DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture. SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture. Nature cell biology 2016 imex curation Hilbert M., Noga A., Frey D., Hamel V., Guichard P., Kraatz SH., Pfreundschuh M., Hosner S., Flückiger I., Jaussi R., Wieser MM., Thieltges KM., Deupi X., Müller DJ., Kammerer RA., Gönczy P., Hirono M., Steinmetz MO. Only protein-protein interactions ecolx Escherichia coli crosslink cross-linking study crosslink weight by comassie molecular weight estimation by coomasie staining weight by comassie Hilbert M., Noga A., Frey D., Hamel V., Guichard P., Kraatz SH., Pfreundschuh M., Hosner S., Flückiger I., Jaussi R., Wieser MM., Thieltges KM., Deupi X., Müller DJ., Kammerer RA., Gönczy P., Hirono M., Steinmetz MO. DIP original experiment: DIP-268973X Nature cell biology 2016 IMEx SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture. SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture. SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture. Nature cell biology 2016 imex curation Hilbert M., Noga A., Frey D., Hamel V., Guichard P., Kraatz SH., Pfreundschuh M., Hosner S., Flückiger I., Jaussi R., Wieser MM., Thieltges KM., Deupi X., Müller DJ., Kammerer RA., Gönczy P., Hirono M., Steinmetz MO. Only protein-protein interactions ecolx Escherichia coli crosslink cross-linking study crosslink weight by comassie molecular weight estimation by coomasie staining weight by comassie Hilbert M., Noga A., Frey D., Hamel V., Guichard P., Kraatz SH., Pfreundschuh M., Hosner S., Flückiger I., Jaussi R., Wieser MM., Thieltges KM., Deupi X., Müller DJ., Kammerer RA., Gönczy P., Hirono M., Steinmetz MO. DIP original experiment: DIP-268972X Nature cell biology 2016 IMEx SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture. SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture. SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture. Nature cell biology 2016 imex curation Hilbert M., Noga A., Frey D., Hamel V., Guichard P., Kraatz SH., Pfreundschuh M., Hosner S., Flückiger I., Jaussi R., Wieser MM., Thieltges KM., Deupi X., Müller DJ., Kammerer RA., Gönczy P., Hirono M., Steinmetz MO. Only protein-protein interactions ecolx Escherichia coli fps fluorescence polarization spectroscopy Fluorescence anisotropy FPS FPS Fluorescence anisotropy fps predetermined predetermined participant predetermined Hilbert M., Noga A., Frey D., Hamel V., Guichard P., Kraatz SH., Pfreundschuh M., Hosner S., Flückiger I., Jaussi R., Wieser MM., Thieltges KM., Deupi X., Müller DJ., Kammerer RA., Gönczy P., Hirono M., Steinmetz MO. DIP original experiment: DIP-268970X Nature cell biology 2016 IMEx SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture. SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture. SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture. Nature cell biology 2016 imex curation Hilbert M., Noga A., Frey D., Hamel V., Guichard P., Kraatz SH., Pfreundschuh M., Hosner S., Flückiger I., Jaussi R., Wieser MM., Thieltges KM., Deupi X., Müller DJ., Kammerer RA., Gönczy P., Hirono M., Steinmetz MO. Only protein-protein interactions ecolx Escherichia coli solution sedimentati cosedimentation in solution solution sedimentati predetermined predetermined participant predetermined Hilbert M., Noga A., Frey D., Hamel V., Guichard P., Kraatz SH., Pfreundschuh M., Hosner S., Flückiger I., Jaussi R., Wieser MM., Thieltges KM., Deupi X., Müller DJ., Kammerer RA., Gönczy P., Hirono M., Steinmetz MO. DIP original experiment: DIP-268968X Nature cell biology 2016 IMEx SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture. SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture. SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture. Nature cell biology 2016 imex curation Hilbert M., Noga A., Frey D., Hamel V., Guichard P., Kraatz SH., Pfreundschuh M., Hosner S., Flückiger I., Jaussi R., Wieser MM., Thieltges KM., Deupi X., Müller DJ., Kammerer RA., Gönczy P., Hirono M., Steinmetz MO. Only protein-protein interactions ecolx Escherichia coli tem transmission electron microscopy tem predetermined predetermined participant predetermined Hilbert M., Noga A., Frey D., Hamel V., Guichard P., Kraatz SH., Pfreundschuh M., Hosner S., Flückiger I., Jaussi R., Wieser MM., Thieltges KM., Deupi X., Müller DJ., Kammerer RA., Gönczy P., Hirono M., Steinmetz MO. DIP original experiment: DIP-268971X Nature cell biology 2016 IMEx SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture. SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture. SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture. Nature cell biology 2016 imex curation Hilbert M., Noga A., Frey D., Hamel V., Guichard P., Kraatz SH., Pfreundschuh M., Hosner S., Flückiger I., Jaussi R., Wieser MM., Thieltges KM., Deupi X., Müller DJ., Kammerer RA., Gönczy P., Hirono M., Steinmetz MO. Only protein-protein interactions ecolx Escherichia coli x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Hilbert M., Noga A., Frey D., Hamel V., Guichard P., Kraatz SH., Pfreundschuh M., Hosner S., Flückiger I., Jaussi R., Wieser MM., Thieltges KM., Deupi X., Müller DJ., Kammerer RA., Gönczy P., Hirono M., Steinmetz MO. DIP original experiment: DIP-268975X Nature cell biology 2016 IMEx SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture. SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture. SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture. Nature cell biology 2016 imex curation Hilbert M., Noga A., Frey D., Hamel V., Guichard P., Kraatz SH., Pfreundschuh M., Hosner S., Flückiger I., Jaussi R., Wieser MM., Thieltges KM., Deupi X., Müller DJ., Kammerer RA., Gönczy P., Hirono M., Steinmetz MO. Only protein-protein interactions ecolx Escherichia coli atomic force microsc atomic force microscopy AFM AFM atomic force microsc predetermined predetermined participant predetermined Hilbert M., Noga A., Frey D., Hamel V., Guichard P., Kraatz SH., Pfreundschuh M., Hosner S., Flückiger I., Jaussi R., Wieser MM., Thieltges KM., Deupi X., Müller DJ., Kammerer RA., Gönczy P., Hirono M., Steinmetz MO. DIP original experiment: DIP-268967X Nature cell biology 2016 IMEx SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture. SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture. SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture. Nature cell biology 2016 imex curation Hilbert M., Noga A., Frey D., Hamel V., Guichard P., Kraatz SH., Pfreundschuh M., Hosner S., Flückiger I., Jaussi R., Wieser MM., Thieltges KM., Deupi X., Müller DJ., Kammerer RA., Gönczy P., Hirono M., Steinmetz MO. Only protein-protein interactions ecolx Escherichia coli itc isothermal titration calorimetry ITC ITC itc predetermined predetermined participant predetermined Hilbert M., Noga A., Frey D., Hamel V., Guichard P., Kraatz SH., Pfreundschuh M., Hosner S., Flückiger I., Jaussi R., Wieser MM., Thieltges KM., Deupi X., Müller DJ., Kammerer RA., Gönczy P., Hirono M., Steinmetz MO. DIP original experiment: DIP-268969X Nature cell biology 2016 IMEx SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture. SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture. SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture. Nature cell biology 2016 imex curation Hilbert M., Noga A., Frey D., Hamel V., Guichard P., Kraatz SH., Pfreundschuh M., Hosner S., Flückiger I., Jaussi R., Wieser MM., Thieltges KM., Deupi X., Müller DJ., Kammerer RA., Gönczy P., Hirono M., Steinmetz MO. Only protein-protein interactions ecolx Escherichia coli crosslink cross-linking study crosslink weight by comassie molecular weight estimation by coomasie staining weight by comassie Hilbert M., Noga A., Frey D., Hamel V., Guichard P., Kraatz SH., Pfreundschuh M., Hosner S., Flückiger I., Jaussi R., Wieser MM., Thieltges KM., Deupi X., Müller DJ., Kammerer RA., Gönczy P., Hirono M., Steinmetz MO. DIP original experiment: DIP-268974X Nature cell biology 2016 IMEx SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture. a9cql4_chlre CrSAS-6 CHLRE_12g516950v5 protein protein chlre Chlamydomonas reinhardtii Chlamydomonas smithii MPLLLDDGDPKAQTGFDLSTATTLFWRPVPVHVKQQDREDVLEELTFRILTGVAKQNHNLRILRIHISSDSDLFFLHTLEVSEEDFQSLKNDQGILVDFASFPGKIISLLEKCILAQPGDSPRFQAVLTIRGGESVFKIVEINDFKQLPHITLAFRPGNDSVVKQFLAFRLSEVKGTCHDLSDDLSRTRDDRDSMVAQLAQCRQQLAQLREQYDKHLLEVQAQAKTQQASAHEERIREKSQLKDQFEKERGEMEGRYRDQIAALNTRLGELDTENRKLREVKYELDTKVSELSHKLGSSEGSNRSLEEETARLRSLNQQLSSSKHELEIQLNEAKAKVLALDEKAQSQGDVIEQQRGRLRDMEAALRQTEQRCADLRDTLASAEGRAKEAQAEVLKGNQAIEKLTNDLRLAKEKTKRKAAIILRQEEELQEREQSLANATRDVGVLGQQAESLRKDVASLHSENDSLRSKLEDSKQQLQSNEQMIRWLNQQVTEAQLHASGATVAGSRYAFRPSAALPGSMPPPSVAATPAVGLLAAPGPSTAYKPGGTTSRYASTLGVTGLSSGLSGAGATSVGAAVAGGSYGAGGDSSYRPGVGGAYASSGGAGGFGGSVGGGGQVGGSGSAIGAATGAGSALGTYRSSYAASTHPSPGGVTAGMGSTLTTPAVNRYAAGSYSSVSSSLSFGGGLGAARAVDATPAASKYGVGFSNAAMGVVGTVGGAGGTDAQRA DIP protein A9CQL4 original sequence version: 30 55E067FF0454D96B crsas_6-1 7 10 unspecified role unspecified role unspecified role unspecified role Region 1-503 Region 1-503 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction crsas_6-2 8 10 unspecified role unspecified role unspecified role unspecified role Region 1-159 Region 1-159 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain A9CQL4:p.Ile95Phe I95F mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain I F This feature has been corrected as a result of our quality control procedures. The original label was 'I95F'. Wed May 02 16:19:39 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ile95phe' Tue Jun 30 16:35:28 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ile95Phe' A9CQL4:p.[Ile95Val;Phe102Trp] I95V/F102W mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain I V certain certain sequence position certain certain certain sequence position certain F W This feature has been corrected as a result of our quality control procedures. The original label was 'I95V/F102W'. Wed May 02 15:48:54 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ile95val,phe102trp' Tue Jun 30 19:53:06 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Ile95Val;Phe102Trp]' A9CQL4:p.[Phe102Trp;Phe145Tyr] F102W/F145Y mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain F Y certain certain sequence position certain certain certain sequence position certain F W This feature has been corrected as a result of our quality control procedures. The original label was 'F102W/F145Y'. Wed May 02 15:16:13 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe102trp,phe145tyr' Tue Jun 30 18:25:35 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Phe102Trp;Phe145Tyr]' A9CQL4:p.Lys105Arg K105R mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain K R This feature has been corrected as a result of our quality control procedures. The original label was 'K105R'. Wed May 02 14:53:17 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'lys105arg' Tue Jun 30 16:40:14 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Lys105Arg' A9CQL4:p.[Lys105Arg;Asp144Glu] K105R/D144E mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain D E certain certain sequence position certain certain certain sequence position certain K R This feature has been corrected as a result of our quality control procedures. The original label was 'K105R/D144E'. Wed May 02 14:29:08 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'lys105arg,asp144glu' Tue Jun 30 19:50:55 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Lys105Arg;Asp144Glu]' A9CQL4:p.Asn143Arg N143R mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain N R This feature has been corrected as a result of our quality control procedures. The original label was 'N143R'. Wed May 02 18:40:43 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'asn143arg' Tue Jun 30 19:12:04 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Asn143Arg' A9CQL4:p.[Gly94Glu;Gln147Arg] G94E/Q147R mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain G E certain certain sequence position certain certain certain sequence position certain Q R This feature has been corrected as a result of our quality control procedures. The original label was 'G94E/Q147R'. Wed May 02 14:38:26 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'gly94glu,gln147arg' Tue Jun 30 17:11:53 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Gly94Glu;Gln147Arg]' A9CQL4:p.[Gly94Cys;Lys146Cys] G94C/K146C mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain G C certain certain sequence position certain certain certain sequence position certain K C This feature has been corrected as a result of our quality control procedures. The original label was 'G94C/K146C'. Wed May 02 20:17:01 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'gly94cys,lys146cys' Tue Jun 30 18:33:01 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Gly94Cys;Lys146Cys]' ecolx Escherichia coli direct interaction direct interaction crsas_6-3 3 10 unspecified role unspecified role unspecified role unspecified role Region 1-159 Region 1-159 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction crsas_6-4 1 10 unspecified role unspecified role unspecified role unspecified role Region 1-159 Region 1-159 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain A9CQL4:p.[Gly94Cys;Lys146Cys] G94C/K146C mutation mutation certain certain sequence position certain certain certain sequence position certain G C certain certain sequence position certain certain certain sequence position certain K C This feature has been corrected as a result of our quality control procedures. The original label was 'G94C/K146C'. Wed May 02 16:52:51 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'gly94cys,lys146cys' Tue Jun 30 19:56:36 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Gly94Cys;Lys146Cys]' ecolx Escherichia coli direct interaction direct interaction crsas_6-5 9 10 unspecified role unspecified role unspecified role unspecified role Region 1-159 Region 1-159 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain A9CQL4:p.[Ile95Cys;Lys146Cys] I95C/K146C mutation mutation certain certain sequence position certain certain certain sequence position certain I C certain certain sequence position certain certain certain sequence position certain K C This feature has been corrected as a result of our quality control procedures. The original label was 'I95C/K146C'. Wed May 02 19:41:00 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ile95cys,lys146cys' Tue Jun 30 20:01:07 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Ile95Cys;Lys146Cys]' ecolx Escherichia coli direct interaction direct interaction crsas_6-6 4 10 unspecified role unspecified role unspecified role unspecified role Region 1-159 Region 1-159 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain A9CQL4:p.Phe145Met F145M mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain F M This feature has been corrected as a result of our quality control procedures. The original label was 'F145M'. Wed May 02 16:42:59 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe145met' Tue Jun 30 20:24:35 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Phe145Met' A9CQL4:p.Ile95Phe I95F/V mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain I F Wed May 02 19:21:36 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ile95phe' Tue Jun 30 19:41:58 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ile95Phe' A9CQL4:p.[Ile95Val;Phe102Trp] I95V/F102W mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain I V certain certain sequence position certain certain certain sequence position certain F W This feature has been corrected as a result of our quality control procedures. The original label was 'I95V/F102W'. Wed May 02 17:01:44 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ile95val,phe102trp' Tue Jun 30 16:18:34 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Ile95Val;Phe102Trp]' A9CQL4:p.[Phe102Trp;Phe145Tyr] F102W/F145Y mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain F Y certain certain sequence position certain certain certain sequence position certain F W This feature has been corrected as a result of our quality control procedures. The original label was 'F102W/F145Y'. Wed May 02 16:00:55 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe102trp,phe145tyr' Tue Jun 30 16:39:34 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Phe102Trp;Phe145Tyr]' A9CQL4:p.[Lys105Arg;Asp144Glu] K105R/D144E mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain D E certain certain sequence position certain certain certain sequence position certain K R This feature has been corrected as a result of our quality control procedures. The original label was 'K105R/D144E'. Wed May 02 16:37:49 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'lys105arg,asp144glu' Tue Jun 30 20:11:38 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Lys105Arg;Asp144Glu]' A9CQL4:p.His150Arg H150R mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain H R This feature has been corrected as a result of our quality control procedures. The original label was 'H150R'. Wed May 02 19:12:50 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'his150arg' Tue Jun 30 19:49:52 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.His150Arg' A9CQL4:p.Lys105Arg K105R mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain K R This feature has been corrected as a result of our quality control procedures. The original label was 'K105R'. Wed May 02 19:48:27 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'lys105arg' Tue Jun 30 19:49:54 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Lys105Arg' A9CQL4:p.[Ile95Cys;Lys146Cys] I95C/K146C mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain I C certain certain sequence position certain certain certain sequence position certain K C This feature has been corrected as a result of our quality control procedures. The original label was 'I95C/K146C'. Wed May 02 20:17:37 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ile95cys,lys146cys' Tue Jun 30 17:58:20 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Ile95Cys;Lys146Cys]' A9CQL4:p.Ile95Val mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength certain certain sequence position certain certain certain sequence position certain I V Wed May 02 16:46:12 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ile95val' Tue Jun 30 18:41:59 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ile95Val' ecolx Escherichia coli direct interaction direct interaction crsas_6-7 5 10 unspecified role unspecified role unspecified role unspecified role Region 1-503 Region 1-503 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction crsas_6-8 2 10 unspecified role unspecified role unspecified role unspecified role Region 1-159 Region 1-159 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain A9CQL4:p.[Gly104Cys;Phe145Cys] G104C/F145C mutation mutation certain certain sequence position certain certain certain sequence position certain F C certain certain sequence position certain certain certain sequence position certain G C This feature has been corrected as a result of our quality control procedures. The original label was 'G104C/F145C'. Wed May 02 17:51:53 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'gly104cys,phe145cys' Tue Jun 30 19:55:20 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Gly104Cys;Phe145Cys]' ecolx Escherichia coli direct interaction direct interaction crsas_6-9 6 10 unspecified role unspecified role unspecified role unspecified role Region 1-159 Region 1-159 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction