DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages. Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages. Science (New York, N.Y.) 2015 imex curation Schumacher MA., Tonthat NK., Lee J., Rodriguez-Castañeda FA., Chinnam NB., Kalliomaa-Sanford AK., Ng IW., Barge MT., Shaw PL., Barillà D. Only protein-protein interactions ecolx Escherichia coli solution sedimentati cosedimentation in solution solution sedimentati predetermined predetermined participant predetermined Schumacher MA., Tonthat NK., Lee J., Rodriguez-Castañeda FA., Chinnam NB., Kalliomaa-Sanford AK., Ng IW., Barge MT., Shaw PL., Barillà D. DIP original experiment: DIP-266307X Science (New York, N.Y.) 2015 IMEx Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages. Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages. Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages. Science (New York, N.Y.) 2015 imex curation Schumacher MA., Tonthat NK., Lee J., Rodriguez-Castañeda FA., Chinnam NB., Kalliomaa-Sanford AK., Ng IW., Barge MT., Shaw PL., Barillà D. Only protein-protein interactions in vitro In vitro spr surface plasmon resonance Optical biosensor BIAcore(r) BIAcore(r) Optical biosensor spr predetermined predetermined participant predetermined Schumacher MA., Tonthat NK., Lee J., Rodriguez-Castañeda FA., Chinnam NB., Kalliomaa-Sanford AK., Ng IW., Barge MT., Shaw PL., Barillà D. DIP original experiment: DIP-266305X Science (New York, N.Y.) 2015 IMEx Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages. Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages. Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages. Science (New York, N.Y.) 2015 imex curation Schumacher MA., Tonthat NK., Lee J., Rodriguez-Castañeda FA., Chinnam NB., Kalliomaa-Sanford AK., Ng IW., Barge MT., Shaw PL., Barillà D. Only protein-protein interactions in vitro In vitro mst microscale thermophoresis mst predetermined predetermined participant predetermined Schumacher MA., Tonthat NK., Lee J., Rodriguez-Castañeda FA., Chinnam NB., Kalliomaa-Sanford AK., Ng IW., Barge MT., Shaw PL., Barillà D. DIP original experiment: DIP-266310X Science (New York, N.Y.) 2015 IMEx Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages. Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages. Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages. Science (New York, N.Y.) 2015 imex curation Schumacher MA., Tonthat NK., Lee J., Rodriguez-Castañeda FA., Chinnam NB., Kalliomaa-Sanford AK., Ng IW., Barge MT., Shaw PL., Barillà D. Only protein-protein interactions ecolx Escherichia coli molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Schumacher MA., Tonthat NK., Lee J., Rodriguez-Castañeda FA., Chinnam NB., Kalliomaa-Sanford AK., Ng IW., Barge MT., Shaw PL., Barillà D. DIP original experiment: DIP-266311X Science (New York, N.Y.) 2015 IMEx Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages. Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages. Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages. Science (New York, N.Y.) 2015 imex curation Schumacher MA., Tonthat NK., Lee J., Rodriguez-Castañeda FA., Chinnam NB., Kalliomaa-Sanford AK., Ng IW., Barge MT., Shaw PL., Barillà D. Only protein-protein interactions ecolx Escherichia coli light scattering light scattering predetermined predetermined participant predetermined Schumacher MA., Tonthat NK., Lee J., Rodriguez-Castañeda FA., Chinnam NB., Kalliomaa-Sanford AK., Ng IW., Barge MT., Shaw PL., Barillà D. DIP original experiment: DIP-266309X Science (New York, N.Y.) 2015 IMEx Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages. Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages. Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages. Science (New York, N.Y.) 2015 imex curation Schumacher MA., Tonthat NK., Lee J., Rodriguez-Castañeda FA., Chinnam NB., Kalliomaa-Sanford AK., Ng IW., Barge MT., Shaw PL., Barillà D. Only protein-protein interactions ecolx Escherichia coli x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Schumacher MA., Tonthat NK., Lee J., Rodriguez-Castañeda FA., Chinnam NB., Kalliomaa-Sanford AK., Ng IW., Barge MT., Shaw PL., Barillà D. DIP original experiment: DIP-266315X Science (New York, N.Y.) 2015 IMEx Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages. Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages. Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages. Science (New York, N.Y.) 2015 imex curation Schumacher MA., Tonthat NK., Lee J., Rodriguez-Castañeda FA., Chinnam NB., Kalliomaa-Sanford AK., Ng IW., Barge MT., Shaw PL., Barillà D. Only protein-protein interactions ecolx Escherichia coli x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Schumacher MA., Tonthat NK., Lee J., Rodriguez-Castañeda FA., Chinnam NB., Kalliomaa-Sanford AK., Ng IW., Barge MT., Shaw PL., Barillà D. DIP original experiment: DIP-266314X Science (New York, N.Y.) 2015 IMEx Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages. Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages. Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages. Science (New York, N.Y.) 2015 imex curation Schumacher MA., Tonthat NK., Lee J., Rodriguez-Castañeda FA., Chinnam NB., Kalliomaa-Sanford AK., Ng IW., Barge MT., Shaw PL., Barillà D. Only protein-protein interactions ecolx Escherichia coli molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Schumacher MA., Tonthat NK., Lee J., Rodriguez-Castañeda FA., Chinnam NB., Kalliomaa-Sanford AK., Ng IW., Barge MT., Shaw PL., Barillà D. DIP original experiment: DIP-266308X Science (New York, N.Y.) 2015 IMEx Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages. Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages. Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages. Science (New York, N.Y.) 2015 imex curation Schumacher MA., Tonthat NK., Lee J., Rodriguez-Castañeda FA., Chinnam NB., Kalliomaa-Sanford AK., Ng IW., Barge MT., Shaw PL., Barillà D. Only protein-protein interactions in vitro In vitro spr surface plasmon resonance Optical biosensor BIAcore(r) BIAcore(r) Optical biosensor spr predetermined predetermined participant predetermined Schumacher MA., Tonthat NK., Lee J., Rodriguez-Castañeda FA., Chinnam NB., Kalliomaa-Sanford AK., Ng IW., Barge MT., Shaw PL., Barillà D. DIP original experiment: DIP-266306X Science (New York, N.Y.) 2015 IMEx Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages. Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages. Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages. Science (New York, N.Y.) 2015 imex curation Schumacher MA., Tonthat NK., Lee J., Rodriguez-Castañeda FA., Chinnam NB., Kalliomaa-Sanford AK., Ng IW., Barge MT., Shaw PL., Barillà D. Only protein-protein interactions in vitro In vitro saxs x ray scattering saxs predetermined predetermined participant predetermined Schumacher MA., Tonthat NK., Lee J., Rodriguez-Castañeda FA., Chinnam NB., Kalliomaa-Sanford AK., Ng IW., Barge MT., Shaw PL., Barillà D. DIP original experiment: DIP-266312X Science (New York, N.Y.) 2015 IMEx Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages. Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages. Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages. Science (New York, N.Y.) 2015 imex curation Schumacher MA., Tonthat NK., Lee J., Rodriguez-Castañeda FA., Chinnam NB., Kalliomaa-Sanford AK., Ng IW., Barge MT., Shaw PL., Barillà D. Only protein-protein interactions ecolx Escherichia coli x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Schumacher MA., Tonthat NK., Lee J., Rodriguez-Castañeda FA., Chinnam NB., Kalliomaa-Sanford AK., Ng IW., Barge MT., Shaw PL., Barillà D. DIP original experiment: DIP-266313X Science (New York, N.Y.) 2015 IMEx Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages. o93707_9cren ParB domain-containing protein protein protein sulfolobus sp. nob8h2 Sulfolobus sp. NOB8H2 MSKLKEYKEISIEEIKEVEEFKNFVPENNMYDKIKEDIAKNGIKVPLIVNQNYELINGYTRLKIARELGIKEVPVAIYETEGRADEYDLLVSTNLTQRQLNRAQALALIEKAVEEKMKMSKKNQNNDNNTKVLKVESGETQLSATESKKIEKSESKERKVESPGDSTFSNNEKKIENITEIKNAIKEELKKHNIKIDDNTLNKYIRIKQNSHWLTDYILKGKIGITTAYELYTKLQEMGLLEAVAKLPPYERNALLTDGRKIILNGRKDLLEEIVNHRMAVSQAISKLKTDEKLEKLQRSKKKPRAKEENLEDEEEEEIESEGEQREDNVSDNDEEYDFVGEWQKAQEEEEKEKQLTRLDDEAPPTKLEIYTPKADLESLYRAMPSIKKLVDEGKLTEKDAEKVYEIWRNMEAIYKQASLLWYNTVDLLLKRIGLSEKEREEIFYEMVRPYFRLFSREEVFPKEVLEGKL DIP protein O93707 original sequence version: 40 o93706_9cren HTH arsR-type domain-containing protein protein protein sulfolobus sp. nob8h2 Sulfolobus sp. NOB8H2 MGKISTDKYIFLTPRAYIIVHLLKVGKAKASEISENTQIPYQTVIQNIRWLLAEGYVVKEQKGEEIYYKLTDKGKQLATAELEKIRKLVEVVQ DIP protein O93706 original sequence version: 73 o93708_9cren AAA_31 domain-containing protein protein protein sulfolobus sp. nob8h2 Sulfolobus sp. NOB8H2 MIAKVITIHNFKGGVGKTTTTAIIAMGLGAMGKRVLLIDFDAQMSLTQIFVREEDRLKILESSHDVTQDKSAFALLRTMEPARIKFFHEGKGVKFGIDVIPGSYMSIFKLMFEGYIPIQSEWNILRMLDLYRDQYDYILIDTAPSDTVTIKPILRASHYLLIPEDGTPEAFTAMRIFLNEALPKYILPRPEGGFYKYPRILGVILTRVRRNSTAILMKHNKILEEELSNSELKDHVIYPPYFGADKDNPEDYILSSRKEYLSDLIWRDEKRAPISEVFDKLFLVDDKVQKDLYAFFSKVFTEIPKEVVRRVENDQ DIP protein O93708 original sequence version: 44 o93706_9cren-1 8 13 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction o93707_9cren-o93706_9cren-1 2 13 unspecified role unspecified role prey prey ecolx Escherichia coli 12 unspecified role unspecified role bait bait ecolx Escherichia coli direct interaction direct interaction o93706_9cren-2 5 13 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction o93706_9cren-o93707_9cren-1 10 13 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli 12 unspecified role unspecified role unspecified role unspecified role Region 1-320 Region 1-320 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction o93707_9cren-o93708_9cren-1 9 14 unspecified role unspecified role prey prey ecolx Escherichia coli 12 unspecified role unspecified role bait bait ecolx Escherichia coli direct interaction direct interaction o93708_9cren-1 6 14 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction o93706_9cren-o93707_9cren-2 3 13 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli 12 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction o93706_9cren-3 11 13 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction o93706_9cren-4 1 13 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction o93707_9cren-1 7 12 unspecified role unspecified role unspecified role unspecified role Region 370-470 Region 370-470 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction o93707_9cren-2 4 12 unspecified role unspecified role unspecified role unspecified role Region 370-470 Region 370-470 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction