#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P21836 uniprotkb:P02469 intact:EBI-7345845|intact:MINT-1206315|ensembl:ENSMUSP00000024099|ensembl:ENSMUSP00000083097 intact:EBI-6662997|ensembl:ENSMUSP00000002979|ensembl:ENSMUSP00000132778|uniprotkb:E9PXZ9 psi-mi:aces_mouse(display_long)|uniprotkb:Ache(gene name)|psi-mi:Ache(display_short) psi-mi:lamb1_mouse(display_long)|uniprotkb:Lamb1(gene name)|psi-mi:Lamb1(display_short)|uniprotkb:Lamb-1(gene name synonym)|uniprotkb:Lamb1-1(gene name synonym)|uniprotkb:Laminin B1 chain(gene name synonym)|uniprotkb:Laminin-1 subunit beta(gene name synonym)|uniprotkb:Laminin-10 subunit beta(gene name synonym)|uniprotkb:Laminin-12 subunit beta(gene name synonym)|uniprotkb:Laminin-2 subunit beta(gene name synonym)|uniprotkb:Laminin-6 subunit beta(gene name synonym)|uniprotkb:Laminin-8 subunit beta(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paraoanu et al. (2004) pubmed:15474030|imex:IM-13916|mint:MINT-5217232 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7345987|mint:MINT-50576|imex:IM-13916-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033729.1|ensembl:ENSMUSG00000023328(gene)|ensembl:ENSMUST00000024099(transcript)|ensembl:ENSMUST00000085934(transcript)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0002076"(osteoblast development)|go:"GO:0003990"(acetylcholinesterase activity)|go:"GO:0004104"(cholinesterase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006581"(acetylcholine catabolic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007416"(synapse assembly)|go:"GO:0008291"(acetylcholine metabolic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0019695"(choline metabolic process)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0033265"(choline binding)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043236"(laminin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070997"(neuron death)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000997(Cholinesterase)|interpro:IPR002018(Carboxylesterase, type B)|interpro:IPR014788(Acetylcholinesterase, tetramerisation)|interpro:IPR019819|interpro:IPR019826|interpro:IPR029058|mint:P21836|rcsb pdb:1C2B|rcsb pdb:1C2O|rcsb pdb:1J06|rcsb pdb:1J07|rcsb pdb:1KU6|rcsb pdb:1MAA|rcsb pdb:1MAH|rcsb pdb:1N5M|rcsb pdb:1N5R|rcsb pdb:1Q83|rcsb pdb:1Q84|rcsb pdb:2C0P|rcsb pdb:2C0Q|rcsb pdb:2GYU|rcsb pdb:2GYV|rcsb pdb:2GYW|rcsb pdb:2H9Y|rcsb pdb:2HA0|rcsb pdb:2HA2|rcsb pdb:2HA3|rcsb pdb:2HA4|rcsb pdb:2HA5|rcsb pdb:2HA6|rcsb pdb:2HA7|rcsb pdb:2JEY|rcsb pdb:2JEZ|rcsb pdb:2JF0|rcsb pdb:2JGE|rcsb pdb:2JGF|rcsb pdb:2JGI|rcsb pdb:2JGJ|rcsb pdb:2JGL|rcsb pdb:2JGM|rcsb pdb:2WHP|rcsb pdb:2WHQ|rcsb pdb:2WHR|rcsb pdb:2WLS|rcsb pdb:2WU3|rcsb pdb:2WU4|rcsb pdb:2XUD|rcsb pdb:2XUF|rcsb pdb:2XUG|rcsb pdb:2XUH|rcsb pdb:2XUI|rcsb pdb:2XUJ|rcsb pdb:2XUK|rcsb pdb:2XUO|rcsb pdb:2XUP|rcsb pdb:2XUQ|rcsb pdb:2Y2U|rcsb pdb:2Y2V|rcsb pdb:3DL4|rcsb pdb:3DL7|rcsb pdb:3ZLT|rcsb pdb:3ZLU|rcsb pdb:3ZLV|rcsb pdb:4A16|rcsb pdb:4A23|rcsb pdb:4ARA|rcsb pdb:4ARB|rcsb pdb:4B7Z|rcsb pdb:4B80|rcsb pdb:4B81|rcsb pdb:4B82|rcsb pdb:4B83|rcsb pdb:4B84|rcsb pdb:4B85|rcsb pdb:4BC0|rcsb pdb:4BC1|rcsb pdb:4BTL|rcsb pdb:5DTI|rcsb pdb:5DTJ|rcsb pdb:5EHN|rcsb pdb:5EHQ|rcsb pdb:5EHZ|rcsb pdb:5EIA|rcsb pdb:5EIE|rcsb pdb:5EIH|rcsb pdb:5FKJ|rcsb pdb:5FPP|rcsb pdb:5FUM|rcsb pdb:5HCU|rcsb pdb:5OV9|rcsb pdb:6FSD|rcsb pdb:6FSE|rcsb pdb:6TD2|rcsb pdb:2JGK|refseq:NP_001276939.1|mint:MINT-1206353(identity) refseq:XP_006515055.2|ensembl:ENSMUSG00000002900(gene)|ensembl:ENSMUST00000002979(transcript)|ensembl:ENSMUST00000169088(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005606"(laminin-1 complex)|go:"GO:0005607"(laminin-2 complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007566"(embryo implantation)|go:"GO:0007611"(learning or memory)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016477"(cell migration)|go:"GO:0019899"(enzyme binding)|go:"GO:0021812"(neuronal-glial interaction involved in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031175"(neuron projection development)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042476"(odontogenesis)|go:"GO:0043208"(glycosphingolipid binding)|go:"GO:0043256"(laminin complex)|go:"GO:0043257"(laminin-8 complex)|go:"GO:0043259"(laminin-10 complex)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0062023"(collagen-containing extracellular matrix)|reactome:R-MMU-3000157|reactome:R-MMU-381426|reactome:R-MMU-8874081|go:"GO:0070831"(basement membrane assembly)|reactome:R-MMU-8957275|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR013015(Laminin IV)|mint:P02469|rcsb pdb:4AQS|rcsb pdb:5MC9|refseq:XP_006515056.1|mint:MINT-1206361(identity) - comment:mint|function:Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1|comment:domains range from SwissProt Feature table viewer and paper Results.|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2004/11/29 2014/10/16 rogid:f+Cjyy+U1wBxttirNKyM/PabkNs10090 rogid:cUuVqY2JMeRrS9sDYudPy7hSIL010090 intact-crc:235EC94220897E61|rigid:isNoclF1FwynogAcHgB7RXHT/Mo false tag:?-?(MINT-1206356)|binding-associated region:155-418(MINT-1206354) tag:?-?(MINT-1206366)|binding-associated region:?-?(MINT-1206362) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P21836 uniprotkb:P02469 intact:EBI-7345845|intact:MINT-1206315|ensembl:ENSMUSP00000024099|ensembl:ENSMUSP00000083097 intact:EBI-6662997|ensembl:ENSMUSP00000002979|ensembl:ENSMUSP00000132778|uniprotkb:E9PXZ9 psi-mi:aces_mouse(display_long)|uniprotkb:Ache(gene name)|psi-mi:Ache(display_short) psi-mi:lamb1_mouse(display_long)|uniprotkb:Lamb1(gene name)|psi-mi:Lamb1(display_short)|uniprotkb:Lamb-1(gene name synonym)|uniprotkb:Lamb1-1(gene name synonym)|uniprotkb:Laminin B1 chain(gene name synonym)|uniprotkb:Laminin-1 subunit beta(gene name synonym)|uniprotkb:Laminin-10 subunit beta(gene name synonym)|uniprotkb:Laminin-12 subunit beta(gene name synonym)|uniprotkb:Laminin-2 subunit beta(gene name synonym)|uniprotkb:Laminin-6 subunit beta(gene name synonym)|uniprotkb:Laminin-8 subunit beta(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Paraoanu et al. (2004) pubmed:15474030|imex:IM-13916|mint:MINT-5217232 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7346050|mint:MINT-50596|imex:IM-13916-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033729.1|ensembl:ENSMUSG00000023328(gene)|ensembl:ENSMUST00000024099(transcript)|ensembl:ENSMUST00000085934(transcript)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0002076"(osteoblast development)|go:"GO:0003990"(acetylcholinesterase activity)|go:"GO:0004104"(cholinesterase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006581"(acetylcholine catabolic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007416"(synapse assembly)|go:"GO:0008291"(acetylcholine metabolic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0019695"(choline metabolic process)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0033265"(choline binding)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043236"(laminin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070997"(neuron death)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000997(Cholinesterase)|interpro:IPR002018(Carboxylesterase, type B)|interpro:IPR014788(Acetylcholinesterase, tetramerisation)|interpro:IPR019819|interpro:IPR019826|interpro:IPR029058|mint:P21836|rcsb pdb:1C2B|rcsb pdb:1C2O|rcsb pdb:1J06|rcsb pdb:1J07|rcsb pdb:1KU6|rcsb pdb:1MAA|rcsb pdb:1MAH|rcsb pdb:1N5M|rcsb pdb:1N5R|rcsb pdb:1Q83|rcsb pdb:1Q84|rcsb pdb:2C0P|rcsb pdb:2C0Q|rcsb pdb:2GYU|rcsb pdb:2GYV|rcsb pdb:2GYW|rcsb pdb:2H9Y|rcsb pdb:2HA0|rcsb pdb:2HA2|rcsb pdb:2HA3|rcsb pdb:2HA4|rcsb pdb:2HA5|rcsb pdb:2HA6|rcsb pdb:2HA7|rcsb pdb:2JEY|rcsb pdb:2JEZ|rcsb pdb:2JF0|rcsb pdb:2JGE|rcsb pdb:2JGF|rcsb pdb:2JGI|rcsb pdb:2JGJ|rcsb pdb:2JGL|rcsb pdb:2JGM|rcsb pdb:2WHP|rcsb pdb:2WHQ|rcsb pdb:2WHR|rcsb pdb:2WLS|rcsb pdb:2WU3|rcsb pdb:2WU4|rcsb pdb:2XUD|rcsb pdb:2XUF|rcsb pdb:2XUG|rcsb pdb:2XUH|rcsb pdb:2XUI|rcsb pdb:2XUJ|rcsb pdb:2XUK|rcsb pdb:2XUO|rcsb pdb:2XUP|rcsb pdb:2XUQ|rcsb pdb:2Y2U|rcsb pdb:2Y2V|rcsb pdb:3DL4|rcsb pdb:3DL7|rcsb pdb:3ZLT|rcsb pdb:3ZLU|rcsb pdb:3ZLV|rcsb pdb:4A16|rcsb pdb:4A23|rcsb pdb:4ARA|rcsb pdb:4ARB|rcsb pdb:4B7Z|rcsb pdb:4B80|rcsb pdb:4B81|rcsb pdb:4B82|rcsb pdb:4B83|rcsb pdb:4B84|rcsb pdb:4B85|rcsb pdb:4BC0|rcsb pdb:4BC1|rcsb pdb:4BTL|rcsb pdb:5DTI|rcsb pdb:5DTJ|rcsb pdb:5EHN|rcsb pdb:5EHQ|rcsb pdb:5EHZ|rcsb pdb:5EIA|rcsb pdb:5EIE|rcsb pdb:5EIH|rcsb pdb:5FKJ|rcsb pdb:5FPP|rcsb pdb:5FUM|rcsb pdb:5HCU|rcsb pdb:5OV9|rcsb pdb:6FSD|rcsb pdb:6FSE|rcsb pdb:6TD2|rcsb pdb:2JGK|refseq:NP_001276939.1|mint:MINT-1206377(identity) refseq:XP_006515055.2|ensembl:ENSMUSG00000002900(gene)|ensembl:ENSMUST00000002979(transcript)|ensembl:ENSMUST00000169088(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005606"(laminin-1 complex)|go:"GO:0005607"(laminin-2 complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007566"(embryo implantation)|go:"GO:0007611"(learning or memory)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016477"(cell migration)|go:"GO:0019899"(enzyme binding)|go:"GO:0021812"(neuronal-glial interaction involved in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031175"(neuron projection development)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042476"(odontogenesis)|go:"GO:0043208"(glycosphingolipid binding)|go:"GO:0043256"(laminin complex)|go:"GO:0043257"(laminin-8 complex)|go:"GO:0043259"(laminin-10 complex)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0062023"(collagen-containing extracellular matrix)|reactome:R-MMU-3000157|reactome:R-MMU-381426|reactome:R-MMU-8874081|go:"GO:0070831"(basement membrane assembly)|reactome:R-MMU-8957275|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR013015(Laminin IV)|mint:P02469|rcsb pdb:4AQS|rcsb pdb:5MC9|refseq:XP_006515056.1|mint:MINT-1206381(identity) - comment:mint|function:Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2004/11/29 2014/10/16 rogid:f+Cjyy+U1wBxttirNKyM/PabkNs10090 rogid:cUuVqY2JMeRrS9sDYudPy7hSIL010090 intact-crc:BF59EFF09C9BB198|rigid:isNoclF1FwynogAcHgB7RXHT/Mo false - - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:P21836 uniprotkb:P02469 intact:EBI-7345845|intact:MINT-1206315|ensembl:ENSMUSP00000024099|ensembl:ENSMUSP00000083097 intact:EBI-6662997|ensembl:ENSMUSP00000002979|ensembl:ENSMUSP00000132778|uniprotkb:E9PXZ9 psi-mi:aces_mouse(display_long)|uniprotkb:Ache(gene name)|psi-mi:Ache(display_short) psi-mi:lamb1_mouse(display_long)|uniprotkb:Lamb1(gene name)|psi-mi:Lamb1(display_short)|uniprotkb:Lamb-1(gene name synonym)|uniprotkb:Lamb1-1(gene name synonym)|uniprotkb:Laminin B1 chain(gene name synonym)|uniprotkb:Laminin-1 subunit beta(gene name synonym)|uniprotkb:Laminin-10 subunit beta(gene name synonym)|uniprotkb:Laminin-12 subunit beta(gene name synonym)|uniprotkb:Laminin-2 subunit beta(gene name synonym)|uniprotkb:Laminin-6 subunit beta(gene name synonym)|uniprotkb:Laminin-8 subunit beta(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Paraoanu et al. (2004) pubmed:15474030|imex:IM-13916|mint:MINT-5217232 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7346253|mint:MINT-50597|imex:IM-13916-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033729.1|ensembl:ENSMUSG00000023328(gene)|ensembl:ENSMUST00000024099(transcript)|ensembl:ENSMUST00000085934(transcript)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0002076"(osteoblast development)|go:"GO:0003990"(acetylcholinesterase activity)|go:"GO:0004104"(cholinesterase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006581"(acetylcholine catabolic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007416"(synapse assembly)|go:"GO:0008291"(acetylcholine metabolic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0019695"(choline metabolic process)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0033265"(choline binding)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043236"(laminin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070997"(neuron death)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000997(Cholinesterase)|interpro:IPR002018(Carboxylesterase, type B)|interpro:IPR014788(Acetylcholinesterase, tetramerisation)|interpro:IPR019819|interpro:IPR019826|interpro:IPR029058|mint:P21836|rcsb pdb:1C2B|rcsb pdb:1C2O|rcsb pdb:1J06|rcsb pdb:1J07|rcsb pdb:1KU6|rcsb pdb:1MAA|rcsb pdb:1MAH|rcsb pdb:1N5M|rcsb pdb:1N5R|rcsb pdb:1Q83|rcsb pdb:1Q84|rcsb pdb:2C0P|rcsb pdb:2C0Q|rcsb pdb:2GYU|rcsb pdb:2GYV|rcsb pdb:2GYW|rcsb pdb:2H9Y|rcsb pdb:2HA0|rcsb pdb:2HA2|rcsb pdb:2HA3|rcsb pdb:2HA4|rcsb pdb:2HA5|rcsb pdb:2HA6|rcsb pdb:2HA7|rcsb pdb:2JEY|rcsb pdb:2JEZ|rcsb pdb:2JF0|rcsb pdb:2JGE|rcsb pdb:2JGF|rcsb pdb:2JGI|rcsb pdb:2JGJ|rcsb pdb:2JGL|rcsb pdb:2JGM|rcsb pdb:2WHP|rcsb pdb:2WHQ|rcsb pdb:2WHR|rcsb pdb:2WLS|rcsb pdb:2WU3|rcsb pdb:2WU4|rcsb pdb:2XUD|rcsb pdb:2XUF|rcsb pdb:2XUG|rcsb pdb:2XUH|rcsb pdb:2XUI|rcsb pdb:2XUJ|rcsb pdb:2XUK|rcsb pdb:2XUO|rcsb pdb:2XUP|rcsb pdb:2XUQ|rcsb pdb:2Y2U|rcsb pdb:2Y2V|rcsb pdb:3DL4|rcsb pdb:3DL7|rcsb pdb:3ZLT|rcsb pdb:3ZLU|rcsb pdb:3ZLV|rcsb pdb:4A16|rcsb pdb:4A23|rcsb pdb:4ARA|rcsb pdb:4ARB|rcsb pdb:4B7Z|rcsb pdb:4B80|rcsb pdb:4B81|rcsb pdb:4B82|rcsb pdb:4B83|rcsb pdb:4B84|rcsb pdb:4B85|rcsb pdb:4BC0|rcsb pdb:4BC1|rcsb pdb:4BTL|rcsb pdb:5DTI|rcsb pdb:5DTJ|rcsb pdb:5EHN|rcsb pdb:5EHQ|rcsb pdb:5EHZ|rcsb pdb:5EIA|rcsb pdb:5EIE|rcsb pdb:5EIH|rcsb pdb:5FKJ|rcsb pdb:5FPP|rcsb pdb:5FUM|rcsb pdb:5HCU|rcsb pdb:5OV9|rcsb pdb:6FSD|rcsb pdb:6FSE|rcsb pdb:6TD2|rcsb pdb:2JGK|refseq:NP_001276939.1|mint:MINT-1206390(identity) refseq:XP_006515055.2|ensembl:ENSMUSG00000002900(gene)|ensembl:ENSMUST00000002979(transcript)|ensembl:ENSMUST00000169088(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005606"(laminin-1 complex)|go:"GO:0005607"(laminin-2 complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007566"(embryo implantation)|go:"GO:0007611"(learning or memory)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016477"(cell migration)|go:"GO:0019899"(enzyme binding)|go:"GO:0021812"(neuronal-glial interaction involved in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031175"(neuron projection development)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042476"(odontogenesis)|go:"GO:0043208"(glycosphingolipid binding)|go:"GO:0043256"(laminin complex)|go:"GO:0043257"(laminin-8 complex)|go:"GO:0043259"(laminin-10 complex)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0062023"(collagen-containing extracellular matrix)|reactome:R-MMU-3000157|reactome:R-MMU-381426|reactome:R-MMU-8874081|go:"GO:0070831"(basement membrane assembly)|reactome:R-MMU-8957275|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR013015(Laminin IV)|mint:P02469|rcsb pdb:4AQS|rcsb pdb:5MC9|refseq:XP_006515056.1|mint:MINT-1206394(identity) - comment:mint|function:Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2B|comment:- 160.80.34.149|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2004/11/29 2014/10/16 rogid:f+Cjyy+U1wBxttirNKyM/PabkNs10090 rogid:cUuVqY2JMeRrS9sDYudPy7hSIL010090 intact-crc:C53CE9CCF476EAF1|rigid:isNoclF1FwynogAcHgB7RXHT/Mo false - - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot)