DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Structure of the vacuolar H+-ATPase rotary motor reveals new mechanistic insights. Structure of the vacuolar H+-ATPase rotary motor reveals new mechanistic insights. Structure (London, England : 1993) 2015 imex curation Rawson S., Phillips C., Huss M., Tiburcy F., Wieczorek H., Trinick J., Harrison MA., Muench SP. Only protein-protein interactions manse Manduca sexta (Tobacco hawkmoth) Tobacco hornworm Tobacco hawkmoth tem transmission electron microscopy tem predetermined predetermined participant predetermined Rawson S., Phillips C., Huss M., Tiburcy F., Wieczorek H., Trinick J., Harrison MA., Muench SP. DIP original experiment: DIP-264804X Structure (London, England : 1993) 2015 IMEx Structure of the vacuolar H+-ATPase rotary motor reveals new mechanistic insights. Structure of the vacuolar H+-ATPase rotary motor reveals new mechanistic insights. Structure of the vacuolar H+-ATPase rotary motor reveals new mechanistic insights. Structure (London, England : 1993) 2015 imex curation Rawson S., Phillips C., Huss M., Tiburcy F., Wieczorek H., Trinick J., Harrison MA., Muench SP. Only protein-protein interactions manse Manduca sexta (Tobacco hawkmoth) Tobacco hornworm Tobacco hawkmoth 3d-em 3D electron microscopy 3D-EM electron tomog predetermined predetermined participant predetermined Rawson S., Phillips C., Huss M., Tiburcy F., Wieczorek H., Trinick J., Harrison MA., Muench SP. DIP original experiment: DIP-264803X Structure (London, England : 1993) 2015 IMEx Structure of the vacuolar H+-ATPase rotary motor reveals new mechanistic insights. vatl_manse V-type proton ATPase 16 kDa proteolipid subunit VHA16 Vacuolar proton pump 16 kDa proteolipid subunit protein protein manse Manduca sexta (Tobacco hawkmoth) Tobacco hornworm Tobacco hawkmoth MAENPIYGPFFGVMGAASAIIFSALGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIAGSLDSPSNNYTLYRGFIHLGAGLAVGFSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVAIYLYTKQ DIP protein P31403 original sequence version: 89 vatc_manse V-type proton ATPase subunit C Vacuolar proton pump subunit C protein protein manse Manduca sexta (Tobacco hawkmoth) Tobacco hornworm Tobacco hawkmoth MSEYWLISAPGDKTCQQTWEALNQATKANNLSLNYKFPIPDLKVGTLDQLVGLSDDLGKLDTFVEGVTRKVAQYLGEVLEDQRDKLHENLTANNDDLPHYLTRFQWDMAKYPIKQSLRNIADIISKQVGQIDADLKVKSSAYNALKGNLQNLEKKQTGSLLTRNLADLVKKEHFILDSEYLTTLLVIVPKSMFNDWNANYEKITDMIVPRSTQLIHQDGDYGLFTVTLFKKVVDEFKLHARERKFVVREFAYNEADLVAGKNEITKLLTDKKKQFGPLVRWLKVNFSECFCAWIHVKALRVFVESVLRYGLPVNFQAALLVPSRRSARRLRDTLHALYAHLDHSAHHHANAQQDSVELAGLGFGQSEYYPYVFYKINIDMIEKAA DIP protein Q9U5N1 original sequence version: 54 vatd_manse V-type proton ATPase subunit D Vacuolar proton pump subunit D protein protein manse Manduca sexta (Tobacco hawkmoth) Tobacco hornworm Tobacco hawkmoth MSGKDRLAIFPSRGAQMLMKGRLAGAQKGHGLLKKKADALQVRFRLILSKIIETKTLMGEVMKEAAFSLAEAKFTTGDFNQVVLQNVTKAQIKIRSKKDNVAGVTLPIFESYQDGSDTYELAGLARGGQQLAKLKKNFQSAVKLLVELASLQTSFVTLDEVIKITNRRVNAIEHVIIPRLERTLAYIISELDELEREEFYRLKKIQDKKKIIKDKAEAKKAALRAAGQDLRDSANLLDEGDEDLLF DIP protein Q9U0S4 original sequence version: 56 vatb_manse V-type proton ATPase subunit B VHA55 Vacuolar proton pump subunit B protein protein manse Manduca sexta (Tobacco hawkmoth) Tobacco hornworm Tobacco hawkmoth MAKTLSAAQANKEHVLAVSRDFISQPRLTYKTVSGVNGPLVILDEVKFPKFSEIVQLKLADGTHRSGQVLEVSGSKAVVQVFEGTSGIDAKNTLCEFTGDILRTPVSEDMLGRVFNGSGKPIDKGPPILAEDFLDIQGQPINPWSRIYPEEMIQTGISAIDVMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKIPGKSVLDDHEDNFAIVFAAMGVNMETARFFKQDFEENGSMENVCLFLNLANDPTIERIITPRLALTAAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRQIYPPVNVLPSLSRLMKSAIGEGMTRKDHSDVSNQLYACYAIGKDVQAMKAVVGEEALTPDDLLYLEFLTKFEKNFITQGNYENRTVFESLDIGWQLLRIFPKEMLKRIPASILAEFYPRDSRH DIP protein P31401 original sequence version: 82 vatg_manse V-type proton ATPase subunit G V-ATPase 13 kDa subunit Vacuolar proton pump subunit G protein protein manse Manduca sexta (Tobacco hawkmoth) Tobacco hornworm Tobacco hawkmoth MASQTHGIQQLLAAEKRAAEKVSEARKRKAKRLKQAKEEAQDEVEKYRQERERQFKEFEAKHMGTREGVAAKIDAETRIKIDEMNKMVQTQKEAVIKDVLNLVYDIKPELHINYRVV DIP protein Q25532 original sequence version: 68 va0d_manse V-type proton ATPase subunit d M40 V-ATPase 40 kDa subunit Vacuolar proton pump subunit d protein protein manse Manduca sexta (Tobacco hawkmoth) Tobacco hornworm Tobacco hawkmoth MKGCIFNIDAGYLEGLCRGFKCGILKQSDYLNLVQCETLEDLKLHLQGTDYGTFLANEPSPLSVSTIDDKLREKLVIEFQHLRNHSVEPLSTFLDFITYSYMIDNIILLITGTLHQRPISELIPKCHPLGSFEQMEAIHVAATPAELYNAVLVDTPLAPFFVDCISEQDLDEMNIEIIRNTLYKAYLEAFYDFCKQIGGTTADVMCEILAFEADRRAIIITINSFGTELSKDDRAKLYPRCGKLNPDGLAALARADDYEQVKAVAEYYAEYSALFEGAGNNVGDKTLEDKFFEHEVNLNVHAFLQQFHFGVFYSYLKLKEQECRNIVWISECVAQKHRAKIDNYIPIF DIP protein Q25531 original sequence version: 68 o76959_manse V-type proton ATPase subunit protein protein manse Manduca sexta (Tobacco hawkmoth) Tobacco hornworm Tobacco hawkmoth MGASFVPITVFTILWGVVGIVCPIFAPKGPNRGIIQVVLMLTAATCWLFWLCAYMAQMNPLIGPRLNNETLIWISRTWGNPISNHTGA DIP protein O76959 original sequence version: 40 vatf_manse V-type proton ATPase subunit F VHA14 V-ATPase 14 kDa subunit Vacuolar proton pump subunit F protein protein manse Manduca sexta (Tobacco hawkmoth) Tobacco hornworm Tobacco hawkmoth MALHAAVKGKLISVIGDEDTCVGFLLGGIGEINKNRHPNFMVVDKNTPVSEIEECFKRFVKRDDIDIILINQNVAELVRHVIDAHTAPVPSVLEIPSKDHPYDASKDSILRRAKGMFNPEDLVR DIP protein P31478 original sequence version: 79 vath_manse V-type proton ATPase subunit H Vacuolar proton pump subunit H protein protein manse Manduca sexta (Tobacco hawkmoth) Tobacco hornworm Tobacco hawkmoth MANIGDEKVSQLIPTLGDDKIDMIAATSVLQIRASEIRQTQINWQSYLQGQMITQRDHDFIVNLDQRGQKDLPDKNPDACADVFLNLLTHISKDHTIQYILVLIDDILSEDKSRVKIFRETKYSGNIWQPFLNLLNRQDEFVQHMTARIIAKLACWHPQLMDKSDLHFYLSWLKDQLKMNNNDYIQSVARCLQMMLRVDEYRFAFLSVDGISTLLSILASRVNFQVQYQLVFCLWVLTFNPLLAEKMNKFNAIPILADILSDSVKEKVTRIVLAVFRNLIEKPQDQQVAKEHCIAMVQCKVLKQLSILEQKRSDDEDIMNDVEFLNERLQASVQDLSSFDQYATEVKSGRLEWSPVHKSAKFWRENAARLNERGQELLRTLVHLLEKSHDPVVLAVACYDVGEYVRHYPRGKHIIEQLGGKQRVMYLLSHDDPNVRYEALLAVQKLMVHNWEYLGKQLEKEQIDKQAGTVVGAKA DIP protein Q9U5N0 original sequence version: 70 q9u5m9_manse V-type proton ATPase subunit a mva protein protein manse Manduca sexta (Tobacco hawkmoth) Tobacco hornworm Tobacco hawkmoth MGSLFRSEEMTLCQLFLQSEAAYACVSELGELGLVQFRDLNPDVNAFQRKFVNEVRRCDEMERKLRYLEKEIRRDGIPMLEIPGECPEAPQPREMIDLEATFEKLENELREVNQNAEALKRNYLELTELKHILRKTQVFFDEMADPSREEEQVTLLGEEGLMAGGQALKLGFVAGVILRERIPAFERMLWRACRGNVFLRQAEIDTPLEDPSSSDQVYKSVFIIFFQGDQLKTRVKKICEGFRATLYPCPESPADRREMAMGVMTRIEDLNTVLGQTQDHRHRVLVAAAKNIKNWFVKVRKIKAIYHTLNLFNLDVTQKCLIAECWVPALDLETIQLALRRGTERSGSSVPPILNRMETLEDPPTYNRNNKFTQAFQNLIYAYGVATYREVNPAPYTIITFPFLFAVMFGDLGHGALMAAFGFWMCYKEKPLQAKKIDSEIWNIFFGGRYIILLMGLFSMYTGLIYNDIFSKSLNIFGSSWRQNYNASTLTENKLLQLNPDSPDYLQYPYPFGIDPVWQLAEANKIIFMNAYKMKISIIIGVFHMLFGVCLSLWNHLYFKRRISVYVEFIPQILFLTLLFFYMVLLMFIKWTSYGPTPGAFGSQDPAIVKTSAYCAPSILITFINMMLFKTDANTRPQCDDTMYAGQLQLQKFFVIVALLCVPVMLFGKPYFIMKEQKQRARQGHQPVEGAAENGTAGGAPVPSSGHHDDDITEVFIHQGIHTIEYVLGSVSHTASYLRLWALSLAHAQLAEVAWNMLLRKGLMSTDFQGGIFLYIVFAGWAAISVSILVLMEGLSAFLHTLRLHWVEFQSKFYAGEGLSLPTGSRFEVILDSAGPGRGVN DIP protein Q9U5M9 original sequence version: 45 vate_manse V-type proton ATPase subunit E VHA26 V-ATPase 26 kDa subunit Vacuolar proton pump subunit E protein protein manse Manduca sexta (Tobacco hawkmoth) Tobacco hornworm Tobacco hawkmoth MALSDADVQKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQQQRLKIMEYYEKKEKQVELQKKIQSSNMLNQARLKVLKVREDHVRNVLDEARKRLAEVPKDIKLYSDLLVTLIVQALFQLVEPTVTLRVRQADKALVESLLGRAQQDYKAKIKKDVVLKIDNENFLPPDTCGGIELIAAKGRIKISNTLESRLELIAQQLLPEIRNALFGRNPNRKFTD DIP protein P31402 original sequence version: 70 vata_manse V-type proton ATPase catalytic subunit A VHAA V-ATPase 69 kDa subunit Vacuolar proton pump subunit alpha protein protein manse Manduca sexta (Tobacco hawkmoth) Tobacco hornworm Tobacco hawkmoth MASKGGLKTIANEENEERFGYVFAVSGPVVTAEKMSGSAMYELVRVGYNELVGEIIRLEGDMATIQVYEETSGVTVGDPVLRTGKPLSVELGPGILGSIFDGIQRPLKDINELTQSIYIPKGVNVPSLAREVDWEFNPLNVKVGSHITGGDLYGIVHENTLVKHKMLMPPRAKGTVTYIAPAGNYKVTDVVLETEFDGEKAQYTMLQVWPVRQPRPVTEKLPANHPLLTGQRVLDSLFPCVQGGTTAIPGAFGCGKTVISQALSKYSNSDVIIYVGCGERGNEMSEVLRDFPELTVEIEGVTESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYNVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPDREGSVSIVGAVSPPGGDFSDPVTAATLGIVQVFWGLDKKLAQRKHFPSINWLISYSKYMRALDDFYEKNYPEFVPLRTKVKEILQEEEDLSEIVQLVGKASLAETDKITLEVAKLLKDDFLQQNSYSSYDRFCPFYKTVGMLKNIISFYDMSRHAVESTAQSDNKVTWNVIRDAMGNVLYQLSSMKFKDPVKDGEAKIKADFDQLLEDMSAAFRNLED DIP protein P31400 original sequence version: 92 mva-o76959_manse-1 2 9 unspecified role unspecified role unspecified role unspecified role manse Manduca sexta (Tobacco hawkmoth) Tobacco hornworm Tobacco hawkmoth 8 unspecified role unspecified role unspecified role unspecified role manse Manduca sexta (Tobacco hawkmoth) Tobacco hornworm Tobacco hawkmoth 3 unspecified role unspecified role unspecified role unspecified role manse Manduca sexta (Tobacco hawkmoth) Tobacco hornworm Tobacco hawkmoth 12 unspecified role unspecified role unspecified role unspecified role manse Manduca sexta (Tobacco hawkmoth) Tobacco hornworm Tobacco hawkmoth 11 unspecified role unspecified role unspecified role unspecified role manse Manduca sexta (Tobacco hawkmoth) Tobacco hornworm Tobacco hawkmoth 7 unspecified role unspecified role unspecified role unspecified role manse Manduca sexta (Tobacco hawkmoth) Tobacco hornworm Tobacco hawkmoth 10 unspecified role unspecified role unspecified role unspecified role manse Manduca sexta (Tobacco hawkmoth) Tobacco hornworm Tobacco hawkmoth 13 unspecified role unspecified role unspecified role unspecified role manse Manduca sexta (Tobacco hawkmoth) Tobacco hornworm Tobacco hawkmoth 5 unspecified role unspecified role unspecified role unspecified role manse Manduca sexta (Tobacco hawkmoth) Tobacco hornworm Tobacco hawkmoth 4 unspecified role unspecified role unspecified role unspecified role manse Manduca sexta (Tobacco hawkmoth) Tobacco hornworm Tobacco hawkmoth 6 unspecified role unspecified role unspecified role unspecified role manse Manduca sexta (Tobacco hawkmoth) Tobacco hornworm Tobacco hawkmoth 14 unspecified role unspecified role unspecified role unspecified role manse Manduca sexta (Tobacco hawkmoth) Tobacco hornworm Tobacco hawkmoth physical association physical association mva-o76959_manse-2 1 9 unspecified role unspecified role unspecified role unspecified role manse Manduca sexta (Tobacco hawkmoth) Tobacco hornworm Tobacco hawkmoth 8 unspecified role unspecified role unspecified role unspecified role manse Manduca sexta (Tobacco hawkmoth) Tobacco hornworm Tobacco hawkmoth 3 unspecified role unspecified role unspecified role unspecified role manse Manduca sexta (Tobacco hawkmoth) Tobacco hornworm Tobacco hawkmoth 12 unspecified role unspecified role unspecified role unspecified role manse Manduca sexta (Tobacco hawkmoth) Tobacco hornworm Tobacco hawkmoth 11 unspecified role unspecified role unspecified role unspecified role manse Manduca sexta (Tobacco hawkmoth) Tobacco hornworm Tobacco hawkmoth 7 unspecified role unspecified role unspecified role unspecified role manse Manduca sexta (Tobacco hawkmoth) Tobacco hornworm Tobacco hawkmoth 10 unspecified role unspecified role unspecified role unspecified role manse Manduca sexta (Tobacco hawkmoth) Tobacco hornworm Tobacco hawkmoth 13 unspecified role unspecified role unspecified role unspecified role manse Manduca sexta (Tobacco hawkmoth) Tobacco hornworm Tobacco hawkmoth 5 unspecified role unspecified role unspecified role unspecified role manse Manduca sexta (Tobacco hawkmoth) Tobacco hornworm Tobacco hawkmoth 4 unspecified role unspecified role unspecified role unspecified role manse Manduca sexta (Tobacco hawkmoth) Tobacco hornworm Tobacco hawkmoth 6 unspecified role unspecified role unspecified role unspecified role manse Manduca sexta (Tobacco hawkmoth) Tobacco hornworm Tobacco hawkmoth 14 unspecified role unspecified role unspecified role unspecified role manse Manduca sexta (Tobacco hawkmoth) Tobacco hornworm Tobacco hawkmoth physical association physical association