<?xml version='1.0' encoding='UTF-8'?>
<entrySet xmlns="http://psi.hupo.org/mi/mif300" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://psi.hupo.org/mi/mif300 https://raw.githubusercontent.com/HUPO-PSI/miXML/master/3.0/src/MIF300.xsd" level="3" version="0" minorVersion="0">
  <entry>
    <source releaseDate="2022-02-04">
      <names>
        <shortLabel>DIP</shortLabel>
        <fullName>Database of Interacting Proteins</fullName>
      </names>
      <xref>
        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="identity" refTypeAc="MI:0356"/>
        <secondaryRef db="pubmed" dbAc="MI:0446" id="14681454" refType="identity" refTypeAc="MI:0356"/>
        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1579232" refType="identity" refTypeAc="MI:0356"/>
      </xref>
      <attributeList>
        <attribute name="postaladdress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
        <attribute name="url" nameAc="MI:0614">http://dip.doe-mbi.ucla.edu/</attribute>
        <attribute name="contact-email" nameAc="MI:0634">dip@mbi.ucla.edu</attribute>
      </attributeList>
    </source>
    <experimentList>
      <experimentDescription id="1">
        <names>
          <fullName>Crystal structure of the tubulin tyrosine carboxypeptidase complex VASH1-SVBP.</fullName>
        </names>
        <bibref>
          <xref>
            <primaryRef db="pubmed" dbAc="MI:0446" id="31270470" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-21497535" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="imex" dbAc="MI:0670" id="IM-28327" refType="imex-primary" refTypeAc="MI:0662"/>
          </xref>
          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">Crystal structure of the tubulin tyrosine carboxypeptidase complex VASH1-SVBP.</attribute>
            <attribute name="journal" nameAc="MI:0885">Nature structural &amp; molecular biology</attribute>
            <attribute name="publication year" nameAc="MI:0886">2019</attribute>
            <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
            <attribute name="author-list" nameAc="MI:0636">Adamopoulos A., Landskron L., Heidebrecht T., Tsakou F., Bleijerveld OB., Altelaar M., Nieuwenhuis J., Celie PHN., Brummelkamp TR., Perrakis A.</attribute>
            <attribute name="contact-email" nameAc="MI:0634">a.perrakis@nki.nl</attribute>
            <attribute name="author-announcement">13-Nov-2020: Contacted by IntAct-Help.</attribute>
            <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
            <attribute name="imex curation" nameAc="MI:0959">imex curation</attribute>
          </attributeList>
        </bibref>
        <xref>
          <primaryRef db="pubmed" dbAc="MI:0446" id="31270470" refType="primary-reference" refTypeAc="MI:0358"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-28327" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <hostOrganismList>
          <hostOrganism ncbiTaxId="7108">
            <names>
              <shortLabel>spofr-sf_9</shortLabel>
              <fullName>Spodoptera frugiperda insect cells</fullName>
              <alias type="synonym" typeAc="MI:1041">Fall armyworm</alias>
            </names>
            <cellType>
              <names>
                <shortLabel>sf_9</shortLabel>
                <fullName>insect cells</fullName>
              </names>
              <xref>
                <primaryRef db="cabri" dbAc="MI:0246" id="ACC 125" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="IA:0078" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="mint" dbAc="MI:0471" id="MINT-86941" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-346407" refType="identity" refTypeAc="MI:0356"/>
              </xref>
              <attributeList>
                <attribute name="comment" nameAc="MI:0612">Derived from pupal ovarian tissue of the fall armyworm</attribute>
                <attribute name="comment" nameAc="MI:0612">Cloned from the parent cell line, IPLB-SF-21-AE (SF-21)</attribute>
                <attribute name="comment" nameAc="MI:0612">derived from immature ovaries of fall armyworm Spodoptera frugiperda pupae</attribute>
                <attribute name="comment" nameAc="MI:0612">cells are susceptible to Baculovirus infection</attribute>
              </attributeList>
            </cellType>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>x-ray diffraction</shortLabel>
            <fullName>x-ray crystallography</fullName>
            <alias type="go synonym" typeAc="MI:0303">X-ray</alias>
            <alias type="synonym" typeAc="MI:1041">X-ray</alias>
            <alias type="synonym" typeAc="MI:1041">x-ray diffraction</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0114" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1272" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>predetermined</shortLabel>
            <fullName>predetermined participant</fullName>
            <alias type="synonym" typeAc="MI:1041">predetermined</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Adamopoulos A., Landskron L., Heidebrecht T., Tsakou F., Bleijerveld OB., Altelaar M., Nieuwenhuis J., Celie PHN., Brummelkamp TR., Perrakis A.</attribute>
          <attribute name="contact-email" nameAc="MI:0634">a.perrakis@nki.nl</attribute>
          <attribute name="accepted">Accepted 2020-OCT-05 AT 09:00 BST AT 09:00 BST by LIVIAP</attribute>
          <attribute name="journal" nameAc="MI:0885">Nature structural &amp; molecular biology</attribute>
          <attribute name="publication year" nameAc="MI:0886">2019</attribute>
          <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
          <attribute name="imex curation" nameAc="MI:0959">imex curation</attribute>
          <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
        </attributeList>
      </experimentDescription>
    </experimentList>
    <interactorList>
      <interactor id="2">
        <names>
          <shortLabel>q7l8a9-1</shortLabel>
          <fullName>Tubulinyl-Tyr carboxypeptidase 1</fullName>
          <alias type="gene name" typeAc="MI:0301">VASH1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">KIAA1036</alias>
          <alias type="gene name synonym" typeAc="MI:0302">VASH</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Tubulin carboxypeptidase 1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Tyrosine carboxypeptidase 1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Vasohibin-1</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q7L8A9-1" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000167106" version="SP_130" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-21497569" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000071246" version="SP_130" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000167106" version="SP_130" refType="transcript"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-10256546" refType="isoform-parent" refTypeAc="MI:0243"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MPGGKKVAGGGSSGATPTSAAATAPSGVRRLETSEGTSAQRDEEPEEEGEEDLRDGGVPFFVNRGGLPVDEATWERMWKHVAKIHPDGEKVAQRIRGATDLPKIPIPSVPTFQPSTPVPERLEAVQRYIRELQYNHTGTQFFEIKKSRPLTGLMDLAKEMTKEALPIKCLEAVILGIYLTNSMPTLERFPISFKTYFSGNYFRHIVLGVNFAGRYGALGMSRREDLMYKPPAFRTLSELVLDFEAAYGRCWHVLKKVKLGQSVSHDPHSVEQIEWKHSVLDVERLGRDDFRKELERHARDMRLKIGKGTGPPSPTKDRKKDVSSPQRAQSSPHRRNSRSERRPSGDKKTSEPKAMPDLNGYQIRV</sequence>
        <attributeList>
          <attribute name="crc64">CEE39875FA9DA70B</attribute>
        </attributeList>
      </interactor>
      <interactor id="3">
        <names>
          <shortLabel>svbp_human</shortLabel>
          <fullName>Small vasohibin-binding protein</fullName>
          <alias type="gene name" typeAc="MI:0301">SVBP</alias>
          <alias type="gene name synonym" typeAc="MI:0302">CCDC23</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Coiled coil domain-containing protein 23</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q8N300" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A8K5P1" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="D3DPW7" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000361599" version="SP_121" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000361600" version="SP_121" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-21497577" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_955374.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016856715.1"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0061564" version="SP_121"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1905048" version="SP_121"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR031378" version="SP_121"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6J4O" version="SP_121"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6J4P" version="SP_121"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6J4Q" version="SP_121"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6J4S" version="SP_121"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6J4U" version="SP_121"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6J4V" version="SP_121"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6J7B" version="SP_121"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6J8F" version="SP_121"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6J8N" version="SP_121"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6J8O" version="SP_121"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6J91" version="SP_121"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6J9H" version="SP_121"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6JZC" version="SP_121"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6JZD" version="SP_121"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6JZE" version="SP_121"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6K81" version="SP_121"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6LPG" version="SP_121"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045177" version="SP_121"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6NVQ" version="SP_121"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6OCF" version="SP_121"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6OCG" version="SP_121"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000177868" version="SP_121" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000372521" version="SP_121" refType="transcript"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000372522" version="SP_121" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005576" version="SP_121"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" version="SP_121"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005856" version="SP_121"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006508" version="SP_121"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008017" version="SP_121"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0009306" version="SP_121"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0010596" version="SP_121"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0031397" version="SP_121"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6QBY" version="SP_121"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6WSL" version="SP_121"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8955332" version="SP_121"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6OCH" version="SP_121"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MDPPARKEKTKVKESVSRVEKAKQKSAQQELKQRQRAEIYALNRVMTELEQQQFDEFCKQMQPPGE</sequence>
        <attributeList>
          <attribute name="crc64">9B128ABBF6ECD858</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="4" imexId="IM-28327-1">
        <names>
          <shortLabel>svbp-vash1-1</shortLabel>
        </names>
        <xref>
          <primaryRef db="wwpdb" dbAc="MI:0805" id="6NVQ" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-21497607" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-28327-1" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="5">
            <interactorRef>2</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>structure determination</shortLabel>
                  <fullName>identification by structure determination</fullName>
                  <alias type="synonym" typeAc="MI:1041">identification by structure determination</alias>
                  <alias type="synonym" typeAc="MI:1041">structure determination</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:2287" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-20597534" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="7877166" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>experimental particp</shortLabel>
                  <fullName>experimental participant identification</fullName>
                  <alias type="synonym" typeAc="MI:1041">experimental particp</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0661" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-933978" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>purified</shortLabel>
                  <fullName>purified</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
            <featureList>
              <feature id="6">
                <names>
                  <shortLabel>Q7L8A9-1:p.Cys169Ala</shortLabel>
                  <fullName>C169A mutation</fullName>
                </names>
                <xref>
                  <primaryRef db="intact" dbAc="MI:0469" id="EBI-21497616" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>mutation</shortLabel>
                    <fullName>mutation</fullName>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0118" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456558" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <begin position="169"/>
                    <endStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                    <end position="169"/>
                    <resultingSequence>
                      <originalSequence>C</originalSequence>
                      <newSequence>A</newSequence>
                    </resultingSequence>
                  </featureRange>
                </featureRangeList>
                <attributeList>
                  <attribute name="remark-internal">Tue Jun 30 19:06:04 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Cys169Ala'</attribute>
                </attributeList>
              </feature>
              <feature id="7">
                <names>
                  <shortLabel>1-315 binding region</shortLabel>
                  <fullName>1-315 binding region</fullName>
                </names>
                <xref>
                  <primaryRef db="intact" dbAc="MI:0469" id="EBI-21497614" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>binding region</shortLabel>
                    <fullName>binding-associated region</fullName>
                    <alias type="synonym" typeAc="MI:1041">binding region</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0117" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456493" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <begin position="1"/>
                    <endStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                    <end position="315"/>
                  </featureRange>
                </featureRangeList>
              </feature>
            </featureList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="7108">
                <names>
                  <shortLabel>spofr-sf_9</shortLabel>
                  <fullName>Spodoptera frugiperda insect cells</fullName>
                  <alias type="synonym" typeAc="MI:1041">Fall armyworm</alias>
                </names>
                <cellType>
                  <names>
                    <shortLabel>sf_9</shortLabel>
                    <fullName>insect cells</fullName>
                  </names>
                  <xref>
                    <primaryRef db="cabri" dbAc="MI:0246" id="ACC 125" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="IA:0078" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="MINT-86941" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-346407" refType="identity" refTypeAc="MI:0356"/>
                  </xref>
                  <attributeList>
                    <attribute name="comment" nameAc="MI:0612">Derived from pupal ovarian tissue of the fall armyworm</attribute>
                    <attribute name="comment" nameAc="MI:0612">Cloned from the parent cell line, IPLB-SF-21-AE (SF-21)</attribute>
                    <attribute name="comment" nameAc="MI:0612">derived from immature ovaries of fall armyworm Spodoptera frugiperda pupae</attribute>
                    <attribute name="comment" nameAc="MI:0612">cells are susceptible to Baculovirus infection</attribute>
                  </attributeList>
                </cellType>
              </hostOrganism>
            </hostOrganismList>
            <stoichiometry value="1"/>
          </participant>
          <participant id="8">
            <interactorRef>3</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>structure determination</shortLabel>
                  <fullName>identification by structure determination</fullName>
                  <alias type="synonym" typeAc="MI:1041">identification by structure determination</alias>
                  <alias type="synonym" typeAc="MI:1041">structure determination</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:2287" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-20597534" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="7877166" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>experimental particp</shortLabel>
                  <fullName>experimental participant identification</fullName>
                  <alias type="synonym" typeAc="MI:1041">experimental particp</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0661" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-933978" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>purified</shortLabel>
                  <fullName>purified</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="7108">
                <names>
                  <shortLabel>spofr-sf_9</shortLabel>
                  <fullName>Spodoptera frugiperda insect cells</fullName>
                  <alias type="synonym" typeAc="MI:1041">Fall armyworm</alias>
                </names>
                <cellType>
                  <names>
                    <shortLabel>sf_9</shortLabel>
                    <fullName>insect cells</fullName>
                  </names>
                  <xref>
                    <primaryRef db="cabri" dbAc="MI:0246" id="ACC 125" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="IA:0078" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="MINT-86941" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-346407" refType="identity" refTypeAc="MI:0356"/>
                  </xref>
                  <attributeList>
                    <attribute name="comment" nameAc="MI:0612">Derived from pupal ovarian tissue of the fall armyworm</attribute>
                    <attribute name="comment" nameAc="MI:0612">Cloned from the parent cell line, IPLB-SF-21-AE (SF-21)</attribute>
                    <attribute name="comment" nameAc="MI:0612">derived from immature ovaries of fall armyworm Spodoptera frugiperda pupae</attribute>
                    <attribute name="comment" nameAc="MI:0612">cells are susceptible to Baculovirus infection</attribute>
                  </attributeList>
                </cellType>
              </hostOrganism>
            </hostOrganismList>
            <stoichiometry value="1"/>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>direct interaction</shortLabel>
            <fullName>direct interaction</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">Fig 1b, Sup Tab 1</attribute>
        </attributeList>
      </interaction>
    </interactionList>
  </entry>
</entrySet>