DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu A role for the Perlman syndrome exonuclease Dis3l2 in the Lin28-let-7 pathway. A role for the Perlman syndrome exonuclease Dis3l2 in the Lin28-let-7 pathway. Nature 2013 imex curation Chang HM., Triboulet R., Thornton JE., Gregory RI. Only protein-protein interactions mouse Mus musculus Mouse anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Chang HM., Triboulet R., Thornton JE., Gregory RI. DIP original experiment: DIP-252870X Nature 2013 IMEx A role for the Perlman syndrome exonuclease Dis3l2 in the Lin28-let-7 pathway. A role for the Perlman syndrome exonuclease Dis3l2 in the Lin28-let-7 pathway. A role for the Perlman syndrome exonuclease Dis3l2 in the Lin28-let-7 pathway. Nature 2013 imex curation Chang HM., Triboulet R., Thornton JE., Gregory RI. Only protein-protein interactions mouse Mus musculus Mouse anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Chang HM., Triboulet R., Thornton JE., Gregory RI. DIP original experiment: DIP-252871X Nature 2013 IMEx A role for the Perlman syndrome exonuclease Dis3l2 in the Lin28-let-7 pathway. ln28a_mouse Protein lin-28 homolog A Lin28a Lin28 Testis-expressed protein 17 Tex17 protein protein mouse Mus musculus Mouse MGSVSNQQFAGGCAKAAEKAPEEAPPDAARAADEPQLLHGAGICKWFNVRMGFGFLSMTARAGVALDPPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKKSAKGLESIRVTGPGGVFCIGSERRPKGKNMQKRRSKGDRCYNCGGLDHHAKECKLPPQPKKCHFCQSINHMVASCPLKAQQGPSSQGKPAYFREEEEEIHSPALLPEAQN DIP protein Q8K3Y3 original sequence version: 64 DIP protein Q8K3Y3 original sequence version: 88 4BD14DCAF13CD659 tut7_mouse Terminal uridylyltransferase 7 Tut7 Kiaa1711 Zcchc6 Zinc finger CCHC domain-containing protein 6 protein protein mouse Mus musculus Mouse MGDTAKPYFVKRTKDRGIIDDDDFRRGHPQQDYLIMDDYAKGHSSKMEKGLPKKKISPGNYGNTPRKGLYGVSSNPYAFKNPIYSQPAWMNDNHKDQNKKWLSDELAGNADSWREFKPGPRIPVISRSRKESFQESDDAYRWQEGRGCRAVRRLFQKDLSSLEAMSEMEAGSPENKKQRSRPRKPRRTRTEDSEQDGDLDGPVIDESVLSTKELLGLQQAEERLKRDCIDRLKRRPRNCPTAKYTCKLCDALIDSIPFAHKHIKEKRHKKNLKEKQEEELLTTLPPPAPSQIHAVGSAIDRVVQEFGLHSENLDQRLEIKRVMESVFRHKLPDCSLRLYGSSCSRLGFRDSDVNIDVQFPAVMSQPDVLLLVQECLKNSDSFIDVDADFHARVPVVVCRDKQSGLLCKVSAGNENAWLTTKHLTALGKLEPRLVPLVIAFRYWAKLCSIDRPEEGGLPPYVFALMAVFFLQQRKEPLLPVYLGSWIEEFSLNKLGNFSLKDVEKDSVVWEYTDNSTGDTSSAKEEAPKETAAKKGQVPLTFNIKHQPSVPVGQLWVELLRFYALEFNLADLVISIRVKELISRESKDWPKKRIAIEDPYSVKRNVARTLNNQPVFEYILHCLRTTYKYFALPHKVTKPNLTKPPSPVTCVSDPYREAKNGGPEPQATNIDKLGNAAVAQDPGVQTSGDCRAQLVTLKNTTEEVGSPAKEKTGGVHIPAHQESSGCVQAEVSCEGLEDATAELPETGSDNEEVRRKTKHPLSTDDQGLSSSKHPELQNCGSLCGLQADNTLELVAEECNSCASLDNKAEVNEERIEGAEELEEAAALSCFSPSVQSRTSAAMHFDDEEEEEEEEEEEEPRLSINLTEDEEGVANEHQVDSRYAGSGEEDALSEEDDLAEPAKGEDTGECGENVGGTLLIDLNRITLKEESFPEEDLPGDQSEFFYEFRKLTFTKGKSPTVVCSLCKREGHLKKDCPEDFKRVQLEPLPPLTPKFSNILDQVCVQCYKDFSPTIVEDQAREHIRQNLESFIKQDFPGTKLSLFGSSKNGFGFKQSDLDVCMTINGHETAEGLDCVRTIEELARVLRKHSGLRNILPITTAKVPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAYSAIDPRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRSPPVIPVLQEIYKGEKKPEILVDGWNIYFFDQINELPTCWPEYGKNTEPVGQLWLGLLRFYTEEFDFKEHVISIRRKSLLTTFKKQWTSKYIVIEDPFDLNHNLGAGLSRKMTNFIMKAFINGRRVFGIPVKGFPKDNPSKLAYFFDPDVLTEGELAPNDRCCRICGKIGHFMKDCPMRRKVRRRRDQEDTPNQRYSESKEKRSKEDKEIQNKYTEKEVSTKEDKLTPCAAAKAKPVRAAVDLGREKLLRTPTEKWKRQDDRDSREKRCFICGREGHIKKECPQFKGSPGSLSSKYMTQGRASVKRTQQES DIP protein Q5BLK4 original sequence version: 72 mint C574FCAC3781B3CC di3l2_mouse DIS3-like exonuclease 2 Dis3l2 protein protein mouse Mus musculus Mouse MNHPDYKLNLRSPGTPRGVSSVVGPSAVGASPGDKKSKNKSMRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPKKFHEAFIPSPDGDRDIFIDGVVARNRALNGDLVVVKLLPEDQWKAVKPESNDKEIEATYEADIPEEGCGHHPLQQSRKGWSGPDVIIEAQFDDSDSEDRHGNTSGLVDGVKKLSISTPDRGKEDSSTPVMKDENTPIPQDTRGLSEKSLQKSAKVVYILEKKHSRAATGILKLLADKNSDLFKKYALFSPSDHRVPRIYVPLKDCPQDFMTRPKDFANTLFICRIIDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFSSEVLECLPQSLPWTIPPDEVGKRRDLRKDCIFTIDPSTARDLDDALACRRLTDGTFEVGVHIADVSYFVPEGSSLDKVAAERATSVYLVQKVVPMLPRLLCEELCSLNPMTDKLTFSVIWKLTPEGKILEEWFGRTIIRSCTKLSYDHAQSMIENPTEKIPEEELPPISPEHSVEEVHQAVLNLHSIAKQLRRQRFVDGALRLDQLKLAFTLDHETGLPQGCHIYEYRDSNKLVEEFMLLANMAVAHKIFRTFPEQALLRRHPPPQTKMLSDLVEFCDQMGLPMDVSSAGALNKSLTKTFGDDKYSLARKEVLTNMYSRPMQMALYFCSGMLQDQEQFRHYALNVPLYTHFTSPIRRFADVIVHRLLAAALGYSEQPDVEPDTLQKQADHCNDRRMASKRVQELSIGLFFAVLVKESGPLESEAMVMGVLNQAFDVLVLRFGVQKRIYCNALALRSYSFQKVGKKPELTLVWEPDDLEEEPTQQVITIFSLVDVVLQAEATALKYSAILKRPGLEKASDEEPED DIP protein Q8CI75 original sequence version: 74 tut4_mouse Terminal uridylyltransferase 4 Zcchc11 Tut4 Kiaa0191 Zinc finger CCHC domain-containing protein 11 protein protein mouse Mus musculus Mouse MEEPKTSKNENHEPKKNIICEESKAVKIISNQTLKPRNDKSEIGTSSLNRNSSKKTKQNDICIEKTEAKSCKVNAASVPGPKDLGLVHRDQSHCKMKKLPNSPMKAQKGSSQTKLEKTPSLQTKAEKVPKSPNLPVKAEKAPCTTAEATTEKALNSQRKEENTPTSQMKLQKTPRSPLEPENVPSLLLKENVKQTESQQTGKKLTSSFVSMDKRKSEALQGEKSALENSSLSQKQQTQTDNIADSDDSASGIEDTADDLSKMKSEESNKENSSEMDYLENATVIDESALTPEQRLGLKQAEERLERDHIFRLEKRSPEYTNCRYLCKLCLIHIENIQGAHKHIKEKRHKKNILEKQEESELRSLPSPSSAHLAALSVAVVELAKEQGITDDDLRIRQDIVEEMSKVIMTFLPECSLRLYGSSLTKFALKSSDVNIDIKFPPKMNHPDLLIQVLGILKKSALYIDVESDFHAKVPVVVCKDRKSALLCRVSAGNDMACLTTDLLAALGKVEPVFTPLVLAFRYWAKLCYIDSQTDGGIPSYCFALMVMFFLQQRKPPLLPCLLGSWIEGFDPKRMDDFQLKGIVEEKFVKWEYNSSSATEKNLIADENKAKADEPKDDTKKTETDNQSNAAKAKHGKSPLTLEAPNQVPLGQLWLELLKFYTLDFALEEYVICVRIQDILTRENKNWPKRRIAIEDPFSVKRNVARSLNSQLVYEYVVERFRAAYRYFACPQKKGGNKSTMDPKKKEKGKLSSKKPVKSDCSATNCCILGESAEKIHMERGQPAKHDETEFTSQRCIVDNDSLLVNELGLANHGQDSSSLSTASGGSDLKQKSAEKQGDLTPSETSLKKELSQCICIGTPDGAESAGTDCRSNLEMDSSHQIVCNNVSATSCNCKATEVTSDLVDEDNLPSQELYYVFDKFILTSGKPPTIVCSICKKDGHSKNDCPEDFRKIDLKPLPPMTNRFREILDLVCKRCFDELSPPCSEQHNREQILIGLEKFIQKEYDEKARLCLFGSSKNGFGFRDSDLDICMTLEGHENAEKLNCKEIIENLAKILKRHPGLRNILPITTAKVPIVKFEHRRSGLEGDISLYNTLAQHNTRMLATYAAIDPRVQYLGYTMKVFAKRCDIGDASRGSLSSYAYILMVLYFLQQRKPPVIPVLQEIFDGKQIPQRMVDGWNAFFFDKTEELKKRLPSLGKNTESLGELWLGLLRFYTEEFDFKEYVISIRQKKLLTTFEKQWTSKCIAIEDPFDLNHNLGAGVSRKMTNFIMKAFINGRKLFGTPFYPLIGREAEYFFDSRVLTDGELAPNDRCCRVCGKIGHYMKDCPKRKRLKKKDSEEEKEGNEEEKDSRDLLDSRDLRCFICGDAGHVRRECPEVKMARQRNSSVAAAQLVRNLVNAQQVAGSAQQQSDQSIRTRQSSECSDSPSYSPQPQPFPQNSPQPSALPPPPSQPGSQPKLGPPQQGGQPPHQVQMPLYNFPQSPPAHYSPMHSMGLLPMHPLQIPAPSWPIHGPMLHSAPGSTPSNIGLNDPSIIFAQPAARPMAIPSPSHDGHWPRTVAPNSLVNNGAVGNSEPRFRGLNPPIPWEHAPRHFPLVPASWPYGLHQNFMHQGNPRFQPKPFYAQADRCATRRCRERCPHPPRGNVSE DIP protein B2RX14 original sequence version: 20 DIP protein B2RX14 original sequence version: 44 lin28a-dis3l2-1 1 4 unspecified role unspecified role prey prey mouse Mus musculus Mouse 5 unspecified role unspecified role prey prey mouse Mus musculus Mouse 6 unspecified role unspecified role prey prey mouse Mus musculus Mouse 3 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range mouse Mus musculus Mouse association association lin28a-dis3l2-2 2 5 unspecified role unspecified role prey prey mouse Mus musculus Mouse 3 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range Q8K3Y3:p.Trp46Ala W46A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength certain certain sequence position certain certain certain sequence position certain W A This feature has been corrected as a result of our quality control procedures. The original label was 'W46A'. Wed May 02 19:39:05 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'trp46ala' Tue Jun 30 18:29:20 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Trp46Ala' mouse Mus musculus Mouse physical association physical association