DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Structure and organization of heteromeric AMPA-type glutamate receptors. Structure and organization of heteromeric AMPA-type glutamate receptors. Science (New York, N.Y.) 2016 imex curation Herguedas B., García-Nafría J., Cais O., Fernández-Leiro R., Krieger J., Ho H., Greger IH. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip predetermined predetermined participant predetermined Herguedas B., García-Nafría J., Cais O., Fernández-Leiro R., Krieger J., Ho H., Greger IH. DIP original experiment: DIP-269123X Science (New York, N.Y.) 2016 IMEx Structure and organization of heteromeric AMPA-type glutamate receptors. Structure and organization of heteromeric AMPA-type glutamate receptors. Structure and organization of heteromeric AMPA-type glutamate receptors. Science (New York, N.Y.) 2016 imex curation Herguedas B., García-Nafría J., Cais O., Fernández-Leiro R., Krieger J., Ho H., Greger IH. Only protein-protein interactions human Homo sapiens Human x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Herguedas B., García-Nafría J., Cais O., Fernández-Leiro R., Krieger J., Ho H., Greger IH. DIP original experiment: DIP-269125X Science (New York, N.Y.) 2016 IMEx Structure and organization of heteromeric AMPA-type glutamate receptors. Structure and organization of heteromeric AMPA-type glutamate receptors. Structure and organization of heteromeric AMPA-type glutamate receptors. Science (New York, N.Y.) 2016 imex curation Herguedas B., García-Nafría J., Cais O., Fernández-Leiro R., Krieger J., Ho H., Greger IH. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip predetermined predetermined participant predetermined Herguedas B., García-Nafría J., Cais O., Fernández-Leiro R., Krieger J., Ho H., Greger IH. DIP original experiment: DIP-269122X Science (New York, N.Y.) 2016 IMEx Structure and organization of heteromeric AMPA-type glutamate receptors. Structure and organization of heteromeric AMPA-type glutamate receptors. Structure and organization of heteromeric AMPA-type glutamate receptors. Science (New York, N.Y.) 2016 imex curation Herguedas B., García-Nafría J., Cais O., Fernández-Leiro R., Krieger J., Ho H., Greger IH. Only protein-protein interactions human Homo sapiens Human x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Herguedas B., García-Nafría J., Cais O., Fernández-Leiro R., Krieger J., Ho H., Greger IH. DIP original experiment: DIP-269124X Science (New York, N.Y.) 2016 IMEx Structure and organization of heteromeric AMPA-type glutamate receptors. Structure and organization of heteromeric AMPA-type glutamate receptors. Structure and organization of heteromeric AMPA-type glutamate receptors. Science (New York, N.Y.) 2016 imex curation Herguedas B., García-Nafría J., Cais O., Fernández-Leiro R., Krieger J., Ho H., Greger IH. Only protein-protein interactions human Homo sapiens Human 3d-em 3D electron microscopy 3D-EM electron tomog predetermined predetermined participant predetermined Herguedas B., García-Nafría J., Cais O., Fernández-Leiro R., Krieger J., Ho H., Greger IH. DIP original experiment: DIP-269126X Science (New York, N.Y.) 2016 IMEx Structure and organization of heteromeric AMPA-type glutamate receptors. Structure and organization of heteromeric AMPA-type glutamate receptors. Structure and organization of heteromeric AMPA-type glutamate receptors. Science (New York, N.Y.) 2016 imex curation Herguedas B., García-Nafría J., Cais O., Fernández-Leiro R., Krieger J., Ho H., Greger IH. Only protein-protein interactions human Homo sapiens Human tem transmission electron microscopy tem predetermined predetermined participant predetermined Herguedas B., García-Nafría J., Cais O., Fernández-Leiro R., Krieger J., Ho H., Greger IH. DIP original experiment: DIP-269127X Science (New York, N.Y.) 2016 IMEx Structure and organization of heteromeric AMPA-type glutamate receptors. p19491-2 Glutamate receptor 2 Gria2 Glur2 AMPA-selective glutamate receptor 2 GluR-B GluR-K2 Glutamate receptor ionotropic, AMPA 2 protein protein rat Rattus norvegicus (Rat) Rat MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKVAKNPQNINPSSSQNSQNFATYKEGYNVYGIESVKI DIP protein P19491-2 original sequence version: 144 DIP protein P19491-2 original sequence version: 177 DIP protein P19491-2 original sequence version: 170 DIP protein P19491-2 original sequence version: 186 p19493-2 Glutamate receptor 4 Gria4 Glur4 AMPA-selective glutamate receptor 4 GluR-D Glutamate receptor ionotropic, AMPA 4 Flip protein protein rat Rattus norvegicus (Rat) Rat MRIICRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVTKLMDRWKKLDQREYPGSETPPKYTSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNVQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDMPTLGNDTAAIENRTVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKGKFAFLLESTMNEYTEQRKPCDTMKVGGNLDSKGYGVATPKGSSLRTPVNLAVLKLSEAGVLDKLKNKWWYDKGECGPKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKLTFSEATRNKARLSITGSVGENGRVLTPDCPKAVHTGTAIRQSSGLAVIASDLP DIP protein P19493-2 original sequence version: 117 DIP protein P19493-2 original sequence version: 155 p19492-2 Glutamate receptor 3 Gria3 Glur3 AMPA-selective glutamate receptor 3 GluR-C GluR-K3 Glutamate receptor ionotropic, AMPA 3 protein protein rat Rattus norvegicus (Rat) Rat MGQSVLRAVFFLVLGLLGHSHGGFPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFPTDADVQFVIQMRPALKGAILSLLSYYKWEKFVYLYDTERGFSVLQAIMEAAVQNNWQVTARSVGNIKDVQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANLGFTDILLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAPLKYTSALTHDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNIQFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFVPFSDQQISNDSSSSENRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALGTPVNLAVLKLSEQGILDKLKNKWWYDKGECGAKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSRAESKRMKLTKNTQNFKPAPATNTQNYATYREGYNVYGTESVKI DIP protein P19492-2 original sequence version: 158 gria2-gria4-1 4 8 unspecified role unspecified role unspecified role unspecified role Region 21-400 Region 21-400 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human 7 unspecified role unspecified role unspecified role unspecified role Region 22-400 Region 22-400 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human direct interaction direct interaction gria3-gria2-1 3 9 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human Homo sapiens Human 7 unspecified role unspecified role prey prey Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human Homo sapiens Human physical association physical association gria2-gria3-2 5 9 unspecified role unspecified role unspecified role unspecified role Region 23-888 Region 23-888 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human 7 unspecified role unspecified role unspecified role unspecified role Region 22-883 Region 22-883 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human direct interaction direct interaction gria2-gria3-3 2 9 unspecified role unspecified role unspecified role unspecified role Region 23-402 Region 23-402 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human 7 unspecified role unspecified role unspecified role unspecified role Region 22-400 Region 22-400 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human direct interaction direct interaction gria4-gria2-1 1 8 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human Homo sapiens Human 7 unspecified role unspecified role prey prey Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human Homo sapiens Human physical association physical association gria2-gria3-4 6 9 unspecified role unspecified role unspecified role unspecified role Region 23-888 Region 23-888 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human 7 unspecified role unspecified role unspecified role unspecified role Region 22-883 Region 22-883 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human direct interaction direct interaction