DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins. The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins. Science (New York, N.Y.) 2014 imex curation Lu G., Middleton RE., Sun H., Naniong M., Ott CJ., Mitsiades CS., Wong KK., Bradner JE., Kaelin WG. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Lu G., Middleton RE., Sun H., Naniong M., Ott CJ., Mitsiades CS., Wong KK., Bradner JE., Kaelin WG. DIP original experiment: DIP-265023X Science (New York, N.Y.) 2014 IMEx The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins. The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins. The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins. Science (New York, N.Y.) 2014 imex curation Lu G., Middleton RE., Sun H., Naniong M., Ott CJ., Mitsiades CS., Wong KK., Bradner JE., Kaelin WG. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Lu G., Middleton RE., Sun H., Naniong M., Ott CJ., Mitsiades CS., Wong KK., Bradner JE., Kaelin WG. DIP original experiment: DIP-265013X Science (New York, N.Y.) 2014 IMEx The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins. The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins. The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins. Science (New York, N.Y.) 2014 imex curation Lu G., Middleton RE., Sun H., Naniong M., Ott CJ., Mitsiades CS., Wong KK., Bradner JE., Kaelin WG. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Lu G., Middleton RE., Sun H., Naniong M., Ott CJ., Mitsiades CS., Wong KK., Bradner JE., Kaelin WG. DIP original experiment: DIP-265022X Science (New York, N.Y.) 2014 IMEx The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins. The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins. The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins. Science (New York, N.Y.) 2014 imex curation Lu G., Middleton RE., Sun H., Naniong M., Ott CJ., Mitsiades CS., Wong KK., Bradner JE., Kaelin WG. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Lu G., Middleton RE., Sun H., Naniong M., Ott CJ., Mitsiades CS., Wong KK., Bradner JE., Kaelin WG. DIP original experiment: DIP-265014X Science (New York, N.Y.) 2014 IMEx The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins. The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins. The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins. Science (New York, N.Y.) 2014 imex curation Lu G., Middleton RE., Sun H., Naniong M., Ott CJ., Mitsiades CS., Wong KK., Bradner JE., Kaelin WG. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Lu G., Middleton RE., Sun H., Naniong M., Ott CJ., Mitsiades CS., Wong KK., Bradner JE., Kaelin WG. DIP original experiment: DIP-265020X Science (New York, N.Y.) 2014 IMEx The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins. The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins. The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins. Science (New York, N.Y.) 2014 imex curation Lu G., Middleton RE., Sun H., Naniong M., Ott CJ., Mitsiades CS., Wong KK., Bradner JE., Kaelin WG. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Lu G., Middleton RE., Sun H., Naniong M., Ott CJ., Mitsiades CS., Wong KK., Bradner JE., Kaelin WG. DIP original experiment: DIP-265024X Science (New York, N.Y.) 2014 IMEx The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins. The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins. The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins. Science (New York, N.Y.) 2014 imex curation Lu G., Middleton RE., Sun H., Naniong M., Ott CJ., Mitsiades CS., Wong KK., Bradner JE., Kaelin WG. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Lu G., Middleton RE., Sun H., Naniong M., Ott CJ., Mitsiades CS., Wong KK., Bradner JE., Kaelin WG. DIP original experiment: DIP-265018X Science (New York, N.Y.) 2014 IMEx The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins. The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins. The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins. Science (New York, N.Y.) 2014 imex curation Lu G., Middleton RE., Sun H., Naniong M., Ott CJ., Mitsiades CS., Wong KK., Bradner JE., Kaelin WG. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Lu G., Middleton RE., Sun H., Naniong M., Ott CJ., Mitsiades CS., Wong KK., Bradner JE., Kaelin WG. DIP original experiment: DIP-265017X Science (New York, N.Y.) 2014 IMEx The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins. The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins. The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins. Science (New York, N.Y.) 2014 imex curation Lu G., Middleton RE., Sun H., Naniong M., Ott CJ., Mitsiades CS., Wong KK., Bradner JE., Kaelin WG. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Lu G., Middleton RE., Sun H., Naniong M., Ott CJ., Mitsiades CS., Wong KK., Bradner JE., Kaelin WG. DIP original experiment: DIP-265021X Science (New York, N.Y.) 2014 IMEx The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins. The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins. The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins. Science (New York, N.Y.) 2014 imex curation Lu G., Middleton RE., Sun H., Naniong M., Ott CJ., Mitsiades CS., Wong KK., Bradner JE., Kaelin WG. Only protein-protein interactions human Homo sapiens Human pull down pull down anti tag western anti tag western blot anti tag western Lu G., Middleton RE., Sun H., Naniong M., Ott CJ., Mitsiades CS., Wong KK., Bradner JE., Kaelin WG. DIP original experiment: DIP-265015X Science (New York, N.Y.) 2014 IMEx The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins. The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins. The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins. Science (New York, N.Y.) 2014 imex curation Lu G., Middleton RE., Sun H., Naniong M., Ott CJ., Mitsiades CS., Wong KK., Bradner JE., Kaelin WG. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Lu G., Middleton RE., Sun H., Naniong M., Ott CJ., Mitsiades CS., Wong KK., Bradner JE., Kaelin WG. DIP original experiment: DIP-265019X Science (New York, N.Y.) 2014 IMEx The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins. The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins. The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins. Science (New York, N.Y.) 2014 imex curation Lu G., Middleton RE., Sun H., Naniong M., Ott CJ., Mitsiades CS., Wong KK., Bradner JE., Kaelin WG. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Lu G., Middleton RE., Sun H., Naniong M., Ott CJ., Mitsiades CS., Wong KK., Bradner JE., Kaelin WG. DIP original experiment: DIP-265016X Science (New York, N.Y.) 2014 IMEx The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins. q13422-7 DNA-binding protein Ikaros IKZF1 IK1 IKAROS Ikaros family zinc finger protein 1 LYF1 Lymphoid transcription factor LyF-1 ZNFN1A1 protein protein human Homo sapiens Human MDADEGQDMSQVSGKESPPVSDTPDEGDEPMPIPEDLSTTSGGQQSSKSDRVVASNVKVETQSDEENGRACEMNGEECAEDLRMLDASGEKMNGSHRDQGSSALSGVGGIRLPNGKLKCDICGIICIGPNVLMVHKRSHTGERPFQCNQCGASFTQKGNLLRHIKLHSGEKPFKCHLCNYACRRRDALTGHLRTHSVIKEETNHSEMAEDLCKIGSERSLVLDRLASNVAKRKSSMPQKFLGDKGLSDTPYDSSASYEKENEMMKSHVMDQAINNAINYLGAESLRPLVQTPPGGSEVVPVISPMYQLHKPLAEGTPRSNHSAQDSAVENLLLLSKAKLVPSEREASPSNSCQDSTDTESNNEEQRSGLIYLTNHIAPHARNGLSLKEEHRAYDLLRAASENSQDALRVVSTSGEQMKVYKCEHCRVLFLDHVMYTIHMGCHGFRDPFECNMCGYHSQDRYEFSSHITRGEHRFHMS B19FE76450EA40E4 crbn_human Protein cereblon CRBN AD-006 protein protein human Homo sapiens Human MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL DIP protein Q96SW2 original sequence version: 125 DIP protein Q96SW2 original sequence version: 124 DIP protein Q96SW2 original sequence version: 113 DIP protein Q96SW2-1 original sequence version: 107 DIP protein Q96SW2 original sequence version: 117 90DF77D98A8BEAA8 ubiq_human UBIQ_HUMAN protein protein human Homo sapiens Human MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG q13422-1 DNA-binding protein Ikaros IKZF1 IK1 IKAROS LYF1 ZNFN1A1 Ikaros family zinc finger protein 1 Lymphoid transcription factor LyF-1 protein protein human Homo sapiens Human MDADEGQDMSQVSGKESPPVSDTPDEGDEPMPIPEDLSTTSGGQQSSKSDRVVASNVKVETQSDEENGRACEMNGEECAEDLRMLDASGEKMNGSHRDQGSSALSGVGGIRLPNGKLKCDICGIICIGPNVLMVHKRSHTGERPFQCNQCGASFTQKGNLLRHIKLHSGEKPFKCHLCNYACRRRDALTGHLRTHSVGKPHKCGYCGRSYKQRSSLEEHKERCHNYLESMGLPGTLYPVIKEETNHSEMAEDLCKIGSERSLVLDRLASNVAKRKSSMPQKFLGDKGLSDTPYDSSASYEKENEMMKSHVMDQAINNAINYLGAESLRPLVQTPPGGSEVVPVISPMYQLHKPLAEGTPRSNHSAQDSAVENLLLLSKAKLVPSEREASPSNSCQDSTDTESNNEEQRSGLIYLTNHIAPHARNGLSLKEEHRAYDLLRAASENSQDALRVVSTSGEQMKVYKCEHCRVLFLDHVMYTIHMGCHGFRDPFECNMCGYHSQDRYEFSSHITRGEHRFHMS DIP protein Q13422-1 original sequence version: 144 cul4a_human Cullin-4A CUL4A protein protein human Homo sapiens Human MADEAPRKGSFSALVGRTNGLTKPAALAAAPAKPGGAGGSKKLVIKNFRDRPRLPDNYTQDTWRKLHEAVRAVQSSTSIRYNLEELYQAVENLCSHKVSPMLYKQLRQACEDHVQAQILPFREDSLDSVLFLKKINTCWQDHCRQMIMIRSIFLFLDRTYVLQNSTLPSIWDMGLELFRTHIISDKMVQSKTIDGILLLIERERSGEAVDRSLLRSLLGMLSDLQVYKDSFELKFLEETNCLYAAEGQRLMQEREVPEYLNHVSKRLEEEGDRVITYLDHSTQKPLIACVEKQLLGEHLTAILQKGLDHLLDENRVPDLAQMYQLFSRVRGGQQALLQHWSEYIKTFGTAIVINPEKDKDMVQDLLDFKDKVDHVIEVCFQKNERFVNLMKESFETFINKRPNKPAELIAKHVDSKLRAGNKEATDEELERTLDKIMILFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMVHFKQHMQNQSDSGPIDLTVNILTMGYWPTYTPMEVHLTPEMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEEIKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVRIMKMRKTLGHNLLVSELYNQLKFPVKPGDLKKRIESLIDRDYMERDKDNPNQYHYVA DIP protein Q13619 original sequence version: 136 DIP protein Q13619 original sequence version: 131 DIP protein Q13619 original sequence version: 129 DIP protein Q13619 original sequence version: 87 DIP protein Q13619 original sequence version: 104 DIP protein Q13619 original sequence version: 151 DIP protein Q13619 original sequence version: 111 DIP protein Q13619 original sequence version: 140 3C4C6A1BBD94D51B ddb1_human DNA damage-binding protein 1 DDB1 Damage-specific DNA-binding protein 1 UV-damaged DNA-binding factor DDB p127 subunit DNA damage-binding protein a UV-damaged DNA-binding protein 1 Xeroderma pigmentosum group E-complementing protein XPE-binding factor HBV X-associated protein 1 XAP1 protein protein human Homo sapiens Human MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH DIP protein Q16531 original sequence version: 145 DIP protein Q16531 original sequence version: 140 DIP protein Q16531 original sequence version: 99 DIP protein Q16531 original sequence version: 93 DIP protein Q16531 original sequence version: 116 DIP protein Q16531 original sequence version: 111 DIP protein Q16531-1 original sequence version: 163 DIP protein Q16531 original sequence version: 162 DIP protein Q16531 original sequence version: 113 DIP protein Q16531 original sequence version: 132 DIP protein Q16531 original sequence version: 139 DIP protein Q16531 original sequence version: 151 DIP protein Q16531-1 original sequence version: 144 DIP protein Q16531 original sequence version: 155 74D082023E3D846D ikzf3_human Zinc finger protein Aiolos ZNFN1A3 Ikaros family zinc finger protein 3 IKZF3 protein protein human Homo sapiens Human MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDDSMKVKDEYSERDENVLKSEPMGNAEEPEIPYSYSREYNEYENIKLERHVVSFDSSRPTSGKMNCDVCGLSCISFNVLMVHKRSHTGERPFQCNQCGASFTQKGNLLRHIKLHTGEKPFKCHLCNYACQRRDALTGHLRTHSVEKPYKCEFCGRSYKQRSSLEEHKERCRTFLQSTDPGDTASAEARHIKAEMGSERALVLDRLASNVAKRKSSMPQKFIGEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNAISYLGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIYQQNHMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDPFECNMCGYRSHDRYEFSSHIARGEHRALLK DIP protein Q9UKT9 original sequence version: 126 D1BB4A0A9A71B81A q96sw2-2 Protein cereblon CRBN AD-006 protein protein human Homo sapiens Human MAGEGDQQDAAHNMGNHLPLLPESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL No experimental confirmation available. 28B44733BBB461C1 ikzf1_human DNA-binding protein Ikaros Ikaros family zinc finger protein 1 Lymphoid transcription factor LyF-1 IKZF1 IK1 IKAROS LYF1 ZNFN1A1 protein protein human Homo sapiens Human MDADEGQDMSQVSGKESPPVSDTPDEGDEPMPIPEDLSTTSGGQQSSKSDRVVASNVKVETQSDEENGRACEMNGEECAEDLRMLDASGEKMNGSHRDQGSSALSGVGGIRLPNGKLKCDICGIICIGPNVLMVHKRSHTGERPFQCNQCGASFTQKGNLLRHIKLHSGEKPFKCHLCNYACRRRDALTGHLRTHSVGKPHKCGYCGRSYKQRSSLEEHKERCHNYLESMGLPGTLYPVIKEETNHSEMAEDLCKIGSERSLVLDRLASNVAKRKSSMPQKFLGDKGLSDTPYDSSASYEKENEMMKSHVMDQAINNAINYLGAESLRPLVQTPPGGSEVVPVISPMYQLHKPLAEGTPRSNHSAQDSAVENLLLLSKAKLVPSEREASPSNSCQDSTDTESNNEEQRSGLIYLTNHIAPHARNGLSLKEEHRAYDLLRAASENSQDALRVVSTSGEQMKVYKCEHCRVLFLDHVMYTIHMGCHGFRDPFECNMCGYHSQDRYEFSSHITRGEHRFHMS DIP protein Q13422 original sequence version: 144 7B0129C4E3FE41A8 ub-crbn-1 10 15 unspecified role unspecified role bait bait His-tag His-tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal human Homo sapiens Human 20 unspecified role unspecified role prey prey Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human Homo sapiens Human 13 unspecified role unspecified role prey prey V5-tag V5-tag v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human Homo sapiens Human association association crbn-ddb1-1 5 19 unspecified role unspecified role prey prey HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range human Homo sapiens Human 18 unspecified role unspecified role prey prey human Homo sapiens Human 20 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human Homo sapiens Human association association ikzf1-crbn-1 2 13 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human Homo sapiens Human 14 unspecified role unspecified role prey prey human Homo sapiens Human physical association physical association crbn-ddb1-2 3 19 unspecified role unspecified role prey prey human Homo sapiens Human 21 unspecified role unspecified role prey prey human Homo sapiens Human 18 unspecified role unspecified role prey prey HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human 20 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human Homo sapiens Human association association ikzf3-crbn-1 1 19 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged c-term range C-terminal range c-term range c-term range C-terminal range c-term range Q9UKT9:p.Gln147His Q147H mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain Q H This feature has been corrected as a result of our quality control procedures. The original label was 'Q147H'. Wed May 02 18:19:17 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'gln147his' Tue Jun 30 17:02:44 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Gln147His' human Homo sapiens Human 14 unspecified role unspecified role prey prey human Homo sapiens Human physical association physical association crbn-cul4a-1 7 17 unspecified role unspecified role prey prey human Homo sapiens Human 18 unspecified role unspecified role prey prey human Homo sapiens Human 20 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human Homo sapiens Human association association ikzf1-crbn-2 4 20 unspecified role unspecified role prey prey Q96SW2-2:p.[Tyr383Ala;Trp385Ala] Y383A/W385A mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain W A certain certain sequence position certain certain certain sequence position certain Y A This feature has been corrected as a result of our quality control procedures. The original label was 'Y383A/W385A'. Wed May 02 15:04:58 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'tyr383ala,trp385ala' Tue Jun 30 20:02:55 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Tyr383Ala;Trp385Ala]' HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human Homo sapiens Human 13 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human Homo sapiens Human physical association physical association crbn-cul4a-2 8 19 unspecified role unspecified role prey prey HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range human Homo sapiens Human 17 unspecified role unspecified role prey prey human Homo sapiens Human 18 unspecified role unspecified role prey prey human Homo sapiens Human 20 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human Homo sapiens Human association association crbn-ddb1-3 9 18 unspecified role unspecified role prey prey HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human 20 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human Homo sapiens Human physical association physical association ikzf1-crbn-3 6 16 unspecified role unspecified role bait bait Q13422-1:p.Gln146His Q146H mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain Q H This feature has been corrected as a result of our quality control procedures. The original label was 'Q146H'. Wed May 02 14:25:50 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'gln146his' Tue Jun 30 17:50:09 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Gln146His' Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human Homo sapiens Human 14 unspecified role unspecified role prey prey human Homo sapiens Human physical association physical association crbn-cul4a-3 12 17 unspecified role unspecified role prey prey human Homo sapiens Human 18 unspecified role unspecified role prey prey human Homo sapiens Human 20 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human Homo sapiens Human 13 unspecified role unspecified role prey prey HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human Homo sapiens Human association association crbn-ddb1-4 11 18 unspecified role unspecified role prey prey human Homo sapiens Human 20 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human Homo sapiens Human physical association physical association