DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nature structural & molecular biology 2012 imex curation Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. Only protein-protein interactions human Homo sapiens Human solution sedimentati cosedimentation in solution solution sedimentati predetermined predetermined participant predetermined Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. DIP original experiment: DIP-251125X Nature structural & molecular biology 2012 IMEx Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nature structural & molecular biology 2012 imex curation Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. Only protein-protein interactions in vitro In vitro spr surface plasmon resonance Optical biosensor BIAcore(r) BIAcore(r) Optical biosensor spr predetermined predetermined participant predetermined Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. DIP original experiment: DIP-251137X Nature structural & molecular biology 2012 IMEx Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nature structural & molecular biology 2012 imex curation Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. Only protein-protein interactions human Homo sapiens Human solution sedimentati cosedimentation in solution solution sedimentati predetermined predetermined participant predetermined Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. DIP original experiment: DIP-251124X Nature structural & molecular biology 2012 IMEx Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nature structural & molecular biology 2012 imex curation Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. Only protein-protein interactions in vitro In vitro spr surface plasmon resonance Optical biosensor BIAcore(r) BIAcore(r) Optical biosensor spr predetermined predetermined participant predetermined Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. DIP original experiment: DIP-251138X Nature structural & molecular biology 2012 IMEx Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nature structural & molecular biology 2012 imex curation Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. Only protein-protein interactions in vitro In vitro spr surface plasmon resonance Optical biosensor BIAcore(r) BIAcore(r) Optical biosensor spr predetermined predetermined participant predetermined Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. DIP original experiment: DIP-251140X Nature structural & molecular biology 2012 IMEx Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nature structural & molecular biology 2012 imex curation Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. Only protein-protein interactions in vitro In vitro spr surface plasmon resonance Optical biosensor BIAcore(r) BIAcore(r) Optical biosensor spr predetermined predetermined participant predetermined Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. DIP original experiment: DIP-251131X Nature structural & molecular biology 2012 IMEx Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nature structural & molecular biology 2012 imex curation Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. Only protein-protein interactions human Homo sapiens Human x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. DIP original experiment: DIP-251129X Nature structural & molecular biology 2012 IMEx Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nature structural & molecular biology 2012 imex curation Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. Only protein-protein interactions in vitro In vitro spr surface plasmon resonance Optical biosensor BIAcore(r) BIAcore(r) Optical biosensor spr predetermined predetermined participant predetermined Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. DIP original experiment: DIP-251135X Nature structural & molecular biology 2012 IMEx Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nature structural & molecular biology 2012 imex curation Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. Only protein-protein interactions human Homo sapiens Human x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. DIP original experiment: DIP-251128X Nature structural & molecular biology 2012 IMEx Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nature structural & molecular biology 2012 imex curation Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. Only protein-protein interactions in vitro In vitro spr surface plasmon resonance Optical biosensor BIAcore(r) BIAcore(r) Optical biosensor spr predetermined predetermined participant predetermined Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. DIP original experiment: DIP-251139X Nature structural & molecular biology 2012 IMEx Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nature structural & molecular biology 2012 imex curation Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. Only protein-protein interactions in vitro In vitro solution sedimentati cosedimentation in solution solution sedimentati predetermined predetermined participant predetermined Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. DIP original experiment: DIP-251127X Nature structural & molecular biology 2012 IMEx Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nature structural & molecular biology 2012 imex curation Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. Only protein-protein interactions human Homo sapiens Human x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. DIP original experiment: DIP-251130X Nature structural & molecular biology 2012 IMEx Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nature structural & molecular biology 2012 imex curation Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. Only protein-protein interactions in vitro In vitro spr surface plasmon resonance Optical biosensor BIAcore(r) BIAcore(r) Optical biosensor spr predetermined predetermined participant predetermined Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. DIP original experiment: DIP-251134X Nature structural & molecular biology 2012 IMEx Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nature structural & molecular biology 2012 imex curation Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. Only protein-protein interactions human Homo sapiens Human solution sedimentati cosedimentation in solution solution sedimentati predetermined predetermined participant predetermined Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. DIP original experiment: DIP-251118X Nature structural & molecular biology 2012 IMEx Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nature structural & molecular biology 2012 imex curation Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. Only protein-protein interactions human Homo sapiens Human solution sedimentati cosedimentation in solution solution sedimentati predetermined predetermined participant predetermined Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. DIP original experiment: DIP-251123X Nature structural & molecular biology 2012 IMEx Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nature structural & molecular biology 2012 imex curation Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. DIP original experiment: DIP-251143X Nature structural & molecular biology 2012 IMEx Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nature structural & molecular biology 2012 imex curation Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. Only protein-protein interactions human Homo sapiens Human solution sedimentati cosedimentation in solution solution sedimentati predetermined predetermined participant predetermined Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. DIP original experiment: DIP-251119X Nature structural & molecular biology 2012 IMEx Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nature structural & molecular biology 2012 imex curation Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. Only protein-protein interactions in vitro In vitro spr surface plasmon resonance Optical biosensor BIAcore(r) BIAcore(r) Optical biosensor spr predetermined predetermined participant predetermined Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. DIP original experiment: DIP-251132X Nature structural & molecular biology 2012 IMEx Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nature structural & molecular biology 2012 imex curation Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. Only protein-protein interactions human Homo sapiens Human x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. DIP original experiment: DIP-251121X Nature structural & molecular biology 2012 IMEx Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nature structural & molecular biology 2012 imex curation Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. Only protein-protein interactions human Homo sapiens Human solution sedimentati cosedimentation in solution solution sedimentati predetermined predetermined participant predetermined Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. DIP original experiment: DIP-251120X Nature structural & molecular biology 2012 IMEx Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nature structural & molecular biology 2012 imex curation Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. Only protein-protein interactions human Homo sapiens Human solution sedimentati cosedimentation in solution solution sedimentati predetermined predetermined participant predetermined Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. DIP original experiment: DIP-251117X Nature structural & molecular biology 2012 IMEx Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nature structural & molecular biology 2012 imex curation Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. Only protein-protein interactions in vitro In vitro solution sedimentati cosedimentation in solution solution sedimentati predetermined predetermined participant predetermined Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. DIP original experiment: DIP-251126X Nature structural & molecular biology 2012 IMEx Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nature structural & molecular biology 2012 imex curation Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. Only protein-protein interactions in vitro In vitro spr surface plasmon resonance Optical biosensor BIAcore(r) BIAcore(r) Optical biosensor spr predetermined predetermined participant predetermined Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. DIP original experiment: DIP-251133X Nature structural & molecular biology 2012 IMEx Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nature structural & molecular biology 2012 imex curation Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. Only protein-protein interactions in vitro In vitro spr surface plasmon resonance Optical biosensor BIAcore(r) BIAcore(r) Optical biosensor spr predetermined predetermined participant predetermined Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. DIP original experiment: DIP-251142X Nature structural & molecular biology 2012 IMEx Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nature structural & molecular biology 2012 imex curation Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. Only protein-protein interactions in vitro In vitro spr surface plasmon resonance Optical biosensor BIAcore(r) BIAcore(r) Optical biosensor spr predetermined predetermined participant predetermined Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. DIP original experiment: DIP-251136X Nature structural & molecular biology 2012 IMEx Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nature structural & molecular biology 2012 imex curation Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. Only protein-protein interactions human Homo sapiens Human solution sedimentati cosedimentation in solution solution sedimentati predetermined predetermined participant predetermined Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. DIP original experiment: DIP-251122X Nature structural & molecular biology 2012 IMEx Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nectin ectodomain structures reveal a canonical adhesive interface. Nature structural & molecular biology 2012 imex curation Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. Only protein-protein interactions in vitro In vitro spr surface plasmon resonance Optical biosensor BIAcore(r) BIAcore(r) Optical biosensor spr predetermined predetermined participant predetermined Harrison OJ., Vendome J., Brasch J., Jin X., Hong S., Katsamba PS., Ahlsen G., Troyanovsky RB., Troyanovsky SM., Honig B., Shapiro L. DIP original experiment: DIP-251141X Nature structural & molecular biology 2012 IMEx Nectin ectodomain structures reveal a canonical adhesive interface. q9nqs3-1 Nectin-3 NECTIN3 PRR3 PVRL3 CDw113 Nectin cell adhesion molecule 3 Poliovirus receptor-related protein 3 protein protein human Homo sapiens Human MARTLRPSPLCPGGGKAQLSSASLLGAGLLLQPPTPPPLLLLLFPLLLFSRLCGALAGPIIVEPHVTAVWGKNVSLKCLIEVNETITQISWEKIHGKSSQTVAVHHPQYGFSVQGEYQGRVLFKNYSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAICIAATGKPVAHIDWEGDLGEMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPPTTTTLQPTIQWHPSTADIEDLATEPKKLPFPLSTLATIKDDTIATIIASVVGGALFIVLVSVLAGIFCYRRRRTFRGDYFAKNYIPPSDMQKESQIDVLQQDELDSYPDSVKKENKNPVNNLIRKDYLEEPEKTQWNNVENLNRFERPMDYYEDLKMGMKFVSDEHYDENEDDLVSHVDGSVISRREWYV DIP protein Q9NQS3-1 original sequence version: 86 p32507-2 Nectin-2 Nectin2 Herpes virus entry mediator B Mph Murine herpes virus entry protein B Nectin cell adhesion molecule 2 Poliovirus receptor homolog Poliovirus receptor-related protein 2 Pvr Pvrl2 Pvs protein protein mouse Mus musculus Mouse MARAAVLPPSRLSPTLPLLPLLLLLLQETGAQDVRVRVLPEVRGRLGGTVELPCHLLPPTTERVSQVTWQRLDGTVVAAFHPSFGVDFPNSQFSKDRLSFVRARPETNADLRDATLAFRGLRVEDEGNYTCEFATFPNGTRRGVTWLRVIAQPENHAEAQEVTIGPQSVAVARCVSTGGRPPARITWISSLGGEAKDTQEPGIQAGTVTIISRYSLVPVGRADGVKVTCRVEHESFEEPILLPVTLSVRYPPEVSISGYDDNWYLGRSEAILTCDVRSNPEPTDYDWSTTSGVFPASAVAQGSQLLVHSVDRMVNTTFICTATNAVGTGRAEQVILVRDTPQASRDVGPLVWGAVGGTLLVLLLAGGFLALILLRGRRRRKSPGGGGNDGDRGSYDPKTQVFGNGGPVFWRSASPEPMRPDGREEDEEEEEEMKAEEGLMLPPHESPKDDMESHLDGSLISRRAVYV DIP protein P32507-2 original sequence version: 114 7DB2430F6FFDD333 q9jlb9-1 Nectin-3 Nectin3 Pvrl3 Nectin-3 alpha Nectin cell adhesion molecule 3 Poliovirus receptor-related protein 3 protein protein mouse Mus musculus Mouse MARTPGPAPLCPGGGKAQLSSAFPPAAGLLLPAPTPPPLLLLLIPLLLFSRLCGALAGSIIVEPHVTAVWGKNVSLKCLIEVNETITQISWEKIHGKSTQTVAVHHPQYGFSVQGDYQGRVLFKNYSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAVCVAATGKPVAQIDWEGDLGEMESSTTSFPNETATIVSQYKLFPTRFARGRRITCVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPDGLLASDNTLHFVHPLTVNYSGVYVCKVSNSLGQRSDQKVIYISDPPTTTTLQPTVQWHSSPADVQDIATEHKKLPFPLSTLATLKDDTIGTIIASVVGGALFLVLVSILAGVFCYRRRRTFRGDYFAKNYIPPSDMQKESQIDVLHQDELDSYPDSVKKENKNPVNNLIRKDYLEEPEKTQWNNVENLTRFERPMDYYEDLKMGMKFVSDERYNESEDGLVSHVDGSVISRREWYV DIP protein Q9JLB9-1 original sequence version: 88 nect4_human Nectin-4 NECTIN4 Ig superfamily receptor LNIR LNIR Nectin cell adhesion molecule 4 PRR4 PVRL4 Poliovirus receptor-related protein 4 protein protein human Homo sapiens Human MPLSLGAEMWGPEAWLLLLLLLASFTGRCPAGELETSDVVTVVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRLDGPLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSGKQVDLVSASVVVVGVIAALLFCLLVVVVVLMSRYHRRKAQQMTQKYEEELTLTRENSIRRLHSHHTDPRSQPEESVGLRAEGHPDSLKDNSSCSVMSEEPEGRSYSTLTTVREIETQTELLSPGSGRAEEEEDQDEGIKQAMNHFVQENGTLRAKPTGNGIYINGRGHLV DIP protein Q96NY8 original sequence version: 100 DIP protein Q96NY8 original sequence version: 105 DIP protein Q96NY8 original sequence version: 90 DIP protein Q96NY8 original sequence version: 97 DCF5E1D794F227FA nect4_mouse Nectin-4 Nectin4 Lnir Prr4 Pvrl4 Nectin cell adhesion molecule 4 Poliovirus receptor-related protein 4 Ig superfamily receptor LNIR protein protein mouse Mus musculus Mouse MPLSLGAEMWGPEAWLRLLFLASFTGQYSAGELETSDVVTVVLGQDAKLPCFYRGDPDEQVGQVAWARVDPNEGIRELALLHSKYGLHVNPAYEDRVEQPPPPRDPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARMRLRVLVPPLPSLNPGPPLEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTQSSRSFTHPRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDRRITHTLQVAFLAEASVRGLEDQNLWQVGREGATLKCLSEGQPPPKYNWTRLDGPLPSGVRVKGDTLGFPPLTTEHSGVYVCHVSNELSSRDSQVTVEVLDPEDPGKQVDLVSASVIIVGVIAALLFCLLVVVVVLMSRYHRRKAQQMTQKYEEELTLTRENSIRRLHSHHSDPRSQPEESVGLRAEGHPDSLKDNSSCSVMSEEPEGRSYSTLTTVREIETQTELLSPGSGRTEEDDDQDEGIKQAMNHFVQENGTLRAKPTGNGIYINGRGHLV DIP protein Q8R007 original sequence version: 84 nect1_mouse Nectin-1 Nectin1 Herpes virus entry mediator C Hvec Nectin cell adhesion molecule 1 Poliovirus receptor-related protein 1 Prr1 Pvrl1 protein protein mouse Mus musculus Mouse MARMGLAGAAGRWWGLALGLTAFFLPGTHTQVVQVNDSMYGFIGTDVVLHCSFANPLPSVKITQVTWQKASNGSKQNMAIYNPTMGVSVLPPYEKRVEFLRPSFIDGTIRLSGLELEDEGMYICEFATFPTGNRESQLNLTVMAKPTNWIEGTRAVLRARKGQDDKVLVATCTSANGKPPSAVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHRQSLACIVNYHLDRFRESLTLNVQYEPEVTIEGFDGNWYLQRTDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFRGPITYSLAGTYICEATNPIGTRSGQVEVNITEFPYTPTPEHGRRAGQMPTAIIGGVAGSVLLVLIVVGGIIVALRRRRHTFKGDYSTKKHVYGNGYSKAGIPQHHPPMAQNLQYPDDSDDEKKAGPLGGSSYEEEEEEEGGGGGERKVGGPHPKYDEDAKRPYFTVDEAEARQDGYGDRTLGYQYDPEQLDLAENMVSQNDGSFISKKEWYV DIP protein Q9JKF6 original sequence version: 108 mint Probably involved in cell adhesion. Receptor for alphaherpesvirus (HSV-1, HSV-2 and pseudorabies virus) entry into cells A56FA2C7F8B25AFB nect1_human Nectin-1 NECTIN1 HVEC Herpes virus entry mediator C Herpesvirus Ig-like receptor Nectin cell adhesion molecule 1 PRR1 PVRL1 Poliovirus receptor-related protein 1 protein protein human Homo sapiens Human MARMGLAGAAGRWWGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVKITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEFPYTPSPPEHGRRAGPVPTAIIGGVAGSILLVLIVVGGIVVALRRRRHTFKGDYSTKKHVYGNGYSKAGIPQHHPPMAQNLQYPDDSDDEKKAGPLGGSSYEEEEEEEEGGGGGERKVGGPHPKYDEDAKRPYFTVDEAEARQDGYGDRTLGYQYDPEQLDLAENMVSQNDGSFISKKEWYV DIP protein Q15223 original sequence version: 122 DF34C8AEC893EE6D pvr_human Poliovirus receptor PVR PVS Nectin-like protein 5 protein protein human Homo sapiens Human MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGISRNAIIFLVLGILVFLILLGIGIYFYWSKCSREVLWHCHLCPSSTEHASASANGHVSYSAVSRENSSSQDPQTEGTR DIP protein P15151 original sequence version: 140 D15C012CE853169B nect2_human Nectin-2 NECTIN2 HVEB Herpes virus entry mediator B Nectin cell adhesion molecule 2 PRR2 PVRL2 Poliovirus receptor-related protein 2 protein protein human Homo sapiens Human MARAAALLPSRSPPTPLLWPLLLLLLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPVPGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAGAGATGGIIGGIIAAIIATAVAATGILICRQQRKEQTLQGAEEDEDLEGPPSYKPPTPKAKLEAQEMPSQLFTLGASEHSPLKTPYFDAGASCTEQEMPRYHELPTLEERSGPLHPGATSLGSPIPVPPGPPAVEDVSLDLEDEEGEEEEEYLDKINPIYDALSYSSPSDSYQGKGFVMSRAMYV DIP protein Q92692 original sequence version: 131 DIP protein Q92692 original sequence version: 134 3AE4F83E92F6F624 nectin1-1 21 33 unspecified role unspecified role unspecified role unspecified role Ectodomain Region 31-337 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human direct interaction direct interaction nectin3-1 7 28 unspecified role unspecified role unspecified role unspecified role Ectodomain Region 58-359 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human direct interaction direct interaction nectin2-nectin3-1 4 36 unspecified role unspecified role bait bait Ectodomain Region 32-350 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human 28 unspecified role unspecified role prey prey Ectodomain Region 58-359 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human direct interaction direct interaction nectin1-2 9 34 unspecified role unspecified role unspecified role unspecified role Ectodomain Region 31-337 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human direct interaction direct interaction nectin2-1 14 29 unspecified role unspecified role unspecified role unspecified role Ectodomain Region 32-250 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain P32507-2:p.Phe136Asp F136D mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain F D This feature has been corrected as a result of our quality control procedures. The original label was 'F136D'. Wed May 02 18:49:44 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe136asp' Tue Jun 30 16:11:35 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Phe136Asp' human Homo sapiens Human direct interaction direct interaction nectin3-nectin2-1 2 36 unspecified role unspecified role prey prey Ectodomain Region 32-350 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human 28 unspecified role unspecified role bait bait Ectodomain Region 58-359 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human direct interaction direct interaction nectin3-2 17 30 unspecified role unspecified role unspecified role unspecified role Ectodomain Region 58-401 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human direct interaction direct interaction nectin4-1 12 31 unspecified role unspecified role unspecified role unspecified role Ectodomain Region 32-243 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human direct interaction direct interaction nectin4-3 20 32 unspecified role unspecified role unspecified role unspecified role Ectodomain Region 31-338 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human direct interaction direct interaction nectin3-nectin3-1 5 28 unspecified role unspecified role prey prey Ectodomain Region 58-359 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human 28 unspecified role unspecified role bait bait Ectodomain Region 58-359 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human direct interaction direct interaction nectin1-nectin3-1 6 34 unspecified role unspecified role bait bait Ectodomain Region 31-337 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain Q15223:p.Phe129Asp F136D mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain F D Wed May 02 14:34:01 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe129asp' Tue Jun 30 17:11:43 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Phe129Asp' human Homo sapiens Human 28 unspecified role unspecified role prey prey Ectodomain Region 58-359 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human direct interaction direct interaction nectin2-2 19 29 unspecified role unspecified role unspecified role unspecified role P32507-2:p.Phe136Asp F136D mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain F D This feature has been corrected as a result of our quality control procedures. The original label was 'F136D'. Wed May 02 19:28:41 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe136asp' Tue Jun 30 19:18:09 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Phe136Asp' Ectodomain Region 32-250 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human direct interaction direct interaction nectin2-nectin2-1 10 36 unspecified role unspecified role prey prey Ectodomain Region 32-350 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human 36 unspecified role unspecified role bait bait Ectodomain Region 32-350 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human direct interaction direct interaction nectin3-nectin1-1 18 34 unspecified role unspecified role prey prey Ectodomain Region 31-337 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human 28 unspecified role unspecified role bait bait Ectodomain Region 58-359 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human direct interaction direct interaction nectin1-3 26 34 unspecified role unspecified role unspecified role unspecified role Ectodomain Region 31-337 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain Q15223:p.Phe129Asp F136D mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain F D Wed May 02 16:02:55 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe129asp' Tue Jun 30 19:07:45 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Phe129Asp' human Homo sapiens Human direct interaction direct interaction nectin2-3 15 36 unspecified role unspecified role unspecified role unspecified role Ectodomain Region 32-350 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human direct interaction direct interaction nectin4-nectin4-1 24 31 unspecified role unspecified role prey prey Ectodomain Region 32-336 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human 31 unspecified role unspecified role bait bait Ectodomain Region 32-336 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human direct interaction direct interaction nectin3-3 3 28 unspecified role unspecified role unspecified role unspecified role Ectodomain Region 58-359 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human direct interaction direct interaction nectin1-nectin4-1 23 31 unspecified role unspecified role prey prey Ectodomain Region 32-336 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human 34 unspecified role unspecified role bait bait Ectodomain Region 31-337 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain Q15223:p.Phe129Asp F136D mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain F D Wed May 02 19:09:19 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe129asp' Tue Jun 30 20:09:14 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Phe129Asp' human Homo sapiens Human direct interaction direct interaction nectin1-nectin1-1 27 34 unspecified role unspecified role bait bait Ectodomain Region 31-337 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human 34 unspecified role unspecified role prey prey Ectodomain Region 31-337 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human direct interaction direct interaction nectin4-nectin1-1 13 31 unspecified role unspecified role bait bait Ectodomain Region 32-336 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human 34 unspecified role unspecified role prey prey Ectodomain Region 31-337 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human direct interaction direct interaction nectin4-4 1 31 unspecified role unspecified role unspecified role unspecified role Ectodomain Region 32-336 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human direct interaction direct interaction nectin1-nectin3-2 22 34 unspecified role unspecified role unspecified role unspecified role Ectodomain Region 31-337 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human 28 unspecified role unspecified role unspecified role unspecified role Ectodomain Region 58-359 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human direct interaction direct interaction pvr-nectin1-1 8 34 unspecified role unspecified role prey prey Ectodomain Region 31-337 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human 35 unspecified role unspecified role bait bait Ectodomain Region 21-334 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human direct interaction direct interaction nectin2-nectin2-2 16 29 unspecified role unspecified role prey prey Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined P32507-2:p.Leu72Cys L72C mutation mutation certain certain sequence position certain certain certain sequence position certain L C This feature has been corrected as a result of our quality control procedures. The original label was 'L72C'. Wed May 02 20:29:14 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu72cys' Tue Jun 30 19:02:27 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Leu72Cys' human Homo sapiens Human 29 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined P32507-2:p.Leu72Cys L72C mutation mutation certain certain sequence position certain certain certain sequence position certain L C This feature has been corrected as a result of our quality control procedures. The original label was 'L72C'. Wed May 02 15:55:45 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu72cys' Tue Jun 30 20:02:02 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Leu72Cys' human Homo sapiens Human physical association physical association nectin1-nectin4-2 11 31 unspecified role unspecified role unspecified role unspecified role Ectodomain Region 32-336 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human 34 unspecified role unspecified role unspecified role unspecified role Ectodomain Region 31-337 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human direct interaction direct interaction pvr-nectin3-1 25 28 unspecified role unspecified role prey prey Ectodomain Region 58-359 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human 35 unspecified role unspecified role bait bait Ectodomain Region 21-334 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human direct interaction direct interaction