DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Structural basis of a rationally rewired protein-protein interface critical to bacterial signaling. Structural basis of a rationally rewired protein-protein interface critical to bacterial signaling. Structure (London, England : 1993) 2013 imex curation Podgornaia AI., Casino P., Marina A., Laub MT. Only protein-protein interactions in vitro In vitro x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Podgornaia AI., Casino P., Marina A., Laub MT. DIP original experiment: DIP-255804X Structure (London, England : 1993) 2013 IMEx Structural basis of a rationally rewired protein-protein interface critical to bacterial signaling. Structural basis of a rationally rewired protein-protein interface critical to bacterial signaling. Structural basis of a rationally rewired protein-protein interface critical to bacterial signaling. Structure (London, England : 1993) 2013 imex curation Podgornaia AI., Casino P., Marina A., Laub MT. Only protein-protein interactions in vitro In vitro phosphotransferase phosphotransferase assay phosphotransferase weight autoradiogra molecular weight estimation by autoradiography weight autoradiogra Podgornaia AI., Casino P., Marina A., Laub MT. DIP original experiment: DIP-255800X Structure (London, England : 1993) 2013 IMEx Structural basis of a rationally rewired protein-protein interface critical to bacterial signaling. Structural basis of a rationally rewired protein-protein interface critical to bacterial signaling. Structural basis of a rationally rewired protein-protein interface critical to bacterial signaling. Structure (London, England : 1993) 2013 imex curation Podgornaia AI., Casino P., Marina A., Laub MT. Only protein-protein interactions in vitro In vitro protein kinase assay protein kinase assay weight autoradiogra molecular weight estimation by autoradiography weight autoradiogra Podgornaia AI., Casino P., Marina A., Laub MT. DIP original experiment: DIP-255801X Structure (London, England : 1993) 2013 IMEx Structural basis of a rationally rewired protein-protein interface critical to bacterial signaling. Structural basis of a rationally rewired protein-protein interface critical to bacterial signaling. Structural basis of a rationally rewired protein-protein interface critical to bacterial signaling. Structure (London, England : 1993) 2013 imex curation Podgornaia AI., Casino P., Marina A., Laub MT. Only protein-protein interactions in vitro In vitro protein kinase assay protein kinase assay weight autoradiogra molecular weight estimation by autoradiography weight autoradiogra Podgornaia AI., Casino P., Marina A., Laub MT. DIP original experiment: DIP-255803X Structure (London, England : 1993) 2013 IMEx Structural basis of a rationally rewired protein-protein interface critical to bacterial signaling. Structural basis of a rationally rewired protein-protein interface critical to bacterial signaling. Structural basis of a rationally rewired protein-protein interface critical to bacterial signaling. Structure (London, England : 1993) 2013 imex curation Podgornaia AI., Casino P., Marina A., Laub MT. Only protein-protein interactions in vitro In vitro phosphotransferase phosphotransferase assay phosphotransferase weight autoradiogra molecular weight estimation by autoradiography weight autoradiogra Podgornaia AI., Casino P., Marina A., Laub MT. DIP original experiment: DIP-255802X Structure (London, England : 1993) 2013 IMEx Structural basis of a rationally rewired protein-protein interface critical to bacterial signaling. r4p0t2_thema Tmari_1263 protein protein thema Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) MIELEDLDHIREAIVILKGLEVEGANKPGEKLGFKKGKNLMSIFTCKEMDRFIRDVQERKNFSLETNAYFFELHSKRFVSLRYLPKKSLLFVNDLTEERTLSEAKLDFVTAVSHELFTPLSASKANVFLLKDIENDPEKLEILGKVERSLDRMETIIRQLKVLTMIQLRLYELKMEHIPVEEVVHMVLEELREKIESKKIKVNVFVDVETIETDRFVFHTILKNLVSNAVKYSYPDSVVEISITGERLSVKDQGIGIKEEEKSRIFERFYRGSEALKMAPGSGLGLSIVKHLCDTIGYRLEVNSQWLVGSEFIVHFK DIP protein R4P0T2 original sequence version: 1 q9wzv7_thema TM_0853 protein protein thema Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) MEEIKEQNNRLFLLLSIMIMEFSNAKTESDILQGLLNLVRKVVDIKEVVLVDENKRKIWGRDIDIKRFEEFIDWSIRQSNPVFVEDELGYVGIVPVVKQDRMFGSLIVLLNHQPSMEETEIFKVLSFLSAVVLENIKLYRELEETYNYVNVILNGLPEGIFVYSNGEIKFQNEKFKEENFPDEVLRKAISLSEEAISLRTQRVGEVISGEEFFSITSIPLILGSEVQALTIVENVTESKELERLKRIDRMKTEFIANISHELRTPLTAIKAYAETIYNSLGELDLSTLKEFLEVIIDQSNHLENLLNELLDFSRLERKSLQINREKVDLCDLVESAVNAIKEFASSHNVNVLFESNVPCPVEAYIDPTRIRQVLLNLLNNGVKYSKKDAPDKYVKVILDEKDGGVLIIVEDNGIGIPDHAKDRIFEQFYRVDSSLTYEVPGTGLGLAITKEIVELHGGRIWVESEVGKGSRFFVWIPKDRAGEDNRQDN DIP protein Q9WZV7 original sequence version: 94 40F19F843A4EDDB4 q9x0y6_thema TM_1259 protein protein thema Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) MLRVGVKVLIAEDDEDIRSVLKRYLETEGYECDEAESLFDLKKKLSEGTYNVLLLDLMFPDGVAMDEIPEMKVSHPEMAIIIISARDRDMDRIFGIELGADDYVTKPFNPREVLARVKAVLRRMGKEQKVLRFGRLEIFPEDYIVRYDGKNVEMTAKEFELLKLLATTPNKVFSREEILNRVWGDDYVSDRVVDVHISAIRSKIGKGWIKTVRGLGYKFSTRGDEGDRA DIP protein Q9X0Y6 original sequence version: 74 q9wyt9_thema TM_0468 protein protein thema Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) MSKKVLLVDDSAVLRKIVSFNLKKEGYEVIEAENGQIALEKLSEFTPDLIVLDIMMPVMDGFTVLKKLQEKEEWKRIPVIVLTAKGGEEDESLALSLGARKVMRKPFSPSQFIEEVKHLLNE DIP protein Q9WYT9 original sequence version: 86 D946EB06B5F279E0 q9wyt9_thema-q9wzv7_thema-1 2 9 phosphate acceptor phosphate acceptor unspecified role unspecified role ecolx Escherichia coli 7 phosphate donor phosphate donor unspecified role unspecified role Region 232-489 Region 232-489 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli phosphotransfer phosphotransfer reaction phosphotransfer r4p0t2_thema-1 4 6 putative self putative self unspecified role unspecified role in vitro In vitro phosphorylation phosphorylation reaction phosphorylation true q9wyt9_thema-q9wzv7_thema-2 1 9 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli 7 unspecified role unspecified role unspecified role unspecified role Region 232-489 Region 232-489 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction q9wzv7_thema-1 3 7 putative self putative self unspecified role unspecified role Region 232-489 Region 232-489 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli phosphorylation phosphorylation reaction phosphorylation true q9x0y6_thema-r4p0t2_thema-1 5 8 phosphate acceptor phosphate acceptor unspecified role unspecified role ecolx Escherichia coli 6 phosphate donor phosphate donor unspecified role unspecified role in vitro In vitro phosphotransfer phosphotransfer reaction phosphotransfer