#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P34709	uniprotkb:P34691	intact:EBI-367223|uniprotkb:Q8STA8|uniprotkb:Q8STE2|uniprotkb:Q8T5X5|uniprotkb:Q8T5X6|uniprotkb:Q8T5X7|uniprotkb:Q8T5X8|uniprotkb:Q8T5X9|uniprotkb:Q8T5Y0|uniprotkb:Q8T5Y1|uniprotkb:Q8T5Y2|uniprotkb:Q8T5Y3|uniprotkb:Q8T5Y4|uniprotkb:Q8T5Y5|uniprotkb:Q9N5Y5|ensemblmetazoa:C15F1.3a.1	intact:EBI-445465|ensemblmetazoa:C01F6.4a.1	psi-mi:tra2_caeel(display_long)|uniprotkb:tra-2(gene name)|psi-mi:tra-2(display_short)|uniprotkb:C15F1.3(orf name)|uniprotkb:Ce-Tra-2(gene name synonym)	psi-mi:fem3_caeel(display_long)|uniprotkb:Feminization of XX and XO animals protein 3(gene name synonym)|uniprotkb:Ce-FEM-3(gene name synonym)|uniprotkb:C01F6.4(orf name)|uniprotkb:fem-3(gene name)|psi-mi:fem-3(display_short)	psi-mi:"MI:0019"(coimmunoprecipitation)	Mehra et al. (1999)	pubmed:10364161	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-445472	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001021954.1|refseq:NP_495426.1|wormbase:C15F1.3a|wormbase:C15F1.3b|interpro:IPR032848|ensemblmetazoa:C15F1.3a.1(transcript)|ensemblmetazoa:WBGene00006605(gene)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007530"(sex determination)|go:"GO:0007548"(sex differentiation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018992"(germ-line sex determination)|go:"GO:0030154"(cell differentiation)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040021"(hermaphrodite germ-line sex determination)|go:"GO:0042001"(hermaphrodite somatic sex determination)|go:"GO:0044214"(spanning component of plasma membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)	ensemblmetazoa:C01F6.4a.1(transcript)|ensemblmetazoa:WBGene00001413(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007548"(sex differentiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030238"(male sex determination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043406"(positive regulation of MAP kinase activity)|interpro:IPR030804|refseq:NP_001255365.1|wormbase:C01F6.4a|go:"GO:0060282"(positive regulation of oocyte development)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1904146"(positive regulation of meiotic cell cycle process involved in oocyte maturation)|go:"GO:1905936"(regulation of germ cell proliferation)	-	-	-	comment:Shows that the c-terminal domain of tra-2 can associate with fem-3.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/09/10	2014/10/16	rogid:AfAwcrMV8QNzg5YkaaGyPHuWPow6239	rogid:3WeE4VQ4oQC4FjKX7mUkJ/kWfGo6239	intact-crc:B29CAD4CC2321130|rigid:Qlw8a14/78jUGPiqsQd3XGc4ju0	false	35s radiolabel:?-?|sufficient binding region:1133-1475	35s radiolabel:?-?|myc tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P34691	uniprotkb:P34709	intact:EBI-445465|ensemblmetazoa:C01F6.4a.1	intact:EBI-367223|uniprotkb:Q8STA8|uniprotkb:Q8STE2|uniprotkb:Q8T5X5|uniprotkb:Q8T5X6|uniprotkb:Q8T5X7|uniprotkb:Q8T5X8|uniprotkb:Q8T5X9|uniprotkb:Q8T5Y0|uniprotkb:Q8T5Y1|uniprotkb:Q8T5Y2|uniprotkb:Q8T5Y3|uniprotkb:Q8T5Y4|uniprotkb:Q8T5Y5|uniprotkb:Q9N5Y5|ensemblmetazoa:C15F1.3a.1	psi-mi:fem3_caeel(display_long)|uniprotkb:Feminization of XX and XO animals protein 3(gene name synonym)|uniprotkb:Ce-FEM-3(gene name synonym)|uniprotkb:C01F6.4(orf name)|uniprotkb:fem-3(gene name)|psi-mi:fem-3(display_short)	psi-mi:tra2_caeel(display_long)|uniprotkb:tra-2(gene name)|psi-mi:tra-2(display_short)|uniprotkb:C15F1.3(orf name)|uniprotkb:Ce-Tra-2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Mehra et al. (1999)	pubmed:10364161	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-445480	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:C01F6.4a.1(transcript)|ensemblmetazoa:WBGene00001413(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007548"(sex differentiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030238"(male sex determination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043406"(positive regulation of MAP kinase activity)|interpro:IPR030804|refseq:NP_001255365.1|wormbase:C01F6.4a|go:"GO:0060282"(positive regulation of oocyte development)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1904146"(positive regulation of meiotic cell cycle process involved in oocyte maturation)|go:"GO:1905936"(regulation of germ cell proliferation)	refseq:NP_001021954.1|refseq:NP_495426.1|wormbase:C15F1.3a|wormbase:C15F1.3b|interpro:IPR032848|ensemblmetazoa:C15F1.3a.1(transcript)|ensemblmetazoa:WBGene00006605(gene)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007530"(sex determination)|go:"GO:0007548"(sex differentiation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018992"(germ-line sex determination)|go:"GO:0030154"(cell differentiation)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040021"(hermaphrodite germ-line sex determination)|go:"GO:0042001"(hermaphrodite somatic sex determination)|go:"GO:0044214"(spanning component of plasma membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)	-	-	-	comment:A 141 AA region of tra-2 was able to interact with 1-343AA of fem-3. Deletion of AA 1-69 or 309-388 in fem-3 inhibited binding to tra-2.	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2004/09/10	2014/10/16	rogid:3WeE4VQ4oQC4FjKX7mUkJ/kWfGo6239	rogid:AfAwcrMV8QNzg5YkaaGyPHuWPow6239	intact-crc:398F385B00D21A25|rigid:Qlw8a14/78jUGPiqsQd3XGc4ju0	false	binding-associated region:1-343|necessary binding region:1-69,?-?	binding-associated region:1133-1273	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)