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  <entry>
    <source releaseDate="2022-02-03">
      <names>
        <shortLabel>DIP</shortLabel>
        <fullName>Database of Interacting Proteins</fullName>
      </names>
      <xref>
        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="identity" refTypeAc="MI:0356"/>
        <secondaryRef db="pubmed" dbAc="MI:0446" id="14681454" refType="identity" refTypeAc="MI:0356"/>
        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1579232" refType="identity" refTypeAc="MI:0356"/>
      </xref>
      <attributeList>
        <attribute name="postaladdress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
        <attribute name="url" nameAc="MI:0614">http://dip.doe-mbi.ucla.edu/</attribute>
        <attribute name="contact-email" nameAc="MI:0634">dip@mbi.ucla.edu</attribute>
      </attributeList>
    </source>
    <experimentList>
      <experimentDescription id="1">
        <names>
          <fullName>Preferential recognition of avian-like receptors in human influenza A H7N9 viruses.</fullName>
        </names>
        <bibref>
          <xref>
            <primaryRef db="pubmed" dbAc="MI:0446" id="24311689" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="doi" dbAc="MI:0574" id="10.1126/science.1243761" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-16084190" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="imex" dbAc="MI:0670" id="IM-24252" refType="imex-primary" refTypeAc="MI:0662"/>
          </xref>
          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">Preferential recognition of avian-like receptors in human influenza A H7N9 viruses.</attribute>
            <attribute name="journal" nameAc="MI:0885">Science (New York, N.Y.)</attribute>
            <attribute name="publication year" nameAc="MI:0886">2013</attribute>
            <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
            <attribute name="author-list" nameAc="MI:0636">Xu R.,  de Vries RP.,  Zhu X.,  Nycholat CM.,  McBride R.,  Yu W.,  Paulson JC.,  Wilson IA.</attribute>
            <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
          </attributeList>
        </bibref>
        <xref>
          <primaryRef db="imex" dbAc="MI:0670" id="IM-24252" refType="imex-primary" refTypeAc="MI:0662"/>
          <secondaryRef db="wwpdb" dbAc="MI:0805" id="4N5K" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="wwpdb" dbAc="MI:0805" id="4N61" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="wwpdb" dbAc="MI:0805" id="4N62" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="wwpdb" dbAc="MI:0805" id="4N63" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="wwpdb" dbAc="MI:0805" id="4N5J" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="wwpdb" dbAc="MI:0805" id="4N64" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-265007X" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="wwpdb" dbAc="MI:0805" id="4N60" refType="identity" refTypeAc="MI:0356"/>
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          <secondaryRef db="doi" dbAc="MI:0574" id="10.1126/science.1243761" refType="primary-reference" refTypeAc="MI:0358"/>
        </xref>
        <hostOrganismList>
          <hostOrganism ncbiTaxId="7111">
            <names>
              <shortLabel>trini</shortLabel>
              <fullName>Trichoplusia ni (Cabbage looper)</fullName>
              <alias type="synonym" typeAc="MI:1041">Cabbage looper</alias>
            </names>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>x-ray diffraction</shortLabel>
            <fullName>x-ray crystallography</fullName>
            <alias type="go synonym" typeAc="MI:0303">X-ray</alias>
            <alias type="synonym" typeAc="MI:1041">X-ray</alias>
            <alias type="synonym" typeAc="MI:1041">x-ray diffraction</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0114" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1272" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>predetermined</shortLabel>
            <fullName>predetermined participant</fullName>
            <alias type="synonym" typeAc="MI:1041">predetermined</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Xu R., de Vries RP., Zhu X., Nycholat CM., McBride R., Yu W., Paulson JC., Wilson IA.</attribute>
          <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-265007X</attribute>
          <attribute name="journal" nameAc="MI:0885">Science (New York, N.Y.)</attribute>
          <attribute name="publication year" nameAc="MI:0886">2013</attribute>
          <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
          <attribute name="title" nameAc="MI:1091">Preferential recognition of avian-like receptors in human influenza A H7N9 viruses.</attribute>
        </attributeList>
      </experimentDescription>
    </experimentList>
    <interactorList>
      <interactor id="2">
        <names>
          <shortLabel>r4nn21_9infa</shortLabel>
          <fullName>Hemagglutinin</fullName>
          <alias type="gene name" typeAc="MI:0301">HA</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="R4NN21" version="15" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-16084217" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016021" version="TrEMBL_62"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016324" version="TrEMBL_62"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0019031" version="TrEMBL_62"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0019062" version="TrEMBL_62"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0019064" version="TrEMBL_62"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0020002" version="TrEMBL_62"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0039654" version="TrEMBL_62"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0046761" version="TrEMBL_62"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0046789" version="TrEMBL_62"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0046872" version="TrEMBL_62"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0055036" version="TrEMBL_62"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0075512" version="TrEMBL_62"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000149" version="TrEMBL_62"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001364" version="TrEMBL_62"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR008980" version="TrEMBL_62"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013828" version="TrEMBL_62"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4LN3" version="TrEMBL_62"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4LN4" version="TrEMBL_62"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4LN6" version="TrEMBL_62"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4LN8" version="TrEMBL_62"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4N5J" version="TrEMBL_62"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4N5K" version="TrEMBL_62"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4N60" version="TrEMBL_62"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4N61" version="TrEMBL_62"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4N62" version="TrEMBL_62"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4N63" version="TrEMBL_62"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4N64" version="TrEMBL_62"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5T6S" version="TrEMBL_62"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5VAG" version="TrEMBL_62"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5VJK" version="TrEMBL_62"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5VJL" version="TrEMBL_62"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5VJM" version="TrEMBL_62"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5XKU" version="TrEMBL_62"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6ICW" version="TrEMBL_62"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6ICX" version="TrEMBL_62"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6ICY" version="TrEMBL_62"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6ID2" version="TrEMBL_62"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6ID3" version="TrEMBL_62"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6ID5" version="TrEMBL_62"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6ID8" version="TrEMBL_62"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6ID9" version="TrEMBL_62"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6IDA" version="TrEMBL_62"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6IDB" version="TrEMBL_62"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6IDZ" version="TrEMBL_62"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6UIG" version="TrEMBL_62"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="YP_009118475.1"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-61423N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="1332244">
          <names>
            <shortLabel>influenza a virus (a/shanghai/02/2013(h7n9))</shortLabel>
            <fullName>Influenza A virus (A/Shanghai/02/2013(H7N9))</fullName>
          </names>
        </organism>
        <sequence>MNTQILVFALIAIIPTNADKICLGHHAVSNGTKVNTLTERGVEVVNATETVERTNIPRICSKGKRTVDLGQCGLLGTITGPPQCDQFLEFSADLIIERREGSDVCYPGKFVNEEALRQILRESGGIDKEAMGFTYSGIRTNGATSACRRSGSSFYAEMKWLLSNTDNAAFPQMTKSYKNTRKSPALIVWGIHHSVSTAEQTKLYGSGNKLVTVGSSNYQQSFVPSPGARPQVNGLSGRIDFHWLMLNPNDTVTFSFNGAFIAPDRASFLRGKSMGIQSGVQVDANCEGDCYHSGGTIISNLPFQNIDSRAVGKCPRYVKQRSLLLATGMKNVPEIPKGRGLFGAIAGFIENGWEGLIDGWYGFRHQNAQGEGTAADYKSTQSAIDQITGKLNRLIEKTNQQFELIDNEFNEVEKQIGNVINWTRDSITEVWSYNAELLVAMENQHTIDLADSEMDKLYERVKRQLRENAEEDGTGCFEIFHKCDDDCMASIRNNTYDHSKYREEAMQNRIQIDPVKLSSGYKDVILWFSFGASCFILLAIVMGLVFICVKNGNMRCTICI</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein R4NN21 original sequence version: 15</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="3" imexId="IM-24252-1">
        <names>
          <shortLabel>ha-12</shortLabel>
        </names>
        <xref>
          <primaryRef db="dip" dbAc="MI:0465" id="DIP-198806E" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-16084250" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-24252-1" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="4">
            <interactorRef>2</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>unspecified role</shortLabel>
                  <fullName>unspecified role</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <featureList>
              <feature id="5">
                <names>
                  <shortLabel>Region 19-515</shortLabel>
                  <fullName>Region 19-515</fullName>
                </names>
                <xref>
                  <primaryRef db="intact" dbAc="MI:0469" id="EBI-16084255" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>sufficient to bind</shortLabel>
                    <fullName>sufficient binding region</fullName>
                    <alias type="synonym" typeAc="MI:1041">sufficient to bind</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0442" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608899" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <begin position="19"/>
                    <endStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
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                      </xref>
                    </endStatus>
                    <end position="515"/>
                  </featureRange>
                </featureRangeList>
              </feature>
            </featureList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="7111">
                <names>
                  <shortLabel>trini</shortLabel>
                  <fullName>Trichoplusia ni (Cabbage looper)</fullName>
                  <alias type="synonym" typeAc="MI:1041">Cabbage looper</alias>
                </names>
              </hostOrganism>
            </hostOrganismList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>direct interaction</shortLabel>
            <fullName>direct interaction</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
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          </xref>
        </interactionType>
      </interaction>
    </interactionList>
  </entry>
</entrySet>