MINT MINT, Dpt of Biology, University of Rome Tor Vergata MINT http://mint.bio.uniroma2.it/mint url>http://mint.bio.uniroma2.it/mint/ https://mint.bio.uniroma2.it MINT-[0-9]+ https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac} The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules. http://mint.bio.uniroma2.it A Drosophila model of the neurodegenerative disease SCA17 reveals a role of RBP-J/Su(H) in modulating the pathological outcome. A Drosophila model of the neurodegenerative disease SCA17 reveals a role of RBP-J/Su(H) in modulating the pathological outcome. Human molecular genetics 2011 imex curation Ren J., Jegga AG., Zhang M., Deng J., Liu J., Gordon CB., Aronow BJ., Lu LJ., Zhang B., Ma J. Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases. jun.ma@cchmc.org 24-May-2021: Contacted by IntAct-Help. Only protein-protein interactions imex curation drome-head Drosophila melanogaster head anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Ren J., Jegga AG., Zhang M., Deng J., Liu J., Gordon CB., Aronow BJ., Lu LJ., Zhang B., Ma J. Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases. jun.ma@cchmc.org Accepted 2021-APR-12 AT 08:34 BST AT 08:34 BST by MGT Human molecular genetics 2011 Only protein-protein interactions imex curation imex curation tbp_human TATA-box-binding protein TBP TF2D TFIID GTF2D1 TATA-box factor TATA-binding factor TATA sequence-binding protein Transcription initiation factor TFIID TBP subunit protein protein human Homo sapiens Human MDQNNSLPPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHSQTLTTAPLPGTTPLYPSPMTPMTPITPATPASESSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRKTT DIP protein P20226 original sequence version: 106 DIP protein P20226 original sequence version: 157 DIP protein P20226 original sequence version: 173 DIP protein P20226 original sequence version: 194 DIP protein P20226 original sequence version: 179 DIP protein P20226 original sequence version: 131 A61A578D972B970B suh_drome Suppressor of hairless protein Su(H) dRBP-JK J kappa-recombination signal-binding protein RBP-J kappa CG3497 protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MKSYSQFNLNAAAPPAIAYETTVVNPNGSPLDPHQQQQQQSQDMPHFGLPGPQPPSSQQQQQQLQVHHQQQQQQQQQQQQQQHQQQMQMSLLPGPYRPHIEEKKLTRDAMEKYMRERNDMVIVILHAKVAQKSYGNEKRFFCPPPCIYLFGSGWRRRYEEMLQQGEGEQGAQLCAFIGIGSSDQDMQQLDLNGKQYCAAKTLFISDSDKRKHFMLSVKMFYGNGHDIGVFNSKRIKVISKPSKKKQSLKNADLCIASGTNVALFNRLRSQTVSTRYLHVENGHFHASSTQWGAFTIHLLDDNESESEEFQVRDGYIHYGATVKLVCSVTGMALPRLIIRKVDKQMALLEADDPVSQLHKCAFYMKDTDRMYLCLSQEKIIQFQATPCPKEPNKEMINDGACWTIISTDKAEYQFYEGMGPVASPVTPVPIVNSLNLNGGGDVAMLELSGDNFTPHLQVWFGDVEAETMYRCTETLLCVVPEISQFRGEWLWVRQPTQVPISLVRNDGIIYATGLTFTYTPEPGPRPHCNTQAEDVMRARQNNNNNNITSISNNNNSNNAGSPAAGGGLQQQQQQHQALPSISEVQWNSHGSGLS DIP protein P28159 original sequence version: 142 145144F336CD8F4C su(h)-tbp-1 1 3 unspecified role unspecified role prey prey cell lysate cell lysate physiological level physiological level endogenous level endogenous endogenous endogenous level 2 unspecified role unspecified role bait bait cell lysate cell lysate engineered engineered P20226:p.Gln58[80] q80 poly-glutamine extension mutation mutation range range range range QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ QQQQQQQQQQQQQQQQQQQQQQQQQ QQQQQQQQQQQQQQQQQQQQQQQQQ QQQQQQQQQQQQQQQQQQQQQQQQQ QQQQQ physical association physical association fig 4i su(h)-1 1 3 unspecified role unspecified role bait bait cell lysate cell lysate physiological level physiological level endogenous level endogenous endogenous endogenous level 2 unspecified role unspecified role prey prey cell lysate cell lysate engineered engineered P20226:p.Gln58[80] q80 poly-glutamine extension mutation increasing mutation increasing interaction mutation increasing range range range range QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ QQQQQQQQQQQQQQQQQQQQQQQQQ QQQQQQQQQQQQQQQQQQQQQQQQQ QQQQQQQQQQQQQQQQQQQQQQQQQ QQQQQ P20226:p.Gln89_Gln95del q34 poly-glutamine extension mutation mutation certain certain sequence position certain certain certain sequence position certain QQQQQQQ . physical association physical association fig 4j