HPIDb Host Pathogen Interaction database http://www.agbase.msstate.edu/hpi/main.html Mycoplasma hyorhinis infection promotes NF-κB-dependent migration of gastric cancer cells. Mycoplasma hyorhinis infection promotes NF-κB-dependent migration of gastric cancer cells. Cancer research 2014 imex curation Duan H., Chen L., Qu L., Yang H., Song SW., Han Y., Ye M., Chen W., He X., Shou C. xianglh992004@163.com 05-Sep-2017: Contacted by IntAct-Help. Only protein-protein interactions imex curation in vitro In vitro pull down pull down ms participant Identification by mass spectrometry ms participant Duan H., Chen L., Qu L., Yang H., Song SW., Han Y., Ye M., Chen W., He X., Shou C. xianglh992004@163.com Accepted 2017-AUG-17 AT 11:13 BST AT 11:13 BST by MGT Cancer research 2014 imex curation Mycoplasma hyorhinis infection promotes NF-κB-dependent migration of gastric cancer cells. Mycoplasma hyorhinis infection promotes NF-κB-dependent migration of gastric cancer cells. Cancer research 2014 imex curation Duan H., Chen L., Qu L., Yang H., Song SW., Han Y., Ye M., Chen W., He X., Shou C. xianglh992004@163.com 05-Sep-2017: Contacted by IntAct-Help. Only protein-protein interactions imex curation human-mgc-803 Homo sapiens mgc-803 Human-poorly differentiated human gastric adenocarcinoma MGC803 Original paper: - no pmid available. K.H. Wang The establishment and biological characteristics of a poorly differentiated human gastric adenocarcinoma MGC803 cell line. Acta Biol. Exp. Sin., 16 (1983), pp. 257–267 anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Duan H., Chen L., Qu L., Yang H., Song SW., Han Y., Ye M., Chen W., He X., Shou C. xianglh992004@163.com Accepted 2017-AUG-17 AT 11:13 BST AT 11:13 BST by MGT Cancer research 2014 imex curation Mycoplasma hyorhinis infection promotes NF-κB-dependent migration of gastric cancer cells. Mycoplasma hyorhinis infection promotes NF-κB-dependent migration of gastric cancer cells. Cancer research 2014 imex curation Duan H., Chen L., Qu L., Yang H., Song SW., Han Y., Ye M., Chen W., He X., Shou C. xianglh992004@163.com 05-Sep-2017: Contacted by IntAct-Help. Only protein-protein interactions imex curation in vitro In vitro pull down pull down western blot western blot Immuno blot Immuno blot Duan H., Chen L., Qu L., Yang H., Song SW., Han Y., Ye M., Chen W., He X., Shou C. xianglh992004@163.com Accepted 2017-AUG-17 AT 11:13 BST AT 11:13 BST by MGT Cancer research 2014 imex curation Mycoplasma hyorhinis infection promotes NF-κB-dependent migration of gastric cancer cells. Mycoplasma hyorhinis infection promotes NF-κB-dependent migration of gastric cancer cells. Cancer research 2014 imex curation Duan H., Chen L., Qu L., Yang H., Song SW., Han Y., Ye M., Chen W., He X., Shou C. xianglh992004@163.com 05-Sep-2017: Contacted by IntAct-Help. Only protein-protein interactions imex curation in vitro In vitro elisa enzyme linked immunosorbent assay ELISA ELISA elisa antibody detection identification by antibody antibody detection Duan H., Chen L., Qu L., Yang H., Song SW., Han Y., Ye M., Chen W., He X., Shou C. xianglh992004@163.com Accepted 2017-AUG-17 AT 11:13 BST AT 11:13 BST by MGT Cancer research 2014 imex curation Mycoplasma hyorhinis infection promotes NF-κB-dependent migration of gastric cancer cells. Mycoplasma hyorhinis infection promotes NF-κB-dependent migration of gastric cancer cells. Cancer research 2014 imex curation Duan H., Chen L., Qu L., Yang H., Song SW., Han Y., Ye M., Chen W., He X., Shou C. xianglh992004@163.com 05-Sep-2017: Contacted by IntAct-Help. Only protein-protein interactions imex curation human-ags Homo sapiens caucasian gastric adenocarcinoma cell line AGS ags Human caucasian gastric adenocarcinoma cell line AGS Derived from an adenocarcinoma of the stomach of a 54 year old Caucasian female with no prior anti-cancer treatment. anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Duan H., Chen L., Qu L., Yang H., Song SW., Han Y., Ye M., Chen W., He X., Shou C. xianglh992004@163.com Accepted 2017-AUG-17 AT 11:13 BST AT 11:13 BST by MGT Cancer research 2014 imex curation Mycoplasma hyorhinis infection promotes NF-κB-dependent migration of gastric cancer cells. Mycoplasma hyorhinis infection promotes NF-κB-dependent migration of gastric cancer cells. Cancer research 2014 imex curation Duan H., Chen L., Qu L., Yang H., Song SW., Han Y., Ye M., Chen W., He X., Shou C. xianglh992004@163.com 05-Sep-2017: Contacted by IntAct-Help. Only protein-protein interactions imex curation human-ags Homo sapiens caucasian gastric adenocarcinoma cell line AGS ags Human caucasian gastric adenocarcinoma cell line AGS Derived from an adenocarcinoma of the stomach of a 54 year old Caucasian female with no prior anti-cancer treatment. confocal microscopy confocal microscopy immunostaining immunostaining Duan H., Chen L., Qu L., Yang H., Song SW., Han Y., Ye M., Chen W., He X., Shou C. xianglh992004@163.com Accepted 2017-AUG-17 AT 11:13 BST AT 11:13 BST by MGT Cancer research 2014 imex curation Mycoplasma hyorhinis infection promotes NF-κB-dependent migration of gastric cancer cells. Mycoplasma hyorhinis infection promotes NF-κB-dependent migration of gastric cancer cells. Cancer research 2014 imex curation Duan H., Chen L., Qu L., Yang H., Song SW., Han Y., Ye M., Chen W., He X., Shou C. xianglh992004@163.com 05-Sep-2017: Contacted by IntAct-Help. Only protein-protein interactions imex curation human-mgc-803 Homo sapiens mgc-803 Human-poorly differentiated human gastric adenocarcinoma MGC803 Original paper: - no pmid available. K.H. Wang The establishment and biological characteristics of a poorly differentiated human gastric adenocarcinoma MGC803 cell line. Acta Biol. Exp. Sin., 16 (1983), pp. 257–267 confocal microscopy confocal microscopy immunostaining immunostaining Duan H., Chen L., Qu L., Yang H., Song SW., Han Y., Ye M., Chen W., He X., Shou C. xianglh992004@163.com Accepted 2017-AUG-17 AT 11:13 BST AT 11:13 BST by MGT Cancer research 2014 imex curation anxa2_human Annexin A2 ANXA2 ANX2 ANX2L4 CAL1H LPC2D Annexin-2 Annexin II Lipocortin II Calpactin I heavy chain Chromobindin-8 p36 Protein I Placental anticoagulant protein IV Calpactin-1 heavy chain protein protein human Homo sapiens Human MSTVHEILCKLSLEGDHSTPPSAYGSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKELASALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARDLYDAGVKRKGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKGDYQKALLYLCGGDD 5126E1337A0CBEA1 p37_mychr High affinity transport system protein p37 p37 protein protein Mycoplasma hyorhinis Mycoplasma hyorhinis MLKKLKNFILFSSIFSPIAFAISCSNTGVVKQEDVSVSQGQWDKSITFGVSEAWLNKKKGGEKVNKEVINTFLENFKKEFNKLKNANDKTKNFDDVDFKVTPIQDFTVLLNNLSTDNPELDFGINASGKLVEFLKNNPGIITPALETTTNSFVFDKEKDKFYVDGTDSDPLVKIAKEINKIFVETPYASWTDENHKWNGNVYQSVYDPTVQANFYRGMIWIKGNDETLAKIKKAWNDKDWNTFRNFGILHGKDNSFSKFKLEETILKNHFQNKFTTLNEDRSAHPNAYKQKSADTLGTLDDFHIAFSEEGSFAWTHNKSATKPFETKANEKMEALIVTNPIPYDVGVFRKSVNQLEQNLIVQTFINLAKNKQDTYGPLLGYNGYKKIDNFQKEIVEVYEKAIK F924180309DBFFDF egfr_human Epidermal growth factor receptor ERBB1 EGFR Receptor tyrosine-protein kinase erbB-1 Proto-oncogene c-ErbB-1 ERBB HER1 protein protein human Homo sapiens Human MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA DIP protein P00533 original sequence version: 213 DIP protein P00533 original sequence version: 214 DIP protein P00533 original sequence version: 119 DIP protein P00533 original sequence version: 207 DIP protein P00533 original sequence version: 132 DIP protein P00533-1 original sequence version: 197 DIP protein P00533 original sequence version: 163 DIP protein P00533-1 original sequence version: 159 DIP protein P00533 original sequence version: 184 DIP protein P00533-1 original sequence version: 174 DIP protein P00533-1 original sequence version: 191 DIP protein P00533 original sequence version: 218 DIP protein P00533 original sequence version: 221 DIP protein P00533-1 original sequence version: 221 DIP protein P00533 original sequence version: 226 DIP protein P00533 original sequence version: 166 DIP protein P00533-1 original sequence version: 166 DIP protein P00533 original sequence version: 194 DIP protein P00533-1 original sequence version: 194 DIP protein P00533-1 original sequence version: 224 DIP protein P00533 original sequence version: 189 DIP protein P00533-1 original sequence version: 207 DIP protein P00533 original sequence version: 177 DIP protein P00533 original sequence version: 168 D8A2A50B4EFB6ED2 p37-anxa2-4 1 8 unspecified role unspecified role prey prey human-mgc-803 Homo sapiens mgc-803 Human-poorly differentiated human gastric adenocarcinoma MGC803 Original paper: - no pmid available. K.H. Wang The establishment and biological characteristics of a poorly differentiated human gastric adenocarcinoma MGC803 cell line. Acta Biol. Exp. Sin., 16 (1983), pp. 257–267 9 unspecified role unspecified role bait bait gst tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association 4A p37-anxa2-5 2 8 unspecified role unspecified role prey prey 9 unspecified role unspecified role bait bait physical association physical association 4B p37-anxa2-6 6 8 unspecified role unspecified role neutral component neutral component 9 unspecified role unspecified role neutral component neutral component colocalization colocalization 4C, suppl 4D p37-anxa2-7 3 8 unspecified role unspecified role prey prey his tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human-mgc-803 Homo sapiens mgc-803 Human-poorly differentiated human gastric adenocarcinoma MGC803 Original paper: - no pmid available. K.H. Wang The establishment and biological characteristics of a poorly differentiated human gastric adenocarcinoma MGC803 cell line. Acta Biol. Exp. Sin., 16 (1983), pp. 257–267 9 unspecified role unspecified role bait bait gst tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain chemical synthesis Chemical synthesis (Chemical synthesis) physical association physical association 4D p37-anxa2-8 3 8 unspecified role unspecified role prey prey region required to bind necessary binding region required to bind certain certain sequence position certain certain certain sequence position certain his tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human-mgc-803 Homo sapiens mgc-803 Human-poorly differentiated human gastric adenocarcinoma MGC803 Original paper: - no pmid available. K.H. Wang The establishment and biological characteristics of a poorly differentiated human gastric adenocarcinoma MGC803 cell line. Acta Biol. Exp. Sin., 16 (1983), pp. 257–267 9 unspecified role unspecified role bait bait gst tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association 4D p37-anxa2-9 4 8 unspecified role unspecified role bait bait region required to bind necessary binding region required to bind certain certain sequence position certain certain certain sequence position certain chemical synthesis Chemical synthesis (Chemical synthesis) 9 unspecified role unspecified role prey prey gst tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined region required to bind necessary binding region required to bind certain certain sequence position certain certain certain sequence position certain chemical synthesis Chemical synthesis (Chemical synthesis) 35 38 direct interaction direct interaction 4E anxa2-p37-6 4 9 competitor competitor competitor prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain chemical synthesis Chemical synthesis (Chemical synthesis) 8 unspecified role unspecified role bait bait his tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined ecoli Escherichia coli (strain K12) 9 unspecified role unspecified role prey prey gst tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association 4F p37-anxa2-10 2 10 unspecified role unspecified role prey prey 8 unspecified role unspecified role prey prey 9 unspecified role unspecified role bait bait physical association physical association 6B anxa2-p37-7 6 10 unspecified role unspecified role neutral component neutral component 8 unspecified role unspecified role neutral component neutral component 9 unspecified role unspecified role neutral component neutral component colocalization colocalization 6C anxa2-egfr-1 7 10 unspecified role unspecified role neutral component neutral component 8 unspecified role unspecified role neutral component neutral component 9 unspecified role unspecified role neutral component neutral component colocalization colocalization 6C p37-anxa2-11 2 8 unspecified role unspecified role bait bait 9 unspecified role unspecified role prey prey physical association physical association 4B anxa2-egfr-2 5 10 unspecified role unspecified role bait bait 8 unspecified role unspecified role prey prey region optyr O4'-phospho-L-tyrosine (2S)-2-amino-3-(4-phosphonooxyphenyl)propanoic acid 2-azanyl-3-(4-phosphonooxyphenyl)propanoic acid MOD_RES Phosphotyrosine O4-phosphotyrosine tyrosine phosphate 2-amino-3-(4-hydroxyphenyl)propanoic acid 4'-phosphate O4'-phospho-L-tyrosine O4'-phosphorylated L-tyrosine OPTyr Phospho Phospho Tyrosinyl Phosphorylation phosphorylationy undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined observed-ptm observed-ptm observed ptm observed-ptm physical association physical association 6D M. hyorhinis infection anxa2-p37-8 6 8 unspecified role unspecified role neutral component neutral component 9 unspecified role unspecified role neutral component neutral component gst tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined colocalization colocalization suppl 4E anxa2-p37-9 7 8 unspecified role unspecified role neutral component neutral component 9 unspecified role unspecified role neutral component neutral component colocalization colocalization suppl 4D anxa2-p37-10 7 8 unspecified role unspecified role neutral component neutral component 9 unspecified role unspecified role neutral component neutral component gst tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined colocalization colocalization suppl 4E