DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu (19)F NMR reveals multiple conformations at the dimer interface of the nonstructural protein 1 effector domain from influenza A virus. (19)F NMR reveals multiple conformations at the dimer interface of the nonstructural protein 1 effector domain from influenza A virus. Structure (London, England : 1993) 2014 imex curation Aramini JM., Hamilton K., Ma LC., Swapna GV., Leonard PG., Ladbury JE., Krug RM., Montelione GT. Only protein-protein interactions ecolx Escherichia coli crosslink cross-linking study crosslink weight by comassie molecular weight estimation by coomasie staining weight by comassie Aramini JM., Hamilton K., Ma LC., Swapna GV., Leonard PG., Ladbury JE., Krug RM., Montelione GT. DIP original experiment: DIP-260607X Structure (London, England : 1993) 2014 IMEx (19)F NMR reveals multiple conformations at the dimer interface of the nonstructural protein 1 effector domain from influenza A virus. (19)F NMR reveals multiple conformations at the dimer interface of the nonstructural protein 1 effector domain from influenza A virus. (19)F NMR reveals multiple conformations at the dimer interface of the nonstructural protein 1 effector domain from influenza A virus. Structure (London, England : 1993) 2014 imex curation Aramini JM., Hamilton K., Ma LC., Swapna GV., Leonard PG., Ladbury JE., Krug RM., Montelione GT. Only protein-protein interactions ecolx Escherichia coli nmr nuclear magnetic resonance NMR NMR nmr predetermined predetermined participant predetermined Aramini JM., Hamilton K., Ma LC., Swapna GV., Leonard PG., Ladbury JE., Krug RM., Montelione GT. DIP original experiment: DIP-260608X Structure (London, England : 1993) 2014 IMEx (19)F NMR reveals multiple conformations at the dimer interface of the nonstructural protein 1 effector domain from influenza A virus. (19)F NMR reveals multiple conformations at the dimer interface of the nonstructural protein 1 effector domain from influenza A virus. (19)F NMR reveals multiple conformations at the dimer interface of the nonstructural protein 1 effector domain from influenza A virus. Structure (London, England : 1993) 2014 imex curation Aramini JM., Hamilton K., Ma LC., Swapna GV., Leonard PG., Ladbury JE., Krug RM., Montelione GT. Only protein-protein interactions ecolx Escherichia coli solution sedimentati cosedimentation in solution solution sedimentati predetermined predetermined participant predetermined Aramini JM., Hamilton K., Ma LC., Swapna GV., Leonard PG., Ladbury JE., Krug RM., Montelione GT. DIP original experiment: DIP-260606X Structure (London, England : 1993) 2014 IMEx (19)F NMR reveals multiple conformations at the dimer interface of the nonstructural protein 1 effector domain from influenza A virus. ns1_i72a2 Non-structural protein 1 NS NS1A protein protein i72a2 Influenza A virus (strain A/Udorn/307/1972 H3N2) MDSNTVSSFQVDCFLWHVRKQVVDQELGDAPFLDRLRRDQKSLRGRGSTLGLNIEAATHVGKQIVEKILKEESDEALKMTMASTPASRYITDMTIEELSRDWFMLMPKQKVEGPLCIRIDQAIMDKNIMLKANFSVIFDRLETLILLRAFTEEGAIVGEISPLPSFPGHTIEDVKNAIGVLIGGLEWNDNTVRVSKTLQRFAWGSSNENGRPPLTPKQKRKMARTARSKVRRDKMAD DIP protein P03495 original sequence version: 109 DIP protein P03495 original sequence version: 73 DIP protein P03495 original sequence version: 88 DIP protein P03495 original sequence version: 101 14D0308795627E5E ns-9 3 4 unspecified role unspecified role unspecified role unspecified role Region 85-215 Region 85-215 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction ns-10 1 4 unspecified role unspecified role unspecified role unspecified role Region 85-215 Region 85-215 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain P03495:p.[Cys116Ser;Gly183Cys] C116S/G183C mutation mutation certain certain sequence position certain certain certain sequence position certain G C certain certain sequence position certain certain certain sequence position certain C S This feature has been corrected as a result of our quality control procedures. The original label was 'C116S/G183C'. Wed May 02 16:04:42 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'cys116ser,gly183cys' Tue Jun 30 18:47:41 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Cys116Ser;Gly183Cys]' ecolx Escherichia coli direct interaction direct interaction ns-11 2 4 unspecified role unspecified role unspecified role unspecified role Region 85-215 Region 85-215 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain P03495:p.Lys110Ala K110A mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain K A This feature has been corrected as a result of our quality control procedures. The original label was 'K110A'. Wed May 02 17:37:32 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'lys110ala' Tue Jun 30 16:23:45 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Lys110Ala' 5-Fluoro 5-Fluoro 5'-fluoro-l-tryptophan 5'-fluoro-L-tryptophan 5-fluorotryptophan certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction