DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structure (London, England : 1993) 2015 imex curation DeBerg HA., Bankston JR., Rosenbaum JC., Brzovic PS., Zagotta WN., Stoll S. Only protein-protein interactions in vitro In vitro epr electron paramagnetic resonance ESR EPR EPR ESR epr predetermined predetermined participant predetermined DeBerg HA., Bankston JR., Rosenbaum JC., Brzovic PS., Zagotta WN., Stoll S. DIP original experiment: DIP-264888X Structure (London, England : 1993) 2015 IMEx Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structure (London, England : 1993) 2015 imex curation DeBerg HA., Bankston JR., Rosenbaum JC., Brzovic PS., Zagotta WN., Stoll S. Only protein-protein interactions in vitro In vitro epr electron paramagnetic resonance ESR EPR EPR ESR epr predetermined predetermined participant predetermined DeBerg HA., Bankston JR., Rosenbaum JC., Brzovic PS., Zagotta WN., Stoll S. DIP original experiment: DIP-264895X Structure (London, England : 1993) 2015 IMEx Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structure (London, England : 1993) 2015 imex curation DeBerg HA., Bankston JR., Rosenbaum JC., Brzovic PS., Zagotta WN., Stoll S. Only protein-protein interactions in vitro In vitro epr electron paramagnetic resonance ESR EPR EPR ESR epr predetermined predetermined participant predetermined DeBerg HA., Bankston JR., Rosenbaum JC., Brzovic PS., Zagotta WN., Stoll S. DIP original experiment: DIP-264889X Structure (London, England : 1993) 2015 IMEx Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structure (London, England : 1993) 2015 imex curation DeBerg HA., Bankston JR., Rosenbaum JC., Brzovic PS., Zagotta WN., Stoll S. Only protein-protein interactions in vitro In vitro epr electron paramagnetic resonance ESR EPR EPR ESR epr predetermined predetermined participant predetermined DeBerg HA., Bankston JR., Rosenbaum JC., Brzovic PS., Zagotta WN., Stoll S. DIP original experiment: DIP-264885X Structure (London, England : 1993) 2015 IMEx Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structure (London, England : 1993) 2015 imex curation DeBerg HA., Bankston JR., Rosenbaum JC., Brzovic PS., Zagotta WN., Stoll S. Only protein-protein interactions in vitro In vitro epr electron paramagnetic resonance ESR EPR EPR ESR epr predetermined predetermined participant predetermined DeBerg HA., Bankston JR., Rosenbaum JC., Brzovic PS., Zagotta WN., Stoll S. DIP original experiment: DIP-264886X Structure (London, England : 1993) 2015 IMEx Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structure (London, England : 1993) 2015 imex curation DeBerg HA., Bankston JR., Rosenbaum JC., Brzovic PS., Zagotta WN., Stoll S. Only protein-protein interactions in vitro In vitro epr electron paramagnetic resonance ESR EPR EPR ESR epr predetermined predetermined participant predetermined DeBerg HA., Bankston JR., Rosenbaum JC., Brzovic PS., Zagotta WN., Stoll S. DIP original experiment: DIP-264881X Structure (London, England : 1993) 2015 IMEx Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structure (London, England : 1993) 2015 imex curation DeBerg HA., Bankston JR., Rosenbaum JC., Brzovic PS., Zagotta WN., Stoll S. Only protein-protein interactions in vitro In vitro molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined DeBerg HA., Bankston JR., Rosenbaum JC., Brzovic PS., Zagotta WN., Stoll S. DIP original experiment: DIP-264877X Structure (London, England : 1993) 2015 IMEx Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structure (London, England : 1993) 2015 imex curation DeBerg HA., Bankston JR., Rosenbaum JC., Brzovic PS., Zagotta WN., Stoll S. Only protein-protein interactions in vitro In vitro epr electron paramagnetic resonance ESR EPR EPR ESR epr predetermined predetermined participant predetermined DeBerg HA., Bankston JR., Rosenbaum JC., Brzovic PS., Zagotta WN., Stoll S. DIP original experiment: DIP-264891X Structure (London, England : 1993) 2015 IMEx Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structure (London, England : 1993) 2015 imex curation DeBerg HA., Bankston JR., Rosenbaum JC., Brzovic PS., Zagotta WN., Stoll S. Only protein-protein interactions in vitro In vitro epr electron paramagnetic resonance ESR EPR EPR ESR epr predetermined predetermined participant predetermined DeBerg HA., Bankston JR., Rosenbaum JC., Brzovic PS., Zagotta WN., Stoll S. DIP original experiment: DIP-264882X Structure (London, England : 1993) 2015 IMEx Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structure (London, England : 1993) 2015 imex curation DeBerg HA., Bankston JR., Rosenbaum JC., Brzovic PS., Zagotta WN., Stoll S. Only protein-protein interactions in vitro In vitro nmr nuclear magnetic resonance NMR NMR nmr predetermined predetermined participant predetermined DeBerg HA., Bankston JR., Rosenbaum JC., Brzovic PS., Zagotta WN., Stoll S. DIP original experiment: DIP-264878X Structure (London, England : 1993) 2015 IMEx Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structure (London, England : 1993) 2015 imex curation DeBerg HA., Bankston JR., Rosenbaum JC., Brzovic PS., Zagotta WN., Stoll S. Only protein-protein interactions in vitro In vitro epr electron paramagnetic resonance ESR EPR EPR ESR epr predetermined predetermined participant predetermined DeBerg HA., Bankston JR., Rosenbaum JC., Brzovic PS., Zagotta WN., Stoll S. DIP original experiment: DIP-264884X Structure (London, England : 1993) 2015 IMEx Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structure (London, England : 1993) 2015 imex curation DeBerg HA., Bankston JR., Rosenbaum JC., Brzovic PS., Zagotta WN., Stoll S. Only protein-protein interactions in vitro In vitro epr electron paramagnetic resonance ESR EPR EPR ESR epr predetermined predetermined participant predetermined DeBerg HA., Bankston JR., Rosenbaum JC., Brzovic PS., Zagotta WN., Stoll S. DIP original experiment: DIP-264880X Structure (London, England : 1993) 2015 IMEx Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structure (London, England : 1993) 2015 imex curation DeBerg HA., Bankston JR., Rosenbaum JC., Brzovic PS., Zagotta WN., Stoll S. Only protein-protein interactions in vitro In vitro epr electron paramagnetic resonance ESR EPR EPR ESR epr predetermined predetermined participant predetermined DeBerg HA., Bankston JR., Rosenbaum JC., Brzovic PS., Zagotta WN., Stoll S. DIP original experiment: DIP-264892X Structure (London, England : 1993) 2015 IMEx Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structure (London, England : 1993) 2015 imex curation DeBerg HA., Bankston JR., Rosenbaum JC., Brzovic PS., Zagotta WN., Stoll S. Only protein-protein interactions in vitro In vitro epr electron paramagnetic resonance ESR EPR EPR ESR epr predetermined predetermined participant predetermined DeBerg HA., Bankston JR., Rosenbaum JC., Brzovic PS., Zagotta WN., Stoll S. DIP original experiment: DIP-264893X Structure (London, England : 1993) 2015 IMEx Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structure (London, England : 1993) 2015 imex curation DeBerg HA., Bankston JR., Rosenbaum JC., Brzovic PS., Zagotta WN., Stoll S. Only protein-protein interactions in vitro In vitro epr electron paramagnetic resonance ESR EPR EPR ESR epr predetermined predetermined participant predetermined DeBerg HA., Bankston JR., Rosenbaum JC., Brzovic PS., Zagotta WN., Stoll S. DIP original experiment: DIP-264887X Structure (London, England : 1993) 2015 IMEx Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structure (London, England : 1993) 2015 imex curation DeBerg HA., Bankston JR., Rosenbaum JC., Brzovic PS., Zagotta WN., Stoll S. Only protein-protein interactions in vitro In vitro epr electron paramagnetic resonance ESR EPR EPR ESR epr predetermined predetermined participant predetermined DeBerg HA., Bankston JR., Rosenbaum JC., Brzovic PS., Zagotta WN., Stoll S. DIP original experiment: DIP-264883X Structure (London, England : 1993) 2015 IMEx Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structure (London, England : 1993) 2015 imex curation DeBerg HA., Bankston JR., Rosenbaum JC., Brzovic PS., Zagotta WN., Stoll S. Only protein-protein interactions in vitro In vitro epr electron paramagnetic resonance ESR EPR EPR ESR epr predetermined predetermined participant predetermined DeBerg HA., Bankston JR., Rosenbaum JC., Brzovic PS., Zagotta WN., Stoll S. DIP original experiment: DIP-264894X Structure (London, England : 1993) 2015 IMEx Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structure (London, England : 1993) 2015 imex curation DeBerg HA., Bankston JR., Rosenbaum JC., Brzovic PS., Zagotta WN., Stoll S. Only protein-protein interactions in vitro In vitro epr electron paramagnetic resonance ESR EPR EPR ESR epr predetermined predetermined participant predetermined DeBerg HA., Bankston JR., Rosenbaum JC., Brzovic PS., Zagotta WN., Stoll S. DIP original experiment: DIP-264890X Structure (London, England : 1993) 2015 IMEx Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structure (London, England : 1993) 2015 imex curation DeBerg HA., Bankston JR., Rosenbaum JC., Brzovic PS., Zagotta WN., Stoll S. Only protein-protein interactions in vitro In vitro epr electron paramagnetic resonance ESR EPR EPR ESR epr predetermined predetermined participant predetermined DeBerg HA., Bankston JR., Rosenbaum JC., Brzovic PS., Zagotta WN., Stoll S. DIP original experiment: DIP-264879X Structure (London, England : 1993) 2015 IMEx Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. hcn2_mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 Brain cyclic nucleotide-gated channel 2 Hyperpolarization-activated cation channel 1 Bcng2 Hac1 Hcn2 protein protein mouse Mus musculus Mouse MDARGGGGRPGDSPGTTPAPGPPPPPPPPAPPQPQPPPAPPPNPTTPSHPESADEPGPRARLCSRDSACTPGAAKGGANGECGRGEPQCSPEGPARGPKVSFSCRGAASGPSAAEEAGSEEAGPAGEPRGSQASFLQRQFGALLQPGVNKFSLRMFGSQKAVEREQERVKSAGAWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTAPWIVFNVVSDTFFLMDLVLNFRTGIVIEDNTEIILDPEKIKKKYLRTWFVVDFVSSIPVDYIFLIVEKGIDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRICNLISMMLLLCHWDGCLQFLVPMLQDFPSDCWVSINNMVNHSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEDSILGELNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKEMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLHKVQHDLSSGVFNNQENAIIQEIVKYDREMVQQAELGQRVGLFPPPPPPQVTSAIATLQQAVAMSFCPQVARPLVGPLALGSPRLVRRAPPGPLPPAASPGPPAASPPAAPSSPRAPRTSPYGVPGSPATRVGPALPARRLSRASRPLSASQPSLPHGVPAPSPAASARPASSSTPRLGPAPTARTAAPSPDRRDSASPGAASGLDPLDSARSRLSSNL DIP protein O88703 original sequence version: 68 DIP protein O88703 original sequence version: 137 17CDC4DFF07AC039 q8iyb4-6 PEX5-related protein PEX5L PEX5R PXR2 PEX2-related protein PEX5-like protein Peroxin-5-related protein Peroxisome biogenesis factor 5-like Tetratricopeptide repeat-containing Rab8b-interacting protein protein protein human Homo sapiens Human MYQGHMQGKGSRAADKAVAMVMKEIPREESAEEKPLLTMTSQLVNEQQESRPLLSPSIDDFLCETKSEAIARPVTSNTAVLTTGLDLLDLSEPVSQTQTKAKKSEPSSKTSSLKKKADGSDLISTDAEQRGQPLRVPETSSLDLDIQTQLEKWDDVKFHGDRNTKGHPMAERKSSSSRTGSKELLWSSEHRSQPELSGGKSALNSESASELELVAPTQARLTKEHRWGSALLSRNHSLEEEFERAKAAVESDTEFWDKMQAEWEEMARRNWISENQEAQNQVTISASEKGYYFHTENPFKDWPGAFEEGLKRLKEGDLPVTILFMEAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTGHQQDACDALKNWIKQNPKYKYLVKSKKGSPGLTRRMSKSPVDSSVLEGVKELYLEAAHQNGDMIDPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRKSRNQQQVPHPAISGNIWAALRIALSLMDQPELFQAANLGDLDVLLRAFNLDP DIP protein Q8IYB4-6 original sequence version: 115 hcn4_human Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 HCN4 protein protein human Homo sapiens Human MDKLPPSMRKRLYSLPQQVGAKAWIMDEEEDAEEEGAGGRQDPSRRSIRLRPLPSPSPSAAAGGTESRSSALGAADSEGPARGAGKSSTNGDCRRFRGSLASLGSRGGGSGGTGSGSSHGHLHDSAEERRLIAEGDASPGEDRTPPGLAAEPERPGASAQPAASPPPPQQPPQPASASCEQPSVDTAIKVEGGAAAGDQILPEAEVRLGQAGFMQRQFGAMLQPGVNKFSLRMFGSQKAVEREQERVKSAGFWIIHPYSDFRFYWDLTMLLLMVGNLIIIPVGITFFKDENTTPWIVFNVVSDTFFLIDLVLNFRTGIVVEDNTEIILDPQRIKMKYLKSWFMVDFISSIPVDYIFLIVETRIDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPDDCWVSINNMVNNSWGKQYSYALFKAMSHMLCIGYGRQAPVGMSDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPPDTRQRIHDYYEHRYQGKMFDEESILGELSEPLREEIINFNCRKLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKETKLADGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVALDRLDRIGKKNSILLHKVQHDLNSGVFNYQENEIIQQIVQHDREMAHCAHRVQAAASATPTPTPVIWTPLIQAPLQAAAATTSVAIALTHHPRLPAAIFRPPPGSGLGNLGAGQTPRHLKRLQSLIPSALGSASPASSPSQVDTPSSSSFHIQQLAGFSAPAGLSPLLPSSSSSPPPGACGSPSAPTPSAGVAATTIAGFGHFHKALGGSLSSSDSPLLTPLQPGARSPQAAQPSPAPPGARGGLGLPEHFLPPPPSSRSPSSSPGQLGQPPGELSLGLATGPLSTPETPPRQPEPPSLVAGASGGASPVGFTPRGGLSPPGHSPGPPRTFPSAPPRASGSHGSLLLPPASSPPPPQVPQRRGTPPLTPGRLTQDLKLISASQPALPQDGAQTLRRASPHSSGESMAAFPLFPRAGGGSGGSGSSGGLGPPGRPYGAIPGQHVTLPRKTSSGSLPPPLSLFGARATSSGGPPLTAGPQREPGARPEPVRSKLPSNL DIP protein Q9Y3Q4 original sequence version: 122 DIP protein Q9Y3Q4 original sequence version: 131 7EFDD2D69CF1F9D9 hcn2-pex5l-1 1 20 unspecified role unspecified role unspecified role unspecified role Region 488-640 Region 488-640 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain R1-label R1-label r1 spin label r1 spin label certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 21 unspecified role unspecified role unspecified role unspecified role Region 223-303 Region 223-303 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain R1-label R1-label r1 spin label r1 spin label certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction hcn2-pex5l-2 6 20 unspecified role unspecified role unspecified role unspecified role Region 488-640 Region 488-640 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain R1-label R1-label r1 spin label r1 spin label certain certain sequence position certain certain certain sequence position certain certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 21 unspecified role unspecified role unspecified role unspecified role Region 223-303 Region 223-303 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction hcn2-pex5l-3 7 20 unspecified role unspecified role unspecified role unspecified role Region 488-640 Region 488-640 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 21 unspecified role unspecified role unspecified role unspecified role Region 223-303 Region 223-303 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction hcn2-pex5l-4 2 20 unspecified role unspecified role unspecified role unspecified role Region 488-640 Region 488-640 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain R1-label R1-label r1 spin label r1 spin label certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 21 unspecified role unspecified role unspecified role unspecified role Region 223-303 Region 223-303 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain R1-label R1-label r1 spin label r1 spin label certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction hcn2-pex5l-5 13 20 unspecified role unspecified role unspecified role unspecified role Region 488-640 Region 488-640 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain R1-label R1-label r1 spin label r1 spin label certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 21 unspecified role unspecified role unspecified role unspecified role Region 223-303 Region 223-303 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain R1-label R1-label r1 spin label r1 spin label certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction hcn2-pex5l-6 17 20 unspecified role unspecified role unspecified role unspecified role Region 488-640 Region 488-640 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain R1-label R1-label r1 spin label r1 spin label certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 21 unspecified role unspecified role unspecified role unspecified role Region 223-303 Region 223-303 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain R1-label R1-label r1 spin label r1 spin label certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction hcn4-pex5l-1 10 22 unspecified role unspecified role unspecified role unspecified role Region 563-727 Region 563-727 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 21 unspecified role unspecified role unspecified role unspecified role Region 223-303 Region 223-303 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction hcn2-pex5l-7 8 20 unspecified role unspecified role unspecified role unspecified role Region 488-640 Region 488-640 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain R1-label R1-label r1 spin label r1 spin label certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 21 unspecified role unspecified role unspecified role unspecified role R1-label R1-label r1 spin label r1 spin label certain certain sequence position certain certain certain sequence position certain Region 223-303 Region 223-303 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction hcn2-pex5l-8 4 20 unspecified role unspecified role unspecified role unspecified role Region 488-640 Region 488-640 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain R1-label R1-label r1 spin label r1 spin label certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 21 unspecified role unspecified role unspecified role unspecified role Region 223-303 Region 223-303 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain R1-label R1-label r1 spin label r1 spin label certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction hcn2-pex5l-9 9 20 unspecified role unspecified role unspecified role unspecified role Region 488-640 Region 488-640 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain R1-label R1-label r1 spin label r1 spin label certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 21 unspecified role unspecified role unspecified role unspecified role Region 223-303 Region 223-303 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction hcn2-pex5l-10 19 20 unspecified role unspecified role unspecified role unspecified role Region 488-640 Region 488-640 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain R1-label R1-label r1 spin label r1 spin label certain certain sequence position certain certain certain sequence position certain certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 21 unspecified role unspecified role unspecified role unspecified role Region 223-303 Region 223-303 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction hcn2-pex5l-11 14 20 unspecified role unspecified role unspecified role unspecified role Region 488-640 Region 488-640 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain R1-label R1-label r1 spin label r1 spin label certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 21 unspecified role unspecified role unspecified role unspecified role Region 223-303 Region 223-303 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain R1-label R1-label r1 spin label r1 spin label certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction hcn2-pex5l-12 16 20 unspecified role unspecified role unspecified role unspecified role Region 488-640 Region 488-640 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain R1-label R1-label r1 spin label r1 spin label certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 21 unspecified role unspecified role unspecified role unspecified role Region 223-303 Region 223-303 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain R1-label R1-label r1 spin label r1 spin label certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction hcn2-pex5l-13 5 20 unspecified role unspecified role unspecified role unspecified role Region 488-640 Region 488-640 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain R1-label R1-label r1 spin label r1 spin label certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 21 unspecified role unspecified role unspecified role unspecified role Region 223-303 Region 223-303 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain R1-label R1-label r1 spin label r1 spin label certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction hcn2-pex5l-14 3 20 unspecified role unspecified role unspecified role unspecified role Region 488-640 Region 488-640 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain R1-label R1-label r1 spin label r1 spin label certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 21 unspecified role unspecified role unspecified role unspecified role Region 223-303 Region 223-303 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain R1-label R1-label r1 spin label r1 spin label certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction hcn2-pex5l-15 15 20 unspecified role unspecified role unspecified role unspecified role Region 488-640 Region 488-640 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain R1-label R1-label r1 spin label r1 spin label certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 21 unspecified role unspecified role unspecified role unspecified role Region 223-303 Region 223-303 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain R1-label R1-label r1 spin label r1 spin label certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction hcn2-pex5l-16 12 20 unspecified role unspecified role unspecified role unspecified role Region 488-640 Region 488-640 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain R1-label R1-label r1 spin label r1 spin label certain certain sequence position certain certain certain sequence position certain certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 21 unspecified role unspecified role unspecified role unspecified role Region 223-303 Region 223-303 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction hcn2-pex5l-17 11 20 unspecified role unspecified role unspecified role unspecified role Region 488-640 Region 488-640 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain R1-label R1-label r1 spin label r1 spin label certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 21 unspecified role unspecified role unspecified role unspecified role Region 223-303 Region 223-303 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain R1-label R1-label r1 spin label r1 spin label certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction hcn2-pex5l-18 18 20 unspecified role unspecified role unspecified role unspecified role Region 488-640 Region 488-640 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain R1-label R1-label r1 spin label r1 spin label certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 21 unspecified role unspecified role unspecified role unspecified role Region 223-303 Region 223-303 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain R1-label R1-label r1 spin label r1 spin label certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction