DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Activation of NMDA receptors and the mechanism of inhibition by ifenprodil. Activation of NMDA receptors and the mechanism of inhibition by ifenprodil. Nature 2016 imex curation Tajima N., Karakas E., Grant T., Simorowski N., Diaz-Avalos R., Grigorieff N., Furukawa H. Only protein-protein interactions spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm crosslink cross-linking study crosslink predetermined predetermined participant predetermined Tajima N., Karakas E., Grant T., Simorowski N., Diaz-Avalos R., Grigorieff N., Furukawa H. DIP original experiment: DIP-269083X Nature 2016 IMEx Activation of NMDA receptors and the mechanism of inhibition by ifenprodil. Activation of NMDA receptors and the mechanism of inhibition by ifenprodil. Activation of NMDA receptors and the mechanism of inhibition by ifenprodil. Nature 2016 imex curation Tajima N., Karakas E., Grant T., Simorowski N., Diaz-Avalos R., Grigorieff N., Furukawa H. Only protein-protein interactions spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm 3d-em 3D electron microscopy 3D-EM electron tomog predetermined predetermined participant predetermined Tajima N., Karakas E., Grant T., Simorowski N., Diaz-Avalos R., Grigorieff N., Furukawa H. DIP original experiment: DIP-269082X Nature 2016 IMEx Activation of NMDA receptors and the mechanism of inhibition by ifenprodil. Activation of NMDA receptors and the mechanism of inhibition by ifenprodil. Activation of NMDA receptors and the mechanism of inhibition by ifenprodil. Nature 2016 imex curation Tajima N., Karakas E., Grant T., Simorowski N., Diaz-Avalos R., Grigorieff N., Furukawa H. Only protein-protein interactions trini Trichoplusia ni (Cabbage looper) Cabbage looper x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Tajima N., Karakas E., Grant T., Simorowski N., Diaz-Avalos R., Grigorieff N., Furukawa H. DIP original experiment: DIP-269081X Nature 2016 IMEx Activation of NMDA receptors and the mechanism of inhibition by ifenprodil. Activation of NMDA receptors and the mechanism of inhibition by ifenprodil. Activation of NMDA receptors and the mechanism of inhibition by ifenprodil. Nature 2016 imex curation Tajima N., Karakas E., Grant T., Simorowski N., Diaz-Avalos R., Grigorieff N., Furukawa H. Only protein-protein interactions spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm crosslink cross-linking study crosslink predetermined predetermined participant predetermined Tajima N., Karakas E., Grant T., Simorowski N., Diaz-Avalos R., Grigorieff N., Furukawa H. DIP original experiment: DIP-269084X Nature 2016 IMEx Activation of NMDA receptors and the mechanism of inhibition by ifenprodil. nmde2_rat Glutamate receptor ionotropic, NMDA 2B Grin2b Glutamate [NMDA] receptor subunit epsilon-2 N-methyl D-aspartate receptor subtype 2B protein protein rat Rattus norvegicus (Rat) Rat MKPSAECCSPKFWLVLAVLAVSGSKARSQKSPPSIGIAVILVGTSDEVAIKDAHEKDDFHHLSVVPRVELVAMNETDPKSIITRICDLMSDRKIQGVVFADDTDQEAIAQILDFISAQTLTPILGIHGGSSMIMADKDESSMFFQFGPSIEQQASVMLNIMEEYDWYIFSIVTTYFPGYQDFVNKIRSTIENSFVGWELEEVLLLDMSLDDGDSKIQNQLKKLQSPIILLYCTKEEATYIFEVANSVGLTGYGYTWIVPSLVAGDTDTVPSEFPTGLISVSYDEWDYGLPARVRDGIAIITTAASDMLSEHSFIPEPKSSCYNTHEKRIYQSNMLNRYLINVTFEGRNLSFSEDGYQMHPKLVIILLNKERKWERVGKWKDKSLQMKYYVWPRMCPETEEQEDDHLSIVTLEEAPFVIVESVDPLSGTCMRNTVPCQKRIISENKTDEEPGYIKKCCKGFCIDILKKISKSVKFTYDLYLVTNGKHGKKINGTWNGMIGEVVMKRAYMAVGSLTINEERSEVVDFSVPFIETGISVMVSRSNGTVSPSAFLEPFSADVWVMMFVMLLIVSAVAVFVFEYFSPVGYNRCLADGREPGGPSFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEYVDQVSGLSDKKFQRPNDFSPPFRFGTVPNGSTERNIRNNYAEMHAYMGKFNQRGVDDALLSLKTGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSGKVFASTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELEALWLTGICHNEKNEVMSSQLDIDNMAGVFYMLGAAMALSLITFICEHLFYWQFRHCFMGVCSGKPGMVFSISRGIYSCIHGVAIEERQSVMNSPTATMNNTHSNILRLLRTAKNMANLSGVNGSPQSALDFIRRESSVYDISEHRRSFTHSDCKSYNNPPCEENLFSDYISEVERTFGNLQLKDSNVYQDHYHHHHRPHSIGSTSSIDGLYDCDNPPFTTQPRSISKKPLDIGLPSSKHSQLSDLYGKFSFKSDRYSGHDDLIRSDVSDISTHTVTYGNIEGNAAKRRKQQYKDSLKKRPASAKSRREFDEIELAYRRRPPRSPDHKRYFRDKEGLRDFYLDQFRTKENSPHWEHVDLTDIYKERSDDFKRDSVSGGGPCTNRSHLKHGTGEKHGVVGGVPAPWEKNLTNVDWEDRSGGNFCRSCPSKLHNYSSTVAGQNSGRQACIRCEACKKAGNLYDISEDNSLQELDQPAAPVAVTSNASSTKYPQSPTNSKAQKKNRNKLRRQHSYDTFVDLQKEEAALAPRSVSLKDKGRFMDGSPYAHMFEMPAGESSFANKSSVPTAGHHHNNPGSGYMLSKSLYPDRVTQNPFIPTFGDDQCLLHGSKSYFFRQPTVAGASKTRPDFRALVTNKPVVVTLHGAVPGRFQKDICIGNQSNPCVPNNKNPRAFNGSSNGHVYEKLSSIESDV DIP protein Q00960 original sequence version: 102 DIP protein Q00960 original sequence version: 113 DIP protein Q00960 original sequence version: 148 DIP protein Q00960 original sequence version: 158 AEF8B9DF3C1B0D5D a0a1l8f5j9-8 Glutamate receptor ionotropic, NMDA 1 grin1 N-methyl-D-aspartate receptor subunit NR1 protein protein xenla Xenopus laevis (African clawed frog) African clawed frog MGTMRLFLLAVLFLFSFARAGCDPKIVNIGAVLSTKKHEQIFREAVNQANKRHFTRKIQLNATSVTHRPNAIQMALSVCEDLISSQVYAILVSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTVPPYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEGKESKSKKRNYENLDQLSYDNKRGPKADKVLQFEPGTKNLTALLLEAKELEARVIILSASEDDATAVYKSAAMLDMTGAGYVWLVGEREISGSALRYAPDGIIGLQLINGKNESAHISDAVAVVAQAIHELFEMENITDPPRGCVGNTNIWKTGPLFKRVLMSSKYPDGVTGRIEFNEDGDRKFANYSIMNLQNRKLVQVGIFNGSYIIQNDRKIIWPGGETERPQGYQMSTRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPNETIPGRPTVPQCCYGFCVDLLIKLAREMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRFSPFGRFKVNSEEEEEDALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLNILKSHENGFMEELDKTWVRYQECDSRSNAPATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRHKDARRKQMQLAFAAVNVWRKNLQQYPPTDITGQLNLSDPSVSTVV nmdz1_rat Glutamate receptor ionotropic, NMDA 1 N-methyl-D-aspartate receptor subunit NR1 Grin1 Nmdar1 Glutamate [NMDA] receptor subunit zeta-1 protein protein rat Rattus norvegicus (Rat) Rat MSTMHLLTFALLFSCSFARAACDPKIVNIGAVLSTRKHEQMFREAVNQANKRHGSWKIQLNATSVTHKPNAIQMALSVCEDLISSQVYAILVSHPPTPNDHFTPTPVSYTAGFYRIPVLGLTTRMSIYSDKSIHLSFLRTVPPYSHQSSVWFEMMRVYNWNHIILLVSDDHEGRAAQKRLETLLEERESKAEKVLQFDPGTKNVTALLMEARELEARVIILSASEDDAATVYRAAAMLNMTGSGYVWLVGEREISGNALRYAPDGIIGLQLINGKNESAHISDAVGVVAQAVHELLEKENITDPPRGCVGNTNIWKTGPLFKRVLMSSKYADGVTGRVEFNEDGDRKFANYSIMNLQNRKLVQVGIYNGTHVIPNDRKIIWPGGETEKPRGYQMSTRLKIVTIHQEPFVYVKPTMSDGTCKEEFTVNGDPVKKVICTGPNDTSPGSPRHTVPQCCYGFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRFSPFGRFKVNSEEEEEDALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLSILKSHENGFMEDLDKTWVRYQECDSRSNAPATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRHKDARRKQMQLAFAAVNVWRKNLQDRKSGRAEPDPKKKATFRAITSTLASSFKRRRSSKDTSTGGGRGALQNQKDTVLPRRAIEREEGQLQLCSRHRES DIP protein P35439 original sequence version: 164 DIP protein P35439-1 original sequence version: 120 DIP protein P35439 original sequence version: 130 DIP protein P35439 original sequence version: 147 DIP protein P35439 original sequence version: 171 DIP protein P35439 original sequence version: 183 613D36E38F05BC73 grin1-grin2b-16 1 5 unspecified role unspecified role unspecified role unspecified role Region 31-394 Region 31-394 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain Q00960:p.Ala107Cys A107C mutation mutation certain certain sequence position certain certain certain sequence position certain A C This feature has been corrected as a result of our quality control procedures. The original label was 'A107C'. Wed May 02 14:36:00 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ala107cys' Tue Jun 30 18:35:19 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ala107Cys' spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm 6 unspecified role unspecified role unspecified role unspecified role Region 23-408 Region 23-408 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain A0A1L8F5J9-8:p.Phe113Cys F113C mutation mutation certain certain sequence position certain certain certain sequence position certain F C This feature has been corrected as a result of our quality control procedures. The original label was 'F113C'. Wed May 02 14:55:19 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe113cys' Tue Jun 30 20:02:02 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Phe113Cys' spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm physical association physical association grin1-grin2b-17 3 5 unspecified role unspecified role unspecified role unspecified role Region 31-394 Region 31-394 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain trini Trichoplusia ni (Cabbage looper) Cabbage looper 6 unspecified role unspecified role unspecified role unspecified role Region 23-405 Region 23-405 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain trini Trichoplusia ni (Cabbage looper) Cabbage looper direct interaction direct interaction grin1-grin2b-18 2 7 unspecified role unspecified role unspecified role unspecified role Region 23-868 Region 23-868 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm 5 unspecified role unspecified role unspecified role unspecified role Region 27-852 Region 27-852 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm direct interaction direct interaction grin1-grin2b-19 4 5 unspecified role unspecified role unspecified role unspecified role Region 31-394 Region 31-394 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain Q00960:p.Glu75Cys E75C mutation mutation certain certain sequence position certain certain certain sequence position certain E C This feature has been corrected as a result of our quality control procedures. The original label was 'E75C'. Wed May 02 15:51:41 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'glu75cys' Tue Jun 30 18:17:22 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Glu75Cys' spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm 6 unspecified role unspecified role unspecified role unspecified role Region 23-408 Region 23-408 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain A0A1L8F5J9-8:p.Gly331Cys G331C mutation mutation certain certain sequence position certain certain certain sequence position certain G C This feature has been corrected as a result of our quality control procedures. The original label was 'G331C'. Wed May 02 16:39:22 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'gly331cys' Tue Jun 30 18:01:54 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Gly331Cys' spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm physical association physical association