EF6 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-2510157|ensembl:ENSP00000292852|ensembl:ENSP00000470361|ensembl:ENSP00000488997|ensembl:ENSP00000489327|uniprotkb:Q96LQ4 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fbx17_human(display_long)|uniprotkb:FBXO17(gene name)|psi-mi:FBXO17(display_short)|uniprotkb:FBG4(gene name synonym)|uniprotkb:FBX17(gene name synonym)|uniprotkb:FBX26(gene name synonym)|uniprotkb:FBXO26(gene name synonym)|uniprotkb:F-box only protein 26(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) ensembl:ENSG00000269190(gene)|ensembl:ENSG00000282954(gene)|ensembl:ENST00000634982(transcript)|ensembl:ENST00000635115(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR007397(F-box associated region)|interpro:IPR008979(Galactose-binding like)|ensembl:ENST00000292852(transcript)|ensembl:ENST00000595329(transcript)|interpro:IPR036047|interpro:IPR039752|mint:Q96EF6|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_079183.4|refseq:NP_680474.1|uniprotkb:Q96EF6(identity)|entrezgene/locuslink:115290(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:yc7kMZQhjtDMtTD97TFdPZnGPPk9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q14999 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-308606|uniprotkb:Q5T654|ensembl:ENSP00000265348|uniprotkb:B4DYZ0|uniprotkb:F5H0L1 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:cul7_human(display_long)|uniprotkb:CUL7(gene name)|psi-mi:CUL7(display_short)|uniprotkb:KIAA0076(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) ensembl:ENSG00000044090(gene)|ensembl:ENST00000265348(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001890"(placenta development)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:1990393"(3M complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR021097|interpro:IPR031223|interpro:IPR036317|interpro:IPR036388|mint:Q14999|rcsb pdb:2JNG|reactome:R-HSA-381038|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_001161842.1|refseq:NP_055595.2|dip:DIP-31618N|dip:DIP-60187N|uniprotkb:Q14999(identity)|entrezgene/locuslink:9820(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:8sODZSppCsuEgRmhSHp3UjwOf2M9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q6PJ61 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-2322982|ensembl:ENSP00000410007 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fbx46_human(display_long)|uniprotkb:FBXO46(gene name)|psi-mi:FBXO46(display_short)|uniprotkb:FBX46(gene name synonym)|uniprotkb:FBXO34L(gene name synonym)|uniprotkb:F-box only protein 34-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_001073938.1|refseq:NP_001316561.1|refseq:NP_001316562.1|refseq:NP_001316563.1|dip:DIP-52907N|ensembl:ENSG00000177051(gene)|ensembl:ENST00000317683(transcript)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR036047|interpro:IPR039594|uniprotkb:Q6PJ61(identity)|entrezgene/locuslink:23403(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:QCVnTEdLgDVr2bOTIYELyx2P86o9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:O14777 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N|uniprotkb:O14777(identity)|entrezgene/locuslink:10403(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q6PCT2 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-6664563|ensembl:ENSP00000455529|uniprotkb:A8MT10|uniprotkb:Q8N789|uniprotkb:Q9NT14 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fxl19_human(display_long)|uniprotkb:FBXL19(gene name)|psi-mi:FBXL19(display_short)|uniprotkb:FBL19(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 19(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) ensembl:ENSG00000099364(gene)|ensembl:ENST00000562319(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045322"(unmethylated CpG binding)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|mint:Q6PCT2|rcsb pdb:6ASB|reactome:R-HSA-8951664|reactome:R-HSA-983168|interpro:IPR019786|refseq:NP_001269280.1|refseq:NP_001093254.2|uniprotkb:Q6PCT2(identity)|entrezgene/locuslink:54620(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:wtar4oBKcxTqx7B6RWX9BQgriVY9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:P62877 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-398523|uniprotkb:Q8N6Z8|uniprotkb:Q9D1S2|uniprotkb:Q9WUK9|uniprotkb:Q9Y254|uniprotkb:B2RDY1|ensembl:ENSP00000216225 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:rbx1_human(display_long)|uniprotkb:RBX1(gene name)|psi-mi:RBX1(display_short)|uniprotkb:RNF75(gene name synonym)|uniprotkb:ROC1(gene name synonym)|uniprotkb:Regulator of cullins 1(gene name synonym)|uniprotkb:RING finger protein 75(gene name synonym)|uniprotkb:Protein ZYP(gene name synonym)|uniprotkb:RING-box protein 1(gene name synonym)|uniprotkb:E3 ubiquitin-protein transferase RBX1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_055063.1|dip:DIP-17014N|ensembl:ENSG00000100387(gene)|ensembl:ENST00000216225(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019788"(NEDD8 transferase activity)|go:"GO:0030891"(VCB complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045116"(protein neddylation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061663"(NEDD8 ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|mint:P62877|rcsb pdb:1LDJ|rcsb pdb:1LDK|rcsb pdb:1U6G|rcsb pdb:2HYE|rcsb pdb:2LGV|rcsb pdb:3DPL|rcsb pdb:3DQV|rcsb pdb:3RTR|rcsb pdb:4F52|rcsb pdb:4P5O|rcsb pdb:5N4W|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|rcsb pdb:6TTU|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7B5S|reactome:R-HSA-110314|reactome:R-HSA-1170546|reactome:R-HSA-1234176|reactome:R-HSA-180585|reactome:R-HSA-195253|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2894862|reactome:R-HSA-4641258|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-68949|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|uniprotkb:P62877(identity)|entrezgene/locuslink:9978(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:pSaSNRZo+QudTPXOLUlksOj3smM9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:P63167 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-349105|uniprotkb:Q15701|ensembl:ENSP00000242577|ensembl:ENSP00000376296|ensembl:ENSP00000376297|ensembl:ENSP00000446614|ensembl:ENSP00000447907 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:dyl1_human(display_long)|uniprotkb:DYNLL1(gene name)|psi-mi:DYNLL1(display_short)|uniprotkb:DLC1(gene name synonym)|uniprotkb:DNCLC1(gene name synonym)|uniprotkb:HDLC1(gene name synonym)|uniprotkb:Dynein light chain LC8-type 1(gene name synonym)|uniprotkb:8 kDa dynein light chain(gene name synonym)|uniprotkb:Protein inhibitor of neuronal nitric oxide synthase(gene name synonym)|uniprotkb:DNCL1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_001032583.1|refseq:NP_001032584.1|refseq:NP_003737.1|go:"GO:0072686"(mitotic spindle)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:P63167|rcsb pdb:1CMI|rcsb pdb:3ZKE|rcsb pdb:3ZKF|rcsb pdb:6GZJ|rcsb pdb:6GZL|rcsb pdb:6RLB|rcsb pdb:6SC2|rcsb pdb:7D35|reactome:R-HSA-111446|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|go:"GO:0000776"(kinetochore)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0005829"(cytosol)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007286"(spermatid development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030286"(dynein complex)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|ensembl:ENSG00000088986(gene)|ensembl:ENST00000242577(transcript)|ensembl:ENST00000392508(transcript)|ensembl:ENST00000392509(transcript)|ensembl:ENST00000548342(transcript)|ensembl:ENST00000549989(transcript)|dip:DIP-33150N|uniprotkb:P63167(identity)|entrezgene/locuslink:8655(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:Bra4LfaqYPMyo6xX9RD6G7Rdv809606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q15843 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-716247|uniprotkb:Q3SXN8|uniprotkb:Q6LES6|ensembl:ENSP00000250495|ensembl:ENSP00000496420 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:nedd8_human(display_long)|uniprotkb:Ubiquitin-like protein Nedd8(gene name synonym)|uniprotkb:Neddylin(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 8(gene name synonym)|uniprotkb:NEDD8(gene name)|psi-mi:NEDD8(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_006147.1|ensembl:ENSG00000129559(gene)|ensembl:ENSG00000285246(gene)|ensembl:ENST00000250495(transcript)|ensembl:ENST00000643069(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006508"(proteolysis)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008104"(protein localization)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045116"(protein neddylation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038738|mint:Q15843|rcsb pdb:1NDD|rcsb pdb:1R4M|rcsb pdb:1R4N|rcsb pdb:1XT9|rcsb pdb:2BKR|rcsb pdb:2KO3|rcsb pdb:2N7K|rcsb pdb:2NVU|rcsb pdb:3DBH|rcsb pdb:3DBL|rcsb pdb:3DBR|rcsb pdb:3DQV|rcsb pdb:3GZN|rcsb pdb:4F8C|rcsb pdb:4FBJ|rcsb pdb:4HCP|rcsb pdb:4P5O|rcsb pdb:6R7F|rcsb pdb:6R7I|rcsb pdb:6TTU|rcsb pdb:7B5L|rcsb pdb:7B5N|reactome:R-HSA-2173789|reactome:R-HSA-5689603|reactome:R-HSA-8856825|reactome:R-HSA-8951664|reactome:R-HSA-917937|dip:DIP-29266N|uniprotkb:Q15843(identity)|entrezgene/locuslink:4738(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:qB1KNoIOwa1ONfphWDWjJri9hwE9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q9H0W5 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-5236005|uniprotkb:Q8TB26|ensembl:ENSP00000303158 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:ccdc8_human(display_long)|uniprotkb:CCDC8(gene name)|psi-mi:CCDC8(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_114429.2|dip:DIP-60183N|ensembl:ENSG00000169515(gene)|ensembl:ENST00000307522(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:1990393"(3M complex)|interpro:IPR026523|mint:Q9H0W5|rcsb pdb:4LG6|reactome:R-HSA-8951664|uniprotkb:Q9H0W5(identity)|entrezgene/locuslink:83987(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:WZYxMX583xXAxpOLGC8gyR7+/fU9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q9UKB1 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-355189|uniprotkb:Q9P2S8|uniprotkb:Q9P2S9|uniprotkb:Q9Y4C6|uniprotkb:B2RC98|ensembl:ENSP00000265094 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fbw1b_human(display_long)|uniprotkb:KIAA0696(gene name synonym)|uniprotkb:FBXW11(gene name)|psi-mi:FBXW11(display_short)|uniprotkb:BTRCP2(gene name synonym)|uniprotkb:FBW1B(gene name synonym)|uniprotkb:FBXW1B(gene name synonym)|uniprotkb:F-box/WD repeat-containing protein 1B(gene name synonym)|uniprotkb:F-box and WD repeats protein beta-TrCP2(gene name synonym)|uniprotkb:Homologous to Slimb protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_036432.2|refseq:NP_387448.2|refseq:NP_387449.2|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007097"(nuclear migration)|go:"GO:0007281"(germ cell development)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031648"(protein destabilization)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0005635"(nuclear envelope)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0070840"(dynein complex binding)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021977|interpro:IPR036047|interpro:IPR036322|mint:Q9UKB1|rcsb pdb:6WNX|reactome:R-HSA-1169091|reactome:R-HSA-202424|reactome:R-HSA-2565942|reactome:R-HSA-2871837|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-8951664|reactome:R-HSA-983168|go:"GO:0048511"(rhythmic process)|ensembl:ENSG00000072803(gene)|ensembl:ENST00000265094(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000776"(kinetochore)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|dip:DIP-27593N|uniprotkb:Q9UKB1(identity)|entrezgene/locuslink:23291(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:8wLc2Pt+mLfRsNwXOnjho+1A0u09606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q8NEZ5 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-2510137|ensembl:ENSP00000307833|uniprotkb:Q9H824|uniprotkb:Q6PIL5|uniprotkb:Q9UKC0|uniprotkb:Q0D2P8|uniprotkb:Q8IXW3 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fbx22_human(display_long)|uniprotkb:FBXO22(gene name)|psi-mi:FBXO22(display_short)|uniprotkb:FBX22(gene name synonym)|uniprotkb:F-box protein FBX22p44(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) ensembl:ENSG00000167196(gene)|ensembl:ENST00000308275(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030018"(Z disc)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048742"(regulation of skeletal muscle fiber development)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR019494|interpro:IPR036047|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:XP_011519749.1|refseq:NP_036302.1|refseq:NP_671717.1|uniprotkb:Q8NEZ5(identity)|entrezgene/locuslink:26263(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:hOnBb3SK/OM+oGU8RdxmUb8MVDE9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q9UKT8 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-914727|uniprotkb:Q4VXH2|uniprotkb:Q7Z4V6|uniprotkb:Q8WV51|uniprotkb:Q9HA09|uniprotkb:Q9UKA3|uniprotkb:B3KRL8|ensembl:ENSP00000476369|ensembl:ENSP00000507010|ensembl:ENSP00000508157 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:fbxw2_human(display_long)|uniprotkb:FBXW2(gene name)|psi-mi:FBXW2(display_short)|uniprotkb:FBW2(gene name synonym)|uniprotkb:FWD2(gene name synonym)|uniprotkb:F-box and WD-40 domain-containing protein 2(gene name synonym)|uniprotkb:Protein MD6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_036296.2|refseq:XP_005251967.1|refseq:XP_016870104.1|dip:DIP-37972N|ensembl:ENSG00000119402(gene)|ensembl:ENST00000608872(transcript)|ensembl:ENST00000684001(transcript)|ensembl:ENST00000684047(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006508"(proteolysis)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036047|interpro:IPR036322|interpro:IPR042627|reactome:R-HSA-390471|reactome:R-HSA-8951664|reactome:R-HSA-983168|uniprotkb:Q9UKT8(identity)|entrezgene/locuslink:26190(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:SLs3xu8ssSvd7zsJ6gnpF/Is8ZE9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P63208 uniprotkb:Q92530 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 intact:EBI-945916|uniprotkb:A0AVQ9|uniprotkb:Q9H4I1|uniprotkb:D3DVW3|ensembl:ENSP00000327704|ensembl:ENSP00000338039 psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:psmf1_human(display_long)|uniprotkb:PSMF1(gene name)|psi-mi:PSMF1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835658|imex:IM-21659-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|ddbj/embl/genbank:BC025673(identity)|entrezgene/locuslink:6500(identity) refseq:NP_006805.2|refseq:NP_848693.2|refseq:NP_001310336.1|ensembl:ENSG00000125818(gene)|ensembl:ENST00000333082(transcript)|ensembl:ENST00000335877(transcript)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070628"(proteasome binding)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|interpro:IPR013886(PI31 proteasome regulator)|interpro:IPR021625|rcsb pdb:2VT8|rcsb pdb:4OUH|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|uniprotkb:Q92530(identity)|entrezgene/locuslink:9491(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2020/10/21 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rogid:QufCMzFs9wZBQO5l4iVOfn4dnvc9606 intact-crc:E3670763F0099D4D|rigid:9Tpr7NKSY8YAK7TIrh18ZL1Om9c false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UHJ3 uniprotkb:O60341 intact:EBI-747398|uniprotkb:Q96C73|uniprotkb:Q9Y4Q9|uniprotkb:Q402F7|ensembl:ENSP00000378235 intact:EBI-710124|uniprotkb:Q5TH94|uniprotkb:Q5TH95|uniprotkb:Q86VT7|uniprotkb:Q8IXK4|uniprotkb:Q8NDP6|uniprotkb:Q8TAZ3|uniprotkb:Q96AW4|ensembl:ENSP00000349049|uniprotkb:A8MWP9 psi-mi:smbt1_human(display_long)|uniprotkb:Renal ubiquitous protein 1(gene name synonym)|uniprotkb:SFMBT1(gene name)|psi-mi:SFMBT1(display_short)|uniprotkb:RU1(gene name synonym) psi-mi:kdm1a_human(display_long)|uniprotkb:Flavin-containing amine oxidase domain-containing protein 2(gene name synonym)|uniprotkb:BRAF35-HDAC complex protein BHC110(gene name synonym)|uniprotkb:KDM1A(gene name)|psi-mi:KDM1A(display_short)|uniprotkb:KIAA0601(gene name synonym)|uniprotkb:LSD1(gene name synonym)|uniprotkb:AOF2(gene name synonym)|uniprotkb:KDM1(gene name synonym)|uniprotkb:"[histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A"(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835984|imex:IM-21659-52 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006713266.1|refseq:XP_006713267.1|refseq:NP_057413.2|refseq:XP_011532126.1|refseq:XP_011532127.1|refseq:XP_005265278.1|ensembl:ENSG00000163935(gene)|ensembl:ENST00000394752(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048635"(negative regulation of muscle organ development)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR037604|interpro:IPR038348|mint:Q9UHJ3|uniprotkb:Q9UHJ3(identity)|ddbj/embl/genbank:BC014614(identity)|entrezgene/locuslink:51460(identity) go:"GO:0021987"(cerebral cortex development)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032451"(demethylase activity)|refseq:NP_001009999.1|refseq:NP_055828.2|ensembl:ENSG00000004487(gene)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|ensembl:ENST00000356634(transcript)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-34641N|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0033184"(positive regulation of histone ubiquitination)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042551"(neuron maturation)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043426"(MRF binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046098"(guanine metabolic process)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0060992"(response to fungicide)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061752"(telomeric repeat-containing RNA binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1903827"|go:"GO:1990391"(DNA repair complex)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000648"(positive regulation of stem cell proliferation)|interpro:IPR002937(Amine oxidase)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017366(Histone lysine-specific demethylase)|interpro:IPR036188|interpro:IPR036388|mint:O60341|rcsb pdb:2COM|rcsb pdb:2DW4|rcsb pdb:2EJR|rcsb pdb:2H94|rcsb pdb:2HKO|rcsb pdb:2IW5|rcsb pdb:2L3D|rcsb pdb:2UXN|rcsb pdb:2UXX|rcsb pdb:2V1D|rcsb pdb:2X0L|rcsb pdb:2XAF|rcsb pdb:2XAG|rcsb pdb:2XAH|rcsb pdb:2XAJ|rcsb pdb:2XAQ|rcsb pdb:2XAS|rcsb pdb:2Y48|rcsb pdb:2Z3Y|rcsb pdb:2Z5U|rcsb pdb:3ABT|rcsb pdb:3ABU|rcsb pdb:3ZMS|rcsb pdb:3ZMT|rcsb pdb:3ZMU|rcsb pdb:3ZMV|rcsb pdb:3ZMZ|rcsb pdb:3ZN0|rcsb pdb:3ZN1|rcsb pdb:4BAY|rcsb pdb:4CZZ|rcsb pdb:4KUM|rcsb pdb:4UV8|rcsb pdb:4UV9|rcsb pdb:4UVA|rcsb pdb:4UVB|rcsb pdb:4UVC|rcsb pdb:4UXN|rcsb pdb:4XBF|rcsb pdb:5AFW|rcsb pdb:5H6Q|rcsb pdb:5H6R|rcsb pdb:5IT3|rcsb pdb:5L3B|rcsb pdb:5L3C|rcsb pdb:5L3D|rcsb pdb:5L3E|rcsb pdb:5L3F|rcsb pdb:5L3G|rcsb pdb:5LBQ|rcsb pdb:5LGN|rcsb pdb:5LGT|rcsb pdb:5LGU|rcsb pdb:5LHG|rcsb pdb:5LHH|rcsb pdb:5LHI|rcsb pdb:5X60|rcsb pdb:5YJB|rcsb pdb:6E1F|rcsb pdb:6K3E|rcsb pdb:6KGK|rcsb pdb:6KGL|rcsb pdb:6KGM|rcsb pdb:6KGN|rcsb pdb:6KGO|rcsb pdb:6KGP|rcsb pdb:6KGQ|rcsb pdb:6KGR|rcsb pdb:6NQM|rcsb pdb:6NQU|rcsb pdb:6NR5|rcsb pdb:6S35|rcsb pdb:6TE1|rcsb pdb:6VYP|rcsb pdb:6W4K|rcsb pdb:6WC6|rcsb pdb:7CDC|rcsb pdb:7CDD|rcsb pdb:7CDE|rcsb pdb:7CDF|rcsb pdb:7CDG|rcsb pdb:7E0G|rcsb pdb:7JJL|rcsb pdb:7JJM|rcsb pdb:7JK7|reactome:R-HSA-3214815|reactome:R-HSA-3214842|reactome:R-HSA-5625886|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9679191|reactome:R-HSA-983231|uniprotkb:O60341(identity)|entrezgene/locuslink:23028(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:vh/dDMpcLQEo57Wcjnggufh6HRk9606 rogid:rS9F23Rg1Ha6XOQSisWQfhKVFfs9606 intact-crc:D29DD921D69F82D0|rigid:FMS4dvk4L3bMckdg/cAVeuHJJLE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UHJ3 uniprotkb:Q9P2K3 intact:EBI-747398|uniprotkb:Q96C73|uniprotkb:Q9Y4Q9|uniprotkb:Q402F7|ensembl:ENSP00000378235 intact:EBI-743428|uniprotkb:B3KYA2|uniprotkb:B4DYY7|uniprotkb:Q5VT47|uniprotkb:Q7L9I5|uniprotkb:Q8N5U3|uniprotkb:Q9NV83|ensembl:ENSP00000355972 psi-mi:smbt1_human(display_long)|uniprotkb:Renal ubiquitous protein 1(gene name synonym)|uniprotkb:SFMBT1(gene name)|psi-mi:SFMBT1(display_short)|uniprotkb:RU1(gene name synonym) psi-mi:rcor3_human(display_long)|uniprotkb:RCOR3(gene name)|psi-mi:RCOR3(display_short)|uniprotkb:KIAA1343(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835984|imex:IM-21659-52 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006713266.1|refseq:XP_006713267.1|refseq:NP_057413.2|refseq:XP_011532126.1|refseq:XP_011532127.1|refseq:XP_005265278.1|ensembl:ENSG00000163935(gene)|ensembl:ENST00000394752(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048635"(negative regulation of muscle organ development)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR037604|interpro:IPR038348|mint:Q9UHJ3|uniprotkb:Q9UHJ3(identity)|ddbj/embl/genbank:BC014614(identity)|entrezgene/locuslink:51460(identity) rcsb pdb:4CZZ|refseq:NP_001129695.1|refseq:NP_001129696.2|refseq:NP_001129697.1|refseq:NP_060724.1|ensembl:ENSG00000117625(gene)|ensembl:ENST00000367005(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016575"(histone deacetylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|mint:Q9P2K3|uniprotkb:Q9P2K3(identity)|entrezgene/locuslink:55758(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:vh/dDMpcLQEo57Wcjnggufh6HRk9606 rogid:hzuKCK7o/85XbN65z8Ua+XNaSJc9606 intact-crc:D29DD921D69F82D0|rigid:FMS4dvk4L3bMckdg/cAVeuHJJLE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UHJ3 uniprotkb:Q9UKL0 intact:EBI-747398|uniprotkb:Q96C73|uniprotkb:Q9Y4Q9|uniprotkb:Q402F7|ensembl:ENSP00000378235 intact:EBI-926563|uniprotkb:Q15044|uniprotkb:Q6P2I9|uniprotkb:Q86VG5|intact:EBI-11087913|uniprotkb:J3KN32|ensembl:ENSP00000262241 psi-mi:smbt1_human(display_long)|uniprotkb:Renal ubiquitous protein 1(gene name synonym)|uniprotkb:SFMBT1(gene name)|psi-mi:SFMBT1(display_short)|uniprotkb:RU1(gene name synonym) psi-mi:rcor1_human(display_long)|uniprotkb:RCOR1(gene name)|psi-mi:RCOR1(display_short)|uniprotkb:KIAA0071(gene name synonym)|uniprotkb:RCOR(gene name synonym)|uniprotkb:Protein CoREST(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835984|imex:IM-21659-52 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006713266.1|refseq:XP_006713267.1|refseq:NP_057413.2|refseq:XP_011532126.1|refseq:XP_011532127.1|refseq:XP_005265278.1|ensembl:ENSG00000163935(gene)|ensembl:ENST00000394752(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048635"(negative regulation of muscle organ development)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR037604|interpro:IPR038348|mint:Q9UHJ3|uniprotkb:Q9UHJ3(identity)|ddbj/embl/genbank:BC014614(identity)|entrezgene/locuslink:51460(identity) refseq:NP_055971.2|dip:DIP-35263N|ensembl:ENSG00000089902(gene)|ensembl:ENST00000262241(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0045654"(positive regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:1990391"(DNA repair complex)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|mint:Q9UKL0|rcsb pdb:2IW5|rcsb pdb:2UXN|rcsb pdb:2UXX|rcsb pdb:2V1D|rcsb pdb:2X0L|rcsb pdb:2XAF|rcsb pdb:2XAG|rcsb pdb:2XAH|rcsb pdb:2XAJ|rcsb pdb:2XAQ|rcsb pdb:2XAS|rcsb pdb:2Y48|rcsb pdb:3ZMS|rcsb pdb:3ZMT|rcsb pdb:3ZMU|rcsb pdb:3ZMV|rcsb pdb:3ZMZ|rcsb pdb:3ZN0|rcsb pdb:3ZN1|rcsb pdb:4BAY|rcsb pdb:4KUM|rcsb pdb:4UV8|rcsb pdb:4UV9|rcsb pdb:4UVA|rcsb pdb:4UVB|rcsb pdb:4UVC|rcsb pdb:4UXN|rcsb pdb:4XBF|rcsb pdb:5H6Q|rcsb pdb:5H6R|rcsb pdb:5L3B|rcsb pdb:5L3C|rcsb pdb:5L3D|rcsb pdb:5L3E|rcsb pdb:5L3F|rcsb pdb:5L3G|rcsb pdb:5LBQ|rcsb pdb:5LGN|rcsb pdb:5LGT|rcsb pdb:5LGU|rcsb pdb:5LHG|rcsb pdb:5LHH|rcsb pdb:5LHI|rcsb pdb:5X60|rcsb pdb:5YJB|rcsb pdb:6K3E|rcsb pdb:6KGK|rcsb pdb:6KGL|rcsb pdb:6KGM|rcsb pdb:6KGN|rcsb pdb:6S35|rcsb pdb:6TE1|rcsb pdb:6VYP|rcsb pdb:6W4K|rcsb pdb:6WC6|rcsb pdb:7CDC|rcsb pdb:7CDD|rcsb pdb:7CDE|rcsb pdb:7CDF|rcsb pdb:7CDG|reactome:R-HSA-3214815|reactome:R-HSA-8943724|reactome:R-HSA-9679191|reactome:R-HSA-983231|uniprotkb:Q9UKL0(identity)|entrezgene/locuslink:23186(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:vh/dDMpcLQEo57Wcjnggufh6HRk9606 rogid:B1KfnjicGzKdWGnGGrZwjgpMQ309606 intact-crc:D29DD921D69F82D0|rigid:FMS4dvk4L3bMckdg/cAVeuHJJLE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UHJ3 uniprotkb:O75362 intact:EBI-747398|uniprotkb:Q96C73|uniprotkb:Q9Y4Q9|uniprotkb:Q402F7|ensembl:ENSP00000378235 intact:EBI-6597704|ensembl:ENSP00000304308|ensembl:ENSP00000360526|uniprotkb:E1P5Y6|uniprotkb:Q14DB8 psi-mi:smbt1_human(display_long)|uniprotkb:Renal ubiquitous protein 1(gene name synonym)|uniprotkb:SFMBT1(gene name)|psi-mi:SFMBT1(display_short)|uniprotkb:RU1(gene name synonym) psi-mi:zn217_human(display_long)|uniprotkb:ZNF217(gene name)|psi-mi:ZNF217(display_short)|uniprotkb:ZABC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835984|imex:IM-21659-52 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006713266.1|refseq:XP_006713267.1|refseq:NP_057413.2|refseq:XP_011532126.1|refseq:XP_011532127.1|refseq:XP_005265278.1|ensembl:ENSG00000163935(gene)|ensembl:ENST00000394752(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048635"(negative regulation of muscle organ development)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR037604|interpro:IPR038348|mint:Q9UHJ3|uniprotkb:Q9UHJ3(identity)|ddbj/embl/genbank:BC014614(identity)|entrezgene/locuslink:51460(identity) ensembl:ENSG00000171940(gene)|ensembl:ENST00000302342(transcript)|ensembl:ENST00000371471(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016607"(nuclear speck)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:2HU2|rcsb pdb:3UK3|rcsb pdb:4F2J|rcsb pdb:4IS1|reactome:R-HSA-9018519|refseq:NP_006517.1|refseq:XP_016883548.1|uniprotkb:O75362(identity)|entrezgene/locuslink:7764(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:vh/dDMpcLQEo57Wcjnggufh6HRk9606 rogid:E65TwYRj7QeQtQbTWV8q91QlwQk9606 intact-crc:D29DD921D69F82D0|rigid:FMS4dvk4L3bMckdg/cAVeuHJJLE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UHJ3 uniprotkb:Q13547 intact:EBI-747398|uniprotkb:Q96C73|uniprotkb:Q9Y4Q9|uniprotkb:Q402F7|ensembl:ENSP00000378235 intact:EBI-301834|uniprotkb:Q92534|ensembl:ENSP00000362649 psi-mi:smbt1_human(display_long)|uniprotkb:Renal ubiquitous protein 1(gene name synonym)|uniprotkb:SFMBT1(gene name)|psi-mi:SFMBT1(display_short)|uniprotkb:RU1(gene name synonym) psi-mi:hdac1_human(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:RPD3L1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835984|imex:IM-21659-52 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006713266.1|refseq:XP_006713267.1|refseq:NP_057413.2|refseq:XP_011532126.1|refseq:XP_011532127.1|refseq:XP_005265278.1|ensembl:ENSG00000163935(gene)|ensembl:ENST00000394752(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048635"(negative regulation of muscle organ development)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR037604|interpro:IPR038348|mint:Q9UHJ3|uniprotkb:Q9UHJ3(identity)|ddbj/embl/genbank:BC014614(identity)|entrezgene/locuslink:51460(identity) ensembl:ENSG00000116478(gene)|ensembl:ENST00000373548(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007492"(endoderm development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031000"(response to caffeine)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043044"|go:"GO:0019213"(deacetylase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900221"(regulation of amyloid-beta clearance)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q13547|rcsb pdb:1TYI|rcsb pdb:4BKX|rcsb pdb:5ICN|rcsb pdb:6Z2J|rcsb pdb:6Z2K|rcsb pdb:7AO8|rcsb pdb:7AO9|rcsb pdb:7AOA|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-193670|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-3769402|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-4641265|reactome:R-HSA-6804758|reactome:R-HSA-69205|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9022538|reactome:R-HSA-9022692|go:"GO:0017053"(transcription repressor complex)|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9615017|reactome:R-HSA-9679191|reactome:R-HSA-983231|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:NP_004955.2|dip:DIP-24184N|uniprotkb:Q13547(identity)|entrezgene/locuslink:3065(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:vh/dDMpcLQEo57Wcjnggufh6HRk9606 rogid:RP+yIBWH55NgoPTY1nKXqeJL/xY9606 intact-crc:D29DD921D69F82D0|rigid:FMS4dvk4L3bMckdg/cAVeuHJJLE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UHJ3 uniprotkb:P63167 intact:EBI-747398|uniprotkb:Q96C73|uniprotkb:Q9Y4Q9|uniprotkb:Q402F7|ensembl:ENSP00000378235 intact:EBI-349105|uniprotkb:Q15701|ensembl:ENSP00000242577|ensembl:ENSP00000376296|ensembl:ENSP00000376297|ensembl:ENSP00000446614|ensembl:ENSP00000447907 psi-mi:smbt1_human(display_long)|uniprotkb:Renal ubiquitous protein 1(gene name synonym)|uniprotkb:SFMBT1(gene name)|psi-mi:SFMBT1(display_short)|uniprotkb:RU1(gene name synonym) psi-mi:dyl1_human(display_long)|uniprotkb:DYNLL1(gene name)|psi-mi:DYNLL1(display_short)|uniprotkb:DLC1(gene name synonym)|uniprotkb:DNCLC1(gene name synonym)|uniprotkb:HDLC1(gene name synonym)|uniprotkb:Dynein light chain LC8-type 1(gene name synonym)|uniprotkb:8 kDa dynein light chain(gene name synonym)|uniprotkb:Protein inhibitor of neuronal nitric oxide synthase(gene name synonym)|uniprotkb:DNCL1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835984|imex:IM-21659-52 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006713266.1|refseq:XP_006713267.1|refseq:NP_057413.2|refseq:XP_011532126.1|refseq:XP_011532127.1|refseq:XP_005265278.1|ensembl:ENSG00000163935(gene)|ensembl:ENST00000394752(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048635"(negative regulation of muscle organ development)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR037604|interpro:IPR038348|mint:Q9UHJ3|uniprotkb:Q9UHJ3(identity)|ddbj/embl/genbank:BC014614(identity)|entrezgene/locuslink:51460(identity) refseq:NP_001032583.1|refseq:NP_001032584.1|refseq:NP_003737.1|go:"GO:0072686"(mitotic spindle)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:P63167|rcsb pdb:1CMI|rcsb pdb:3ZKE|rcsb pdb:3ZKF|rcsb pdb:6GZJ|rcsb pdb:6GZL|rcsb pdb:6RLB|rcsb pdb:6SC2|rcsb pdb:7D35|reactome:R-HSA-111446|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|go:"GO:0000776"(kinetochore)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0005829"(cytosol)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007286"(spermatid development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030286"(dynein complex)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|ensembl:ENSG00000088986(gene)|ensembl:ENST00000242577(transcript)|ensembl:ENST00000392508(transcript)|ensembl:ENST00000392509(transcript)|ensembl:ENST00000548342(transcript)|ensembl:ENST00000549989(transcript)|dip:DIP-33150N|uniprotkb:P63167(identity)|entrezgene/locuslink:8655(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:vh/dDMpcLQEo57Wcjnggufh6HRk9606 rogid:Bra4LfaqYPMyo6xX9RD6G7Rdv809606 intact-crc:D29DD921D69F82D0|rigid:FMS4dvk4L3bMckdg/cAVeuHJJLE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UHJ3 uniprotkb:Q92769 intact:EBI-747398|uniprotkb:Q96C73|uniprotkb:Q9Y4Q9|uniprotkb:Q402F7|ensembl:ENSP00000378235 intact:EBI-301821|uniprotkb:Q5SRI8|uniprotkb:Q5SZ86|uniprotkb:Q8NEH4|uniprotkb:B4DL58|ensembl:ENSP00000430432|uniprotkb:E1P561|uniprotkb:B3KRS5 psi-mi:smbt1_human(display_long)|uniprotkb:Renal ubiquitous protein 1(gene name synonym)|uniprotkb:SFMBT1(gene name)|psi-mi:SFMBT1(display_short)|uniprotkb:RU1(gene name synonym) psi-mi:hdac2_human(display_long)|uniprotkb:HDAC2(gene name)|psi-mi:HDAC2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835984|imex:IM-21659-52 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006713266.1|refseq:XP_006713267.1|refseq:NP_057413.2|refseq:XP_011532126.1|refseq:XP_011532127.1|refseq:XP_005265278.1|ensembl:ENSG00000163935(gene)|ensembl:ENST00000394752(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048635"(negative regulation of muscle organ development)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR037604|interpro:IPR038348|mint:Q9UHJ3|uniprotkb:Q9UHJ3(identity)|ddbj/embl/genbank:BC014614(identity)|entrezgene/locuslink:51460(identity) go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035094"(response to nicotine)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042220"(response to cocaine)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q92769|rcsb pdb:3MAX|rcsb pdb:4LXZ|rcsb pdb:4LY1|rcsb pdb:5IWG|rcsb pdb:5IX0|rcsb pdb:6G3O|rcsb pdb:6WBW|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000196591(gene)|ensembl:ENST00000519065(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|rcsb pdb:6WHN|rcsb pdb:6WHO|rcsb pdb:6WHQ|rcsb pdb:6WHZ|rcsb pdb:6WI3|rcsb pdb:6XDM|rcsb pdb:6XEB|rcsb pdb:6XEC|rcsb pdb:7KBG|rcsb pdb:7KBH|rcsb pdb:7LTG|rcsb pdb:7LTK|rcsb pdb:7LTL|reactome:R-HSA-193670|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9615017|reactome:R-HSA-9619665|reactome:R-HSA-9679191|reactome:R-HSA-983231|rcsb pdb:6WBZ|refseq:NP_001518.3|dip:DIP-24220N|refseq:XP_011534090.1|refseq:XP_016866288.1|uniprotkb:Q92769(identity)|entrezgene/locuslink:3066(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:vh/dDMpcLQEo57Wcjnggufh6HRk9606 rogid:K4PpGz9E9/TrQZsgvrJuc+uYCn89606 intact-crc:D29DD921D69F82D0|rigid:FMS4dvk4L3bMckdg/cAVeuHJJLE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UHJ3 uniprotkb:Q14687 intact:EBI-747398|uniprotkb:Q96C73|uniprotkb:Q9Y4Q9|uniprotkb:Q402F7|ensembl:ENSP00000378235 intact:EBI-372619|uniprotkb:Q8IY61|uniprotkb:Q96GA4|uniprotkb:Q9BW09|uniprotkb:D3DUM4|ensembl:ENSP00000253458 psi-mi:smbt1_human(display_long)|uniprotkb:Renal ubiquitous protein 1(gene name synonym)|uniprotkb:SFMBT1(gene name)|psi-mi:SFMBT1(display_short)|uniprotkb:RU1(gene name synonym) psi-mi:gse1_human(display_long)|uniprotkb:GSE1(gene name)|psi-mi:GSE1(display_short)|uniprotkb:KIAA0182(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835984|imex:IM-21659-52 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006713266.1|refseq:XP_006713267.1|refseq:NP_057413.2|refseq:XP_011532126.1|refseq:XP_011532127.1|refseq:XP_005265278.1|ensembl:ENSG00000163935(gene)|ensembl:ENST00000394752(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048635"(negative regulation of muscle organ development)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR037604|interpro:IPR038348|mint:Q9UHJ3|uniprotkb:Q9UHJ3(identity)|ddbj/embl/genbank:BC014614(identity)|entrezgene/locuslink:51460(identity) refseq:NP_001127945.1|refseq:NP_055430.1|refseq:NP_001265113.1|ensembl:ENSG00000131149(gene)|ensembl:ENST00000253458(transcript)|interpro:IPR022207|interpro:IPR042337|uniprotkb:Q14687(identity)|entrezgene/locuslink:23199(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:vh/dDMpcLQEo57Wcjnggufh6HRk9606 rogid:demu8MwWIxvbEfrM+pBn3gDTUO09606 intact-crc:D29DD921D69F82D0|rigid:FMS4dvk4L3bMckdg/cAVeuHJJLE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UHJ3 uniprotkb:Q96FJ2 intact:EBI-747398|uniprotkb:Q96C73|uniprotkb:Q9Y4Q9|uniprotkb:Q402F7|ensembl:ENSP00000378235 intact:EBI-742371|uniprotkb:B2R5B4|ensembl:ENSP00000477310 psi-mi:smbt1_human(display_long)|uniprotkb:Renal ubiquitous protein 1(gene name synonym)|uniprotkb:SFMBT1(gene name)|psi-mi:SFMBT1(display_short)|uniprotkb:RU1(gene name synonym) psi-mi:dyl2_human(display_long)|uniprotkb:DYNLL2(gene name)|psi-mi:DYNLL2(display_short)|uniprotkb:Dynein light chain LC8-type 2(gene name synonym)|uniprotkb:DLC2(gene name synonym)|uniprotkb:8 kDa dynein light chain b(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835984|imex:IM-21659-52 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006713266.1|refseq:XP_006713267.1|refseq:NP_057413.2|refseq:XP_011532126.1|refseq:XP_011532127.1|refseq:XP_005265278.1|ensembl:ENSG00000163935(gene)|ensembl:ENST00000394752(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048635"(negative regulation of muscle organ development)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR037604|interpro:IPR038348|mint:Q9UHJ3|uniprotkb:Q9UHJ3(identity)|ddbj/embl/genbank:BC014614(identity)|entrezgene/locuslink:51460(identity) go:"GO:0005813"(centrosome)|refseq:NP_542408.1|ensembl:ENSG00000264364(gene)|ensembl:ENST00000579991(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007017"(microtubule-based process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030286"(dynein complex)|go:"GO:0031475"(myosin V complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:Q96FJ2|rcsb pdb:2XQQ|rcsb pdb:3P8M|rcsb pdb:4D07|reactome:R-HSA-139910|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|uniprotkb:Q96FJ2(identity)|entrezgene/locuslink:140735(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:vh/dDMpcLQEo57Wcjnggufh6HRk9606 rogid:4RFpJF40RBja5mOvt/aCv3miiDU9606 intact-crc:D29DD921D69F82D0|rigid:FMS4dvk4L3bMckdg/cAVeuHJJLE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UHJ3 uniprotkb:Q92766 intact:EBI-747398|uniprotkb:Q96C73|uniprotkb:Q9Y4Q9|uniprotkb:Q402F7|ensembl:ENSP00000378235 intact:EBI-1210379|uniprotkb:E2GM80|uniprotkb:E2GM81|uniprotkb:A2RRF5|uniprotkb:O75567|uniprotkb:O75568|uniprotkb:Q5VYB2|uniprotkb:Q6BEP5|uniprotkb:Q6BEP6|uniprotkb:Q6BEP8|uniprotkb:Q86SU2|uniprotkb:Q9Y474|ensembl:ENSP00000305560|ensembl:ENSP00000369265 psi-mi:smbt1_human(display_long)|uniprotkb:Renal ubiquitous protein 1(gene name synonym)|uniprotkb:SFMBT1(gene name)|psi-mi:SFMBT1(display_short)|uniprotkb:RU1(gene name synonym) psi-mi:rreb1_human(display_long)|uniprotkb:RREB1(gene name)|psi-mi:RREB1(display_short)|uniprotkb:FINB(gene name synonym)|uniprotkb:Raf-responsive zinc finger protein LZ321(gene name synonym)|uniprotkb:Zinc finger motif enhancer-binding protein 1(gene name synonym)|uniprotkb:Finger protein in nuclear bodies(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8835984|imex:IM-21659-52 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006713266.1|refseq:XP_006713267.1|refseq:NP_057413.2|refseq:XP_011532126.1|refseq:XP_011532127.1|refseq:XP_005265278.1|ensembl:ENSG00000163935(gene)|ensembl:ENST00000394752(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048635"(negative regulation of muscle organ development)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR037604|interpro:IPR038348|mint:Q9UHJ3|uniprotkb:Q9UHJ3(identity)|ddbj/embl/genbank:BC014614(identity)|entrezgene/locuslink:51460(identity) refseq:XP_011513097.1|refseq:NP_001003698.1|refseq:NP_001003699.1|refseq:NP_001003700.1|refseq:NP_001161816.1|refseq:XP_006715220.1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903691"(positive regulation of wound healing, spreading of epidermal cells)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|ensembl:ENSG00000124782(gene)|ensembl:ENST00000349384(transcript)|ensembl:ENST00000379933(transcript)|uniprotkb:Q92766(identity)|entrezgene/locuslink:6239(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:vh/dDMpcLQEo57Wcjnggufh6HRk9606 rogid:BKnzSXiZmB0IL9opvk8w6WiDMU49606 intact-crc:D29DD921D69F82D0|rigid:FMS4dvk4L3bMckdg/cAVeuHJJLE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43463 uniprotkb:P17987 intact:EBI-349968|uniprotkb:Q53G60|uniprotkb:Q6FHK6|ensembl:ENSP00000365877|uniprotkb:B2R6E8|uniprotkb:B4DST0 intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334 psi-mi:suv91_human(display_long)|uniprotkb:SUV39H1(gene name)|psi-mi:SUV39H1(display_short)|uniprotkb:SUV39H(gene name synonym)|uniprotkb:KMT1A(gene name synonym)|uniprotkb:Suppressor of variegation 3-9 homolog 1(gene name synonym)|uniprotkb:Position-effect variegation 3-9 homolog(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1A(gene name synonym) psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836034|imex:IM-21659-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003164.1|ensembl:ENSG00000101945(gene)|ensembl:ENST00000376687(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0006364"(rRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|mint:O43463|rcsb pdb:3MTS|reactome:R-HSA-3214841|reactome:R-HSA-427359|refseq:NP_001269095.1|dip:DIP-32589N|uniprotkb:O43463(identity)|ddbj/embl/genbank:BC006238(identity)|entrezgene/locuslink:6839(identity) refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N|uniprotkb:P17987(identity)|entrezgene/locuslink:6950(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:dbenLwo5hxhGzFD4sLNOVUveElM9606 rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606 intact-crc:F0D7D04762BA8A51|rigid:bzqWEWr733jTpkIkZIuKhRq2GUw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43463 uniprotkb:Q99832 intact:EBI-349968|uniprotkb:Q53G60|uniprotkb:Q6FHK6|ensembl:ENSP00000365877|uniprotkb:B2R6E8|uniprotkb:B4DST0 intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091 psi-mi:suv91_human(display_long)|uniprotkb:SUV39H1(gene name)|psi-mi:SUV39H1(display_short)|uniprotkb:SUV39H(gene name synonym)|uniprotkb:KMT1A(gene name synonym)|uniprotkb:Suppressor of variegation 3-9 homolog 1(gene name synonym)|uniprotkb:Position-effect variegation 3-9 homolog(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1A(gene name synonym) psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836034|imex:IM-21659-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003164.1|ensembl:ENSG00000101945(gene)|ensembl:ENST00000376687(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0006364"(rRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|mint:O43463|rcsb pdb:3MTS|reactome:R-HSA-3214841|reactome:R-HSA-427359|refseq:NP_001269095.1|dip:DIP-32589N|uniprotkb:O43463(identity)|ddbj/embl/genbank:BC006238(identity)|entrezgene/locuslink:6839(identity) dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|uniprotkb:Q99832(identity)|entrezgene/locuslink:10574(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:dbenLwo5hxhGzFD4sLNOVUveElM9606 rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606 intact-crc:F0D7D04762BA8A51|rigid:bzqWEWr733jTpkIkZIuKhRq2GUw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43463 uniprotkb:P48643 intact:EBI-349968|uniprotkb:Q53G60|uniprotkb:Q6FHK6|ensembl:ENSP00000365877|uniprotkb:B2R6E8|uniprotkb:B4DST0 intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8 psi-mi:suv91_human(display_long)|uniprotkb:SUV39H1(gene name)|psi-mi:SUV39H1(display_short)|uniprotkb:SUV39H(gene name synonym)|uniprotkb:KMT1A(gene name synonym)|uniprotkb:Suppressor of variegation 3-9 homolog 1(gene name synonym)|uniprotkb:Position-effect variegation 3-9 homolog(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1A(gene name synonym) psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836034|imex:IM-21659-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003164.1|ensembl:ENSG00000101945(gene)|ensembl:ENST00000376687(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0006364"(rRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|mint:O43463|rcsb pdb:3MTS|reactome:R-HSA-3214841|reactome:R-HSA-427359|refseq:NP_001269095.1|dip:DIP-32589N|uniprotkb:O43463(identity)|ddbj/embl/genbank:BC006238(identity)|entrezgene/locuslink:6839(identity) refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N|uniprotkb:P48643(identity)|entrezgene/locuslink:22948(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:dbenLwo5hxhGzFD4sLNOVUveElM9606 rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606 intact-crc:F0D7D04762BA8A51|rigid:bzqWEWr733jTpkIkZIuKhRq2GUw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43463 uniprotkb:P45973 intact:EBI-349968|uniprotkb:Q53G60|uniprotkb:Q6FHK6|ensembl:ENSP00000365877|uniprotkb:B2R6E8|uniprotkb:B4DST0 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 psi-mi:suv91_human(display_long)|uniprotkb:SUV39H1(gene name)|psi-mi:SUV39H1(display_short)|uniprotkb:SUV39H(gene name synonym)|uniprotkb:KMT1A(gene name synonym)|uniprotkb:Suppressor of variegation 3-9 homolog 1(gene name synonym)|uniprotkb:Position-effect variegation 3-9 homolog(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1A(gene name synonym) psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836034|imex:IM-21659-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003164.1|ensembl:ENSG00000101945(gene)|ensembl:ENST00000376687(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0006364"(rRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|mint:O43463|rcsb pdb:3MTS|reactome:R-HSA-3214841|reactome:R-HSA-427359|refseq:NP_001269095.1|dip:DIP-32589N|uniprotkb:O43463(identity)|ddbj/embl/genbank:BC006238(identity)|entrezgene/locuslink:6839(identity) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|entrezgene/locuslink:23468(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:dbenLwo5hxhGzFD4sLNOVUveElM9606 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 intact-crc:F0D7D04762BA8A51|rigid:bzqWEWr733jTpkIkZIuKhRq2GUw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43463 uniprotkb:P78371 intact:EBI-349968|uniprotkb:Q53G60|uniprotkb:Q6FHK6|ensembl:ENSP00000365877|uniprotkb:B2R6E8|uniprotkb:B4DST0 intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300 psi-mi:suv91_human(display_long)|uniprotkb:SUV39H1(gene name)|psi-mi:SUV39H1(display_short)|uniprotkb:SUV39H(gene name synonym)|uniprotkb:KMT1A(gene name synonym)|uniprotkb:Suppressor of variegation 3-9 homolog 1(gene name synonym)|uniprotkb:Position-effect variegation 3-9 homolog(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1A(gene name synonym) psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836034|imex:IM-21659-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003164.1|ensembl:ENSG00000101945(gene)|ensembl:ENST00000376687(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0006364"(rRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|mint:O43463|rcsb pdb:3MTS|reactome:R-HSA-3214841|reactome:R-HSA-427359|refseq:NP_001269095.1|dip:DIP-32589N|uniprotkb:O43463(identity)|ddbj/embl/genbank:BC006238(identity)|entrezgene/locuslink:6839(identity) refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695|uniprotkb:P78371(identity)|entrezgene/locuslink:10576(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:dbenLwo5hxhGzFD4sLNOVUveElM9606 rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606 intact-crc:F0D7D04762BA8A51|rigid:bzqWEWr733jTpkIkZIuKhRq2GUw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43463 uniprotkb:P50991 intact:EBI-349968|uniprotkb:Q53G60|uniprotkb:Q6FHK6|ensembl:ENSP00000365877|uniprotkb:B2R6E8|uniprotkb:B4DST0 intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958 psi-mi:suv91_human(display_long)|uniprotkb:SUV39H1(gene name)|psi-mi:SUV39H1(display_short)|uniprotkb:SUV39H(gene name synonym)|uniprotkb:KMT1A(gene name synonym)|uniprotkb:Suppressor of variegation 3-9 homolog 1(gene name synonym)|uniprotkb:Position-effect variegation 3-9 homolog(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1A(gene name synonym) psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836034|imex:IM-21659-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003164.1|ensembl:ENSG00000101945(gene)|ensembl:ENST00000376687(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0006364"(rRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|mint:O43463|rcsb pdb:3MTS|reactome:R-HSA-3214841|reactome:R-HSA-427359|refseq:NP_001269095.1|dip:DIP-32589N|uniprotkb:O43463(identity)|ddbj/embl/genbank:BC006238(identity)|entrezgene/locuslink:6839(identity) refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998|uniprotkb:P50991(identity)|entrezgene/locuslink:10575(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:dbenLwo5hxhGzFD4sLNOVUveElM9606 rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606 intact-crc:F0D7D04762BA8A51|rigid:bzqWEWr733jTpkIkZIuKhRq2GUw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43463 uniprotkb:P40227 intact:EBI-349968|uniprotkb:Q53G60|uniprotkb:Q6FHK6|ensembl:ENSP00000365877|uniprotkb:B2R6E8|uniprotkb:B4DST0 intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2 psi-mi:suv91_human(display_long)|uniprotkb:SUV39H1(gene name)|psi-mi:SUV39H1(display_short)|uniprotkb:SUV39H(gene name synonym)|uniprotkb:KMT1A(gene name synonym)|uniprotkb:Suppressor of variegation 3-9 homolog 1(gene name synonym)|uniprotkb:Position-effect variegation 3-9 homolog(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1A(gene name synonym) psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836034|imex:IM-21659-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003164.1|ensembl:ENSG00000101945(gene)|ensembl:ENST00000376687(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0006364"(rRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|mint:O43463|rcsb pdb:3MTS|reactome:R-HSA-3214841|reactome:R-HSA-427359|refseq:NP_001269095.1|dip:DIP-32589N|uniprotkb:O43463(identity)|ddbj/embl/genbank:BC006238(identity)|entrezgene/locuslink:6839(identity) refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N|uniprotkb:P40227(identity)|entrezgene/locuslink:908(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:dbenLwo5hxhGzFD4sLNOVUveElM9606 rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606 intact-crc:F0D7D04762BA8A51|rigid:bzqWEWr733jTpkIkZIuKhRq2GUw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43463 uniprotkb:P83916 intact:EBI-349968|uniprotkb:Q53G60|uniprotkb:Q6FHK6|ensembl:ENSP00000365877|uniprotkb:B2R6E8|uniprotkb:B4DST0 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 psi-mi:suv91_human(display_long)|uniprotkb:SUV39H1(gene name)|psi-mi:SUV39H1(display_short)|uniprotkb:SUV39H(gene name synonym)|uniprotkb:KMT1A(gene name synonym)|uniprotkb:Suppressor of variegation 3-9 homolog 1(gene name synonym)|uniprotkb:Position-effect variegation 3-9 homolog(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1A(gene name synonym) psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836034|imex:IM-21659-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003164.1|ensembl:ENSG00000101945(gene)|ensembl:ENST00000376687(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0006364"(rRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|mint:O43463|rcsb pdb:3MTS|reactome:R-HSA-3214841|reactome:R-HSA-427359|refseq:NP_001269095.1|dip:DIP-32589N|uniprotkb:O43463(identity)|ddbj/embl/genbank:BC006238(identity)|entrezgene/locuslink:6839(identity) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|entrezgene/locuslink:10951(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:dbenLwo5hxhGzFD4sLNOVUveElM9606 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 intact-crc:F0D7D04762BA8A51|rigid:bzqWEWr733jTpkIkZIuKhRq2GUw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43463 uniprotkb:P01106 intact:EBI-349968|uniprotkb:Q53G60|uniprotkb:Q6FHK6|ensembl:ENSP00000365877|uniprotkb:B2R6E8|uniprotkb:B4DST0 intact:EBI-447544|intact:EBI-1058440|uniprotkb:P01107|uniprotkb:Q14026|uniprotkb:A8WFE7|ensembl:ENSP00000367207|ensembl:ENSP00000499105 psi-mi:suv91_human(display_long)|uniprotkb:SUV39H1(gene name)|psi-mi:SUV39H1(display_short)|uniprotkb:SUV39H(gene name synonym)|uniprotkb:KMT1A(gene name synonym)|uniprotkb:Suppressor of variegation 3-9 homolog 1(gene name synonym)|uniprotkb:Position-effect variegation 3-9 homolog(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1A(gene name synonym) psi-mi:myc_human(display_long)|uniprotkb:BHLHE39(gene name synonym)|uniprotkb:Transcription factor p64(gene name synonym)|uniprotkb:MYC(gene name)|psi-mi:MYC(display_short)|uniprotkb:Proto-oncogene c-Myc(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 39(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836034|imex:IM-21659-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003164.1|ensembl:ENSG00000101945(gene)|ensembl:ENST00000376687(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0006364"(rRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|mint:O43463|rcsb pdb:3MTS|reactome:R-HSA-3214841|reactome:R-HSA-427359|refseq:NP_001269095.1|dip:DIP-32589N|uniprotkb:O43463(identity)|ddbj/embl/genbank:BC006238(identity)|entrezgene/locuslink:6839(identity) refseq:NP_002458.2|dip:DIP-28143N|ensembl:ENSG00000136997(gene)|ensembl:ENST00000377970(transcript)|ensembl:ENST00000652288(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035690"|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044346"(fibroblast apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045656"(negative regulation of monocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051276"(chromosome organization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070848"(response to growth factor)|go:"GO:0070888"(E-box binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090096"(positive regulation of metanephric cap mesenchymal cell proliferation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1904672"(regulation of somatic stem cell population maintenance)|go:"GO:1905643"(positive regulation of DNA methylation)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR002418(Transcription regulator Myc)|interpro:IPR003327(Leucine zipper, Myc)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR012682(Transcription regulator Myc, N-terminal)|interpro:IPR036638|mint:P01106|rcsb pdb:1A93|rcsb pdb:1EE4|rcsb pdb:1MV0|rcsb pdb:1NKP|rcsb pdb:2A93|rcsb pdb:2OR9|rcsb pdb:4Y7R|rcsb pdb:5I4Z|rcsb pdb:5I50|rcsb pdb:6C4U|rcsb pdb:6E16|rcsb pdb:6E24|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015671"(oxygen transport)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0032986"(protein-DNA complex disassembly)|go:"GO:0032991"(protein-containing complex)|reactome:R-HSA-2122947|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-4411364|reactome:R-HSA-5687128|reactome:R-HSA-5689880|reactome:R-HSA-6785807|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8866911|reactome:R-HSA-8951430|reactome:R-HSA-9018519|reactome:R-HSA-9616222|uniprotkb:P01106(identity)|entrezgene/locuslink:4609(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:dbenLwo5hxhGzFD4sLNOVUveElM9606 rogid:CCk+p9FN7JV6cTmJDlin2hRp1tg9606 intact-crc:F0D7D04762BA8A51|rigid:bzqWEWr733jTpkIkZIuKhRq2GUw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43463 uniprotkb:P49368 intact:EBI-349968|uniprotkb:Q53G60|uniprotkb:Q6FHK6|ensembl:ENSP00000365877|uniprotkb:B2R6E8|uniprotkb:B4DST0 intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688 psi-mi:suv91_human(display_long)|uniprotkb:SUV39H1(gene name)|psi-mi:SUV39H1(display_short)|uniprotkb:SUV39H(gene name synonym)|uniprotkb:KMT1A(gene name synonym)|uniprotkb:Suppressor of variegation 3-9 homolog 1(gene name synonym)|uniprotkb:Position-effect variegation 3-9 homolog(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1A(gene name synonym) psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836034|imex:IM-21659-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003164.1|ensembl:ENSG00000101945(gene)|ensembl:ENST00000376687(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0006364"(rRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|mint:O43463|rcsb pdb:3MTS|reactome:R-HSA-3214841|reactome:R-HSA-427359|refseq:NP_001269095.1|dip:DIP-32589N|uniprotkb:O43463(identity)|ddbj/embl/genbank:BC006238(identity)|entrezgene/locuslink:6839(identity) refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N|uniprotkb:P49368(identity)|entrezgene/locuslink:7203(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:dbenLwo5hxhGzFD4sLNOVUveElM9606 rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606 intact-crc:F0D7D04762BA8A51|rigid:bzqWEWr733jTpkIkZIuKhRq2GUw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43463 uniprotkb:O75556 intact:EBI-349968|uniprotkb:Q53G60|uniprotkb:Q6FHK6|ensembl:ENSP00000365877|uniprotkb:B2R6E8|uniprotkb:B4DST0 intact:EBI-8830751|ensembl:ENSP00000244930 psi-mi:suv91_human(display_long)|uniprotkb:SUV39H1(gene name)|psi-mi:SUV39H1(display_short)|uniprotkb:SUV39H(gene name synonym)|uniprotkb:KMT1A(gene name synonym)|uniprotkb:Suppressor of variegation 3-9 homolog 1(gene name synonym)|uniprotkb:Position-effect variegation 3-9 homolog(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1A(gene name synonym) psi-mi:sg2a1_human(display_long)|uniprotkb:LIPHC(gene name synonym)|uniprotkb:Lacryglobin(gene name synonym)|uniprotkb:Lipophilin-C(gene name synonym)|uniprotkb:MGB2(gene name synonym)|uniprotkb:Mammaglobin-2(gene name synonym)|uniprotkb:Secretoglobin family 2A member 1(gene name synonym)|uniprotkb:UGB3(gene name synonym)|uniprotkb:SCGB2A1(gene name)|psi-mi:SCGB2A1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836034|imex:IM-21659-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003164.1|ensembl:ENSG00000101945(gene)|ensembl:ENST00000376687(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0006364"(rRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|mint:O43463|rcsb pdb:3MTS|reactome:R-HSA-3214841|reactome:R-HSA-427359|refseq:NP_001269095.1|dip:DIP-32589N|uniprotkb:O43463(identity)|ddbj/embl/genbank:BC006238(identity)|entrezgene/locuslink:6839(identity) refseq:NP_002398.1|ensembl:ENSG00000124939(gene)|ensembl:ENST00000244930(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0030521"(androgen receptor signaling pathway)|interpro:IPR016126(Secretoglobin)|interpro:IPR035960|uniprotkb:O75556(identity)|entrezgene/locuslink:4246(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:dbenLwo5hxhGzFD4sLNOVUveElM9606 rogid:w+3NKAb7Len68q3aS4Re1qKbOac9606 intact-crc:F0D7D04762BA8A51|rigid:bzqWEWr733jTpkIkZIuKhRq2GUw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43463 uniprotkb:Q8IWI9 intact:EBI-349968|uniprotkb:Q53G60|uniprotkb:Q6FHK6|ensembl:ENSP00000365877|uniprotkb:B2R6E8|uniprotkb:B4DST0 intact:EBI-2815196|uniprotkb:E7ENI0|uniprotkb:F5H7K2|uniprotkb:Q9H9N7|uniprotkb:Q9H8R3|uniprotkb:Q9Y4E9|uniprotkb:Q9UG69|intact:EBI-11143500|intact:EBI-10969960|ensembl:ENSP00000219905|uniprotkb:B9EGR5 psi-mi:suv91_human(display_long)|uniprotkb:SUV39H1(gene name)|psi-mi:SUV39H1(display_short)|uniprotkb:SUV39H(gene name synonym)|uniprotkb:KMT1A(gene name synonym)|uniprotkb:Suppressor of variegation 3-9 homolog 1(gene name synonym)|uniprotkb:Position-effect variegation 3-9 homolog(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1A(gene name synonym) psi-mi:mgap_human(display_long)|uniprotkb:MGA(gene name)|psi-mi:MGA(display_short)|uniprotkb:KIAA0518(gene name synonym)|uniprotkb:MAD5(gene name synonym)|uniprotkb:MAX dimerization protein 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836034|imex:IM-21659-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003164.1|ensembl:ENSG00000101945(gene)|ensembl:ENST00000376687(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0006364"(rRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|mint:O43463|rcsb pdb:3MTS|reactome:R-HSA-3214841|reactome:R-HSA-427359|refseq:NP_001269095.1|dip:DIP-32589N|uniprotkb:O43463(identity)|ddbj/embl/genbank:BC006238(identity)|entrezgene/locuslink:6839(identity) refseq:NP_001074010.2|ensembl:ENSP00000219905|ensembl:ENST00000566586|ensembl:ENSP00000456141|ensembl:ENSG00000174197(gene)|ensembl:ENST00000219905(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR018186|interpro:IPR032060|interpro:IPR036638|interpro:IPR036960|interpro:IPR037935|mint:Q8IWI9|reactome:R-HSA-8953750|refseq:NP_001157745.1|dip:DIP-57615N|uniprotkb:Q8IWI9(identity)|entrezgene/locuslink:23269(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:dbenLwo5hxhGzFD4sLNOVUveElM9606 rogid:P4lo9EteCvikQQk5kyVkcobitLU9606 intact-crc:F0D7D04762BA8A51|rigid:bzqWEWr733jTpkIkZIuKhRq2GUw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43463 uniprotkb:Q14839 intact:EBI-349968|uniprotkb:Q53G60|uniprotkb:Q6FHK6|ensembl:ENSP00000365877|uniprotkb:B2R6E8|uniprotkb:B4DST0 intact:EBI-372916|uniprotkb:Q8IXZ5|intact:EBI-28978241|ensembl:ENSP00000440542 psi-mi:suv91_human(display_long)|uniprotkb:SUV39H1(gene name)|psi-mi:SUV39H1(display_short)|uniprotkb:SUV39H(gene name synonym)|uniprotkb:KMT1A(gene name synonym)|uniprotkb:Suppressor of variegation 3-9 homolog 1(gene name synonym)|uniprotkb:Position-effect variegation 3-9 homolog(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1A(gene name synonym) psi-mi:chd4_human(display_long)|uniprotkb:CHD4(gene name)|psi-mi:CHD4(display_short)|uniprotkb:ATP-dependent helicase CHD4(gene name synonym)|uniprotkb:Mi-2 autoantigen 218 kDa protein(gene name synonym)|uniprotkb:Mi2-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836034|imex:IM-21659-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003164.1|ensembl:ENSG00000101945(gene)|ensembl:ENST00000376687(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0006364"(rRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|mint:O43463|rcsb pdb:3MTS|reactome:R-HSA-3214841|reactome:R-HSA-427359|refseq:NP_001269095.1|dip:DIP-32589N|uniprotkb:O43463(identity)|ddbj/embl/genbank:BC006238(identity)|entrezgene/locuslink:6839(identity) ensembl:ENSP00000440542|ensembl:ENST00000645095|ensembl:ENSP00000496634|refseq:NP_001264.2|refseq:XP_006719021.1|refseq:NP_001284482.1|ensembl:ENSG00000111642(gene)|ensembl:ENST00000544040(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070615"|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q14839|rcsb pdb:1MM2|rcsb pdb:1MM3|rcsb pdb:2EE1|rcsb pdb:2L5U|rcsb pdb:2L75|rcsb pdb:2N5N|rcsb pdb:4O9I|rcsb pdb:6BGG|rcsb pdb:6Q3M|rcsb pdb:6RYR|rcsb pdb:6RYU|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9031628|reactome:R-HSA-9679191|dip:DIP-31183N|uniprotkb:Q14839(identity)|entrezgene/locuslink:1108(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:dbenLwo5hxhGzFD4sLNOVUveElM9606 rogid:E9eHT/41SIFRiz54J81hvPQeHIE9606 intact-crc:F0D7D04762BA8A51|rigid:bzqWEWr733jTpkIkZIuKhRq2GUw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43463 uniprotkb:P50990 intact:EBI-349968|uniprotkb:Q53G60|uniprotkb:Q6FHK6|ensembl:ENSP00000365877|uniprotkb:B2R6E8|uniprotkb:B4DST0 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:suv91_human(display_long)|uniprotkb:SUV39H1(gene name)|psi-mi:SUV39H1(display_short)|uniprotkb:SUV39H(gene name synonym)|uniprotkb:KMT1A(gene name synonym)|uniprotkb:Suppressor of variegation 3-9 homolog 1(gene name synonym)|uniprotkb:Position-effect variegation 3-9 homolog(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1A(gene name synonym) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836034|imex:IM-21659-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003164.1|ensembl:ENSG00000101945(gene)|ensembl:ENST00000376687(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0006364"(rRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|mint:O43463|rcsb pdb:3MTS|reactome:R-HSA-3214841|reactome:R-HSA-427359|refseq:NP_001269095.1|dip:DIP-32589N|uniprotkb:O43463(identity)|ddbj/embl/genbank:BC006238(identity)|entrezgene/locuslink:6839(identity) refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N|uniprotkb:P50990(identity)|entrezgene/locuslink:10694(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:dbenLwo5hxhGzFD4sLNOVUveElM9606 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 intact-crc:F0D7D04762BA8A51|rigid:bzqWEWr733jTpkIkZIuKhRq2GUw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43463 uniprotkb:O60281 intact:EBI-349968|uniprotkb:Q53G60|uniprotkb:Q6FHK6|ensembl:ENSP00000365877|uniprotkb:B2R6E8|uniprotkb:B4DST0 intact:EBI-1224010|uniprotkb:Q9H8G3|uniprotkb:Q9H8J4|uniprotkb:Q5W0B2|uniprotkb:Q7Z3L7|intact:EBI-28971048|ensembl:ENSP00000358590 psi-mi:suv91_human(display_long)|uniprotkb:SUV39H1(gene name)|psi-mi:SUV39H1(display_short)|uniprotkb:SUV39H(gene name synonym)|uniprotkb:KMT1A(gene name synonym)|uniprotkb:Suppressor of variegation 3-9 homolog 1(gene name synonym)|uniprotkb:Position-effect variegation 3-9 homolog(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1A(gene name synonym) psi-mi:zn292_human(display_long)|uniprotkb:ZNF292(gene name)|psi-mi:ZNF292(display_short)|uniprotkb:KIAA0530(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836034|imex:IM-21659-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003164.1|ensembl:ENSG00000101945(gene)|ensembl:ENST00000376687(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0006364"(rRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|mint:O43463|rcsb pdb:3MTS|reactome:R-HSA-3214841|reactome:R-HSA-427359|refseq:NP_001269095.1|dip:DIP-32589N|uniprotkb:O43463(identity)|ddbj/embl/genbank:BC006238(identity)|entrezgene/locuslink:6839(identity) ensembl:ENSP00000358590|refseq:NP_055836.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|ensembl:ENSG00000188994(gene)|interpro:IPR036236|mint:O60281|rcsb pdb:1X3C|ensembl:ENST00000369577(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|uniprotkb:O60281(identity)|entrezgene/locuslink:23036(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:dbenLwo5hxhGzFD4sLNOVUveElM9606 rogid:4Ss6SyxGv1bSjSBhSjquUKutB349606 intact-crc:F0D7D04762BA8A51|rigid:bzqWEWr733jTpkIkZIuKhRq2GUw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43463 uniprotkb:Q13185 intact:EBI-349968|uniprotkb:Q53G60|uniprotkb:Q6FHK6|ensembl:ENSP00000365877|uniprotkb:B2R6E8|uniprotkb:B4DST0 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:suv91_human(display_long)|uniprotkb:SUV39H1(gene name)|psi-mi:SUV39H1(display_short)|uniprotkb:SUV39H(gene name synonym)|uniprotkb:KMT1A(gene name synonym)|uniprotkb:Suppressor of variegation 3-9 homolog 1(gene name synonym)|uniprotkb:Position-effect variegation 3-9 homolog(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1A(gene name synonym) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836034|imex:IM-21659-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003164.1|ensembl:ENSG00000101945(gene)|ensembl:ENST00000376687(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0006364"(rRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|mint:O43463|rcsb pdb:3MTS|reactome:R-HSA-3214841|reactome:R-HSA-427359|refseq:NP_001269095.1|dip:DIP-32589N|uniprotkb:O43463(identity)|ddbj/embl/genbank:BC006238(identity)|entrezgene/locuslink:6839(identity) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:dbenLwo5hxhGzFD4sLNOVUveElM9606 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 intact-crc:F0D7D04762BA8A51|rigid:bzqWEWr733jTpkIkZIuKhRq2GUw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H5I1 uniprotkb:P22531 intact:EBI-723127|ensembl:ENSP00000346997|uniprotkb:Q5JSS5|uniprotkb:Q6I9Y3|uniprotkb:Q8ND06|uniprotkb:Q5JSS4|uniprotkb:D3DRT4 intact:EBI-2556846|uniprotkb:Q5T9T4|uniprotkb:Q96RM2|ensembl:ENSP00000357739|ensembl:ENSP00000357740 psi-mi:suv92_human(display_long)|uniprotkb:KMT1B(gene name synonym)|uniprotkb:Suppressor of variegation 3-9 homolog 2(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 2(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1B(gene name synonym)|uniprotkb:SUV39H2(gene name)|psi-mi:SUV39H2(display_short) psi-mi:spr2e_human(display_long)|uniprotkb:Small proline-rich protein II(gene name synonym)|uniprotkb:SPRR2E(gene name)|psi-mi:SPRR2E(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836108|imex:IM-21659-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001180354.1|refseq:NP_001180355.1|refseq:NP_001180356.1|refseq:NP_078946.1|refseq:NP_001180353.1|ensembl:ENSG00000152455(gene)|ensembl:ENST00000354919(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048511"(rhythmic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|mint:Q9H5I1|rcsb pdb:2R3A|rcsb pdb:6P0R|reactome:R-HSA-3214841|refseq:XP_011517964.1|refseq:XP_006717566.1|refseq:XP_016872126.1|uniprotkb:Q9H5I1(identity)|ddbj/embl/genbank:BC007754(identity)|entrezgene/locuslink:79723(identity) refseq:NP_001019380.2|ensembl:ENSG00000203785(gene)|ensembl:ENST00000368750(transcript)|ensembl:ENST00000368751(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0031424"(keratinization)|interpro:IPR029142|mint:P22531|reactome:R-HSA-6809371|uniprotkb:P22531(identity)|entrezgene/locuslink:6704(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:hMEEzQCuAMnrbHg3HkLOfp8UH7k9606 rogid:Pwemojva9RHkLb7mVmctpxenpf49606 intact-crc:915228EA26E3D4F7|rigid:Nk7zk8WNk6AmVPjiRTbHhMwbPAs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H5I1 uniprotkb:P62891 intact:EBI-723127|ensembl:ENSP00000346997|uniprotkb:Q5JSS5|uniprotkb:Q6I9Y3|uniprotkb:Q8ND06|uniprotkb:Q5JSS4|uniprotkb:D3DRT4 intact:EBI-8830744|uniprotkb:P02404|uniprotkb:Q9BYF2|uniprotkb:P39025|ensembl:ENSP00000355315 psi-mi:suv92_human(display_long)|uniprotkb:KMT1B(gene name synonym)|uniprotkb:Suppressor of variegation 3-9 homolog 2(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 2(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1B(gene name synonym)|uniprotkb:SUV39H2(gene name)|psi-mi:SUV39H2(display_short) psi-mi:rl39_human(display_long)|uniprotkb:RPL39(gene name)|psi-mi:RPL39(display_short)|uniprotkb:Large ribosomal subunit protein eL39(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836108|imex:IM-21659-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001180354.1|refseq:NP_001180355.1|refseq:NP_001180356.1|refseq:NP_078946.1|refseq:NP_001180353.1|ensembl:ENSG00000152455(gene)|ensembl:ENST00000354919(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048511"(rhythmic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|mint:Q9H5I1|rcsb pdb:2R3A|rcsb pdb:6P0R|reactome:R-HSA-3214841|refseq:XP_011517964.1|refseq:XP_006717566.1|refseq:XP_016872126.1|uniprotkb:Q9H5I1(identity)|ddbj/embl/genbank:BC007754(identity)|entrezgene/locuslink:79723(identity) refseq:NP_000991.1|rcsb pdb:4V6X|ensembl:ENSG00000198918(gene)|ensembl:ENST00000361575(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000077(Ribosomal protein L39e)|interpro:IPR020083|interpro:IPR023626|rcsb pdb:4UG0|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|uniprotkb:P62891(identity)|entrezgene/locuslink:6170(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:hMEEzQCuAMnrbHg3HkLOfp8UH7k9606 rogid:AZus2dxwJsTxAOwnJ93E2yhasbo9606 intact-crc:915228EA26E3D4F7|rigid:Nk7zk8WNk6AmVPjiRTbHhMwbPAs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H5I1 uniprotkb:P50991 intact:EBI-723127|ensembl:ENSP00000346997|uniprotkb:Q5JSS5|uniprotkb:Q6I9Y3|uniprotkb:Q8ND06|uniprotkb:Q5JSS4|uniprotkb:D3DRT4 intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958 psi-mi:suv92_human(display_long)|uniprotkb:KMT1B(gene name synonym)|uniprotkb:Suppressor of variegation 3-9 homolog 2(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 2(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1B(gene name synonym)|uniprotkb:SUV39H2(gene name)|psi-mi:SUV39H2(display_short) psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836108|imex:IM-21659-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001180354.1|refseq:NP_001180355.1|refseq:NP_001180356.1|refseq:NP_078946.1|refseq:NP_001180353.1|ensembl:ENSG00000152455(gene)|ensembl:ENST00000354919(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048511"(rhythmic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|mint:Q9H5I1|rcsb pdb:2R3A|rcsb pdb:6P0R|reactome:R-HSA-3214841|refseq:XP_011517964.1|refseq:XP_006717566.1|refseq:XP_016872126.1|uniprotkb:Q9H5I1(identity)|ddbj/embl/genbank:BC007754(identity)|entrezgene/locuslink:79723(identity) refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998|uniprotkb:P50991(identity)|entrezgene/locuslink:10575(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:hMEEzQCuAMnrbHg3HkLOfp8UH7k9606 rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606 intact-crc:915228EA26E3D4F7|rigid:Nk7zk8WNk6AmVPjiRTbHhMwbPAs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H5I1 uniprotkb:P40227 intact:EBI-723127|ensembl:ENSP00000346997|uniprotkb:Q5JSS5|uniprotkb:Q6I9Y3|uniprotkb:Q8ND06|uniprotkb:Q5JSS4|uniprotkb:D3DRT4 intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2 psi-mi:suv92_human(display_long)|uniprotkb:KMT1B(gene name synonym)|uniprotkb:Suppressor of variegation 3-9 homolog 2(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 2(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1B(gene name synonym)|uniprotkb:SUV39H2(gene name)|psi-mi:SUV39H2(display_short) psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836108|imex:IM-21659-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001180354.1|refseq:NP_001180355.1|refseq:NP_001180356.1|refseq:NP_078946.1|refseq:NP_001180353.1|ensembl:ENSG00000152455(gene)|ensembl:ENST00000354919(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048511"(rhythmic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|mint:Q9H5I1|rcsb pdb:2R3A|rcsb pdb:6P0R|reactome:R-HSA-3214841|refseq:XP_011517964.1|refseq:XP_006717566.1|refseq:XP_016872126.1|uniprotkb:Q9H5I1(identity)|ddbj/embl/genbank:BC007754(identity)|entrezgene/locuslink:79723(identity) refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N|uniprotkb:P40227(identity)|entrezgene/locuslink:908(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:hMEEzQCuAMnrbHg3HkLOfp8UH7k9606 rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606 intact-crc:915228EA26E3D4F7|rigid:Nk7zk8WNk6AmVPjiRTbHhMwbPAs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H5I1 uniprotkb:P49368 intact:EBI-723127|ensembl:ENSP00000346997|uniprotkb:Q5JSS5|uniprotkb:Q6I9Y3|uniprotkb:Q8ND06|uniprotkb:Q5JSS4|uniprotkb:D3DRT4 intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688 psi-mi:suv92_human(display_long)|uniprotkb:KMT1B(gene name synonym)|uniprotkb:Suppressor of variegation 3-9 homolog 2(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 2(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1B(gene name synonym)|uniprotkb:SUV39H2(gene name)|psi-mi:SUV39H2(display_short) psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836108|imex:IM-21659-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001180354.1|refseq:NP_001180355.1|refseq:NP_001180356.1|refseq:NP_078946.1|refseq:NP_001180353.1|ensembl:ENSG00000152455(gene)|ensembl:ENST00000354919(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048511"(rhythmic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|mint:Q9H5I1|rcsb pdb:2R3A|rcsb pdb:6P0R|reactome:R-HSA-3214841|refseq:XP_011517964.1|refseq:XP_006717566.1|refseq:XP_016872126.1|uniprotkb:Q9H5I1(identity)|ddbj/embl/genbank:BC007754(identity)|entrezgene/locuslink:79723(identity) refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N|uniprotkb:P49368(identity)|entrezgene/locuslink:7203(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:hMEEzQCuAMnrbHg3HkLOfp8UH7k9606 rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606 intact-crc:915228EA26E3D4F7|rigid:Nk7zk8WNk6AmVPjiRTbHhMwbPAs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H5I1 uniprotkb:P50990 intact:EBI-723127|ensembl:ENSP00000346997|uniprotkb:Q5JSS5|uniprotkb:Q6I9Y3|uniprotkb:Q8ND06|uniprotkb:Q5JSS4|uniprotkb:D3DRT4 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:suv92_human(display_long)|uniprotkb:KMT1B(gene name synonym)|uniprotkb:Suppressor of variegation 3-9 homolog 2(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 2(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1B(gene name synonym)|uniprotkb:SUV39H2(gene name)|psi-mi:SUV39H2(display_short) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836108|imex:IM-21659-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001180354.1|refseq:NP_001180355.1|refseq:NP_001180356.1|refseq:NP_078946.1|refseq:NP_001180353.1|ensembl:ENSG00000152455(gene)|ensembl:ENST00000354919(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048511"(rhythmic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|mint:Q9H5I1|rcsb pdb:2R3A|rcsb pdb:6P0R|reactome:R-HSA-3214841|refseq:XP_011517964.1|refseq:XP_006717566.1|refseq:XP_016872126.1|uniprotkb:Q9H5I1(identity)|ddbj/embl/genbank:BC007754(identity)|entrezgene/locuslink:79723(identity) refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N|uniprotkb:P50990(identity)|entrezgene/locuslink:10694(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:hMEEzQCuAMnrbHg3HkLOfp8UH7k9606 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 intact-crc:915228EA26E3D4F7|rigid:Nk7zk8WNk6AmVPjiRTbHhMwbPAs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H5I1 uniprotkb:Q99832 intact:EBI-723127|ensembl:ENSP00000346997|uniprotkb:Q5JSS5|uniprotkb:Q6I9Y3|uniprotkb:Q8ND06|uniprotkb:Q5JSS4|uniprotkb:D3DRT4 intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091 psi-mi:suv92_human(display_long)|uniprotkb:KMT1B(gene name synonym)|uniprotkb:Suppressor of variegation 3-9 homolog 2(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 2(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1B(gene name synonym)|uniprotkb:SUV39H2(gene name)|psi-mi:SUV39H2(display_short) psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836108|imex:IM-21659-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001180354.1|refseq:NP_001180355.1|refseq:NP_001180356.1|refseq:NP_078946.1|refseq:NP_001180353.1|ensembl:ENSG00000152455(gene)|ensembl:ENST00000354919(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048511"(rhythmic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|mint:Q9H5I1|rcsb pdb:2R3A|rcsb pdb:6P0R|reactome:R-HSA-3214841|refseq:XP_011517964.1|refseq:XP_006717566.1|refseq:XP_016872126.1|uniprotkb:Q9H5I1(identity)|ddbj/embl/genbank:BC007754(identity)|entrezgene/locuslink:79723(identity) dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|uniprotkb:Q99832(identity)|entrezgene/locuslink:10574(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:hMEEzQCuAMnrbHg3HkLOfp8UH7k9606 rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606 intact-crc:915228EA26E3D4F7|rigid:Nk7zk8WNk6AmVPjiRTbHhMwbPAs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H5I1 uniprotkb:P05089 intact:EBI-723127|ensembl:ENSP00000346997|uniprotkb:Q5JSS5|uniprotkb:Q6I9Y3|uniprotkb:Q8ND06|uniprotkb:Q5JSS4|uniprotkb:D3DRT4 intact:EBI-2513844|uniprotkb:Q5JWT6|uniprotkb:Q5JWT5|uniprotkb:Q9BS50|uniprotkb:Q8TE72|uniprotkb:A6NEA0|ensembl:ENSP00000357066 psi-mi:suv92_human(display_long)|uniprotkb:KMT1B(gene name synonym)|uniprotkb:Suppressor of variegation 3-9 homolog 2(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 2(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1B(gene name synonym)|uniprotkb:SUV39H2(gene name)|psi-mi:SUV39H2(display_short) psi-mi:argi1_human(display_long)|uniprotkb:ARG1(gene name)|psi-mi:ARG1(display_short)|uniprotkb:Type I arginase(gene name synonym)|uniprotkb:Liver-type arginase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836108|imex:IM-21659-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001180354.1|refseq:NP_001180355.1|refseq:NP_001180356.1|refseq:NP_078946.1|refseq:NP_001180353.1|ensembl:ENSG00000152455(gene)|ensembl:ENST00000354919(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048511"(rhythmic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|mint:Q9H5I1|rcsb pdb:2R3A|rcsb pdb:6P0R|reactome:R-HSA-3214841|refseq:XP_011517964.1|refseq:XP_006717566.1|refseq:XP_016872126.1|uniprotkb:Q9H5I1(identity)|ddbj/embl/genbank:BC007754(identity)|entrezgene/locuslink:79723(identity) refseq:NP_000036.2|refseq:NP_001231367.1|ensembl:ENSG00000118520(gene)|ensembl:ENST00000368087(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0001889"(liver development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004053"(arginase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006527"(arginine catabolic process)|go:"GO:0007568"(aging)|go:"GO:0009635"(response to herbicide)|go:"GO:0010042"(response to manganese ion)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010963"|go:"GO:0014075"(response to amine)|go:"GO:0019547"(arginine catabolic process to ornithine)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030324"(lung development)|go:"GO:0032964"(collagen biosynthetic process)|go:"GO:0033189"(response to vitamin A)|go:"GO:0033197"(response to vitamin E)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043200"(response to amino acid)|go:"GO:0045087"(innate immune response)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048678"(response to axon injury)|go:"GO:0051597"(response to methylmercury)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070965"(positive regulation of neutrophil mediated killing of fungus)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071377"(cellular response to glucagon stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:2000552"(negative regulation of T-helper 2 cell cytokine production)|interpro:IPR006035(Ureohydrolase)|interpro:IPR014033(Arginase, subgroup)|go:"GO:0060056"(mammary gland involution)|interpro:IPR020855|interpro:IPR023696|mint:P05089|rcsb pdb:1WVA|rcsb pdb:1WVB|rcsb pdb:2AEB|rcsb pdb:2PHA|rcsb pdb:2PHO|rcsb pdb:2PLL|rcsb pdb:2ZAV|rcsb pdb:3DJ8|rcsb pdb:3E6K|rcsb pdb:3E6V|rcsb pdb:3F80|rcsb pdb:3GMZ|rcsb pdb:3GN0|rcsb pdb:3KV2|rcsb pdb:3LP4|rcsb pdb:3LP7|rcsb pdb:3MFV|rcsb pdb:3MFW|rcsb pdb:3MJL|rcsb pdb:3SJT|rcsb pdb:3SKK|rcsb pdb:3TF3|rcsb pdb:3TH7|rcsb pdb:3THE|rcsb pdb:3THH|rcsb pdb:3THJ|rcsb pdb:4FCI|rcsb pdb:4FCK|rcsb pdb:4GSM|rcsb pdb:4GSV|rcsb pdb:4GSZ|rcsb pdb:4GWC|rcsb pdb:4GWD|rcsb pdb:4HWW|rcsb pdb:4HXQ|rcsb pdb:4IE1|rcsb pdb:6Q92|rcsb pdb:6Q9P|rcsb pdb:6QAF|rcsb pdb:6V7C|rcsb pdb:6V7D|rcsb pdb:6V7E|rcsb pdb:6V7F|reactome:R-HSA-6798695|reactome:R-HSA-70635|uniprotkb:P05089(identity)|entrezgene/locuslink:383(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:hMEEzQCuAMnrbHg3HkLOfp8UH7k9606 rogid:b8HHscDekWZdN1S4OxFTA6rjvn89606 intact-crc:915228EA26E3D4F7|rigid:Nk7zk8WNk6AmVPjiRTbHhMwbPAs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H5I1 uniprotkb:Q9BQE3 intact:EBI-723127|ensembl:ENSP00000346997|uniprotkb:Q5JSS5|uniprotkb:Q6I9Y3|uniprotkb:Q8ND06|uniprotkb:Q5JSS4|uniprotkb:D3DRT4 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:suv92_human(display_long)|uniprotkb:KMT1B(gene name synonym)|uniprotkb:Suppressor of variegation 3-9 homolog 2(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 2(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1B(gene name synonym)|uniprotkb:SUV39H2(gene name)|psi-mi:SUV39H2(display_short) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836108|imex:IM-21659-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001180354.1|refseq:NP_001180355.1|refseq:NP_001180356.1|refseq:NP_078946.1|refseq:NP_001180353.1|ensembl:ENSG00000152455(gene)|ensembl:ENST00000354919(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048511"(rhythmic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|mint:Q9H5I1|rcsb pdb:2R3A|rcsb pdb:6P0R|reactome:R-HSA-3214841|refseq:XP_011517964.1|refseq:XP_006717566.1|refseq:XP_016872126.1|uniprotkb:Q9H5I1(identity)|ddbj/embl/genbank:BC007754(identity)|entrezgene/locuslink:79723(identity) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1|uniprotkb:Q9BQE3(identity)|entrezgene/locuslink:84790(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:hMEEzQCuAMnrbHg3HkLOfp8UH7k9606 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:915228EA26E3D4F7|rigid:Nk7zk8WNk6AmVPjiRTbHhMwbPAs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H5I1 uniprotkb:P48643 intact:EBI-723127|ensembl:ENSP00000346997|uniprotkb:Q5JSS5|uniprotkb:Q6I9Y3|uniprotkb:Q8ND06|uniprotkb:Q5JSS4|uniprotkb:D3DRT4 intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8 psi-mi:suv92_human(display_long)|uniprotkb:KMT1B(gene name synonym)|uniprotkb:Suppressor of variegation 3-9 homolog 2(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 2(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1B(gene name synonym)|uniprotkb:SUV39H2(gene name)|psi-mi:SUV39H2(display_short) psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836108|imex:IM-21659-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001180354.1|refseq:NP_001180355.1|refseq:NP_001180356.1|refseq:NP_078946.1|refseq:NP_001180353.1|ensembl:ENSG00000152455(gene)|ensembl:ENST00000354919(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048511"(rhythmic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|mint:Q9H5I1|rcsb pdb:2R3A|rcsb pdb:6P0R|reactome:R-HSA-3214841|refseq:XP_011517964.1|refseq:XP_006717566.1|refseq:XP_016872126.1|uniprotkb:Q9H5I1(identity)|ddbj/embl/genbank:BC007754(identity)|entrezgene/locuslink:79723(identity) refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N|uniprotkb:P48643(identity)|entrezgene/locuslink:22948(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:hMEEzQCuAMnrbHg3HkLOfp8UH7k9606 rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606 intact-crc:915228EA26E3D4F7|rigid:Nk7zk8WNk6AmVPjiRTbHhMwbPAs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H5I1 uniprotkb:P17987 intact:EBI-723127|ensembl:ENSP00000346997|uniprotkb:Q5JSS5|uniprotkb:Q6I9Y3|uniprotkb:Q8ND06|uniprotkb:Q5JSS4|uniprotkb:D3DRT4 intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334 psi-mi:suv92_human(display_long)|uniprotkb:KMT1B(gene name synonym)|uniprotkb:Suppressor of variegation 3-9 homolog 2(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 2(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1B(gene name synonym)|uniprotkb:SUV39H2(gene name)|psi-mi:SUV39H2(display_short) psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836108|imex:IM-21659-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001180354.1|refseq:NP_001180355.1|refseq:NP_001180356.1|refseq:NP_078946.1|refseq:NP_001180353.1|ensembl:ENSG00000152455(gene)|ensembl:ENST00000354919(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048511"(rhythmic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|mint:Q9H5I1|rcsb pdb:2R3A|rcsb pdb:6P0R|reactome:R-HSA-3214841|refseq:XP_011517964.1|refseq:XP_006717566.1|refseq:XP_016872126.1|uniprotkb:Q9H5I1(identity)|ddbj/embl/genbank:BC007754(identity)|entrezgene/locuslink:79723(identity) refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N|uniprotkb:P17987(identity)|entrezgene/locuslink:6950(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:hMEEzQCuAMnrbHg3HkLOfp8UH7k9606 rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606 intact-crc:915228EA26E3D4F7|rigid:Nk7zk8WNk6AmVPjiRTbHhMwbPAs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15022 uniprotkb:Q16576 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836162|imex:IM-21659-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:Q15022(identity)|entrezgene/locuslink:23512(identity) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N|uniprotkb:Q16576(identity)|entrezgene/locuslink:5931(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 intact-crc:6BD01B3974721D6A|rigid:Qxs+dn+UPmun8pYcqT2ZdMAvuQ8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15022 uniprotkb:Q96JN0 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 intact:EBI-746045|uniprotkb:Q9H945|uniprotkb:Q9Y457|ensembl:ENSP00000348298|ensembl:ENSP00000360138|ensembl:ENSP00000360144|ensembl:ENSP00000501560|ensembl:ENSP00000501639|ensembl:ENSP00000502633|intact:EBI-8833163|uniprotkb:D3DR47|uniprotkb:Q5VW16|uniprotkb:Q7Z723|uniprotkb:Q86T32|uniprotkb:Q86T33|uniprotkb:Q8N3L6|uniprotkb:Q8N655 psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:lcor_human(display_long)|uniprotkb:LCOR(gene name)|psi-mi:LCOR(display_short)|uniprotkb:C10orf12(gene name synonym)|uniprotkb:KIAA1795(gene name synonym)|uniprotkb:MLR2(gene name synonym)|uniprotkb:Mblk1-related protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836162|imex:IM-21659-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:Q15022(identity)|entrezgene/locuslink:23512(identity) ensembl:ENSG00000196233(gene)|ensembl:ENST00000356016(transcript)|ensembl:ENST00000371097(transcript)|ensembl:ENST00000371103(transcript)|ensembl:ENST00000675471(transcript)|ensembl:ENST00000675537(transcript)|ensembl:ENST00000675971(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|mint:Q96JN0|rcsb pdb:2COB|refseq:NP_001164236.1|refseq:NP_001164237.1|refseq:NP_115816.2|refseq:XP_016872275.1|refseq:XP_016872276.1|refseq:XP_016872277.1|refseq:NP_001333445.1|uniprotkb:Q8N655(identity)|entrezgene/locuslink:26148(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 rogid:cOnk6EDDff86yaG1uG+dxEQ1Z689606 intact-crc:6BD01B3974721D6A|rigid:Qxs+dn+UPmun8pYcqT2ZdMAvuQ8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15022 uniprotkb:Q6ZN18 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 intact:EBI-743256|ensembl:ENSP00000381840|uniprotkb:Q59FS5|uniprotkb:Q6ZN62|uniprotkb:Q96BG3 psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:aebp2_human(display_long)|uniprotkb:Adipocyte enhancer-binding protein 2(gene name synonym)|uniprotkb:AEBP2(gene name)|psi-mi:AEBP2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836162|imex:IM-21659-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:Q15022(identity)|entrezgene/locuslink:23512(identity) ensembl:ENSG00000139154(gene)|interpro:IPR036236|ensembl:ENST00000398864(transcript)|go:"GO:0000785"(chromatin)|mint:Q6ZN18|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001107648.1|refseq:NP_694939.2|rcsb pdb:5WAI|rcsb pdb:5Y0U|rcsb pdb:5Y1U|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|reactome:R-HSA-3214841|refseq:NP_001253972.1|dip:DIP-58581N|uniprotkb:Q6ZN18(identity)|entrezgene/locuslink:121536(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 rogid:mOY+NOTaqJlXjW8v6D3YPnfnfBU9606 intact-crc:6BD01B3974721D6A|rigid:Qxs+dn+UPmun8pYcqT2ZdMAvuQ8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15022 uniprotkb:Q09028 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836162|imex:IM-21659-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:Q15022(identity)|entrezgene/locuslink:23512(identity) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N|uniprotkb:Q09028(identity)|entrezgene/locuslink:5928(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 intact-crc:6BD01B3974721D6A|rigid:Qxs+dn+UPmun8pYcqT2ZdMAvuQ8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15022 uniprotkb:Q9Y483 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 intact:EBI-725816|uniprotkb:A6NGQ9|uniprotkb:Q9UES9|uniprotkb:Q9UP40|uniprotkb:A8K2Q3|uniprotkb:B1AKT5|intact:EBI-11028207|uniprotkb:Q96G26|uniprotkb:B1AKT6|ensembl:ENSP00000359321 psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:mtf2_human(display_long)|uniprotkb:PCL2(gene name synonym)|uniprotkb:Metal-response element DNA-binding protein M96(gene name synonym)|uniprotkb:Metal regulatory transcription factor 2(gene name synonym)|uniprotkb:Polycomb-like protein 2(gene name synonym)|uniprotkb:MTF2(gene name)|psi-mi:MTF2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836162|imex:IM-21659-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:Q15022(identity)|entrezgene/locuslink:23512(identity) refseq:NP_001157863.1|refseq:NP_001157865.1|refseq:NP_031384.1|refseq:XP_011539318.1|refseq:XP_016856165.1|ensembl:ENSG00000143033(gene)|ensembl:ENST00000370298(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042015|mint:Q9Y483|rcsb pdb:5XFR|reactome:R-HSA-212300|interpro:IPR042014|refseq:NP_001157864.1|uniprotkb:Q9Y483(identity)|entrezgene/locuslink:22823(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 rogid:Im8E6U/OPb8AEir43AUUDlU6F2o9606 intact-crc:6BD01B3974721D6A|rigid:Qxs+dn+UPmun8pYcqT2ZdMAvuQ8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15022 uniprotkb:A6NHQ4 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 intact:EBI-8831125|ensembl:ENSP00000483859|ensembl:ENSP00000484710 psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:epop_human(display_long)|uniprotkb:EPOP(gene name)|psi-mi:EPOP(display_short)|uniprotkb:C17orf96(gene name synonym)|uniprotkb:PRR28(gene name synonym)|uniprotkb:Proline-rich protein 28(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836162|imex:IM-21659-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:Q15022(identity)|entrezgene/locuslink:23512(identity) refseq:NP_001124149.1|ensembl:ENSG00000273604(gene)|ensembl:ENST00000613024(transcript)|ensembl:ENST00000621654(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005694"(chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0070449"(elongin complex)|interpro:IPR027971|mint:A6NHQ4|ensembl:ENSG00000277303(gene)|uniprotkb:A6NHQ4(identity)|entrezgene/locuslink:100170841(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 rogid:xxrapCjRxgY22pLac2F4zSS2bvk9606 intact-crc:6BD01B3974721D6A|rigid:Qxs+dn+UPmun8pYcqT2ZdMAvuQ8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15022 uniprotkb:O75530 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836162|imex:IM-21659-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:Q15022(identity)|entrezgene/locuslink:23512(identity) refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:O75530(identity)|entrezgene/locuslink:8726(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 intact-crc:6BD01B3974721D6A|rigid:Qxs+dn+UPmun8pYcqT2ZdMAvuQ8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15022 uniprotkb:Q92833 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 intact:EBI-1222720|uniprotkb:Q5U5L5|uniprotkb:A8K9Z6|uniprotkb:B7Z5S5|uniprotkb:Q86X63|uniprotkb:B7Z8L0|ensembl:ENSP00000341280 psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:jard2_human(display_long)|uniprotkb:JARID2(gene name)|psi-mi:JARID2(display_short)|uniprotkb:JMJ(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836162|imex:IM-21659-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:Q15022(identity)|entrezgene/locuslink:23512(identity) refseq:NP_004964.2|refseq:NP_001253969.1|refseq:XP_005249146.1|refseq:XP_016866323.1|refseq:XP_016866324.1|dip:DIP-45494N|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR036431|mint:Q92833|rcsb pdb:5HYN|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000008083(gene)|ensembl:ENST00000341776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007417"(central nervous system development)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0034721"(histone H3-K4 demethylation, trimethyl-H3-K4-specific)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|uniprotkb:Q92833(identity)|entrezgene/locuslink:3720(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 rogid:G/oMY7WdV7UyQwfT4MOZyET2fS89606 intact-crc:6BD01B3974721D6A|rigid:Qxs+dn+UPmun8pYcqT2ZdMAvuQ8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15022 uniprotkb:Q15910 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836162|imex:IM-21659-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:Q15022(identity)|entrezgene/locuslink:23512(identity) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N|uniprotkb:Q15910(identity)|entrezgene/locuslink:2146(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 intact-crc:6BD01B3974721D6A|rigid:Qxs+dn+UPmun8pYcqT2ZdMAvuQ8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15022 uniprotkb:O43189 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 intact:EBI-530034|uniprotkb:B1AZX2|uniprotkb:B1AZX3|uniprotkb:O60929|uniprotkb:Q96KM7|uniprotkb:Q5SU07|uniprotkb:Q5SU08|ensembl:ENSP00000363640|ensembl:ENSP00000391901|ensembl:ENSP00000407295 psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:phf1_human(display_long)|uniprotkb:PCL1(gene name synonym)|uniprotkb:Polycomb-like protein 1(gene name synonym)|uniprotkb:PHF1(gene name)|psi-mi:PHF1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836162|imex:IM-21659-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:Q15022(identity)|entrezgene/locuslink:23512(identity) refseq:XP_011512964.1|refseq:NP_002627.1|refseq:NP_077084.1|ensembl:ENSG00000112511(gene)|ensembl:ENSG00000225553(gene)|ensembl:ENST00000374516(transcript)|ensembl:ENST00000427869(transcript)|ensembl:ENST00000454914(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR031202|interpro:IPR040477|mint:O43189|rcsb pdb:2E5P|rcsb pdb:2M0O|rcsb pdb:4HCZ|rcsb pdb:5XFN|rcsb pdb:5XFO|rcsb pdb:5XFP|rcsb pdb:6WAT|rcsb pdb:6WAV|reactome:R-HSA-212300|dip:DIP-34001N|uniprotkb:O43189(identity)|entrezgene/locuslink:5252(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 rogid:8n8g2LqzuOQb8cFC7tE1j/xBvkI9606 intact-crc:6BD01B3974721D6A|rigid:Qxs+dn+UPmun8pYcqT2ZdMAvuQ8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15022 uniprotkb:Q1XH10 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 intact:EBI-8832973|uniprotkb:Q6ZMX4|uniprotkb:Q8N3C3|uniprotkb:B1ANA5|uniprotkb:E9PAX1|uniprotkb:F5H7M0|ensembl:ENSP00000410041 psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:skda1_human(display_long)|uniprotkb:C10orf140(gene name synonym)|uniprotkb:DLN1(gene name synonym)|uniprotkb:Protein DLN-1(gene name synonym)|uniprotkb:SKIDA1(gene name)|psi-mi:SKIDA1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836162|imex:IM-21659-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:Q15022(identity)|entrezgene/locuslink:23512(identity) refseq:XP_011517782.1|refseq:XP_016871714.1|refseq:XP_016871715.1|refseq:NP_997254.3|refseq:XP_005252507.1|ensembl:ENSG00000180592(gene)|ensembl:ENST00000449193(transcript)|interpro:IPR003380(Transforming protein Ski)|interpro:IPR009061(Putative DNA binding)|interpro:IPR027971|interpro:IPR037000|uniprotkb:Q1XH10(identity)|entrezgene/locuslink:387640(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 rogid:rM6nHmdZz8+n4wjkl/DUhrUeYXE9606 intact-crc:6BD01B3974721D6A|rigid:Qxs+dn+UPmun8pYcqT2ZdMAvuQ8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15022 uniprotkb:Q5T6S3 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 intact:EBI-2339674|uniprotkb:Q6N038|uniprotkb:Q32NF2|uniprotkb:Q8TBL6|uniprotkb:Q5T6S4|uniprotkb:Q9UFS9|ensembl:ENSP00000363003 psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:phf19_human(display_long)|uniprotkb:PHF19(gene name)|psi-mi:PHF19(display_short)|uniprotkb:PCL3(gene name synonym)|uniprotkb:Polycomb-like protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836162|imex:IM-21659-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:Q15022(identity)|entrezgene/locuslink:23512(identity) refseq:XP_011516811.1|refseq:NP_001009936.1|refseq:NP_056466.1|refseq:NP_001273769.1|refseq:NP_001273772.1|refseq:XP_005251963.1|refseq:XP_016870101.1|ensembl:ENSG00000119403(gene)|ensembl:ENST00000373896(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042017|mint:Q5T6S3|rcsb pdb:2E5Q|rcsb pdb:4BD3|rcsb pdb:6NQ3|rcsb pdb:6WAU|reactome:R-HSA-212300|uniprotkb:Q5T6S3(identity)|entrezgene/locuslink:26147(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 rogid:K4sKpUT1htSiigJaEoGyDjvkWqc9606 intact-crc:6BD01B3974721D6A|rigid:Qxs+dn+UPmun8pYcqT2ZdMAvuQ8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15022 uniprotkb:Q92800 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 intact:EBI-8830732|uniprotkb:B4E3R7|uniprotkb:O43287|uniprotkb:A6NCH6|uniprotkb:Q14459|uniprotkb:Q53XP3|uniprotkb:B4DSS2|uniprotkb:B4DIJ1|uniprotkb:B4DIZ7|ensembl:ENSP00000404658|ensembl:ENSP00000466924 psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:ezh1_human(display_long)|uniprotkb:ENX-2(gene name synonym)|uniprotkb:Enhancer of zeste homolog 1(gene name synonym)|uniprotkb:KIAA0388(gene name synonym)|uniprotkb:EZH1(gene name)|psi-mi:EZH1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836162|imex:IM-21659-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421|uniprotkb:Q15022(identity)|entrezgene/locuslink:23512(identity) refseq:NP_001308008.1|refseq:NP_001308010.1|refseq:NP_001308011.1|refseq:NP_001982.2|dip:DIP-58580N|ensembl:ENSG00000108799(gene)|ensembl:ENST00000428826(transcript)|ensembl:ENST00000592743(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0021766"(hippocampus development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0031507"(heterochromatin assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR021654|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR032926|interpro:IPR041343|interpro:IPR041355|interpro:IPR044438|mint:Q92800|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|uniprotkb:Q92800(identity)|entrezgene/locuslink:2145(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 rogid:qp3eqBCgiaoA6VSSyqpW1d9YKN49606 intact-crc:6BD01B3974721D6A|rigid:Qxs+dn+UPmun8pYcqT2ZdMAvuQ8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:D6RGH6 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-3954372|uniprotkb:C9JGY3|uniprotkb:D6R920|uniprotkb:F8KGQ8|ensembl:ENSP00000426359 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:mcin_human(display_long)|uniprotkb:MCIDAS(gene name)|psi-mi:MCIDAS(display_short)|uniprotkb:IDAS(gene name synonym)|uniprotkb:MCI(gene name synonym)|uniprotkb:MCIN(gene name synonym)|uniprotkb:Multiciliate differentiation and DNA synthesis-associated cell cycle protein(gene name synonym)|uniprotkb:Protein Idas(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) refseq:NP_001177716.1|ensembl:ENSG00000234602(gene)|ensembl:ENST00000513312(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060271"(cilium assembly)|go:"GO:0098534"(centriole assembly)|go:"GO:1902017"(regulation of cilium assembly)|go:"GO:1903251"(multi-ciliated epithelial cell differentiation)|interpro:IPR022786|interpro:IPR029699|rcsb pdb:4BRY|go:"GO:0008156"(negative regulation of DNA replication)|uniprotkb:D6RGH6(identity)|entrezgene/locuslink:345643(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:h8n9vYIYeg+800g51izqTj9zZ0c9606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:Q13185 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:Q92769 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-301821|uniprotkb:Q5SRI8|uniprotkb:Q5SZ86|uniprotkb:Q8NEH4|uniprotkb:B4DL58|ensembl:ENSP00000430432|uniprotkb:E1P561|uniprotkb:B3KRS5 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:hdac2_human(display_long)|uniprotkb:HDAC2(gene name)|psi-mi:HDAC2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035094"(response to nicotine)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042220"(response to cocaine)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q92769|rcsb pdb:3MAX|rcsb pdb:4LXZ|rcsb pdb:4LY1|rcsb pdb:5IWG|rcsb pdb:5IX0|rcsb pdb:6G3O|rcsb pdb:6WBW|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000196591(gene)|ensembl:ENST00000519065(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|rcsb pdb:6WHN|rcsb pdb:6WHO|rcsb pdb:6WHQ|rcsb pdb:6WHZ|rcsb pdb:6WI3|rcsb pdb:6XDM|rcsb pdb:6XEB|rcsb pdb:6XEC|rcsb pdb:7KBG|rcsb pdb:7KBH|rcsb pdb:7LTG|rcsb pdb:7LTK|rcsb pdb:7LTL|reactome:R-HSA-193670|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9615017|reactome:R-HSA-9619665|reactome:R-HSA-9679191|reactome:R-HSA-983231|rcsb pdb:6WBZ|refseq:NP_001518.3|dip:DIP-24220N|refseq:XP_011534090.1|refseq:XP_016866288.1|uniprotkb:Q92769(identity)|entrezgene/locuslink:3066(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:K4PpGz9E9/TrQZsgvrJuc+uYCn89606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:O43823 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-1237481|ensembl:ENSP00000269701 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:akap8_human(display_long)|uniprotkb:AKAP8(gene name)|psi-mi:AKAP8(display_short)|uniprotkb:AKAP95(gene name synonym)|uniprotkb:A-kinase anchor protein 95 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) refseq:NP_005849.1|dip:DIP-38194N|ensembl:ENSG00000105127(gene)|ensembl:ENST00000269701(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001939"(female pronucleus)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0033127"(regulation of histone phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044839"(cell cycle G2/M phase transition)|go:"GO:0045087"(innate immune response)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|interpro:IPR007071("A-kinase anchoring protein 95 (AKAP95)")|interpro:IPR034736|mint:O43823|go:"GO:0051059"(NF-kappaB binding)|uniprotkb:O43823(identity)|entrezgene/locuslink:10270(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:VtRlGSvkRqrzAcnq2Fj6fToZifY9606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:O00716 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|uniprotkb:O00716(identity)|entrezgene/locuslink:1871(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:Q9BQE3 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1|uniprotkb:Q9BQE3(identity)|entrezgene/locuslink:84790(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:Q9NX08 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-725694|uniprotkb:Q8WUR4|uniprotkb:Q9HC15|ensembl:ENSP00000370984 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:comd8_human(display_long)|uniprotkb:COMMD8(gene name)|psi-mi:COMMD8(display_short)|uniprotkb:MDS022(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) refseq:NP_060315.1|ensembl:ENSG00000169019(gene)|ensembl:ENST00000381571(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR017920|mint:Q9NX08|reactome:R-HSA-8951664|refseq:NP_001316597.1|uniprotkb:Q9NX08(identity)|entrezgene/locuslink:54951(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:m3HKrdrtTRNJyCfMBLOZCaZRexg9606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:P06400 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-491274|uniprotkb:P78499|uniprotkb:Q5VW46|uniprotkb:Q8IZL4|uniprotkb:A8K5E3|ensembl:ENSP00000267163 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:rb_human(display_long)|uniprotkb:pRb(gene name synonym)|uniprotkb:pp110(gene name synonym)|uniprotkb:p105-Rb(gene name synonym)|uniprotkb:RB1(gene name)|psi-mi:RB1(display_short)|uniprotkb:p110-RB1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) go:"GO:1903055"(positive regulation of extracellular matrix organization)|refseq:NP_000312.2|go:"GO:1904028"(positive regulation of collagen fibril organization)|go:"GO:1904761"(negative regulation of myofibroblast differentiation)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR036915|mint:P06400|rcsb pdb:1AD6|rcsb pdb:1GH6|rcsb pdb:1GUX|rcsb pdb:1H25|rcsb pdb:1N4M|rcsb pdb:1O9K|rcsb pdb:1PJM|rcsb pdb:2AZE|rcsb pdb:2QDJ|rcsb pdb:2R7G|rcsb pdb:3N5U|rcsb pdb:3POM|rcsb pdb:4CRI|rcsb pdb:4ELJ|rcsb pdb:4ELL|reactome:R-HSA-113501|reactome:R-HSA-174178|reactome:R-HSA-2299718|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-69200|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8940973|reactome:R-HSA-9661069|reactome:R-HSA-9661070|reactome:R-HSA-9682706|reactome:R-HSA-9687136|reactome:R-HSA-9694686|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016605"(PML body)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0019900"(kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0031175"(neuron projection development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034088"(maintenance of mitotic sister chromatid cohesion)|go:"GO:0034349"(glial cell apoptotic process)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042551"(neuron maturation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0071922"(regulation of cohesin loading)|go:"GO:0071930"(negative regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0090230"(regulation of centromere complex assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902948"(negative regulation of tau-protein kinase activity)|ensembl:ENSG00000139687(gene)|ensembl:ENST00000267163(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|dip:DIP-582N|uniprotkb:P06400(identity)|entrezgene/locuslink:5925(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:xidCNX96KlQzu160polvT61k4Zw9606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:P16615 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-358933|uniprotkb:P16614|uniprotkb:A6NDN7|uniprotkb:B4DF05|uniprotkb:Q86VJ2|ensembl:ENSP00000440045 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:at2a2_human(display_long)|uniprotkb:ATP2A2(gene name)|psi-mi:ATP2A2(display_short)|uniprotkb:ATP2B(gene name synonym)|uniprotkb:Calcium pump 2(gene name synonym)|uniprotkb:Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform(gene name synonym)|uniprotkb:"Endoplasmic reticulum class 1/2 Ca(2+) ATPase"(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) refseq:NP_001672.1|refseq:NP_733765.1|refseq:XP_011536704.1|ensembl:ENSG00000174437(gene)|ensembl:ENST00000539276(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006984"(ER-nucleus signaling pathway)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008544"(epidermis development)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014801"(longitudinal sarcoplasmic reticulum)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016020"(membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019899"(enzyme binding)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031775"(lutropin-choriogonadotropic hormone receptor binding)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032470"(positive regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0061831"(apical ectoplasmic specialization)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086039"(P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential)|go:"GO:0090534"(calcium ion-transporting ATPase complex)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:0120025"(plasma membrane bounded cell projection)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1903233"(regulation of calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:1903515"(calcium ion transport from cytosol to endoplasmic reticulum)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1990036"(calcium ion import into sarcoplasmic reticulum)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005782(Calcium ATPase)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P16615|rcsb pdb:5ZTF|rcsb pdb:6JJU|rcsb pdb:6LLE|rcsb pdb:6LLY|rcsb pdb:6LN5|rcsb pdb:6LN6|rcsb pdb:6LN7|rcsb pdb:6LN8|rcsb pdb:6LN9|rcsb pdb:7BT2|reactome:R-HSA-1912420|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|go:"GO:0000045"(autophagosome assembly)|refseq:XP_005253945.1|dip:DIP-33868N|uniprotkb:P16615(identity)|entrezgene/locuslink:488(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:QlJZW2fprLYahKUrHDOVs28kA2w9606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:Q8N668 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-1550112|uniprotkb:Q96GS0|uniprotkb:B4DFQ4|ensembl:ENSP00000308236 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:comd1_human(display_long)|uniprotkb:COMMD1(gene name)|psi-mi:COMMD1(display_short)|uniprotkb:C2orf5(gene name synonym)|uniprotkb:MURR1(gene name synonym)|uniprotkb:Protein Murr1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) refseq:NP_689729.1|ensembl:ENSG00000173163(gene)|ensembl:ENST00000311832(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR017920|interpro:IPR033776|interpro:IPR037351|mint:Q8N668|rcsb pdb:2H2M|reactome:R-HSA-8951664|uniprotkb:Q8N668(identity)|entrezgene/locuslink:150684(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:b4sVuz5jwndjw+8ejRFqOcLRk1I9606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:Q15365 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-946095|uniprotkb:Q13157|uniprotkb:Q14975|ensembl:ENSP00000305556 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:pcbp1_human(display_long)|uniprotkb:PCBP1(gene name)|psi-mi:PCBP1(display_short)|uniprotkb:Alpha-CP1(gene name synonym)|uniprotkb:Nucleic acid-binding protein SUB2.3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) refseq:NP_006187.2|dip:DIP-38136N|ensembl:ENSG00000169564(gene)|ensembl:ENST00000303577(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098847"(sequence-specific single stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15365|rcsb pdb:1WVN|rcsb pdb:1ZTG|rcsb pdb:3VKE|reactome:R-HSA-72163|reactome:R-HSA-72203|uniprotkb:Q15365(identity)|entrezgene/locuslink:5093(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:x72fawo4plQ+ipfqIoREIDHc2bA9606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:P28288 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-80992|ensembl:ENSP00000359233|uniprotkb:Q15271|uniprotkb:Q9H529|uniprotkb:Q6NUN5|uniprotkb:Q96DA3|uniprotkb:D3DT46 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:abcd3_human(display_long)|uniprotkb:ABCD3(gene name)|psi-mi:ABCD3(display_short)|uniprotkb:PMP70(gene name synonym)|uniprotkb:PXMP1(gene name synonym)|uniprotkb:70 kDa peroxisomal membrane protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) ensembl:ENSG00000117528(gene)|ensembl:ENST00000370214(transcript)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0007031"(peroxisome organization)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042493"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|refseq:NP_001116146.1|refseq:NP_002849.1|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005283(Peroxysomal long chain fatty acyl transporter)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|mint:P28288|reactome:R-HSA-1369062|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9603798|uniprotkb:P28288(identity)|entrezgene/locuslink:5825(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:aUTR1BDihIx1JxtsC5V4vmFAwA49606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:Q8IWI9 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-2815196|uniprotkb:E7ENI0|uniprotkb:F5H7K2|uniprotkb:Q9H9N7|uniprotkb:Q9H8R3|uniprotkb:Q9Y4E9|uniprotkb:Q9UG69|intact:EBI-11143500|intact:EBI-10969960|ensembl:ENSP00000219905|uniprotkb:B9EGR5 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:mgap_human(display_long)|uniprotkb:MGA(gene name)|psi-mi:MGA(display_short)|uniprotkb:KIAA0518(gene name synonym)|uniprotkb:MAD5(gene name synonym)|uniprotkb:MAX dimerization protein 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) refseq:NP_001074010.2|ensembl:ENSP00000219905|ensembl:ENST00000566586|ensembl:ENSP00000456141|ensembl:ENSG00000174197(gene)|ensembl:ENST00000219905(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR018186|interpro:IPR032060|interpro:IPR036638|interpro:IPR036960|interpro:IPR037935|mint:Q8IWI9|reactome:R-HSA-8953750|refseq:NP_001157745.1|dip:DIP-57615N|uniprotkb:Q8IWI9(identity)|entrezgene/locuslink:23269(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:P4lo9EteCvikQQk5kyVkcobitLU9606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:P18077 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-353383|uniprotkb:Q08ES9|uniprotkb:Q9BVN7|ensembl:ENSP00000393393|ensembl:ENSP00000495672 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:rl35a_human(display_long)|uniprotkb:RPL35A(gene name)|psi-mi:RPL35A(display_short)|uniprotkb:Cell growth-inhibiting gene 33 protein(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL33(gene name synonym)|uniprotkb:GIG33(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) refseq:NP_000987.2|refseq:NP_001303240.1|ensembl:ENST00000647248(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001780(Ribosomal protein L35Ae)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR018266|interpro:IPR038661|mint:P18077|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|ensembl:ENSG00000182899(gene)|ensembl:ENST00000448864(transcript)|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|uniprotkb:P18077(identity)|entrezgene/locuslink:6165(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:fnUlL17LsiOp3lSkKNsoYO74IQQ9606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:P05090 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-715495|uniprotkb:Q6IBG6|uniprotkb:B2R579|uniprotkb:D3DNW6|ensembl:ENSP00000345179 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:apod_human(display_long)|uniprotkb:APOD(gene name)|psi-mi:APOD(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) refseq:NP_001638.1|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030425"(dendrite)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048678"(response to axon injury)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0060588"(negative regulation of lipoprotein lipid oxidation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071638"(negative regulation of monocyte chemotactic protein-1 production)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:2000098"(negative regulation of smooth muscle cell-matrix adhesion)|go:"GO:2000405"(negative regulation of T cell migration)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR002969(Apolipoprotein D)|interpro:IPR012674(Calycin)|interpro:IPR022271|interpro:IPR022272|interpro:IPR026222|mint:P05090|rcsb pdb:2APD|rcsb pdb:2HZQ|rcsb pdb:2HZR|reactome:R-HSA-804914|reactome:R-HSA-9029569|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0015485"(cholesterol binding)|ensembl:ENSG00000189058(gene)|ensembl:ENST00000343267(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001525"(angiogenesis)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|uniprotkb:P05090(identity)|entrezgene/locuslink:347(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:eD7+u5/ZQ5vntlwrq6itkhCxZJU9606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:Q16254 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-448943|uniprotkb:A6NGR8|uniprotkb:Q12991|uniprotkb:Q15328|uniprotkb:B5BU56|ensembl:ENSP00000368686 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:e2f4_human(display_long)|uniprotkb:E2F4(gene name)|psi-mi:E2F4(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) refseq:NP_001941.2|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-2173796|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|ensembl:ENSG00000205250(gene)|ensembl:ENST00000379378(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0008015"(blood circulation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0098534"(centriole assembly)|go:"GO:1903251"(multi-ciliated epithelial cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR028312|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:Q16254|rcsb pdb:1CF7|rcsb pdb:5TUU|reactome:R-HSA-1362277|dip:DIP-24185N|uniprotkb:Q16254(identity)|entrezgene/locuslink:1874(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:t0tCW85omHMU3lVgYWEXNeX1sTI9606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:O75496 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-371669|uniprotkb:Q9H1Z1|uniprotkb:B3KMM8|ensembl:ENSP00000230056|ensembl:ENSP00000348902|ensembl:ENSP00000477506 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:gemi_human(display_long)|uniprotkb:GMNN(gene name)|psi-mi:GMNN(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) refseq:NP_056979.1|refseq:NP_001238918.1|refseq:NP_001238919.1|refseq:NP_001238920.1|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071163"(DNA replication preinitiation complex assembly)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000104"(negative regulation of DNA-dependent DNA replication)|interpro:IPR022786|interpro:IPR029697|mint:O75496|rcsb pdb:1T6F|rcsb pdb:1UII|rcsb pdb:2LP0|rcsb pdb:2WVR|rcsb pdb:4BRY|reactome:R-HSA-68827|go:"GO:0009887"(animal organ morphogenesis)|reactome:R-HSA-68962|refseq:XP_005249216.1|ensembl:ENSG00000112312(gene)|ensembl:ENST00000230056(transcript)|ensembl:ENST00000356509(transcript)|ensembl:ENST00000620958(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0008156"(negative regulation of DNA replication)|dip:DIP-31088N|uniprotkb:O75496(identity)|entrezgene/locuslink:51053(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:4jWHqSy3+J1JqSU+kNTTYmeYjF49606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:Q96IX5 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-954033|ensembl:ENSP00000311245|ensembl:ENSP00000337705|ensembl:ENSP00000358826|ensembl:ENSP00000358830|ensembl:ENSP00000358840|uniprotkb:B2R4N2|uniprotkb:D3DR92 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:atpmk_human(display_long)|uniprotkb:ATP5MK(gene name)|psi-mi:ATP5MK(display_short)|uniprotkb:ATP synthase membrane subunit DAPIT, mitochondrial(gene name synonym)|uniprotkb:ATP5MD(gene name synonym)|uniprotkb:DAPIT(gene name synonym)|uniprotkb:Diabetes-associated protein in insulin-sensitive tissues(gene name synonym)|uniprotkb:HCV F-transactivated protein 2(gene name synonym)|uniprotkb:HCVFTP2(gene name synonym)|uniprotkb:USMG5(gene name synonym)|uniprotkb:Up-regulated during skeletal muscle growth protein 5(gene name synonym)|uniprotkb:PD04912(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) ensembl:ENSG00000173915(gene)|ensembl:ENST00000309579(transcript)|ensembl:ENST00000337003(transcript)|ensembl:ENST00000369811(transcript)|ensembl:ENST00000369815(transcript)|ensembl:ENST00000369825(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR009125(DAPIT)|mint:Q96IX5|refseq:NP_001193355.1|refseq:NP_001193356.1|refseq:NP_116136.1|uniprotkb:Q96IX5(identity)|entrezgene/locuslink:84833(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:7ClNWlgeH39kD7E6oiQdkuj7Hag9606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:O75461 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|entrezgene/locuslink:1876(identity)|uniprotkb:O75461(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:Q9BSD7 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-2689235|ensembl:ENSP00000355587 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:ntpcr_human(display_long)|uniprotkb:Nucleoside triphosphate phosphohydrolase(gene name synonym)|uniprotkb:NTPCR(gene name)|psi-mi:NTPCR(display_short)|uniprotkb:C1orf57(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) refseq:NP_115700.1|interpro:IPR027417|mint:Q9BSD7|rcsb pdb:2I3B|ensembl:ENSG00000135778(gene)|ensembl:ENST00000366628(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0016020"(membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004948(Protein of unknown function DUF265)|refseq:NP_001316382.1|uniprotkb:Q9BSD7(identity)|entrezgene/locuslink:84284(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:tJoP+XQzoa4urq6g1rdZhMWO49g9606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:Q06587 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:P61244 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750|uniprotkb:P61244(identity)|entrezgene/locuslink:4149(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:I5d1d/zT353OsLios95yEITNoWU9606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:Q7Z4G1 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-1550081|uniprotkb:A6NF28|uniprotkb:Q5TBK4|uniprotkb:B7ZLN0|ensembl:ENSP00000366841|ensembl:ENSP00000506987 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:comd6_human(display_long)|uniprotkb:COMMD6(gene name)|psi-mi:COMMD6(display_short)|uniprotkb:MSTP076(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) refseq:NP_987091.1|refseq:NP_987093.1|ensembl:ENSG00000188243(gene)|ensembl:ENST00000377615(transcript)|ensembl:ENST00000682242(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0051059"(NF-kappaB binding)|interpro:IPR017920|reactome:R-HSA-8951664|uniprotkb:Q7Z4G1(identity)|entrezgene/locuslink:170622(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:73rTIbUABTRqe9OabTgdQ1QvZ7A9606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:Q13547 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-301834|uniprotkb:Q92534|ensembl:ENSP00000362649 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:hdac1_human(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:RPD3L1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) ensembl:ENSG00000116478(gene)|ensembl:ENST00000373548(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007492"(endoderm development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031000"(response to caffeine)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043044"|go:"GO:0019213"(deacetylase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900221"(regulation of amyloid-beta clearance)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q13547|rcsb pdb:1TYI|rcsb pdb:4BKX|rcsb pdb:5ICN|rcsb pdb:6Z2J|rcsb pdb:6Z2K|rcsb pdb:7AO8|rcsb pdb:7AO9|rcsb pdb:7AOA|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-193670|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-3769402|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-4641265|reactome:R-HSA-6804758|reactome:R-HSA-69205|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9022538|reactome:R-HSA-9022692|go:"GO:0017053"(transcription repressor complex)|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9615017|reactome:R-HSA-9679191|reactome:R-HSA-983231|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:NP_004955.2|dip:DIP-24184N|uniprotkb:Q13547(identity)|entrezgene/locuslink:3065(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:RP+yIBWH55NgoPTY1nKXqeJL/xY9606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:P61964 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|entrezgene/locuslink:11091(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:P50990 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N|uniprotkb:P50990(identity)|entrezgene/locuslink:10694(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:Q969R5 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750|uniprotkb:Q969R5(identity)|entrezgene/locuslink:83746(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:P00367 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-356544|uniprotkb:Q5TBU3|ensembl:ENSP00000277865|uniprotkb:B3KV55|uniprotkb:B4DGN5 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:dhe3_human(display_long)|uniprotkb:GLUD1(gene name)|psi-mi:GLUD1(display_short)|uniprotkb:GLUD(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) ensembl:ENSG00000148672(gene)|ensembl:ENST00000277865(transcript)|go:"GO:0004352"("glutamate dehydrogenase (NAD+) activity")|go:"GO:0004353"("glutamate dehydrogenase [NAD(P)+] activity")|go:"GO:0004354"("glutamate dehydrogenase (NADP+) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0042802"(identical protein binding)|refseq:NP_005262.1|refseq:NP_001305829.1|refseq:NP_001305830.1|refseq:NP_001305831.1|refseq:NP_001305833.1|refseq:NP_001305834.1|refseq:NP_001305835.1|go:"GO:0043531"(ADP binding)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070728"(leucine binding)|go:"GO:0072350"(tricarboxylic acid metabolic process)|interpro:IPR006095(Glutamate/phenylalanine/leucine/valine dehydrogenase)|interpro:IPR006096(Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal)|interpro:IPR006097(Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation region)|interpro:IPR033524|interpro:IPR033922|interpro:IPR036291|mint:P00367|rcsb pdb:1L1F|rcsb pdb:1NR1|rcsb pdb:6DQG|reactome:R-HSA-2151201|reactome:R-HSA-8964539|uniprotkb:P00367(identity)|entrezgene/locuslink:2746(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:rWYi7otiOLlUvfEl7Vy6ELkY+BM9606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:P48643 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N|uniprotkb:P48643(identity)|entrezgene/locuslink:22948(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:Q01094 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-448924|uniprotkb:Q13143|uniprotkb:Q92768|ensembl:ENSP00000345571 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:e2f1_human(display_long)|uniprotkb:Retinoblastoma-associated protein 1(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 3(gene name synonym)|uniprotkb:PBR3(gene name synonym)|uniprotkb:E2F1(gene name)|psi-mi:E2F1(display_short)|uniprotkb:RBBP3(gene name synonym)|uniprotkb:pRB-binding protein E2F-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) refseq:NP_005216.1|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071930"(negative regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990086"(lens fiber cell apoptotic process)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030900"(forebrain development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043276"(anoikis)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048255"(mRNA stabilization)|ensembl:ENSG00000101412(gene)|ensembl:ENST00000343380(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804116|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:Q01094|rcsb pdb:1H24|rcsb pdb:1O9K|rcsb pdb:2AZE|rcsb pdb:5M9N|rcsb pdb:5M9O|rcsb pdb:6G0P|rcsb pdb:6ULS|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1912408|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9616222|reactome:R-HSA-9661069|dip:DIP-24227N|uniprotkb:Q01094(identity)|entrezgene/locuslink:1869(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:vPNenpmxyXpHjMzUID54cwMFk+Y9606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:Q14257 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-356710|uniprotkb:A8MTG6|uniprotkb:Q53XN8|ensembl:ENSP00000378349|uniprotkb:F8WCY5 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:rcn2_human(display_long)|uniprotkb:RCN2(gene name)|psi-mi:RCN2(display_short)|uniprotkb:ERC55(gene name synonym)|uniprotkb:Calcium-binding protein ERC-55(gene name synonym)|uniprotkb:E6-binding protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) refseq:NP_002893.1|ensembl:ENST00000394885(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|ensembl:ENSG00000117906(gene)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q14257|refseq:NP_001258766.1|uniprotkb:Q14257(identity)|entrezgene/locuslink:5955(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:99ru/7eYUvZ5xdb+x4inbib3PP89606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:Q86VP6 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-456077|uniprotkb:O94918|uniprotkb:Q6PIY4|uniprotkb:Q8NDJ4|uniprotkb:Q96JZ9|uniprotkb:Q96T19|uniprotkb:Q9BTC4|uniprotkb:Q9H0G2|uniprotkb:Q9P0H7|uniprotkb:Q9UF85|uniprotkb:B2RAU3|ensembl:ENSP00000442318 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:cand1_human(display_long)|uniprotkb:KIAA0829(gene name synonym)|uniprotkb:TIP120(gene name synonym)|uniprotkb:TIP120A(gene name synonym)|uniprotkb:Cullin-associated and neddylation-dissociated protein 1(gene name synonym)|uniprotkb:p120 CAND1(gene name synonym)|uniprotkb:TBP-interacting protein of 120 kDa A(gene name synonym)|uniprotkb:CAND1(gene name)|psi-mi:CAND1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) refseq:NP_060918.2|dip:DIP-31608N|ensembl:ENSG00000111530(gene)|ensembl:ENST00000545606(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010265"(SCF complex assembly)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR013932("TATA-binding protein interacting (TIP20)")|interpro:IPR039852|mint:Q86VP6|rcsb pdb:1U6G|rcsb pdb:4A0C|reactome:R-HSA-6798695|reactome:R-HSA-8951664|reactome:R-HSA-917937|interpro:IPR016024(Armadillo-type fold)|uniprotkb:Q86VP6(identity)|entrezgene/locuslink:55832(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:2lBY8xJXlGZL+xyo/dyB2WzuNqs9606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:Q9H0A8 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-1550064|uniprotkb:Q7L637|uniprotkb:Q9NX43|uniprotkb:B2RBN4|uniprotkb:H3BUL2|ensembl:ENSP00000267935|ensembl:ENSP00000433662 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:comd4_human(display_long)|uniprotkb:COMMD4(gene name)|psi-mi:COMMD4(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) refseq:NP_001271306.1|refseq:NP_060298.2|refseq:NP_001271307.1|ensembl:ENSG00000140365(gene)|ensembl:ENST00000267935(transcript)|ensembl:ENST00000480484(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR017920|interpro:IPR037356|reactome:R-HSA-8951664|uniprotkb:Q9H0A8(identity)|entrezgene/locuslink:54939(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:v1pkDNc18f7sZM/89Gv0bho9GN89606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:Q99496 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|entrezgene/locuslink:6045(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:Q9UBX3 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-750394|uniprotkb:Q96BA1|uniprotkb:Q96IP1|uniprotkb:Q542Z3|ensembl:ENSP00000345580 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:dic_human(display_long)|uniprotkb:Solute carrier family 25 member 10(gene name synonym)|uniprotkb:SLC25A10(gene name)|psi-mi:SLC25A10(display_short)|uniprotkb:DIC(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) refseq:NP_036272.2|refseq:NP_001257817.1|refseq:NP_001257882.1|go:"GO:0015131"(oxaloacetate transmembrane transporter activity)|go:"GO:0015140"(malate transmembrane transporter activity)|go:"GO:0015141"(succinate transmembrane transporter activity)|go:"GO:0015297"(antiporter activity)|go:"GO:0015709"(thiosulfate transport)|go:"GO:0015729"(oxaloacetate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0070221"("sulfide oxidation, using sulfide:quinone oxidoreductase")|go:"GO:0071422"(succinate transmembrane transport)|ensembl:ENSG00000183048(gene)|ensembl:ENST00000350690(transcript)|go:"GO:0005310"(dicarboxylic acid transmembrane transporter activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006811"(ion transport)|go:"GO:0006835"(dicarboxylic acid transport)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0008272"(sulfate transport)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015117"(thiosulfate transmembrane transporter activity)|reactome:R-HSA-70263|go:"GO:0071423"(malate transmembrane transport)|interpro:IPR002030(Mitochondrial brown fat uncoupling protein)|interpro:IPR018108|interpro:IPR023395|mint:Q9UBX3|reactome:R-HSA-1614517|reactome:R-HSA-428643|uniprotkb:Q9UBX3(identity)|entrezgene/locuslink:1468(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:Z9a7UxJbOLZqoCyz+5L+mbkXFqk9606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:Q14209 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-718476|uniprotkb:Q7Z6H1|uniprotkb:B2R9W1|ensembl:ENSP00000355249|ensembl:ENSP00000489612 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:e2f2_human(display_long)|uniprotkb:E2F2(gene name)|psi-mi:E2F2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) refseq:NP_004082.1|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990086"(lens fiber cell apoptotic process)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:Q14209|rcsb pdb:1N4M|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-69231|reactome:R-HSA-9661069|ensembl:ENSG00000007968(gene)|ensembl:ENSG00000282899(gene)|ensembl:ENST00000361729(transcript)|ensembl:ENST00000634683(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|dip:DIP-258N|uniprotkb:Q14209(identity)|entrezgene/locuslink:1870(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:mTyyEcashAWBpjb0viYJv5OiREY9606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:P61204 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-641535|uniprotkb:P16587|uniprotkb:A8K6G8|ensembl:ENSP00000256682|ensembl:ENSP00000438510|uniprotkb:B7ZB63 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:arf3_human(display_long)|uniprotkb:ARF3(gene name)|psi-mi:ARF3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) refseq:NP_001650.1|ensembl:ENSG00000134287(gene)|ensembl:ENST00000256682(transcript)|ensembl:ENST00000541959(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P61204|rcsb pdb:6II6|reactome:R-HSA-1660514|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:XP_005268913.1|uniprotkb:P61204(identity)|entrezgene/locuslink:377(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:np09WjdbXRu9vgMbiXn9EA3ExqA9606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:Q13263 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-78139|uniprotkb:O00677|ensembl:ENSP00000253024|uniprotkb:Q7Z632|uniprotkb:Q93040|uniprotkb:Q96IM1 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:tif1b_human(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6QAJ|rcsb pdb:6QU1|reactome:R-HSA-212436|reactome:R-HSA-3899300|reactome:R-HSA-9609690|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q13263|rcsb pdb:1FP0|rcsb pdb:2RO1|rcsb pdb:2YVR|rcsb pdb:6H3A|rcsb pdb:6I9H|refseq:NP_005753.1|dip:DIP-30891N|uniprotkb:Q13263(identity)|entrezgene/locuslink:10155(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:O94905 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-4400770|uniprotkb:A0JLQ1|uniprotkb:A8K5S9|uniprotkb:B4DM38|uniprotkb:D3DSW0|uniprotkb:Q6NW21|uniprotkb:Q86VS6|uniprotkb:Q86W49|ensembl:ENSP00000428112 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:erln2_human(display_long)|uniprotkb:ERLIN2(gene name)|psi-mi:ERLIN2(display_short)|uniprotkb:C8orf2(gene name synonym)|uniprotkb:SPFH2(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 2(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2(gene name synonym)|uniprotkb:UNQ2441/PRO5003/PRO9924(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) refseq:NP_001003790.1|refseq:NP_001003791.1|refseq:NP_009106.1|refseq:XP_016868489.1|refseq:XP_005273449.1|ensembl:ENSG00000147475(gene)|ensembl:ENST00000519638(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045121"(membrane raft)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O94905|reactome:R-HSA-382556|reactome:R-HSA-5655302|reactome:R-HSA-5678895|reactome:R-HSA-8853336|uniprotkb:O94905(identity)|entrezgene/locuslink:11160(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:Evjg3G0FFeQ499BNlJxpK6t8to89606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:Q9BYE7 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:Q15329 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-1389773|uniprotkb:Q16601|uniprotkb:Q92756|uniprotkb:E9PBN9|ensembl:ENSP00000398124 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:e2f5_human(display_long)|uniprotkb:E2F5(gene name)|psi-mi:E2F5(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) refseq:NP_001077057.1|refseq:NP_001077058.1|refseq:NP_001942.2|dip:DIP-24229N|ensembl:ENSG00000133740(gene)|ensembl:ENST00000416274(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001650"(fibrillar center)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030030"(cell projection organization)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR028316|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:Q15329|rcsb pdb:5TUV|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-2173796|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|uniprotkb:Q15329(identity)|entrezgene/locuslink:1875(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:M9xU+a14lZDS6cyMt8LF+uMMH8k9606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:O95218 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-1051583|intact:EBI-1642120|intact:EBI-1163882|intact:EBI-1166395|uniprotkb:Q53GS3|uniprotkb:Q59F92|uniprotkb:Q5VV33|uniprotkb:Q8IXN6|uniprotkb:Q9UP63|uniprotkb:Q5VV34|uniprotkb:D3DQ75|ensembl:ENSP00000359958 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:zrab2_human(display_long)|uniprotkb:ZRANB2(gene name)|psi-mi:ZRANB2(display_short)|uniprotkb:ZIS(gene name synonym)|uniprotkb:ZNF265(gene name synonym)|uniprotkb:Zinc finger protein 265(gene name synonym)|uniprotkb:Zinc finger, splicing(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836223|imex:IM-21659-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|ddbj/embl/genbank:BC011685(identity)|entrezgene/locuslink:7027(identity) refseq:NP_005446.2|refseq:NP_976225.1|ensembl:ENSG00000132485(gene)|ensembl:ENST00000370920(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR017337(Uncharacterised conserved protein UCP037956, zinc finger Ran-binding)|interpro:IPR036443|mint:O95218|rcsb pdb:1N0Z|rcsb pdb:2K1P|rcsb pdb:3G9Y|uniprotkb:O95218(identity)|entrezgene/locuslink:9406(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:NSsZyRDwY5bF3I5OGvd1jGYTijY9606 intact-crc:9EF99F3983BE45A6|rigid:toLeUZTvEBUtjdFQuf5qxqmYejk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14669 uniprotkb:O60684 intact:EBI-308443|uniprotkb:Q15644|ensembl:ENSP00000283943|uniprotkb:D4HL82|uniprotkb:Q14CA3|uniprotkb:Q14CF1|uniprotkb:Q53R87|uniprotkb:Q53TE7 intact:EBI-359923|uniprotkb:Q5VVU3|uniprotkb:B2RDC7|ensembl:ENSP00000362728|uniprotkb:D3DPP5 psi-mi:tripc_human(display_long)|uniprotkb:TRIP12(gene name)|psi-mi:TRIP12(display_short)|uniprotkb:Thyroid receptor-interacting protein 12(gene name synonym)|uniprotkb:KIAA0045(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase for Arf(gene name synonym)|uniprotkb:ULF(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase TRIP12(gene name synonym) psi-mi:ima7_human(display_long)|uniprotkb:KPNA6(gene name)|psi-mi:KPNA6(display_short)|uniprotkb:IPOA7(gene name synonym)|uniprotkb:Karyopherin subunit alpha-6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836401|imex:IM-21659-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004229.1|refseq:NP_001271143.1|refseq:NP_001271144.1|refseq:NP_001271145.1|ensembl:ENSG00000153827(gene)|ensembl:ENST00000283943(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016607"(nuclear speck)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR000569(HECT)|interpro:IPR004170(WWE)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR035983|interpro:IPR037197|mint:Q14669|reactome:R-HSA-983168|refseq:NP_001335244.1|refseq:NP_001335245.1|ensembl:ENSP00000283943|ensembl:ENST00000389044|ensembl:ENST00000389045|ensembl:ENSP00000373697|ensembl:ENSP00000373696|dip:DIP-58584N|uniprotkb:Q14669(identity)|entrezgene/locuslink:9320(identity)|ddbj/embl/genbank:BC114556(identity) refseq:NP_036448.1|ensembl:ENSG00000025800(gene)|ensembl:ENST00000373625(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0019079"(viral genome replication)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0043657"(host cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O60684|rcsb pdb:4UAD|dip:DIP-27609N|uniprotkb:O60684(identity)|entrezgene/locuslink:23633(identity) psi-mi:"MI:0469"(intact) caution:This sequence has been withdrawn from Uniprot.|crc64:294A7C063A3332DE - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wzXMKIUEDV4y7YE6PDU+LIPHl7U9606 rogid:3NsSIcE6BHIqYlvfGRolUKD/5uc9606 intact-crc:66EE72D629891156|rigid:uYmi/4i9spIWjsEGUAvsZlc2vvo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14669 uniprotkb:O15131 intact:EBI-308443|uniprotkb:Q15644|ensembl:ENSP00000283943|uniprotkb:D4HL82|uniprotkb:Q14CA3|uniprotkb:Q14CF1|uniprotkb:Q53R87|uniprotkb:Q53TE7 intact:EBI-540602|uniprotkb:Q86X23|uniprotkb:B2RAI5|ensembl:ENSP00000348704|ensembl:ENSP00000357552 psi-mi:tripc_human(display_long)|uniprotkb:TRIP12(gene name)|psi-mi:TRIP12(display_short)|uniprotkb:Thyroid receptor-interacting protein 12(gene name synonym)|uniprotkb:KIAA0045(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase for Arf(gene name synonym)|uniprotkb:ULF(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase TRIP12(gene name synonym) psi-mi:ima6_human(display_long)|uniprotkb:Karyopherin subunit alpha-5(gene name synonym)|uniprotkb:KPNA5(gene name)|psi-mi:KPNA5(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836401|imex:IM-21659-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004229.1|refseq:NP_001271143.1|refseq:NP_001271144.1|refseq:NP_001271145.1|ensembl:ENSG00000153827(gene)|ensembl:ENST00000283943(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016607"(nuclear speck)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR000569(HECT)|interpro:IPR004170(WWE)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR035983|interpro:IPR037197|mint:Q14669|reactome:R-HSA-983168|refseq:NP_001335244.1|refseq:NP_001335245.1|ensembl:ENSP00000283943|ensembl:ENST00000389044|ensembl:ENST00000389045|ensembl:ENSP00000373697|ensembl:ENSP00000373696|dip:DIP-58584N|uniprotkb:Q14669(identity)|entrezgene/locuslink:9320(identity)|ddbj/embl/genbank:BC114556(identity) refseq:NP_002260.2|reactome:R-HSA-1169408|reactome:R-HSA-168276|rcsb pdb:4U2X|ensembl:ENSG00000196911(gene)|ensembl:ENST00000356348(transcript)|ensembl:ENST00000368564(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O15131|refseq:XP_016866328.1|refseq:XP_016866329.1|dip:DIP-33405N|uniprotkb:O15131(identity)|entrezgene/locuslink:3841(identity) psi-mi:"MI:0469"(intact) caution:This sequence has been withdrawn from Uniprot.|crc64:294A7C063A3332DE - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wzXMKIUEDV4y7YE6PDU+LIPHl7U9606 rogid:ixGSmHZKndxkY0NFF1Adu+7SmEA9606 intact-crc:66EE72D629891156|rigid:uYmi/4i9spIWjsEGUAvsZlc2vvo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14669 uniprotkb:P52294 intact:EBI-308443|uniprotkb:Q15644|ensembl:ENSP00000283943|uniprotkb:D4HL82|uniprotkb:Q14CA3|uniprotkb:Q14CF1|uniprotkb:Q53R87|uniprotkb:Q53TE7 intact:EBI-358383|uniprotkb:Q9BQ56|uniprotkb:Q6IBQ9|intact:EBI-1058734|ensembl:ENSP00000343701|uniprotkb:D3DN93 psi-mi:tripc_human(display_long)|uniprotkb:TRIP12(gene name)|psi-mi:TRIP12(display_short)|uniprotkb:Thyroid receptor-interacting protein 12(gene name synonym)|uniprotkb:KIAA0045(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase for Arf(gene name synonym)|uniprotkb:ULF(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase TRIP12(gene name synonym) psi-mi:ima5_human(display_long)|uniprotkb:KPNA1(gene name)|psi-mi:KPNA1(display_short)|uniprotkb:RCH2(gene name synonym)|uniprotkb:Karyopherin subunit alpha-1(gene name synonym)|uniprotkb:SRP1-beta(gene name synonym)|uniprotkb:RAG cohort protein 2(gene name synonym)|uniprotkb:Nucleoprotein interactor 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836401|imex:IM-21659-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004229.1|refseq:NP_001271143.1|refseq:NP_001271144.1|refseq:NP_001271145.1|ensembl:ENSG00000153827(gene)|ensembl:ENST00000283943(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016607"(nuclear speck)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR000569(HECT)|interpro:IPR004170(WWE)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR035983|interpro:IPR037197|mint:Q14669|reactome:R-HSA-983168|refseq:NP_001335244.1|refseq:NP_001335245.1|ensembl:ENSP00000283943|ensembl:ENST00000389044|ensembl:ENST00000389045|ensembl:ENSP00000373697|ensembl:ENSP00000373696|dip:DIP-58584N|uniprotkb:Q14669(identity)|entrezgene/locuslink:9320(identity)|ddbj/embl/genbank:BC114556(identity) refseq:NP_002255.3|ensembl:ENSG00000114030(gene)|ensembl:ENST00000344337(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014841"(skeletal muscle satellite cell proliferation)|go:"GO:0014901"(satellite cell activation involved in skeletal muscle regeneration)|go:"GO:0030425"(dendrite)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:P52294|rcsb pdb:2JDQ|rcsb pdb:3TJ3|rcsb pdb:4B18|rcsb pdb:6WX9|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-162592|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180910|reactome:R-HSA-909733|reactome:R-HSA-9636249|dip:DIP-29296N|refseq:XP_005247494.1|uniprotkb:P52294(identity)|entrezgene/locuslink:3836(identity) psi-mi:"MI:0469"(intact) caution:This sequence has been withdrawn from Uniprot.|crc64:294A7C063A3332DE - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wzXMKIUEDV4y7YE6PDU+LIPHl7U9606 rogid:eha8sOMYqe0OC6eXBA4eJLLsKFs9606 intact-crc:66EE72D629891156|rigid:uYmi/4i9spIWjsEGUAvsZlc2vvo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14669 uniprotkb:P62891 intact:EBI-308443|uniprotkb:Q15644|ensembl:ENSP00000283943|uniprotkb:D4HL82|uniprotkb:Q14CA3|uniprotkb:Q14CF1|uniprotkb:Q53R87|uniprotkb:Q53TE7 intact:EBI-8830744|uniprotkb:P02404|uniprotkb:Q9BYF2|uniprotkb:P39025|ensembl:ENSP00000355315 psi-mi:tripc_human(display_long)|uniprotkb:TRIP12(gene name)|psi-mi:TRIP12(display_short)|uniprotkb:Thyroid receptor-interacting protein 12(gene name synonym)|uniprotkb:KIAA0045(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase for Arf(gene name synonym)|uniprotkb:ULF(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase TRIP12(gene name synonym) psi-mi:rl39_human(display_long)|uniprotkb:RPL39(gene name)|psi-mi:RPL39(display_short)|uniprotkb:Large ribosomal subunit protein eL39(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836401|imex:IM-21659-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004229.1|refseq:NP_001271143.1|refseq:NP_001271144.1|refseq:NP_001271145.1|ensembl:ENSG00000153827(gene)|ensembl:ENST00000283943(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016607"(nuclear speck)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR000569(HECT)|interpro:IPR004170(WWE)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR035983|interpro:IPR037197|mint:Q14669|reactome:R-HSA-983168|refseq:NP_001335244.1|refseq:NP_001335245.1|ensembl:ENSP00000283943|ensembl:ENST00000389044|ensembl:ENST00000389045|ensembl:ENSP00000373697|ensembl:ENSP00000373696|dip:DIP-58584N|uniprotkb:Q14669(identity)|entrezgene/locuslink:9320(identity)|ddbj/embl/genbank:BC114556(identity) refseq:NP_000991.1|rcsb pdb:4V6X|ensembl:ENSG00000198918(gene)|ensembl:ENST00000361575(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000077(Ribosomal protein L39e)|interpro:IPR020083|interpro:IPR023626|rcsb pdb:4UG0|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|uniprotkb:P62891(identity)|entrezgene/locuslink:6170(identity) psi-mi:"MI:0469"(intact) caution:This sequence has been withdrawn from Uniprot.|crc64:294A7C063A3332DE - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:wzXMKIUEDV4y7YE6PDU+LIPHl7U9606 rogid:AZus2dxwJsTxAOwnJ93E2yhasbo9606 intact-crc:66EE72D629891156|rigid:uYmi/4i9spIWjsEGUAvsZlc2vvo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P25490 uniprotkb:Q9H981 intact:EBI-765538|uniprotkb:Q14935|ensembl:ENSP00000262238 intact:EBI-769597|uniprotkb:Q9H663|uniprotkb:B3KSW7|uniprotkb:Q8N566|ensembl:ENSP00000336842 psi-mi:tyy1_human(display_long)|uniprotkb:Yin and yang 1(gene name synonym)|uniprotkb:Delta transcription factor(gene name synonym)|uniprotkb:NF-E1(gene name synonym)|uniprotkb:YY1(gene name)|psi-mi:YY1(display_short)|uniprotkb:INO80S(gene name synonym)|uniprotkb:INO80 complex subunit S(gene name synonym) psi-mi:arp8_human(display_long)|uniprotkb:ACTR8(gene name)|psi-mi:ACTR8(display_short)|uniprotkb:INO80N(gene name synonym)|uniprotkb:INO80 complex subunit N(gene name synonym)|uniprotkb:ARP8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836427|imex:IM-21659-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003394.1|dip:DIP-150N|ensembl:ENSG00000100811(gene)|rcsb pdb:1UBD|rcsb pdb:1ZNM|rcsb pdb:4C5I|reactome:R-HSA-5617472|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8866910|reactome:R-HSA-9018519|ensembl:ENST00000262238(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006403"(RNA localization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010225"(response to UV-C)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034696"(response to prostaglandin F)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0051276"(chromosome organization)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017114(Transcription factor yin and yang)|interpro:IPR036236|mint:P25490|uniprotkb:P25490(identity)|entrezgene/locuslink:7528(identity)|ddbj/embl/genbank:BC037308(identity) refseq:NP_075050.3|refseq:XP_005265644.1|refseq:XP_011532551.1|ensembl:ENSG00000113812(gene)|ensembl:ENST00000335754(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0031011"(Ino80 complex)|go:"GO:0043044"|go:"GO:0051301"(cell division)|interpro:IPR004000(Actin/actin-like)|interpro:IPR027668|interpro:IPR043129|mint:Q9H981|rcsb pdb:4FO0|reactome:R-HSA-5689603|reactome:R-HSA-5696394|uniprotkb:Q9H981(identity)|entrezgene/locuslink:93973(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/08/05 rogid:OncFlxfcbNZGN68Sk39CRh9oQHc9606 rogid:9bgkh+pDd9OCLZEW1uWg4fXjBIk9606 intact-crc:C63D4EE48E993DC7|rigid:uqFhqlAE057iGdD3bv/1cICSglI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P25490 uniprotkb:Q9Y5K5 intact:EBI-765538|uniprotkb:Q14935|ensembl:ENSP00000262238 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 psi-mi:tyy1_human(display_long)|uniprotkb:Yin and yang 1(gene name synonym)|uniprotkb:Delta transcription factor(gene name synonym)|uniprotkb:NF-E1(gene name synonym)|uniprotkb:YY1(gene name)|psi-mi:YY1(display_short)|uniprotkb:INO80S(gene name synonym)|uniprotkb:INO80 complex subunit S(gene name synonym) psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836427|imex:IM-21659-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003394.1|dip:DIP-150N|ensembl:ENSG00000100811(gene)|rcsb pdb:1UBD|rcsb pdb:1ZNM|rcsb pdb:4C5I|reactome:R-HSA-5617472|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8866910|reactome:R-HSA-9018519|ensembl:ENST00000262238(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006403"(RNA localization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010225"(response to UV-C)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034696"(response to prostaglandin F)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0051276"(chromosome organization)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017114(Transcription factor yin and yang)|interpro:IPR036236|mint:P25490|uniprotkb:P25490(identity)|entrezgene/locuslink:7528(identity)|ddbj/embl/genbank:BC037308(identity) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N|uniprotkb:Q9Y5K5(identity)|entrezgene/locuslink:51377(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/08/05 rogid:OncFlxfcbNZGN68Sk39CRh9oQHc9606 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 intact-crc:C63D4EE48E993DC7|rigid:uqFhqlAE057iGdD3bv/1cICSglI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P25490 uniprotkb:Q6PI98 intact:EBI-765538|uniprotkb:Q14935|ensembl:ENSP00000262238 intact:EBI-722540|uniprotkb:Q86WR1|uniprotkb:Q8N994|uniprotkb:B4DUI4|uniprotkb:E9PCS7|ensembl:ENSP00000334473 psi-mi:tyy1_human(display_long)|uniprotkb:Yin and yang 1(gene name synonym)|uniprotkb:Delta transcription factor(gene name synonym)|uniprotkb:NF-E1(gene name synonym)|uniprotkb:YY1(gene name)|psi-mi:YY1(display_short)|uniprotkb:INO80S(gene name synonym)|uniprotkb:INO80 complex subunit S(gene name synonym) psi-mi:in80c_human(display_long)|uniprotkb:INO80C(gene name)|psi-mi:INO80C(display_short)|uniprotkb:C18orf37(gene name synonym)|uniprotkb:IES6 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836427|imex:IM-21659-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003394.1|dip:DIP-150N|ensembl:ENSG00000100811(gene)|rcsb pdb:1UBD|rcsb pdb:1ZNM|rcsb pdb:4C5I|reactome:R-HSA-5617472|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8866910|reactome:R-HSA-9018519|ensembl:ENST00000262238(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006403"(RNA localization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010225"(response to UV-C)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034696"(response to prostaglandin F)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0051276"(chromosome organization)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017114(Transcription factor yin and yang)|interpro:IPR036236|mint:P25490|uniprotkb:P25490(identity)|entrezgene/locuslink:7528(identity)|ddbj/embl/genbank:BC037308(identity) refseq:NP_919257.2|refseq:NP_001092287.1|ensembl:ENSG00000153391(gene)|ensembl:ENST00000334598(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031011"(Ino80 complex)|go:"GO:0071339"(MLL1 complex)|interpro:IPR013272(YL1 nuclear, C-terminal)|interpro:IPR029525|reactome:R-HSA-5689603|reactome:R-HSA-5696394|uniprotkb:Q6PI98(identity)|entrezgene/locuslink:125476(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/08/05 rogid:OncFlxfcbNZGN68Sk39CRh9oQHc9606 rogid:xo40r8gpMPQv1RCH1FC3De6oKF89606 intact-crc:C63D4EE48E993DC7|rigid:uqFhqlAE057iGdD3bv/1cICSglI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P25490 uniprotkb:Q96EZ8 intact:EBI-765538|uniprotkb:Q14935|ensembl:ENSP00000262238 intact:EBI-348259|ensembl:ENSP00000345358|ensembl:ENSP00000448056|uniprotkb:O14742|uniprotkb:O75497|uniprotkb:Q6VN53|uniprotkb:Q7Z372 psi-mi:tyy1_human(display_long)|uniprotkb:Yin and yang 1(gene name synonym)|uniprotkb:Delta transcription factor(gene name synonym)|uniprotkb:NF-E1(gene name synonym)|uniprotkb:YY1(gene name)|psi-mi:YY1(display_short)|uniprotkb:INO80S(gene name synonym)|uniprotkb:INO80 complex subunit S(gene name synonym) psi-mi:mcrs1_human(display_long)|uniprotkb:MCRS1(gene name)|psi-mi:MCRS1(display_short)|uniprotkb:MSP58(gene name synonym)|uniprotkb:58 kDa microspherule protein(gene name synonym)|uniprotkb:Cell cycle-regulated factor p78(gene name synonym)|uniprotkb:MCRS2(gene name synonym)|uniprotkb:INO80Q(gene name synonym)|uniprotkb:INO80 complex subunit J(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836427|imex:IM-21659-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003394.1|dip:DIP-150N|ensembl:ENSG00000100811(gene)|rcsb pdb:1UBD|rcsb pdb:1ZNM|rcsb pdb:4C5I|reactome:R-HSA-5617472|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8866910|reactome:R-HSA-9018519|ensembl:ENST00000262238(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006403"(RNA localization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010225"(response to UV-C)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034696"(response to prostaglandin F)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0051276"(chromosome organization)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017114(Transcription factor yin and yang)|interpro:IPR036236|mint:P25490|uniprotkb:P25490(identity)|entrezgene/locuslink:7528(identity)|ddbj/embl/genbank:BC037308(identity) ensembl:ENSG00000187778(gene)|ensembl:ENST00000343810(transcript)|ensembl:ENST00000550165(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005844"(polysome)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010521"(telomerase inhibitor activity)|go:"GO:0030425"(dendrite)|go:"GO:0031011"(Ino80 complex)|go:"GO:0034046"("poly(G) binding")|go:"GO:0043204"(perikaryon)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR025999|interpro:IPR037912|mint:Q96EZ8|reactome:R-HSA-3214847|go:"GO:0043984"(histone H4-K16 acetylation)|reactome:R-HSA-5689603|reactome:R-HSA-5696394|refseq:NP_001012300.1|refseq:NP_006328.2|refseq:NP_001265270.1|refseq:XP_005268629.1|refseq:XP_016874178.1|refseq:XP_016874179.1|uniprotkb:Q96EZ8(identity)|entrezgene/locuslink:10445(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/08/05 rogid:OncFlxfcbNZGN68Sk39CRh9oQHc9606 rogid:b6u2XbKLMDkL1zbLTPBjq9J23Zs9606 intact-crc:C63D4EE48E993DC7|rigid:uqFhqlAE057iGdD3bv/1cICSglI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P25490 uniprotkb:O96019 intact:EBI-765538|uniprotkb:Q14935|ensembl:ENSP00000262238 intact:EBI-355018|uniprotkb:Q8TAE5|uniprotkb:Q9BVS8|uniprotkb:Q9H0W6|uniprotkb:B3KMN1|uniprotkb:D3DNR9|ensembl:ENSP00000397552 psi-mi:tyy1_human(display_long)|uniprotkb:Yin and yang 1(gene name synonym)|uniprotkb:Delta transcription factor(gene name synonym)|uniprotkb:NF-E1(gene name synonym)|uniprotkb:YY1(gene name)|psi-mi:YY1(display_short)|uniprotkb:INO80S(gene name synonym)|uniprotkb:INO80 complex subunit S(gene name synonym) psi-mi:acl6a_human(display_long)|uniprotkb:53 kDa BRG1-associated factor A(gene name synonym)|uniprotkb:Actin-related protein Baf53a(gene name synonym)|uniprotkb:ArpNbeta(gene name synonym)|uniprotkb:BAF53A(gene name synonym)|uniprotkb:ACTL6A(gene name)|psi-mi:ACTL6A(display_short)|uniprotkb:BAF53(gene name synonym)|uniprotkb:INO80K(gene name synonym)|uniprotkb:INO80 complex subunit K(gene name synonym)|uniprotkb:BRG1-associated factor 53A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836427|imex:IM-21659-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003394.1|dip:DIP-150N|ensembl:ENSG00000100811(gene)|rcsb pdb:1UBD|rcsb pdb:1ZNM|rcsb pdb:4C5I|reactome:R-HSA-5617472|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8866910|reactome:R-HSA-9018519|ensembl:ENST00000262238(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006403"(RNA localization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010225"(response to UV-C)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034696"(response to prostaglandin F)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0051276"(chromosome organization)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017114(Transcription factor yin and yang)|interpro:IPR036236|mint:P25490|uniprotkb:P25490(identity)|entrezgene/locuslink:7528(identity)|ddbj/embl/genbank:BC037308(identity) refseq:NP_004292.1|refseq:NP_817126.1|refseq:NP_829888.1|ensembl:ENSG00000136518(gene)|ensembl:ENST00000429709(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0003407"(neural retina development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0021510"(spinal cord development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043044"|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0071564"(npBAF complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR043129|mint:O96019|rcsb pdb:6LTJ|reactome:R-HSA-3214847|reactome:R-HSA-3214858|go:"GO:0000785"(chromatin)|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8939243|ensembl:ENST00000392662|ensembl:ENSP00000376430|ensembl:ENSP00000397552|ensembl:ENST00000450518|ensembl:ENSP00000394014|dip:DIP-27565N|uniprotkb:O96019(identity)|entrezgene/locuslink:86(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/08/05 rogid:OncFlxfcbNZGN68Sk39CRh9oQHc9606 rogid:FV8zvQxf2aeHbwFNUpo9JOpj5U49606 intact-crc:C63D4EE48E993DC7|rigid:uqFhqlAE057iGdD3bv/1cICSglI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P25490 uniprotkb:P0C1Z6 intact:EBI-765538|uniprotkb:Q14935|ensembl:ENSP00000262238 intact:EBI-1245626|uniprotkb:G5E9B5|ensembl:ENSP00000375639|ensembl:ENSP00000477775|ensembl:ENSP00000480169|ensembl:ENSP00000480353|ensembl:ENSP00000481443|ensembl:ENSP00000482185|ensembl:ENSP00000482785|ensembl:ENSP00000483417|ensembl:ENSP00000483971|ensembl:ENSP00000484685 psi-mi:tyy1_human(display_long)|uniprotkb:Yin and yang 1(gene name synonym)|uniprotkb:Delta transcription factor(gene name synonym)|uniprotkb:NF-E1(gene name synonym)|uniprotkb:YY1(gene name)|psi-mi:YY1(display_short)|uniprotkb:INO80S(gene name synonym)|uniprotkb:INO80 complex subunit S(gene name synonym) psi-mi:tfpt_human(display_long)|uniprotkb:TFPT(gene name)|psi-mi:TFPT(display_short)|uniprotkb:Protein FB1(gene name synonym)|uniprotkb:INO80F(gene name synonym)|uniprotkb:INO80 complex subunit F(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836427|imex:IM-21659-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003394.1|dip:DIP-150N|ensembl:ENSG00000100811(gene)|rcsb pdb:1UBD|rcsb pdb:1ZNM|rcsb pdb:4C5I|reactome:R-HSA-5617472|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8866910|reactome:R-HSA-9018519|ensembl:ENST00000262238(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006403"(RNA localization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010225"(response to UV-C)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034696"(response to prostaglandin F)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0051276"(chromosome organization)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017114(Transcription factor yin and yang)|interpro:IPR036236|mint:P25490|uniprotkb:P25490(identity)|entrezgene/locuslink:7528(identity)|ddbj/embl/genbank:BC037308(identity) refseq:NP_037474.1|refseq:NP_001308721.1|ensembl:ENSG00000105619(gene)|ensembl:ENSG00000273833(gene)|ensembl:ENSG00000274073(gene)|ensembl:ENSG00000275086(gene)|ensembl:ENSG00000276022(gene)|ensembl:ENSG00000276263(gene)|ensembl:ENSG00000276296(gene)|ensembl:ENSG00000276323(gene)|ensembl:ENSG00000276504(gene)|ensembl:ENSG00000278161(gene)|ensembl:ENST00000391759(transcript)|ensembl:ENST00000611514(transcript)|ensembl:ENST00000611935(transcript)|ensembl:ENST00000614788(transcript)|ensembl:ENST00000615534(transcript)|ensembl:ENST00000615620(transcript)|ensembl:ENST00000616277(transcript)|ensembl:ENST00000616798(transcript)|ensembl:ENST00000617348(transcript)|ensembl:ENST00000619581(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0031011"(Ino80 complex)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|interpro:IPR033555|mint:P0C1Z6|reactome:R-HSA-5689603|reactome:R-HSA-5696394|uniprotkb:P0C1Z6(identity)|entrezgene/locuslink:29844(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/08/05 rogid:OncFlxfcbNZGN68Sk39CRh9oQHc9606 rogid:juI/3gZemjc0hnXDJ9J+bIQ9pBw9606 intact-crc:C63D4EE48E993DC7|rigid:uqFhqlAE057iGdD3bv/1cICSglI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P25490 uniprotkb:Q9H9F9 intact:EBI-765538|uniprotkb:Q14935|ensembl:ENSP00000262238 intact:EBI-769418|uniprotkb:Q86WF7|uniprotkb:Q8IUY5|uniprotkb:Q8N724|uniprotkb:Q9BRN0|uniprotkb:Q9BVB7|ensembl:ENSP00000243903 psi-mi:tyy1_human(display_long)|uniprotkb:Yin and yang 1(gene name synonym)|uniprotkb:Delta transcription factor(gene name synonym)|uniprotkb:NF-E1(gene name synonym)|uniprotkb:YY1(gene name)|psi-mi:YY1(display_short)|uniprotkb:INO80S(gene name synonym)|uniprotkb:INO80 complex subunit S(gene name synonym) psi-mi:arp5_human(display_long)|uniprotkb:Sarcoma antigen NY-SAR-16(gene name synonym)|uniprotkb:ACTR5(gene name)|psi-mi:ACTR5(display_short)|uniprotkb:ARP5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836427|imex:IM-21659-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003394.1|dip:DIP-150N|ensembl:ENSG00000100811(gene)|rcsb pdb:1UBD|rcsb pdb:1ZNM|rcsb pdb:4C5I|reactome:R-HSA-5617472|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8866910|reactome:R-HSA-9018519|ensembl:ENST00000262238(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006403"(RNA localization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010225"(response to UV-C)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034696"(response to prostaglandin F)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0051276"(chromosome organization)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017114(Transcription factor yin and yang)|interpro:IPR036236|mint:P25490|uniprotkb:P25490(identity)|entrezgene/locuslink:7528(identity)|ddbj/embl/genbank:BC037308(identity) refseq:NP_079131.3|dip:DIP-34297N|ensembl:ENSG00000101442(gene)|ensembl:ENST00000243903(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0031011"(Ino80 complex)|go:"GO:0043044"|go:"GO:0070914"(UV-damage excision repair)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR027664|interpro:IPR043129|rcsb pdb:6HTS|reactome:R-HSA-5689603|reactome:R-HSA-5696394|uniprotkb:Q9H9F9(identity)|entrezgene/locuslink:79913(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/08/05 rogid:OncFlxfcbNZGN68Sk39CRh9oQHc9606 rogid:ewlnWvZMDIX84KfZ6XIXXm9NBVI9606 intact-crc:C63D4EE48E993DC7|rigid:uqFhqlAE057iGdD3bv/1cICSglI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P25490 uniprotkb:Q9ULG1 intact:EBI-765538|uniprotkb:Q14935|ensembl:ENSP00000262238 intact:EBI-769345|uniprotkb:Q9NTG6|uniprotkb:A6H8X4|ensembl:ENSP00000384686|ensembl:ENSP00000497609 psi-mi:tyy1_human(display_long)|uniprotkb:Yin and yang 1(gene name synonym)|uniprotkb:Delta transcription factor(gene name synonym)|uniprotkb:NF-E1(gene name synonym)|uniprotkb:YY1(gene name)|psi-mi:YY1(display_short)|uniprotkb:INO80S(gene name synonym)|uniprotkb:INO80 complex subunit S(gene name synonym) psi-mi:ino80_human(display_long)|uniprotkb:INO80A(gene name synonym)|uniprotkb:INO80 complex subunit A(gene name synonym)|uniprotkb:DNA helicase-related INO80 complex homolog 1(gene name synonym)|uniprotkb:INO80(gene name)|psi-mi:INO80(display_short)|uniprotkb:KIAA1259(gene name synonym)|uniprotkb:INOC1(gene name synonym)|uniprotkb:DNA helicase-related protein INO80(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836427|imex:IM-21659-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003394.1|dip:DIP-150N|ensembl:ENSG00000100811(gene)|rcsb pdb:1UBD|rcsb pdb:1ZNM|rcsb pdb:4C5I|reactome:R-HSA-5617472|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8866910|reactome:R-HSA-9018519|ensembl:ENST00000262238(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006403"(RNA localization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010225"(response to UV-C)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034696"(response to prostaglandin F)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0051276"(chromosome organization)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017114(Transcription factor yin and yang)|interpro:IPR036236|mint:P25490|uniprotkb:P25490(identity)|entrezgene/locuslink:7528(identity)|ddbj/embl/genbank:BC037308(identity) refseq:NP_060023.1|dip:DIP-34296N|ensembl:ENSG00000128908(gene)|ensembl:ENST00000401393(transcript)|ensembl:ENST00000648947(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|go:"GO:0016604"(nuclear body)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031011"(Ino80 complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042393"(histone binding)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043044"|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070615"|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|go:"GO:0000724"(double-strand break repair via homologous recombination)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR020838|interpro:IPR027417|interpro:IPR031047|interpro:IPR038718|mint:Q9ULG1|rcsb pdb:6HTS|reactome:R-HSA-5689603|reactome:R-HSA-5696394|uniprotkb:Q9ULG1(identity)|entrezgene/locuslink:54617(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/08/05 rogid:OncFlxfcbNZGN68Sk39CRh9oQHc9606 rogid:HmAPLhnl6NkjlTtWgaOTufUcTgs9606 intact-crc:C63D4EE48E993DC7|rigid:uqFhqlAE057iGdD3bv/1cICSglI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P25490 uniprotkb:Q9Y230 intact:EBI-765538|uniprotkb:Q14935|ensembl:ENSP00000262238 intact:EBI-352939|ensembl:ENSP00000473172|uniprotkb:Q6FIB9|uniprotkb:Q6PK27|uniprotkb:Q9Y361|uniprotkb:B3KQ59|uniprotkb:E7ETE5|intact:EBI-1058527 psi-mi:tyy1_human(display_long)|uniprotkb:Yin and yang 1(gene name synonym)|uniprotkb:Delta transcription factor(gene name synonym)|uniprotkb:NF-E1(gene name synonym)|uniprotkb:YY1(gene name)|psi-mi:YY1(display_short)|uniprotkb:INO80S(gene name synonym)|uniprotkb:INO80 complex subunit S(gene name synonym) psi-mi:ruvb2_human(display_long)|uniprotkb:RUVBL2(gene name)|psi-mi:RUVBL2(display_short)|uniprotkb:TIP48(gene name synonym)|uniprotkb:TIP49B(gene name synonym)|uniprotkb:CGI-46(orf name)|uniprotkb:48 kDa TATA box-binding protein-interacting protein(gene name synonym)|uniprotkb:TIP49b(gene name synonym)|uniprotkb:Repressing pontin 52(gene name synonym)|uniprotkb:51 kDa erythrocyte cytosolic protein(gene name synonym)|uniprotkb:INO80J(gene name synonym)|uniprotkb:TIP60-associated protein 54-beta(gene name synonym)|uniprotkb:INO80 complex subunit J(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836427|imex:IM-21659-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003394.1|dip:DIP-150N|ensembl:ENSG00000100811(gene)|rcsb pdb:1UBD|rcsb pdb:1ZNM|rcsb pdb:4C5I|reactome:R-HSA-5617472|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8866910|reactome:R-HSA-9018519|ensembl:ENST00000262238(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006403"(RNA localization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010225"(response to UV-C)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034696"(response to prostaglandin F)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0051276"(chromosome organization)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017114(Transcription factor yin and yang)|interpro:IPR036236|mint:P25490|uniprotkb:P25490(identity)|entrezgene/locuslink:7528(identity)|ddbj/embl/genbank:BC037308(identity) go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037942|interpro:IPR041048|interpro:IPR042487|mint:Q9Y230|rcsb pdb:2CQA|rcsb pdb:2XSZ|rcsb pdb:3UK6|rcsb pdb:5OAF|rcsb pdb:6FO1|rcsb pdb:6H7X|rcsb pdb:6HTS|rcsb pdb:6IGM|rcsb pdb:6K0R|rcsb pdb:6QI8|rcsb pdb:6QI9|rcsb pdb:7AHO|reactome:R-HSA-171319|go:"GO:0140585"(promoter-enhancer loop anchoring activity)|reactome:R-HSA-3214847|ensembl:ENSG00000183207(gene)|ensembl:ENST00000595090(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000791"(euchromatin)|go:"GO:0000812"(Swr1 complex)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006457"(protein folding)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0016573"(histone acetylation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|refseq:NP_006657.1|refseq:XP_011524632.1|refseq:NP_001308120.1|dip:DIP-28153N|uniprotkb:Q9Y230(identity)|entrezgene/locuslink:10856(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/08/05 rogid:OncFlxfcbNZGN68Sk39CRh9oQHc9606 rogid:APKAWLDCJVULUP3nzqIaSLHKVN49606 intact-crc:C63D4EE48E993DC7|rigid:uqFhqlAE057iGdD3bv/1cICSglI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P25490 uniprotkb:Q9C086 intact:EBI-765538|uniprotkb:Q14935|ensembl:ENSP00000262238 intact:EBI-715611|ensembl:ENSP00000233331 psi-mi:tyy1_human(display_long)|uniprotkb:Yin and yang 1(gene name synonym)|uniprotkb:Delta transcription factor(gene name synonym)|uniprotkb:NF-E1(gene name synonym)|uniprotkb:YY1(gene name)|psi-mi:YY1(display_short)|uniprotkb:INO80S(gene name synonym)|uniprotkb:INO80 complex subunit S(gene name synonym) psi-mi:in80b_human(display_long)|uniprotkb:PAP-1-associated protein 1(gene name synonym)|uniprotkb:High mobility group AT-hook 1-like 4(gene name synonym)|uniprotkb:INO80B(gene name)|psi-mi:INO80B(display_short)|uniprotkb:HMGA1L4(gene name synonym)|uniprotkb:PAPA1(gene name synonym)|uniprotkb:ZNHIT4(gene name synonym)|uniprotkb:Zinc finger HIT domain-containing protein 4(gene name synonym)|uniprotkb:IES2 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836427|imex:IM-21659-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003394.1|dip:DIP-150N|ensembl:ENSG00000100811(gene)|rcsb pdb:1UBD|rcsb pdb:1ZNM|rcsb pdb:4C5I|reactome:R-HSA-5617472|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8866910|reactome:R-HSA-9018519|ensembl:ENST00000262238(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006403"(RNA localization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010225"(response to UV-C)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034696"(response to prostaglandin F)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0051276"(chromosome organization)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017114(Transcription factor yin and yang)|interpro:IPR036236|mint:P25490|uniprotkb:P25490(identity)|entrezgene/locuslink:7528(identity)|ddbj/embl/genbank:BC037308(identity) refseq:NP_112578.2|interpro:IPR029523|mint:Q9C086|rcsb pdb:6HTS|reactome:R-HSA-5689603|reactome:R-HSA-5696394|interpro:IPR007529(Zinc finger, HIT-type)|ensembl:ENSG00000115274(gene)|ensembl:ENST00000233331(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0031011"(Ino80 complex)|go:"GO:0043044"|go:"GO:0046872"(metal ion binding)|interpro:IPR006880(PAPA-1-like conserved region)|uniprotkb:Q9C086(identity)|entrezgene/locuslink:83444(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/08/05 rogid:OncFlxfcbNZGN68Sk39CRh9oQHc9606 rogid:4nwc9Jv4wjrMHJTe7kMJt1Z0nks9606 intact-crc:C63D4EE48E993DC7|rigid:uqFhqlAE057iGdD3bv/1cICSglI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P25490 uniprotkb:Q53TQ3 intact:EBI-765538|uniprotkb:Q14935|ensembl:ENSP00000262238 intact:EBI-769603|uniprotkb:Q6PJU1|uniprotkb:Q6PKA1|uniprotkb:Q9NXD5|uniprotkb:Q6PJC6|uniprotkb:B3KU68|uniprotkb:B9EG77|ensembl:ENSP00000384198|ensembl:ENSP00000490850|intact:EBI-21657516 psi-mi:tyy1_human(display_long)|uniprotkb:Yin and yang 1(gene name synonym)|uniprotkb:Delta transcription factor(gene name synonym)|uniprotkb:NF-E1(gene name synonym)|uniprotkb:YY1(gene name)|psi-mi:YY1(display_short)|uniprotkb:INO80S(gene name synonym)|uniprotkb:INO80 complex subunit S(gene name synonym) psi-mi:in80d_human(display_long)|uniprotkb:INO80D(gene name)|psi-mi:INO80D(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836427|imex:IM-21659-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003394.1|dip:DIP-150N|ensembl:ENSG00000100811(gene)|rcsb pdb:1UBD|rcsb pdb:1ZNM|rcsb pdb:4C5I|reactome:R-HSA-5617472|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8866910|reactome:R-HSA-9018519|ensembl:ENST00000262238(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006403"(RNA localization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010225"(response to UV-C)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034696"(response to prostaglandin F)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0051276"(chromosome organization)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017114(Transcription factor yin and yang)|interpro:IPR036236|mint:P25490|uniprotkb:P25490(identity)|entrezgene/locuslink:7528(identity)|ddbj/embl/genbank:BC037308(identity) refseq:XP_011509677.1|refseq:XP_011509678.1|ensembl:ENSP00000384198|ensembl:ENSP00000490850|ensembl:ENSG00000114933(gene)|ensembl:ENSG00000283510(gene)|ensembl:ENST00000403263(transcript)|ensembl:ENST00000636453(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|interpro:IPR025927|mint:Q53TQ3|reactome:R-HSA-5689603|reactome:R-HSA-5696394|refseq:NP_060229.3|refseq:XP_011509672.1|refseq:XP_011509673.1|refseq:XP_011509675.1|uniprotkb:Q53TQ3(identity)|entrezgene/locuslink:54891(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/08/05 rogid:OncFlxfcbNZGN68Sk39CRh9oQHc9606 rogid:uAVyU39fDAWdiToA8FknicX0g1E9606 intact-crc:C63D4EE48E993DC7|rigid:uqFhqlAE057iGdD3bv/1cICSglI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P25490 uniprotkb:Q9Y265 intact:EBI-765538|uniprotkb:Q14935|ensembl:ENSP00000262238 intact:EBI-353675|uniprotkb:P82276|uniprotkb:Q1KMR0|uniprotkb:Q53HK5|uniprotkb:Q53HL7|uniprotkb:Q53Y27|uniprotkb:Q9BSX9|uniprotkb:B2R5S0|ensembl:ENSP00000318297|ensembl:ENSP00000494621 psi-mi:tyy1_human(display_long)|uniprotkb:Yin and yang 1(gene name synonym)|uniprotkb:Delta transcription factor(gene name synonym)|uniprotkb:NF-E1(gene name synonym)|uniprotkb:YY1(gene name)|psi-mi:YY1(display_short)|uniprotkb:INO80S(gene name synonym)|uniprotkb:INO80 complex subunit S(gene name synonym) psi-mi:ruvb1_human(display_long)|uniprotkb:RUVBL1(gene name)|psi-mi:RUVBL1(display_short)|uniprotkb:NMP238(gene name synonym)|uniprotkb:TIP49(gene name synonym)|uniprotkb:TIP49A(gene name synonym)|uniprotkb:49 kDa TATA box-binding protein-interacting protein(gene name synonym)|uniprotkb:TIP49a(gene name synonym)|uniprotkb:Pontin 52(gene name synonym)|uniprotkb:Nuclear matrix protein 238(gene name synonym)|uniprotkb:54 kDa erythrocyte cytosolic protein(gene name synonym)|uniprotkb:INO80H(gene name synonym)|uniprotkb:TIP60-associated protein 54-alpha(gene name synonym)|uniprotkb:INO80 complex subunit H(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836427|imex:IM-21659-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003394.1|dip:DIP-150N|ensembl:ENSG00000100811(gene)|rcsb pdb:1UBD|rcsb pdb:1ZNM|rcsb pdb:4C5I|reactome:R-HSA-5617472|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8866910|reactome:R-HSA-9018519|ensembl:ENST00000262238(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006403"(RNA localization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010225"(response to UV-C)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034696"(response to prostaglandin F)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0051276"(chromosome organization)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017114(Transcription factor yin and yang)|interpro:IPR036236|mint:P25490|uniprotkb:P25490(identity)|entrezgene/locuslink:7528(identity)|ddbj/embl/genbank:BC037308(identity) refseq:NP_003698.1|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016573"(histone acetylation)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037938|interpro:IPR041048|mint:Q9Y265|rcsb pdb:2C9O|rcsb pdb:2XSZ|rcsb pdb:5OAF|rcsb pdb:6FO1|rcsb pdb:6HTS|rcsb pdb:6IGM|rcsb pdb:6K0R|rcsb pdb:6QI8|rcsb pdb:6QI9|rcsb pdb:7AHO|reactome:R-HSA-171319|reactome:R-HSA-201722|reactome:R-HSA-3214847|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5696394|reactome:R-HSA-606279|ensembl:ENSG00000175792(gene)|ensembl:ENSG00000284901(gene)|ensembl:ENST00000322623(transcript)|ensembl:ENST00000643444(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|refseq:NP_001306013.1|dip:DIP-29937N|uniprotkb:Q9Y265(identity)|entrezgene/locuslink:8607(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/08/05 rogid:OncFlxfcbNZGN68Sk39CRh9oQHc9606 rogid:+FA/xQTUldQoWGRgad9U8vZpTHw9606 intact-crc:C63D4EE48E993DC7|rigid:uqFhqlAE057iGdD3bv/1cICSglI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P25490 uniprotkb:Q6P4R8 intact:EBI-765538|uniprotkb:Q14935|ensembl:ENSP00000262238 intact:EBI-2511210|ensembl:ENSP00000400476|ensembl:ENSP00000433572|ensembl:ENSP00000506850|uniprotkb:Q12869|uniprotkb:Q9H048|uniprotkb:Q15312 psi-mi:tyy1_human(display_long)|uniprotkb:Yin and yang 1(gene name synonym)|uniprotkb:Delta transcription factor(gene name synonym)|uniprotkb:NF-E1(gene name synonym)|uniprotkb:YY1(gene name)|psi-mi:YY1(display_short)|uniprotkb:INO80S(gene name synonym)|uniprotkb:INO80 complex subunit S(gene name synonym) psi-mi:nfrkb_human(display_long)|uniprotkb:NFRKB(gene name)|psi-mi:NFRKB(display_short)|uniprotkb:INO80G(gene name synonym)|uniprotkb:DNA-binding protein R kappa-B(gene name synonym)|uniprotkb:INO80 complex subunit G(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836427|imex:IM-21659-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003394.1|dip:DIP-150N|ensembl:ENSG00000100811(gene)|rcsb pdb:1UBD|rcsb pdb:1ZNM|rcsb pdb:4C5I|reactome:R-HSA-5617472|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8866910|reactome:R-HSA-9018519|ensembl:ENST00000262238(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006403"(RNA localization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010225"(response to UV-C)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034696"(response to prostaglandin F)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0051276"(chromosome organization)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017114(Transcription factor yin and yang)|interpro:IPR036236|mint:P25490|uniprotkb:P25490(identity)|entrezgene/locuslink:7528(identity)|ddbj/embl/genbank:BC037308(identity) ensembl:ENSG00000170322(gene)|ensembl:ENST00000446488(transcript)|ensembl:ENST00000524746(transcript)|ensembl:ENST00000682444(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0031011"(Ino80 complex)|interpro:IPR024867|interpro:IPR025220|interpro:IPR038106|interpro:IPR044867|mint:Q6P4R8|rcsb pdb:3U21|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-5689603|reactome:R-HSA-5696394|refseq:XP_011541153.1|refseq:XP_011541154.1|refseq:NP_001137307.1|refseq:NP_006156.2|refseq:XP_016873285.1|uniprotkb:Q6P4R8(identity)|entrezgene/locuslink:4798(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/08/05 rogid:OncFlxfcbNZGN68Sk39CRh9oQHc9606 rogid:3eKREgXAhhBBuj4ZcG0tm4Iar3g9606 intact-crc:C63D4EE48E993DC7|rigid:uqFhqlAE057iGdD3bv/1cICSglI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P25490 uniprotkb:Q8NBZ0 intact:EBI-765538|uniprotkb:Q14935|ensembl:ENSP00000262238 intact:EBI-769401|uniprotkb:Q6Y2K3|intact:EBI-28973946|ensembl:ENSP00000457016 psi-mi:tyy1_human(display_long)|uniprotkb:Yin and yang 1(gene name synonym)|uniprotkb:Delta transcription factor(gene name synonym)|uniprotkb:NF-E1(gene name synonym)|uniprotkb:YY1(gene name)|psi-mi:YY1(display_short)|uniprotkb:INO80S(gene name synonym)|uniprotkb:INO80 complex subunit S(gene name synonym) psi-mi:in80e_human(display_long)|uniprotkb:CCDC95(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 95(gene name synonym)|uniprotkb:INO80E(gene name)|psi-mi:INO80E(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836427|imex:IM-21659-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003394.1|dip:DIP-150N|ensembl:ENSG00000100811(gene)|rcsb pdb:1UBD|rcsb pdb:1ZNM|rcsb pdb:4C5I|reactome:R-HSA-5617472|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8866910|reactome:R-HSA-9018519|ensembl:ENST00000262238(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006403"(RNA localization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010225"(response to UV-C)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034696"(response to prostaglandin F)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0051276"(chromosome organization)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017114(Transcription factor yin and yang)|interpro:IPR036236|mint:P25490|uniprotkb:P25490(identity)|entrezgene/locuslink:7528(identity)|ddbj/embl/genbank:BC037308(identity) refseq:NP_775889.1|ensembl:ENST00000562441|ensembl:ENSP00000456073|ensembl:ENSP00000457016|ensembl:ENST00000567065|ensembl:ENSP00000454665|ensembl:ENST00000620599|ensembl:ENSP00000484187|refseq:NP_001291491.1|refseq:NP_001291492.1|ensembl:ENSG00000169592(gene)|ensembl:ENST00000563197(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031011"(Ino80 complex)|interpro:IPR026678|mint:Q8NBZ0|reactome:R-HSA-5689603|reactome:R-HSA-5696394|uniprotkb:Q8NBZ0(identity)|entrezgene/locuslink:283899(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/08/05 rogid:OncFlxfcbNZGN68Sk39CRh9oQHc9606 rogid:gGBXpYQkxY5mcF4I/4rTzjXZbG09606 intact-crc:C63D4EE48E993DC7|rigid:uqFhqlAE057iGdD3bv/1cICSglI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q2QGD7 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-1538838|uniprotkb:Q7L3L1|uniprotkb:Q8NAU2|uniprotkb:C5J0H9|uniprotkb:Q6DKI8|ensembl:ENSP00000374359|intact:EBI-28981670 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:zxdc_human(display_long)|uniprotkb:ZXDC(gene name)|psi-mi:ZXDC(display_short)|uniprotkb:ZXDL(gene name synonym)|uniprotkb:ZXD-like zinc finger protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_001035743.1|refseq:NP_079388.3|ensembl:ENST00000336332|ensembl:ENSP00000337694|ensembl:ENSP00000374359|ensembl:ENSG00000070476(gene)|ensembl:ENST00000389709(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030275"(LRR domain binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070742"(C2H2 zinc finger domain binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q2QGD7|uniprotkb:Q2QGD7(identity)|entrezgene/locuslink:79364(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:2oqRV2O8vmW9f6FeX+td6cvhyNI9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q6PEV8 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-4280426|uniprotkb:Q8WVP6|uniprotkb:Q96AV3|ensembl:ENSP00000417581 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:f199x_human(display_long)|uniprotkb:FAM199X(gene name)|psi-mi:FAM199X(display_short)|uniprotkb:CXorf39(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_997201.1|refseq:XP_005262136.1|ensembl:ENSG00000123575(gene)|ensembl:ENST00000493442(transcript)|interpro:IPR029672|mint:Q6PEV8|uniprotkb:Q6PEV8(identity)|entrezgene/locuslink:139231(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:yy2plvcV+J7AM2flWIBz8+uEzZ09606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:P51610 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-396176|intact:EBI-2832627|uniprotkb:Q6P4G5|intact:EBI-12037257|intact:EBI-14324845|ensembl:ENSP00000309555|intact:EBI-12980473 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:hcfc1_human(display_long)|uniprotkb:HCFC1(gene name)|psi-mi:HCFC1(display_short)|uniprotkb:HCF1(gene name synonym)|uniprotkb:C1 factor(gene name synonym)|uniprotkb:VP16 accessory protein(gene name synonym)|uniprotkb:VCAF(gene name synonym)|uniprotkb:CFF(gene name synonym)|uniprotkb:HFC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_005325.2|refseq:XP_006724879.1|rcsb pdb:6MA1|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|reactome:R-HSA-2151201|reactome:R-HSA-3214847|reactome:R-HSA-5689603|ensembl:ENSG00000172534(gene)|ensembl:ENST00000310441(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019046"(release from viral latency)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR036116|interpro:IPR037854|interpro:IPR043536|mint:P51610|rcsb pdb:4GO6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:5LWV|dip:DIP-32955N|uniprotkb:P51610(identity)|entrezgene/locuslink:3054(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:RzsCRe9l6md3DI87H4ZgdR9oBMI9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q9H9L4 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-2560840|uniprotkb:Q8N3B5|uniprotkb:Q9NX51|uniprotkb:Q96CV0|ensembl:ENSP00000415436 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:kanl2_human(display_long)|uniprotkb:KANSL2(gene name)|psi-mi:KANSL2(display_short)|uniprotkb:C12orf41(gene name synonym)|uniprotkb:NSL complex protein NSL2(gene name synonym)|uniprotkb:NSL2(gene name synonym)|uniprotkb:Non-specific lethal 2 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_060292.3|ensembl:ENSG00000139620(gene)|ensembl:ENST00000420613(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044545"(NSL complex)|interpro:IPR025927|interpro:IPR026316|mint:Q9H9L4|rcsb pdb:4CY2|reactome:R-HSA-3214847|uniprotkb:Q9H9L4(identity)|entrezgene/locuslink:54934(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:ymOXqnaeH6HuGcHPg4R2XVmWAz89606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q92769 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-301821|uniprotkb:Q5SRI8|uniprotkb:Q5SZ86|uniprotkb:Q8NEH4|uniprotkb:B4DL58|ensembl:ENSP00000430432|uniprotkb:E1P561|uniprotkb:B3KRS5 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:hdac2_human(display_long)|uniprotkb:HDAC2(gene name)|psi-mi:HDAC2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035094"(response to nicotine)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042220"(response to cocaine)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q92769|rcsb pdb:3MAX|rcsb pdb:4LXZ|rcsb pdb:4LY1|rcsb pdb:5IWG|rcsb pdb:5IX0|rcsb pdb:6G3O|rcsb pdb:6WBW|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000196591(gene)|ensembl:ENST00000519065(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|rcsb pdb:6WHN|rcsb pdb:6WHO|rcsb pdb:6WHQ|rcsb pdb:6WHZ|rcsb pdb:6WI3|rcsb pdb:6XDM|rcsb pdb:6XEB|rcsb pdb:6XEC|rcsb pdb:7KBG|rcsb pdb:7KBH|rcsb pdb:7LTG|rcsb pdb:7LTK|rcsb pdb:7LTL|reactome:R-HSA-193670|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9615017|reactome:R-HSA-9619665|reactome:R-HSA-9679191|reactome:R-HSA-983231|rcsb pdb:6WBZ|refseq:NP_001518.3|dip:DIP-24220N|refseq:XP_011534090.1|refseq:XP_016866288.1|uniprotkb:Q92769(identity)|entrezgene/locuslink:3066(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:K4PpGz9E9/TrQZsgvrJuc+uYCn89606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q15291 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-592823|uniprotkb:A8K272|uniprotkb:Q7Z6D8|uniprotkb:Q8NDZ7|ensembl:ENSP00000264515 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:rbbp5_human(display_long)|uniprotkb:Retinoblastoma-binding protein RBQ-3(gene name synonym)|uniprotkb:RBBP5(gene name)|psi-mi:RBBP5(display_short)|uniprotkb:RBQ3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_001180201.1|refseq:NP_001180202.1|refseq:NP_005048.2|dip:DIP-29224N|ensembl:ENSG00000117222(gene)|ensembl:ENST00000264515(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037850|mint:Q15291|rcsb pdb:3P4F|rcsb pdb:4X8N|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6KM7|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6PWX|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|uniprotkb:Q15291(identity)|entrezgene/locuslink:5929(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:Zl8yHcbL1C6StHPyD+875Ccy6gk9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q9H8E8 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-750907|uniprotkb:Q96GW6|uniprotkb:Q96IH3|uniprotkb:Q9HBF0|uniprotkb:Q9UIY5|uniprotkb:A2A2I5|ensembl:ENSP00000366909|ensembl:ENSP00000392318|ensembl:ENSP00000424752|ensembl:ENSP00000503109|ensembl:ENSP00000503493|ensembl:ENSP00000504050|ensembl:ENSP00000504276 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:csr2b_human(display_long)|uniprotkb:KAT14(gene name)|psi-mi:KAT14(display_short)|uniprotkb:ADA2A-containing complex subunit 2(gene name synonym)|uniprotkb:CRP2-binding partner(gene name synonym)|uniprotkb:CSRP2BP(gene name synonym)|uniprotkb:Lysine acetyltransferase 14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_065397.3|ensembl:ENSG00000149474(gene)|ensembl:ENST00000377681(transcript)|ensembl:ENST00000435364(transcript)|ensembl:ENST00000464792(transcript)|ensembl:ENST00000676935(transcript)|ensembl:ENST00000677174(transcript)|ensembl:ENST00000677266(transcript)|ensembl:ENST00000678772(transcript)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0030274"(LIM domain binding)|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR037829|mint:Q9H8E8|reactome:R-HSA-3214847|uniprotkb:Q9H8E8(identity)|entrezgene/locuslink:57325(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:/Udl5yqzzDQ9jsscSVJlzcGd/VI9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:O75528 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-473249|uniprotkb:Q9UFS2|intact:EBI-28973289|ensembl:ENSP00000307684|ensembl:ENSP00000393471|uniprotkb:Q6FI83 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:tada3_human(display_long)|uniprotkb:ADA3 homolog(gene name synonym)|uniprotkb:STAF54(gene name synonym)|uniprotkb:TADA3(gene name)|psi-mi:TADA3(display_short)|uniprotkb:ADA3(gene name synonym)|uniprotkb:TADA3L(gene name synonym)|uniprotkb:Transcriptional adapter 3-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) ensembl:ENSG00000171148(gene)|ensembl:ENST00000301964(transcript)|ensembl:ENST00000440161(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030914"|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR019340|mint:O75528|reactome:R-HSA-3214847|reactome:R-HSA-5689880|ensembl:ENSP00000307684|ensembl:ENST00000343450|ensembl:ENSP00000343649|ensembl:ENSP00000393471|refseq:NP_006345.1|refseq:NP_597814.1|refseq:NP_001265199.1|uniprotkb:O75528(identity)|entrezgene/locuslink:10474(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:5NQkQiw+G/8uL2fjoMgW8+mTB8o9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:O00255 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-592789|uniprotkb:O00632|uniprotkb:Q9BUK2|uniprotkb:A5HBC6|uniprotkb:A5HBC7|uniprotkb:A5HBC8|uniprotkb:A5HBC9|uniprotkb:A5HBD0|uniprotkb:A5HBD1|uniprotkb:A5HBD2|uniprotkb:Q9BUF0|ensembl:ENSP00000366530 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:men1_human(display_long)|uniprotkb:MEN1(gene name)|psi-mi:MEN1(display_short)|uniprotkb:SCG2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_000235.2|refseq:NP_570711.1|refseq:NP_570712.1|refseq:NP_570713.1|refseq:NP_570714.1|refseq:NP_570715.1|refseq:NP_570716.1|refseq:XP_005274058.1|refseq:XP_016873258.1|refseq:XP_016873259.1|dip:DIP-24236N|ensembl:ENSG00000133895(gene)|ensembl:ENST00000377313(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002076"(osteoblast development)|go:"GO:0003309"(type B pancreatic cell differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032925"(regulation of activin receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046697"(decidualization)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0061469"(regulation of type B pancreatic cell proliferation)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071559"(response to transforming growth factor beta)|go:"GO:1902807"(negative regulation of cell cycle G1/S phase transition)|interpro:IPR007747(Menin)|mint:O00255|rcsb pdb:3U84|rcsb pdb:3U85|rcsb pdb:3U86|rcsb pdb:3U88|rcsb pdb:4GPQ|rcsb pdb:4GQ3|rcsb pdb:4GQ4|rcsb pdb:4GQ6|rcsb pdb:4I80|rcsb pdb:4OG3|rcsb pdb:4OG4|rcsb pdb:4OG5|rcsb pdb:4OG6|rcsb pdb:4OG7|rcsb pdb:4OG8|rcsb pdb:4X5Y|rcsb pdb:4X5Z|rcsb pdb:5DB0|rcsb pdb:5DB1|rcsb pdb:5DB2|rcsb pdb:5DB3|rcsb pdb:5DD9|rcsb pdb:5DDA|rcsb pdb:5DDB|rcsb pdb:5DDC|rcsb pdb:5DDD|rcsb pdb:5DDF|rcsb pdb:6B41|rcsb pdb:6BXH|rcsb pdb:6BXY|rcsb pdb:6BY8|rcsb pdb:6E1A|rcsb pdb:6O5I|rcsb pdb:6OPJ|rcsb pdb:6PKC|rcsb pdb:6WNH|reactome:R-HSA-201722|reactome:R-HSA-2173796|reactome:R-HSA-3769402|reactome:R-HSA-381426|reactome:R-HSA-5626467|reactome:R-HSA-8957275|rcsb pdb:5DDE|uniprotkb:O00255(identity)|entrezgene/locuslink:4221(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:gXAt4cxheS3wgMbFtc8ACfkHRH09606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:P61244 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750|uniprotkb:P61244(identity)|entrezgene/locuslink:4149(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:I5d1d/zT353OsLios95yEITNoWU9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q9P2R6 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-948076|uniprotkb:O43393|uniprotkb:O75046|uniprotkb:O75359|uniprotkb:Q5VXL9|uniprotkb:Q6P6B9|uniprotkb:Q9Y2W4|ensembl:ENSP00000338629|ensembl:ENSP00000383700 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:rere_human(display_long)|uniprotkb:Atrophin-1-related protein(gene name synonym)|uniprotkb:Atrophin-1-like protein(gene name synonym)|uniprotkb:RERE(gene name)|psi-mi:RERE(display_short)|uniprotkb:ARG(gene name synonym)|uniprotkb:ARP(gene name synonym)|uniprotkb:ATN1L(gene name synonym)|uniprotkb:KIAA0458(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_001036146.1|refseq:NP_001036147.1|refseq:NP_036234.3|refseq:XP_005263521.1|refseq:XP_016856847.1|refseq:XP_016856848.1|dip:DIP-47606N|ensembl:ENSG00000142599(gene)|ensembl:ENST00000337907(transcript)|ensembl:ENST00000400908(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0021691"(cerebellar Purkinje cell layer maturation)|go:"GO:0021930"(cerebellar granule cell precursor proliferation)|go:"GO:0021942"(radial glia guided migration of Purkinje cell)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0048755"(branching morphogenesis of a nerve)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR002951(Atrophin)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|mint:Q9P2R6|rcsb pdb:2YQK|uniprotkb:Q9P2R6(identity)|entrezgene/locuslink:473(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:fryo3nxpHdcexG2dqy00t0n4Nlw9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q9UBL3 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|ensembl:ENSP00000340896|uniprotkb:A8K7C3|uniprotkb:D3DSW9 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_001098684.1|refseq:NP_004665.2|ensembl:ENSG00000129691(gene)|ensembl:ENST00000343823(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|rcsb pdb:4X8N|refseq:NP_001248761.1|dip:DIP-29222N|uniprotkb:Q9UBL3(identity)|entrezgene/locuslink:9070(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q6ZW49 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-743225|ensembl:ENSP00000380376|ensembl:ENSP00000384048|uniprotkb:O15404|uniprotkb:Q6N099|uniprotkb:Q6ZWH9|uniprotkb:Q7Z315|uniprotkb:Q86UN0|uniprotkb:Q8N4P9|uniprotkb:Q96HP2 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:paxi1_human(display_long)|uniprotkb:PAX transactivation activation domain-interacting protein(gene name synonym)|uniprotkb:PAXIP1(gene name)|psi-mi:PAXIP1(display_short)|uniprotkb:PAXIP1L(gene name synonym)|uniprotkb:PTIP(gene name synonym)|uniprotkb:CAGF28(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) go:"GO:0006310"(DNA recombination)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060717"(chorion development)|go:"GO:1902749"(regulation of cell cycle G2/M phase transition)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR001357(BRCT)|interpro:IPR036420|interpro:IPR037886|mint:Q6ZW49|rcsb pdb:3SQD|reactome:R-HSA-5617472|reactome:R-HSA-5693571|refseq:NP_031375.3|ensembl:ENSG00000157212(gene)|ensembl:ENST00000397192(transcript)|ensembl:ENST00000404141(transcript)|go:"GO:0000416"(positive regulation of histone H3-K36 methylation)|go:"GO:0001570"(vasculogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006281"(DNA repair)|refseq:XP_005249596.1|refseq:XP_016867370.1|dip:DIP-41786N|uniprotkb:Q6ZW49(identity)|entrezgene/locuslink:22976(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:djzoPtMxXMP9LBvpzVNBcq04QEY9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q9BTK6 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-2372223|uniprotkb:A2ICR6|ensembl:ENSP00000326519 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:pagr1_human(display_long)|uniprotkb:PAGR1(gene name)|psi-mi:PAGR1(display_short)|uniprotkb:C16orf53(gene name synonym)|uniprotkb:PA1(gene name synonym)|uniprotkb:PAXIP1-associated protein 1(gene name synonym)|uniprotkb:PTIP-associated protein 1(gene name synonym)|uniprotkb:Glutamate-rich coactivator interacting with SRC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_078792.1|ensembl:ENSG00000280789(gene)|ensembl:ENST00000320330(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR028213|mint:Q9BTK6|reactome:R-HSA-5617472|uniprotkb:Q9BTK6(identity)|entrezgene/locuslink:79447(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:9yYPNooDxUEqCQX/n3OUxtRnM9U9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:O15550 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-4292203|uniprotkb:Q52LL9|uniprotkb:Q5JVQ7|intact:EBI-28988602|ensembl:ENSP00000367203 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:kdm6a_human(display_long)|uniprotkb:KDM6A(gene name)|psi-mi:KDM6A(display_short)|uniprotkb:UTX(gene name synonym)|uniprotkb:Histone demethylase UTX(gene name synonym)|uniprotkb:Ubiquitously-transcribed TPR protein on the X chromosome(gene name synonym)|uniprotkb:Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(27) demethylase 6A"(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_066963.2|ensembl:ENSG00000147050(gene)|ensembl:ENST00000377967(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007507"(heart development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071557"(histone H3-K27 demethylation)|go:"GO:0071558"(histone H3-tri/di-methyl-lysine-27 demethylase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O15550|rcsb pdb:3AVR|rcsb pdb:3AVS|rcsb pdb:6FUK|rcsb pdb:6FUL|reactome:R-HSA-3214842|reactome:R-HSA-5617472|ensembl:ENSP00000367203|dip:DIP-46192N|uniprotkb:O15550(identity)|entrezgene/locuslink:7403(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:sqg+Ikkgvz0uT/gMx1wYs9FaDbI9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q6ZSY5 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-6380932|intact:EBI-28972170|ensembl:ENSP00000055335|uniprotkb:B3KPW2|uniprotkb:A2VDJ8|uniprotkb:E9PCM3 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:ppr3f_human(display_long)|uniprotkb:PPP1R3F(gene name)|psi-mi:PPP1R3F(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) ensembl:ENSP00000055335|ensembl:ENST00000376188|ensembl:ENSP00000365359|ensembl:ENST00000466508|ensembl:ENSP00000420687|ensembl:ENST00000495799|ensembl:ENSP00000417535|ensembl:ENSG00000049769(gene)|ensembl:ENST00000055335(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:2000465"("regulation of glycogen (starch) synthase activity")|go:"GO:2001069"(glycogen binding)|interpro:IPR005036(Putative phosphatase regulatory subunit)|mint:Q6ZSY5|refseq:NP_149992.3|refseq:NP_001171674.1|uniprotkb:Q6ZSY5(identity)|entrezgene/locuslink:89801(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:5V2jQmEgl/UKhLyVIbNGwm8VwCw9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q9P209 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-739498|uniprotkb:Q9BV03|uniprotkb:Q9BWM3|uniprotkb:Q9NVR4|uniprotkb:B4DR26|ensembl:ENSP00000264935 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:cep72_human(display_long)|uniprotkb:CEP72(gene name)|psi-mi:CEP72(display_short)|uniprotkb:KIAA1519(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_060610.2|ensembl:ENSG00000112877(gene)|ensembl:ENST00000264935(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007051"(spindle organization)|go:"GO:0007099"(centriole replication)|go:"GO:0033566"(gamma-tubulin complex localization)|go:"GO:0034451"(centriolar satellite)|go:"GO:1904779"(regulation of protein localization to centrosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR032675|interpro:IPR040146|mint:Q9P209|reactome:R-HSA-2565942|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|refseq:XP_011512365.1|dip:DIP-54272N|uniprotkb:Q9P209(identity)|entrezgene/locuslink:55722(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:c00WdgE2iudiQUz3kXNZL5d0nuQ9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q9ULM3 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-2795509|uniprotkb:A7E2B9|uniprotkb:Q641P6|uniprotkb:Q9NW96|uniprotkb:D3DNS9|ensembl:ENSP00000306983 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:yets2_human(display_long)|uniprotkb:YEATS2(gene name)|psi-mi:YEATS2(display_short)|uniprotkb:KIAA1197(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_060493.3|refseq:XP_016862298.1|refseq:XP_016862299.1|reactome:R-HSA-3214847|rcsb pdb:6LSD|ensembl:ENST00000305135(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0072686"(mitotic spindle)|go:"GO:0140030"(modification-dependent protein binding)|interpro:IPR005033(YEATS)|interpro:IPR038704|mint:Q9ULM3|rcsb pdb:5IQL|ensembl:ENSG00000163872(gene)|rcsb pdb:5XNV|uniprotkb:Q9ULM3(identity)|entrezgene/locuslink:55689(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:dbdCDssB6o5aHKaRdnvITi8b/v09606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:P48643 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N|uniprotkb:P48643(identity)|entrezgene/locuslink:22948(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q8NEZ4 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-1042997|uniprotkb:Q8NC02|uniprotkb:Q8NDF6|uniprotkb:Q9H9P4|uniprotkb:Q9NR13|uniprotkb:Q9P222|uniprotkb:Q9UDR7|ensembl:ENSP00000262189 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:kmt2c_human(display_long)|uniprotkb:KMT2C(gene name)|psi-mi:KMT2C(display_short)|uniprotkb:HALR(gene name synonym)|uniprotkb:Homologous to ALR protein(gene name synonym)|uniprotkb:KIAA1506(gene name synonym)|uniprotkb:MLL3(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) ensembl:ENSG00000055609(gene)|ensembl:ENST00000262189(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR000637(HMG-I and HMG-Y, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|go:"GO:0005634"(nucleus)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036910|interpro:IPR037877|interpro:IPR041967|interpro:IPR041968|mint:Q8NEZ4|rcsb pdb:2YSM|rcsb pdb:2YUK|rcsb pdb:3UVL|rcsb pdb:4ERY|rcsb pdb:5F59|rcsb pdb:5F6K|rcsb pdb:6KIW|rcsb pdb:6MLC|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8936459|refseq:NP_733751.2|ensembl:ENSP00000262189|ensembl:ENST00000682283|ensembl:ENSP00000507485|dip:DIP-48649N|uniprotkb:Q8NEZ4(identity)|entrezgene/locuslink:58508(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:NZg8HgfbohMT8EEgAdAgWR1AjSo9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:O15294 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N|uniprotkb:O15294(identity)|entrezgene/locuslink:8473(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q68DK7 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-2560816|ensembl:ENSP00000381543|uniprotkb:Q69Z03|uniprotkb:Q0VF46|intact:EBI-2654071 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:msl1_human(display_long)|uniprotkb:MSL1(gene name)|psi-mi:MSL1(display_short)|uniprotkb:MSL1L1(gene name synonym)|uniprotkb:Male-specific lethal 1-like 1(gene name synonym)|uniprotkb:Male-specific lethal-1 homolog 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) ensembl:ENSG00000188895(gene)|ensembl:ENST00000398532(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0072487"(MSL complex)|interpro:IPR026711|interpro:IPR029332|interpro:IPR031840|mint:Q68DK7|rcsb pdb:4B7Y|rcsb pdb:4B86|rcsb pdb:4DNC|reactome:R-HSA-3214847|refseq:NP_001012241.1|refseq:XP_005257355.1|dip:DIP-56862N|uniprotkb:Q68DK7(identity)|entrezgene/locuslink:339287(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:sFenPEZNoGtpn1bDFoUzSJBPUBY9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q99496 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|entrezgene/locuslink:6045(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q9BPZ7 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-749938|uniprotkb:Q00426|intact:EBI-1237531|uniprotkb:A8K1Z5|uniprotkb:B1AMA4|uniprotkb:Q5JSV5|uniprotkb:Q5JSV6|uniprotkb:Q5JSV9|uniprotkb:Q658R0|uniprotkb:Q699U1|uniprotkb:Q699U2|uniprotkb:Q699U3|uniprotkb:Q699U4|uniprotkb:Q6GVJ0|uniprotkb:Q6GVJ1|uniprotkb:Q6GVJ2|intact:EBI-1048293|uniprotkb:B7Z309|ensembl:ENSP00000265960|ensembl:ENSP00000362597 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:sin1_human(display_long)|uniprotkb:MIP1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 2-associated protein 1(gene name synonym)|uniprotkb:Stress-activated map kinase-interacting protein 1(gene name synonym)|uniprotkb:MAPKAP1(gene name)|psi-mi:MAPKAP1(display_short)|uniprotkb:SIN1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_001006618.1|refseq:NP_001006619.1|refseq:NP_001006620.1|refseq:NP_001006621.1|refseq:NP_001006622.1|refseq:NP_077022.1|refseq:XP_011517312.1|refseq:XP_016870615.1|dip:DIP-39480N|ensembl:ENSG00000119487(gene)|ensembl:ENST00000265960(transcript)|ensembl:ENST00000373498(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031932"(TORC2 complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|interpro:IPR008828(Stress-activated map kinase interacting 1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031313|interpro:IPR031567|interpro:IPR032679|mint:Q9BPZ7|rcsb pdb:3VOQ|rcsb pdb:5ZCS|rcsb pdb:6ZWM|rcsb pdb:6ZWO|reactome:R-HSA-1257604|reactome:R-HSA-389357|reactome:R-HSA-5218920|reactome:R-HSA-5674400|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|reactome:R-HSA-6804757|refseq:XP_016870616.1|uniprotkb:Q9BPZ7(identity)|entrezgene/locuslink:79109(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:kIAa8HfqaJhvssnCDV2/8fj3JYA9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q13185 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q9BVI0 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-2560802|intact:EBI-3962525|uniprotkb:Q566Q2|uniprotkb:Q66K49|uniprotkb:A7E235|uniprotkb:Q9H4J6|uniprotkb:Q9BXA3|uniprotkb:B2RB56|uniprotkb:Q9BZW3|uniprotkb:Q9NZ22|uniprotkb:Q9BWV4|uniprotkb:Q9H421|uniprotkb:Q5JWY9|uniprotkb:E1P5S3|ensembl:ENSP00000363124 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:phf20_human(display_long)|uniprotkb:Transcription factor TZP(gene name synonym)|uniprotkb:Novel zinc finger protein(gene name synonym)|uniprotkb:PHF20(gene name)|psi-mi:PHF20(display_short)|uniprotkb:C20orf104(gene name synonym)|uniprotkb:GLEA2(gene name synonym)|uniprotkb:HCA58(gene name synonym)|uniprotkb:NZF(gene name synonym)|uniprotkb:TZP(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 58(gene name synonym)|uniprotkb:Glioma-expressed antigen 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_057520.2|ensembl:ENSG00000025293(gene)|ensembl:ENST00000374012(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016573"(histone acetylation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR019786|interpro:IPR022255|interpro:IPR037915|interpro:IPR041297|interpro:IPR043449|mint:Q9BVI0|rcsb pdb:2LDM|rcsb pdb:3P8D|rcsb pdb:3Q1J|rcsb pdb:3QII|rcsb pdb:3SD4|rcsb pdb:5TAB|rcsb pdb:5TBN|reactome:R-HSA-3214847|reactome:R-HSA-6804757|reactome:R-HSA-6804759|reactome:R-HSA-69541|refseq:XP_016883353.1|refseq:XP_016883354.1|refseq:XP_016883355.1|refseq:XP_016883356.1|uniprotkb:Q9BVI0(identity)|entrezgene/locuslink:51230(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:xyUU6acdr5R0gcqvCc20L15+lto9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q99832 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|uniprotkb:Q99832(identity)|entrezgene/locuslink:10574(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:P50991 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998|uniprotkb:P50991(identity)|entrezgene/locuslink:10575(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q9C005 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-744973|uniprotkb:D6W578|ensembl:ENSP00000295066|ensembl:ENSP00000345837 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:dpy30_human(display_long)|uniprotkb:DPY30(gene name)|psi-mi:DPY30(display_short)|uniprotkb:Dpy-30-like protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_115963.1|ensembl:ENSG00000162961(gene)|ensembl:ENST00000295066(transcript)|ensembl:ENST00000342166(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006348"|go:"GO:0016197"(endosomal transport)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|mint:Q9C005|rcsb pdb:3G36|rcsb pdb:4RIQ|rcsb pdb:4RT4|rcsb pdb:4RTA|rcsb pdb:6E2H|rcsb pdb:6PWV|reactome:R-HSA-3214841|reactome:R-HSA-8936459|refseq:NP_001308138.1|dip:DIP-34476N|uniprotkb:Q9C005(identity)|entrezgene/locuslink:84661(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:yC9NJhTfEIT+YyfWRSJLGbRsQkc9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q969R5 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750|uniprotkb:Q969R5(identity)|entrezgene/locuslink:83746(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q9UMN6 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-765774|uniprotkb:O15022|uniprotkb:O95836|uniprotkb:Q96GP2|uniprotkb:Q96IP3|uniprotkb:Q9UK25|uniprotkb:Q9Y668|uniprotkb:Q9Y669|ensembl:ENSP00000398837 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:kmt2b_human(display_long)|uniprotkb:KMT2B(gene name)|psi-mi:KMT2B(display_short)|uniprotkb:HRX2(gene name synonym)|uniprotkb:KIAA0304(gene name synonym)|uniprotkb:MLL2(gene name synonym)|uniprotkb:MLL4(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 4(gene name synonym)|uniprotkb:TRX2(gene name synonym)|uniprotkb:Trithorax homolog 2(gene name synonym)|uniprotkb:WBP7(gene name synonym)|uniprotkb:WW domain-binding protein 7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) ensembl:ENSP00000398837|dip:DIP-34598N|ensembl:ENSG00000272333(gene)|ensembl:ENST00000420124(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR001214(SET)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036427|interpro:IPR041959|mint:Q9UMN6|rcsb pdb:3UVM|rcsb pdb:4ERZ|rcsb pdb:4PZI|rcsb pdb:7BRE|reactome:R-HSA-3214841|reactome:R-HSA-8936459|uniprotkb:Q9UMN6(identity)|entrezgene/locuslink:9757(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:1Im1Dqkyg85ZGqrxLaK4wyMVGNY9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q96ES7 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-743117|ensembl:ENSP00000316114|uniprotkb:Q96MF5 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:sgf29_human(display_long)|uniprotkb:SGF29(gene name)|psi-mi:SGF29(display_short)|uniprotkb:CCDC101(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 101(gene name synonym)|uniprotkb:SAGA complex-associated factor 29(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) ensembl:ENSG00000176476(gene)|ensembl:ENST00000317058(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0071169"(establishment of protein localization to chromatin)|interpro:IPR010750(Protein of unknown function DUF1325)|interpro:IPR037802|mint:Q96ES7|rcsb pdb:3LX7|rcsb pdb:3ME9|refseq:NP_612423.1|rcsb pdb:3MEA|rcsb pdb:3MET|rcsb pdb:3MEU|rcsb pdb:3MEV|rcsb pdb:3MEW|rcsb pdb:5C0M|reactome:R-HSA-3214847|uniprotkb:Q96ES7(identity)|entrezgene/locuslink:112869(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:4uvy31cdeHtlQ4BHWSOLE8Szkq49606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q14186 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|entrezgene/locuslink:7027(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q8NFC6 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-2654318|uniprotkb:Q9NTD6|uniprotkb:Q96AL1|uniprotkb:Q9H6G0|uniprotkb:Q6P0M8|uniprotkb:Q9P2L9|ensembl:ENSP00000040738 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:bd1l1_human(display_long)|uniprotkb:BOD1L1(gene name)|psi-mi:BOD1L1(display_short)|uniprotkb:BOD1L(gene name synonym)|uniprotkb:FAM44A(gene name synonym)|uniprotkb:KIAA1327(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_683692.2|ensembl:ENSG00000038219(gene)|ensembl:ENST00000040738(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR043244|mint:Q8NFC6|uniprotkb:Q8NFC6(identity)|entrezgene/locuslink:259282(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:/sFfw7CP8rOZG3hZNsT0npwIZIQ9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q9Y5Z7 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-592728|uniprotkb:B2R8Q5|uniprotkb:C0H5X3|ensembl:ENSP00000229330 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:hcfc2_human(display_long)|uniprotkb:C2 factor(gene name synonym)|uniprotkb:HCFC2(gene name)|psi-mi:HCFC2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_037452.1|ensembl:ENSG00000111727(gene)|ensembl:ENST00000229330(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016032"(viral process)|go:"GO:0016604"(nuclear body)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0071339"(MLL1 complex)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR036116|interpro:IPR037932|interpro:IPR043536|mint:Q9Y5Z7|uniprotkb:Q9Y5Z7(identity)|entrezgene/locuslink:29915(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:ytE7Aid9JO9RWsRpJPpBbylLRXo9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:P58004 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-3939642|uniprotkb:Q96SI5|uniprotkb:Q5T7D0|ensembl:ENSP00000253063|ensembl:ENSP00000496365 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:sesn2_human(display_long)|uniprotkb:SESN2(gene name)|psi-mi:SESN2(display_short)|uniprotkb:SEST2(gene name synonym)|uniprotkb:Hi95(gene name synonym)|uniprotkb:Hypoxia-induced gene(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) ensembl:ENSG00000130766(gene)|ensembl:ENSG00000285069(gene)|ensembl:ENST00000253063(transcript)|ensembl:ENST00000645231(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0009749"(response to glucose)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016684"(oxidoreductase activity, acting on peroxide as acceptor)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032542"(sulfiredoxin activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046323"(glucose import)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071233"(cellular response to leucine)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0098869"(cellular oxidant detoxification)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901031"(regulation of response to reactive oxygen species)|go:"GO:1902010"(negative regulation of translation in response to endoplasmic reticulum stress)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1990253"(cellular response to leucine starvation)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000479"(regulation of cAMP-dependent protein kinase activity)|interpro:IPR006730("PA26 p53-induced protein (sestrin)")|interpro:IPR029032|mint:P58004|rcsb pdb:5CUF|rcsb pdb:5DJ4|rcsb pdb:5T0N|rcsb pdb:6N0M|reactome:R-HSA-5628897|reactome:R-HSA-9639288|go:"GO:0070728"(leucine binding)|refseq:NP_113647.1|dip:DIP-62044N|uniprotkb:P58004(identity)|entrezgene/locuslink:83667(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:VXNFyYSRCJ52PWWODX6OVCBjndk9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q9Y3B7 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-5453723|ensembl:ENSP00000308897|uniprotkb:A8K219|uniprotkb:Q32P46|uniprotkb:Q96Q73|uniprotkb:A6NLT0 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:rm11_human(display_long)|uniprotkb:MRPL11(gene name)|psi-mi:MRPL11(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein uL11m(gene name synonym)|uniprotkb:CGI-113(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) ensembl:ENSG00000174547(gene)|ensembl:ENST00000310999(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|interpro:IPR000911(Ribosomal protein L11)|interpro:IPR006519(Ribosomal protein L11, bacterial-type)|interpro:IPR020783|interpro:IPR020784|interpro:IPR036769|interpro:IPR036796|mint:Q9Y3B7|refseq:NP_057134.1|refseq:NP_733934.1|refseq:NP_733935.1|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6NU3|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|uniprotkb:Q9Y3B7(identity)|entrezgene/locuslink:65003(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:eTr4vzze0vg1fxw97n9C/lXYssU9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q9BYE7 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:P85299 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-1387467|uniprotkb:O75983|uniprotkb:O95695|uniprotkb:Q5BIW2|uniprotkb:Q5EAJ8|uniprotkb:Q5EAJ9|uniprotkb:Q5XKJ6|uniprotkb:Q96RW1|uniprotkb:Q96RW2|uniprotkb:Q9HA49|uniprotkb:Q9HC46|uniprotkb:Q9NSG0|uniprotkb:Q9NVX8|uniprotkb:Q9NXL1|uniprotkb:Q9UH20|uniprotkb:B1AHF6|uniprotkb:B3KP73|uniprotkb:B1AHG5|ensembl:ENSP00000337464 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:prr5_human(display_long)|uniprotkb:PRR5(gene name)|psi-mi:PRR5(display_short)|uniprotkb:PROTOR1(gene name synonym)|uniprotkb:Protein observed with Rictor-1(gene name synonym)|uniprotkb:PP610(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_001017528.1|refseq:NP_001017529.1|refseq:NP_001017530.1|refseq:NP_056181.2|refseq:NP_851850.1|refseq:NP_001185650.1|ensembl:ENSG00000186654(gene)|ensembl:ENST00000336985(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|interpro:IPR013745(HbrB-like)|interpro:IPR016159(Cullin repeat-like)|reactome:R-HSA-1257604|reactome:R-HSA-389357|reactome:R-HSA-5218920|reactome:R-HSA-5674400|reactome:R-HSA-6804757|uniprotkb:P85299(identity)|entrezgene/locuslink:55615(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:gSTomWI1XWwhquEov8801uadLB49606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q06587 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:P54259 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-945980|uniprotkb:Q99495|uniprotkb:Q99621|uniprotkb:Q9UEK7|ensembl:ENSP00000349076|ensembl:ENSP00000379915 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:atn1_human(display_long)|uniprotkb:ATN1(gene name)|psi-mi:ATN1(display_short)|uniprotkb:DRPLA(gene name synonym)|uniprotkb:Dentatorubral-pallidoluysian atrophy protein(gene name synonym)|uniprotkb:D12S755E(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_001007027.1|refseq:NP_001931.2|ensembl:ENSP00000349076|ensembl:ENSP00000379915|dip:DIP-29423N|ensembl:ENSG00000111676(gene)|ensembl:ENST00000356654(transcript)|ensembl:ENST00000396684(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007417"(central nervous system development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR002951(Atrophin)|interpro:IPR017993|mint:P54259|reactome:R-HSA-8943724|uniprotkb:P54259(identity)|entrezgene/locuslink:1822(identity) psi-mi:"MI:0469"(intact) - crc64:B47603486C672637 figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:SX8MuZ4aW8/PJmQl4HqY+NOSxbI9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:P40227 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N|uniprotkb:P40227(identity)|entrezgene/locuslink:908(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q8IYH5 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-2795524|uniprotkb:B7WPC6|uniprotkb:Q6N004|uniprotkb:Q6N070|uniprotkb:Q8IYP0|uniprotkb:Q8IYR1|uniprotkb:Q8TEK4|uniprotkb:Q9Y4U0|ensembl:ENSP00000359837 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:zzz3_human(display_long)|uniprotkb:ZZZ3(gene name)|psi-mi:ZZZ3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_001295166.1|refseq:NP_056349.1|refseq:XP_016856459.1|refseq:XP_005270782.1|refseq:XP_005270783.1|refseq:XP_005270784.1|refseq:XP_005270786.1|ensembl:ENSG00000036549(gene)|ensembl:ENST00000370801(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR037830|interpro:IPR041981|interpro:IPR043145|rcsb pdb:2FC7|rcsb pdb:2YUM|rcsb pdb:6E83|rcsb pdb:6E86|reactome:R-HSA-3214847|mint:Q8IYH5|dip:DIP-47289N|uniprotkb:Q8IYH5(identity)|entrezgene/locuslink:26009(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:F8aEW+XePZMAIrIAIDMEnBXdSBo9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q8IWI9 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-2815196|uniprotkb:E7ENI0|uniprotkb:F5H7K2|uniprotkb:Q9H9N7|uniprotkb:Q9H8R3|uniprotkb:Q9Y4E9|uniprotkb:Q9UG69|intact:EBI-11143500|intact:EBI-10969960|ensembl:ENSP00000219905|uniprotkb:B9EGR5 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:mgap_human(display_long)|uniprotkb:MGA(gene name)|psi-mi:MGA(display_short)|uniprotkb:KIAA0518(gene name synonym)|uniprotkb:MAD5(gene name synonym)|uniprotkb:MAX dimerization protein 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_001074010.2|ensembl:ENSP00000219905|ensembl:ENST00000566586|ensembl:ENSP00000456141|ensembl:ENSG00000174197(gene)|ensembl:ENST00000219905(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR018186|interpro:IPR032060|interpro:IPR036638|interpro:IPR036960|interpro:IPR037935|mint:Q8IWI9|reactome:R-HSA-8953750|refseq:NP_001157745.1|dip:DIP-57615N|uniprotkb:Q8IWI9(identity)|entrezgene/locuslink:23269(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:P4lo9EteCvikQQk5kyVkcobitLU9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q6R327 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-1387196|uniprotkb:Q68DT5|uniprotkb:Q86UB7|uniprotkb:Q8N3A0|uniprotkb:Q8NCM6|uniprotkb:B2RNX0|uniprotkb:B7ZMF7|ensembl:ENSP00000349959 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:rictr_human(display_long)|uniprotkb:RICTOR(gene name)|psi-mi:RICTOR(display_short)|uniprotkb:KIAA1999(gene name synonym)|uniprotkb:AVO3 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_001272368.1|refseq:NP_001272369.1|refseq:NP_689969.2|dip:DIP-39479N|ensembl:ENST00000357387(transcript)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005829"(cytosol)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031932"(TORC2 complex)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0033135"(regulation of peptidyl-serine phosphorylation)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0043022"(ribosome binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028267|interpro:IPR028268|interpro:IPR029259|interpro:IPR029451|interpro:IPR029452|interpro:IPR029453|mint:Q6R327|rcsb pdb:5ZCS|rcsb pdb:6ZWM|rcsb pdb:6ZWO|reactome:R-HSA-1257604|reactome:R-HSA-389357|reactome:R-HSA-5218920|reactome:R-HSA-5674400|reactome:R-HSA-6804757|ensembl:ENSG00000164327(gene)|uniprotkb:Q6R327(identity)|entrezgene/locuslink:253260(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:LlVf8U/ZLBh0fYyzx8RzSpm+1sc9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q9UPS6 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-8836493|uniprotkb:F6MFW1|ensembl:ENSP00000474253|ensembl:ENSP00000481531 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:set1b_human(display_long)|uniprotkb:KIAA1076(gene name synonym)|uniprotkb:KMT2G(gene name synonym)|uniprotkb:Lysine N-methyltransferase 2G(gene name synonym)|uniprotkb:SET domain-containing protein 1B(gene name synonym)|uniprotkb:SET1B(gene name synonym)|uniprotkb:SETD1B(gene name)|psi-mi:SETD1B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_055863.1|ensembl:ENST00000542440|ensembl:ENSP00000442924|ensembl:ENSP00000474253|ensembl:ENSP00000481531|refseq:XP_005253915.1|refseq:XP_006719359.1|dip:DIP-61947N|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR024657|interpro:IPR034468|interpro:IPR035979|interpro:IPR037842|interpro:IPR044570|ensembl:ENSG00000139718(gene)|ensembl:ENST00000604567(transcript)|ensembl:ENST00000619791(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|mint:Q9UPS6|rcsb pdb:3UVO|rcsb pdb:4ES0|reactome:R-HSA-3214841|reactome:R-HSA-8936459|uniprotkb:Q9UPS6(identity)|entrezgene/locuslink:23067(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:ZUY82C1+39tPg4n/f61PDe3DlGo9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q92974 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-302405|intact:EBI-1045693|uniprotkb:O75142|uniprotkb:Q15079|uniprotkb:Q5VY92|uniprotkb:Q8TDA3|uniprotkb:Q8WUG4|uniprotkb:Q9H023|ensembl:ENSP00000354837|uniprotkb:D3DVA6 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:arhg2_human(display_long)|uniprotkb:ARHGEF2(gene name)|psi-mi:ARHGEF2(display_short)|uniprotkb:KIAA0651(gene name synonym)|uniprotkb:LFP40(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor H1(gene name synonym)|uniprotkb:Microtubule-regulated Rho-GEF(gene name synonym)|uniprotkb:Proliferating cell nucleolar antigen p40(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_001155855.1|refseq:NP_001155856.1|refseq:NP_004714.2|ensembl:ENSG00000116584(gene)|ensembl:ENST00000361247(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007015"(actin filament organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007049"(cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR037806|interpro:IPR041020|mint:Q92974|rcsb pdb:5EFX|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045087"(innate immune response)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902219"(negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress)|uniprotkb:Q92974(identity)|entrezgene/locuslink:9181(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:GljUl7uzMi3HaFQsMybfT6KrW089606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:P49368 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N|uniprotkb:P49368(identity)|entrezgene/locuslink:7203(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q9P0U4 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-949911|ensembl:ENSP00000285106|uniprotkb:Q8N2W4|uniprotkb:Q96BC8|uniprotkb:Q9P2V7|uniprotkb:B2RC03 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:cxxc1_human(display_long)|uniprotkb:CFP1(gene name synonym)|uniprotkb:PHD finger and CXXC domain-containing protein 1(gene name synonym)|uniprotkb:CXXC1(gene name)|psi-mi:CXXC1(display_short)|uniprotkb:CGBP(gene name synonym)|uniprotkb:PCCX1(gene name synonym)|uniprotkb:PHF18(gene name synonym)|uniprotkb:CpG-binding protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) ensembl:ENSG00000154832(gene)|ensembl:ENST00000285106(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|reactome:R-HSA-381038|interpro:IPR022056|interpro:IPR037869|mint:Q9P0U4|rcsb pdb:3QMB|rcsb pdb:3QMC|rcsb pdb:3QMD|rcsb pdb:3QMG|rcsb pdb:3QMH|rcsb pdb:3QMI|refseq:NP_001095124.1|refseq:NP_055408.2|refseq:XP_011524242.1|refseq:XP_016881207.1|dip:DIP-50001N|uniprotkb:Q9P0U4(identity)|entrezgene/locuslink:30827(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:nWwPX7OlafdCMD8Qg+hETjNkKgY9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q9NS73 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-741953|uniprotkb:Q86TZ2|uniprotkb:Q96AS5|uniprotkb:Q9BS93|uniprotkb:Q9NZE1|ensembl:ENSP00000399718 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:mbip1_human(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:MBIP(gene name)|psi-mi:MBIP(display_short)|uniprotkb:BM-015(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_001138363.1|refseq:NP_057670.2|ensembl:ENSG00000151332(gene)|ensembl:ENST00000416007(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR026062|mint:Q9NS73|reactome:R-HSA-3214847|go:"GO:0005654"(nucleoplasm)|refseq:NP_001295039.1|uniprotkb:Q9NS73(identity)|entrezgene/locuslink:51562(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:PjaEuab6wwOyGImpNYFZfQ+TUvU9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q14686 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-78670|uniprotkb:A6NLF1|uniprotkb:Q9NTZ9|uniprotkb:Q9UH74|uniprotkb:Q9UK86|ensembl:ENSP00000351894|ensembl:ENSP00000363929|uniprotkb:B2RMN5|uniprotkb:E1P5P7 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:ncoa6_human(display_long)|uniprotkb:NCOA6(gene name)|psi-mi:NCOA6(display_short)|uniprotkb:KIAA0181(gene name synonym)|uniprotkb:RAP250(gene name synonym)|uniprotkb:Amplified in breast cancer protein 3(gene name synonym)|uniprotkb:Cancer-amplified transcriptional coactivator ASC-2(gene name synonym)|uniprotkb:Activating signal cointegrator 2(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-interacting protein(gene name synonym)|uniprotkb:Nuclear receptor-activating protein, 250 kDa(gene name synonym)|uniprotkb:Nuclear receptor coactivator RAP250(gene name synonym)|uniprotkb:Thyroid hormone receptor-binding protein(gene name synonym)|uniprotkb:AIB3(gene name synonym)|uniprotkb:TRBP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_001229468.1|refseq:NP_054790.2|ensembl:ENSG00000198646(gene)|ensembl:ENST00000359003(transcript)|ensembl:ENST00000374796(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0009725"(response to hormone)|go:"GO:0019899"(enzyme binding)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051427"(hormone receptor binding)|interpro:IPR026638|interpro:IPR032715|mint:Q14686|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-5617472|reactome:R-HSA-9707564|reactome:R-HSA-9707616|ensembl:ENSP00000351894|ensembl:ENSP00000363929|refseq:NP_001305169.1|dip:DIP-30934N|uniprotkb:Q14686(identity)|entrezgene/locuslink:23054(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:0PZz93t/oHYDVeiX+8NqjSlpNRo9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:O15047 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-540779|uniprotkb:A6NP62|uniprotkb:Q6PIF3|uniprotkb:Q8TAJ6|intact:EBI-28969638|ensembl:ENSP00000262519|ensembl:ENSP00000507683 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:set1a_human(display_long)|uniprotkb:KMT2F(gene name synonym)|uniprotkb:SET domain-containing protein 1A(gene name synonym)|uniprotkb:Set1/Ash2 histone methyltransferase complex subunit SET1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 2F(gene name synonym)|uniprotkb:SETD1A(gene name)|psi-mi:SETD1A(display_short)|uniprotkb:KIAA0339(gene name synonym)|uniprotkb:SET1(gene name synonym)|uniprotkb:SET1A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_055527.1|refseq:XP_006721169.1|ensembl:ENSP00000262519|ensembl:ENSP00000507683|reactome:R-HSA-8936459|reactome:R-HSA-3214841|ensembl:ENSG00000099381(gene)|ensembl:ENST00000262519(transcript)|ensembl:ENST00000684162(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007420"(brain development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR024657|interpro:IPR034467|interpro:IPR035979|interpro:IPR037841|interpro:IPR044570|mint:O15047|go:"GO:0048188"(Set1C/COMPASS complex)|rcsb pdb:3S8S|rcsb pdb:3UVN|rcsb pdb:4EWR|refseq:XP_005255780.1|refseq:XP_016879398.1|dip:DIP-33494N|uniprotkb:O15047(identity)|entrezgene/locuslink:9739(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:nx0uWEVFas1w2NmuG73lCObAULE9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q7Z3B3 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-740244|uniprotkb:Q6AW85|uniprotkb:Q8IYH1|uniprotkb:Q9BRH0|uniprotkb:Q9NTE7|uniprotkb:Q9UFT0|uniprotkb:Q9ULF3|uniprotkb:A8K5E4|ensembl:ENSP00000262419|ensembl:ENSP00000387393|ensembl:ENSP00000461484|ensembl:ENSP00000461812|intact:EBI-10178305|uniprotkb:B3KT49|uniprotkb:I3L4J3 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:kanl1_human(display_long)|uniprotkb:KANSL1(gene name)|psi-mi:KANSL1(display_short)|uniprotkb:KIAA1267(gene name synonym)|uniprotkb:MLL1/MLL complex subunit KANSL1(gene name synonym)|uniprotkb:MSL1 homolog 1(gene name synonym)|uniprotkb:MSL1V1(gene name synonym)|uniprotkb:NSL complex protein NSL1(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Non-specific lethal 1 homolog(gene name synonym)|uniprotkb:CENP-36(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_001180394.1|refseq:NP_001180395.1|refseq:NP_056258.1|refseq:XP_006721886.1|ensembl:ENSG00000120071(gene)|ensembl:ENST00000262419(transcript)|ensembl:ENST00000432791(transcript)|ensembl:ENST00000572904(transcript)|ensembl:ENST00000574590(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0071339"(MLL1 complex)|interpro:IPR026180|interpro:IPR029332|mint:Q7Z3B3|rcsb pdb:4CY1|rcsb pdb:4CY2|reactome:R-HSA-3214847|refseq:XP_006721887.1|uniprotkb:Q7Z3B3(identity)|entrezgene/locuslink:284058(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:Co/MKm4PZcwn3BUf6ZKYOqW0VhA9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:O15530 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-717097|uniprotkb:Q8IV52|uniprotkb:Q9BRD5|uniprotkb:Q6FI20|uniprotkb:H0Y4Z0|uniprotkb:Q59EH6|intact:EBI-28968232|ensembl:ENSP00000344220 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:pdpk1_human(display_long)|uniprotkb:PDPK1(gene name)|psi-mi:PDPK1(display_short)|uniprotkb:PDK1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_002604.1|refseq:NP_112558.2|ensembl:ENST00000268673|ensembl:ENSP00000268673|ensembl:ENSP00000344220|ensembl:ENST00000441549|ensembl:ENSP00000395357|refseq:NP_001248745.1|ensembl:ENSG00000140992(gene)|ensembl:ENST00000342085(transcript)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004676"(3-phosphoinositide-dependent protein kinase activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0010518"(positive regulation of phospholipase activity)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042995"(cell projection)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043204"(perikaryon)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043304"(regulation of mast cell degranulation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033931|interpro:IPR039046|rcsb pdb:1H1W|rcsb pdb:1OKY|rcsb pdb:1OKZ|rcsb pdb:1UU3|rcsb pdb:1UU7|rcsb pdb:1UU8|rcsb pdb:1UU9|rcsb pdb:1UVR|rcsb pdb:1W1G|rcsb pdb:1W1H|rcsb pdb:1Z5M|rcsb pdb:2BIY|rcsb pdb:2PE0|rcsb pdb:2PE1|rcsb pdb:2PE2|rcsb pdb:2R7B|rcsb pdb:2VKI|rcsb pdb:2XCH|rcsb pdb:2XCK|rcsb pdb:3H9O|rcsb pdb:3HRC|rcsb pdb:3HRF|rcsb pdb:3ION|rcsb pdb:3IOP|rcsb pdb:3NAX|rcsb pdb:3NAY|rcsb pdb:3NUN|rcsb pdb:3NUS|rcsb pdb:3NUU|rcsb pdb:3NUY|rcsb pdb:3ORX|rcsb pdb:3ORZ|rcsb pdb:3OTU|rcsb pdb:1W1D|rcsb pdb:3PWY|rcsb pdb:3QC4|rcsb pdb:3QCQ|rcsb pdb:3QCS|rcsb pdb:3QCX|rcsb pdb:3QCY|rcsb pdb:3QD0|rcsb pdb:3QD3|rcsb pdb:3QD4|rcsb pdb:3RCJ|rcsb pdb:3RWP|rcsb pdb:3RWQ|rcsb pdb:3SC1|rcsb pdb:4A06|rcsb pdb:4A07|rcsb pdb:4AW0|rcsb pdb:4AW1|rcsb pdb:4CT1|rcsb pdb:4CT2|rcsb pdb:4RQK|rcsb pdb:4RQV|rcsb pdb:4RRV|rcsb pdb:4XX9|rcsb pdb:5ACK|rcsb pdb:5HKM|rcsb pdb:5HNG|rcsb pdb:5HO7|rcsb pdb:5HO8|rcsb pdb:5LVL|rcsb pdb:5LVM|rcsb pdb:5LVN|rcsb pdb:5LVO|rcsb pdb:5LVP|rcsb pdb:5MRD|rcsb pdb:6WJQ|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-165158|reactome:R-HSA-202424|reactome:R-HSA-2730905|reactome:R-HSA-2871837|reactome:R-HSA-354192|reactome:R-HSA-389357|reactome:R-HSA-392451|reactome:R-HSA-444257|reactome:R-HSA-5218920|reactome:R-HSA-5218921|reactome:R-HSA-5607764|reactome:R-HSA-5625740|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-9634635|dip:DIP-38372N|uniprotkb:O15530(identity)|entrezgene/locuslink:5170(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:1Uf7b8GptL7XBfEZm43zB3ho6ZQ9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q8IY57 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|entrezgene/locuslink:10138(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q03164 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-591370|ensembl:ENSP00000374157|uniprotkb:Q13743|uniprotkb:Q13744|uniprotkb:Q14845|uniprotkb:Q16364|uniprotkb:Q6UBD1|uniprotkb:Q9UMA3|intact:EBI-2614650|uniprotkb:Q59FF2|uniprotkb:Q9UD94|uniprotkb:E9PQG7|uniprotkb:Q9HBJ3 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:kmt2a_human(display_long)|uniprotkb:KMT2A(gene name)|psi-mi:KMT2A(display_short)|uniprotkb:ALL-1(gene name synonym)|uniprotkb:ALL1(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 7(gene name synonym)|uniprotkb:CXXC7(gene name synonym)|uniprotkb:HRX(gene name synonym)|uniprotkb:HTRX(gene name synonym)|uniprotkb:MLL(gene name synonym)|uniprotkb:MLL1(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 1(gene name synonym)|uniprotkb:TRX1(gene name synonym)|uniprotkb:Trithorax-like protein(gene name synonym)|uniprotkb:Zinc finger protein HRX(gene name synonym)|uniprotkb:Cysteine methyltransferase KMT2A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) go:"GO:2000615"(regulation of histone H3-K9 acetylation)|interpro:IPR001214(SET)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036427|interpro:IPR037927|interpro:IPR041958|interpro:IPR042023|interpro:IPR042025|interpro:IPR044133|mint:Q03164|rcsb pdb:2AGH|rcsb pdb:2J2S|rcsb pdb:2JYI|rcsb pdb:2KKF|rcsb pdb:2KU7|rcsb pdb:2KYU|rcsb pdb:2LXS|rcsb pdb:2LXT|rcsb pdb:2MSR|rcsb pdb:2MTN|rcsb pdb:2W5Y|ensembl:ENSG00000118058(gene)|ensembl:ENST00000389506(transcript)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071440"(regulation of histone H3-K14 acetylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|go:"GO:1905642"(negative regulation of DNA methylation)|refseq:NP_001184033.1|refseq:NP_005924.2|ensembl:ENSP00000374157|ensembl:ENST00000534358|ensembl:ENSP00000436786|ensembl:ENST00000649699|ensembl:ENSP00000496927|dip:DIP-29221N|rcsb pdb:2W5Z|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3LQH|rcsb pdb:3LQI|rcsb pdb:3LQJ|rcsb pdb:3P4F|rcsb pdb:3U85|rcsb pdb:3U88|rcsb pdb:4ESG|rcsb pdb:4GQ6|rcsb pdb:4NW3|rcsb pdb:5F5E|rcsb pdb:5F6L|rcsb pdb:5SVH|rcsb pdb:6EMQ|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U9K|rcsb pdb:6U9M|rcsb pdb:6U9N|rcsb pdb:6U9R|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|reactome:R-HSA-3214841|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9616222|uniprotkb:Q03164(identity)|entrezgene/locuslink:4297(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:r9J9pjnLZI7GCBSHYqnmzjv9WvM9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:O75478 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-742268|uniprotkb:A8MVD0|uniprotkb:B3KMU9|uniprotkb:Q9UCW2|uniprotkb:Q9UP49|intact:EBI-1204772|uniprotkb:Q9BVJ0|ensembl:ENSP00000481283|ensembl:ENSP00000482484|ensembl:ENSP00000488016 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:tad2a_human(display_long)|uniprotkb:TADA2A(gene name)|psi-mi:TADA2A(display_short)|uniprotkb:TADA2L(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym)|uniprotkb:KL04P(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_001159577.2|refseq:NP_001278847.1|refseq:NP_001479.4|refseq:NP_597683.3|go:"GO:0000125"|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|mint:O75478|rcsb pdb:1X41|reactome:R-HSA-3214847|ensembl:ENST00000633468(transcript)|ensembl:ENSG00000277104(gene)|ensembl:ENST00000617828(transcript)|ensembl:ENST00000622522(transcript)|dip:DIP-28151N|uniprotkb:O75478(identity)|entrezgene/locuslink:6871(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:GoQFsH/fQmhFkH04dCJrMWwZH589606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q9P035 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-359013|intact:EBI-1049123|uniprotkb:A0PJA1|uniprotkb:Q280Z3|uniprotkb:Q6PD63|uniprotkb:Q8IUI5|uniprotkb:Q8NC86|uniprotkb:Q8NCB1|uniprotkb:Q96T12|uniprotkb:Q9NQA7|uniprotkb:B4DRF4|intact:EBI-28973764|ensembl:ENSP00000261875 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:hacd3_human(display_long)|uniprotkb:Butyrate-induced protein 1(gene name synonym)|uniprotkb:PTPLAD1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase-like A domain-containing protein 1(gene name synonym)|uniprotkb:HACD3(gene name)|psi-mi:HACD3(display_short)|uniprotkb:3-hydroxyacyl-CoA dehydratase 3(gene name synonym)|uniprotkb:BIND1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) ensembl:ENSP00000261875|ensembl:ENST00000442729|ensembl:ENSP00000392491|refseq:NP_057479.2|ensembl:ENSG00000074696(gene)|ensembl:ENST00000261875(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005925"(focal adhesion)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0018812"(3-hydroxyacyl-CoA dehydratase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030497"(fatty acid elongation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0102158"(very-long-chain 3-hydroxyacyl-CoA dehydratase activity)|go:"GO:0102343"(3-hydroxy-arachidoyl-CoA dehydratase activity)|go:"GO:0102344"(3-hydroxy-behenoyl-CoA dehydratase activity)|go:"GO:0102345"(3-hydroxy-lignoceroyl-CoA dehydratase activity)|interpro:IPR007052(CS domain)|interpro:IPR007482(Protein-tyrosine phosphatase-like, PTPLA)|interpro:IPR008978(HSP20-like chaperone)|mint:Q9P035|reactome:R-HSA-75876|uniprotkb:Q9P035(identity)|entrezgene/locuslink:51495(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:U31K6H8I2f5j7FRhfHiY0cG4smA9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q9H7Z6 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-896414|uniprotkb:Q659G0|uniprotkb:Q7LC17|uniprotkb:Q8IY59|uniprotkb:Q8WYB4|uniprotkb:Q8WZ14|uniprotkb:Q9HAC5|uniprotkb:Q9NR35|uniprotkb:A8K4Z1|intact:EBI-2560822|uniprotkb:G5E9P2|ensembl:ENSP00000219797|ensembl:ENSP00000456933 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:kat8_human(display_long)|uniprotkb:KAT8(gene name)|psi-mi:KAT8(display_short)|uniprotkb:MOF(gene name synonym)|uniprotkb:PP7073(orf name)|uniprotkb:MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1(gene name synonym)|uniprotkb:MYST1(gene name synonym)|uniprotkb:Lysine acetyltransferase 8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_115564.2|refseq:NP_892003.2|ensembl:ENSG00000103510(gene)|ensembl:ENST00000219797(transcript)|ensembl:ENST00000543774(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000776"(kinetochore)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0043995"("histone acetyltransferase activity (H4-K5 specific)")|go:"GO:0043996"("histone acetyltransferase activity (H4-K8 specific)")|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046972"("histone acetyltransferase activity (H4-K16 specific)")|go:"GO:0071339"(MLL1 complex)|go:"GO:0072487"(MSL complex)|interpro:IPR000953(Chromo domain)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR036388|interpro:IPR037906|interpro:IPR040706|mint:Q9H7Z6|rcsb pdb:2GIV|rcsb pdb:2PQ8|rcsb pdb:2Y0M|rcsb pdb:3QAH|rcsb pdb:3TOA|rcsb pdb:3TOB|rcsb pdb:4DNC|rcsb pdb:5H43|rcsb pdb:5J8C|rcsb pdb:5J8F|rcsb pdb:5WCI|rcsb pdb:6BA2|rcsb pdb:6BA4|rcsb pdb:6CT2|rcsb pdb:6OIN|rcsb pdb:6OIO|rcsb pdb:6OIP|rcsb pdb:6OIQ|rcsb pdb:6OIR|rcsb pdb:6OWH|rcsb pdb:6OWI|rcsb pdb:6PD8|rcsb pdb:6PD9|rcsb pdb:6PDA|rcsb pdb:6PDB|rcsb pdb:6PDC|rcsb pdb:6PDD|rcsb pdb:6PDE|rcsb pdb:6PDF|rcsb pdb:6PDG|rcsb pdb:7CMR|reactome:R-HSA-3214847|uniprotkb:Q9H7Z6(identity)|entrezgene/locuslink:84148(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:CIkEOWd9OuFyigFJ02ORCqVbXHE9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:P68400 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N|uniprotkb:P68400(identity)|entrezgene/locuslink:1457(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q8NG08 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-2857808|uniprotkb:Q4G0T2|uniprotkb:Q9H7L5|uniprotkb:A8K4C9|ensembl:ENSP00000247815|ensembl:ENSP00000443287 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:helb_human(display_long)|uniprotkb:HELB(gene name)|psi-mi:HELB(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_387467.2|refseq:XP_005269291.1|ensembl:ENSG00000127311(gene)|ensembl:ENST00000247815(transcript)|ensembl:ENST00000545134(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903775"(regulation of DNA double-strand break processing)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|interpro:IPR027044|interpro:IPR027417|interpro:IPR027785|uniprotkb:Q8NG08(identity)|entrezgene/locuslink:92797(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:raNaHGVcm41zMDqtYrqtYIDj1l49606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:O14686 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-996065|uniprotkb:O14687|intact:EBI-28986759|ensembl:ENSP00000301067 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:kmt2d_human(display_long)|uniprotkb:KMT2D(gene name)|psi-mi:KMT2D(display_short)|uniprotkb:ALL1-related protein(gene name synonym)|uniprotkb:ALR(gene name synonym)|uniprotkb:MLL2(gene name synonym)|uniprotkb:MLL4(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_003473.3|refseq:XP_006719677.1|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0043627"(response to estrogen)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:1904837"(beta-catenin-TCF complex assembly)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR009071(High mobility group box, HMG)|ensembl:ENSG00000167548(gene)|ensembl:ENST00000301067(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001555"(oocyte growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|interpro:IPR036910|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR037890|interpro:IPR041961|interpro:IPR041964|mint:O14686|rcsb pdb:3UVK|rcsb pdb:4ERQ|rcsb pdb:4Z4P|rcsb pdb:6O7G|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR034732|ensembl:ENSP00000301067|refseq:XP_005269219.1|dip:DIP-37875N|uniprotkb:O14686(identity)|entrezgene/locuslink:8085(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:eaCGHR6OqxzL66VYfOrzBWJApHY9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q96EZ8 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-348259|ensembl:ENSP00000345358|ensembl:ENSP00000448056|uniprotkb:O14742|uniprotkb:O75497|uniprotkb:Q6VN53|uniprotkb:Q7Z372 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:mcrs1_human(display_long)|uniprotkb:MCRS1(gene name)|psi-mi:MCRS1(display_short)|uniprotkb:MSP58(gene name synonym)|uniprotkb:58 kDa microspherule protein(gene name synonym)|uniprotkb:Cell cycle-regulated factor p78(gene name synonym)|uniprotkb:MCRS2(gene name synonym)|uniprotkb:INO80Q(gene name synonym)|uniprotkb:INO80 complex subunit J(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) ensembl:ENSG00000187778(gene)|ensembl:ENST00000343810(transcript)|ensembl:ENST00000550165(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005844"(polysome)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010521"(telomerase inhibitor activity)|go:"GO:0030425"(dendrite)|go:"GO:0031011"(Ino80 complex)|go:"GO:0034046"("poly(G) binding")|go:"GO:0043204"(perikaryon)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR025999|interpro:IPR037912|mint:Q96EZ8|reactome:R-HSA-3214847|go:"GO:0043984"(histone H4-K16 acetylation)|reactome:R-HSA-5689603|reactome:R-HSA-5696394|refseq:NP_001012300.1|refseq:NP_006328.2|refseq:NP_001265270.1|refseq:XP_005268629.1|refseq:XP_016874178.1|refseq:XP_016874179.1|uniprotkb:Q96EZ8(identity)|entrezgene/locuslink:10445(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:b6u2XbKLMDkL1zbLTPBjq9J23Zs9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q13547 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-301834|uniprotkb:Q92534|ensembl:ENSP00000362649 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:hdac1_human(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:RPD3L1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) ensembl:ENSG00000116478(gene)|ensembl:ENST00000373548(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007492"(endoderm development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031000"(response to caffeine)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043044"|go:"GO:0019213"(deacetylase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900221"(regulation of amyloid-beta clearance)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q13547|rcsb pdb:1TYI|rcsb pdb:4BKX|rcsb pdb:5ICN|rcsb pdb:6Z2J|rcsb pdb:6Z2K|rcsb pdb:7AO8|rcsb pdb:7AO9|rcsb pdb:7AOA|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-193670|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-3769402|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-4641265|reactome:R-HSA-6804758|reactome:R-HSA-69205|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9022538|reactome:R-HSA-9022692|go:"GO:0017053"(transcription repressor complex)|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9615017|reactome:R-HSA-9679191|reactome:R-HSA-983231|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:NP_004955.2|dip:DIP-24184N|uniprotkb:Q13547(identity)|entrezgene/locuslink:3065(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:RP+yIBWH55NgoPTY1nKXqeJL/xY9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q9P2N6 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-395317|uniprotkb:A1L184|uniprotkb:Q05BU4|uniprotkb:Q6P3X2|uniprotkb:Q6PJH6|uniprotkb:Q86T19|uniprotkb:Q9H0C9|uniprotkb:Q9H8C9|uniprotkb:Q9HAP8|uniprotkb:Q9NWE5|intact:EBI-2560782|intact:EBI-726977|uniprotkb:Q96L64|ensembl:ENSP00000499674|uniprotkb:D3DXH3|uniprotkb:D3DXH4 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:kanl3_human(display_long)|uniprotkb:KANSL3(gene name)|psi-mi:KANSL3(display_short)|uniprotkb:KIAA1310(gene name synonym)|uniprotkb:NSL complex protein NSL3(gene name synonym)|uniprotkb:NSL3(gene name synonym)|uniprotkb:Non-specific lethal 3 homolog(gene name synonym)|uniprotkb:PRTD(gene name synonym)|uniprotkb:SI1(gene name synonym)|uniprotkb:Serum inhibited-related protein(gene name synonym)|uniprotkb:Testis development protein PRTD(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) ensembl:ENSG00000114982(gene)|ensembl:ENST00000666923(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR026555|interpro:IPR029058|mint:Q9P2N6|reactome:R-HSA-3214847|refseq:NP_001108488.1|refseq:XP_005264041.1|uniprotkb:Q9P2N6(identity)|entrezgene/locuslink:55683(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:939a58MqNe7Tnr1HRhS7YpD6s6I9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:P18077 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-353383|uniprotkb:Q08ES9|uniprotkb:Q9BVN7|ensembl:ENSP00000393393|ensembl:ENSP00000495672 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:rl35a_human(display_long)|uniprotkb:RPL35A(gene name)|psi-mi:RPL35A(display_short)|uniprotkb:Cell growth-inhibiting gene 33 protein(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL33(gene name synonym)|uniprotkb:GIG33(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_000987.2|refseq:NP_001303240.1|ensembl:ENST00000647248(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001780(Ribosomal protein L35Ae)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR018266|interpro:IPR038661|mint:P18077|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|ensembl:ENSG00000182899(gene)|ensembl:ENST00000448864(transcript)|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|uniprotkb:P18077(identity)|entrezgene/locuslink:6165(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:fnUlL17LsiOp3lSkKNsoYO74IQQ9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:P78371 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695|uniprotkb:P78371(identity)|entrezgene/locuslink:10576(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:P50990 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N|uniprotkb:P50990(identity)|entrezgene/locuslink:10694(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:O75461 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:P61513 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-356793|uniprotkb:P12751|intact:EBI-1051378|uniprotkb:Q6FGF5|ensembl:ENSP00000418082 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:rl37a_human(display_long)|uniprotkb:RPL37A(gene name)|psi-mi:RPL37A(display_short)|uniprotkb:Large ribosomal subunit protein eL43(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_000989.1|ensembl:ENSG00000197756(gene)|ensembl:ENST00000491306(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002674(Ribosomal protein L37ae)|interpro:IPR011331(Ribosomal protein L37ae/L37e, core)|interpro:IPR011332(Ribosomal protein, zinc-binding)|mint:P61513|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|uniprotkb:P61513(identity)|entrezgene/locuslink:6168(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:0kwO2cVd99FGF2+5FyWo94C83049606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q6UXN9 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-1176082|uniprotkb:Q8TEB2|uniprotkb:A8K5R5|intact:EBI-2562464|ensembl:ENSP00000296490 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:wdr82_human(display_long)|uniprotkb:Protein TMEM113(gene name synonym)|uniprotkb:TMEM113(gene name synonym)|uniprotkb:WDR82(gene name)|psi-mi:WDR82(display_short)|uniprotkb:Swd2(gene name synonym)|uniprotkb:WDR82A(gene name synonym)|uniprotkb:UNQ9342/PRO34047(orf name) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_079498.2|ensembl:ENSG00000164091(gene)|ensembl:ENST00000296490(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005730"(nucleolus)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|interpro:IPR037867|mint:Q6UXN9|uniprotkb:Q6UXN9(identity)|entrezgene/locuslink:80335(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:0TyKYwpTLd22Cm+ihT1+n0oo12c9606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q5M775 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-350473|uniprotkb:Q5IBP1|uniprotkb:Q5IBP2|uniprotkb:Q5IBP3|uniprotkb:Q5IBP4|uniprotkb:Q5M772|uniprotkb:Q5M773|uniprotkb:Q5M774|uniprotkb:Q86XT8|uniprotkb:Q8N4U4|uniprotkb:Q8WU84|uniprotkb:Q9HCQ3|uniprotkb:B4DHH0|ensembl:ENSP00000261503|ensembl:ENSP00000378898|ensembl:ENSP00000502924|ensembl:ENSP00000503971|ensembl:ENSP00000504211|uniprotkb:B7WNS8|intact:EBI-2556892 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:cytsb_human(display_long)|uniprotkb:Nuclear structure protein 5(gene name synonym)|uniprotkb:Sperm antigen HCMOGT-1(gene name synonym)|uniprotkb:SPECC1(gene name)|psi-mi:SPECC1(display_short)|uniprotkb:CYTSB(gene name synonym)|uniprotkb:Sperm antigen with calponin homology and coiled-coil domains 1(gene name synonym)|uniprotkb:NSP5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_001028725.1|refseq:NP_001028726.1|refseq:NP_001028727.1|refseq:NP_001230367.1|refseq:NP_001230368.1|refseq:NP_690868.3|ensembl:ENSG00000128487(gene)|ensembl:ENST00000261503(transcript)|ensembl:ENST00000395527(transcript)|ensembl:ENST00000677914(transcript)|ensembl:ENST00000679058(transcript)|ensembl:ENST00000679255(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR036872|mint:Q5M775|interpro:IPR001715(Calponin-like actin-binding)|refseq:XP_016880814.1|uniprotkb:Q5M775(identity)|entrezgene/locuslink:92521(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:iF+19RpfJDyn5whTFnPmDxxECz09606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:P17987 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836498|imex:IM-21659-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|ddbj/embl/genbank:BC001635(identity)|entrezgene/locuslink:11091(identity) refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N|uniprotkb:P17987(identity)|entrezgene/locuslink:6950(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606 intact-crc:4A3B84E8CE8542FC|rigid:KcsCwPe1F5VYR14kI9lvvs7IT7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IY57 uniprotkb:Q8NHM5 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 intact:EBI-3955564|uniprotkb:Q1RLM7|uniprotkb:Q8NCI2|uniprotkb:Q96HC7|uniprotkb:Q96SL0|uniprotkb:Q96T03|uniprotkb:Q9NS96|uniprotkb:Q9UF75|ensembl:ENSP00000366271|uniprotkb:A8MRS1 psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:kdm2b_human(display_long)|uniprotkb:KDM2B(gene name)|psi-mi:KDM2B(display_short)|uniprotkb:CXXC2(gene name synonym)|uniprotkb:FBL10(gene name synonym)|uniprotkb:FBXL10(gene name synonym)|uniprotkb:JHDM1B(gene name synonym)|uniprotkb:PCCX2(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 2(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 10(gene name synonym)|uniprotkb:F-box protein FBL10(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 10(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1B(gene name synonym)|uniprotkb:Jumonji domain-containing EMSY-interactor methyltransferase motif protein(gene name synonym)|uniprotkb:Protein-containing CXXC domain 2(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1B(gene name synonym)|uniprotkb:NDY1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836800|imex:IM-21659-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|ddbj/embl/genbank:BC037777(identity)|entrezgene/locuslink:10138(identity) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENST00000377071(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0021555"(midbrain-hindbrain boundary morphogenesis)|go:"GO:0021592"(fourth ventricle development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021678"(third ventricle development)|go:"GO:0021993"(initiation of neural tube closure)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|interpro:IPR041070|interpro:IPR041667|mint:Q8NHM5|rcsb pdb:4O64|rcsb pdb:5JH5|rcsb pdb:6BVA|reactome:R-HSA-3214842|refseq:NP_115979.3|ensembl:ENSG00000089094(gene)|refseq:NP_001005366.1|uniprotkb:Q8NHM5(identity)|entrezgene/locuslink:84678(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 rogid:tnMbfP2oxwaaDyHHAigNt5hx4hM9606 intact-crc:834D9E25F0D7D155|rigid:0vmv1OMstvFB+MT5daGyaptLtnA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IY57 uniprotkb:P67870 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 intact:EBI-348169|ensembl:ENSP00000365025|ensembl:ENSP00000365026|ensembl:ENSP00000365042|ensembl:ENSP00000372919|ensembl:ENSP00000372925|ensembl:ENSP00000382980|ensembl:ENSP00000390900|ensembl:ENSP00000391038|ensembl:ENSP00000393756|ensembl:ENSP00000394855|ensembl:ENSP00000395275|ensembl:ENSP00000400188|ensembl:ENSP00000407018|ensembl:ENSP00000407379|ensembl:ENSP00000409510|ensembl:ENSP00000410802|ensembl:ENSP00000411322|ensembl:ENSP00000412520|ensembl:ENSP00000413469|ensembl:ENSP00000415237|ensembl:ENSP00000415303|uniprotkb:P07312|uniprotkb:P13862|uniprotkb:Q4VX47|intact:EBI-3866975|uniprotkb:B0UXA9 psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:csk2b_human(display_long)|uniprotkb:Phosvitin(gene name synonym)|uniprotkb:Protein G5a(gene name synonym)|uniprotkb:CSNK2B(gene name)|psi-mi:CSNK2B(display_short)|uniprotkb:CK2N(gene name synonym)|uniprotkb:G5A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836800|imex:IM-21659-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|ddbj/embl/genbank:BC037777(identity)|entrezgene/locuslink:10138(identity) ensembl:ENSG00000204435(gene)|ensembl:ENSG00000230700(gene)|ensembl:ENSG00000206406(gene)|ensembl:ENSG00000232960(gene)|ensembl:ENSG00000224398(gene)|ensembl:ENSG00000224774(gene)|ensembl:ENSG00000228875(gene)|ensembl:ENST00000375882(transcript)|ensembl:ENST00000383427(transcript)|ensembl:ENST00000383433(transcript)|ensembl:ENST00000400110(transcript)|ensembl:ENST00000412802(transcript)|ensembl:ENST00000418230(transcript)|ensembl:ENST00000422567(transcript)|ensembl:ENST00000429633(transcript)|ensembl:ENST00000431476(transcript)|ensembl:ENST00000436169(transcript)|ensembl:ENST00000443673(transcript)|ensembl:ENST00000448596(transcript)|ensembl:ENST00000451917(transcript)|ensembl:ENST00000452985(transcript)|ensembl:ENST00000453234(transcript)|ensembl:ENST00000454382(transcript)|ensembl:ENST00000454511(transcript)|ensembl:ENST00000455161(transcript)|ensembl:ENST00000458330(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0007165"(signal transduction)|ensembl:ENST00000375865(transcript)|ensembl:ENST00000375866(transcript)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016363"(nuclear matrix)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0034622"|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|mint:P67870|rcsb pdb:1DS5|rcsb pdb:1JWH|go:"GO:0008134"(transcription factor binding)|rcsb pdb:1QF8|rcsb pdb:3EED|rcsb pdb:4DGL|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6798695|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:6Q38|refseq:NP_001311.3|refseq:NP_001269314.1|dip:DIP-131N|uniprotkb:P67870(identity)|entrezgene/locuslink:1460(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 rogid:ZTHJjCqHg2dE7B+WoSU28VSMuPg9606 intact-crc:834D9E25F0D7D155|rigid:0vmv1OMstvFB+MT5daGyaptLtnA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IY57 uniprotkb:Q92769 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 intact:EBI-301821|uniprotkb:Q5SRI8|uniprotkb:Q5SZ86|uniprotkb:Q8NEH4|uniprotkb:B4DL58|ensembl:ENSP00000430432|uniprotkb:E1P561|uniprotkb:B3KRS5 psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:hdac2_human(display_long)|uniprotkb:HDAC2(gene name)|psi-mi:HDAC2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836800|imex:IM-21659-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|ddbj/embl/genbank:BC037777(identity)|entrezgene/locuslink:10138(identity) go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035094"(response to nicotine)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042220"(response to cocaine)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q92769|rcsb pdb:3MAX|rcsb pdb:4LXZ|rcsb pdb:4LY1|rcsb pdb:5IWG|rcsb pdb:5IX0|rcsb pdb:6G3O|rcsb pdb:6WBW|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000196591(gene)|ensembl:ENST00000519065(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|rcsb pdb:6WHN|rcsb pdb:6WHO|rcsb pdb:6WHQ|rcsb pdb:6WHZ|rcsb pdb:6WI3|rcsb pdb:6XDM|rcsb pdb:6XEB|rcsb pdb:6XEC|rcsb pdb:7KBG|rcsb pdb:7KBH|rcsb pdb:7LTG|rcsb pdb:7LTK|rcsb pdb:7LTL|reactome:R-HSA-193670|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9615017|reactome:R-HSA-9619665|reactome:R-HSA-9679191|reactome:R-HSA-983231|rcsb pdb:6WBZ|refseq:NP_001518.3|dip:DIP-24220N|refseq:XP_011534090.1|refseq:XP_016866288.1|uniprotkb:Q92769(identity)|entrezgene/locuslink:3066(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 rogid:K4PpGz9E9/TrQZsgvrJuc+uYCn89606 intact-crc:834D9E25F0D7D155|rigid:0vmv1OMstvFB+MT5daGyaptLtnA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IY57 uniprotkb:P61962 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836800|imex:IM-21659-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|ddbj/embl/genbank:BC037777(identity)|entrezgene/locuslink:10138(identity) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N|uniprotkb:P61962(identity)|entrezgene/locuslink:10238(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 intact-crc:834D9E25F0D7D155|rigid:0vmv1OMstvFB+MT5daGyaptLtnA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IY57 uniprotkb:Q14186 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836800|imex:IM-21659-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|ddbj/embl/genbank:BC037777(identity)|entrezgene/locuslink:10138(identity) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222|uniprotkb:Q14186(identity)|entrezgene/locuslink:7027(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 intact-crc:834D9E25F0D7D155|rigid:0vmv1OMstvFB+MT5daGyaptLtnA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IY57 uniprotkb:Q96CS4 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 intact:EBI-4395570|uniprotkb:Q658J5|ensembl:ENSP00000287461 psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:zn689_human(display_long)|uniprotkb:ZNF689(gene name)|psi-mi:ZNF689(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836800|imex:IM-21659-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|ddbj/embl/genbank:BC037777(identity)|entrezgene/locuslink:10138(identity) refseq:NP_612456.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|ensembl:ENSG00000156853(gene)|ensembl:ENST00000287461(transcript)|uniprotkb:Q96CS4(identity)|entrezgene/locuslink:115509(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 rogid:Pu6f7CUHQ9L6Ovrx4lDRoWm5mGA9606 intact-crc:834D9E25F0D7D155|rigid:0vmv1OMstvFB+MT5daGyaptLtnA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IY57 uniprotkb:Q969R5 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836800|imex:IM-21659-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|ddbj/embl/genbank:BC037777(identity)|entrezgene/locuslink:10138(identity) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750|uniprotkb:Q969R5(identity)|entrezgene/locuslink:83746(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 intact-crc:834D9E25F0D7D155|rigid:0vmv1OMstvFB+MT5daGyaptLtnA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IY57 uniprotkb:P61244 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836800|imex:IM-21659-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|ddbj/embl/genbank:BC037777(identity)|entrezgene/locuslink:10138(identity) refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750|uniprotkb:P61244(identity)|entrezgene/locuslink:4149(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 rogid:I5d1d/zT353OsLios95yEITNoWU9606 intact-crc:834D9E25F0D7D155|rigid:0vmv1OMstvFB+MT5daGyaptLtnA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IY57 uniprotkb:P63208 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836800|imex:IM-21659-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|ddbj/embl/genbank:BC037777(identity)|entrezgene/locuslink:10138(identity) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N|uniprotkb:P63208(identity)|entrezgene/locuslink:6500(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 intact-crc:834D9E25F0D7D155|rigid:0vmv1OMstvFB+MT5daGyaptLtnA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IY57 uniprotkb:Q99496 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836800|imex:IM-21659-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|ddbj/embl/genbank:BC037777(identity)|entrezgene/locuslink:10138(identity) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:Q99496(identity)|entrezgene/locuslink:6045(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 intact-crc:834D9E25F0D7D155|rigid:0vmv1OMstvFB+MT5daGyaptLtnA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IY57 uniprotkb:P19784 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 intact:EBI-347451|ensembl:ENSP00000262506 psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836800|imex:IM-21659-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|ddbj/embl/genbank:BC037777(identity)|entrezgene/locuslink:10138(identity) refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|uniprotkb:P19784(identity)|entrezgene/locuslink:1459(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 intact-crc:834D9E25F0D7D155|rigid:0vmv1OMstvFB+MT5daGyaptLtnA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IY57 uniprotkb:O75461 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836800|imex:IM-21659-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|ddbj/embl/genbank:BC037777(identity)|entrezgene/locuslink:10138(identity) refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198|uniprotkb:O75461(identity)|entrezgene/locuslink:1876(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 intact-crc:834D9E25F0D7D155|rigid:0vmv1OMstvFB+MT5daGyaptLtnA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IY57 uniprotkb:P35227 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 intact:EBI-2129767|uniprotkb:A6NGD8|ensembl:ENSP00000478517|ensembl:ENSP00000478970|ensembl:ENSP00000482063|ensembl:ENSP00000482815|ensembl:ENSP00000488868|ensembl:ENSP00000488872 psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:pcgf2_human(display_long)|uniprotkb:PCGF2(gene name)|psi-mi:PCGF2(display_short)|uniprotkb:MEL18(gene name synonym)|uniprotkb:RNF110(gene name synonym)|uniprotkb:ZNF144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836800|imex:IM-21659-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|ddbj/embl/genbank:BC037777(identity)|entrezgene/locuslink:10138(identity) refseq:NP_009075.1|refseq:XP_016880505.1|refseq:XP_005257697.1|refseq:XP_005257698.1|refseq:XP_005257699.1|dip:DIP-41880N|ensembl:ENSG00000277258(gene)|ensembl:ENSG00000278644(gene)|ensembl:ENST00000610440(transcript)|ensembl:ENST00000611883(transcript)|ensembl:ENST00000616199(transcript)|ensembl:ENST00000620225(transcript)|ensembl:ENST00000631566(transcript)|ensembl:ENST00000631610(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35227|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-5617472|reactome:R-HSA-8953750|uniprotkb:P35227(identity)|entrezgene/locuslink:7703(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 rogid:zppw56VrEl6gEFwtJMCN5cQkPxI9606 intact-crc:834D9E25F0D7D155|rigid:0vmv1OMstvFB+MT5daGyaptLtnA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IY57 uniprotkb:Q8IWI9 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 intact:EBI-2815196|uniprotkb:E7ENI0|uniprotkb:F5H7K2|uniprotkb:Q9H9N7|uniprotkb:Q9H8R3|uniprotkb:Q9Y4E9|uniprotkb:Q9UG69|intact:EBI-11143500|intact:EBI-10969960|ensembl:ENSP00000219905|uniprotkb:B9EGR5 psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:mgap_human(display_long)|uniprotkb:MGA(gene name)|psi-mi:MGA(display_short)|uniprotkb:KIAA0518(gene name synonym)|uniprotkb:MAD5(gene name synonym)|uniprotkb:MAX dimerization protein 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836800|imex:IM-21659-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|ddbj/embl/genbank:BC037777(identity)|entrezgene/locuslink:10138(identity) refseq:NP_001074010.2|ensembl:ENSP00000219905|ensembl:ENST00000566586|ensembl:ENSP00000456141|ensembl:ENSG00000174197(gene)|ensembl:ENST00000219905(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR018186|interpro:IPR032060|interpro:IPR036638|interpro:IPR036960|interpro:IPR037935|mint:Q8IWI9|reactome:R-HSA-8953750|refseq:NP_001157745.1|dip:DIP-57615N|uniprotkb:Q8IWI9(identity)|entrezgene/locuslink:23269(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 rogid:P4lo9EteCvikQQk5kyVkcobitLU9606 intact-crc:834D9E25F0D7D155|rigid:0vmv1OMstvFB+MT5daGyaptLtnA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IY57 uniprotkb:Q6W2J9 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836800|imex:IM-21659-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|ddbj/embl/genbank:BC037777(identity)|entrezgene/locuslink:10138(identity) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N|uniprotkb:Q6W2J9(identity)|entrezgene/locuslink:54880(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 intact-crc:834D9E25F0D7D155|rigid:0vmv1OMstvFB+MT5daGyaptLtnA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IY57 uniprotkb:Q9HAH7 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 intact:EBI-2847800|uniprotkb:Q9H9X4|uniprotkb:Q96CI9|uniprotkb:B4DP86|ensembl:ENSP00000287468 psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:fbrs_human(display_long)|uniprotkb:FBRS(gene name)|psi-mi:FBRS(display_short)|uniprotkb:FBS(gene name synonym)|uniprotkb:FBS1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836800|imex:IM-21659-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|ddbj/embl/genbank:BC037777(identity)|entrezgene/locuslink:10138(identity) refseq:NP_001098549.2|dip:DIP-61357N|ensembl:ENSG00000156860(gene)|ensembl:ENST00000287468(transcript)|interpro:IPR023246|mint:Q9HAH7|uniprotkb:Q9HAH7(identity)|entrezgene/locuslink:64319(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 rogid:n1zkWAYdgwY+t7CFWg5RKO1VSfE9606 intact-crc:834D9E25F0D7D155|rigid:0vmv1OMstvFB+MT5daGyaptLtnA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IY57 uniprotkb:Q9BYE7 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836800|imex:IM-21659-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|ddbj/embl/genbank:BC037777(identity)|entrezgene/locuslink:10138(identity) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N|uniprotkb:Q9BYE7(identity)|entrezgene/locuslink:84108(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 intact-crc:834D9E25F0D7D155|rigid:0vmv1OMstvFB+MT5daGyaptLtnA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IY57 uniprotkb:Q06587 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836800|imex:IM-21659-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|ddbj/embl/genbank:BC037777(identity)|entrezgene/locuslink:10138(identity) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540|uniprotkb:Q06587(identity)|entrezgene/locuslink:6015(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 intact-crc:834D9E25F0D7D155|rigid:0vmv1OMstvFB+MT5daGyaptLtnA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IY57 uniprotkb:P61964 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836800|imex:IM-21659-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|ddbj/embl/genbank:BC037777(identity)|entrezgene/locuslink:10138(identity) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N|uniprotkb:P61964(identity)|entrezgene/locuslink:11091(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 intact-crc:834D9E25F0D7D155|rigid:0vmv1OMstvFB+MT5daGyaptLtnA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IY57 uniprotkb:Q15365 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 intact:EBI-946095|uniprotkb:Q13157|uniprotkb:Q14975|ensembl:ENSP00000305556 psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:pcbp1_human(display_long)|uniprotkb:PCBP1(gene name)|psi-mi:PCBP1(display_short)|uniprotkb:Alpha-CP1(gene name synonym)|uniprotkb:Nucleic acid-binding protein SUB2.3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836800|imex:IM-21659-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|ddbj/embl/genbank:BC037777(identity)|entrezgene/locuslink:10138(identity) refseq:NP_006187.2|dip:DIP-38136N|ensembl:ENSG00000169564(gene)|ensembl:ENST00000303577(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098847"(sequence-specific single stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15365|rcsb pdb:1WVN|rcsb pdb:1ZTG|rcsb pdb:3VKE|reactome:R-HSA-72163|reactome:R-HSA-72203|uniprotkb:Q15365(identity)|entrezgene/locuslink:5093(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 rogid:x72fawo4plQ+ipfqIoREIDHc2bA9606 intact-crc:834D9E25F0D7D155|rigid:0vmv1OMstvFB+MT5daGyaptLtnA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IY57 uniprotkb:Q8WXX7 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 intact:EBI-2875359|ensembl:ENSP00000344087|uniprotkb:L7QET3|uniprotkb:L7QF75|uniprotkb:Q5D049|uniprotkb:Q9Y4F2|uniprotkb:A4D1Y9|uniprotkb:Q6PJU5 psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:auts2_human(display_long)|uniprotkb:AUTS2(gene name)|psi-mi:AUTS2(display_short)|uniprotkb:KIAA0442(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836800|imex:IM-21659-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|ddbj/embl/genbank:BC037777(identity)|entrezgene/locuslink:10138(identity) ensembl:ENSG00000158321(gene)|ensembl:ENST00000342771(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048675"(axon extension)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0097484"(dendrite extension)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR023246|reactome:R-HSA-8939243|refseq:NP_001120703.1|refseq:NP_001120704.1|refseq:NP_056385.1|dip:DIP-61355N|uniprotkb:Q8WXX7(identity)|entrezgene/locuslink:26053(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 rogid:8m3VWlXEISEyVwNmlwDFEEKl4Sg9606 intact-crc:834D9E25F0D7D155|rigid:0vmv1OMstvFB+MT5daGyaptLtnA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IY57 uniprotkb:Q9HCM7 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 intact:EBI-6255777|ensembl:ENSP00000396160|uniprotkb:Q86XQ1 psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:fbsl_human(display_long)|uniprotkb:FBRSL1(gene name)|psi-mi:FBRSL1(display_short)|uniprotkb:AUTS2L(gene name synonym)|uniprotkb:KIAA1545(gene name synonym)|uniprotkb:XTP9(gene name synonym)|uniprotkb:AUTS2-like protein(gene name synonym)|uniprotkb:HBV X-transactivated gene 9 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836800|imex:IM-21659-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|ddbj/embl/genbank:BC037777(identity)|entrezgene/locuslink:10138(identity) ensembl:ENSG00000112787(gene)|ensembl:ENST00000434748(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR023246|refseq:NP_001136113.1|uniprotkb:Q9HCM7(identity)|entrezgene/locuslink:57666(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 rogid:JstP98Bp/L0+GmkLfSdhDHnWmiU9606 intact-crc:834D9E25F0D7D155|rigid:0vmv1OMstvFB+MT5daGyaptLtnA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IY57 uniprotkb:P35226 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851 psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836800|imex:IM-21659-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|ddbj/embl/genbank:BC037777(identity)|entrezgene/locuslink:10138(identity) refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|uniprotkb:P35226(identity)|entrezgene/locuslink:100532731(identity)|entrezgene/locuslink:648(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606 intact-crc:834D9E25F0D7D155|rigid:0vmv1OMstvFB+MT5daGyaptLtnA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IY57 uniprotkb:P83916 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836800|imex:IM-21659-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|ddbj/embl/genbank:BC037777(identity)|entrezgene/locuslink:10138(identity) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|entrezgene/locuslink:10951(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 intact-crc:834D9E25F0D7D155|rigid:0vmv1OMstvFB+MT5daGyaptLtnA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IY57 uniprotkb:P68400 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836800|imex:IM-21659-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|ddbj/embl/genbank:BC037777(identity)|entrezgene/locuslink:10138(identity) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N|uniprotkb:P68400(identity)|entrezgene/locuslink:1457(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 intact-crc:834D9E25F0D7D155|rigid:0vmv1OMstvFB+MT5daGyaptLtnA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IY57 uniprotkb:Q5H9F3 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 intact:EBI-8833946|uniprotkb:Q5H9F4|uniprotkb:Q9Y528|uniprotkb:Q8TEN3|uniprotkb:B5MDQ8|uniprotkb:Q6ZVE0|uniprotkb:Q5H9F2|ensembl:ENSP00000218147|ensembl:ENSP00000437775 psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:bcorl_human(display_long)|uniprotkb:BCORL1(gene name)|psi-mi:BCORL1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836800|imex:IM-21659-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|ddbj/embl/genbank:BC037777(identity)|entrezgene/locuslink:10138(identity) ensembl:ENSP00000218147|ensembl:ENSP00000437775|refseq:NP_068765.3|dip:DIP-60148N|ensembl:ENSG00000085185(gene)|ensembl:ENST00000218147(transcript)|ensembl:ENST00000540052(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q5H9F3|rcsb pdb:4HPM|rcsb pdb:5JH5|uniprotkb:Q5H9F3(identity)|entrezgene/locuslink:63035(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 rogid:uQdpjjO3QnnX19nR1Ky76HjCdhw9606 intact-crc:834D9E25F0D7D155|rigid:0vmv1OMstvFB+MT5daGyaptLtnA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IY57 uniprotkb:Q3KNV8 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 intact:EBI-2339807|uniprotkb:O15262|uniprotkb:D3DVN1|ensembl:ENSP00000354724|ensembl:ENSP00000420489 psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:pcgf3_human(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836800|imex:IM-21659-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|ddbj/embl/genbank:BC037777(identity)|entrezgene/locuslink:10138(identity) refseq:NP_006306.2|refseq:NP_001304765.1|dip:DIP-52782N|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q3KNV8|uniprotkb:Q3KNV8(identity)|entrezgene/locuslink:10336(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606 intact-crc:834D9E25F0D7D155|rigid:0vmv1OMstvFB+MT5daGyaptLtnA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IY57 uniprotkb:Q13185 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836800|imex:IM-21659-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|ddbj/embl/genbank:BC037777(identity)|entrezgene/locuslink:10138(identity) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 intact-crc:834D9E25F0D7D155|rigid:0vmv1OMstvFB+MT5daGyaptLtnA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IY57 uniprotkb:Q86SE9 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492 psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836800|imex:IM-21659-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|ddbj/embl/genbank:BC037777(identity)|entrezgene/locuslink:10138(identity) refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N|uniprotkb:Q86SE9(identity)|entrezgene/locuslink:84333(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606 intact-crc:834D9E25F0D7D155|rigid:0vmv1OMstvFB+MT5daGyaptLtnA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IY57 uniprotkb:Q9BSM1 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836800|imex:IM-21659-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N|uniprotkb:Q8IY57(identity)|ddbj/embl/genbank:BC037777(identity)|entrezgene/locuslink:10138(identity) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5|uniprotkb:Q9BSM1(identity)|entrezgene/locuslink:84759(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2019/07/08 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 intact-crc:834D9E25F0D7D155|rigid:0vmv1OMstvFB+MT5daGyaptLtnA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6AHZ1 uniprotkb:Q9UBI6 intact:EBI-2813764|uniprotkb:O15044|uniprotkb:A0PJI5|uniprotkb:Q32MP4|ensembl:ENSP00000479684|ensembl:ENSP00000481657|ensembl:ENSP00000485614 intact:EBI-358636|uniprotkb:Q9BRV5|ensembl:ENSP00000360021|uniprotkb:Q69YP5 psi-mi:z518a_human(display_long)|uniprotkb:ZNF518A(gene name)|psi-mi:ZNF518A(display_short)|uniprotkb:KIAA0335(gene name synonym)|uniprotkb:ZNF518(gene name synonym) psi-mi:gbg12_human(display_long)|uniprotkb:GNG12(gene name)|psi-mi:GNG12(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836931|imex:IM-21659-61 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011538715.1|refseq:XP_011538717.1|refseq:XP_011538720.1|refseq:XP_011538721.1|refseq:XP_011538708.1|refseq:XP_011538722.1|refseq:XP_011538710.1|refseq:XP_011538712.1|refseq:XP_011538714.1|refseq:NP_055618.2|refseq:NP_001317661.1|refseq:NP_001317662.1|refseq:NP_001317663.1|refseq:NP_001317664.1|refseq:NP_001317665.1|refseq:NP_001317666.1|refseq:NP_001317667.1|refseq:XP_016872475.1|refseq:XP_016872478.1|refseq:XP_016872481.1|refseq:XP_016872483.1|refseq:XP_016872486.1|refseq:XP_016872487.1|refseq:XP_016872488.1|ensembl:ENSG00000177853(gene)|ensembl:ENST00000316045(transcript)|ensembl:ENST00000614149(transcript)|ensembl:ENST00000624776(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027760|interpro:IPR036236|refseq:NP_001265453.1|refseq:NP_001265454.1|refseq:NP_001265455.1|uniprotkb:Q6AHZ1(identity)|ddbj/embl/genbank:BC109045(identity)|entrezgene/locuslink:9849(identity) refseq:NP_061329.3|ensembl:ENSG00000172380(gene)|ensembl:ENST00000370982(transcript)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031680"(G-protein beta/gamma-subunit complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001770(G-protein, gamma subunit)|interpro:IPR015898(G-protein, gamma-like subunit)|interpro:IPR036284|reactome:R-HSA-1296041|reactome:R-HSA-163359|reactome:R-HSA-202040|reactome:R-HSA-381676|reactome:R-HSA-392170|reactome:R-HSA-392451|reactome:R-HSA-392851|reactome:R-HSA-400042|reactome:R-HSA-4086398|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-418217|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-428930|reactome:R-HSA-432040|reactome:R-HSA-456926|reactome:R-HSA-500657|reactome:R-HSA-6814122|reactome:R-HSA-8964315|reactome:R-HSA-8964616|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-997272|refseq:XP_016857298.1|refseq:XP_016857299.1|refseq:XP_016857300.1|uniprotkb:Q9UBI6(identity)|entrezgene/locuslink:55970(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:UjGW18sLz9JzoM8943TK/3P5VpY9606 rogid:rCPylE+1WWtdSzfdOd61jXbvM9M9606 intact-crc:4CCD49D4A0DE5E51|rigid:MmWBWa+xIOFl12bByPZTk7eXUZE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6AHZ1 uniprotkb:O14950 intact:EBI-2813764|uniprotkb:O15044|uniprotkb:A0PJI5|uniprotkb:Q32MP4|ensembl:ENSP00000479684|ensembl:ENSP00000481657|ensembl:ENSP00000485614 intact:EBI-1642165|uniprotkb:D3DUH6|intact:EBI-2826593|uniprotkb:Q7Z5Z4|uniprotkb:Q13182|ensembl:ENSP00000237500|ensembl:ENSP00000383037|ensembl:ENSP00000463559|ensembl:ENSP00000464464|ensembl:ENSP00000496809 psi-mi:z518a_human(display_long)|uniprotkb:ZNF518A(gene name)|psi-mi:ZNF518A(display_short)|uniprotkb:KIAA0335(gene name synonym)|uniprotkb:ZNF518(gene name synonym) psi-mi:ml12b_human(display_long)|uniprotkb:MYL12B(gene name)|psi-mi:MYL12B(display_short)|uniprotkb:MRLC2(gene name synonym)|uniprotkb:Myosin regulatory light chain 2-B, smooth muscle isoform(gene name synonym)|uniprotkb:MLC-2A(gene name synonym)|uniprotkb:SHUJUN-1(gene name synonym)|uniprotkb:MYLC2B(gene name synonym)|uniprotkb:Myosin regulatory light chain MRLC2(gene name synonym)|uniprotkb:Myosin regulatory light chain 20 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836931|imex:IM-21659-61 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011538715.1|refseq:XP_011538717.1|refseq:XP_011538720.1|refseq:XP_011538721.1|refseq:XP_011538708.1|refseq:XP_011538722.1|refseq:XP_011538710.1|refseq:XP_011538712.1|refseq:XP_011538714.1|refseq:NP_055618.2|refseq:NP_001317661.1|refseq:NP_001317662.1|refseq:NP_001317663.1|refseq:NP_001317664.1|refseq:NP_001317665.1|refseq:NP_001317666.1|refseq:NP_001317667.1|refseq:XP_016872475.1|refseq:XP_016872478.1|refseq:XP_016872481.1|refseq:XP_016872483.1|refseq:XP_016872486.1|refseq:XP_016872487.1|refseq:XP_016872488.1|ensembl:ENSG00000177853(gene)|ensembl:ENST00000316045(transcript)|ensembl:ENST00000614149(transcript)|ensembl:ENST00000624776(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027760|interpro:IPR036236|refseq:NP_001265453.1|refseq:NP_001265454.1|refseq:NP_001265455.1|uniprotkb:Q6AHZ1(identity)|ddbj/embl/genbank:BC109045(identity)|entrezgene/locuslink:9849(identity) refseq:NP_001138416.1|refseq:NP_001138417.1|refseq:NP_291024.1|refseq:NP_001289978.1|ensembl:ENSG00000118680(gene)|ensembl:ENST00000237500(transcript)|ensembl:ENST00000400175(transcript)|ensembl:ENST00000581193(transcript)|ensembl:ENST00000584539(transcript)|ensembl:ENST00000648965(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016460"(myosin II complex)|go:"GO:0030018"(Z disc)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR015070(Region of unknown function DUF1880)|interpro:IPR018247|mint:O14950|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|uniprotkb:O14950(identity)|entrezgene/locuslink:103910(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:UjGW18sLz9JzoM8943TK/3P5VpY9606 rogid:5jOP3J5TW0eU9zwalQ2S4Oist4k9606 intact-crc:4CCD49D4A0DE5E51|rigid:MmWBWa+xIOFl12bByPZTk7eXUZE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6AHZ1 uniprotkb:P55884 intact:EBI-2813764|uniprotkb:O15044|uniprotkb:A0PJI5|uniprotkb:Q32MP4|ensembl:ENSP00000479684|ensembl:ENSP00000481657|ensembl:ENSP00000485614 intact:EBI-366696|uniprotkb:Q2NL77|uniprotkb:Q9UMF9|uniprotkb:A4D208|ensembl:ENSP00000354125|ensembl:ENSP00000380206 psi-mi:z518a_human(display_long)|uniprotkb:ZNF518A(gene name)|psi-mi:ZNF518A(display_short)|uniprotkb:KIAA0335(gene name synonym)|uniprotkb:ZNF518(gene name synonym) psi-mi:eif3b_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 9(gene name synonym)|uniprotkb:eIF-3-eta(gene name synonym)|uniprotkb:eIF3 p116(gene name synonym)|uniprotkb:eIF3 p110(gene name synonym)|uniprotkb:Prt1 homolog(gene name synonym)|uniprotkb:EIF3B(gene name)|psi-mi:EIF3B(display_short)|uniprotkb:EIF3S9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836931|imex:IM-21659-61 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011538715.1|refseq:XP_011538717.1|refseq:XP_011538720.1|refseq:XP_011538721.1|refseq:XP_011538708.1|refseq:XP_011538722.1|refseq:XP_011538710.1|refseq:XP_011538712.1|refseq:XP_011538714.1|refseq:NP_055618.2|refseq:NP_001317661.1|refseq:NP_001317662.1|refseq:NP_001317663.1|refseq:NP_001317664.1|refseq:NP_001317665.1|refseq:NP_001317666.1|refseq:NP_001317667.1|refseq:XP_016872475.1|refseq:XP_016872478.1|refseq:XP_016872481.1|refseq:XP_016872483.1|refseq:XP_016872486.1|refseq:XP_016872487.1|refseq:XP_016872488.1|ensembl:ENSG00000177853(gene)|ensembl:ENST00000316045(transcript)|ensembl:ENST00000614149(transcript)|ensembl:ENST00000624776(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027760|interpro:IPR036236|refseq:NP_001265453.1|refseq:NP_001265454.1|refseq:NP_001265455.1|uniprotkb:Q6AHZ1(identity)|ddbj/embl/genbank:BC109045(identity)|entrezgene/locuslink:9849(identity) refseq:NP_001032360.1|refseq:NP_003742.2|refseq:XP_011513901.1|refseq:XP_011513902.1|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|ensembl:ENSG00000106263(gene)|ensembl:ENST00000360876(transcript)|ensembl:ENST00000397011(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0045202"(synapse)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR011400(Translation initiation factor eIF-3b)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR034363|interpro:IPR035979|mint:P55884|rcsb pdb:2KRB|rcsb pdb:2NLW|rcsb pdb:5K1H|rcsb pdb:6YBT|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:XP_016868241.1|dip:DIP-31113N|uniprotkb:P55884(identity)|entrezgene/locuslink:8662(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:UjGW18sLz9JzoM8943TK/3P5VpY9606 rogid:MxQFPvmuOcO/S+4NqzToozWr8K89606 intact-crc:4CCD49D4A0DE5E51|rigid:MmWBWa+xIOFl12bByPZTk7eXUZE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6AHZ1 uniprotkb:P45973 intact:EBI-2813764|uniprotkb:O15044|uniprotkb:A0PJI5|uniprotkb:Q32MP4|ensembl:ENSP00000479684|ensembl:ENSP00000481657|ensembl:ENSP00000485614 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 psi-mi:z518a_human(display_long)|uniprotkb:ZNF518A(gene name)|psi-mi:ZNF518A(display_short)|uniprotkb:KIAA0335(gene name synonym)|uniprotkb:ZNF518(gene name synonym) psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836931|imex:IM-21659-61 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011538715.1|refseq:XP_011538717.1|refseq:XP_011538720.1|refseq:XP_011538721.1|refseq:XP_011538708.1|refseq:XP_011538722.1|refseq:XP_011538710.1|refseq:XP_011538712.1|refseq:XP_011538714.1|refseq:NP_055618.2|refseq:NP_001317661.1|refseq:NP_001317662.1|refseq:NP_001317663.1|refseq:NP_001317664.1|refseq:NP_001317665.1|refseq:NP_001317666.1|refseq:NP_001317667.1|refseq:XP_016872475.1|refseq:XP_016872478.1|refseq:XP_016872481.1|refseq:XP_016872483.1|refseq:XP_016872486.1|refseq:XP_016872487.1|refseq:XP_016872488.1|ensembl:ENSG00000177853(gene)|ensembl:ENST00000316045(transcript)|ensembl:ENST00000614149(transcript)|ensembl:ENST00000624776(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027760|interpro:IPR036236|refseq:NP_001265453.1|refseq:NP_001265454.1|refseq:NP_001265455.1|uniprotkb:Q6AHZ1(identity)|ddbj/embl/genbank:BC109045(identity)|entrezgene/locuslink:9849(identity) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|entrezgene/locuslink:23468(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:UjGW18sLz9JzoM8943TK/3P5VpY9606 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 intact-crc:4CCD49D4A0DE5E51|rigid:MmWBWa+xIOFl12bByPZTk7eXUZE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6AHZ1 uniprotkb:P01040 intact:EBI-2813764|uniprotkb:O15044|uniprotkb:A0PJI5|uniprotkb:Q32MP4|ensembl:ENSP00000479684|ensembl:ENSP00000481657|ensembl:ENSP00000485614 intact:EBI-724303|ensembl:ENSP00000264474|uniprotkb:Q6IB90 psi-mi:z518a_human(display_long)|uniprotkb:ZNF518A(gene name)|psi-mi:ZNF518A(display_short)|uniprotkb:KIAA0335(gene name synonym)|uniprotkb:ZNF518(gene name synonym) psi-mi:cyta_human(display_long)|uniprotkb:Cystatin-AS(gene name synonym)|uniprotkb:Stefin-A(gene name synonym)|uniprotkb:CSTA(gene name)|psi-mi:CSTA(display_short)|uniprotkb:STF1(gene name synonym)|uniprotkb:STFA(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836931|imex:IM-21659-61 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011538715.1|refseq:XP_011538717.1|refseq:XP_011538720.1|refseq:XP_011538721.1|refseq:XP_011538708.1|refseq:XP_011538722.1|refseq:XP_011538710.1|refseq:XP_011538712.1|refseq:XP_011538714.1|refseq:NP_055618.2|refseq:NP_001317661.1|refseq:NP_001317662.1|refseq:NP_001317663.1|refseq:NP_001317664.1|refseq:NP_001317665.1|refseq:NP_001317666.1|refseq:NP_001317667.1|refseq:XP_016872475.1|refseq:XP_016872478.1|refseq:XP_016872481.1|refseq:XP_016872483.1|refseq:XP_016872486.1|refseq:XP_016872487.1|refseq:XP_016872488.1|ensembl:ENSG00000177853(gene)|ensembl:ENST00000316045(transcript)|ensembl:ENST00000614149(transcript)|ensembl:ENST00000624776(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027760|interpro:IPR036236|refseq:NP_001265453.1|refseq:NP_001265454.1|refseq:NP_001265455.1|uniprotkb:Q6AHZ1(identity)|ddbj/embl/genbank:BC109045(identity)|entrezgene/locuslink:9849(identity) refseq:NP_005204.1|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR001713(Proteinase inhibitor I25A, stefin A)|mint:P01040|rcsb pdb:1CYU|rcsb pdb:1CYV|rcsb pdb:1DVC|rcsb pdb:1DVD|rcsb pdb:1GD3|rcsb pdb:1GD4|rcsb pdb:1N9J|rcsb pdb:1NB3|rcsb pdb:1NB5|rcsb pdb:3K9M|rcsb pdb:3KFQ|interpro:IPR018073|rcsb pdb:3KSE|reactome:R-HSA-6809371|ensembl:ENSG00000121552(gene)|ensembl:ENST00000264474(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002020"(protease binding)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0045861"(negative regulation of proteolysis)|uniprotkb:P01040(identity)|entrezgene/locuslink:1475(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:UjGW18sLz9JzoM8943TK/3P5VpY9606 rogid:SzbpyWUHlOtItIvffzuwhcqFsDI9606 intact-crc:4CCD49D4A0DE5E51|rigid:MmWBWa+xIOFl12bByPZTk7eXUZE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6AHZ1 uniprotkb:Q13263 intact:EBI-2813764|uniprotkb:O15044|uniprotkb:A0PJI5|uniprotkb:Q32MP4|ensembl:ENSP00000479684|ensembl:ENSP00000481657|ensembl:ENSP00000485614 intact:EBI-78139|uniprotkb:O00677|ensembl:ENSP00000253024|uniprotkb:Q7Z632|uniprotkb:Q93040|uniprotkb:Q96IM1 psi-mi:z518a_human(display_long)|uniprotkb:ZNF518A(gene name)|psi-mi:ZNF518A(display_short)|uniprotkb:KIAA0335(gene name synonym)|uniprotkb:ZNF518(gene name synonym) psi-mi:tif1b_human(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836931|imex:IM-21659-61 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011538715.1|refseq:XP_011538717.1|refseq:XP_011538720.1|refseq:XP_011538721.1|refseq:XP_011538708.1|refseq:XP_011538722.1|refseq:XP_011538710.1|refseq:XP_011538712.1|refseq:XP_011538714.1|refseq:NP_055618.2|refseq:NP_001317661.1|refseq:NP_001317662.1|refseq:NP_001317663.1|refseq:NP_001317664.1|refseq:NP_001317665.1|refseq:NP_001317666.1|refseq:NP_001317667.1|refseq:XP_016872475.1|refseq:XP_016872478.1|refseq:XP_016872481.1|refseq:XP_016872483.1|refseq:XP_016872486.1|refseq:XP_016872487.1|refseq:XP_016872488.1|ensembl:ENSG00000177853(gene)|ensembl:ENST00000316045(transcript)|ensembl:ENST00000614149(transcript)|ensembl:ENST00000624776(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027760|interpro:IPR036236|refseq:NP_001265453.1|refseq:NP_001265454.1|refseq:NP_001265455.1|uniprotkb:Q6AHZ1(identity)|ddbj/embl/genbank:BC109045(identity)|entrezgene/locuslink:9849(identity) ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6QAJ|rcsb pdb:6QU1|reactome:R-HSA-212436|reactome:R-HSA-3899300|reactome:R-HSA-9609690|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q13263|rcsb pdb:1FP0|rcsb pdb:2RO1|rcsb pdb:2YVR|rcsb pdb:6H3A|rcsb pdb:6I9H|refseq:NP_005753.1|dip:DIP-30891N|uniprotkb:Q13263(identity)|entrezgene/locuslink:10155(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:UjGW18sLz9JzoM8943TK/3P5VpY9606 rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606 intact-crc:4CCD49D4A0DE5E51|rigid:MmWBWa+xIOFl12bByPZTk7eXUZE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6AHZ1 uniprotkb:Q13185 intact:EBI-2813764|uniprotkb:O15044|uniprotkb:A0PJI5|uniprotkb:Q32MP4|ensembl:ENSP00000479684|ensembl:ENSP00000481657|ensembl:ENSP00000485614 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:z518a_human(display_long)|uniprotkb:ZNF518A(gene name)|psi-mi:ZNF518A(display_short)|uniprotkb:KIAA0335(gene name synonym)|uniprotkb:ZNF518(gene name synonym) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836931|imex:IM-21659-61 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011538715.1|refseq:XP_011538717.1|refseq:XP_011538720.1|refseq:XP_011538721.1|refseq:XP_011538708.1|refseq:XP_011538722.1|refseq:XP_011538710.1|refseq:XP_011538712.1|refseq:XP_011538714.1|refseq:NP_055618.2|refseq:NP_001317661.1|refseq:NP_001317662.1|refseq:NP_001317663.1|refseq:NP_001317664.1|refseq:NP_001317665.1|refseq:NP_001317666.1|refseq:NP_001317667.1|refseq:XP_016872475.1|refseq:XP_016872478.1|refseq:XP_016872481.1|refseq:XP_016872483.1|refseq:XP_016872486.1|refseq:XP_016872487.1|refseq:XP_016872488.1|ensembl:ENSG00000177853(gene)|ensembl:ENST00000316045(transcript)|ensembl:ENST00000614149(transcript)|ensembl:ENST00000624776(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027760|interpro:IPR036236|refseq:NP_001265453.1|refseq:NP_001265454.1|refseq:NP_001265455.1|uniprotkb:Q6AHZ1(identity)|ddbj/embl/genbank:BC109045(identity)|entrezgene/locuslink:9849(identity) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|entrezgene/locuslink:11335(identity)|uniprotkb:Q13185(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:UjGW18sLz9JzoM8943TK/3P5VpY9606 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 intact-crc:4CCD49D4A0DE5E51|rigid:MmWBWa+xIOFl12bByPZTk7eXUZE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6AHZ1 uniprotkb:P35579 intact:EBI-2813764|uniprotkb:O15044|uniprotkb:A0PJI5|uniprotkb:Q32MP4|ensembl:ENSP00000479684|ensembl:ENSP00000481657|ensembl:ENSP00000485614 intact:EBI-350338|uniprotkb:O60805|ensembl:ENSP00000216181|uniprotkb:Q86T83|intact:EBI-1054343|uniprotkb:A8K6E4|uniprotkb:Q60FE2 psi-mi:z518a_human(display_long)|uniprotkb:ZNF518A(gene name)|psi-mi:ZNF518A(display_short)|uniprotkb:KIAA0335(gene name synonym)|uniprotkb:ZNF518(gene name synonym) psi-mi:myh9_human(display_long)|uniprotkb:MYH9(gene name)|psi-mi:MYH9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836931|imex:IM-21659-61 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011538715.1|refseq:XP_011538717.1|refseq:XP_011538720.1|refseq:XP_011538721.1|refseq:XP_011538708.1|refseq:XP_011538722.1|refseq:XP_011538710.1|refseq:XP_011538712.1|refseq:XP_011538714.1|refseq:NP_055618.2|refseq:NP_001317661.1|refseq:NP_001317662.1|refseq:NP_001317663.1|refseq:NP_001317664.1|refseq:NP_001317665.1|refseq:NP_001317666.1|refseq:NP_001317667.1|refseq:XP_016872475.1|refseq:XP_016872478.1|refseq:XP_016872481.1|refseq:XP_016872483.1|refseq:XP_016872486.1|refseq:XP_016872487.1|refseq:XP_016872488.1|ensembl:ENSG00000177853(gene)|ensembl:ENST00000316045(transcript)|ensembl:ENST00000614149(transcript)|ensembl:ENST00000624776(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027760|interpro:IPR036236|refseq:NP_001265453.1|refseq:NP_001265454.1|refseq:NP_001265455.1|uniprotkb:Q6AHZ1(identity)|ddbj/embl/genbank:BC109045(identity)|entrezgene/locuslink:9849(identity) refseq:NP_002464.1|ensembl:ENSG00000100345(gene)|ensembl:ENST00000216181(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001931"(uropod)|go:"GO:0003723"(RNA binding)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|refseq:XP_011528499.1|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030220"(platelet formation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032418"(lysosome localization)|go:"GO:0032506"(cytokinetic process)|go:"GO:0032796"(uropod organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045296"(cadherin binding)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051015"(actin filament binding)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0097513"(myosin II filament)|go:"GO:1903919"(negative regulation of actin filament severing)|rcsb pdb:4CFR|rcsb pdb:4ETO|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9662834|reactome:R-HSA-9664422|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1905684"(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036305|interpro:IPR036961|mint:P35579|rcsb pdb:2LNK|rcsb pdb:3ZWH|rcsb pdb:4CFQ|refseq:XP_016884292.1|refseq:XP_016884293.1|refseq:XP_016884294.1|refseq:XP_016884295.1|dip:DIP-33103N|uniprotkb:P35579(identity)|entrezgene/locuslink:4627(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:UjGW18sLz9JzoM8943TK/3P5VpY9606 rogid:fSOtpFpr8PSnAG5UdAr/khwkzJs9606 intact-crc:4CCD49D4A0DE5E51|rigid:MmWBWa+xIOFl12bByPZTk7eXUZE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6AHZ1 uniprotkb:Q13561 intact:EBI-2813764|uniprotkb:O15044|uniprotkb:A0PJI5|uniprotkb:Q32MP4|ensembl:ENSP00000479684|ensembl:ENSP00000481657|ensembl:ENSP00000485614 intact:EBI-715074|uniprotkb:Q86YN2|uniprotkb:Q9BW17|uniprotkb:B2RBK5|ensembl:ENSP00000447824 psi-mi:z518a_human(display_long)|uniprotkb:ZNF518A(gene name)|psi-mi:ZNF518A(display_short)|uniprotkb:KIAA0335(gene name synonym)|uniprotkb:ZNF518(gene name synonym) psi-mi:dctn2_human(display_long)|uniprotkb:Dynactin complex 50 kDa subunit(gene name synonym)|uniprotkb:50 kDa dynein-associated polypeptide(gene name synonym)|uniprotkb:p50 dynamitin(gene name synonym)|uniprotkb:DCTN2(gene name)|psi-mi:DCTN2(display_short)|uniprotkb:DCTN50(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836931|imex:IM-21659-61 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011538715.1|refseq:XP_011538717.1|refseq:XP_011538720.1|refseq:XP_011538721.1|refseq:XP_011538708.1|refseq:XP_011538722.1|refseq:XP_011538710.1|refseq:XP_011538712.1|refseq:XP_011538714.1|refseq:NP_055618.2|refseq:NP_001317661.1|refseq:NP_001317662.1|refseq:NP_001317663.1|refseq:NP_001317664.1|refseq:NP_001317665.1|refseq:NP_001317666.1|refseq:NP_001317667.1|refseq:XP_016872475.1|refseq:XP_016872478.1|refseq:XP_016872481.1|refseq:XP_016872483.1|refseq:XP_016872486.1|refseq:XP_016872487.1|refseq:XP_016872488.1|ensembl:ENSG00000177853(gene)|ensembl:ENST00000316045(transcript)|ensembl:ENST00000614149(transcript)|ensembl:ENST00000624776(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027760|interpro:IPR036236|refseq:NP_001265453.1|refseq:NP_001265454.1|refseq:NP_001265455.1|uniprotkb:Q6AHZ1(identity)|ddbj/embl/genbank:BC109045(identity)|entrezgene/locuslink:9849(identity) refseq:NP_006391.1|refseq:NP_001248341.1|refseq:NP_001248342.1|dip:DIP-37545N|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-8854518|ensembl:ENSG00000175203(gene)|ensembl:ENST00000548249(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030286"(dynein complex)|go:"GO:0030426"(growth cone)|go:"GO:0030507"(spectrin binding)|go:"GO:0031982"(vesicle)|go:"GO:0032402"(melanosome transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071539"(protein localization to centrosome)|interpro:IPR028133|mint:Q13561|reactome:R-HSA-2132295|uniprotkb:Q13561(identity)|entrezgene/locuslink:10540(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:UjGW18sLz9JzoM8943TK/3P5VpY9606 rogid:JrL5jUtArek+zqmCkPKomnjuSf09606 intact-crc:4CCD49D4A0DE5E51|rigid:MmWBWa+xIOFl12bByPZTk7eXUZE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VZL5 uniprotkb:Q14202 intact:EBI-2514659|intact:EBI-28984130|ensembl:ENSP00000322915|uniprotkb:A0JP19|uniprotkb:O43308|uniprotkb:A0JP20|uniprotkb:Q5T5E2|uniprotkb:Q7L3Q4|uniprotkb:Q5T5E1|intact:EBI-2556245 intact:EBI-2556139|uniprotkb:O15089|ensembl:ENSP00000322845|uniprotkb:D3DVV3|uniprotkb:Q96E26 psi-mi:zmym4_human(display_long)|uniprotkb:ZMYM4(gene name)|psi-mi:ZMYM4(display_short)|uniprotkb:KIAA0425(gene name synonym)|uniprotkb:ZNF262(gene name synonym)|uniprotkb:Zinc finger protein 262(gene name synonym) psi-mi:zmym3_human(display_long)|uniprotkb:DXS6673E(gene name synonym)|uniprotkb:KIAA0385(gene name synonym)|uniprotkb:ZNF261(gene name synonym)|uniprotkb:Zinc finger protein 261(gene name synonym)|uniprotkb:ZMYM3(gene name)|psi-mi:ZMYM3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836977|imex:IM-21659-62 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000146463(gene)|ensembl:ENST00000314607(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022604"(regulation of cell morphogenesis)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR021893|refseq:XP_016858292.1|refseq:XP_016858293.1|refseq:XP_011540725.1|refseq:XP_011540727.1|refseq:NP_005086.2|ensembl:ENSP00000322915|refseq:XP_005271388.1|uniprotkb:Q5VZL5(identity)|entrezgene/locuslink:9202(identity)|ddbj/embl/genbank:BC127113(identity) refseq:NP_001164633.1|refseq:NP_005087.1|refseq:NP_963893.1|refseq:XP_011529364.1|ensembl:ENSG00000147130(gene)|ensembl:ENST00000314425(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022604"(regulation of cell morphogenesis)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR021893|mint:Q14202|refseq:NP_001164634.1|refseq:XP_005262366.1|refseq:XP_005262367.1|uniprotkb:Q14202(identity)|entrezgene/locuslink:9203(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:jc8YwR+37J3uD08cXiUnOA2hHEI9606 rogid:pNPpauiC3Qk1EB3mevtM9L/+g0A9606 intact-crc:D219E4A3690F9DAD|rigid:H99XHcRZJxW2nT2uP8NyQLsEZZQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VZL5 uniprotkb:Q9UKL0 intact:EBI-2514659|intact:EBI-28984130|ensembl:ENSP00000322915|uniprotkb:A0JP19|uniprotkb:O43308|uniprotkb:A0JP20|uniprotkb:Q5T5E2|uniprotkb:Q7L3Q4|uniprotkb:Q5T5E1|intact:EBI-2556245 intact:EBI-926563|uniprotkb:Q15044|uniprotkb:Q6P2I9|uniprotkb:Q86VG5|intact:EBI-11087913|uniprotkb:J3KN32|ensembl:ENSP00000262241 psi-mi:zmym4_human(display_long)|uniprotkb:ZMYM4(gene name)|psi-mi:ZMYM4(display_short)|uniprotkb:KIAA0425(gene name synonym)|uniprotkb:ZNF262(gene name synonym)|uniprotkb:Zinc finger protein 262(gene name synonym) psi-mi:rcor1_human(display_long)|uniprotkb:RCOR1(gene name)|psi-mi:RCOR1(display_short)|uniprotkb:KIAA0071(gene name synonym)|uniprotkb:RCOR(gene name synonym)|uniprotkb:Protein CoREST(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836977|imex:IM-21659-62 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000146463(gene)|ensembl:ENST00000314607(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022604"(regulation of cell morphogenesis)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR021893|refseq:XP_016858292.1|refseq:XP_016858293.1|refseq:XP_011540725.1|refseq:XP_011540727.1|refseq:NP_005086.2|ensembl:ENSP00000322915|refseq:XP_005271388.1|uniprotkb:Q5VZL5(identity)|entrezgene/locuslink:9202(identity)|ddbj/embl/genbank:BC127113(identity) refseq:NP_055971.2|dip:DIP-35263N|ensembl:ENSG00000089902(gene)|ensembl:ENST00000262241(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0045654"(positive regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:1990391"(DNA repair complex)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|mint:Q9UKL0|rcsb pdb:2IW5|rcsb pdb:2UXN|rcsb pdb:2UXX|rcsb pdb:2V1D|rcsb pdb:2X0L|rcsb pdb:2XAF|rcsb pdb:2XAG|rcsb pdb:2XAH|rcsb pdb:2XAJ|rcsb pdb:2XAQ|rcsb pdb:2XAS|rcsb pdb:2Y48|rcsb pdb:3ZMS|rcsb pdb:3ZMT|rcsb pdb:3ZMU|rcsb pdb:3ZMV|rcsb pdb:3ZMZ|rcsb pdb:3ZN0|rcsb pdb:3ZN1|rcsb pdb:4BAY|rcsb pdb:4KUM|rcsb pdb:4UV8|rcsb pdb:4UV9|rcsb pdb:4UVA|rcsb pdb:4UVB|rcsb pdb:4UVC|rcsb pdb:4UXN|rcsb pdb:4XBF|rcsb pdb:5H6Q|rcsb pdb:5H6R|rcsb pdb:5L3B|rcsb pdb:5L3C|rcsb pdb:5L3D|rcsb pdb:5L3E|rcsb pdb:5L3F|rcsb pdb:5L3G|rcsb pdb:5LBQ|rcsb pdb:5LGN|rcsb pdb:5LGT|rcsb pdb:5LGU|rcsb pdb:5LHG|rcsb pdb:5LHH|rcsb pdb:5LHI|rcsb pdb:5X60|rcsb pdb:5YJB|rcsb pdb:6K3E|rcsb pdb:6KGK|rcsb pdb:6KGL|rcsb pdb:6KGM|rcsb pdb:6KGN|rcsb pdb:6S35|rcsb pdb:6TE1|rcsb pdb:6VYP|rcsb pdb:6W4K|rcsb pdb:6WC6|rcsb pdb:7CDC|rcsb pdb:7CDD|rcsb pdb:7CDE|rcsb pdb:7CDF|rcsb pdb:7CDG|reactome:R-HSA-3214815|reactome:R-HSA-8943724|reactome:R-HSA-9679191|reactome:R-HSA-983231|uniprotkb:Q9UKL0(identity)|entrezgene/locuslink:23186(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:jc8YwR+37J3uD08cXiUnOA2hHEI9606 rogid:B1KfnjicGzKdWGnGGrZwjgpMQ309606 intact-crc:D219E4A3690F9DAD|rigid:H99XHcRZJxW2nT2uP8NyQLsEZZQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VZL5 uniprotkb:P63167 intact:EBI-2514659|intact:EBI-28984130|ensembl:ENSP00000322915|uniprotkb:A0JP19|uniprotkb:O43308|uniprotkb:A0JP20|uniprotkb:Q5T5E2|uniprotkb:Q7L3Q4|uniprotkb:Q5T5E1|intact:EBI-2556245 intact:EBI-349105|uniprotkb:Q15701|ensembl:ENSP00000242577|ensembl:ENSP00000376296|ensembl:ENSP00000376297|ensembl:ENSP00000446614|ensembl:ENSP00000447907 psi-mi:zmym4_human(display_long)|uniprotkb:ZMYM4(gene name)|psi-mi:ZMYM4(display_short)|uniprotkb:KIAA0425(gene name synonym)|uniprotkb:ZNF262(gene name synonym)|uniprotkb:Zinc finger protein 262(gene name synonym) psi-mi:dyl1_human(display_long)|uniprotkb:DYNLL1(gene name)|psi-mi:DYNLL1(display_short)|uniprotkb:DLC1(gene name synonym)|uniprotkb:DNCLC1(gene name synonym)|uniprotkb:HDLC1(gene name synonym)|uniprotkb:Dynein light chain LC8-type 1(gene name synonym)|uniprotkb:8 kDa dynein light chain(gene name synonym)|uniprotkb:Protein inhibitor of neuronal nitric oxide synthase(gene name synonym)|uniprotkb:DNCL1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836977|imex:IM-21659-62 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000146463(gene)|ensembl:ENST00000314607(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022604"(regulation of cell morphogenesis)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR021893|refseq:XP_016858292.1|refseq:XP_016858293.1|refseq:XP_011540725.1|refseq:XP_011540727.1|refseq:NP_005086.2|ensembl:ENSP00000322915|refseq:XP_005271388.1|uniprotkb:Q5VZL5(identity)|entrezgene/locuslink:9202(identity)|ddbj/embl/genbank:BC127113(identity) refseq:NP_001032583.1|refseq:NP_001032584.1|refseq:NP_003737.1|go:"GO:0072686"(mitotic spindle)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:P63167|rcsb pdb:1CMI|rcsb pdb:3ZKE|rcsb pdb:3ZKF|rcsb pdb:6GZJ|rcsb pdb:6GZL|rcsb pdb:6RLB|rcsb pdb:6SC2|rcsb pdb:7D35|reactome:R-HSA-111446|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|go:"GO:0000776"(kinetochore)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0005829"(cytosol)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007286"(spermatid development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030286"(dynein complex)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|ensembl:ENSG00000088986(gene)|ensembl:ENST00000242577(transcript)|ensembl:ENST00000392508(transcript)|ensembl:ENST00000392509(transcript)|ensembl:ENST00000548342(transcript)|ensembl:ENST00000549989(transcript)|dip:DIP-33150N|uniprotkb:P63167(identity)|entrezgene/locuslink:8655(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:jc8YwR+37J3uD08cXiUnOA2hHEI9606 rogid:Bra4LfaqYPMyo6xX9RD6G7Rdv809606 intact-crc:D219E4A3690F9DAD|rigid:H99XHcRZJxW2nT2uP8NyQLsEZZQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VZL5 uniprotkb:Q96FJ2 intact:EBI-2514659|intact:EBI-28984130|ensembl:ENSP00000322915|uniprotkb:A0JP19|uniprotkb:O43308|uniprotkb:A0JP20|uniprotkb:Q5T5E2|uniprotkb:Q7L3Q4|uniprotkb:Q5T5E1|intact:EBI-2556245 intact:EBI-742371|uniprotkb:B2R5B4|ensembl:ENSP00000477310 psi-mi:zmym4_human(display_long)|uniprotkb:ZMYM4(gene name)|psi-mi:ZMYM4(display_short)|uniprotkb:KIAA0425(gene name synonym)|uniprotkb:ZNF262(gene name synonym)|uniprotkb:Zinc finger protein 262(gene name synonym) psi-mi:dyl2_human(display_long)|uniprotkb:DYNLL2(gene name)|psi-mi:DYNLL2(display_short)|uniprotkb:Dynein light chain LC8-type 2(gene name synonym)|uniprotkb:DLC2(gene name synonym)|uniprotkb:8 kDa dynein light chain b(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836977|imex:IM-21659-62 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000146463(gene)|ensembl:ENST00000314607(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022604"(regulation of cell morphogenesis)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR021893|refseq:XP_016858292.1|refseq:XP_016858293.1|refseq:XP_011540725.1|refseq:XP_011540727.1|refseq:NP_005086.2|ensembl:ENSP00000322915|refseq:XP_005271388.1|uniprotkb:Q5VZL5(identity)|entrezgene/locuslink:9202(identity)|ddbj/embl/genbank:BC127113(identity) go:"GO:0005813"(centrosome)|refseq:NP_542408.1|ensembl:ENSG00000264364(gene)|ensembl:ENST00000579991(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007017"(microtubule-based process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030286"(dynein complex)|go:"GO:0031475"(myosin V complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:Q96FJ2|rcsb pdb:2XQQ|rcsb pdb:3P8M|rcsb pdb:4D07|reactome:R-HSA-139910|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|uniprotkb:Q96FJ2(identity)|entrezgene/locuslink:140735(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:jc8YwR+37J3uD08cXiUnOA2hHEI9606 rogid:4RFpJF40RBja5mOvt/aCv3miiDU9606 intact-crc:D219E4A3690F9DAD|rigid:H99XHcRZJxW2nT2uP8NyQLsEZZQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VZL5 uniprotkb:P62304 intact:EBI-2514659|intact:EBI-28984130|ensembl:ENSP00000322915|uniprotkb:A0JP19|uniprotkb:O43308|uniprotkb:A0JP20|uniprotkb:Q5T5E2|uniprotkb:Q7L3Q4|uniprotkb:Q5T5E1|intact:EBI-2556245 intact:EBI-348082|ensembl:ENSP00000400591|uniprotkb:P08578|uniprotkb:Q15498|uniprotkb:Q5BKT2|uniprotkb:B2R5B9 psi-mi:zmym4_human(display_long)|uniprotkb:ZMYM4(gene name)|psi-mi:ZMYM4(display_short)|uniprotkb:KIAA0425(gene name synonym)|uniprotkb:ZNF262(gene name synonym)|uniprotkb:Zinc finger protein 262(gene name synonym) psi-mi:ruxe_human(display_long)|uniprotkb:SNRPE(gene name)|psi-mi:SNRPE(display_short)|uniprotkb:Sm protein E(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836977|imex:IM-21659-62 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000146463(gene)|ensembl:ENST00000314607(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022604"(regulation of cell morphogenesis)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR021893|refseq:XP_016858292.1|refseq:XP_016858293.1|refseq:XP_011540725.1|refseq:XP_011540727.1|refseq:NP_005086.2|ensembl:ENSP00000322915|refseq:XP_005271388.1|uniprotkb:Q5VZL5(identity)|entrezgene/locuslink:9202(identity)|ddbj/embl/genbank:BC127113(identity) ensembl:ENSG00000182004(gene)|ensembl:ENST00000414487(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0042633"(hair cycle)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027078|mint:P62304|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|refseq:NP_003085.1|refseq:NP_001291393.1|refseq:NP_001315566.1|refseq:NP_001315567.1|dip:DIP-31220N|uniprotkb:P62304(identity)|entrezgene/locuslink:6635(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:jc8YwR+37J3uD08cXiUnOA2hHEI9606 rogid:QZ2/v8M+4+8AfWLPYNQO81/IeN09606 intact-crc:D219E4A3690F9DAD|rigid:H99XHcRZJxW2nT2uP8NyQLsEZZQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VZL5 uniprotkb:Q86XI8 intact:EBI-2514659|intact:EBI-28984130|ensembl:ENSP00000322915|uniprotkb:A0JP19|uniprotkb:O43308|uniprotkb:A0JP20|uniprotkb:Q5T5E2|uniprotkb:Q7L3Q4|uniprotkb:Q5T5E1|intact:EBI-2556245 intact:EBI-2682158|ensembl:ENSP00000331363|uniprotkb:A0A087WWL5 psi-mi:zmym4_human(display_long)|uniprotkb:ZMYM4(gene name)|psi-mi:ZMYM4(display_short)|uniprotkb:KIAA0425(gene name synonym)|uniprotkb:ZNF262(gene name synonym)|uniprotkb:Zinc finger protein 262(gene name synonym) psi-mi:zswm9_human(display_long)|uniprotkb:ZSWIM9(gene name)|psi-mi:ZSWIM9(display_short)|uniprotkb:C19orf68(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836977|imex:IM-21659-62 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000146463(gene)|ensembl:ENST00000314607(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022604"(regulation of cell morphogenesis)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR021893|refseq:XP_016858292.1|refseq:XP_016858293.1|refseq:XP_011540725.1|refseq:XP_011540727.1|refseq:NP_005086.2|ensembl:ENSP00000322915|refseq:XP_005271388.1|uniprotkb:Q5VZL5(identity)|entrezgene/locuslink:9202(identity)|ddbj/embl/genbank:BC127113(identity) refseq:NP_955373.3|ensembl:ENSG00000185453(gene)|ensembl:ENST00000328759(transcript)|interpro:IPR040854|mint:Q86XI8|refseq:XP_006723268.1|uniprotkb:Q86XI8(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:jc8YwR+37J3uD08cXiUnOA2hHEI9606 rogid:4wOy3iLGFg7lgvbA8nWPUgIgS0w9606 intact-crc:D219E4A3690F9DAD|rigid:H99XHcRZJxW2nT2uP8NyQLsEZZQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VZL5 uniprotkb:Q9BUG6 intact:EBI-2514659|intact:EBI-28984130|ensembl:ENSP00000322915|uniprotkb:A0JP19|uniprotkb:O43308|uniprotkb:A0JP20|uniprotkb:Q5T5E2|uniprotkb:Q7L3Q4|uniprotkb:Q5T5E1|intact:EBI-2556245 intact:EBI-8836980|uniprotkb:B4DX98|uniprotkb:Q49A73|uniprotkb:Q53F04|uniprotkb:Q8N7B3|ensembl:ENSP00000375593|ensembl:ENSP00000467631|ensembl:ENSP00000507065 psi-mi:zmym4_human(display_long)|uniprotkb:ZMYM4(gene name)|psi-mi:ZMYM4(display_short)|uniprotkb:KIAA0425(gene name synonym)|uniprotkb:ZNF262(gene name synonym)|uniprotkb:Zinc finger protein 262(gene name synonym) psi-mi:zsa5a_human(display_long)|uniprotkb:ZNF495(gene name synonym)|uniprotkb:ZSCAN5(gene name synonym)|uniprotkb:Zinc finger protein 495(gene name synonym)|uniprotkb:ZSCAN5A(gene name)|psi-mi:ZSCAN5A(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836977|imex:IM-21659-62 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000146463(gene)|ensembl:ENST00000314607(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022604"(regulation of cell morphogenesis)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR021893|refseq:XP_016858292.1|refseq:XP_016858293.1|refseq:XP_011540725.1|refseq:XP_011540727.1|refseq:NP_005086.2|ensembl:ENSP00000322915|refseq:XP_005271388.1|uniprotkb:Q5VZL5(identity)|entrezgene/locuslink:9202(identity)|ddbj/embl/genbank:BC127113(identity) refseq:NP_001308996.1|refseq:NP_001308997.1|refseq:NP_001308998.1|refseq:NP_001308999.1|refseq:NP_001309001.1|refseq:NP_001309002.1|refseq:NP_001309003.1|refseq:NP_001309005.1|refseq:NP_001309006.1|refseq:NP_001309007.1|refseq:NP_001308991.1|refseq:NP_001308993.1|refseq:NP_001308994.1|refseq:NP_001308995.1|refseq:NP_001309004.1|refseq:NP_077279.1|ensembl:ENSG00000131848(gene)|ensembl:ENST00000391713(transcript)|ensembl:ENST00000587340(transcript)|ensembl:ENST00000683990(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR036236|interpro:IPR038269|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001308990.1|refseq:XP_016882788.1|uniprotkb:Q9BUG6(identity)|entrezgene/locuslink:79149(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:jc8YwR+37J3uD08cXiUnOA2hHEI9606 rogid:czD2vEo/sN2hVukG1WNz8EA0XzA9606 intact-crc:D219E4A3690F9DAD|rigid:H99XHcRZJxW2nT2uP8NyQLsEZZQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VZL5 uniprotkb:O60341 intact:EBI-2514659|intact:EBI-28984130|ensembl:ENSP00000322915|uniprotkb:A0JP19|uniprotkb:O43308|uniprotkb:A0JP20|uniprotkb:Q5T5E2|uniprotkb:Q7L3Q4|uniprotkb:Q5T5E1|intact:EBI-2556245 intact:EBI-710124|uniprotkb:Q5TH94|uniprotkb:Q5TH95|uniprotkb:Q86VT7|uniprotkb:Q8IXK4|uniprotkb:Q8NDP6|uniprotkb:Q8TAZ3|uniprotkb:Q96AW4|ensembl:ENSP00000349049|uniprotkb:A8MWP9 psi-mi:zmym4_human(display_long)|uniprotkb:ZMYM4(gene name)|psi-mi:ZMYM4(display_short)|uniprotkb:KIAA0425(gene name synonym)|uniprotkb:ZNF262(gene name synonym)|uniprotkb:Zinc finger protein 262(gene name synonym) psi-mi:kdm1a_human(display_long)|uniprotkb:Flavin-containing amine oxidase domain-containing protein 2(gene name synonym)|uniprotkb:BRAF35-HDAC complex protein BHC110(gene name synonym)|uniprotkb:KDM1A(gene name)|psi-mi:KDM1A(display_short)|uniprotkb:KIAA0601(gene name synonym)|uniprotkb:LSD1(gene name synonym)|uniprotkb:AOF2(gene name synonym)|uniprotkb:KDM1(gene name synonym)|uniprotkb:"[histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A"(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836977|imex:IM-21659-62 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000146463(gene)|ensembl:ENST00000314607(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022604"(regulation of cell morphogenesis)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR021893|refseq:XP_016858292.1|refseq:XP_016858293.1|refseq:XP_011540725.1|refseq:XP_011540727.1|refseq:NP_005086.2|ensembl:ENSP00000322915|refseq:XP_005271388.1|uniprotkb:Q5VZL5(identity)|entrezgene/locuslink:9202(identity)|ddbj/embl/genbank:BC127113(identity) go:"GO:0021987"(cerebral cortex development)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032451"(demethylase activity)|refseq:NP_001009999.1|refseq:NP_055828.2|ensembl:ENSG00000004487(gene)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|ensembl:ENST00000356634(transcript)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-34641N|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0033184"(positive regulation of histone ubiquitination)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042551"(neuron maturation)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043426"(MRF binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046098"(guanine metabolic process)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0060992"(response to fungicide)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061752"(telomeric repeat-containing RNA binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1903827"|go:"GO:1990391"(DNA repair complex)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000648"(positive regulation of stem cell proliferation)|interpro:IPR002937(Amine oxidase)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017366(Histone lysine-specific demethylase)|interpro:IPR036188|interpro:IPR036388|mint:O60341|rcsb pdb:2COM|rcsb pdb:2DW4|rcsb pdb:2EJR|rcsb pdb:2H94|rcsb pdb:2HKO|rcsb pdb:2IW5|rcsb pdb:2L3D|rcsb pdb:2UXN|rcsb pdb:2UXX|rcsb pdb:2V1D|rcsb pdb:2X0L|rcsb pdb:2XAF|rcsb pdb:2XAG|rcsb pdb:2XAH|rcsb pdb:2XAJ|rcsb pdb:2XAQ|rcsb pdb:2XAS|rcsb pdb:2Y48|rcsb pdb:2Z3Y|rcsb pdb:2Z5U|rcsb pdb:3ABT|rcsb pdb:3ABU|rcsb pdb:3ZMS|rcsb pdb:3ZMT|rcsb pdb:3ZMU|rcsb pdb:3ZMV|rcsb pdb:3ZMZ|rcsb pdb:3ZN0|rcsb pdb:3ZN1|rcsb pdb:4BAY|rcsb pdb:4CZZ|rcsb pdb:4KUM|rcsb pdb:4UV8|rcsb pdb:4UV9|rcsb pdb:4UVA|rcsb pdb:4UVB|rcsb pdb:4UVC|rcsb pdb:4UXN|rcsb pdb:4XBF|rcsb pdb:5AFW|rcsb pdb:5H6Q|rcsb pdb:5H6R|rcsb pdb:5IT3|rcsb pdb:5L3B|rcsb pdb:5L3C|rcsb pdb:5L3D|rcsb pdb:5L3E|rcsb pdb:5L3F|rcsb pdb:5L3G|rcsb pdb:5LBQ|rcsb pdb:5LGN|rcsb pdb:5LGT|rcsb pdb:5LGU|rcsb pdb:5LHG|rcsb pdb:5LHH|rcsb pdb:5LHI|rcsb pdb:5X60|rcsb pdb:5YJB|rcsb pdb:6E1F|rcsb pdb:6K3E|rcsb pdb:6KGK|rcsb pdb:6KGL|rcsb pdb:6KGM|rcsb pdb:6KGN|rcsb pdb:6KGO|rcsb pdb:6KGP|rcsb pdb:6KGQ|rcsb pdb:6KGR|rcsb pdb:6NQM|rcsb pdb:6NQU|rcsb pdb:6NR5|rcsb pdb:6S35|rcsb pdb:6TE1|rcsb pdb:6VYP|rcsb pdb:6W4K|rcsb pdb:6WC6|rcsb pdb:7CDC|rcsb pdb:7CDD|rcsb pdb:7CDE|rcsb pdb:7CDF|rcsb pdb:7CDG|rcsb pdb:7E0G|rcsb pdb:7JJL|rcsb pdb:7JJM|rcsb pdb:7JK7|reactome:R-HSA-3214815|reactome:R-HSA-3214842|reactome:R-HSA-5625886|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9679191|reactome:R-HSA-983231|uniprotkb:O60341(identity)|entrezgene/locuslink:23028(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:jc8YwR+37J3uD08cXiUnOA2hHEI9606 rogid:rS9F23Rg1Ha6XOQSisWQfhKVFfs9606 intact-crc:D219E4A3690F9DAD|rigid:H99XHcRZJxW2nT2uP8NyQLsEZZQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VZL5 uniprotkb:A1L0T0 intact:EBI-2514659|intact:EBI-28984130|ensembl:ENSP00000322915|uniprotkb:A0JP19|uniprotkb:O43308|uniprotkb:A0JP20|uniprotkb:Q5T5E2|uniprotkb:Q7L3Q4|uniprotkb:Q5T5E1|intact:EBI-2556245 intact:EBI-720553|uniprotkb:O43341|uniprotkb:Q99651|uniprotkb:Q9BWN5|uniprotkb:Q9UEB2|intact:EBI-3184145|intact:EBI-1236857|uniprotkb:Q96F08|ensembl:ENSP00000263383 psi-mi:zmym4_human(display_long)|uniprotkb:ZMYM4(gene name)|psi-mi:ZMYM4(display_short)|uniprotkb:KIAA0425(gene name synonym)|uniprotkb:ZNF262(gene name synonym)|uniprotkb:Zinc finger protein 262(gene name synonym) psi-mi:hacl2_human(display_long)|uniprotkb:Acetolactate synthase-like protein(gene name synonym)|uniprotkb:HACL2(gene name synonym)|uniprotkb:ILVBL(gene name)|psi-mi:ILVBL(display_short)|uniprotkb:AHAS(gene name synonym)|uniprotkb:IlvB-like protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836977|imex:IM-21659-62 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000146463(gene)|ensembl:ENST00000314607(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022604"(regulation of cell morphogenesis)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR021893|refseq:XP_016858292.1|refseq:XP_016858293.1|refseq:XP_011540725.1|refseq:XP_011540727.1|refseq:NP_005086.2|ensembl:ENSP00000322915|refseq:XP_005271388.1|uniprotkb:Q5VZL5(identity)|entrezgene/locuslink:9202(identity)|ddbj/embl/genbank:BC127113(identity) refseq:NP_006835.2|refseq:XP_005259774.1|ensembl:ENSG00000105135(gene)|ensembl:ENST00000263383(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001561"(fatty acid alpha-oxidation)|go:"GO:0003984"(acetolactate synthase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005948"(acetolactate synthase complex)|go:"GO:0009097"(isoleucine biosynthetic process)|go:"GO:0009099"(valine biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016829"(lyase activity)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR000399(TPP-binding enzymes, conserved site)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR012000(Thiamine pyrophosphate enzyme, central region)|interpro:IPR012001(Thiamine pyrophosphate enzyme, N-terminal TPP binding region)|interpro:IPR029035|interpro:IPR029061|uniprotkb:A1L0T0(identity)|entrezgene/locuslink:10994(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:jc8YwR+37J3uD08cXiUnOA2hHEI9606 rogid:WDj/FsULgscGSIgcTe8+1+vKhS09606 intact-crc:D219E4A3690F9DAD|rigid:H99XHcRZJxW2nT2uP8NyQLsEZZQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VZL5 uniprotkb:Q14839 intact:EBI-2514659|intact:EBI-28984130|ensembl:ENSP00000322915|uniprotkb:A0JP19|uniprotkb:O43308|uniprotkb:A0JP20|uniprotkb:Q5T5E2|uniprotkb:Q7L3Q4|uniprotkb:Q5T5E1|intact:EBI-2556245 intact:EBI-372916|uniprotkb:Q8IXZ5|intact:EBI-28978241|ensembl:ENSP00000440542 psi-mi:zmym4_human(display_long)|uniprotkb:ZMYM4(gene name)|psi-mi:ZMYM4(display_short)|uniprotkb:KIAA0425(gene name synonym)|uniprotkb:ZNF262(gene name synonym)|uniprotkb:Zinc finger protein 262(gene name synonym) psi-mi:chd4_human(display_long)|uniprotkb:CHD4(gene name)|psi-mi:CHD4(display_short)|uniprotkb:ATP-dependent helicase CHD4(gene name synonym)|uniprotkb:Mi-2 autoantigen 218 kDa protein(gene name synonym)|uniprotkb:Mi2-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836977|imex:IM-21659-62 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000146463(gene)|ensembl:ENST00000314607(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022604"(regulation of cell morphogenesis)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR021893|refseq:XP_016858292.1|refseq:XP_016858293.1|refseq:XP_011540725.1|refseq:XP_011540727.1|refseq:NP_005086.2|ensembl:ENSP00000322915|refseq:XP_005271388.1|uniprotkb:Q5VZL5(identity)|entrezgene/locuslink:9202(identity)|ddbj/embl/genbank:BC127113(identity) ensembl:ENSP00000440542|ensembl:ENST00000645095|ensembl:ENSP00000496634|refseq:NP_001264.2|refseq:XP_006719021.1|refseq:NP_001284482.1|ensembl:ENSG00000111642(gene)|ensembl:ENST00000544040(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070615"|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q14839|rcsb pdb:1MM2|rcsb pdb:1MM3|rcsb pdb:2EE1|rcsb pdb:2L5U|rcsb pdb:2L75|rcsb pdb:2N5N|rcsb pdb:4O9I|rcsb pdb:6BGG|rcsb pdb:6Q3M|rcsb pdb:6RYR|rcsb pdb:6RYU|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9031628|reactome:R-HSA-9679191|dip:DIP-31183N|uniprotkb:Q14839(identity)|entrezgene/locuslink:1108(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:jc8YwR+37J3uD08cXiUnOA2hHEI9606 rogid:E9eHT/41SIFRiz54J81hvPQeHIE9606 intact-crc:D219E4A3690F9DAD|rigid:H99XHcRZJxW2nT2uP8NyQLsEZZQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VZL5 uniprotkb:Q9UBW7 intact:EBI-2514659|intact:EBI-28984130|ensembl:ENSP00000322915|uniprotkb:A0JP19|uniprotkb:O43308|uniprotkb:A0JP20|uniprotkb:Q5T5E2|uniprotkb:Q7L3Q4|uniprotkb:Q5T5E1|intact:EBI-2556245 intact:EBI-2797576|uniprotkb:Q5W0T3|uniprotkb:O43434|uniprotkb:O43212|uniprotkb:Q5W0Q4|uniprotkb:Q9UEU2|uniprotkb:Q9H538|uniprotkb:Q9H0V5|uniprotkb:Q8NE39|uniprotkb:Q63HP0|uniprotkb:A6NI02|uniprotkb:A6NDG0|uniprotkb:O60898|ensembl:ENSP00000372324|ensembl:ENSP00000372327|ensembl:ENSP00000479904 psi-mi:zmym4_human(display_long)|uniprotkb:ZMYM4(gene name)|psi-mi:ZMYM4(display_short)|uniprotkb:KIAA0425(gene name synonym)|uniprotkb:ZNF262(gene name synonym)|uniprotkb:Zinc finger protein 262(gene name synonym) psi-mi:zmym2_human(display_long)|uniprotkb:FIM(gene name synonym)|uniprotkb:RAMP(gene name synonym)|uniprotkb:ZNF198(gene name synonym)|uniprotkb:Fused in myeloproliferative disorders protein(gene name synonym)|uniprotkb:Rearranged in atypical myeloproliferative disorder protein(gene name synonym)|uniprotkb:Zinc finger protein 198(gene name synonym)|uniprotkb:ZMYM2(gene name)|psi-mi:ZMYM2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836977|imex:IM-21659-62 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000146463(gene)|ensembl:ENST00000314607(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022604"(regulation of cell morphogenesis)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR021893|refseq:XP_016858292.1|refseq:XP_016858293.1|refseq:XP_011540725.1|refseq:XP_011540727.1|refseq:NP_005086.2|ensembl:ENSP00000322915|refseq:XP_005271388.1|uniprotkb:Q5VZL5(identity)|entrezgene/locuslink:9202(identity)|ddbj/embl/genbank:BC127113(identity) refseq:NP_001177893.1|refseq:NP_001177894.1|refseq:NP_003444.1|refseq:NP_932072.1|ensembl:ENSP00000372324|ensembl:ENSP00000372327|ensembl:ENSP00000479904|refseq:XP_005266577.1|ensembl:ENSG00000121741(gene)|ensembl:ENST00000382871(transcript)|ensembl:ENST00000382874(transcript)|ensembl:ENST00000610343(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR021893|mint:Q9UBW7|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-9703465|refseq:XP_016876218.1|refseq:XP_011533526.1|uniprotkb:Q9UBW7(identity)|entrezgene/locuslink:7750(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:jc8YwR+37J3uD08cXiUnOA2hHEI9606 rogid:rsxYDcDeR5x2Lt3phHNYpCjf9KA9606 intact-crc:D219E4A3690F9DAD|rigid:H99XHcRZJxW2nT2uP8NyQLsEZZQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VZL5 uniprotkb:P78371 intact:EBI-2514659|intact:EBI-28984130|ensembl:ENSP00000322915|uniprotkb:A0JP19|uniprotkb:O43308|uniprotkb:A0JP20|uniprotkb:Q5T5E2|uniprotkb:Q7L3Q4|uniprotkb:Q5T5E1|intact:EBI-2556245 intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300 psi-mi:zmym4_human(display_long)|uniprotkb:ZMYM4(gene name)|psi-mi:ZMYM4(display_short)|uniprotkb:KIAA0425(gene name synonym)|uniprotkb:ZNF262(gene name synonym)|uniprotkb:Zinc finger protein 262(gene name synonym) psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836977|imex:IM-21659-62 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000146463(gene)|ensembl:ENST00000314607(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022604"(regulation of cell morphogenesis)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR021893|refseq:XP_016858292.1|refseq:XP_016858293.1|refseq:XP_011540725.1|refseq:XP_011540727.1|refseq:NP_005086.2|ensembl:ENSP00000322915|refseq:XP_005271388.1|uniprotkb:Q5VZL5(identity)|entrezgene/locuslink:9202(identity)|ddbj/embl/genbank:BC127113(identity) refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695|uniprotkb:P78371(identity)|entrezgene/locuslink:10576(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:jc8YwR+37J3uD08cXiUnOA2hHEI9606 rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606 intact-crc:D219E4A3690F9DAD|rigid:H99XHcRZJxW2nT2uP8NyQLsEZZQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VZL5 uniprotkb:Q9H2P0 intact:EBI-2514659|intact:EBI-28984130|ensembl:ENSP00000322915|uniprotkb:A0JP19|uniprotkb:O43308|uniprotkb:A0JP20|uniprotkb:Q5T5E2|uniprotkb:Q7L3Q4|uniprotkb:Q5T5E1|intact:EBI-2556245 intact:EBI-1764854|uniprotkb:E1P5Y2|uniprotkb:O94881|uniprotkb:Q5BKU2|uniprotkb:Q9UG34|intact:EBI-28975656|ensembl:ENSP00000342905|ensembl:ENSP00000360662|ensembl:ENSP00000379346|ensembl:ENSP00000379349|ensembl:ENSP00000483881 psi-mi:zmym4_human(display_long)|uniprotkb:ZMYM4(gene name)|psi-mi:ZMYM4(display_short)|uniprotkb:KIAA0425(gene name synonym)|uniprotkb:ZNF262(gene name synonym)|uniprotkb:Zinc finger protein 262(gene name synonym) psi-mi:adnp_human(display_long)|uniprotkb:ADNP(gene name)|psi-mi:ADNP(display_short)|uniprotkb:ADNP1(gene name synonym)|uniprotkb:KIAA0784(gene name synonym)|uniprotkb:Activity-dependent neuroprotective protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836977|imex:IM-21659-62 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000146463(gene)|ensembl:ENST00000314607(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022604"(regulation of cell morphogenesis)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR021893|refseq:XP_016858292.1|refseq:XP_016858293.1|refseq:XP_011540725.1|refseq:XP_011540727.1|refseq:NP_005086.2|ensembl:ENSP00000322915|refseq:XP_005271388.1|uniprotkb:Q5VZL5(identity)|entrezgene/locuslink:9202(identity)|ddbj/embl/genbank:BC127113(identity) refseq:NP_001269460.1|refseq:NP_001269461.1|refseq:XP_011527049.1|refseq:NP_056154.1|refseq:NP_852107.1|ensembl:ENSP00000342905|ensembl:ENSP00000360662|ensembl:ENSP00000379346|ensembl:ENSP00000379349|ensembl:ENSP00000483881|ensembl:ENSG00000101126(gene)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0033484"(nitric oxide homeostasis)|ensembl:ENST00000349014(transcript)|ensembl:ENST00000371602(transcript)|ensembl:ENST00000396029(transcript)|ensembl:ENST00000396032(transcript)|ensembl:ENST00000621696(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007614"(short-term memory)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019934"(cGMP-mediated signaling)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042277"(peptide binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044849"(estrous cycle)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR038861|mint:Q9H2P0|refseq:XP_016883247.1|refseq:XP_016883248.1|refseq:NP_001334440.1|dip:DIP-47288N|entrezgene/locuslink:23394(identity)|uniprotkb:Q9H2P0(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:jc8YwR+37J3uD08cXiUnOA2hHEI9606 rogid:QJTl6p2b0Lp7HnHP8sFd5Hv+WGk9606 intact-crc:D219E4A3690F9DAD|rigid:H99XHcRZJxW2nT2uP8NyQLsEZZQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VZL5 uniprotkb:O95218 intact:EBI-2514659|intact:EBI-28984130|ensembl:ENSP00000322915|uniprotkb:A0JP19|uniprotkb:O43308|uniprotkb:A0JP20|uniprotkb:Q5T5E2|uniprotkb:Q7L3Q4|uniprotkb:Q5T5E1|intact:EBI-2556245 intact:EBI-1051583|intact:EBI-1642120|intact:EBI-1163882|intact:EBI-1166395|uniprotkb:Q53GS3|uniprotkb:Q59F92|uniprotkb:Q5VV33|uniprotkb:Q8IXN6|uniprotkb:Q9UP63|uniprotkb:Q5VV34|uniprotkb:D3DQ75|ensembl:ENSP00000359958 psi-mi:zmym4_human(display_long)|uniprotkb:ZMYM4(gene name)|psi-mi:ZMYM4(display_short)|uniprotkb:KIAA0425(gene name synonym)|uniprotkb:ZNF262(gene name synonym)|uniprotkb:Zinc finger protein 262(gene name synonym) psi-mi:zrab2_human(display_long)|uniprotkb:ZRANB2(gene name)|psi-mi:ZRANB2(display_short)|uniprotkb:ZIS(gene name synonym)|uniprotkb:ZNF265(gene name synonym)|uniprotkb:Zinc finger protein 265(gene name synonym)|uniprotkb:Zinc finger, splicing(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836977|imex:IM-21659-62 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000146463(gene)|ensembl:ENST00000314607(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022604"(regulation of cell morphogenesis)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR021893|refseq:XP_016858292.1|refseq:XP_016858293.1|refseq:XP_011540725.1|refseq:XP_011540727.1|refseq:NP_005086.2|ensembl:ENSP00000322915|refseq:XP_005271388.1|uniprotkb:Q5VZL5(identity)|entrezgene/locuslink:9202(identity)|ddbj/embl/genbank:BC127113(identity) refseq:NP_005446.2|refseq:NP_976225.1|ensembl:ENSG00000132485(gene)|ensembl:ENST00000370920(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR017337(Uncharacterised conserved protein UCP037956, zinc finger Ran-binding)|interpro:IPR036443|mint:O95218|rcsb pdb:1N0Z|rcsb pdb:2K1P|rcsb pdb:3G9Y|uniprotkb:O95218(identity)|entrezgene/locuslink:9406(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:jc8YwR+37J3uD08cXiUnOA2hHEI9606 rogid:NSsZyRDwY5bF3I5OGvd1jGYTijY9606 intact-crc:D219E4A3690F9DAD|rigid:H99XHcRZJxW2nT2uP8NyQLsEZZQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VZL5 uniprotkb:Q13263 intact:EBI-2514659|intact:EBI-28984130|ensembl:ENSP00000322915|uniprotkb:A0JP19|uniprotkb:O43308|uniprotkb:A0JP20|uniprotkb:Q5T5E2|uniprotkb:Q7L3Q4|uniprotkb:Q5T5E1|intact:EBI-2556245 intact:EBI-78139|uniprotkb:O00677|ensembl:ENSP00000253024|uniprotkb:Q7Z632|uniprotkb:Q93040|uniprotkb:Q96IM1 psi-mi:zmym4_human(display_long)|uniprotkb:ZMYM4(gene name)|psi-mi:ZMYM4(display_short)|uniprotkb:KIAA0425(gene name synonym)|uniprotkb:ZNF262(gene name synonym)|uniprotkb:Zinc finger protein 262(gene name synonym) psi-mi:tif1b_human(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836977|imex:IM-21659-62 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000146463(gene)|ensembl:ENST00000314607(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022604"(regulation of cell morphogenesis)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR021893|refseq:XP_016858292.1|refseq:XP_016858293.1|refseq:XP_011540725.1|refseq:XP_011540727.1|refseq:NP_005086.2|ensembl:ENSP00000322915|refseq:XP_005271388.1|uniprotkb:Q5VZL5(identity)|entrezgene/locuslink:9202(identity)|ddbj/embl/genbank:BC127113(identity) ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6QAJ|rcsb pdb:6QU1|reactome:R-HSA-212436|reactome:R-HSA-3899300|reactome:R-HSA-9609690|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q13263|rcsb pdb:1FP0|rcsb pdb:2RO1|rcsb pdb:2YVR|rcsb pdb:6H3A|rcsb pdb:6I9H|refseq:NP_005753.1|dip:DIP-30891N|uniprotkb:Q13263(identity)|entrezgene/locuslink:10155(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:jc8YwR+37J3uD08cXiUnOA2hHEI9606 rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606 intact-crc:D219E4A3690F9DAD|rigid:H99XHcRZJxW2nT2uP8NyQLsEZZQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VZL5 uniprotkb:Q9NRR5 intact:EBI-2514659|intact:EBI-28984130|ensembl:ENSP00000322915|uniprotkb:A0JP19|uniprotkb:O43308|uniprotkb:A0JP20|uniprotkb:Q5T5E2|uniprotkb:Q7L3Q4|uniprotkb:Q5T5E1|intact:EBI-2556245 intact:EBI-711226|intact:EBI-722657|uniprotkb:Q9BR98|uniprotkb:Q9UHX4|ensembl:ENSP00000357292|uniprotkb:Q5VYA1|uniprotkb:B2RAY7|uniprotkb:A6ND44|uniprotkb:Q5VYA0 psi-mi:zmym4_human(display_long)|uniprotkb:ZMYM4(gene name)|psi-mi:ZMYM4(display_short)|uniprotkb:KIAA0425(gene name synonym)|uniprotkb:ZNF262(gene name synonym)|uniprotkb:Zinc finger protein 262(gene name synonym) psi-mi:ubql4_human(display_long)|uniprotkb:UBQLN4(gene name)|psi-mi:UBQLN4(display_short)|uniprotkb:C1orf6(gene name synonym)|uniprotkb:UBIN(gene name synonym)|uniprotkb:Ataxin-1 ubiquitin-like-interacting protein A1U(gene name synonym)|uniprotkb:Ataxin-1 interacting ubiquitin-like protein(gene name synonym)|uniprotkb:CIP75(gene name synonym)|uniprotkb:Connexin43-interacting protein of 75 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836977|imex:IM-21659-62 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000146463(gene)|ensembl:ENST00000314607(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022604"(regulation of cell morphogenesis)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR021893|refseq:XP_016858292.1|refseq:XP_016858293.1|refseq:XP_011540725.1|refseq:XP_011540727.1|refseq:NP_005086.2|ensembl:ENSP00000322915|refseq:XP_005271388.1|uniprotkb:Q5VZL5(identity)|entrezgene/locuslink:9202(identity)|ddbj/embl/genbank:BC127113(identity) refseq:NP_001291271.1|refseq:NP_064516.2|ensembl:ENSG00000160803(gene)|interpro:IPR029071|ensembl:ENST00000368309(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090734"(site of DNA damage)|go:"GO:1901097"(negative regulation of autophagosome maturation)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|uniprotkb:Q9NRR5(identity)|entrezgene/locuslink:56893(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:jc8YwR+37J3uD08cXiUnOA2hHEI9606 rogid:H/kLIS8aSMue9jYu1Q4qTcBLt5o9606 intact-crc:D219E4A3690F9DAD|rigid:H99XHcRZJxW2nT2uP8NyQLsEZZQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VZL5 uniprotkb:Q13185 intact:EBI-2514659|intact:EBI-28984130|ensembl:ENSP00000322915|uniprotkb:A0JP19|uniprotkb:O43308|uniprotkb:A0JP20|uniprotkb:Q5T5E2|uniprotkb:Q7L3Q4|uniprotkb:Q5T5E1|intact:EBI-2556245 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:zmym4_human(display_long)|uniprotkb:ZMYM4(gene name)|psi-mi:ZMYM4(display_short)|uniprotkb:KIAA0425(gene name synonym)|uniprotkb:ZNF262(gene name synonym)|uniprotkb:Zinc finger protein 262(gene name synonym) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836977|imex:IM-21659-62 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000146463(gene)|ensembl:ENST00000314607(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022604"(regulation of cell morphogenesis)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR021893|refseq:XP_016858292.1|refseq:XP_016858293.1|refseq:XP_011540725.1|refseq:XP_011540727.1|refseq:NP_005086.2|ensembl:ENSP00000322915|refseq:XP_005271388.1|uniprotkb:Q5VZL5(identity)|entrezgene/locuslink:9202(identity)|ddbj/embl/genbank:BC127113(identity) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:jc8YwR+37J3uD08cXiUnOA2hHEI9606 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 intact-crc:D219E4A3690F9DAD|rigid:H99XHcRZJxW2nT2uP8NyQLsEZZQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VZL5 uniprotkb:P68032 intact:EBI-2514659|intact:EBI-28984130|ensembl:ENSP00000322915|uniprotkb:A0JP19|uniprotkb:O43308|uniprotkb:A0JP20|uniprotkb:Q5T5E2|uniprotkb:Q7L3Q4|uniprotkb:Q5T5E1|intact:EBI-2556245 intact:EBI-352273|uniprotkb:P04270|ensembl:ENSP00000290378 psi-mi:zmym4_human(display_long)|uniprotkb:ZMYM4(gene name)|psi-mi:ZMYM4(display_short)|uniprotkb:KIAA0425(gene name synonym)|uniprotkb:ZNF262(gene name synonym)|uniprotkb:Zinc finger protein 262(gene name synonym) psi-mi:actc_human(display_long)|uniprotkb:ACTC1(gene name)|psi-mi:ACTC1(display_short)|uniprotkb:ACTC(gene name synonym)|uniprotkb:Alpha-cardiac actin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8836977|imex:IM-21659-62 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000146463(gene)|ensembl:ENST00000314607(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022604"(regulation of cell morphogenesis)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR021893|refseq:XP_016858292.1|refseq:XP_016858293.1|refseq:XP_011540725.1|refseq:XP_011540727.1|refseq:NP_005086.2|ensembl:ENSP00000322915|refseq:XP_005271388.1|uniprotkb:Q5VZL5(identity)|entrezgene/locuslink:9202(identity)|ddbj/embl/genbank:BC127113(identity) refseq:NP_005150.1|ensembl:ENSG00000159251(gene)|ensembl:ENST00000290378(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031674"(I band)|go:"GO:0033275"(actin-myosin filament sliding)|go:"GO:0042493"|go:"GO:0044297"(cell body)|go:"GO:0045471"(response to ethanol)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0060047"(heart contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68032|reactome:R-HSA-390522|reactome:R-HSA-8980692|reactome:R-HSA-9013026|uniprotkb:P68032(identity)|entrezgene/locuslink:70(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2017/02/23 rogid:jc8YwR+37J3uD08cXiUnOA2hHEI9606 rogid:U/lKYqWUWMSC3fBHFaAcgzfk+3w9606 intact-crc:D219E4A3690F9DAD|rigid:H99XHcRZJxW2nT2uP8NyQLsEZZQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13398 uniprotkb:Q15773 intact:EBI-1105352|uniprotkb:B9ZVS7|uniprotkb:B4DH10|uniprotkb:B4DLC9|uniprotkb:B4E3C9|uniprotkb:Q05BQ7|uniprotkb:Q2TAL7|uniprotkb:Q59EG4|uniprotkb:Q59G36|uniprotkb:Q5EBL6|uniprotkb:B9ZVW1|uniprotkb:F8WDV2|ensembl:ENSP00000339562 intact:EBI-1051875|intact:EBI-9357094|ensembl:ENSP00000203630|ensembl:ENSP00000403941|ensembl:ENSP00000446317 psi-mi:zn211_human(display_long)|uniprotkb:ZNF211(gene name)|psi-mi:ZNF211(display_short)|uniprotkb:Zinc finger protein C2H2-25(gene name synonym) psi-mi:mlf2_human(display_long)|uniprotkb:Myelodysplasia-myeloid leukemia factor 2(gene name synonym)|uniprotkb:MLF2(gene name)|psi-mi:MLF2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8837070|imex:IM-21659-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001252526.1|refseq:NP_001252527.1|refseq:NP_006376.2|refseq:NP_942152.1|refseq:NP_001252528.1|refseq:NP_001252529.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|ensembl:ENSG00000121417(gene)|ensembl:ENST00000347302(transcript)|uniprotkb:Q13398(identity)|entrezgene/locuslink:10520(identity) refseq:NP_005430.1|ensembl:ENSG00000089693(gene)|ensembl:ENST00000203630(transcript)|ensembl:ENST00000435120(transcript)|ensembl:ENST00000539187(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016020"(membrane)|interpro:IPR019376|mint:Q15773|uniprotkb:Q15773(identity)|entrezgene/locuslink:8079(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:8aTieONHXiZ5MjbGepgD7n0X5hA9606 rogid:Ix7bMALTVwBVty3IAuUn+PP/0BU9606 intact-crc:FEB387BEFB89EB83|rigid:+/NC9MekAVz6oE5vg1GGXDK7SiY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13398 uniprotkb:Q9BQE3 intact:EBI-1105352|uniprotkb:B9ZVS7|uniprotkb:B4DH10|uniprotkb:B4DLC9|uniprotkb:B4E3C9|uniprotkb:Q05BQ7|uniprotkb:Q2TAL7|uniprotkb:Q59EG4|uniprotkb:Q59G36|uniprotkb:Q5EBL6|uniprotkb:B9ZVW1|uniprotkb:F8WDV2|ensembl:ENSP00000339562 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:zn211_human(display_long)|uniprotkb:ZNF211(gene name)|psi-mi:ZNF211(display_short)|uniprotkb:Zinc finger protein C2H2-25(gene name synonym) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8837070|imex:IM-21659-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001252526.1|refseq:NP_001252527.1|refseq:NP_006376.2|refseq:NP_942152.1|refseq:NP_001252528.1|refseq:NP_001252529.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|ensembl:ENSG00000121417(gene)|ensembl:ENST00000347302(transcript)|uniprotkb:Q13398(identity)|entrezgene/locuslink:10520(identity) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1|uniprotkb:Q9BQE3(identity)|entrezgene/locuslink:84790(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:8aTieONHXiZ5MjbGepgD7n0X5hA9606 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:FEB387BEFB89EB83|rigid:+/NC9MekAVz6oE5vg1GGXDK7SiY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13398 uniprotkb:O75190 intact:EBI-1105352|uniprotkb:B9ZVS7|uniprotkb:B4DH10|uniprotkb:B4DLC9|uniprotkb:B4E3C9|uniprotkb:Q05BQ7|uniprotkb:Q2TAL7|uniprotkb:Q59EG4|uniprotkb:Q59G36|uniprotkb:Q5EBL6|uniprotkb:B9ZVW1|uniprotkb:F8WDV2|ensembl:ENSP00000339562 intact:EBI-1053164|uniprotkb:A4D232|uniprotkb:O95806|uniprotkb:A8KAG0|uniprotkb:B4DN73|uniprotkb:E9PCZ2|uniprotkb:Q53EN8|uniprotkb:Q59EF2|uniprotkb:Q6FIC8|uniprotkb:Q75MA2|uniprotkb:Q9UIK6|uniprotkb:A8K7D8|ensembl:ENSP00000262177 psi-mi:zn211_human(display_long)|uniprotkb:ZNF211(gene name)|psi-mi:ZNF211(display_short)|uniprotkb:Zinc finger protein C2H2-25(gene name synonym) psi-mi:dnjb6_human(display_long)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:MSJ-1(gene name synonym)|uniprotkb:HHDJ1(gene name synonym)|uniprotkb:DNAJB6(gene name)|psi-mi:DNAJB6(display_short)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:MSJ1(gene name synonym)|uniprotkb:MRJ(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8837070|imex:IM-21659-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001252526.1|refseq:NP_001252527.1|refseq:NP_006376.2|refseq:NP_942152.1|refseq:NP_001252528.1|refseq:NP_001252529.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|ensembl:ENSG00000121417(gene)|ensembl:ENST00000347302(transcript)|uniprotkb:Q13398(identity)|entrezgene/locuslink:10520(identity) refseq:NP_005485.1|refseq:NP_490647.1|ensembl:ENSG00000105993(gene)|ensembl:ENST00000262177(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0060715"(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:"GO:0060717"(chorion development)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:O75190|rcsb pdb:6U3R|rcsb pdb:6U3S|rcsb pdb:7JSQ|reactome:R-HSA-3371453|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|uniprotkb:O75190(identity)|entrezgene/locuslink:10049(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:8aTieONHXiZ5MjbGepgD7n0X5hA9606 rogid:6X99Uu2SBlHsGCv61ZbwSz4LRp89606 intact-crc:FEB387BEFB89EB83|rigid:+/NC9MekAVz6oE5vg1GGXDK7SiY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13398 uniprotkb:Q13263 intact:EBI-1105352|uniprotkb:B9ZVS7|uniprotkb:B4DH10|uniprotkb:B4DLC9|uniprotkb:B4E3C9|uniprotkb:Q05BQ7|uniprotkb:Q2TAL7|uniprotkb:Q59EG4|uniprotkb:Q59G36|uniprotkb:Q5EBL6|uniprotkb:B9ZVW1|uniprotkb:F8WDV2|ensembl:ENSP00000339562 intact:EBI-78139|uniprotkb:O00677|ensembl:ENSP00000253024|uniprotkb:Q7Z632|uniprotkb:Q93040|uniprotkb:Q96IM1 psi-mi:zn211_human(display_long)|uniprotkb:ZNF211(gene name)|psi-mi:ZNF211(display_short)|uniprotkb:Zinc finger protein C2H2-25(gene name synonym) psi-mi:tif1b_human(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8837070|imex:IM-21659-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001252526.1|refseq:NP_001252527.1|refseq:NP_006376.2|refseq:NP_942152.1|refseq:NP_001252528.1|refseq:NP_001252529.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|ensembl:ENSG00000121417(gene)|ensembl:ENST00000347302(transcript)|uniprotkb:Q13398(identity)|entrezgene/locuslink:10520(identity) ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6QAJ|rcsb pdb:6QU1|reactome:R-HSA-212436|reactome:R-HSA-3899300|reactome:R-HSA-9609690|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q13263|rcsb pdb:1FP0|rcsb pdb:2RO1|rcsb pdb:2YVR|rcsb pdb:6H3A|rcsb pdb:6I9H|refseq:NP_005753.1|dip:DIP-30891N|uniprotkb:Q13263(identity)|entrezgene/locuslink:10155(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:8aTieONHXiZ5MjbGepgD7n0X5hA9606 rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606 intact-crc:FEB387BEFB89EB83|rigid:+/NC9MekAVz6oE5vg1GGXDK7SiY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13398 uniprotkb:A6NFI3 intact:EBI-1105352|uniprotkb:B9ZVS7|uniprotkb:B4DH10|uniprotkb:B4DLC9|uniprotkb:B4E3C9|uniprotkb:Q05BQ7|uniprotkb:Q2TAL7|uniprotkb:Q59EG4|uniprotkb:Q59G36|uniprotkb:Q5EBL6|uniprotkb:B9ZVW1|uniprotkb:F8WDV2|ensembl:ENSP00000339562 intact:EBI-8837065|ensembl:ENSP00000477706 psi-mi:zn211_human(display_long)|uniprotkb:ZNF211(gene name)|psi-mi:ZNF211(display_short)|uniprotkb:Zinc finger protein C2H2-25(gene name synonym) psi-mi:zn316_human(display_long)|uniprotkb:ZNF316(gene name)|psi-mi:ZNF316(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8837070|imex:IM-21659-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001252526.1|refseq:NP_001252527.1|refseq:NP_006376.2|refseq:NP_942152.1|refseq:NP_001252528.1|refseq:NP_001252529.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|ensembl:ENSG00000121417(gene)|ensembl:ENST00000347302(transcript)|uniprotkb:Q13398(identity)|entrezgene/locuslink:10520(identity) refseq:NP_001265488.1|refseq:XP_006715693.1|ensembl:ENSG00000205903(gene)|ensembl:ENST00000382252(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|uniprotkb:A6NFI3(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:8aTieONHXiZ5MjbGepgD7n0X5hA9606 rogid:30kkVY+rcogc0MwvKpOQ5TWC1X89606 intact-crc:FEB387BEFB89EB83|rigid:+/NC9MekAVz6oE5vg1GGXDK7SiY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13398 uniprotkb:Q14592 intact:EBI-1105352|uniprotkb:B9ZVS7|uniprotkb:B4DH10|uniprotkb:B4DLC9|uniprotkb:B4E3C9|uniprotkb:Q05BQ7|uniprotkb:Q2TAL7|uniprotkb:Q59EG4|uniprotkb:Q59G36|uniprotkb:Q5EBL6|uniprotkb:B9ZVW1|uniprotkb:F8WDV2|ensembl:ENSP00000339562 intact:EBI-2555738|uniprotkb:B4DNX9|uniprotkb:A4FU64|uniprotkb:Q2VPC7|uniprotkb:Q6VSF8|ensembl:ENSP00000353491 psi-mi:zn211_human(display_long)|uniprotkb:ZNF211(gene name)|psi-mi:ZNF211(display_short)|uniprotkb:Zinc finger protein C2H2-25(gene name synonym) psi-mi:zn460_human(display_long)|uniprotkb:ZNF272(gene name synonym)|uniprotkb:Zinc finger protein 272(gene name synonym)|uniprotkb:Zinc finger protein HZF8(gene name synonym)|uniprotkb:ZNF460(gene name)|psi-mi:ZNF460(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8837070|imex:IM-21659-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001252526.1|refseq:NP_001252527.1|refseq:NP_006376.2|refseq:NP_942152.1|refseq:NP_001252528.1|refseq:NP_001252529.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|ensembl:ENSG00000121417(gene)|ensembl:ENST00000347302(transcript)|uniprotkb:Q13398(identity)|entrezgene/locuslink:10520(identity) refseq:NP_006626.3|ensembl:ENSG00000197714(gene)|ensembl:ENST00000360338(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|refseq:NP_001317551.1|uniprotkb:Q14592(identity)|entrezgene/locuslink:10794(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:8aTieONHXiZ5MjbGepgD7n0X5hA9606 rogid:MajnrRpwOQccWLawp3dN4rE5J189606 intact-crc:FEB387BEFB89EB83|rigid:+/NC9MekAVz6oE5vg1GGXDK7SiY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13398 uniprotkb:Q9ULX6 intact:EBI-1105352|uniprotkb:B9ZVS7|uniprotkb:B4DH10|uniprotkb:B4DLC9|uniprotkb:B4E3C9|uniprotkb:Q05BQ7|uniprotkb:Q2TAL7|uniprotkb:Q59EG4|uniprotkb:Q59G36|uniprotkb:Q5EBL6|uniprotkb:B9ZVW1|uniprotkb:F8WDV2|ensembl:ENSP00000339562 intact:EBI-357530|uniprotkb:O94792|uniprotkb:Q96J58|uniprotkb:Q9NRQ0|uniprotkb:Q9UGM0|uniprotkb:B5BU90|uniprotkb:B4DJ74|ensembl:ENSP00000380557 psi-mi:zn211_human(display_long)|uniprotkb:ZNF211(gene name)|psi-mi:ZNF211(display_short)|uniprotkb:Zinc finger protein C2H2-25(gene name synonym) psi-mi:akp8l_human(display_long)|uniprotkb:AKAP8L(gene name)|psi-mi:AKAP8L(display_short)|uniprotkb:HRIHFB2018(orf name)|uniprotkb:NAKAP95(gene name synonym)|uniprotkb:Neighbor of A-kinase-anchoring protein 95(gene name synonym)|uniprotkb:Homologous to AKAP95 protein(gene name synonym)|uniprotkb:Helicase A-binding protein 95(gene name synonym)|uniprotkb:NAKAP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8837070|imex:IM-21659-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001252526.1|refseq:NP_001252527.1|refseq:NP_006376.2|refseq:NP_942152.1|refseq:NP_001252528.1|refseq:NP_001252529.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|ensembl:ENSG00000121417(gene)|ensembl:ENST00000347302(transcript)|uniprotkb:Q13398(identity)|entrezgene/locuslink:10520(identity) refseq:NP_001278407.1|refseq:NP_055186.3|dip:DIP-27541N|ensembl:ENSG00000011243(gene)|ensembl:ENST00000397410(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0033127"(regulation of histone phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044839"(cell cycle G2/M phase transition)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007071("A-kinase anchoring protein 95 (AKAP95)")|interpro:IPR034736|mint:Q9ULX6|uniprotkb:Q9ULX6(identity)|entrezgene/locuslink:26993(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:8aTieONHXiZ5MjbGepgD7n0X5hA9606 rogid:SAs8jxuWxLOiWN/TRyjVvr5m/5Y9606 intact-crc:FEB387BEFB89EB83|rigid:+/NC9MekAVz6oE5vg1GGXDK7SiY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13398 uniprotkb:P62891 intact:EBI-1105352|uniprotkb:B9ZVS7|uniprotkb:B4DH10|uniprotkb:B4DLC9|uniprotkb:B4E3C9|uniprotkb:Q05BQ7|uniprotkb:Q2TAL7|uniprotkb:Q59EG4|uniprotkb:Q59G36|uniprotkb:Q5EBL6|uniprotkb:B9ZVW1|uniprotkb:F8WDV2|ensembl:ENSP00000339562 intact:EBI-8830744|uniprotkb:P02404|uniprotkb:Q9BYF2|uniprotkb:P39025|ensembl:ENSP00000355315 psi-mi:zn211_human(display_long)|uniprotkb:ZNF211(gene name)|psi-mi:ZNF211(display_short)|uniprotkb:Zinc finger protein C2H2-25(gene name synonym) psi-mi:rl39_human(display_long)|uniprotkb:RPL39(gene name)|psi-mi:RPL39(display_short)|uniprotkb:Large ribosomal subunit protein eL39(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8837070|imex:IM-21659-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001252526.1|refseq:NP_001252527.1|refseq:NP_006376.2|refseq:NP_942152.1|refseq:NP_001252528.1|refseq:NP_001252529.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|ensembl:ENSG00000121417(gene)|ensembl:ENST00000347302(transcript)|uniprotkb:Q13398(identity)|entrezgene/locuslink:10520(identity) refseq:NP_000991.1|rcsb pdb:4V6X|ensembl:ENSG00000198918(gene)|ensembl:ENST00000361575(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000077(Ribosomal protein L39e)|interpro:IPR020083|interpro:IPR023626|rcsb pdb:4UG0|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|uniprotkb:P62891(identity)|entrezgene/locuslink:6170(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/09/18 rogid:8aTieONHXiZ5MjbGepgD7n0X5hA9606 rogid:AZus2dxwJsTxAOwnJ93E2yhasbo9606 intact-crc:FEB387BEFB89EB83|rigid:+/NC9MekAVz6oE5vg1GGXDK7SiY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JM2 uniprotkb:P45973 intact:EBI-1210359|uniprotkb:Q8N408|uniprotkb:Q5T0T4|intact:EBI-28975500|ensembl:ENSP00000277225 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 psi-mi:zn462_human(display_long)|uniprotkb:ZNF462(gene name)|psi-mi:ZNF462(display_short)|uniprotkb:KIAA1803(gene name synonym)|uniprotkb:Zinc finger PBX1-interacting protein(gene name synonym) psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8837110|imex:IM-21659-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067047.4|ensembl:ENSP00000277225|ensembl:ENST00000441147|ensembl:ENSP00000397306|refseq:XP_006717278.1|refseq:XP_006717279.1|dip:DIP-39340N|ensembl:ENSG00000148143(gene)|ensembl:ENST00000277225(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q96JM2|rcsb pdb:1X6F|uniprotkb:Q96JM2(identity)|ddbj/embl/genbank:BC036884(identity)|entrezgene/locuslink:58499(identity) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|entrezgene/locuslink:23468(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:ftIOu4wVkBWJw+4aHw+R+nN44Vc9606 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 intact-crc:5A83CA767B36471A|rigid:tlrFi0tZ3yDerQu8npNLwFjz07w false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JM2 uniprotkb:Q13263 intact:EBI-1210359|uniprotkb:Q8N408|uniprotkb:Q5T0T4|intact:EBI-28975500|ensembl:ENSP00000277225 intact:EBI-78139|uniprotkb:O00677|ensembl:ENSP00000253024|uniprotkb:Q7Z632|uniprotkb:Q93040|uniprotkb:Q96IM1 psi-mi:zn462_human(display_long)|uniprotkb:ZNF462(gene name)|psi-mi:ZNF462(display_short)|uniprotkb:KIAA1803(gene name synonym)|uniprotkb:Zinc finger PBX1-interacting protein(gene name synonym) psi-mi:tif1b_human(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8837110|imex:IM-21659-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067047.4|ensembl:ENSP00000277225|ensembl:ENST00000441147|ensembl:ENSP00000397306|refseq:XP_006717278.1|refseq:XP_006717279.1|dip:DIP-39340N|ensembl:ENSG00000148143(gene)|ensembl:ENST00000277225(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q96JM2|rcsb pdb:1X6F|uniprotkb:Q96JM2(identity)|ddbj/embl/genbank:BC036884(identity)|entrezgene/locuslink:58499(identity) ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6QAJ|rcsb pdb:6QU1|reactome:R-HSA-212436|reactome:R-HSA-3899300|reactome:R-HSA-9609690|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q13263|rcsb pdb:1FP0|rcsb pdb:2RO1|rcsb pdb:2YVR|rcsb pdb:6H3A|rcsb pdb:6I9H|refseq:NP_005753.1|dip:DIP-30891N|uniprotkb:Q13263(identity)|entrezgene/locuslink:10155(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:ftIOu4wVkBWJw+4aHw+R+nN44Vc9606 rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606 intact-crc:5A83CA767B36471A|rigid:tlrFi0tZ3yDerQu8npNLwFjz07w false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JM2 uniprotkb:Q13185 intact:EBI-1210359|uniprotkb:Q8N408|uniprotkb:Q5T0T4|intact:EBI-28975500|ensembl:ENSP00000277225 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:zn462_human(display_long)|uniprotkb:ZNF462(gene name)|psi-mi:ZNF462(display_short)|uniprotkb:KIAA1803(gene name synonym)|uniprotkb:Zinc finger PBX1-interacting protein(gene name synonym) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8837110|imex:IM-21659-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067047.4|ensembl:ENSP00000277225|ensembl:ENST00000441147|ensembl:ENSP00000397306|refseq:XP_006717278.1|refseq:XP_006717279.1|dip:DIP-39340N|ensembl:ENSG00000148143(gene)|ensembl:ENST00000277225(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q96JM2|rcsb pdb:1X6F|uniprotkb:Q96JM2(identity)|ddbj/embl/genbank:BC036884(identity)|entrezgene/locuslink:58499(identity) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N|uniprotkb:Q13185(identity)|entrezgene/locuslink:11335(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:ftIOu4wVkBWJw+4aHw+R+nN44Vc9606 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 intact-crc:5A83CA767B36471A|rigid:tlrFi0tZ3yDerQu8npNLwFjz07w false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JM2 uniprotkb:O95831 intact:EBI-1210359|uniprotkb:Q8N408|uniprotkb:Q5T0T4|intact:EBI-28975500|ensembl:ENSP00000277225 intact:EBI-356440|uniprotkb:Q5JUZ7|uniprotkb:Q6I9X6|uniprotkb:Q9Y3I3|uniprotkb:Q9Y3I4|uniprotkb:A4QPB4|uniprotkb:B1ALN1|uniprotkb:B2RB08|intact:EBI-2561858|uniprotkb:D3DTE9|uniprotkb:Q1L6K6|uniprotkb:Q2QKE4|uniprotkb:Q1L6K4|ensembl:ENSP00000287295|uniprotkb:E9PRR0 psi-mi:zn462_human(display_long)|uniprotkb:ZNF462(gene name)|psi-mi:ZNF462(display_short)|uniprotkb:KIAA1803(gene name synonym)|uniprotkb:Zinc finger PBX1-interacting protein(gene name synonym) psi-mi:aifm1_human(display_long)|uniprotkb:AIFM1(gene name)|psi-mi:AIFM1(display_short)|uniprotkb:AIF(gene name synonym)|uniprotkb:PDCD8(gene name synonym)|uniprotkb:Programmed cell death protein 8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8837110|imex:IM-21659-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067047.4|ensembl:ENSP00000277225|ensembl:ENST00000441147|ensembl:ENSP00000397306|refseq:XP_006717278.1|refseq:XP_006717279.1|dip:DIP-39340N|ensembl:ENSG00000148143(gene)|ensembl:ENST00000277225(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q96JM2|rcsb pdb:1X6F|uniprotkb:Q96JM2(identity)|ddbj/embl/genbank:BC036884(identity)|entrezgene/locuslink:58499(identity) refseq:NP_001124319.1|refseq:NP_004199.1|refseq:NP_665811.1|refseq:NP_001124318.2|rcsb pdb:5FS6|rcsb pdb:5FS7|rcsb pdb:5FS8|rcsb pdb:5FS9|rcsb pdb:5KVH|rcsb pdb:5KVI|ensembl:ENSG00000156709(gene)|ensembl:ENST00000287295(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016651"("oxidoreductase activity, acting on NAD(P)H")|go:"GO:0030182"(neuron differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0071949"(FAD binding)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902510"(regulation of apoptotic DNA fragmentation)|go:"GO:1904045"(cellular response to aldosterone)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR029324|interpro:IPR036188|mint:O95831|rcsb pdb:1M6I|rcsb pdb:4BUR|rcsb pdb:4BV6|rcsb pdb:4FDC|rcsb pdb:4LII|rcsb pdb:5FMH|dip:DIP-32975N|uniprotkb:O95831(identity)|entrezgene/locuslink:9131(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:ftIOu4wVkBWJw+4aHw+R+nN44Vc9606 rogid:tAY+mPStfDGbCN4OpvHF4ljQ69I9606 intact-crc:5A83CA767B36471A|rigid:tlrFi0tZ3yDerQu8npNLwFjz07w false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JM2 uniprotkb:P83916 intact:EBI-1210359|uniprotkb:Q8N408|uniprotkb:Q5T0T4|intact:EBI-28975500|ensembl:ENSP00000277225 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 psi-mi:zn462_human(display_long)|uniprotkb:ZNF462(gene name)|psi-mi:ZNF462(display_short)|uniprotkb:KIAA1803(gene name synonym)|uniprotkb:Zinc finger PBX1-interacting protein(gene name synonym) psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8837110|imex:IM-21659-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067047.4|ensembl:ENSP00000277225|ensembl:ENST00000441147|ensembl:ENSP00000397306|refseq:XP_006717278.1|refseq:XP_006717279.1|dip:DIP-39340N|ensembl:ENSG00000148143(gene)|ensembl:ENST00000277225(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q96JM2|rcsb pdb:1X6F|uniprotkb:Q96JM2(identity)|ddbj/embl/genbank:BC036884(identity)|entrezgene/locuslink:58499(identity) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N|uniprotkb:P83916(identity)|entrezgene/locuslink:10951(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:ftIOu4wVkBWJw+4aHw+R+nN44Vc9606 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 intact-crc:5A83CA767B36471A|rigid:tlrFi0tZ3yDerQu8npNLwFjz07w false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JM2 uniprotkb:Q9UJP4 intact:EBI-1210359|uniprotkb:Q8N408|uniprotkb:Q5T0T4|intact:EBI-28975500|ensembl:ENSP00000277225 intact:EBI-8837113|uniprotkb:Q8N4I6|uniprotkb:Q5SY28|uniprotkb:O75057|uniprotkb:Q5SY26|uniprotkb:Q8NF10|uniprotkb:B3KQP2|ensembl:ENSP00000366886 psi-mi:zn462_human(display_long)|uniprotkb:ZNF462(gene name)|psi-mi:ZNF462(display_short)|uniprotkb:KIAA1803(gene name synonym)|uniprotkb:Zinc finger PBX1-interacting protein(gene name synonym) psi-mi:klh21_human(display_long)|uniprotkb:KIAA0469(gene name synonym)|uniprotkb:KLHL21(gene name)|psi-mi:KLHL21(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8837110|imex:IM-21659-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067047.4|ensembl:ENSP00000277225|ensembl:ENST00000441147|ensembl:ENSP00000397306|refseq:XP_006717278.1|refseq:XP_006717279.1|dip:DIP-39340N|ensembl:ENSG00000148143(gene)|ensembl:ENST00000277225(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q96JM2|rcsb pdb:1X6F|uniprotkb:Q96JM2(identity)|ddbj/embl/genbank:BC036884(identity)|entrezgene/locuslink:58499(identity) refseq:NP_055666.2|ensembl:ENSG00000162413(gene)|ensembl:ENST00000377658(transcript)|go:"GO:0005827"(polar microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035853"(chromosome passenger complex localization to spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030577|reactome:R-HSA-8951664|reactome:R-HSA-983168|uniprotkb:Q9UJP4(identity)|entrezgene/locuslink:9903(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:ftIOu4wVkBWJw+4aHw+R+nN44Vc9606 rogid:u/kx6rw2ps3q3SG+CaqBs3PbOUg9606 intact-crc:5A83CA767B36471A|rigid:tlrFi0tZ3yDerQu8npNLwFjz07w false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JM2 uniprotkb:Q9H9B1 intact:EBI-1210359|uniprotkb:Q8N408|uniprotkb:Q5T0T4|intact:EBI-28975500|ensembl:ENSP00000277225 intact:EBI-766087|uniprotkb:Q8TCN7|uniprotkb:Q96F53|uniprotkb:Q96JF1|uniprotkb:Q96KH4|uniprotkb:B1AQ58|uniprotkb:B1AQ59|uniprotkb:Q86X08|ensembl:ENSP00000417980 psi-mi:zn462_human(display_long)|uniprotkb:ZNF462(gene name)|psi-mi:ZNF462(display_short)|uniprotkb:KIAA1803(gene name synonym)|uniprotkb:Zinc finger PBX1-interacting protein(gene name synonym) psi-mi:ehmt1_human(display_long)|uniprotkb:KMT1D(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 5(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 1(gene name synonym)|uniprotkb:G9a-like protein 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1D(gene name synonym)|uniprotkb:EHMT1(gene name)|psi-mi:EHMT1(display_short)|uniprotkb:EUHMTASE1(gene name synonym)|uniprotkb:KIAA1876(gene name synonym)|uniprotkb:GLP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8837110|imex:IM-21659-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067047.4|ensembl:ENSP00000277225|ensembl:ENST00000441147|ensembl:ENSP00000397306|refseq:XP_006717278.1|refseq:XP_006717279.1|dip:DIP-39340N|ensembl:ENSG00000148143(gene)|ensembl:ENST00000277225(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q96JM2|rcsb pdb:1X6F|uniprotkb:Q96JM2(identity)|ddbj/embl/genbank:BC036884(identity)|entrezgene/locuslink:58499(identity) refseq:NP_001138999.1|refseq:NP_079033.4|ensembl:ENST00000371394|ensembl:ENSP00000485945|ensembl:ENSP00000417980|ensembl:ENST00000462484|ensembl:ENSP00000417328|dip:DIP-34585N|ensembl:ENSG00000181090(gene)|ensembl:ENST00000460843(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016604"(nuclear body)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038035|interpro:IPR043550|mint:Q9H9B1|rcsb pdb:2IGQ|rcsb pdb:2RFI|rcsb pdb:3B7B|rcsb pdb:3B95|rcsb pdb:3FPD|rcsb pdb:3HNA|rcsb pdb:3MO0|rcsb pdb:3MO2|rcsb pdb:3MO5|rcsb pdb:3SW9|rcsb pdb:3SWC|rcsb pdb:4I51|rcsb pdb:5TTG|rcsb pdb:5TUZ|rcsb pdb:5V9J|rcsb pdb:5VSD|rcsb pdb:5VSF|rcsb pdb:6BY9|rcsb pdb:6MBO|rcsb pdb:6MBP|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-6804760|reactome:R-HSA-8853884|reactome:R-HSA-8953750|uniprotkb:Q9H9B1(identity)|entrezgene/locuslink:79813(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:ftIOu4wVkBWJw+4aHw+R+nN44Vc9606 rogid:4L6QOGSsRPi8hDjS2/BYShjpnf89606 intact-crc:5A83CA767B36471A|rigid:tlrFi0tZ3yDerQu8npNLwFjz07w false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JM2 uniprotkb:Q9Y230 intact:EBI-1210359|uniprotkb:Q8N408|uniprotkb:Q5T0T4|intact:EBI-28975500|ensembl:ENSP00000277225 intact:EBI-352939|ensembl:ENSP00000473172|uniprotkb:Q6FIB9|uniprotkb:Q6PK27|uniprotkb:Q9Y361|uniprotkb:B3KQ59|uniprotkb:E7ETE5|intact:EBI-1058527 psi-mi:zn462_human(display_long)|uniprotkb:ZNF462(gene name)|psi-mi:ZNF462(display_short)|uniprotkb:KIAA1803(gene name synonym)|uniprotkb:Zinc finger PBX1-interacting protein(gene name synonym) psi-mi:ruvb2_human(display_long)|uniprotkb:RUVBL2(gene name)|psi-mi:RUVBL2(display_short)|uniprotkb:TIP48(gene name synonym)|uniprotkb:TIP49B(gene name synonym)|uniprotkb:CGI-46(orf name)|uniprotkb:48 kDa TATA box-binding protein-interacting protein(gene name synonym)|uniprotkb:TIP49b(gene name synonym)|uniprotkb:Repressing pontin 52(gene name synonym)|uniprotkb:51 kDa erythrocyte cytosolic protein(gene name synonym)|uniprotkb:INO80J(gene name synonym)|uniprotkb:TIP60-associated protein 54-beta(gene name synonym)|uniprotkb:INO80 complex subunit J(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8837110|imex:IM-21659-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067047.4|ensembl:ENSP00000277225|ensembl:ENST00000441147|ensembl:ENSP00000397306|refseq:XP_006717278.1|refseq:XP_006717279.1|dip:DIP-39340N|ensembl:ENSG00000148143(gene)|ensembl:ENST00000277225(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q96JM2|rcsb pdb:1X6F|uniprotkb:Q96JM2(identity)|ddbj/embl/genbank:BC036884(identity)|entrezgene/locuslink:58499(identity) go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037942|interpro:IPR041048|interpro:IPR042487|mint:Q9Y230|rcsb pdb:2CQA|rcsb pdb:2XSZ|rcsb pdb:3UK6|rcsb pdb:5OAF|rcsb pdb:6FO1|rcsb pdb:6H7X|rcsb pdb:6HTS|rcsb pdb:6IGM|rcsb pdb:6K0R|rcsb pdb:6QI8|rcsb pdb:6QI9|rcsb pdb:7AHO|reactome:R-HSA-171319|go:"GO:0140585"(promoter-enhancer loop anchoring activity)|reactome:R-HSA-3214847|ensembl:ENSG00000183207(gene)|ensembl:ENST00000595090(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000791"(euchromatin)|go:"GO:0000812"(Swr1 complex)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006457"(protein folding)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0016573"(histone acetylation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|refseq:NP_006657.1|refseq:XP_011524632.1|refseq:NP_001308120.1|dip:DIP-28153N|uniprotkb:Q9Y230(identity)|entrezgene/locuslink:10856(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:ftIOu4wVkBWJw+4aHw+R+nN44Vc9606 rogid:APKAWLDCJVULUP3nzqIaSLHKVN49606 intact-crc:5A83CA767B36471A|rigid:tlrFi0tZ3yDerQu8npNLwFjz07w false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JM2 uniprotkb:Q8N465 intact:EBI-1210359|uniprotkb:Q8N408|uniprotkb:Q5T0T4|intact:EBI-28975500|ensembl:ENSP00000277225 intact:EBI-1053783|uniprotkb:Q6IQ24|uniprotkb:Q8N5Q8|uniprotkb:B4E3L6|uniprotkb:E7ENP2|ensembl:ENSP00000315351 psi-mi:zn462_human(display_long)|uniprotkb:ZNF462(gene name)|psi-mi:ZNF462(display_short)|uniprotkb:KIAA1803(gene name synonym)|uniprotkb:Zinc finger PBX1-interacting protein(gene name synonym) psi-mi:d2hdh_human(display_long)|uniprotkb:D2HGDH(gene name)|psi-mi:D2HGDH(display_short)|uniprotkb:D2HGD(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8837110|imex:IM-21659-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067047.4|ensembl:ENSP00000277225|ensembl:ENST00000441147|ensembl:ENSP00000397306|refseq:XP_006717278.1|refseq:XP_006717279.1|dip:DIP-39340N|ensembl:ENSG00000148143(gene)|ensembl:ENST00000277225(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q96JM2|rcsb pdb:1X6F|uniprotkb:Q96JM2(identity)|ddbj/embl/genbank:BC036884(identity)|entrezgene/locuslink:58499(identity) refseq:NP_001274178.1|refseq:NP_689996.4|refseq:XP_011510062.1|ensembl:ENSG00000180902(gene)|ensembl:ENST00000321264(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006108"(malate metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010042"(response to manganese ion)|go:"GO:0010043"(response to zinc ion)|go:"GO:0032025"(response to cobalt ion)|go:"GO:0044267"(cellular protein metabolic process)|go:"GO:0051990"("(R)-2-hydroxyglutarate dehydrogenase activity")|go:"GO:0071949"(FAD binding)|interpro:IPR004113(FAD-linked oxidase, C-terminal)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR016164(FAD-linked oxidase-like, C-terminal)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR016171(Vanillyl-alcohol oxidase, C-terminal subdomain 2)|interpro:IPR036318|rcsb pdb:6LPN|rcsb pdb:6LPP|rcsb pdb:6LPQ|rcsb pdb:6LPT|rcsb pdb:6LPU|rcsb pdb:6LPX|reactome:R-HSA-880009|uniprotkb:Q8N465(identity)|entrezgene/locuslink:728294(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:ftIOu4wVkBWJw+4aHw+R+nN44Vc9606 rogid:R8UD9gbt3+1MYgPU82yGk6V95Rs9606 intact-crc:5A83CA767B36471A|rigid:tlrFi0tZ3yDerQu8npNLwFjz07w false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JM2 uniprotkb:Q14257 intact:EBI-1210359|uniprotkb:Q8N408|uniprotkb:Q5T0T4|intact:EBI-28975500|ensembl:ENSP00000277225 intact:EBI-356710|uniprotkb:A8MTG6|uniprotkb:Q53XN8|ensembl:ENSP00000378349|uniprotkb:F8WCY5 psi-mi:zn462_human(display_long)|uniprotkb:ZNF462(gene name)|psi-mi:ZNF462(display_short)|uniprotkb:KIAA1803(gene name synonym)|uniprotkb:Zinc finger PBX1-interacting protein(gene name synonym) psi-mi:rcn2_human(display_long)|uniprotkb:RCN2(gene name)|psi-mi:RCN2(display_short)|uniprotkb:ERC55(gene name synonym)|uniprotkb:Calcium-binding protein ERC-55(gene name synonym)|uniprotkb:E6-binding protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8837110|imex:IM-21659-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067047.4|ensembl:ENSP00000277225|ensembl:ENST00000441147|ensembl:ENSP00000397306|refseq:XP_006717278.1|refseq:XP_006717279.1|dip:DIP-39340N|ensembl:ENSG00000148143(gene)|ensembl:ENST00000277225(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q96JM2|rcsb pdb:1X6F|uniprotkb:Q96JM2(identity)|ddbj/embl/genbank:BC036884(identity)|entrezgene/locuslink:58499(identity) refseq:NP_002893.1|ensembl:ENST00000394885(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|ensembl:ENSG00000117906(gene)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q14257|refseq:NP_001258766.1|uniprotkb:Q14257(identity)|entrezgene/locuslink:5955(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:ftIOu4wVkBWJw+4aHw+R+nN44Vc9606 rogid:99ru/7eYUvZ5xdb+x4inbib3PP89606 intact-crc:5A83CA767B36471A|rigid:tlrFi0tZ3yDerQu8npNLwFjz07w false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JM2 uniprotkb:O95785 intact:EBI-1210359|uniprotkb:Q8N408|uniprotkb:Q5T0T4|intact:EBI-28975500|ensembl:ENSP00000277225 intact:EBI-1387294|uniprotkb:B7ZM82|uniprotkb:Q4G0E0|uniprotkb:Q6P6B0|uniprotkb:Q6ZN24|uniprotkb:Q7LDY6|uniprotkb:Q7LDZ1|uniprotkb:Q96IG5|uniprotkb:Q96SQ6|uniprotkb:Q9BUR8|uniprotkb:Q9NPT1|intact:EBI-10967552|uniprotkb:B3KVH1|uniprotkb:M0QY21 psi-mi:zn462_human(display_long)|uniprotkb:ZNF462(gene name)|psi-mi:ZNF462(display_short)|uniprotkb:KIAA1803(gene name synonym)|uniprotkb:Zinc finger PBX1-interacting protein(gene name synonym) psi-mi:wiz_human(display_long)|uniprotkb:WIZ(gene name)|psi-mi:WIZ(display_short)|uniprotkb:ZNF803(gene name synonym)|uniprotkb:Widely-interspaced zinc finger-containing protein(gene name synonym)|uniprotkb:Zinc finger protein 803(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8837110|imex:IM-21659-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067047.4|ensembl:ENSP00000277225|ensembl:ENST00000441147|ensembl:ENSP00000397306|refseq:XP_006717278.1|refseq:XP_006717279.1|dip:DIP-39340N|ensembl:ENSG00000148143(gene)|ensembl:ENST00000277225(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q96JM2|rcsb pdb:1X6F|uniprotkb:Q96JM2(identity)|ddbj/embl/genbank:BC036884(identity)|entrezgene/locuslink:58499(identity) refseq:NP_067064.2|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001317324.1|interpro:IPR036236|mint:O95785|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|go:"GO:0030496"(midbody)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990226"(histone methyltransferase binding)|uniprotkb:O95785(identity)|entrezgene/locuslink:58525(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:ftIOu4wVkBWJw+4aHw+R+nN44Vc9606 rogid:FMQwuMDlEC/Zdsnayyl7kpQSmyg9606 intact-crc:5A83CA767B36471A|rigid:tlrFi0tZ3yDerQu8npNLwFjz07w false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JM2 uniprotkb:O43852 intact:EBI-1210359|uniprotkb:Q8N408|uniprotkb:Q5T0T4|intact:EBI-28975500|ensembl:ENSP00000277225 intact:EBI-1171069|uniprotkb:O60456|uniprotkb:Q6FHB9|uniprotkb:Q96RL3|uniprotkb:Q9NR43|intact:EBI-2554631|uniprotkb:B3KPG9|uniprotkb:D6QS48|uniprotkb:D6QS49|uniprotkb:D6QS50|uniprotkb:D6QS51|uniprotkb:D6QS52|uniprotkb:D6QS53|uniprotkb:D6QS54|uniprotkb:D6QS55|uniprotkb:D6QS56|uniprotkb:D6QS57|uniprotkb:D6QS58|uniprotkb:D6QS59|uniprotkb:F5H1Q9|uniprotkb:F5H879|ensembl:ENSP00000249364 psi-mi:zn462_human(display_long)|uniprotkb:ZNF462(gene name)|psi-mi:ZNF462(display_short)|uniprotkb:KIAA1803(gene name synonym)|uniprotkb:Zinc finger PBX1-interacting protein(gene name synonym) psi-mi:calu_human(display_long)|uniprotkb:CALU(gene name)|psi-mi:CALU(display_short)|uniprotkb:Crocalbin(gene name synonym)|uniprotkb:IEF SSP 9302(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8837110|imex:IM-21659-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067047.4|ensembl:ENSP00000277225|ensembl:ENST00000441147|ensembl:ENSP00000397306|refseq:XP_006717278.1|refseq:XP_006717279.1|dip:DIP-39340N|ensembl:ENSG00000148143(gene)|ensembl:ENST00000277225(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q96JM2|rcsb pdb:1X6F|uniprotkb:Q96JM2(identity)|ddbj/embl/genbank:BC036884(identity)|entrezgene/locuslink:58499(identity) refseq:NP_001124146.1|refseq:NP_001186602.1|refseq:NP_001210.1|refseq:NP_001186600.1|refseq:NP_001186601.1|ensembl:ENSG00000128595(gene)|ensembl:ENST00000249364(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016020"(membrane)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0042470"(melanosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR027239|mint:O43852|reactome:R-HSA-114608|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:XP_016868148.1|uniprotkb:O43852(identity)|entrezgene/locuslink:813(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:ftIOu4wVkBWJw+4aHw+R+nN44Vc9606 rogid:lgl1dEYzu+XFHq3QJ/w69xg51Ts9606 intact-crc:5A83CA767B36471A|rigid:tlrFi0tZ3yDerQu8npNLwFjz07w false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JM2 uniprotkb:Q9H582 intact:EBI-1210359|uniprotkb:Q8N408|uniprotkb:Q5T0T4|intact:EBI-28975500|ensembl:ENSP00000277225 intact:EBI-2560435|uniprotkb:Q7LG67|uniprotkb:Q5TCC0|uniprotkb:Q6PI06|uniprotkb:Q9ULJ9|uniprotkb:A2RU71|uniprotkb:Q2TAM0|uniprotkb:Q6P446|uniprotkb:Q6BEP7|ensembl:ENSP00000337008|ensembl:ENSP00000359469 psi-mi:zn462_human(display_long)|uniprotkb:ZNF462(gene name)|psi-mi:ZNF462(display_short)|uniprotkb:KIAA1803(gene name synonym)|uniprotkb:Zinc finger PBX1-interacting protein(gene name synonym) psi-mi:zn644_human(display_long)|uniprotkb:ZNF644(gene name)|psi-mi:ZNF644(display_short)|uniprotkb:KIAA1221(gene name synonym)|uniprotkb:ZEP2(gene name synonym)|uniprotkb:Zinc finger motif enhancer-binding protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8837110|imex:IM-21659-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067047.4|ensembl:ENSP00000277225|ensembl:ENST00000441147|ensembl:ENSP00000397306|refseq:XP_006717278.1|refseq:XP_006717279.1|dip:DIP-39340N|ensembl:ENSG00000148143(gene)|ensembl:ENST00000277225(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q96JM2|rcsb pdb:1X6F|uniprotkb:Q96JM2(identity)|ddbj/embl/genbank:BC036884(identity)|entrezgene/locuslink:58499(identity) refseq:NP_057704.2|refseq:NP_115562.3|refseq:NP_958357.1|refseq:XP_016857977.1|refseq:XP_016857978.1|refseq:XP_016857979.1|refseq:XP_016857980.1|refseq:XP_016857981.1|refseq:XP_016857982.1|refseq:XP_016857983.1|ensembl:ENSG00000122482(gene)|ensembl:ENST00000337393(transcript)|ensembl:ENST00000370440(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9H582|uniprotkb:Q9H582(identity)|entrezgene/locuslink:84146(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:ftIOu4wVkBWJw+4aHw+R+nN44Vc9606 rogid:16MjfkV6aoDArzVV5Qi0K2HI2lg9606 intact-crc:5A83CA767B36471A|rigid:tlrFi0tZ3yDerQu8npNLwFjz07w false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JM2 uniprotkb:O75556 intact:EBI-1210359|uniprotkb:Q8N408|uniprotkb:Q5T0T4|intact:EBI-28975500|ensembl:ENSP00000277225 intact:EBI-8830751|ensembl:ENSP00000244930 psi-mi:zn462_human(display_long)|uniprotkb:ZNF462(gene name)|psi-mi:ZNF462(display_short)|uniprotkb:KIAA1803(gene name synonym)|uniprotkb:Zinc finger PBX1-interacting protein(gene name synonym) psi-mi:sg2a1_human(display_long)|uniprotkb:LIPHC(gene name synonym)|uniprotkb:Lacryglobin(gene name synonym)|uniprotkb:Lipophilin-C(gene name synonym)|uniprotkb:MGB2(gene name synonym)|uniprotkb:Mammaglobin-2(gene name synonym)|uniprotkb:Secretoglobin family 2A member 1(gene name synonym)|uniprotkb:UGB3(gene name synonym)|uniprotkb:SCGB2A1(gene name)|psi-mi:SCGB2A1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8837110|imex:IM-21659-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067047.4|ensembl:ENSP00000277225|ensembl:ENST00000441147|ensembl:ENSP00000397306|refseq:XP_006717278.1|refseq:XP_006717279.1|dip:DIP-39340N|ensembl:ENSG00000148143(gene)|ensembl:ENST00000277225(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q96JM2|rcsb pdb:1X6F|uniprotkb:Q96JM2(identity)|ddbj/embl/genbank:BC036884(identity)|entrezgene/locuslink:58499(identity) refseq:NP_002398.1|ensembl:ENSG00000124939(gene)|ensembl:ENST00000244930(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0030521"(androgen receptor signaling pathway)|interpro:IPR016126(Secretoglobin)|interpro:IPR035960|uniprotkb:O75556(identity)|entrezgene/locuslink:4246(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:ftIOu4wVkBWJw+4aHw+R+nN44Vc9606 rogid:w+3NKAb7Len68q3aS4Re1qKbOac9606 intact-crc:5A83CA767B36471A|rigid:tlrFi0tZ3yDerQu8npNLwFjz07w false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JM2 uniprotkb:Q9UBS4 intact:EBI-1210359|uniprotkb:Q8N408|uniprotkb:Q5T0T4|intact:EBI-28975500|ensembl:ENSP00000277225 intact:EBI-713113|ensembl:ENSP00000265028|ensembl:ENSP00000414398|uniprotkb:Q542Y5|uniprotkb:Q542Y9|uniprotkb:Q6IAQ8|uniprotkb:Q96JC6 psi-mi:zn462_human(display_long)|uniprotkb:ZNF462(gene name)|psi-mi:ZNF462(display_short)|uniprotkb:KIAA1803(gene name synonym)|uniprotkb:Zinc finger PBX1-interacting protein(gene name synonym) psi-mi:djb11_human(display_long)|uniprotkb:HDJ9(gene name synonym)|uniprotkb:DnaJ protein homolog 9(gene name synonym)|uniprotkb:ER-associated Hsp40 co-chaperone(gene name synonym)|uniprotkb:ER-associated DNAJ(gene name synonym)|uniprotkb:HEDJ(gene name synonym)|uniprotkb:Human DnaJ protein 9(gene name synonym)|uniprotkb:PWP1-interacting protein 4(gene name synonym)|uniprotkb:APOBEC1-binding protein 2(gene name synonym)|uniprotkb:PSEC0121(orf name)|uniprotkb:DNAJB11(gene name)|psi-mi:DNAJB11(display_short)|uniprotkb:EDJ(gene name synonym)|uniprotkb:ERJ3(gene name synonym)|uniprotkb:UNQ537/PRO1080(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8837110|imex:IM-21659-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067047.4|ensembl:ENSP00000277225|ensembl:ENST00000441147|ensembl:ENSP00000397306|refseq:XP_006717278.1|refseq:XP_006717279.1|dip:DIP-39340N|ensembl:ENSG00000148143(gene)|ensembl:ENST00000277225(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q96JM2|rcsb pdb:1X6F|uniprotkb:Q96JM2(identity)|ddbj/embl/genbank:BC036884(identity)|entrezgene/locuslink:58499(identity) ensembl:ENSG00000090520(gene)|ensembl:ENST00000265028(transcript)|ensembl:ENST00000439351(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0101031"(chaperone complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:Q9UBS4|reactome:R-HSA-381038|go:"GO:0006457"(protein folding)|refseq:NP_057390.1|dip:DIP-29678N|uniprotkb:Q9UBS4(identity)|entrezgene/locuslink:51726(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:ftIOu4wVkBWJw+4aHw+R+nN44Vc9606 rogid:B8jV6uvPmoGzOEpe4qrMiYloSok9606 intact-crc:5A83CA767B36471A|rigid:tlrFi0tZ3yDerQu8npNLwFjz07w false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JM2 uniprotkb:Q96KQ7 intact:EBI-1210359|uniprotkb:Q8N408|uniprotkb:Q5T0T4|intact:EBI-28975500|ensembl:ENSP00000277225 intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957 psi-mi:zn462_human(display_long)|uniprotkb:ZNF462(gene name)|psi-mi:ZNF462(display_short)|uniprotkb:KIAA1803(gene name synonym)|uniprotkb:Zinc finger PBX1-interacting protein(gene name synonym) psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8837110|imex:IM-21659-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067047.4|ensembl:ENSP00000277225|ensembl:ENST00000441147|ensembl:ENSP00000397306|refseq:XP_006717278.1|refseq:XP_006717279.1|dip:DIP-39340N|ensembl:ENSG00000148143(gene)|ensembl:ENST00000277225(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q96JM2|rcsb pdb:1X6F|uniprotkb:Q96JM2(identity)|ddbj/embl/genbank:BC036884(identity)|entrezgene/locuslink:58499(identity) refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N|uniprotkb:Q96KQ7(identity)|entrezgene/locuslink:10919(identity) psi-mi:"MI:0469"(intact) - - figure legend:Figure 1 and supplementary table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2014/10/16 rogid:ftIOu4wVkBWJw+4aHw+R+nN44Vc9606 rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606 intact-crc:5A83CA767B36471A|rigid:tlrFi0tZ3yDerQu8npNLwFjz07w false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P85037 ensembl:ENSG00000120656 intact:EBI-2509974|ensembl:ENSP00000328720 intact:EBI-8837298 psi-mi:foxk1_human(display_long)|uniprotkb:FOXK1(gene name)|psi-mi:FOXK1(display_short)|uniprotkb:MNF(gene name synonym)|uniprotkb:Myocyte nuclear factor(gene name synonym) psi-mi:taf12_human_gene(display_short)|psi-mi:ENSG00000120656(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8837282|imex:IM-21659-81 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) ensembl:ENSG00000164916(gene)|ensembl:ENST00000328914(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0042594"(response to starvation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5689603|refseq:XP_011513493.1|refseq:NP_001032242.1 - - - - figure legend:4d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2016/08/15 rogid:ngoE3oNlIDGkTf1ZMYG4OQ6lvE09606 - intact-crc:0860CFAA65D09C7F false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) ensembl:ENSG00000120656 uniprotkb:Q8IXJ9 intact:EBI-8837298 intact:EBI-1646500|uniprotkb:Q5JWS9|uniprotkb:Q8IYY7|uniprotkb:Q9H466|uniprotkb:Q9NQF8|uniprotkb:Q9UFJ0|uniprotkb:Q9UFP8|uniprotkb:Q9Y2I4|uniprotkb:B2RP59|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978 psi-mi:taf12_human_gene(display_short)|psi-mi:ENSG00000120656(display_long) psi-mi:asxl1_human(display_long)|uniprotkb:ASXL1(gene name)|psi-mi:ASXL1(display_short)|uniprotkb:KIAA0978(gene name synonym)|uniprotkb:Additional sex combs-like protein 1(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8837288|imex:IM-21659-83 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_056153.2|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978|dip:DIP-46910N|ensembl:ENSG00000171456(gene)|ensembl:ENST00000375687(transcript)|ensembl:ENST00000613218(transcript)|ensembl:ENST00000620121(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035359"(negative regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0035564"(regulation of kidney size)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048538"(thymus development)|go:"GO:0048539"(bone marrow development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060430"(lung saccule development)|go:"GO:0072015"(glomerular visceral epithelial cell development)|interpro:IPR007759(DNA-directed RNA polymerase delta subunit)|interpro:IPR024811|interpro:IPR024815|interpro:IPR026905|interpro:IPR028020|interpro:IPR044867|reactome:R-HSA-5689603|go:"GO:0048386"(positive regulation of retinoic acid receptor signaling pathway) - - - figure legend:4d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 - rogid:6YpSgdOhNRawROUe3W0t72u6JfA9606 intact-crc:88A069D91AAC8567 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) ensembl:ENSG00000172409 uniprotkb:Q8IXJ9 intact:EBI-8837300 intact:EBI-1646500|uniprotkb:Q5JWS9|uniprotkb:Q8IYY7|uniprotkb:Q9H466|uniprotkb:Q9NQF8|uniprotkb:Q9UFJ0|uniprotkb:Q9UFP8|uniprotkb:Q9Y2I4|uniprotkb:B2RP59|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978 psi-mi:clp1_human_gene(display_short)|psi-mi:ENSG00000172409(display_long) psi-mi:asxl1_human(display_long)|uniprotkb:ASXL1(gene name)|psi-mi:ASXL1(display_short)|uniprotkb:KIAA0978(gene name synonym)|uniprotkb:Additional sex combs-like protein 1(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12506033|imex:IM-21659-65 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_056153.2|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978|dip:DIP-46910N|ensembl:ENSG00000171456(gene)|ensembl:ENST00000375687(transcript)|ensembl:ENST00000613218(transcript)|ensembl:ENST00000620121(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035359"(negative regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0035564"(regulation of kidney size)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048538"(thymus development)|go:"GO:0048539"(bone marrow development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060430"(lung saccule development)|go:"GO:0072015"(glomerular visceral epithelial cell development)|interpro:IPR007759(DNA-directed RNA polymerase delta subunit)|interpro:IPR024811|interpro:IPR024815|interpro:IPR026905|interpro:IPR028020|interpro:IPR044867|reactome:R-HSA-5689603|go:"GO:0048386"(positive regulation of retinoic acid receptor signaling pathway) - - - figure legend:4d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 - rogid:6YpSgdOhNRawROUe3W0t72u6JfA9606 - false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) ensembl:ENSG00000073111 uniprotkb:Q8IXJ9 intact:EBI-8837302 intact:EBI-1646500|uniprotkb:Q5JWS9|uniprotkb:Q8IYY7|uniprotkb:Q9H466|uniprotkb:Q9NQF8|uniprotkb:Q9UFJ0|uniprotkb:Q9UFP8|uniprotkb:Q9Y2I4|uniprotkb:B2RP59|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978 psi-mi:mcm2_human_gene(display_short)|psi-mi:ENSG00000073111(display_long) psi-mi:asxl1_human(display_long)|uniprotkb:ASXL1(gene name)|psi-mi:ASXL1(display_short)|uniprotkb:KIAA0978(gene name synonym)|uniprotkb:Additional sex combs-like protein 1(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12506038|imex:IM-21659-67 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_056153.2|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978|dip:DIP-46910N|ensembl:ENSG00000171456(gene)|ensembl:ENST00000375687(transcript)|ensembl:ENST00000613218(transcript)|ensembl:ENST00000620121(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035359"(negative regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0035564"(regulation of kidney size)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048538"(thymus development)|go:"GO:0048539"(bone marrow development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060430"(lung saccule development)|go:"GO:0072015"(glomerular visceral epithelial cell development)|interpro:IPR007759(DNA-directed RNA polymerase delta subunit)|interpro:IPR024811|interpro:IPR024815|interpro:IPR026905|interpro:IPR028020|interpro:IPR044867|reactome:R-HSA-5689603|go:"GO:0048386"(positive regulation of retinoic acid receptor signaling pathway) - - - figure legend:4d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 - rogid:6YpSgdOhNRawROUe3W0t72u6JfA9606 - false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) ensembl:ENSG00000147669 uniprotkb:Q8IXJ9 intact:EBI-8837296 intact:EBI-1646500|uniprotkb:Q5JWS9|uniprotkb:Q8IYY7|uniprotkb:Q9H466|uniprotkb:Q9NQF8|uniprotkb:Q9UFJ0|uniprotkb:Q9UFP8|uniprotkb:Q9Y2I4|uniprotkb:B2RP59|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978 psi-mi:polr2k_human_gene(display_short)|psi-mi:ENSG00000147669(display_long) psi-mi:asxl1_human(display_long)|uniprotkb:ASXL1(gene name)|psi-mi:ASXL1(display_short)|uniprotkb:KIAA0978(gene name synonym)|uniprotkb:Additional sex combs-like protein 1(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12506043|imex:IM-21659-69 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_056153.2|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978|dip:DIP-46910N|ensembl:ENSG00000171456(gene)|ensembl:ENST00000375687(transcript)|ensembl:ENST00000613218(transcript)|ensembl:ENST00000620121(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035359"(negative regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0035564"(regulation of kidney size)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048538"(thymus development)|go:"GO:0048539"(bone marrow development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060430"(lung saccule development)|go:"GO:0072015"(glomerular visceral epithelial cell development)|interpro:IPR007759(DNA-directed RNA polymerase delta subunit)|interpro:IPR024811|interpro:IPR024815|interpro:IPR026905|interpro:IPR028020|interpro:IPR044867|reactome:R-HSA-5689603|go:"GO:0048386"(positive regulation of retinoic acid receptor signaling pathway) - - - figure legend:4d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 - rogid:6YpSgdOhNRawROUe3W0t72u6JfA9606 - false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) ensembl:ENSG00000116251 uniprotkb:Q8IXJ9 intact:EBI-8837294 intact:EBI-1646500|uniprotkb:Q5JWS9|uniprotkb:Q8IYY7|uniprotkb:Q9H466|uniprotkb:Q9NQF8|uniprotkb:Q9UFJ0|uniprotkb:Q9UFP8|uniprotkb:Q9Y2I4|uniprotkb:B2RP59|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978 psi-mi:rpl22_human_gene(display_short)|psi-mi:ENSG00000116251(display_long) psi-mi:asxl1_human(display_long)|uniprotkb:ASXL1(gene name)|psi-mi:ASXL1(display_short)|uniprotkb:KIAA0978(gene name synonym)|uniprotkb:Additional sex combs-like protein 1(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12506048|imex:IM-21659-71 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_056153.2|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978|dip:DIP-46910N|ensembl:ENSG00000171456(gene)|ensembl:ENST00000375687(transcript)|ensembl:ENST00000613218(transcript)|ensembl:ENST00000620121(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035359"(negative regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0035564"(regulation of kidney size)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048538"(thymus development)|go:"GO:0048539"(bone marrow development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060430"(lung saccule development)|go:"GO:0072015"(glomerular visceral epithelial cell development)|interpro:IPR007759(DNA-directed RNA polymerase delta subunit)|interpro:IPR024811|interpro:IPR024815|interpro:IPR026905|interpro:IPR028020|interpro:IPR044867|reactome:R-HSA-5689603|go:"GO:0048386"(positive regulation of retinoic acid receptor signaling pathway) - - - figure legend:4d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2018/04/06 - rogid:6YpSgdOhNRawROUe3W0t72u6JfA9606 - false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P85037 ensembl:ENSG00000172409 intact:EBI-2509974|ensembl:ENSP00000328720 intact:EBI-8837300 psi-mi:foxk1_human(display_long)|uniprotkb:FOXK1(gene name)|psi-mi:FOXK1(display_short)|uniprotkb:MNF(gene name synonym)|uniprotkb:Myocyte nuclear factor(gene name synonym) psi-mi:clp1_human_gene(display_short)|psi-mi:ENSG00000172409(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12506053|imex:IM-21659-73 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) ensembl:ENSG00000164916(gene)|ensembl:ENST00000328914(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0042594"(response to starvation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5689603|refseq:XP_011513493.1|refseq:NP_001032242.1 - - - - figure legend:4d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2016/08/15 rogid:ngoE3oNlIDGkTf1ZMYG4OQ6lvE09606 - - false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P85037 ensembl:ENSG00000073111 intact:EBI-2509974|ensembl:ENSP00000328720 intact:EBI-8837302 psi-mi:foxk1_human(display_long)|uniprotkb:FOXK1(gene name)|psi-mi:FOXK1(display_short)|uniprotkb:MNF(gene name synonym)|uniprotkb:Myocyte nuclear factor(gene name synonym) psi-mi:mcm2_human_gene(display_short)|psi-mi:ENSG00000073111(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12506058|imex:IM-21659-75 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) ensembl:ENSG00000164916(gene)|ensembl:ENST00000328914(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0042594"(response to starvation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5689603|refseq:XP_011513493.1|refseq:NP_001032242.1 - - - - figure legend:4d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2016/08/15 rogid:ngoE3oNlIDGkTf1ZMYG4OQ6lvE09606 - - false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P85037 ensembl:ENSG00000147669 intact:EBI-2509974|ensembl:ENSP00000328720 intact:EBI-8837296 psi-mi:foxk1_human(display_long)|uniprotkb:FOXK1(gene name)|psi-mi:FOXK1(display_short)|uniprotkb:MNF(gene name synonym)|uniprotkb:Myocyte nuclear factor(gene name synonym) psi-mi:polr2k_human_gene(display_short)|psi-mi:ENSG00000147669(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12506063|imex:IM-21659-77 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) ensembl:ENSG00000164916(gene)|ensembl:ENST00000328914(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0042594"(response to starvation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5689603|refseq:XP_011513493.1|refseq:NP_001032242.1 - - - - figure legend:4d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2016/08/15 rogid:ngoE3oNlIDGkTf1ZMYG4OQ6lvE09606 - - false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P85037 ensembl:ENSG00000116251 intact:EBI-2509974|ensembl:ENSP00000328720 intact:EBI-8837294 psi-mi:foxk1_human(display_long)|uniprotkb:FOXK1(gene name)|psi-mi:FOXK1(display_short)|uniprotkb:MNF(gene name synonym)|uniprotkb:Myocyte nuclear factor(gene name synonym) psi-mi:rpl22_human_gene(display_short)|psi-mi:ENSG00000116251(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Hauri et al. pubmed:27705803|imex:IM-21659 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-12506068|imex:IM-21659-79 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) ensembl:ENSG00000164916(gene)|ensembl:ENST00000328914(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0042594"(response to starvation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-5689603|refseq:XP_011513493.1|refseq:NP_001032242.1 - - - - figure legend:4d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/28 2016/08/15 rogid:ngoE3oNlIDGkTf1ZMYG4OQ6lvE09606 - - false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)