IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ Cdk-mediated phosphorylation of the Kvβ2 auxiliary subunit regulates Kv1 channel axonal targeting. Cdk-mediated phosphorylation of the Kvβ2 auxiliary subunit regulates Kv1 channel axonal targeting. The Journal of cell biology 2011 imex curation Vacher H., Yang JW., Cerda O., Autillo-Touati A., Dargent B., Trimmer JS. email sent to author to request origin species of: GST-EB1, GFP-EB1 and GST-KvBeta2. the Email address provided in the publication is not correct, so no interaction involving these constructs has been annotated. helene.vacher@univmed.fr 09-May-2019: Contacted by IntAct-Help. Only protein-protein interactions imex curation rat-brain Rattus norvegicus brain brain Brain [cerebrum] anti bait coip anti bait coimmunoprecipitation anti bait coip sequence tag sequence tag identification sequence tag Vacher H., Yang JW., Cerda O., Autillo-Touati A., Dargent B., Trimmer JS. email sent to author to request origin species of: GST-EB1, GFP-EB1 and GST-KvBeta2. the Email address provided in the publication is not correct, so no interaction involving these constructs has been annotated. 1% Triton X-100 extracts of Rat Brain Membranes were used helene.vacher@univmed.fr Accepted 2018-DEC-14 AT 09:42 GMT AT 09:42 GMT by ORCHARD The Journal of cell biology 2011 imex curation Cdk-mediated phosphorylation of the Kvβ2 auxiliary subunit regulates Kv1 channel axonal targeting. Cdk-mediated phosphorylation of the Kvβ2 auxiliary subunit regulates Kv1 channel axonal targeting. The Journal of cell biology 2011 imex curation Vacher H., Yang JW., Cerda O., Autillo-Touati A., Dargent B., Trimmer JS. email sent to author to request origin species of: GST-EB1, GFP-EB1 and GST-KvBeta2. the Email address provided in the publication is not correct, so no interaction involving these constructs has been annotated. helene.vacher@univmed.fr 09-May-2019: Contacted by IntAct-Help. Only protein-protein interactions imex curation human-brain-hippocampus Homo sapiens hippocampus brain_hippocampus brain hippocampus anti bait coip anti bait coimmunoprecipitation anti bait coip sequence tag sequence tag identification sequence tag Vacher H., Yang JW., Cerda O., Autillo-Touati A., Dargent B., Trimmer JS. email sent to author to request origin species of: GST-EB1, GFP-EB1 and GST-KvBeta2. the Email address provided in the publication is not correct, so no interaction involving these constructs has been annotated. 1% Triton X-100 extracts of Human Hippocampal Membranes were used helene.vacher@univmed.fr Accepted 2018-DEC-14 AT 09:42 GMT AT 09:42 GMT by ORCHARD The Journal of cell biology 2011 imex curation Cdk-mediated phosphorylation of the Kvβ2 auxiliary subunit regulates Kv1 channel axonal targeting. Cdk-mediated phosphorylation of the Kvβ2 auxiliary subunit regulates Kv1 channel axonal targeting. The Journal of cell biology 2011 imex curation Vacher H., Yang JW., Cerda O., Autillo-Touati A., Dargent B., Trimmer JS. email sent to author to request origin species of: GST-EB1, GFP-EB1 and GST-KvBeta2. the Email address provided in the publication is not correct, so no interaction involving these constructs has been annotated. helene.vacher@univmed.fr 09-May-2019: Contacted by IntAct-Help. Only protein-protein interactions imex curation mouse-brain Mus musculus brain brain Brain [cerebrum] anti bait coip anti bait coimmunoprecipitation anti bait coip sequence tag sequence tag identification sequence tag Vacher H., Yang JW., Cerda O., Autillo-Touati A., Dargent B., Trimmer JS. email sent to author to request origin species of: GST-EB1, GFP-EB1 and GST-KvBeta2. the Email address provided in the publication is not correct, so no interaction involving these constructs has been annotated. 1% Triton X-100 extracts of Mouse Brain Membranes were used helene.vacher@univmed.fr Accepted 2018-DEC-14 AT 09:42 GMT AT 09:42 GMT by ORCHARD The Journal of cell biology 2011 imex curation kcna2_mouse Potassium voltage-gated channel subfamily A member 2 Voltage-gated potassium channel subunit Kv1.2 Kcna2 MK2 protein protein mouse Mus musculus Mouse MTVATGDPVDEAAALPGHPQDTYDPEADHECCERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGGGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERDSQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQYLQVTSCPKIPSSPDLKKSRSASTISKSDYMEIQEGVNNSNEDFREENLKTANCTLANTNYVNITKMLTDV DIP protein P63141 original sequence version: 55 A8FEA6F3F59AF42A kcab2_mouse Voltage-gated potassium channel subunit beta-2 K(+) channel subunit beta-2 Kv-beta-2 Neuroimmune protein F5 Kcnab2 Ckbeta2 I2rf5 Kcnb3 protein protein mouse Mus musculus Mouse MYPESTTGSPARLSLRQTGSPGMIYSTRYGSPKRQLQFYRNLGKSGLRVSCLGLGTWVTFGGQITDEMAEHLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRPDPNTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLIPPICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSGIPPYSRASLKGYQWLKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASNAEQLMENIGAIQVLPKLSSSIVHEIDSILGNKPYSKKDYRS 5303FD1411B324FC kcna2_human Potassium voltage-gated channel subfamily A member 2 KCNA2 NGK1 Voltage-gated K(+) channel HuKIV Voltage-gated potassium channel HBK5 Voltage-gated potassium channel subunit Kv1.2 protein protein human Homo sapiens Human MTVATGDPADEAAALPGHPQDTYDPEADHECCERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQYLQVTSCPKIPSSPDLKKSRSASTISKSDYMEIQEGVNNSNEDFREENLKTANCTLANTNYVNITKMLTDV 4B03F1B46A826C39 kcab2_human Voltage-gated potassium channel subunit beta-2 K(+) channel subunit beta-2 Kv-beta-2 KCNAB2 KCNA2B KCNK2 protein protein human Homo sapiens Human MYPESTTGSPARLSLRQTGSPGMIYSTRYGSPKRQLQFYRNLGKSGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRPDPNTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTPPICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSGIPPYSRASLKGYQWLKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASNADQLMENIGAIQVLPKLSSSIIHEIDSILGNKPYSKKDYRS 91A673F8992140DA kcna2_rat Potassium voltage-gated channel subfamily A member 2 Voltage-gated potassium channel subunit Kv1.2 RBK2 RCK5 RAK Kcna2 protein protein rat Rattus norvegicus (Rat) Rat MTVATGDPVDEAAALPGHPQDTYDPEADHECCERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGGGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERDSQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQYLQVTSCPKIPSSPDLKKSRSASTISKSDYMEIQEGVNNSNEDFREENLKTANCTLANTNYVNITKMLTDV A8FEA6F3F59AF42A kcab2_rat Voltage-gated potassium channel subunit beta-2 K(+) channel subunit beta-2 Kv-beta-2 Kcnab2 Ckbeta2 Kcnb3 protein protein rat Rattus norvegicus (Rat) Rat MYPESTTGSPARLSLRQTGSPGMIYSTRYGSPKRQLQFYRNLGKSGLRVSCLGLGTWVTFGGQITDEMAEHLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRPDPNTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLIPPICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSGIPPYSRASLKGYQWLKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASNAEQLMENIGAIQVLPKLSSSIVHEIDSILGNKPYSKKDYRS 5303FD1411B324FC kvb2-kv12-1 1 8 unspecified role unspecified role bait bait subcellular prep subcellular preparation subcellular prep physiological level physiological level endogenous level endogenous endogenous endogenous level 9 unspecified role unspecified role prey prey subcellular prep subcellular preparation subcellular prep physiological level physiological level endogenous level endogenous endogenous endogenous level phosphorylated Ser opser O-phospho-L-serine (2S)-2-amino-3-(phosphonooxy)propanoic acid 2-amino-3-hydroxypropanoic acid 3-phosphate 2-azanyl-3-(phosphonooxy)propanoic acid ACT_SITE Phosphoserine intermediate MOD_RES Phosphoserine O-phospho-L-serine O-phosphonoserine O-phosphorylated L-serine O3-phosphoserine serine phosphate ester OPSer Phospho Phospho Seryl Phosphorylation phosphorylations sequence tag sequence tag identification certain certain sequence position certain certain certain sequence position certain observed-ptm observed-ptm observed ptm observed-ptm phosphorylated Ser opser O-phospho-L-serine (2S)-2-amino-3-(phosphonooxy)propanoic acid 2-amino-3-hydroxypropanoic acid 3-phosphate 2-azanyl-3-(phosphonooxy)propanoic acid ACT_SITE Phosphoserine intermediate MOD_RES Phosphoserine O-phospho-L-serine O-phosphonoserine O-phosphorylated L-serine O3-phosphoserine serine phosphate ester OPSer Phospho Phospho Seryl Phosphorylation phosphorylations sequence tag sequence tag identification certain certain sequence position certain certain certain sequence position certain observed-ptm observed-ptm observed ptm observed-ptm phosphorylated Ser opser O-phospho-L-serine (2S)-2-amino-3-(phosphonooxy)propanoic acid 2-amino-3-hydroxypropanoic acid 3-phosphate 2-azanyl-3-(phosphonooxy)propanoic acid ACT_SITE Phosphoserine intermediate MOD_RES Phosphoserine O-phospho-L-serine O-phosphonoserine O-phosphorylated L-serine O3-phosphoserine serine phosphate ester OPSer Phospho Phospho Seryl Phosphorylation phosphorylations sequence tag sequence tag identification certain certain sequence position certain certain certain sequence position certain observed-ptm observed-ptm observed ptm observed-ptm phosphorylated Ser opser O-phospho-L-serine (2S)-2-amino-3-(phosphonooxy)propanoic acid 2-amino-3-hydroxypropanoic acid 3-phosphate 2-azanyl-3-(phosphonooxy)propanoic acid ACT_SITE Phosphoserine intermediate MOD_RES Phosphoserine O-phospho-L-serine O-phosphonoserine O-phosphorylated L-serine O3-phosphoserine serine phosphate ester OPSer Phospho Phospho Seryl Phosphorylation phosphorylations sequence tag sequence tag identification certain certain sequence position certain certain certain sequence position certain observed-ptm observed-ptm observed ptm observed-ptm physical association physical association Table 1. Fig.1A kcna2-kcnab2-1 3 4 unspecified role unspecified role bait bait subcellular prep subcellular preparation subcellular prep physiological level physiological level endogenous level endogenous endogenous endogenous level 5 unspecified role unspecified role prey prey subcellular prep subcellular preparation subcellular prep physiological level physiological level endogenous level endogenous endogenous endogenous level phosphorylated Ser opser O-phospho-L-serine (2S)-2-amino-3-(phosphonooxy)propanoic acid 2-amino-3-hydroxypropanoic acid 3-phosphate 2-azanyl-3-(phosphonooxy)propanoic acid ACT_SITE Phosphoserine intermediate MOD_RES Phosphoserine O-phospho-L-serine O-phosphonoserine O-phosphorylated L-serine O3-phosphoserine serine phosphate ester OPSer Phospho Phospho Seryl Phosphorylation phosphorylations sequence tag sequence tag identification certain certain sequence position certain certain certain sequence position certain observed-ptm observed-ptm observed ptm observed-ptm phosphorylated Ser opser O-phospho-L-serine (2S)-2-amino-3-(phosphonooxy)propanoic acid 2-amino-3-hydroxypropanoic acid 3-phosphate 2-azanyl-3-(phosphonooxy)propanoic acid ACT_SITE Phosphoserine intermediate MOD_RES Phosphoserine O-phospho-L-serine O-phosphonoserine O-phosphorylated L-serine O3-phosphoserine serine phosphate ester OPSer Phospho Phospho Seryl Phosphorylation phosphorylations sequence tag sequence tag identification certain certain sequence position certain certain certain sequence position certain observed-ptm observed-ptm observed ptm observed-ptm physical association physical association Table 1 kcna2-kcnab2-2 2 6 unspecified role unspecified role bait bait subcellular prep subcellular preparation subcellular prep physiological level physiological level endogenous level endogenous endogenous endogenous level 7 unspecified role unspecified role prey prey subcellular prep subcellular preparation subcellular prep physiological level physiological level endogenous level endogenous endogenous endogenous level phosphorylated Ser opser O-phospho-L-serine (2S)-2-amino-3-(phosphonooxy)propanoic acid 2-amino-3-hydroxypropanoic acid 3-phosphate 2-azanyl-3-(phosphonooxy)propanoic acid ACT_SITE Phosphoserine intermediate MOD_RES Phosphoserine O-phospho-L-serine O-phosphonoserine O-phosphorylated L-serine O3-phosphoserine serine phosphate ester OPSer Phospho Phospho Seryl Phosphorylation phosphorylations sequence tag sequence tag identification certain certain sequence position certain certain certain sequence position certain observed-ptm observed-ptm observed ptm observed-ptm phosphorylated Ser opser O-phospho-L-serine (2S)-2-amino-3-(phosphonooxy)propanoic acid 2-amino-3-hydroxypropanoic acid 3-phosphate 2-azanyl-3-(phosphonooxy)propanoic acid ACT_SITE Phosphoserine intermediate MOD_RES Phosphoserine O-phospho-L-serine O-phosphonoserine O-phosphorylated L-serine O3-phosphoserine serine phosphate ester OPSer Phospho Phospho Seryl Phosphorylation phosphorylations sequence tag sequence tag identification certain certain sequence position certain certain certain sequence position certain observed-ptm observed-ptm observed ptm observed-ptm physical association physical association Table 1. Fig.1A