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<entrySet xmlns="http://psi.hupo.org/mi/mif300" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://psi.hupo.org/mi/mif300 https://raw.githubusercontent.com/HUPO-PSI/miXML/master/3.0/src/MIF300.xsd" level="3" version="0" minorVersion="0">
  <entry>
    <source releaseDate="2022-02-03">
      <names>
        <shortLabel>DIP</shortLabel>
        <fullName>Database of Interacting Proteins</fullName>
      </names>
      <xref>
        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="identity" refTypeAc="MI:0356"/>
        <secondaryRef db="pubmed" dbAc="MI:0446" id="14681454" refType="identity" refTypeAc="MI:0356"/>
        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1579232" refType="identity" refTypeAc="MI:0356"/>
      </xref>
      <attributeList>
        <attribute name="postaladdress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
        <attribute name="url" nameAc="MI:0614">http://dip.doe-mbi.ucla.edu/</attribute>
        <attribute name="contact-email" nameAc="MI:0634">dip@mbi.ucla.edu</attribute>
      </attributeList>
    </source>
    <experimentList>
      <experimentDescription id="1">
        <names>
          <fullName>Structural insights into membrane interaction and caveolar targeting of dynamin-like EHD2.</fullName>
        </names>
        <bibref>
          <xref>
            <primaryRef db="pubmed" dbAc="MI:0446" id="24508342" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="doi" dbAc="MI:0574" id="10.1016/j.str.2013.12.015" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-16092887" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="imex" dbAc="MI:0670" id="IM-22334" refType="imex-primary" refTypeAc="MI:0662"/>
          </xref>
          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">Structural insights into membrane interaction and caveolar targeting of dynamin-like EHD2.</attribute>
            <attribute name="journal" nameAc="MI:0885">Structure (London, England : 1993)</attribute>
            <attribute name="publication year" nameAc="MI:0886">2014</attribute>
            <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
            <attribute name="author-list" nameAc="MI:0636">Shah C.,  Hegde BG.,  Morén B.,  Behrmann E.,  Mielke T.,  Moenke G.,  Spahn CM.,  Lundmark R.,  Daumke O.,  Langen R.</attribute>
            <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
          </attributeList>
        </bibref>
        <xref>
          <primaryRef db="imex" dbAc="MI:0670" id="IM-22334" refType="imex-primary" refTypeAc="MI:0662"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-259694X" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="wwpdb" dbAc="MI:0805" id="4CID" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="pubmed" dbAc="MI:0446" id="24508342" refType="primary-reference" refTypeAc="MI:0358"/>
          <secondaryRef db="doi" dbAc="MI:0574" id="10.1016/j.str.2013.12.015" refType="primary-reference" refTypeAc="MI:0358"/>
        </xref>
        <hostOrganismList>
          <hostOrganism ncbiTaxId="562">
            <names>
              <shortLabel>ecolx</shortLabel>
              <fullName>Escherichia coli</fullName>
            </names>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>x-ray diffraction</shortLabel>
            <fullName>x-ray crystallography</fullName>
            <alias type="go synonym" typeAc="MI:0303">X-ray</alias>
            <alias type="synonym" typeAc="MI:1041">X-ray</alias>
            <alias type="synonym" typeAc="MI:1041">x-ray diffraction</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0114" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1272" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>predetermined</shortLabel>
            <fullName>predetermined participant</fullName>
            <alias type="synonym" typeAc="MI:1041">predetermined</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Shah C., Hegde BG., Morén B., Behrmann E., Mielke T., Moenke G., Spahn CM., Lundmark R., Daumke O., Langen R.</attribute>
          <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-259694X</attribute>
          <attribute name="journal" nameAc="MI:0885">Structure (London, England : 1993)</attribute>
          <attribute name="publication year" nameAc="MI:0886">2014</attribute>
          <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
          <attribute name="title" nameAc="MI:1091">Structural insights into membrane interaction and caveolar targeting of dynamin-like EHD2.</attribute>
        </attributeList>
      </experimentDescription>
    </experimentList>
    <interactorList>
      <interactor id="2">
        <names>
          <shortLabel>ehd2_mouse</shortLabel>
          <fullName>EH domain-containing protein 2</fullName>
          <alias type="gene name" typeAc="MI:0301">Ehd2</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q8BH64" version="SP_57" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q8BL28" version="SP_57" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000096397" version="SP_168" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1994334" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_011248884.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_694708.2"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-46806N"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSG00000074364" version="SP_168" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000098799" version="SP_168" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005509" version="SP_168"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005524" version="SP_168"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005525" version="SP_168"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005769" version="SP_168"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" version="SP_168"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" version="SP_168"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005901" version="SP_168"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006897" version="SP_168"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0015630" version="SP_168"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016020" version="SP_168"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016197" version="SP_168"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016787" version="SP_168"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0019898" version="SP_168"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0019904" version="SP_168"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030139" version="SP_168"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030866" version="SP_168"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032456" version="SP_168"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" version="SP_168"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043231" version="SP_168"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045171" version="SP_168"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0048471" version="SP_168"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0055038" version="SP_168"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0060271" version="SP_168"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0072659" version="SP_168"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097320" version="SP_168"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1901741" version="SP_168"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:2001137" version="SP_168"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000261" version="SP_168"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002048" version="SP_168"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011992" version="SP_168"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR018247" version="SP_168"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR022812" version="SP_168"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR027417" version="SP_168"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR029945" version="SP_168"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR030381" version="SP_168"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR031692" version="SP_168"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR040990" version="SP_168"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2QPT" version="SP_168"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4CID" version="SP_168"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-983231" version="SP_168"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="10090">
          <names>
            <shortLabel>mouse</shortLabel>
            <fullName>Mus musculus</fullName>
            <alias type="synonym" typeAc="MI:1041">Mouse</alias>
          </names>
        </organism>
        <sequence>MFSWLKKGGARGQRPEAIRTVTSSLKELYRTKLLPLEEHYRFGSFHSPALEDADFDGKPMVLVAGQYSTGKTSFIQYLLEQEVPGSRVGPEPTTDCFVAVMHGETEGTVPGNALVVDPEKPFRKLNPFGNTFLNRFMCAQLPNQVLESISIIDTPGILSGAKQRVSRGYDFPAVLRWFAERVDLIILLFDAHKLEISDEFSEAIGALRGHEDKIRVVLNKADMVETQQLMRVYGALMWALGKVVGTPEVLRVYIGSFWSQPLLVPDNRRLFELEEQDLFRDIQGLPRHAALRKLNDLVKRARLVRVHAYIISYLKKEMPTVFGKENKKKQLILKLPVIFAKIQLEHHISPGDFPDCQKMQELLMAHDFTKFHSLKPKLLEALDDMLAQDIAKLMPLLRQEELESVEAGVQGGAFEGTRMGPFVERGPDEAIEDGEEGSEDDAEWVVTKDKSKYDEIFYNLAPADGKLSGSKAKTWMVGTKLPNSVLGRIWKLSDVDRDGMLDDEEFALASHLIEAKLEGHGLPTNLPRRLVPPSKRRQKGSAE</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein Q8BH64 original sequence version: 101</attribute>
          <attribute name="remark-internal">DIP protein Q8BH64 original sequence version: 86</attribute>
          <attribute name="remark-internal">DIP protein Q8BH64 original sequence version: 109</attribute>
          <attribute name="crc64">47637795B0B1096E</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="3" imexId="IM-22334-1">
        <names>
          <shortLabel>ehd2-5</shortLabel>
        </names>
        <xref>
          <primaryRef db="dip" dbAc="MI:0465" id="DIP-191014E" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-16092907" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-22334-1" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="4">
            <interactorRef>2</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>unspecified role</shortLabel>
                  <fullName>unspecified role</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="562">
                <names>
                  <shortLabel>ecolx</shortLabel>
                  <fullName>Escherichia coli</fullName>
                </names>
              </hostOrganism>
            </hostOrganismList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>direct interaction</shortLabel>
            <fullName>direct interaction</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
      </interaction>
    </interactionList>
  </entry>
</entrySet>