DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Structural biology. Mechanistic insight from the crystal structure of mitochondrial complex I. Structural biology. Mechanistic insight from the crystal structure of mitochondrial complex I. Science (New York, N.Y.) 2015 imex curation Zickermann V., Wirth C., Nasiri H., Siegmund K., Schwalbe H., Hunte C., Brandt U. Only protein-protein interactions yarli Yarrowia lipolytica (strain CLIB 122 / E 150) Yeast Candida lipolytica x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Zickermann V., Wirth C., Nasiri H., Siegmund K., Schwalbe H., Hunte C., Brandt U. DIP original experiment: DIP-265057X Science (New York, N.Y.) 2015 IMEx Structural biology. Mechanistic insight from the crystal structure of mitochondrial complex I. f2z6f1_yarli YALI0_D05467g protein protein yarli Yarrowia lipolytica (strain CLIB 122 / E 150) Yeast Candida lipolytica MLSRNLSKFARAGLIRPATTSTHTRLFSVSARRLAEIELTIDGHKVSIEAGSALIQACEKAGVTVPRYCYHDKLAIAGNCRMCLVDVERAPKPVASCAYPVAPGMVVRTDTERVKQARENVMEMMLQNHPLDCPVCDQGGECDLQDQSMRYGRDRGRFTEITGKRSTEDKNIGPLVKTSMNRCIHCTRCVRFANDIAGAPELGSSGRGNDMQIGTYLEKNLNTELSGNVIDLCPVGALTNKPYAFRARPWELKKTESIDVMDAVGSNIRIDSKGVEVMRVIPRVHEDVNEEWINDKSRFACDGLKTQRLTTPLIRVGDKFVNATWDDALSTIAKAYQQKAPKGDEFKAVAGALVEVESMVALKDMTNALGSENTTTDTPNGNSAPAHGITFRSNYLFNSSIAGIEDADAILLVGTNPRREAAVMNARIRKAWLRQELEIASVGPTLDATFDVAELGNTHADLEKALSGEFGEVLKNAKNPLIIVGSGITDREDAGAFFNTIGKFVESTPSVLNENWNGYNVLQRSASRAGAYDIGFTPSDEASKTTPKMVWLLGADEVAASDIPADAFVVYQGHNGDVGAQFADVVLPGAAYTEKAGTYVNTEGRSQISRAATGPPGGAREDWKILRAVSEYLGVALPYEDAYEVRDRLAEISPSLVRYDLVEPTVFGDVAVQHSLVGPNGSVTPSSAPLTETIENFYMTDSISRSSPTMAKSSIAFNKDNKKNQAFA DIP protein F2Z6F1 original sequence version: 23 nu2m_yarli NADH-ubiquinone oxidoreductase chain 2 ND2 NADH dehydrogenase subunit 2 protein protein yarli Yarrowia lipolytica (strain CLIB 122 / E 150) Yeast Candida lipolytica MLILAIISLITFVSMSKLSDNRAIIRLINIYLILVLVLDSFLYLLFLNNQTYTVMGELLIFNSFTFYIDMLIYFIMIVISSLYGYNLYNNNLYKTLFEPKKELIILFLINILGALLIVHSNDFITLFVAIELQSYSIYLITAIYNSSYKASKASMLYFFMGGILSILIAYSINTYYSVLNSYTLHSLDSLIINTLDLNLILIALSLGLLFKIGIAPLHKWLISIYENTPILITIYISLIPKISILSYLVLSNISINSLVISILAILTLLVGSVGGLLQIKIKRLLAFSGLTNAGYMMLLLLLNNNEFSYLYYITQYSISHLAIFMIIIFSIYYINYINNQYNPIIYVNQLKGLIHDNAYLVLSMAIVVFSFIGIPPLLGFFGKLNILMSILNNGYYFISIVLIVASLISALYYLYLLNVSIQDKNNILINSNETVSSVLSYILSSLIILITFGFIYNSLIIDIFNVYFN DIP protein Q9B6C8 original sequence version: 66 nu5m_yarli NADH-ubiquinone oxidoreductase chain 5 ND5 NADH dehydrogenase subunit 5 protein protein yarli Yarrowia lipolytica (strain CLIB 122 / E 150) Yeast Candida lipolytica MYNAISLIIILPCISWLFPLFFGRQLGYVFVTRMTSTLIIITTLITYYYFYQLLGNNNPINLELFNYLNIDYLDINYNFEIDALTITMLLAITTISSMVHIYSIGYMETDPHQVRFFSLLSMFTFWMIILVTGSNYFVLFVGWEFIGVTSYLLISFWVTRLQAMKSALSAVLMNRFGDAFFVLGLCVIAYVFGTLNYSTIFATAYLINTDLLVLIMLALFIAAMAKSAQFGLHNWLTLAMEGPTPVSSLLHAATLVTAGIYLLLRSANILEYTPTVLFIILWIGALTTLSAGLIAICSNDLKRIIALSTMSQLGMMTIAIGLSAYNLALFHLLGHAFFKALLFMSAGSIIHSILNESQDIRTYGGLLSYLPYTYICITIASLSLMAMPGLTGYYTKDIIIESTYGSYSISNYVVYWIAYLSAVLTCVYSMKILYLTFYSNPNNNTITYYNAHESNIYITLPMFILAIFAMFAGWILKDIYLGVGTDFVGTHILPNNFSYFDTEFSITQFYKLLPLISAILVSILIVVLNEFFAIVFNLNNKYINTVYSIFNQKLVSDQILNHFIIFKGLVTSGNIAHHVDKGSLYRLGPVGINRLLNKASYNVINLSSNTRSSLSMNSMLILITIVSLLLLVLVMNVNFIIVIPVLISILYILFS DIP protein Q9B6D3 original sequence version: 77 f2z619_yarli YALI0_F00924g protein protein yarli Yarrowia lipolytica (strain CLIB 122 / E 150) Yeast Candida lipolytica MLSLVRPAVTRSILRGAPGSMRLLSSTARLHAPATDSAINIYAGGSAAAAPPAGFRIHRPATWEESEEGALSKATKYFLLAEMFRGLYVVLEQFFRAPYTIYYPFEKGPVSPRFRGEHALRRYPSGEERCIACKLCEAICPALAITIDAEERIDGSRRTTKYDIDMTKCIYCGYCQESCPVDAIVETPNVEYATETREELLYNKEKLLANGDKWELELQYALDADAPYR DIP protein F2Z619 original sequence version: 26 nu6m_yarli NADH-ubiquinone oxidoreductase chain 6 ND6 NADH dehydrogenase subunit 6 protein protein yarli Yarrowia lipolytica (strain CLIB 122 / E 150) Yeast Candida lipolytica MMYLTYYFIEITIFLAILCTIFIISAKNPMVSILYMIALFVIAAMYLYLIGLGIFSLLYIMIYIGAIAVLFLFIITLLDINSTELSVKSNIRDLPLVLISLIVLTISGLMIYSNDSILINKLLEAFGNDYNTIITQDWFNIENTTLLTTIGNVLLTNNAFILLVLAIVLLLGIIGPISITMKHKE DIP protein Q9B6E9 original sequence version: 63 f2z6d7_yarli YALI0_F02123g protein protein yarli Yarrowia lipolytica (strain CLIB 122 / E 150) Yeast Candida lipolytica MLSRFARIGSMGIRPVAAARATFVTSARAAQAAPSWENIKDIRLDPKVHVDEVYEPIVNPADRYLQHVSDLHQYAKYIMAALPKYIQGFSVWKDELTLHVAPSAVIPVTTFLRDNTSTQYKSIIDITAVDYPSRENRFEVVYNFLSVRHNSRIRLKTYATEVTPVPSITCLYEGANWFEREAYDMYGVFFEGHPDLRRIMTDYGFEGHPLRKDFPLTGYTEVRWDEEKRRVVYEPLELTQAFRNFSAGSTAWEPVGPGRDDRPDSFKLPTPKPEEKEGDKK DIP protein F2Z6D7 original sequence version: 24 nu4m_yarli NADH-ubiquinone oxidoreductase chain 4 ND4 NADH dehydrogenase subunit 4 protein protein yarli Yarrowia lipolytica (strain CLIB 122 / E 150) Yeast Candida lipolytica MFLTSILLSSLYLFNRILAWQGNVKHFYLFASNLLLLFIVVLYINFNTFSNSFQFNFELFNSLNPFGLSNSDISNGLLFGIDGLSLTFILLTVLLIPLTLLGNWYNINFNSNLYYTLVLAIGLVILLNFWALDYISFYILFEATLPLLFILIHIYGSSDSERASFYVLMFTLSGSLFMLLSIVVISIVLNTTNFINHNLFVLSLDLQTIIWLGLFIAIMVKTPLFPIHVWLPVVHSESPLAGSMILAGLILKLALYAILRLLLPLLCEAQILYTPMIYIISLLTIILTSLATLRQIDLKVIIAYSSISHMGIAILGVCSNTSLGIYGSIVLGVAHGFVSPALFLIVGGILYDRYHIRIVNYYKGLTTYMPQLATYIIILSFANIGTPLTGNFTGEFLSLQGGFIRNPIIGGISCISVLLAAIYQLKLTNKLTGGISSIYMHRTNDVTIREKFIMNILIISTLIIGICPQIMYNLLYWTVNNYIYII DIP protein Q9B6D6 original sequence version: 73 nu1m_yarli NADH-ubiquinone oxidoreductase chain 1 ND1 NADH dehydrogenase subunit 1 protein protein yarli Yarrowia lipolytica (strain CLIB 122 / E 150) Yeast Candida lipolytica MIINIVEILIFLVCVLFSVAYLTVAERKTLAYMQRRLGPNFVGYYGLLQAFADAVKLLLKEIVLPKESNYIILVISPLITLITALIGWVVIPLGPGITLGELNLGILFSLAIGSLGVFGSLLSGWSSNSKYSLLGSIRSTAQLISYELILTSIFIIIIMFVSSLNITTIIETQRVVWYCIPLLPLLLIFFIASVAETARPPFDLTESESELVAGYFTEYSGSPFVFFFLAEYSNIILISAFNGYLLLGGYLSFNYSYLFNILFNDYSYVSFLFEGLINSSAYAIKLVFLMFSFIWVRAAFPRFTYDNLINFCWIILLPLLFGIFLIIPSTLYIFDSFPTLI DIP protein Q9B6E8 original sequence version: 74 f2z660_yarli NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial YALI0_B20372g protein protein yarli Yarrowia lipolytica (strain CLIB 122 / E 150) Yeast Candida lipolytica MLRTTLHKRGLARLSRGFATTQDATPKARQYGGLKDQDRIFQNLYDNYGWDLASARKQGDWYKTKELILKGDTWIIDEIKKSGLRGRGGAGFPSGLKWSFMNPPGWEKNEGPRYLVVNADEGEPGTCKDREIMRKDPHKLVEGCLLAGRAMNATAAYIYIRGEFYNEAAVLQTAINEAYAAGLIGKDACGSGYDFDVYIHRGMGAYVCGEETSLIESLEGKAGKPRLKPPFPAGVGLFGRPSTVTNVETVAVAPTILRRGGDWFASFGRERNSGTKLFCISGNVNEPCTVEEEMSIPLRELLEKHCGGIKGGWDNLLGVIPGGCSVPILPKNICEDVLMDFDALKDVQSGLGTAAVIVINKQQDVIRAIQRFAAFYKHESCGQCTPCREGTTWLLKAMDRFRTGQAKEREIDMLYELTKDIEGHTICALGDAAAWPIQGLIRNFRPEMETRMKKFHDEVGAVSVGGWMKDARVEKGKVVGAPLPGVHH DIP protein F2Z660 original sequence version: 23 f2z6c0_yarli YALI0_D00737g protein protein yarli Yarrowia lipolytica (strain CLIB 122 / E 150) Yeast Candida lipolytica MLRLIRPRLAALARPTTRAPQALNARTHIVSVHRNTENNNPSIPFEFSPENMKRAEEVIAKYPPQYKKAAVMPLLDIGQRQLGYTSISVMNYVAKLLEMPPMRVYEVATFYTMYNRTPMGRYHLQICTTTPCQLCGSDGIMEAVQNTLNIKPGETTKDNLFTLSEVECLGACVNAPMMAINDDYYEDLTPEGTVKLLEDCKAGKMPTPGPENHVRRDCEPASGQKVLLSKEPHNVADFLQEGI DIP protein F2Z6C0 original sequence version: 29 nu4lm_yarli NADH-ubiquinone oxidoreductase chain 4L ND4L NADH dehydrogenase subunit 4L protein protein yarli Yarrowia lipolytica (strain CLIB 122 / E 150) Yeast Candida lipolytica MFIGTIILVLSFLGFVFNRRNIILAFICLETMLLGINLILLRNSVLFDDISGSLFAIVIIILAGVESAIGLSLLVSYYRLRGVINSYGI DIP protein Q9B6D4 original sequence version: 67 nu3m_yarli NADH-ubiquinone oxidoreductase chain 3 ND3 NADH dehydrogenase subunit 3 protein protein yarli Yarrowia lipolytica (strain CLIB 122 / E 150) Yeast Candida lipolytica MNTFIIFIILIPIVGFALLAVNILLAVYKPYNEKLGAFECGLTSFNQTRLAFNAAFILVAILFLPFDLEISTLLPYVMSIYLVSNYGFTIVLLFLLILIIGFVYEINTNALKINKHNKPNTDSLIYKL DIP protein Q9B6C7 original sequence version: 64 f2z626_yarli YALI0_F17248g protein protein yarli Yarrowia lipolytica (strain CLIB 122 / E 150) Yeast Candida lipolytica MLRSAAARAVRAVRPRLSARYMATTALPQDPIPSGALGQKVPHVDESHQDLLFRTSHMVEDLETYDEDSPINTSDANTRIRAFTINFGPQHPAAHGVLRLILELSGEEIIRSDPHVGLLHRGTEKLIEYKTYMQALPYFDRLDYVSMMTNEQVFSLAVEKLLNVEVPLRGKYIRTMFGEITRVLNHLMSVCSHAMDVGALTPFLWGFEEREKLMEFYERVSGARLHAAYVRPGGVSQDLPAGLLDDIYMWATQFGDRLDEIEELLTDNRIWKLRTVNIGTVTAQDALNLGLSGPMLRGSGIPFDIRKNAPYDAYDKVDFDVPVGMNGDCYDRYLIRMAEFRQSLRIIEQCCNDMPAGAVKVEDFKINSPPRNLMKEDMEALIHHFLLYTKGYSVPPGETYTAIEAPKGEMGVYVVSDGSERPYKCKIRAPGFAHLGAFDHIARGHFLPDAVAIIGTMDLVFGEVDR DIP protein F2Z626 original sequence version: 27 q6c2q1_yarli YALI0_F06050g protein protein yarli Yarrowia lipolytica (strain CLIB 122 / E 150) Yeast Candida lipolytica MLRSQIGRLALRPTLVPATVIPQTRAYSAPAGTPRVSSSSMPTDFPLPSQQKPNSAVDYTLTTLDAVANWARQGSFWPVTFGLACCAVEMMHVSAPRYDQDRLGIIFRASPRQSDIMIVAGTLTNKMAPVLRQVYDQMPEPRWVISMGSCANGGGYYHFSYSVVRGCDRIVPVRRLRSRMSPHLRGPHVRRLPAPAKDAKHKDYPNVVPKVSIINV DIP protein Q6C2Q1 original sequence version: 66 f2z619_yarli-f2z626_yarli-1 1 5 unspecified role unspecified role unspecified role unspecified role yarli Yarrowia lipolytica (strain CLIB 122 / E 150) Yeast Candida lipolytica 15 unspecified role unspecified role unspecified role unspecified role yarli Yarrowia lipolytica (strain CLIB 122 / E 150) Yeast Candida lipolytica 7 unspecified role unspecified role unspecified role unspecified role yarli Yarrowia lipolytica (strain CLIB 122 / E 150) Yeast Candida lipolytica 14 unspecified role unspecified role unspecified role unspecified role yarli Yarrowia lipolytica (strain CLIB 122 / E 150) Yeast Candida lipolytica 2 unspecified role unspecified role unspecified role unspecified role yarli Yarrowia lipolytica (strain CLIB 122 / E 150) Yeast Candida lipolytica 11 unspecified role unspecified role unspecified role unspecified role yarli Yarrowia lipolytica (strain CLIB 122 / E 150) Yeast Candida lipolytica 10 unspecified role unspecified role unspecified role unspecified role yarli Yarrowia lipolytica (strain CLIB 122 / E 150) Yeast Candida lipolytica 6 unspecified role unspecified role unspecified role unspecified role yarli Yarrowia lipolytica (strain CLIB 122 / E 150) Yeast Candida lipolytica 4 unspecified role unspecified role unspecified role unspecified role yarli Yarrowia lipolytica (strain CLIB 122 / E 150) Yeast Candida lipolytica 12 unspecified role unspecified role unspecified role unspecified role yarli Yarrowia lipolytica (strain CLIB 122 / E 150) Yeast Candida lipolytica 8 unspecified role unspecified role unspecified role unspecified role yarli Yarrowia lipolytica (strain CLIB 122 / E 150) Yeast Candida lipolytica 13 unspecified role unspecified role unspecified role unspecified role yarli Yarrowia lipolytica (strain CLIB 122 / E 150) Yeast Candida lipolytica 3 unspecified role unspecified role unspecified role unspecified role yarli Yarrowia lipolytica (strain CLIB 122 / E 150) Yeast Candida lipolytica 9 unspecified role unspecified role unspecified role unspecified role yarli Yarrowia lipolytica (strain CLIB 122 / E 150) Yeast Candida lipolytica physical association physical association