IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation. The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation. Molecular cell 2010 imex curation Tripathi V., Ellis JD., Shen Z., Song DY., Pan Q., Watt AT., Freier SM., Bennett CF., Sharma A., Bubulya PA., Blencowe BJ., Prasanth SG., Prasanth KV. kumarp@life.illinois.edu 09-May-2019: Contacted by IntAct-Help. Only protein-protein interactions imex curation human-hela Homo sapiens epitheloid cervix carcinoma cells Human hela Human epitheloid cervix carcinoma HeLa cells derivation: cervix; epithelial; adenocarcinoma ATCC no:CCL-2 rna-ip rna immunoprecipitation rna-ip rt-pcr reverse transcription pcr RT-PCR Tripathi V., Ellis JD., Shen Z., Song DY., Pan Q., Watt AT., Freier SM., Bennett CF., Sharma A., Bubulya PA., Blencowe BJ., Prasanth SG., Prasanth KV. kumarp@life.illinois.edu Accepted 2018-JUL-20 AT 14:11 BST AT 14:11 BST by LIVIAP Molecular cell 2010 imex curation spero di aver capito bene per la binding region! Ho spostato gli esp di clipseq nel pmid originale The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation. The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation. Molecular cell 2010 imex curation Tripathi V., Ellis JD., Shen Z., Song DY., Pan Q., Watt AT., Freier SM., Bennett CF., Sharma A., Bubulya PA., Blencowe BJ., Prasanth SG., Prasanth KV. kumarp@life.illinois.edu 09-May-2019: Contacted by IntAct-Help. Only protein-protein interactions imex curation human-hela Homo sapiens epitheloid cervix carcinoma cells Human hela Human epitheloid cervix carcinoma HeLa cells derivation: cervix; epithelial; adenocarcinoma ATCC no:CCL-2 fluorescence imaging fluorescence microscopy fluorescence imaging tag fluorescence tag visualisation by fluorescence tag fluorescence Tripathi V., Ellis JD., Shen Z., Song DY., Pan Q., Watt AT., Freier SM., Bennett CF., Sharma A., Bubulya PA., Blencowe BJ., Prasanth SG., Prasanth KV. kumarp@life.illinois.edu Accepted 2018-JUL-20 AT 14:11 BST AT 14:11 BST by LIVIAP Molecular cell 2010 imex curation spero di aver capito bene per la binding region! Ho spostato gli esp di clipseq nel pmid originale The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation. The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation. Molecular cell 2010 imex curation Tripathi V., Ellis JD., Shen Z., Song DY., Pan Q., Watt AT., Freier SM., Bennett CF., Sharma A., Bubulya PA., Blencowe BJ., Prasanth SG., Prasanth KV. kumarp@life.illinois.edu 09-May-2019: Contacted by IntAct-Help. Only protein-protein interactions imex curation human-hela Homo sapiens epitheloid cervix carcinoma cells Human hela Human epitheloid cervix carcinoma HeLa cells derivation: cervix; epithelial; adenocarcinoma ATCC no:CCL-2 fluorescence imaging fluorescence microscopy fluorescence imaging immunocytochemistry immunocytochemistry Tripathi V., Ellis JD., Shen Z., Song DY., Pan Q., Watt AT., Freier SM., Bennett CF., Sharma A., Bubulya PA., Blencowe BJ., Prasanth SG., Prasanth KV. kumarp@life.illinois.edu Accepted 2018-JUL-20 AT 14:11 BST AT 14:11 BST by LIVIAP Molecular cell 2010 imex curation spero di aver capito bene per la binding region! Ho spostato gli esp di clipseq nel pmid originale The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation. The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation. Molecular cell 2010 imex curation Tripathi V., Ellis JD., Shen Z., Song DY., Pan Q., Watt AT., Freier SM., Bennett CF., Sharma A., Bubulya PA., Blencowe BJ., Prasanth SG., Prasanth KV. kumarp@life.illinois.edu 09-May-2019: Contacted by IntAct-Help. Only protein-protein interactions imex curation human-hela Homo sapiens epitheloid cervix carcinoma cells Human hela Human epitheloid cervix carcinoma HeLa cells derivation: cervix; epithelial; adenocarcinoma ATCC no:CCL-2 rna-ip rna immunoprecipitation rna-ip q-pcr quantitative pcr q-pcr Tripathi V., Ellis JD., Shen Z., Song DY., Pan Q., Watt AT., Freier SM., Bennett CF., Sharma A., Bubulya PA., Blencowe BJ., Prasanth SG., Prasanth KV. kumarp@life.illinois.edu Accepted 2018-JUL-20 AT 14:11 BST AT 14:11 BST by LIVIAP Molecular cell 2010 imex curation spero di aver capito bene per la binding region! Ho spostato gli esp di clipseq nel pmid originale lncrn_neat1 human short Homo sapiens nuclear paraspeckle assembly transcript 1 (NEAT1) short isoform lncrna long non-coding ribonucleic acid lncRNA long non coding RNA long non coding ribonucleic acid long non-coding RNA lncrna human Homo sapiens Human GGAGUUAGCGACAGGGAGGGAUGCGCGCCUGGGUGUAGUUGUGGGGGAGGAAGUGGCUAGCUCAGGGCUUCAGGGGACAGACAGGGAGAGAUGACUGAGUUAGAUGAGACGAGGGGGCGGGCUGGGGGUGCGAGAAGGAAGCUUGGCAAGGAGACUAGGUCUAGGGGGACCACAGUGGGGCAGGCUGCAUGGAAAAUAUCCGCAGGGUCCCCCAGGCAGAACAGCCACGCUCCAGGCCAGGCUGUCCCUACUGCCUGGUGGAGGGGGAACUUGACCUCUGGGAGGGCGCCGCUCUUGCAUAGCUGAGCGAGCCCGGGUGCGCUGGUCUGUGUGGAAGGAGGAAGGCAGGGAGAGGUAGAAGGGGUGGAGGAGUCAGGAGGAAUAGGCCGCAGCAGCCCUGGAAAUGAUCAGGAAGGCAGGCAGUGGGUGCAGGGCUGCAGGAGGGCCGGGAGGGCUAAUCUUCAACUUGUCCAUGCCAGCAGCCCCUUUUUUUCCAGACCAAGGGCUGUGAACCCGCCUGGGGAUGAGGCCUGGUCUUGUGGAACUGAACUUAGCUCGACGGGGCUGACCGCUCUGGCCCAGGGUGGUAUGUAAUUUUCGCUCGGCCUGGGACGGGGCCCAGGCCGGGCCCAGCCUGGUGGAGCGUCCAGGUCUGGGUGCGAAGCCAGGCCCCUGGGCGGAGGUGAGGGGUGGUCUGAGGAGUGAUGUGGAGUUAAGGCGCCAUCCUCACCGGUGACUGGUGCGGCACCUAGCAUGUUUGACAGGCGGGGACUGCGAGGCACGCUGCUCGGGUGUUGGGGACAACAUUGACCAACGCUUUAUUUUCCAGGUGGCAGUGCUCCUUUUGGACUUUUCUCUAGGUUUGGCGCUAAACUCUUCUUGUGAGCUCACUCCACCCCUUCUUCCUCCCUUUAACUUAUCCAUUCACUUAAAACAUUACCUGGUCAUCUGGUAAGCCCGGGACAGUAAGCCGAGUGGCUGUUGGAGUCGGUAUUGUUGGUAAUGGUGGAGGAAGAGAGGCCUUCCCGCUGAGGCUGGGGUGGGGCGGAUCGGUGUUGCUUGCCUGCAGAGAGGGUGGGGAGUGAAUGUGCACCCUUGGGUGGGCCUGCAGCCAUCCAGCUGAAAGUUACAAAAAUGCUUCAUGGACCGUGGUUUGUUACUAUAGUGUUCCUCAUGGCGAGCAGAUGGAACCGGGAGACAUGGAGUCCCUGGCCAGUGUGAGUCCUAGCAUUGCAGGAGGGGAGACCCUGGAGGAGAGAGCCCGCCUCAAUUGAUGCCUGCAGAUUGAAUUUCCAGAGGCUUAGGAGGAGGAAGUUCUCCAAUGUUCUGUUUCCAGGCCUUGCUCAGGAAGCCCUGUAUUCAGGAGGCUACCAUUUAAAGUUUGCAGAUGAGCUUAUGGGGGGCAAUCUUAAAAAGUCCACAGCAGAUGCAUCCGGCUCGAGGGGCCAUCAGCUUUGAAUAAAUGCUUGUUCCAGAGCCCAUGAAUGCCAGCAGGCACCCCUCCUUUCCUGGGGUAAAGGUUUUCAGAUGCUGCAUCUUCUAAAUUGAGCCUCCGGUCAUACUAGUUUUGUGCUUGGAACCUUGCUUCAAGAAGAUCCCUAAGCUGUAGAACAUUUUAACGUUGAUGCCACAACGCAGAUUGAUGCCUUGUAGAUGGAGCUUGCAGAUGGAGCCCCGUGACCUCUCACCUACCCACCUGUUUGCCUGCCUUCUUGUGCGUUUCUCGGAGAAGUUCUUAGCCUGAUGAAAUAACUUGGGGCGUUGAAGAGCUGUUUAAUUUUAAAUGCCUUAGACUGGGGAUAUAUUAGAGGAAGCAGAUUGUCAAAUUAAGGGUGUCAUUGUGUUGUGCUAAACGCUGGGAGGGUACAAGUUGGUCAUUCCUAAAUCUGUGUGUGAGAAAUGGCAGGUCUAGUUUGGGCAUUGUGAUUGCAUUGCAGAUUACUAGGAGAAGGGAAUGGUGGGUACACCGGUAGUGCUCUUUUGUUCUUGCUUCGUUUUUUUAAACUUGAACUUUACUUCGUUAGAUUUCAUAAUACUUUCUUGGCAUUCUAGUAAGAGGACCCUGAGGUGGGAGUUGUGGGGGACGGGGAGAAGGGGACAGCUUGGCACCGGUCCCGUGGGCGUUGCAGUGUGGGGGAUGGGGGUAUGCAGCUUGGCACUGGUACUGGGAGGGAUGAGGGUGAAGAAGGGGAGAGGGUUGGUUAGAGAUACAGUGUGGGUGGUGGGGGUGGUAGGAAAUGCAGGUUGAAGGGAAUUCUCUGGGGCUUUGGGGAAUUUAGUGCGUGGGUGAGCCAAGAAAAUACUAAUUAAUAAUAGUAAGUUGUUAGUGUUGGUUAAGUUGUUGCUUGGAAGUGAGAAGUUGCUUAGAAACUUUCCAAAGUGCUUAGAACUUUAAGUGCAAACAGACAAACUAACAAACAAAAAUUGUUUUGCUUUGCUACAAGGUGGGGAAGACUGAAGAAGUGUUAACUGAAAACAGGUGACACAGAGUCACCAGUUUUCCGAGAACCAAAGGGAGGGGUGUGUGAUGCCAUCUCACAGGCAGGGGAAAUGUCUUUACCAGCUUCCUCCUGGUGGCCAAGACAGCCUGUUUCAGAGGGUUGUUUUGUUUGGGGUGUGGGUGUUAUCAAGUGAAUUAGUCACUUGAAAGAUGGGCGUCAGACUUGCAUACGCAGCAGAUCAGCAUCCUUCGCUGCCCCUUAGCAACUUAGGUGGUUGAUUUGAAACUGUGAAGGUGUGAUUUUUUCAGGAGCUGGAAGUCUUAGAAAAGCCUUGUAAAUGCCUAUAUUGUGGGCUUUUAACGUAUUUAAGGGACCACUUAAGACGAGAUUAGAUGGGCUCUUCUGGAUUUGUUCCUCAUUUGUCACAGGUGUCUUGUGAUUGAAAAUCAUGAGCGAAGUGAAAUUGCAUUGAAUUUCAAGGGAAUUUAGUAUGUAAAUCGUGCCUUAGAAACACAUCUGUUGUCUUUUCUGUGUUUGGUCGAUAUUAAUAAUGGCAAAAUUUUUGCCUAUCUAGUAUCUUCAAAUUGUAGUCUUUGUAACAACCAAAUAACCUUUUGUGGUCACUGUAAAAUUAAUAUUUGGUAGACAGAAUCCAUGUACCUUUGCUAAGGUUAGAAUGAAUAAUUUAUUGUAUUUUUAAUUUGAAUGUUUGUGCUUUUUAAAUGAGCCAAGACUAGAGGGGAAACUAUCACCUAAAAUCAGUUUGGAAAACAAGACCUAAAAAGGGAAGGGGAUGGGGAUUGUGGGGAGAGAGUGGGCGAGGUGCCUUUACUACAUGUGUGAUCUGAAAACCCUGCUUGGUUCUGAGCUGCGUCUAUUGAAUUGGUAAAGUAAUACCAAUGGCUUUUUAUCAUUUCCUUCUUCCCUUUAAGUUUCACUUGAAAUUUUAAAAAUCAUGGUUAUUUUUAUCGUUGGGAUCUUUCUGUCUUCUGGGUUCCAUUUUUUAAAUGUUUAAAAAUAUGUUGACAUGGUAGUUCAGUUCUUAACCAAUGACUUGGGGAUGAUGCAAACAAUUACUGUCGUUGGGAUUUAGAGUGUAUUAGUCACGCAUGUAUGGGGAAGUAGUCUCGGGUAUGCUGUUGUGAAAUUGAAACUGUAAAAGUAGAUGGUUGAAAGUACUGGUAUGUUGCUCUGUAUGGUAAGAACUAAUUCUGUUACGUCAUGUACAUAAUUACUAAUCACUUUUCUUCCCCUUUACAGCACAAAUAAAGUUUGAGUUCUAAACUCAUUAGAAAAAAAAAAAAAAAAAAAAAAA prp6_human Pre-mRNA-processing factor 6 U5 snRNP-associated 102 kDa protein PRP6 homolog PRPF6 C20orf14 Androgen receptor N-terminal domain-transactivating protein 1 protein protein human Homo sapiens Human MNKKKKPFLGMPAPLGYVPGLGRGATGFTTRSDIGPARDANDPVDDRHAPPGKRTVGDQMKKNQAADDDDEDLNDTNYDEFNGYAGSLFSSGPYEKDDEEADAIYAALDKRMDERRKERREQREKEEIEKYRMERPKIQQQFSDLKRKLAEVTEEEWLSIPEVGDARNKRQRNPRYEKLTPVPDSFFAKHLQTGENHTSVDPRQTQFGGLNTPYPGGLNTPYPGGMTPGLMTPGTGELDMRKIGQARNTLMDMRLSQVSDSVSGQTVVDPKGYLTDLNSMIPTHGGDINDIKKARLLLKSVRETNPHHPPAWIASARLEEVTGKLQVARNLIMKGTEMCPKSEDVWLEAARLQPGDTAKAVVAQAVRHLPQSVRIYIRAAELETDIRAKKRVLRKALEHVPNSVRLWKAAVELEEPEDARIMLSRAVECCPTSVELWLALARLETYENARKVLNKARENIPTDRHIWITAAKLEEANGNTQMVEKIIDRAITSLRANGVEINREQWIQDAEECDRAGSVATCQAVMRAVIGIGIEEEDRKHTWMEDADSCVAHNALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPKAEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENDEYERARRLLAKARSSAPTARVFMKSVKLEWVQDNIRAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQECPNSGILWSEAIFLEARPQRRTKSVDALKKCEHDPHVLLAVAKLFWSQRKITKAREWFHRTVKIDSDLGDAWAFFYKFELQHGTEEQQEEVRKRCESAEPRHGELWCAVSKDIANWQKKIGDILRLVAGRIKNTF 91C2F1ADCA439BE9 pspc1_human Paraspeckle component 1 PSPC1 PSP1 Paraspeckle protein 1 protein protein human Homo sapiens Human MMLRGNLKQVRIEKNPARLRALESAVGESEPAAAAAMALALAGEPAPPAPAPPEDHPDEEMGFTIDIKSFLKPGEKTYTQRCRLFVGNLPTDITEEDFKRLFERYGEPSEVFINRDRGFGFIRLESRTLAEIAKAELDGTILKSRPLRIRFATHGAALTVKNLSPVVSNELLEQAFSQFGPVEKAVVVVDDRGRATGKGFVEFAAKPPARKALERCGDGAFLLTTTPRPVIVEPMEQFDDEDGLPEKLMQKTQQYHKEREQPPRFAQPGTFEFEYASRWKALDEMEKQQREQVDRNIREAKEKLEAEMEAARHEHQLMLMRQDLMRRQEELRRLEELRNQELQKRKQIQLRHEEEHRRREEEMIRHREQEELRRQQEGFKPNYMENREQEMRMGDMGPRGAINMGDAFSPAPAGNQGPPPMMGMNMNNRATIPGPPMGPGPAMGPEGAANMGTPMMPDNGAVHNDRFPQGPPSQMGSPMGSRTGSETPQAPMSGVGPVSGGPGGFGRGSQGGNFEGPNKRRRY 3A8C44079D64BBF0 srsf1_mouse Serine/arginine-rich splicing factor 1 Sfrs1 Splicing factor, arginine/serine-rich 1 Srsf1 ASF/SF2 Pre-mRNA-splicing factor SRp30a protein protein mouse Mus musculus Mouse MSGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAEDAVYGRDGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRGRYGPPSRRSENRVVVSGLPPSGSWQDLKDHMREAGDVCYADVYRDGTGVVEFVRKEDMTYAVRKLDNTKFRSHEGETAYIRVKVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPRHSRSRSRT DIP protein Q6PDM2 original sequence version: 80 C28A0B2F112EA713 srsf2_human Serine/arginine-rich splicing factor 2 Splicing factor SC35 Splicing component, 35 kDa Protein PR264 SRSF2 SFRS2 Splicing factor, arginine/serine-rich 2 protein protein human Homo sapiens Human MSYGRPPPDVEGMTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMDAMDGAVLDGRELRVQMARYGRPPDSHHSRRGPPPRRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSPPKSPEEEGAVSS DIP protein Q01130 original sequence version: 169 68121AC4D35714FA srsf1_human Serine/arginine-rich splicing factor 1 SF2 SF2P33 OK/SW-cl.3 SRSF1 ASF pre-mRNA-splicing factor SF2, P33 subunit Alternative-splicing factor 1 SFRS1 Splicing factor, arginine/serine-rich 1 protein protein human Homo sapiens Human MSGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAEDAVYGRDGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRGRYGPPSRRSENRVVVSGLPPSGSWQDLKDHMREAGDVCYADVYRDGTGVVEFVRKEDMTYAVRKLDNTKFRSHEGETAYIRVKVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPRHSRSRSRT DIP protein Q07955 original sequence version: 191 DIP protein Q07955 original sequence version: 160 C28A0B2F112EA713 srsf5_human Serine/arginine-rich splicing factor 5 Pre-mRNA-splicing factor SRP40 Delayed-early protein HRS SRSF5 HRS SRP40 SFRS5 Splicing factor, arginine/serine-rich 5 protein protein human Homo sapiens Human MSGCRVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRSVDSGN DIP protein Q13243 original sequence version: 146 F13AD79845ECBB16 srsf3_human Serine/arginine-rich splicing factor 3 Pre-mRNA-splicing factor SRP20 SRSF3 SRP20 SFRS3 Splicing factor, arginine/serine-rich 3 protein protein human Homo sapiens Human MHRDSCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDAADAVRELDGRTLCGCRVRVELSNGEKRSRNRGPPPSWGRRPRDDYRRRSPPPRRRSPRRRSFSRSRSRSLSRDRRRERSLSRERNHKPSRSFSRSRSRSRSNERK DIP protein P84103 original sequence version: 125 02F0A5EE33FF28A0 snrna u2-1 Small nuclear RNA U2-1 snrna small nuclear rna snRNA snrna human Homo sapiens Human AUCGCUUCUCGGCCUUUUGGCUAAGAUCAAGUGUAGUAUCUGUUCUUAUCAGUUUAAUAUCUGAUACGUCCUCUAUCCGAGGACAAUAUAUUAAAUGGAUUUUUGGAGCAGGGAGAUGGAAUAGGAGCUUGCUCCGUCCACUCCACGCAUCGACCUGGUAUUGCAGUACCUCCAGGAACGGUGCACCC lncrn_malat1 mouse lncrna long non-coding ribonucleic acid lncRNA long non coding RNA long non coding ribonucleic acid long non-coding RNA lncrna mouse Mus musculus Mouse AGGCATTCAGGCAGCGAGAGCAGAGCAGCGTAGAGCAGCACAGCTGAGCTCGTGAGGCAGGAGACTCAGCCCGAGGAAATCGCAGATAAGTTTTTAATTAAAAAGATTGAGCAGTAAAAAGAATTAGAACTCTAAACTTAAGCTAATAGAGTAGCTTATCGAAATATTACTTAGTCTTAATAATCTAAGAAGATCTTAAGAGATAACATGAAGGCTTATTTAAACAGTTTGAAAAAGGAAATGAGGAGAAAAGTATTTGTACTGTATAATGGAGGCTGACCAGAGCAGTTTAGGAGATTGTAAAGGGAGGTTTTGTGAAGTTCTAAAAGGTTCTAGTTTGAAGGTCGGCCTTGTAGATTAAAACGAAGGTTACCTAAATAGAATCTAAGTGGCATTTAAAACAGTAAAGTTGTAGAGAATAGTTTGAAAATGAGGTGTAGTTTTAAAAGATTGAGAAAAGTAGGTTAAGTTGACGGCCGTTATAAAAATCCTTCGACTGGCGCATGTACGTTTGAAGGCATGAGTTGGAAACAGGGAAGATGGAAGTGTTAGGCTAGCCGGGCGATGGTGGCGCACGCCTTTAATCCTAGCACTTGGGAGGCAGAGGCAGGCGGATTTCTGAGTTCGAGGCCAGCCTGGTCTACAGAGTGAGTTCCAGGACAGCCAGGGCTACACAGAGAAACCCTGTCTTGAAAAAACAAAAAGGTTAGGCTAGTATTTGGAGAAAGAAGATTAGAAAATGGAAGTGAAAGACGAAGAAGACATACAGGAAGGTGAAGAAAAAGCTGTTAGAGAAGATAGGAAAATAGAAGACAAAGCATCTTTAGAAGACAGAAAAGGTACTTAAAGGCACAGGTAGTAGGAAGCCGAAGAATAGAAGATAGAAAGAAGCAAGATAGAAAAACAAAATGGAAGTTAAGACAACTTTGGATGCCAGCATTCAAGATAGGCAAAGAAGATAAGATTGAGGCCAAAAGGTTGGATAAGATATAAAGTCAGAAGGAAATTATCTTTAAAGCCATAAGTTCAAATTTCTGATGGAGCGAGCAGTTTAGAAGAGTCTTTAGACAGCCACATACAAGATTGAAGCTAGCAATCAAAGCTACTAGGACTGAAGTAAAAAGTTAAGGCAGAATGCCTTTGAAGAGTTAGAAGAATATTAAAAGCCTTAACTTGTAGCTTAATTTTGCTTGATGACAAAAGGACTTTTGATAACAGTTTCAAGATTGTCAGCATTTTGCATTGGACTTGAGCTGAGGTGCTTTTAAAATCCTAACGACTAGCATTGGCAGCTGACCCAGGTCTACACAGAAGTGCATTCAGTGAACTAGGAAGACAGGAGCGGCAGACAGGAGTCCCGAAGCCAGTTTGGTGAAGCTAGGAAGGACTGAGGAGCCAGCAGCAGCAGTGCATGGTGAAGATAGCCCAGGAAAGAGTGCGGTTCGGTGGAGGAAGCTAGGAAGAAGGAGCCATACGGATGTGGTGGTGAAGCTGGGAAAGGGTTCCAGGATGGTGGAGCGAGAGCGAGTTGGTGATGAAGCTAGCTGGCGGCTTGGCTTGTCAACTGCGCGGAGGAGGCGAGCAGGCATTGTGGAGAGGATAGATAGCGGCTCCTAGACCAGCATGCCAGTGTGCAAGAAAGGCTGCAGGGAGAGCATGCGGTGCGGTAACATTCCTTGAGGTCGGCAACATGGTGGTGGTTTTCTGTAACTTGGATGGTAACTTGTTTACTTTGTCTTAATAGTTATGGGGGAGTTGTAGGCTTCTGTGTAAAGAGATATATCTGGGGCTGTATGTAGGCCTTTGCGGGTGTTGTAGGTTTTTCTTTTTCAGGGTTATGTCCTCTTGCATCTTGTCAGAAGCTTTTGAGGGCTGACTGCCAAGGCCCAGAAAGAAGAATGGTAGATGGCAAGTTGTCTTTAACCGCTCAGAGGGGAATGAATGGTAGAGCCAGCACAACCTCCCAGTTTTGTAAGACGTTGTAGTTTGAACAGATGACCTACCACAAGCCTCACTCCTGTGTAGGGGAGGTAATTGGGCAAAGTGCTTTTGGGGGAATGGGGGCAAAATATATTTTGAGTTCTTTTCCCCTTAGGTCTGTCTAGAATCCTAAAGGCAGATGACTCAAGGGAACCAGAAAAAAGGAAATCCACTCTCAGGATAAGCAGAGCTCGCCAGGTTTACAGTTTGTAGGAAGTAGAGGATGGATGCTAGCTTTCACACTGAGTGTGGAGGAGCTGGCCATGGCGGAATTGCTGGTAGTTTACTCTTTCCCCCTCCCTTAATGAGATTTGTAAAATCCTAAACACTTTTACTTGAAATATTTGGGAGTGGTCTTAACAGGGAGGAGTGGGTGGGGGAAACGTTTTTTTTCTAAGATTTTCCACAGATGCTATAGTTGTGTTGACACACTGGGTTAGAGAAGGCGTGTACTGCTATGCTGTTGGCACGACACCTTCAGGGACTGGAGCTGCCTTTTGTCCTTGGAAGAGTTTTCCCAGTTGCCGCTGAAGTCAGCACAGTGCGGCTTTGGTTCACAGTCACCTCAGGAGAACCTCAGGAGCTTGGCTAGGCCAGAGGTTGAAGTTAAGTTTTACAGCACCGTGATTTAAAATATTTCATTAAAGGGGAGGGGTAAAACTTAGTTGGCTGTGGCCTTGTGTTTGGGTGGGTGGGGGTGTTAGGTAATTGTTTAGTTTATGATTTCAGATAATCATACCAGAGAACTTAAATATTTGGAAAAACAGGAAATCTCAGCTTTCAAGTTGGCAAGTAACTCCCAATCCAGTTTTTGCTTCTTTTTTCCTTTTTCTTTTTTTGAGGCGGGCAGCTAAGGAAGGTTGGTTCCTCTGCCGGTCCCTCGAAAGCGTAGGGCTTGGGGGTTGGTCTGGTCCACTGGGATGATGTGATGCTACAGTGGGGACTCTTCTGAAGCTGTTGGATGAATATAGATTGTAGTGTGTGGTTCTCTTTTGAAATTTTTTTCAGGTGACTTAATGTATCTTAATAACTACTATAGGAACAAAGGAAGTGGCTTTAATGACCCTGAAGGAATTTCTTCTGGTGATAGCTTTTATATTATCAAGTAAGAGATACTATCTCAGTTTTGTATAAGCAAGTCTTTTTCCTAGTGTAGGAGAAATGATTTTCCTTGTGACTAAACAAGATGTAAAGGTATGCTTTTTTTCTTCTTGTGCATTGTATACTTGTGTTTATTTGTAACTTATAATTTAAGAATTATGATAATTCAGCCTGAATGTCTTTTAGAGGGTGGGCTTTTGTTGATGAGGGAGGGGAAACCTTTTTTTTTCTGTAGACCTTTTTCAGATAACACCATCTGAGTCATAACCAGCCTGGCAGTGTGATGACGTAGATGCAGAGGGAGCAGCTCCTTGGTGAATGAGTGATAAGTAAAGGCAGAAAAAATAATGTCATGTCTCCATGGGGAATGAGCATGAGCCAGAGATTGTTCCTACTGATGAAAAGCTGCATATGCAAAAATTTAAGCAAATGAAAGCAACCAGTATAAAGTTATGGCAATACCTTTAAAAGTTATGGCTTATCTACCAAGCTTTATCCACAAAAGTAAAGAATTGATGAAAAACAGTGAAGATCAAATGTTCATCTCAAAACTGCTTTTACAAAAGCAGAATAGAAATGAAGTGAAAATGCTGCATTAAGCCTGGAGTAAAAAGAAGCTGAGCTTGTTGAGATGAGTGGGATCGAGCGGCTGCGAGGCGGTGCAGTGTGCCAATGTTTCGTTTGCCTCAGACAGGTTTCTCTTCATAAGCAGAAGAGTTGCTTCATTCCATCTCGGAGCAGGAAACAGCAGACTGCTGTTGACAGATAAGTGTAACTTGGATCTGCAGTATTGCATGTTAGGGATAGATAAGTGCCTTTTTTCTCTTTTTCCAAAAAGACCTGTAGAGCTGTTGAATGTTTGCAGCTGGCCCCTCTTAGGCAGTTCAGAATTTTGAGTAGTTTTCCCATCCAGCCTCTTAAAAATTCCTAAGCCTTGCACCGATGGGCTTTCATGATGGGATAGCTAATAGGCTTTTGCATCGTAAACTTCAACACAAAAGCCTACATGATTAATGCCTACTTTAATTACATTGCTTACAAGATTAAGGAATCTTTATCTTGAAGACCCCATGAAAGGGATCATTATGTGCTGAAAATTAGATGTTCATATTGCTAAAATTTAAATGTGCTCCAATGTACTTGTGCTTAAAATCATTAAATTATACAAATTAATAAAATACTTCACTAGAGAATGTATGTATTTAGAAGGCTGTCTCCTTATTTAAATAAAGTCTTGTTTGTTGTCTGTAGTTAGTGTGGGCAATTTTGGGGGGATGTTCTTCTCTAATCTTTTCAGAAACTTGACTTCGAACACTTAAGTGGACCAGATCAGGATTTGAGCCAGAAGACCGAAATTAACTTTAAGGCAGGAAAGACAAATTTTATTCTCCATGCAGTGATGAGCATTTAATAATTGCAGGCCTGGCATAGAGGCCGTCTAACTAAGGACTAAGTACCTTAGGCAGGTGGGAGATGATGGTCAGAGTAAAAGGTAACTACATATTTTGTTTCCAGAAAGTCAGGGGTCTAATTTGACCATGGCTAAACATCTAGGGTAAGACACTTTTCCCCCACATTTCCAAATATGCATGTTGAGTTTAAATGCTTACGATCATCTCATCCACTTTAGCCTTTTGTCACCTCACTTGAGCCACGAGTGGGGTCAGGCATGTGGGTTTAAAGAGTTTTCCTTTGCAGAGCCTCATTTCATCCTTCATGGAGCTGCTCAGGACTTTGCATATAAGCGCTTGCCTCTGTCTTCTGTTCTGCTAGTGAGTGTGTGATGTGAGACCTTGCAGTGAGTTTGTTTTTCCTGGAATGTGGAGGGAGGGGGGGATGGGGCTTACTTGTTCTAGCTTTTTTTTTACAGACCACACAGAATGCAGGTGTCTTGACTTCAGGTCATGTCTGTTCTTTGGCAAGTAATATGTGCAGTACTGTTCCAATCTGCTGCTATTAGAATGCATTGTGACGCGACTGGAGTATGATTAAAGAAAGTTGTGTTTCCCCAAGTGTTTGGAGTAGTGGTTGTTGGAGGAAAAGCCATGAGTAACAGGCTGAGTGTTGAGGAAATGGCTCTCTGCAGCTTTAAGTAACCCGTGTTTGTGATTGGAGCCGAGTCCCTTTGCTGTGCTGCCTTAGGTAAATGTTTTTGTTCATTTCTGGTGAGGGGGGTTGGGAGCACTGAAGCCTTTAGTCTCTTCCAGATTCAACTTAAAATCTGACAAGAAATAAATCAGACAAGCAACATTCTTGAAGAAATTTTAACTGGCAAGTGGAAATGTTTTGAACAGTTCCGTGGTCTTTAGTGCATTATCTTTGTGTAGGTGTTCTCTCTCCCCTCCCTTGGTCTTAATTCTTACATGCAGGAACATTGACAACAGCAGACATCTATCTATTCAAGGGGCCAGAGAATCCAGACCCAGTAAGGAAAAATAGCCCATTTACTTTAAATCGATAAGTGAAGCAGACATGCCATTTTCAGTGTGGGGATTGGGAAGCCCTAGTTCTTTCAGATGTACTTCAGACTGTAGAAGGAGCTTCCAGTTGAATTGAAATTCACCAGTGGACAAAATGAGGACAACAGGTGAACGAGCCTTTTCTTGTTTAAGATTAGCTACTGGTAATCTAGTGTTGAATCCTCTCCAGCTTCATGCTGGAGCAGCTAGCATGTGATGTAATGTTGGCCTTGGGGTGGAGGGGTGAGGTGGGCGCTAAGCCTTTTTTTAAGATTTTTCAGGTACCCCTCACTAAAGGCACTGAAGGCTTAATGTAGGACAGCGGAGCCTTCCTGTGTGGCAAGAATCAAGCAAGCAGTATTGTATCGAGACCAAAGTGGTATCATGGTCGGTTTTGATTAGCAGTGGGGACTACCCTACCGTAACACCTTGTTGGAATTGAAGCATCCAAAGAAAATACTTGAGAGGCCCTGGGCTTGTTTTAACATCTGGAAAAAAGGCTGTTTTTATAGCAGCGGTTACCAGCCCAAACCTCAAGTTGTGCTTGCAGGGGAGGGAAAAGGGGGAAAGCGGGCAACCAGTTTCCCCAGCTTTTCCAGAATCCTGTTACAAGGTCTCCCCACAAGTGATTTCTCTGCCACATCGCCACCATGGGCCTTTGGCCTAATCACAGACCCTTCACCCCTCACCTTGATGCAGCCAGTAGCTGGATCCTTGAGGTCACGTTGCATATCGGTTTCAAGGTAACCATGGTGCCAAGGTCCTGTGGGTTGCACCAGAAAAGGCCATCAATTTTCCCCTTGCCTGTAATTTAACATTAAAACCATAGCTAAGATGTTTTATACATAGCACCTATGCAGAGTAAACAAACCAGTATGGGTATAGTATGTTTGATACCAGTGCTGGGTGGGAATGTAGGAAGTCGGATGAAAAGCAAGCCTTTGTAGGAAGTTGTTGGGGTGGGATTGCAAAAATTCTCTGCTAAGACTTTTTCAGGTGGACATAACAGACTTGGCCAAGCTAGCATCTTAGTGGAAGCAGATTCGTCAGTAGGGTTGTAAAGGTTTTTCTTTTCCTGAGAAAACAACCTTTTGTTTTCTCAGGTTTTGCTTTTTGGCCTTTCCCTAGCTTTAAAAAAAAAAAAGCAAAAGACGCTGGTGGCTGGCACTCCTGGTTTCCAGGACGGGGTTCAAGTCCCTGCGGTGTCTTTGCTTGACTCTTATATCATGAGGCCATTACATTTTTCTTGGAGGGTTCTAAAGGCTCTGGGTATGGTAGCTGATATCACTGGAACACTCCCCAGCCTCAGTGTTGAACTCTTGATAATTAACTGCATTGTCTTTCAGGTTATGCCCAATTCGTCTTATTACCTCTGAGTCGACACACCTCCTACTATTTATTGAATACTTTGATTTTATGAAATAAAAACTAAATATCTCTCA lncrn_malat1 human metastasis associated lung adenocarcinoma transcript 1 lncrna long non-coding ribonucleic acid lncRNA long non coding RNA long non coding ribonucleic acid long non-coding RNA lncrna human Homo sapiens Human CGCAGCCUGCAGCCCGAGACUUCUGUAAAGGACUGGGGCCCCGCAACUGGCCUCUCCUGCCCUCUUAAGCGCAGCGCCAUUUUAGCAACGCAGAAGCCCGGCGCCGGGAAGCCUCAGCUCGCCUGAAGGCAGGUCCCCUCUGACGCCUCCGGGAGCCCAGGUUUCCCAGAGUCCUUGGGACGCAGCGACGAGUUGUGCUGCUAUCUUAGCUGUCCUUAUAGGCUGGCCAUUCCAGGUGGUGGUAUUUAGAUAAAACCACUCAAACUCUGCAGUUUGGUCUUGGGGUUUGGAGGAAAGCUUUUAUUUUUCUUCCUGCUCCGGUUCAGAAGGUCUGAAGCUCAUACCUAACCAGGCAUAACACAGAAUCUGCAAAACAAAAACCCCUAAAAAAGCAGACCCAGAGCAGUGUAAACACUUCUGGGUGUGUCCCUGACUGGCUGCCCAAGGUCUCUGUGUCUUCGGAGACAAAGCCAUUCGCUUAGUUGGUCUACUUUAAAAGGCCACUUGAACUCGCUUUCCAUGGCGAUUUGCCUUGUGAGCACUUUCAGGAGAGCCUGGAAGCUGAAAAACGGUAGAAAAAUUUCCGUGCGGGCCGUGGGGGGCUGGCGGCAACUGGGGGGCCGCAGAUCAGAGUGGGCCACUGGCAGCCAACGGCCCCCGGGGCUCAGGCGGGGAGCAGCUCUGUGGUGUGGGAUUGAGGCGUUUUCCAAGAGUGGGUUUUCACGUUUCUAAGAUUUCCCAAGCAGACAGCCCGUGCUGCUCCGAUUUCUCGAACAAAAAAGCAAAACGUGUGGCUGUCUUGGGAGCAAGUCGCAGGACUGCAAGCAGUUGGGGGAGAAAGUCCGCCAUUUUGCCACUUCUCAACCGUCCCUGCAAGGCUGGGGCUCAGUUGCGUAAUGGAAAGUAAAGCCCUGAACUAUCACACUUUAAUCUUCCUUCAAAAGGUGGUAAACUAUACCUACUGUCCCUCAAGAGAACACAAGAAGUGCUUUAAGAGGUAUUUUAAAAGUUCCGGGGGUUUUGUGAGGUGUUUGAUGACCCGUUUAAAAUAUGAUUUCCAUGUUUCUUUUGUCUAAAGUUUGCAGCUCAAAUCUUUCCACACGCUAGUAAUUUAAGUAUUUCUGCAUGUGUAGUUUGCAUUCAAGUUCCAUAAGCUGUUAAGAAAAAUCUAGAAAAGUAAAACUAGAACCUAUUUUUAACCGAAGAACUACUUUUUGCCUCCCUCACAAAGGCGGCGGAAGGUGAUCGAAUUCCGGUGAUGCGAGUUGUUCUCCGUCUAUAAAUACGCCUCGCCCGAGCUGUGCGGUAGGCAUUGAGGCAGCCAGCGCAGGGGCUUCUGCUGAGGGGGCAGGCGGAGCUUGAGGAAACCGCAGAUAAGUUUUUUUCUCUUUGAAAGAUAGAGAUUAAUACAACUACUUAAAAAAUAUAGUCAAUAGGUUACUAAGAUAUUGCUUAGCGUUAAGUUUUUAACGUAAUUUUAAUAGCUUAAGAUUUUAAGAGAAAAUAUGAAGACUUAGAAGAGUAGCAUGAGGAAGGAAAAGAUAAAAGGUUUCUAAAACAUGACGGAGGUUGAGAUGAAGCUUCUUCAUGGAGUAAAAAAUGUAUUUAAAAGAAAAUUGAGAGAAAGGACUACAGAGCCCCGAAUUAAUACCAAUAGAAGGGCAAUGCUUUUAGAUUAAAAUGAAGGUGACUUAAACAGCUUAAAGUUUAGUUUAAAAGUUGUAGGUGAUUAAAAUAAUUUGAAGGCGAUCUUUUAAAAAGAGAUUAAACCGAAGGUGAUUAAAAGACCUUGAAAUCCAUGACGCAGGGAGAAUUGCGUCAUUUAAAGCCUAGUUAACGCAUUUACUAAACGCAGACGAAAAUGGAAAGAUUAAUUGGGAGUGGUAGGAUGAAACAAUUUGGAGAAGAUAGAAGUUUGAAGUGGAAAACUGGAAGACAGAAGUACGGGAAGGCGAAGAAAAGAAUAGAGAAGAUAGGGAAAUUAGAAGAUAAAAACAUACUUUUAGAAGAAAAAAGAUAAAUUUAAACCUGAAAAGUAGGAAGCAGAAGAAAAAAGACAAGCUAGGAAACAAAAAGCUAAGGGCAAAAUGUACAAACUUAGAAGAAAAUUGGAAGAUAGAAACAAGAUAGAAAAUGAAAAUAUUGUCAAGAGUUUCAGAUAGAAAAUGAAAAACAAGCUAAGACAAGUAUUGGAGAAGUAUAGAAGAUAGAAAAAUAUAAAGCCAAAAAUUGGAUAAAAUAGCACUGAAAAAAUGAGGAAAUUAUUGGUAACCAAUUUAUUUUAAAAGCCCAUCAAUUUAAUUUCUGGUGGUGCAGAAGUUAGAAGGUAAAGCUUGAGAAGAUGAGGGUGUUUACGUAGACCAGAACCAAUUUAGAAGAAUACUUGAAGCUAGAAGGGGAAGUUGGUUAAAAAUCACAUCAAAAAGCUACUAAAAGGACUGGUGUAAUUUAAAAAAAACUAAGGCAGAAGGCUUUUGGAAGAGUUAGAAGAAUUUGGAAGGCCUUAAAUAUAGUAGCUUAGUUUGAAAAAUGUGAAGGACUUUCGUAACGGAAGUAAUUCAAGAUCAAGAGUAAUUACCAACUUAAUGUUUUUGCAUUGGACUUUGAGUUAAGAUUAUUUUUUAAAUCCUGAGGACUAGCAUUAAUUGACAGCUGACCCAGGUGCUACACAGAAGUGGAUUCAGUGAAUCUAGGAAGACAGCAGCAGACAGGAUUCCAGGAACCAGUGUUUGAUGAAGCUAGGACUGAGGAGCAAGCGAGCAAGCAGCAGUUCGUGGUGAAGAUAGGAAAAGAGUCCAGGAGCCAGUGCGAUUUGGUGAAGGAAGCUAGGAAGAAGGAAGGAGCGCUAACGAUUUGGUGGUGAAGCUAGGAAAAAGGAUUCCAGGAAGGAGCGAGUGCAAUUUGGUGAUGAAGGUAGCAGGCGGCUUGGCUUGGCAACCACACGGAGGAGGCGAGCAGGCGUUGUGCGUAGAGGAUCCUAGACCAGCAUGCCAGUGUGCCAAGGCCACAGGGAAAGCGAGUGGUUGGUAAAAAUCCGUGAGGUCGGCAAUAUGUUGUUUUUCUGGAACUUACUUAUGGUAACCUUUUAUUUAUUUUCUAAUAUAAUGGGGGAGUUUCGUACUGAGGUGUAAAGGGAUUUAUAUGGGGACGUAGGCCGAUUUCCGGGUGUUGUAGGUUUCUCUUUUUCAGGCUUAUACUCAUGAAUCUUGUCUGAAGCUUUUGAGGGCAGACUGCCAAGUCCUGGAGAAAUAGUAGAUGGCAAGUUUGUGGGUUUUUUUUUUUUACACGAAUUUGAGGAAAACCAAAUGAAUUUGAUAGCCAAAUUGAGACAAUUUCAGCAAAUCUGUAAGCAGUUUGUAUGUUUAGUUGGGGUAAUGAAGUAUUUCAGUUUUGUGAAUAGAUGACCUGUUUUUACUUCCUCACCCUGAAUUCGUUUUGUAAAUGUAGAGUUUGGAUGUGUAACUGAGGCGGGGGGGAGUUUUCAGUAUUUUUUUUUGUGGGGGUGGGGGCAAAAUAUGUUUUCAGUUCUUUUUCCCUUAGGUCUGUCUAGAAUCCUAAAGGCAAAUGACUCAAGGUGUAACAGAAAACAAGAAAAUCCAAUAUCAGGAUAAUCAGACCACCACAGGUUUACAGUUUAUAGAAACUAGAGCAGUUCUCACGUUGAGGUCUGUGGAAGAGAUGUCCAUUGGAGAAAUGGCUGGUAGUUACUCUUUUUUCCCCCCACCCCCUUAAUCAGACUUUAAAAGUGCUUAACCCCUUAAACUUGUUAUUUUUUACUUGAAGCAUUUUGGGAUGGUCUUAACAGGGAAGAGAGAGGGUGGGGGAGAAAAUGUUUUUUUCUAAGAUUUUCCACAGAUGCUAUAGUACUAUUGACAAACUGGGUUAGAGAAGGAGUGUACCGCUGUGCUGUUGGCACGAACACCUUCAGGGACUGGAGCUGCUUUUAUCCUUGGAAGAGUAUUCCCAGUUGAAGCUGAAAAGUACAGCACAGUGCAGCUUUGGUUCAUAUUCAGUCAUCUCAGGAGAACUUCAGAAGAGCUUGAGUAGGCCAAAUGUUGAAGUUAAGUUUUCCAAUAAUGUGACUUCUUAAAAGUUUUAUUAAAGGGGAGGGGCAAAUAUUGGCAAUUAGUUGGCAGUGGCCUGUUACGGUUGGGAUUGGUGGGGUGGGUUUAGGUAAUUGUUUAGUUUAUGAUUGCAGAUAAACUCAUGCCAGAGAACUUAAAGUCUUAGAAUGGAAAAAGUAAAGAAAUAUCAACUUCCAAGUUGGCAAGUAACUCCCAAUGAUUUAGUUUUUUUCCCCCCAGUUUGAAUUGGGAAGCUGGGGGAAGUUAAAUAUGAGCCACUGGGUGUACCAGUGCAUUAAUUUGGGCAAGGAAAGUGUCAUAAUUUGAUACUGUAUCUGUUUUCCUUCAAAGUAUAGAGCUUUUGGGGAAGGAAAGUAUUGAACUGGGGGUUGGUCUGGCCUACUGGGCUGACAUUAACUACAAUUAUGGGAAAUGCAAAAGUUGUUUGGAUAUGGUAGUGUGUGGUUCUCUUUUGGAAUUUUUUUCAGGUGAUUUAAUAAUAAUUUAAAACUACUAUAGAAACUGCAGAGCAAAGGAAGUGGCUUAAUGAUCCUGAAGGGAUUUCUUCUGAUGGUAGCUUUUGUAUUAUCAAGUAAGAUUCUAUUUUCAGUUGUGUGUAAGCAAGUUUUUUUUUAGUGUAGGAGAAAUACUUUUCCAUUGUUUAACUGCAAAACAAGAUGUUAAGGUAUGCUUCAAAAAUUUUGUAAAUUGUUUAUUUUAAACUUAUCUGUUUGUAAAUUGUAACUGAUUAAGAAUUGUGAUAGUUCAGCUUGAAUGUCUCUUAGAGGGUGGGCUUUUGUUGAUGAGGGAGGGGAAACUUUUUUUUUUUCUAUAGACUUUUUUCAGAUAACAUCUUCUGAGUCAUAACCAGCCUGGCAGUAUGAUGGCCUAGAUGCAGAGAAAACAGCUCCUUGGUGAAUUGAUAAGUAAAGGCAGAAAAGAUUAUAUGUCAUACCUCCAUUGGGGAAUAAGCAUAACCCUGAGAUUCUUACUACUGAUGAGAACAUUAUCUGCAUAUGCCAAAAAAUUUUAAGCAAAUGAAAGCUACCAAUUUAAAGUUACGGAAUCUACCAUUUUAAAGUUAAUUGCUUGUCAAGCUAUAACCACAAAAAUAAUGAAUUGAUGAGAAAUACAAUGAAGAGGCAAUGUCCAUCUCAAAAUACUGCUUUUACAAAAGCAGAAUAAAAGCGAAAAGAAAUGAAAAUGUUACACUACAUUAAUCCUGGAAUAAAAGAAGCCGAAAUAAAUGAGAGAUGAGUUGGGAUCAAGUGGAUUGAGGAGGCUGUGCUGUGUGCCAAUGUUUCGUUUGCCUCAGACAGGUAUCUCUUCGUUAUCAGAAGAGUUGCUUCAUUUCAUCUGGGAGCAGAAAACAGCAGGCAGCUGUUAACAGAUAAGUUUAACUUGCAUCUGCAGUAUUGCAUGUUAGGGAUAAGUGCUUAUUUUUAAGAGCUGUGGAGUUCUUAAAUAUCAACCAUGGCACUUUCUCCUGACCCCUUCCCUAGGGGAUUUCAGGAUUGAGAAAUUUUUCCAUCGAGCCUUUUUAAAAUUGUAGGACUUGUUCCUGUGGGCUUCAGUGAUGGGAUAGUACACUUCACUCAGAGGCAUUUGCAUCUUUAAAUAAUUUCUUAAAAGCCUCUAAAGUGAUCAGUGCCUUGAUGCCAACUAAGGAAAUUUGUUUAGCAUUGAAUCUCUGAAGGCUCUAUGAAAGGAAUAGCAUGAUGUGCUGUUAGAAUCAGAUGUUACUGCUAAAAUUUACAUGUUGUGAUGUAAAUUGUGUAGAAAACCAUUAAAUCAUUCAAAAUAAUAAACUAUUUUUAUUAGAGAAUGUAUACUUUUAGAAAGCUGUCUCCUUAUUUAAAUAAAAUAGUGUUUGUCUGUAGUUCAGUGUUGGGGCAAUCUUGGGGGGGAUUCUUCUCUAAUCUUUCAGAAACUUUGUCUGCGAACACUCUUUAAUGGACCAGAUCAGGAUUUGAGCGGAAGAACGAAUGUAACUUUAAGGCAGGAAAGACAAAUUUUAUUCUUCAUAAAGUGAUGAGCAUAUAAUAAUUCCAGGCACAUGGCAAUAGAGGCCCUCUAAAUAAGGAAUAAAUAACCUCUUAGACAGGUGGGAGAUUAUGAUCAGAGUAAAAGGUAAUUACACAUUUUAUUUCCAGAAAGUCAGGGGUCUAUAAAUUGACAGUGAUUAGAGUAAUACUUUUUCACAUUUCCAAAGUUUGCAUGUUAACUUUAAAUGCUUACAAUCUUAGAGUGGUAGGCAAUGUUUUACACUAUUGACCUUAUAUAGGGAAGGGAGGGGGUGCCUGUGGGGUUUUAAAGAAUUUUCCUUUGCAGAGGCAUUUCAUCCUUCAUGAAGCCAUUCAGGAUUUUGAAUUGCAUAUGAGUGCUUGGCUCUUCCUUCUGUUCUAGUGAGUGUAUGAGACCUUGCAGUGAGUUUAUCAGCAUACUCAAAAUUUUUUUCCUGGAAUUUGGAGGGAUGGGAGGAGGGGGUGGGGCUUACUUGUUGUAGCUUUUUUUUUUUUUACAGACUUCACAGAGAAUGCAGUUGUCUUGACUUCAGGUCUGUCUGUUCUGUUGGCAAGUAAAUGCAGUACUGUUCUGAUCCCGCUGCUAUUAGAAUGCAUUGUGAAACGACUGGAGUAUGAUUAAAAGUUGUGUUCCCCAAUGCUUGGAGUAGUGAUUGUUGAAGGAAAAAAUCCAGCUGAGUGAUAAAGGCUGAGUGUUGAGGAAAUUUCUGCAGUUUUAAGCAGUCGUAUUUGUGAUUGAAGCUGAGUACAUUUUGCUGGUGUAUUUUUAGGUAAAAUGCUUUUUGUUCAUUUCUGGUGGUGGGAGGGGACUGAAGCCUUUAGUCUUUUCCAGAUGCAACCUUAAAAUCAGUGACAAGAAACAUUCCAAACAAGCAACAGUCUUCAAGAAAUUAAACUGGCAAGUGGAAAUGUUUAAACAGUUCAGUGAUCUUUAGUGCAUUGUUUAUGUGUGGGUUUCUCUCUCCCCUCCCUUGGUCUUAAUUCUUACAUGCAGGAACACUCAGCAGACACACGUAUGCGAAGGGCCAGAGAAGCCAGACCCAGUAAGAAAAAAUAGCCUAUUUACUUUAAAUAAACCAAACAUUCCAUUUUAAAUGUGGGGAUUGGGAACCACUAGUUCUUUCAGAUGGUAUUCUUCAGACUAUAGAAGGAGCUUCCAGUUGAAUUCACCAGUGGACAAAAUGAGGAAAACAGGUGAACAAGCUUUUUCUGUAUUUACAUACAAAGUCAGAUCAGUUAUGGGACAAUAGUAUUGAAUAGAUUUCAGCUUUAUGCUGGAGUAACUGGCAUGUGAGCAAACUGUGUUGGCGUGGGGGUGGAGGGGUGAGGUGGGCGCUAAGCCUUUUUUUAAGAUUUUUCAGGUACCCCUCACUAAAGGCACCGAAGGCUUAAAGUAGGACAACCAUGGAGCCUUCCUGUGGCAGGAGAGACAACAAAGCGCUAUUAUCCUAAGGUCAAGAGAAGUGUCAGCCUCACCUGAUUUUUAUUAGUAAUGAGGACUUGCCUCAACUCCCUCUUUCUGGAGUGAAGCAUCCGAAGGAAUGCUUGAAGUACCCCUGGGCUUCUCUUAACAUUUAAGCAAGCUGUUUUUAUAGCAGCUCUUAAUAAUAAAGCCCAAAUCUCAAGCGGUGCUUGAAGGGGAGGGAAAGGGGGAAAGCGGGCAACCACUUUUCCCUAGCUUUUCCAGAAGCCUGUUAAAAGCAAGGUCUCCCCACAAGCAACUUCUCUGCCACAUCGCCACCCCGUGCCUUUUGAUCUAGCACAGACCCUUCACCCCUCACCUCGAUGCAGCCAGUAGCUUGGAUCCUUGUGGGCAUGAUCCAUAAUCGGUUUCAAGGUAACGAUGGUGUCGAGGUCUUUGGUGGGUUGAACUAUGUUAGAAAAGGCCAUUAAUUUGCCUGCAAAUUGUUAACAGAAGGGUAUUAAAACCACAGCUAAGUAGCUCUAUUAUAAUACUUAUCCAGUGACUAAAACCAACUUAAACCAGUAAGUGGAGAAAUAACAUGUUCAAGAACUGUAAUGCUGGGUGGGAACAUGUAACUUGUAGACUGGAGAAGAUAGGCAUUUGAGUGGCUGAGAGGGCUUUUGGGUGGGAAUGCAAAAAUUCUCUGCUAAGACUUUUUCAGGUGAACAUAACAGACUUGGCCAAGCUAGCAUCUUAGCGGAAGCUGAUCUCCAAUGCUCUUCAGUAGGGUCAUGAAGGUUUUUCUUUUCCUGAGAAAACAACACGUAUUGUUUUCUCAGGUUUUGCUUUUUGGCCUUUUUCUAGCUUAAAAAAAAAAAAAGCAAAAGAUGCUGGUGGUUGGCACUCCUGGUUUCCAGGACGGGGUUCAAAUCCCUGCGGCGUCUUUGCUUUGACUACUAAUCUGUCUUCAGGACUCUUUCUGUAUUUCUCCUUUUCUCUGCAGGUGCUAGUUCUUGGAGUUUUGGGGAGGUGGGAGGUAACAGCACAAUAUCUUUGAACUAUAUACAUCCUUGAUGUAUAAUUUGUCAGGAGCUUGACUUGAUUGUAUAUUCAUAUUUACACGAGAACCUAAUAUAACUGCCUUGUCUUUUUCAGGUAAUAGCCUGCAGCUGGUGUUUUGAGAAGCCCUACUGCUGAAAACUUAACAAUUUUGUGUAAUAAAAAUGGAGAAGCUCUAAAUUGUUGUGGUUCUUUUGUGAAUAAAAAAAUCUUGAUUGGGGAAAAAA malat1-snrna u2_1-1 3 13 unspecified role unspecified role neutral component neutral component physiological level physiological level endogenous level endogenous endogenous endogenous level fixed cell fixed cell 10 antibody detection identification by antibody antibody detection immunocytochemistry immunocytochemistry unspecified role unspecified role neutral component neutral component physiological level physiological level endogenous level endogenous endogenous endogenous level fixed cell fixed cell 15 unspecified role unspecified role neutral component neutral component physiological level physiological level endogenous level endogenous endogenous endogenous level fixed cell fixed cell colocalization colocalization Fig 1A srsf1-lncrn_malat1 human-3 4 10 anti tag immunost anti tag immunostaining anti tag immunost q-pcr quantitative pcr q-pcr unspecified role unspecified role bait bait over-expressed over expressed level over-expressed living cell living cell engineered engineered region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain tag t7 tag t7 tag MASMTGGQQMG epitope tag MASMTGGQQMG epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range p.[Phe56Asp;Phe58Asp] mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing certain certain sequence position certain certain certain sequence position certain F D certain certain sequence position certain certain certain sequence position certain F D The deletion is in the RRM1 domain 15 unspecified role unspecified role prey prey living cell living cell physiological level physiological level endogenous level endogenous endogenous endogenous level physical association physical association Fig 1 C, D srsf2-lncrn_malat1 human-1 4 9 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed living cell living cell engineered engineered tag t7 tag t7 tag MASMTGGQQMG epitope tag MASMTGGQQMG epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range 15 unspecified role unspecified role prey prey living cell living cell physiological level physiological level endogenous level endogenous endogenous endogenous level physical association physical association Fig 1 C srsf5-lncrn_malat1 human-1 4 15 unspecified role unspecified role prey prey living cell living cell physiological level physiological level endogenous level endogenous endogenous endogenous level 11 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed living cell living cell engineered engineered physical association physical association Fg 1 C srsf1-lncrn_malat1 human-2 1 10 anti tag immunost anti tag immunostaining anti tag immunost rt-pcr reverse transcription pcr RT-PCR unspecified role unspecified role bait bait living cell living cell physiological level physiological level endogenous level endogenous endogenous endogenous level 15 unspecified role unspecified role prey prey living cell living cell physical association physical association Fig 1B lncrn_neat1 human-pspc1-1 4 7 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed living cell living cell engineered engineered tag t7 tag t7 tag MASMTGGQQMG epitope tag MASMTGGQQMG epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range 5 unspecified role unspecified role prey prey living cell living cell physiological level physiological level endogenous level endogenous endogenous endogenous level physical association physical association Fig 1 C srsf1-lncrn_malat1 human-4 1 10 anti tag immunost anti tag immunostaining anti tag immunost rt-pcr reverse transcription pcr RT-PCR unspecified role unspecified role bait bait over-expressed over expressed level over-expressed living cell living cell engineered engineered tag t7 tag t7 tag MASMTGGQQMG epitope tag MASMTGGQQMG epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range 15 unspecified role unspecified role prey prey living cell living cell physiological level physiological level endogenous level endogenous endogenous endogenous level physical association physical association Suppl Fig 1B, C; Fig 3C srsf2-lncrn_malat1 human-2 1 9 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed living cell living cell engineered engineered tag t7 tag t7 tag MASMTGGQQMG epitope tag MASMTGGQQMG epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range 15 unspecified role unspecified role prey prey living cell living cell physiological level physiological level endogenous level endogenous endogenous endogenous level physical association physical association Suppl Fig 1B, C srsf5-lncrn_malat1 human-2 1 15 unspecified role unspecified role prey prey living cell living cell physiological level physiological level endogenous level endogenous endogenous endogenous level 11 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed living cell living cell engineered engineered physical association physical association Suppl Fig 1B, C srsf3-lncrn_malat1 human-1 1 12 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed living cell living cell engineered engineered tag t7 tag t7 tag MASMTGGQQMG epitope tag MASMTGGQQMG epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range 15 unspecified role unspecified role prey prey living cell living cell physiological level physiological level endogenous level endogenous endogenous endogenous level physical association physical association Suppl Fig 1B, C srsf1-lncrn_malat1 human-5 4 10 anti tag immunost anti tag immunostaining anti tag immunost q-pcr quantitative pcr q-pcr unspecified role unspecified role bait bait living cell living cell physiological level physiological level endogenous level endogenous endogenous endogenous level 15 unspecified role unspecified role prey prey living cell living cell physical association physical association Fig 1Bc lncrn_malat1 mouse-srsf1-1 2 10 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed fixed cell fixed cell Tag eyfp enhanced yellow fluorescent protein tag eyfp n-term range n-terminal range n-term range n-term range n-terminal range n-term range 14 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed engineered engineered fixed cell fixed cell region binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain region binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain colocalization colocalization Fig 2C prpf6-lncrn_malat1 human-1 1 15 unspecified role unspecified role prey prey living cell living cell physiological level physiological level endogenous level endogenous endogenous endogenous level 6 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed living cell living cell tag t7 tag t7 tag MASMTGGQQMG epitope tag MASMTGGQQMG epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range physical association physical association Fig 3 C srsf1-lncrn_malat1 mouse-2 4 14 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 8 unspecified role unspecified role bait bait physiological level physiological level endogenous level endogenous endogenous endogenous level physical association physical association Suppl fig 2 A lncrn_malat1 human-srsf1-1 2 15 unspecified role unspecified role neutral component neutral component physiological level physiological level endogenous level endogenous endogenous endogenous level fixed cell fixed cell 10 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed fixed cell fixed cell tag eyfp enhanced yellow fluorescent protein tag eyfp n-term range n-terminal range n-term range n-term range n-terminal range n-term range colocalization colocalization Fig 3B, D; Suppl Fig3C,E Silencing Prp6 or Son genes diminishes the colocalization lncrn_malat1 human-srsf2-1 2 9 unspecified role unspecified role unspecified role unspecified role over-expressed over expressed level over-expressed fixed cell fixed cell tag rfp tag red fluorescent protein tag red fluorescent protein RFP red fluorescent protein RFP rfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 15 unspecified role unspecified role neutral component neutral component physiological level physiological level endogenous level endogenous endogenous endogenous level fixed cell fixed cell colocalization colocalization Fig 3A Silencing srsf1 genes does not influence the colocalization lncrn_malat1 human-prpf6-1 4 6 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed living cell living cell tag t7 tag t7 tag MASMTGGQQMG epitope tag MASMTGGQQMG epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range 15 unspecified role unspecified role prey prey physiological level physiological level endogenous level endogenous endogenous endogenous level physical association physical association Suppl Fig 3D prpf6-lncrn_malat1 human-2 4 14 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed 6 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed living cell living cell tag t7 tag t7 tag MASMTGGQQMG epitope tag MASMTGGQQMG epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range physical association physical association Suppl Fig 3D