DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Molecular basis of the dynamic structure of the TIM23 complex in the mitochondrial intermembrane space. Molecular basis of the dynamic structure of the TIM23 complex in the mitochondrial intermembrane space. Structure (London, England : 1993) 2014 imex curation Bajaj R., Jaremko Ł., Jaremko M., Becker S., Zweckstetter M. Only protein-protein interactions in vitro In vitro nmr nuclear magnetic resonance NMR NMR nmr predetermined predetermined participant predetermined Bajaj R., Jaremko Ł., Jaremko M., Becker S., Zweckstetter M. DIP original experiment: DIP-262299X Structure (London, England : 1993) 2014 IMEx Molecular basis of the dynamic structure of the TIM23 complex in the mitochondrial intermembrane space. Molecular basis of the dynamic structure of the TIM23 complex in the mitochondrial intermembrane space. Molecular basis of the dynamic structure of the TIM23 complex in the mitochondrial intermembrane space. Structure (London, England : 1993) 2014 imex curation Bajaj R., Jaremko Ł., Jaremko M., Becker S., Zweckstetter M. Only protein-protein interactions in vitro In vitro nmr nuclear magnetic resonance NMR NMR nmr predetermined predetermined participant predetermined Bajaj R., Jaremko Ł., Jaremko M., Becker S., Zweckstetter M. DIP original experiment: DIP-262297X Structure (London, England : 1993) 2014 IMEx Molecular basis of the dynamic structure of the TIM23 complex in the mitochondrial intermembrane space. Molecular basis of the dynamic structure of the TIM23 complex in the mitochondrial intermembrane space. Molecular basis of the dynamic structure of the TIM23 complex in the mitochondrial intermembrane space. Structure (London, England : 1993) 2014 imex curation Bajaj R., Jaremko Ł., Jaremko M., Becker S., Zweckstetter M. Only protein-protein interactions in vitro In vitro nmr nuclear magnetic resonance NMR NMR nmr predetermined predetermined participant predetermined Bajaj R., Jaremko Ł., Jaremko M., Becker S., Zweckstetter M. DIP original experiment: DIP-262300X Structure (London, England : 1993) 2014 IMEx Molecular basis of the dynamic structure of the TIM23 complex in the mitochondrial intermembrane space. Molecular basis of the dynamic structure of the TIM23 complex in the mitochondrial intermembrane space. Molecular basis of the dynamic structure of the TIM23 complex in the mitochondrial intermembrane space. Structure (London, England : 1993) 2014 imex curation Bajaj R., Jaremko Ł., Jaremko M., Becker S., Zweckstetter M. Only protein-protein interactions in vitro In vitro nmr nuclear magnetic resonance NMR NMR nmr predetermined predetermined participant predetermined Bajaj R., Jaremko Ł., Jaremko M., Becker S., Zweckstetter M. DIP original experiment: DIP-262298X Structure (London, England : 1993) 2014 IMEx Molecular basis of the dynamic structure of the TIM23 complex in the mitochondrial intermembrane space. tom22_yeast Mitochondrial import receptor subunit TOM22 MOM22 TOM22 MAS17 MAS22 YNL131W N1217 N1862 Mitochondrial 22 kDa outer membrane protein Translocase of outer membrane 22 kDa subunit Protein MAS17 Mitochondrial 17 kDa assembly protein protein protein yeast Saccharomyces cerevisiae Baker's yeast MVELTEIKDDVVQLDEPQFSRNQAIVEEKASATNNDVVDDEDDSDSDFEDEFDENETLLDRIVALKDIVPPGKRQTISNFFGFTSSFVRNAFTKSGNLAWTLTTTALLLGVPLSLSILAEQQLIEMEKTFDLQSDANNILAQGEKDAAATAN 6ACEC5D37D143CD3 6ACEC5D37D143CD3 tim23_yeast Mitochondrial import inner membrane translocase subunit TIM23 MIM23 MPI3 N3180 YNR017W TIM23 MAS6 Mitochondrial protein import protein 3 Mitochondrial protein import protein MAS6 Membrane import machinery protein MIM23 protein protein yeast Saccharomyces cerevisiae Baker's yeast MSWLFGDKTPTDDANAAVGGQDTTKPKELSLKQSLGFEPNINNIISGPGGMHVDTARLHPLAGLDKGVEYLDLEEEQLSSLEGSQGLIPSRGWTDDLCYGTGAVYLLGLGIGGFSGMMQGLQNIPPNSPGKLQLNTVLNHITKRGPFLGNNAGILALSYNIINSTIDALRGKHDTAGSIGAGALTGALFKSSKGLKPMGYSSAMVAAACAVWCSVKKRLLEK 08E5AB4F400F675B 08E5AB4F400F675B tim50_yeast Mitochondrial import inner membrane translocase subunit TIM50 TIM50 YPL063W protein protein yeast Saccharomyces cerevisiae Baker's yeast MLSILRNSVRLNSRALRVVPSAANTLTSVQASRRLLTSYSSFLQKETKDDKPKSILTDDMLFKAGVDVDEKGQGKNEETSGEGGEDKNEPSSKSEKSRRKRQTSTDIKREKYANWFYIFSLSALTGTAIYMARDWEPQESEELKKDIDNGYTLSLMYKRFKARFNSMFTYFQEPPFPDLLPPPPPPPYQRPLTLVITLEDFLVHSEWSQKHGWRTAKRPGADYFLGYLSQYYEIVLFSSNYMMYSDKIAEKLDPIHAFVSYNLFKEHCVYKDGVHIKDLSKLNRDLSKVIIIDTDPNSYKLQPENAIPMEPWNGEADDKLVRLIPFLEYLATQQTKDVRPILNSFEDKKNLAEEFDHRVKKLKDKFYGDHKSGGNWAMTALGLGNSLGGSTKFPLDLIHEEGQKNYLMFMKMIEEEKEKIRIQQEQMGGQTFTLKDYVEGNLPSPEEQMKIQLEKQKEVDALFEEEKKKKKIAESK 778D54F5C4ED27C8 778D54F5C4ED27C8 tim21_yeast Mitochondrial import inner membrane translocase subunit TIM21 TIM21 YGR033C protein protein yeast Saccharomyces cerevisiae Baker's yeast MSSSLPRSLLRLGHRKPLFPRYNTFVNSSVITHTSLLRTRLYSNGTGATSGKKDDKTRNKPKPLWPQVKSASTFTFSGILVIGAVGISAIVIYLILSELFSPSGDTQLFNRAVSMVEKNKDIRSLLQCDDGITGKERLKAYGELITNDKWTRNRPIVSTKKLDKEGRTHHYMRFHVESKKKIALVHLEAKESKQNYQPDFINMYVDVPGEKRYYLIKPKLHPVSNSKGFLGIRWGPRKD FC140F3034E5B5BB FC140F3034E5B5BB tim21-tim23-1 2 6 unspecified role unspecified role unspecified role unspecified role Region 1-96 Region 1-96 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 8 unspecified role unspecified role unspecified role unspecified role Region 103-225 Region 103-225 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction tim23-tim50-2 1 7 unspecified role unspecified role unspecified role unspecified role Region 164-361 Region 164-361 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 6 unspecified role unspecified role unspecified role unspecified role Region 1-96 Region 1-96 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction tim21-tim23-2 4 6 unspecified role unspecified role unspecified role unspecified role Region 1-13 Region 1-13 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain Region 61-96 Region 61-96 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain in vitro In vitro 8 unspecified role unspecified role unspecified role unspecified role Region 103-225 Region 103-225 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction tim23-tom22-1 3 5 unspecified role unspecified role unspecified role unspecified role Region 120-153 Region 120-153 sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined ecolx Escherichia coli 6 unspecified role unspecified role unspecified role unspecified role Region 1-96 Region 1-96 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction