IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ Protein-protein interaction network and potential drug target candidates of Streptococcus suis. Protein-protein interaction network and potential drug target candidates of Streptococcus suis. Journal of applied microbiology 2020 imex curation Tan MF., Zou G., Wei Y., Liu WQ., Li HQ., Hu Q., Zhang LS., Zhou R. 2020-11-12: Submitted by G Zou, Huazhong Agricultural University College of Veterinary Medicine, Wuhan, China. Files and correspondence for this submission can be found in this tracker ticket: https://helpdesk.ebi.ac.uk/Ticket/Display.html?id=460181&results=26b5ae218fa4bdd0f3456061b60e759e Identifiers for the proteins described in this entry were provided by the authors as part of their data submission. Interactions listed in the original paer, but for which no identifiers were provided could not be curated. rzhou@mail.hzau.edu.cn 05-Jan-2021: Contacted by IntAct-Help. Only protein-protein interactions imex curation ecoli-xl1 Escherichia coli K12 strain ecoli-xl1 Escherichia coli XL-1 strain 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Tan MF., Zou G., Wei Y., Liu WQ., Li HQ., Hu Q., Zhang LS., Zhou R. 2020-11-12: Submitted by G Zou, Huazhong Agricultural University College of Veterinary Medicine, Wuhan, China. Files and correspondence for this submission can be found in this tracker ticket: https://helpdesk.ebi.ac.uk/Ticket/Display.html?id=460181&results=26b5ae218fa4bdd0f3456061b60e759e Identifiers for the proteins described in this entry were provided by the authors as part of their data submission. Interactions listed in the original paer, but for which no identifiers were provided could not be curated. rzhou@mail.hzau.edu.cn Accepted 2020-DEC-14 AT 10:00 GMT AT 10:00 GMT by KALPANAP Journal of applied microbiology 2020 Only protein-protein interactions imex curation imex curation rs5_strsy 30S ribosomal protein S5 rpsE SSU05_0087 protein protein Streptococcus suis (strain 05ZYH33) Streptococcus suis (strain 05ZYH33) MAFKDNAVEIEERVVAINRVTKVVKGGRRLRFAALVVVGDRNGRVGFGTGKAQEVPEAIRKAVESAKKNMIEVPMVGTTIPHEVRSEFGGARVLLKPASEGSGVAAGGATRAVIELAGIADVTSKSLGSNTPINIVRATVEGLKQLKRAEEVAALRGISVSDLA 6E3A6CC42BE184EF a4vui2_strsy SSU05_0805 protein protein Streptococcus suis (strain 05ZYH33) Streptococcus suis (strain 05ZYH33) MKKPIIEFKNVSKVFEDSGTTVLKDISFELEEGKFYTLLGASGSGKSTILNIIAGLLDASSGDIYLDGQRINDVPTNKRDVHTVFQSYALFPHMTVFENVAFPLKLRKIDKAEIERRVTEALQMVRLSGYENRSIQKLSGGQRQRVAIARAIINQPRVVLLDEPLSALDLKLRTEMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNEGEIVQSGTPVDIYDEPINHFVATFIGESNILPGRMIEDYLVEFNGKRFEAVDGGMRPNEEVEVVIRPEDLQITLPEEGKLQVKVDTQLFRGVHYEIIAYDDLGNEWMIHSTRKAIVGEVIGLSFEPEDIHIMRLNETEEEFDARIEEYVEVEEVEDGLINAIEEERNEENL 55DFC7912941A21A a4vvc9_strsy SSU05_1102 protein protein Streptococcus suis (strain 05ZYH33) Streptococcus suis (strain 05ZYH33) MNAISLLFQRSNIALSTKDVHVYYGKNEAIKGIDMQFEKNKITALIGPSGCGKSTYLRSLNRMNDTIDIAKVTGQILYEGIDINRPDMNVYEIRKHIGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLKQAALWDQVKDDLHKSAFTLSGGQQQRLCIARAISVKPQILLMDEPASALDPIATMQLEETMFELKKDYTIIIVTHNMQQAARASDYTAFFYLGDLIEYDKTANVFQNAKLKSTSDYVSGHFG 930C76A117B8E2CC dnak_strsy Chaperone protein DnaK dnaK HSP70 Heat shock 70 kDa protein Heat shock protein 70 SSU05_0300 protein protein Streptococcus suis (strain 05ZYH33) Streptococcus suis (strain 05ZYH33) MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKNGEIIVGDAAKRQAVTNPDTIISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAEEYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDKDEKILVFDLGGGTFDVSILELGDGVFDVLATAGDNKLGGDDFDQKIIDHMVAEFKKENGIDLSADKMALQRLKDAAEKAKKDLSGVTSTQISLPFITAGAAGPLHLEMTLTRAKFDELTYDLVERTKIPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKSVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSKSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDKNGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNDVDQAIFATEKTLKETEGKGFDAERDQAQAALDELKAAQEANNLDDMKAKLENLNEKAQALAVKLYEQAAAAQQAAAGQEGAQTANNADDDVVDGEFTEK EC6F94A95ADC38BE efg_strsy Elongation factor G fusA SSU05_0152 protein protein Streptococcus suis (strain 05ZYH33) Streptococcus suis (strain 05ZYH33) MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETHEGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGAVTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHERLQANAHPIQLPIGSEDEFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLEQAEEYREKLVEAVAETDEELMMKYLEGEEITNDELKAAIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIDYLPSPLDIPAIKGVNPDTDAEEERHASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVLNSGSYVLNTSKGKRERIGRILQMHANSRQEIETVYAGDIAAAVGLKDTTTGDSLTDEKAKIILESIHVPEPVIQLMVEPKSKADQDKMGIALSKLAEEDPTFRVETNVETGETVISGMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDVWIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPIVDVKAKLYDGSYHDVDSSETAFKVAASLALKEAAKSAQPTILEPMMLVTITAPEDNLGDVMGHVTARRGRVDGMEARGNTQIVRAYVPLAEMFGYATVLRSATQGRGTFMMVFDHYEDVPKSVQDEIIKKNGGNA 0845C751E04FD0B8 a4vw38_strsy SSU05_1361 protein protein Streptococcus suis (strain 05ZYH33) Streptococcus suis (strain 05ZYH33) MALVEFKDVNKYYGDYHALRNINLEFEPGQVVVLLGPSGSGKSTLIRTINGLEAIDEGTLIVNGHDISSTSIKELVSLRKEVGMVFQHFNLYPHKTVLENVTLAPIKVLGINKATAEKTAQKYLEFVNLWDRKDSYPAMLSGGQKQRVAIARGLAMKPELLLFDEPTSALDPETIGDVLAVMQKLARDGMNMIVVTHEMGFAREVADRIIFMAEGEVLVDTTDVNGFFDNPTEPRAQQFLSKIINHESDKVKL FD9018CD4FB047B4 rs2_strsy 30S ribosomal protein S2 rpsB SSU05_1980 protein protein Streptococcus suis (strain 05ZYH33) Streptococcus suis (strain 05ZYH33) MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQQTVKLADQAYEFIRDAAANEAVILFVGTKKQAAEAVKDEAIRAGQYFINHRWLGGTLTNWGTIQKRIARLKEINRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIADMPRIPDVMFVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKMADAIIEGNQGEDSVAAVEAELAAEPASTESIEELVEVVEGK DD76949EEE296843 a4vse7_strsy Protein RecA recA Recombinase A SSU05_0064 protein protein Streptococcus suis (strain 05ZYH33) Streptococcus suis (strain 05ZYH33) MRLEQVAILKGRIIEIYGPESSGKTTVALHAVAQAQKDGGIAAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVAALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTVAIFINQLREKVGVMFGNPETTPGGRALKFYASVRMDVRGNTQIKGTGDKKDQNVGKETKVKIVKNKVAPPFKEAVVEIMYGEGISRTGELIEIGSNLGIIQKAGAWYSYNGEKIGQGSENAKKFLADNPAIFDEIDRKIRVHYGLIEADGVEEVATEEAPVVAEEIQDVILDLDGGIELED 105D304C6861AD85 a4vxn4_strsy SSU05_1907 protein protein Streptococcus suis (strain 05ZYH33) Streptococcus suis (strain 05ZYH33) MNMVQLNLKNIYKKYPNSEHYSVEDFNLDIKDKEFIVFVGPSGCGKSTTLRMIAGLEDITEGEAYIDGVLMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGLKLRKYSKDEIKKRVEEAAQILGLTEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMDEPLSNLDAKLRVSMRTEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGTGTIGRIEQIGSPEELYNRPVNKFVASFIGSPAMNFFTVTLQDGVLVGDGFKVELPEGRRKHLEEKGYNGKSFTLGIRPEDIKASQLELDTYPSSIVEAEVVVSELLGAETMLYSKVGSTEFVSRVDARDYHNPGDKVRLTFNLNKAHFFDDETSKAIV 3E54931F81ADE58D a4vtk8_strsy Cell division protein FtsZ ftsZ SSU05_0481 protein protein Streptococcus suis (strain 05ZYH33) Streptococcus suis (strain 05ZYH33) MAFSFEAAASHGAVIKVIGVGGGGGNAINRMIEEGVAGVEFIAANTDVQALSSSKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEEALTNVLTGADMVFITAGMGGGSGTGAAPVIARIAKNLGALTVAVVTRPFGFEGNKRGNFAIEGIEGLREQVDTLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTVMENKGNALMGIGIGTGEDRVIEAARKAIYSPLLETTIDGAEDVIVNVTGGYDMTLTEAEDASEIVNQAAGQGVNIWLGTSIDETMKDEIRVTVVATGVRQDTADKPARHRTEAVSPRPSHRFDHSVASAPTRGAAQQTEAPKASAFGEWDLRRENLIRPTDTEPTSTVSVEKFTMDQDEDELDTPPFFRNR B85E16F123777718 a4vva2_strsy DNA gyrase subunit A gyrA SSU05_1075 protein protein Streptococcus suis (strain 05ZYH33) Streptococcus suis (strain 05ZYH33) MQDKNLVTVNLTNEMKSSFIDYAMSVIVSRALPDVRDGLKPVHRRILYGMNELGITPDKPHKKSARITGDVMGKYHPHGDSAIYEAMVRMAQWWSYRHMLVDGHGNFGSMDGDGAAAQRYTEARMSKIALEMLRDINKNTVNFADNYDASEREPEVLPARFPNLLVNGTTGIAVGMATNIPPHNLGETIEAVKLVMDNPEVTTREIMEVLPGPDFPTGALVMGKSGIHRAYETGKGSIVLRSRTEIEEYGNGRERIVVTEFPYMVNKSKVQEHIVKLVQEKRIEGITAVRDESNREGVRFVIEVRRDASANVILNNLFKQTQLQTNFSFNMLAIQNGVPKILSVRQILESYIEHQKEVVTRRTRFDKEKAEARAHILEGLLIALDHIDEVIRIIRNSETDAIAQAELMEKFDLSERQSQAILDMRLRRLTGLERDKIQSEYDELVALIADLADILAKPERVVQIIKDELEEVKRKYADPRRTELMVGEVLSLEDEDLIEETDVLITLSNQGYIKRLAQDEFQAQKRGGRGVQGTGVKDDDFVRELVSTSTHDRLLFFTNKGRVYRLKGYEIPEYGRTAKGLPVVNLLKLEENEAIQTIINVTKDQEADSYLFFATRQGVVKRTSVSEFANIRQSGLKALNLKEDDELINVFLTNGQADIIMGTKFGYSVRFTETDVRNMGRTATGVRGINLREGDQLVGATMISDDQEVLVLTEKGFGKRTPASEYPTKGRGGKGIKTLKVADKNGSLAGLTTVSGDEDIMVITDTGVIIRTSVANISQTGRSTMGVKVMRLNGEAKIMTFALVDAAEIKEEKE 0DDAA42DE2E57101 a4vtm3_strsy SSU05_0496 protein protein Streptococcus suis (strain 05ZYH33) Streptococcus suis (strain 05ZYH33) MSNAIISIKDLHKYFGKNEVLKGIDLDIQQGQVVVIIGPSGSGKSTFLRTMNLLEVPTKGTVTFEGVDITDKSNDIFKMREKMGMVFQQFNLFPNMTVLDNITLSPIKTKGIAKDEAEKKAKELLEKVGLPDKANAYPQSLSGGQQQRIAIARGLAMDPDVLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMDGGVIVEDGTPEEVFEHTKEERTKDFLSKVL 75524EF111B9B515 rl5_strsy 50S ribosomal protein L5 rplE SSU05_0083 protein protein Streptococcus suis (strain 05ZYH33) Streptococcus suis (strain 05ZYH33) MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGDAVSNAKNLEKAAQELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLDKLVTVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGMDIVIVTTANTDEESRALLTGLGMPFAK 2899A59FFB0EB976 seca_strsy Protein translocase subunit SecA secA SSU05_1814 protein protein Streptococcus suis (strain 05ZYH33) Streptococcus suis (strain 05ZYH33) MKCMVTNVLRSLIENDKGELRKLEKMADKVFSYADEMEALTDEQLQAKTAEFKERYNNGESLDDLLYEAYAVVREGARRVLGLYPYKVQVMGGIVLHNGDVPEMRTGEGKTLTATMPVYLNALSGQGVHVVTVNEYLSTRDATEMGELYSWLGLSVGINLAAKSPLEKREAYNCDITYSTNSEIGFDYLRDNMVVRAEDMVQRPLNYALVDEVDSILIDEARTPLIVSGAQGSETNQLYFLADNLVKSLTTEDYIIDIPSKTIGLSDSGIDKAEKFFKLDNLYDIENVAITHFLDNALRANYIMTYDIDYLVNEDQEVMIIDPFTGRTMEGRRYSDGLHQAIEAKEGVPVQNESKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVVPIPTNRPIARVDHEDLLYPSLEYKFNAVIADVKRRYEKGQPVLVGTVAVETSDLISQKLVAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGPGVRELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERIKVFMERMNLTEEESVIKSKMLTRQVESAQKRVEGNNYDSRKQVLQYDDVMREQREIIYRQRQDVITADRDLAPEIKAMMKRTIERQVAGHFLGSKDEAIDGIIKFAHANLVEDDTLSKATFEAMNQKEIVEELYERALRVYDSQVKKLRDEERVREFQKVLILRVVDNKWTDHIDALDQLRNAVSLRGYAQNNPIVEYQSEAFTMFNDMIGAIEFEVTRLMMKAQIHDNIERERTSQEAHTTAVKNIMPNQSHAIQENVSFEGVDRNDPCPCQSGKKFKNCHGRK 6E03C9ED4E3C53F8 ftsz-reca-1 1 recA 9 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed ftsZ 11 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed physical association physical association 4B ftsz-reca-2 1 rplE 14 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed ftsZ 11 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed physical association physical association 4B ftsz-rpse-1 1 rpsE 2 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed ftsZ 11 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed physical association physical association 4B ftsz-fusa-1 1 fus 6 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed ftsZ 11 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed physical association physical association 4B ftsz-dnak-1 1 dnaK 5 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed ftsZ 11 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed physical association physical association 4B ftsz-dnak-2 1 ftsZ 11 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed ftsZ 11 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed physical association physical association 4B ftsz-a4vtm3_strsy-1 1 glnQ3 13 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed ftsZ 11 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed physical association physical association 4B ftsz-pota-1 1 gyrA 12 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed ftsZ 11 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed physical association physical association 4B ftsz-pstb-1 1 pstB2 4 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed ftsZ 11 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed physical association physical association 4B ftsz-a4vw38_strsy-1 1 glnQ4 7 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed ftsZ 11 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed physical association physical association 4B ftsz-seca-1 1 msmK 10 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed ftsZ 11 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed physical association physical association 4B ftsz-rpsb-1 1 rpsB 8 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed ftsZ 11 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed physical association physical association 4B ftsz-seca-2 1 secA 15 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed ftsZ 11 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed physical association physical association 4B ftsz-pota-2 1 potA 3 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed ftsZ 11 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed physical association physical association 4B