DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Structural basis for recognition of 5'-phosphotyrosine adducts by Tdp2. Structural basis for recognition of 5'-phosphotyrosine adducts by Tdp2. Nature structural & molecular biology 2012 imex curation Shi K., Kurahashi K., Gao R., Tsutakawa SE., Tainer JA., Pommier Y., Aihara H. Only protein-protein interactions ecolx Escherichia coli saxs x ray scattering saxs predetermined predetermined participant predetermined Shi K., Kurahashi K., Gao R., Tsutakawa SE., Tainer JA., Pommier Y., Aihara H. DIP original experiment: DIP-251380X Nature structural & molecular biology 2012 IMEx Structural basis for recognition of 5'-phosphotyrosine adducts by Tdp2. Structural basis for recognition of 5'-phosphotyrosine adducts by Tdp2. Structural basis for recognition of 5'-phosphotyrosine adducts by Tdp2. Nature structural & molecular biology 2012 imex curation Shi K., Kurahashi K., Gao R., Tsutakawa SE., Tainer JA., Pommier Y., Aihara H. Only protein-protein interactions ecolx Escherichia coli x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Shi K., Kurahashi K., Gao R., Tsutakawa SE., Tainer JA., Pommier Y., Aihara H. DIP original experiment: DIP-251381X Nature structural & molecular biology 2012 IMEx Structural basis for recognition of 5'-phosphotyrosine adducts by Tdp2. Structural basis for recognition of 5'-phosphotyrosine adducts by Tdp2. Structural basis for recognition of 5'-phosphotyrosine adducts by Tdp2. Nature structural & molecular biology 2012 imex curation Shi K., Kurahashi K., Gao R., Tsutakawa SE., Tainer JA., Pommier Y., Aihara H. Only protein-protein interactions ecolx Escherichia coli molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Shi K., Kurahashi K., Gao R., Tsutakawa SE., Tainer JA., Pommier Y., Aihara H. DIP original experiment: DIP-251379X Nature structural & molecular biology 2012 IMEx Structural basis for recognition of 5'-phosphotyrosine adducts by Tdp2. tydp2_caeel 5'-tyrosyl-DNA phosphodiesterase Y63D3A.4 protein protein caeel Caenorhabditis elegans MSNSDDEIQEIEAKRQKMSQEDSEVEIEILDEPEQGKLKNSSMSDEQKLHEFAIITATDEAFAQSILQDVDWDLKKALDVFYGSEAFAEARSAAVMGASSSMASSGAAVMTAEDLKGFEVSVMSWNIDGLDGRSLLTRMKAVAHIVKNVNPDILFLQEVVDRDLAPIDKLQSLYKIYYSNKGCQYYTAILVSKMFDVEKHDVIHFQNSGMYRTLQILEGSIGGLKVFLLNTHLESTREHRPQRCAQFGFCMDKVREIIAQNPGALVFFGGDLNLRDEEVSRVPDGVKDAWEAAGSDNKTKFTWDTFKNDNKQGFHGAKMRFDRLYWSGPLDKVKFTLEGRQRIRSCLCFPSDHWAINATFFA DIP protein Q9XWG3 original sequence version: 74 7895C47504866E52 tydp2_caeel-1 3 4 unspecified role unspecified role unspecified role unspecified role Region 1-106 Region 1-106 required to bind necessary binding region required to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction tydp2_caeel-2 1 4 unspecified role unspecified role unspecified role unspecified role Region1-106 Region1-106 required to bind necessary binding region required to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction tydp2_caeel-3 2 4 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction