DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Cryo-EM structures of the ATP release channel pannexin 1. Cryo-EM structures of the ATP release channel pannexin 1. Nature structural & molecular biology 2020 imex curation Deng Z., He Z., Maksaev G., Bitter RM., Rau M., Fitzpatrick JAJ., Yuan P. yuanp@wustl.edu 24-May-2021: Contacted by IntAct-Help. Only protein-protein interactions imex curation picpa Pichia pastoris (Yeast) Yeast Pichia pastoris 3d-em-single electron microscopy 3D single particle reconstruction 3D-EM-single predetermined predetermined participant predetermined Deng Z., He Z., Maksaev G., Bitter RM., Rau M., Fitzpatrick JAJ., Yuan P. yuanp@wustl.edu Accepted 2021-APR-13 AT 17:50 BST AT 17:50 BST by PPORRAS Nature structural & molecular biology 2020 Only protein-protein interactions imex curation imex curation Cryo-EM structures of the ATP release channel pannexin 1. Cryo-EM structures of the ATP release channel pannexin 1. Nature structural & molecular biology 2020 imex curation Deng Z., He Z., Maksaev G., Bitter RM., Rau M., Fitzpatrick JAJ., Yuan P. yuanp@wustl.edu 24-May-2021: Contacted by IntAct-Help. Only protein-protein interactions imex curation picpa Pichia pastoris (Yeast) Yeast Pichia pastoris crosslink cross-linking study crosslink weight by staining molecular weight estimation by staining weight by staining Deng Z., He Z., Maksaev G., Bitter RM., Rau M., Fitzpatrick JAJ., Yuan P. Cross-linking agents: DSS (disuccinimidyl suberate 250 μM) yuanp@wustl.edu Accepted 2021-APR-13 AT 17:50 BST AT 17:50 BST by PPORRAS Nature structural & molecular biology 2020 Only protein-protein interactions imex curation imex curation q96rd7-1 Pannexin-1 PANX1 MRS1 UNQ2529/PRO6028 protein protein human Homo sapiens Human MAIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSARDLDMRDGACSVPGVTENLGQSLWEVSESHFKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKSSGQGIDPMLLLTNLGMIKMDVVDGKTPMSAEMREEQGNQTAELQGMNIDSETKANNGEKNARQRLLDSSC 368B48E0709424FB b3dla5_xentr Pannexin panx1 LOC100170473 PANX protein protein xentr Xenopus tropicalis (Western clawed frog) Silurana tropicalis MAIAHIATEYVFSDFLLKDPPESKYKGLRLELAVDKLVSCIAVGLPLLLISLAFAQEITLGSQISCFAPTSFSWRQAAYVDSFCWAAVQQKHLSQSDSGNVPLWLHKFFPYILLLVAVLLYLPNLFWRFTAAPHLSSDLKFVMEELDKCYNRDIKDIKAANNLNSSDKRDGLNSPVVSENLQQSLWEIPLSHYKYPIVEQYLKTKNNSYGLIIKYLICRVVTLIIVFTACIYLGYYISLFSLTDEFTCNIRTGILRNDTALPPLVQCKLIAVGVFRLLSYINLIIYVLIMPFIIYAMLVPFRKTANVLKVYEVLPTFSVQQAPSKTYDDHSLFLLFLEENVSELKSYKFLKVLENIKNTGENFDTIQYLTSLGTVKTDTVDGKLAFKCTSEVPNNTEQNEVELTVQPSSDNAKTEEKKVRQRLLDSSC 292927382E07491F panx1-3 1 4 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified picpa Pichia pastoris (Yeast) Yeast Pichia pastoris direct interaction direct interaction Fig. 1, Table 1 panx1-5 1 3 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified picpa Pichia pastoris (Yeast) Yeast Pichia pastoris direct interaction direct interaction Fig. 4, Table 1 panx1-4 2 4 weight by staining molecular weight estimation by staining weight by staining experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified picpa Pichia pastoris (Yeast) Yeast Pichia pastoris direct interaction direct interaction Extended Data Fig. 5a panx1-7 2 3 weight by staining molecular weight estimation by staining weight by staining experimental particp experimental participant identification experimental particp unspecified role unspecified role neutral component neutral component purified purified picpa Pichia pastoris (Yeast) Yeast Pichia pastoris direct interaction direct interaction Extended Data Fig. 5a