DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Structural basis for kinesin-1:cargo recognition. Structural basis for kinesin-1:cargo recognition. Science (New York, N.Y.) 2013 imex curation Pernigo S., Lamprecht A., Steiner RA., Dodding MP. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Pernigo S., Lamprecht A., Steiner RA., Dodding MP. DIP original experiment: DIP-266829X Science (New York, N.Y.) 2013 IMEx Structural basis for kinesin-1:cargo recognition. Structural basis for kinesin-1:cargo recognition. Structural basis for kinesin-1:cargo recognition. Science (New York, N.Y.) 2013 imex curation Pernigo S., Lamprecht A., Steiner RA., Dodding MP. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Pernigo S., Lamprecht A., Steiner RA., Dodding MP. DIP original experiment: DIP-266828X Science (New York, N.Y.) 2013 IMEx Structural basis for kinesin-1:cargo recognition. Structural basis for kinesin-1:cargo recognition. Structural basis for kinesin-1:cargo recognition. Science (New York, N.Y.) 2013 imex curation Pernigo S., Lamprecht A., Steiner RA., Dodding MP. Only protein-protein interactions in vitro In vitro fps fluorescence polarization spectroscopy Fluorescence anisotropy FPS FPS Fluorescence anisotropy fps predetermined predetermined participant predetermined Pernigo S., Lamprecht A., Steiner RA., Dodding MP. DIP original experiment: DIP-266831X Science (New York, N.Y.) 2013 IMEx Structural basis for kinesin-1:cargo recognition. Structural basis for kinesin-1:cargo recognition. Structural basis for kinesin-1:cargo recognition. Science (New York, N.Y.) 2013 imex curation Pernigo S., Lamprecht A., Steiner RA., Dodding MP. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Pernigo S., Lamprecht A., Steiner RA., Dodding MP. DIP original experiment: DIP-266830X Science (New York, N.Y.) 2013 IMEx Structural basis for kinesin-1:cargo recognition. Structural basis for kinesin-1:cargo recognition. Structural basis for kinesin-1:cargo recognition. Science (New York, N.Y.) 2013 imex curation Pernigo S., Lamprecht A., Steiner RA., Dodding MP. Only protein-protein interactions in vitro In vitro fps fluorescence polarization spectroscopy Fluorescence anisotropy FPS FPS Fluorescence anisotropy fps predetermined predetermined participant predetermined Pernigo S., Lamprecht A., Steiner RA., Dodding MP. DIP original experiment: DIP-266832X Science (New York, N.Y.) 2013 IMEx Structural basis for kinesin-1:cargo recognition. Structural basis for kinesin-1:cargo recognition. Structural basis for kinesin-1:cargo recognition. Science (New York, N.Y.) 2013 imex curation Pernigo S., Lamprecht A., Steiner RA., Dodding MP. Only protein-protein interactions in vitro In vitro fps fluorescence polarization spectroscopy Fluorescence anisotropy FPS FPS Fluorescence anisotropy fps predetermined predetermined participant predetermined Pernigo S., Lamprecht A., Steiner RA., Dodding MP. DIP original experiment: DIP-266833X Science (New York, N.Y.) 2013 IMEx Structural basis for kinesin-1:cargo recognition. o94985-2 Calsyntenin-1 CLSTN1 CS1 KIAA0911 Alcadein-alpha Alzheimer-related cadherin-like protein Non-classical cadherin XB31alpha Alcalpha1 protein protein human Homo sapiens Human MLRRPAPALAPAARLLLAGLLCGGGVWAARVNKHKPWLEPTYHGIVTENDNTVLLDPPLIALDKDAPLRFAGEICGFKIHGQNVPFDAVVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEKSYKATVIEGKQYDSILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKDGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISIKPTCTPGWQGWNNRIEYEPGTGALAVFPNIHLETCDEPVASVQATVELETSHIGKGCDRDTYSEKSLHRLCGAAAGTAELLPSPSGSLNWTMGLPTDNGHDSDQVFEFNGTQAVRIPDGVVSVSPKEPFTISVWMRHGPFGRKKETILCSSDKTDMNRHHYSLYVHGCRLIFLFRQDPSEEKKYRPAEFHWKLNQVCDEEWHHYVLNVEFPSVTLYVDGTSHEPFSVTEDYPLHPSKIETQLVVGACWQEFSGVENDNETEPVTVASAGGDLHMTQFFRGNLAGLTLRSGKLADKKVIDCLYTCKEGLDLQVLEDSGRGVQIQAHPSQLVLTLEGEDLGELDKAMQHISYLNSRQFPTPGIRRLKITSTIKCFNEATCISVPPVDGYVMVLQPEEPKISLSGVHHFARAASEFESSEGVFLFPELRIISTITREVEPEGDGAEDPTVQESLVSEEIVHDLDTCEVTVEGEELNHEQESLEVDMARLQQKGIEVSSSELGMTFTGVDTMASYEEVLHLLRYRNWHARSLLDRKFKLICSELNGRYISNEFKVEVNVIHTANPMEHANHMAAQPQFVHPEHRSFVDLSGHNLANPHPFAVVPSTATVVIVVCVSFLVFMIILGVFRIRAAHRRTMRDQDTGKENEMDWDDSALTITVNPMETYEDQHSSEEEEEEEEEEESEDGEEEDDITSAESESSEEEEGEQGDPQNATRQQQLEWDDSTLSY DIP protein O94985-2 original sequence version: 131 q91ys4_mouse Kinesin light chain Klc2 protein protein mouse Mus musculus Mouse MATMVLPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLASHEAGEAEPGSQERCLLLRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKLQRSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEKGDVPKDSLDDLFPNEDEQSPAPSPGGGDVAAQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGENKPIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCASRSRKQGLDPASQTKVVELLKDGSGGRGHRRGSRDVAGPQSESDLEESGPAAEWSGDGSGSLRRSGSFGKLRDALRRSSEMLVRKLQGGGPQEPPNSRMKRASSLNFLNKSVEEPVQPGGTGLSDSRTLSSSSMDLSRRSSLVG DIP protein Q91YS4 original sequence version: 101 A3C2B941BECDB178 pkhm2_human Pleckstrin homology domain-containing family M member 2 KIAA0842 SKIP Salmonella-induced filaments A and kinesin-interacting protein PLEKHM2 protein protein human Homo sapiens Human MEPGEVKDRILENISLSVKKLQSYFAACEDEIPAIRNHDKVLQRLCEHLDHALLYGLQDLSSGYWVLVVHFTRREAIKQIEVLQHVATNLGRSRAWLYLALNENSLESYLRLFQENLGLLHKYYVKNALVCSHDHLTLFLTLVSGLEFIRFELDLDAPYLDLAPYMPDYYKPQYLLDFEDRLPSSVHGSDSLSLNSFNSVTSTNLEWDDSAIAPSSEDYDFGDVFPAVPSVPSTDWEDGDLTDTVSGPRSTASDLTSSKASTRSPTQRQNPFNEEPAETVSSSDTTPVHTTSQEKEEAQALDPPDACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQKKCAKQGDGDSRNGSPSLGRDSPDTMLASPQEEGEGPSSTTESSERSEPGLLIPEMKDTSMERLGQPLSKVIDQLNGQLDPSTWCSRAEPPDQSFRTGSPGDAPERPPLCDFSEGLSAPMDFYRFTVESPSTVTSGGGHHDPAGLGQPLHVPSSPEAAGQEEEGGGGEGQTPRPLEDTTREAQELEAQLSLVREGPVSEPEPGTQEVLCQLKRDQPSPCLSSAEDSGVDEGQGSPSEMVHSSEFRVDNNHLLLLMIHVFRENEEQLFKMIRMSTGHMEGNLQLLYVLLTDCYVYLLRKGATEKPYLVEEAVSYNELDYVSVGLDQQTVKLVCTNRRKQFLLDTADVALAEFFLASLKSAMIKGCREPPYPSILTDATMEKLALAKFVAQESKCEASAVTVRFYGLVHWEDPTDESLGPTPCHCSPPEGTITKEGMLHYKAGTSYLGKEHWKTCFVVLSNGILYQYPDRTDVIPLLSVNMGGEQCGGCRRANTTDRPHAFQVILSDRPCLELSAESEAEMAEWMQHLCQAVSKGVIPQGVAPSPCIPCCLVLTDDRLFTCHEDCQTSFFRSLGTAKLGDISAVSTEPGKEYCVLEFSQDSQQLLPPWVIYLSCTSELDRLLSALNSGWKTIYQVDLPHTAIQEASNKKKFEDALSLIHSAWQRSDSLCRGRASRDPWC DIP protein Q8IWE5 original sequence version: 33 DIP protein Q8IWE5 original sequence version: 97 FFD857F4C11BC0DB klc2-plekhm2-1 5 8 unspecified role unspecified role unspecified role unspecified role Region 218-480 Region 218-480 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain Q91YS4:p.Arg251Asp R251D mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain R D This feature has been corrected as a result of our quality control procedures. The original label was 'R251D'. Wed May 02 19:20:03 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'arg251asp' Tue Jun 30 18:01:55 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Arg251Asp' Q91YS4:p.Asn287Leu N287L mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain N L This feature has been corrected as a result of our quality control procedures. The original label was 'N287L'. Wed May 02 19:30:22 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'asn287leu' Tue Jun 30 18:10:08 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Asn287Leu' Q91YS4:p.Arg312Glu R312E mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain R E This feature has been corrected as a result of our quality control procedures. The original label was 'R312E'. Wed May 02 19:07:30 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'arg312glu' Tue Jun 30 17:59:27 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Arg312Glu' ecolx Escherichia coli 9 unspecified role unspecified role unspecified role unspecified role Region 202-212 Region 202-212 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain TAMRA-label TAMRA-label tetramethyl rhodamine label tetramethyl rhodamine label n-term range n-terminal range n-term range n-term range n-terminal range n-term range in vitro In vitro direct interaction direct interaction plekhm2-klc2-1 2 8 unspecified role unspecified role prey prey HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human 9 unspecified role unspecified role bait bait Q8IWE5:p.[Trp207Ala;Asp208Ala] W207A/D208A mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain D A certain certain sequence position certain certain certain sequence position certain W A This feature has been corrected as a result of our quality control procedures. The original label was 'W207A/D208A'. Wed May 02 15:15:09 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'trp207ala,asp208ala' Tue Jun 30 19:31:20 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Trp207Ala;Asp208Ala]' Q8IWE5:p.[Trp207Ala;Asp208Ala;Trp236Ala;Glu237Ala] W207A/D208A/W236A/E237A mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain E A certain certain sequence position certain certain certain sequence position certain W A certain certain sequence position certain certain certain sequence position certain D A certain certain sequence position certain certain certain sequence position certain W A This feature has been corrected as a result of our quality control procedures. The original label was 'W207A/D208A/W236A/E237A'. Wed May 02 16:25:37 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'trp207ala,asp208ala,trp236ala,glu237ala' Tue Jun 30 19:18:31 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Trp207Ala;Asp208Ala;Trp236Ala;Glu237Ala]' GFP-tag GFP-tag gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range Region 1-310 Region 1-310 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human physical association physical association klc2-plekhm2-2 3 8 unspecified role unspecified role unspecified role unspecified role Region 218-480 Region 218-480 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 9 unspecified role unspecified role unspecified role unspecified role Region 202-212 Region 202-212 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain Region 231-241 Region 231-241 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain TAMRA-label TAMRA-label tetramethyl rhodamine label tetramethyl rhodamine label n-term range n-terminal range n-term range n-term range n-terminal range n-term range in vitro In vitro direct interaction direct interaction plekhm2-klc2-2 1 8 unspecified role unspecified role prey prey HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range Q91YS4:p.Arg251Asp R251D mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain R D This feature has been corrected as a result of our quality control procedures. The original label was 'R251D'. Wed May 02 15:01:16 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'arg251asp' Tue Jun 30 18:20:49 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Arg251Asp' Q91YS4:p.Asn287Leu N287L mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain N L This feature has been corrected as a result of our quality control procedures. The original label was 'N287L'. Wed May 02 14:40:04 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'asn287leu' Tue Jun 30 17:01:11 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Asn287Leu' Q91YS4:p.Val290Lys V290K mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain V K This feature has been corrected as a result of our quality control procedures. The original label was 'V290K'. Wed May 02 15:10:17 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'val290lys' Tue Jun 30 16:15:02 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Val290Lys' Q91YS4:p.Leu291Asp L291D mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain L D This feature has been corrected as a result of our quality control procedures. The original label was 'L291D'. Wed May 02 14:57:37 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu291asp' Tue Jun 30 18:02:48 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Leu291Asp' Q91YS4:p.Arg312Glu R312E mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain R E This feature has been corrected as a result of our quality control procedures. The original label was 'R312E'. Wed May 02 20:08:13 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'arg312glu' Tue Jun 30 17:30:27 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Arg312Glu' Q91YS4:p.Arg312Ala R312A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain R A This feature has been corrected as a result of our quality control procedures. The original label was 'R312A'. Wed May 02 16:30:08 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'arg312ala' Tue Jun 30 15:47:44 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Arg312Ala' Q91YS4:p.Lys325Glu K325E mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain K E This feature has been corrected as a result of our quality control procedures. The original label was 'K325E'. Wed May 02 17:01:01 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'lys325glu' Tue Jun 30 16:50:22 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Lys325Glu' Q91YS4:p.Leu333Lys L333K mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain L K This feature has been corrected as a result of our quality control procedures. The original label was 'L333K'. Wed May 02 16:37:03 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu333lys' Tue Jun 30 20:21:11 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Leu333Lys' human Homo sapiens Human 9 unspecified role unspecified role bait bait GFP-tag GFP-tag gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range Region 1-310 Region 1-310 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human physical association physical association clstn1-klc2-1 4 7 unspecified role unspecified role bait bait Region 879-971 Region 879-971 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain GFP-tag GFP-tag gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human Homo sapiens Human 8 unspecified role unspecified role prey prey HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range Q91YS4:p.Arg251Asp R251D mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain R D This feature has been corrected as a result of our quality control procedures. The original label was 'R251D'. Wed May 02 18:30:39 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'arg251asp' Tue Jun 30 16:26:10 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Arg251Asp' Q91YS4:p.Asn287Leu N287L mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain N L This feature has been corrected as a result of our quality control procedures. The original label was 'N287L'. Wed May 02 20:31:25 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'asn287leu' Tue Jun 30 18:14:53 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Asn287Leu' Q91YS4:p.Arg312Glu R312E mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain R E This feature has been corrected as a result of our quality control procedures. The original label was 'R312E'. Wed May 02 18:32:03 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'arg312glu' Tue Jun 30 15:55:57 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Arg312Glu' human Homo sapiens Human physical association physical association clstn1-klc2-2 6 7 unspecified role unspecified role unspecified role unspecified role Region 888-898 Region 888-898 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain TAMRA-label TAMRA-label tetramethyl rhodamine label tetramethyl rhodamine label undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Region 959-969 Region 959-969 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain in vitro In vitro 8 unspecified role unspecified role unspecified role unspecified role Region 218-480 Region 218-480 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain Q91YS4:p.Arg251Asp R251D mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain R D This feature has been corrected as a result of our quality control procedures. The original label was 'R251D'. Wed May 02 16:49:46 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'arg251asp' Tue Jun 30 18:33:33 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Arg251Asp' Q91YS4:p.Asn287Leu N287L mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain N L This feature has been corrected as a result of our quality control procedures. The original label was 'N287L'. Wed May 02 18:27:41 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'asn287leu' Tue Jun 30 17:39:09 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Asn287Leu' Q91YS4:p.Arg312Glu R312E mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain R E This feature has been corrected as a result of our quality control procedures. The original label was 'R312E'. Wed May 02 15:21:42 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'arg312glu' Tue Jun 30 18:09:39 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Arg312Glu' ecolx Escherichia coli direct interaction direct interaction