DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu The human CST complex is a terminator of telomerase activity. The human CST complex is a terminator of telomerase activity. Nature 2012 imex curation Chen LY., Redon S., Lingner J. Only protein-protein interactions yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Chen LY., Redon S., Lingner J. DIP original experiment: DIP-250746X Nature 2012 IMEx The human CST complex is a terminator of telomerase activity. The human CST complex is a terminator of telomerase activity. The human CST complex is a terminator of telomerase activity. Nature 2012 imex curation Chen LY., Redon S., Lingner J. Only protein-protein interactions human Homo sapiens Human pull down pull down predetermined predetermined participant predetermined Chen LY., Redon S., Lingner J. DIP original experiment: DIP-250734X Nature 2012 IMEx The human CST complex is a terminator of telomerase activity. The human CST complex is a terminator of telomerase activity. The human CST complex is a terminator of telomerase activity. Nature 2012 imex curation Chen LY., Redon S., Lingner J. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Chen LY., Redon S., Lingner J. DIP original experiment: DIP-250738X Nature 2012 IMEx The human CST complex is a terminator of telomerase activity. The human CST complex is a terminator of telomerase activity. The human CST complex is a terminator of telomerase activity. Nature 2012 imex curation Chen LY., Redon S., Lingner J. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Chen LY., Redon S., Lingner J. DIP original experiment: DIP-250739X Nature 2012 IMEx The human CST complex is a terminator of telomerase activity. The human CST complex is a terminator of telomerase activity. The human CST complex is a terminator of telomerase activity. Nature 2012 imex curation Chen LY., Redon S., Lingner J. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip predetermined predetermined participant predetermined Chen LY., Redon S., Lingner J. DIP original experiment: DIP-250737X Nature 2012 IMEx The human CST complex is a terminator of telomerase activity. The human CST complex is a terminator of telomerase activity. The human CST complex is a terminator of telomerase activity. Nature 2012 imex curation Chen LY., Redon S., Lingner J. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Chen LY., Redon S., Lingner J. DIP original experiment: DIP-250742X Nature 2012 IMEx The human CST complex is a terminator of telomerase activity. The human CST complex is a terminator of telomerase activity. The human CST complex is a terminator of telomerase activity. Nature 2012 imex curation Chen LY., Redon S., Lingner J. Only protein-protein interactions human Homo sapiens Human pull down pull down predetermined predetermined participant predetermined Chen LY., Redon S., Lingner J. DIP original experiment: DIP-250736X Nature 2012 IMEx The human CST complex is a terminator of telomerase activity. The human CST complex is a terminator of telomerase activity. The human CST complex is a terminator of telomerase activity. Nature 2012 imex curation Chen LY., Redon S., Lingner J. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Chen LY., Redon S., Lingner J. DIP original experiment: DIP-250743X Nature 2012 IMEx The human CST complex is a terminator of telomerase activity. The human CST complex is a terminator of telomerase activity. The human CST complex is a terminator of telomerase activity. Nature 2012 imex curation Chen LY., Redon S., Lingner J. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Chen LY., Redon S., Lingner J. DIP original experiment: DIP-250740X Nature 2012 IMEx The human CST complex is a terminator of telomerase activity. The human CST complex is a terminator of telomerase activity. The human CST complex is a terminator of telomerase activity. Nature 2012 imex curation Chen LY., Redon S., Lingner J. Only protein-protein interactions yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Chen LY., Redon S., Lingner J. DIP original experiment: DIP-250744X Nature 2012 IMEx The human CST complex is a terminator of telomerase activity. The human CST complex is a terminator of telomerase activity. The human CST complex is a terminator of telomerase activity. Nature 2012 imex curation Chen LY., Redon S., Lingner J. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Chen LY., Redon S., Lingner J. DIP original experiment: DIP-250741X Nature 2012 IMEx The human CST complex is a terminator of telomerase activity. The human CST complex is a terminator of telomerase activity. The human CST complex is a terminator of telomerase activity. Nature 2012 imex curation Chen LY., Redon S., Lingner J. Only protein-protein interactions yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Chen LY., Redon S., Lingner J. DIP original experiment: DIP-250747X Nature 2012 IMEx The human CST complex is a terminator of telomerase activity. The human CST complex is a terminator of telomerase activity. The human CST complex is a terminator of telomerase activity. Nature 2012 imex curation Chen LY., Redon S., Lingner J. Only protein-protein interactions yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Chen LY., Redon S., Lingner J. DIP original experiment: DIP-250745X Nature 2012 IMEx The human CST complex is a terminator of telomerase activity. The human CST complex is a terminator of telomerase activity. The human CST complex is a terminator of telomerase activity. Nature 2012 imex curation Chen LY., Redon S., Lingner J. Only protein-protein interactions yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Chen LY., Redon S., Lingner J. DIP original experiment: DIP-250748X Nature 2012 IMEx The human CST complex is a terminator of telomerase activity. The human CST complex is a terminator of telomerase activity. The human CST complex is a terminator of telomerase activity. Nature 2012 imex curation Chen LY., Redon S., Lingner J. Only protein-protein interactions human Homo sapiens Human density sedimentation cosedimentation through density gradient density sedimentation predetermined predetermined participant predetermined Chen LY., Redon S., Lingner J. DIP original experiment: DIP-250735X Nature 2012 IMEx The human CST complex is a terminator of telomerase activity. o14773-1 Tripeptidyl-peptidase 1 TPP1 CLN2 Cell growth-inhibiting gene 1 protein Lysosomal pepstatin-insensitive protease Tripeptidyl aminopeptidase Tripeptidyl-peptidase I GIG1 UNQ267/PRO304 protein protein human Homo sapiens Human MGLQACLLGLFALILSGKCSYSPEPDQRRTLPPGWVSLGRADPEEELSLTFALRQQNVERLSELVQAVSDPSSPQYGKYLTLENVADLVRPSPLTLHTVQKWLLAAGAQKCHSVITQDFLTCWLSIRQAELLLPGAEFHHYVGGPTETHVVRSPHPYQLPQALAPHVDFVGGLHRFPPTSSLRQRPEPQVTGTVGLHLGVTPSVIRKRYNLTSQDVGSGTSNNSQACAQFLEQYFHDSDLAQFMRLFGGNFAHQASVARVVGQQGRGRAGIEASLDVQYLMSAGANISTWVYSSPGRHEGQEPFLQWLMLLSNESALPHVHTVSYGDDEDSLSSAYIQRVNTELMKAAARGLTLLFASGDSGAGCWSVSGRHQFRPTFPASSPYVTTVGGTSFQEPFLITNEIVDYISGGGFSNVFPRPSYQEEAVTKFLSSSPHLPPSSYFNASGRAYPDVAALSDGYWVVSNRVPIPWVSGTSASTPVFGGILSLINEHRILSGRPPLGFLNPRLYQQHGAGLFDVTRGCHESCLDEEVEGQGFCSGPGWDPVTGWGTPNFPALLKTLLNP DIP protein O14773-1 original sequence version: 143 DIP protein O14773-1 original sequence version: 133 ten1l_human CST complex subunit TEN1 TEN1 C17orf106 Telomere length regulation protein TEN1 homolog Protein telomeric pathways with STN1 homolog protein protein human Homo sapiens Human MMLPKPGTYYLPWEVSAGQVPDGSTLRTFGRLCLYDMIQSRVTLMAQHGSDQHQVLVCTKLVEPFHAQVGSLYIVLGELQHQQDRGSVVKARVLTCVEGMNLPLLEQAIREQRLYKQERGGSQ DIP protein Q86WV5 original sequence version: 53 C713E9B40C2A5E34 q9nux5-1 Protection of telomeres protein 1 POT1 POT1-like telomere end-binding protein Variant 1 protein protein human Homo sapiens Human MSLVPATNYIYTPLNQLKGGTIVNVYGVVKFFKPPYLSKGTDYCSVVTIVDQTNVKLTCLLFSGNYEALPIIYKNGDIVRFHRLKIQVYKKETQGITSSGFASLTFEGTLGAPIIPRTSSKYFNFTTEDHKMVEALRVWASTHMSPSWTLLKLCDVQPMQYFDLTCQLLGKAEVDGASFLLKVWDGTRTPFPSWRVLIQDLVLEGDLSHIHRLQNLTIDILVYDNHVHVARSLKVGSFLRIYSLHTKLQSMNSENQTMLSLEFHLHGGTSYGRGIRVLPESNSDVDQLKKDLESANLTANQHSDVICQSEPDDSFPSSGSVSLYEVERCQQLSATILTDHQYLERTPLCAILKQKAPQQYRIRAKLRSYKPRRLFQSVKLHCPKCHLLQEVPHEGDLDIIFQDGATKTPDVKLQNTSLYDSKIWTTKNQKGRKVAVHFVKNNGILPLSNECLLLIEGGTLSEICKLSNKFNSVIPVRSGHEDLELLDLSAPFLIQGTIHHYGCKQCSSLRSIQNLNSLVDKTSWIPSSVAEALGIVPLQYVFVMTFTLDDGTGVLEAYLMDSDKFFQIPASEVLMDDDLQKSVDMIMDMFCPPGIKIDAYPWLECFIKSYNVTNGTDNQICYQIFDTTVAEDVI DIP protein Q9NUX5-1 original sequence version: 60 DIP protein Q9NUX5 original sequence version: 89 DIP protein Q9NUX5 original sequence version: 112 DIP protein Q9NUX5 original sequence version: 137 stn1_human CST complex subunit STN1 STN1 OBFC1 Oligonucleotide/oligosaccharide-binding fold-containing protein 1 Suppressor of cdc thirteen homolog protein protein human Homo sapiens Human MQPGSSRCEEETPSLLWGLDPVFLAFAKLYIRDILDMKESRQVPGVFLYNGHPIKQVDVLGTVIGVRERDAFYSYGVDDSTGVINCICWKKLNTESVSAAPSAARELSLTSQLKKLQETIEQKTKIEIGDTIRVRGSIRTYREEREIHATTYYKVDDPVWNIQIARMLELPTIYRKVYDQPFHSSALEKEEALSNPGALDLPSLTSLLSEKAKEFLMENRVQSFYQQELEMVESLLSLANQPVIHSASSDQVNFKKDTTSKAIHSIFKNAIQLLQEKGLVFQKDDGFDNLYYVTREDKDLHRKIHRIIQQDCQKPNHMEKGCHFLHILACARLSIRPGLSEAVLQQVLELLEDQSDIVSTMEHYYTAF DIP protein Q9H668 original sequence version: 89 087E7EF75544A1F0 q2nkj3-1 CST complex subunit CTC1 CTC1 C17orf68 Conserved telomere maintenance component 1 HBV DNAPTP1-transactivated protein B protein protein human Homo sapiens Human MAAGRAQVPSSEQAWLEDAQVFIQKTLCPAVKEPNVQLTPLVIDCVKTVWLSQGRNQGSTLPLSYSFVSVQDLKTHQRLPCCSHLSWSSSAYQAWAQEAGPNGNPLPREQLLLLGTLTDLSADLEQECRNGSLYVRDNTGVLSCELIDLDLSWLGHLFLFPRWSYLPPARWNSSGEGHLELWDAPVPVFPLTISPGPVTPIPVLYPESASCLLRLRNKLRGVQRNLAGSLVRLSALVKSKQKAYFILSLGRSHPAVTHVSIIVQVPAQLVWHRALRPGTAYVLTELRVSKIRGQRQHVWMTSQSSRLLLLKPECVQELELELEGPLLEADPKPLPMPSNSEDKKDPESLVRYSRLLSYSGAVTGVLNEPAGLYELDGQLGLCLAYQQFRGLRRVMRPGVCLQLQDVHLLQSVGGGTRRPVLAPCLRGAVLLQSFSRQKPGAHSSRQAYGASLYEQLVWERQLGLPLYLWATKALEELACKLCPHVLRHHQFLQHSSPGSPSLGLQLLAPTLDLLAPPGSPVRNAHNEILEEPHHCPLQKYTRLQTPSSFPTLATLKEEGQRKAWASFDPKALLPLPEASYLPSCQLNRRLAWSWLCLLPSAFCPAQVLLGVLVASSHKGCLQLRDQSGSLPCLLLAKHSQPLSDPRLIGCLVRAERFQLIVERDVRSSFPSWKELSMPGFIQKQQARVYVQFFLADALILPVPRPCLHSATPSTPQTDPTGPEGPHLGQSRLFLLCHKEALMKRNFCVPPGASPEVPKPALSFYVLGSWLGGTQRKEGTGWGLPEPQGNDDNDQKVHLIFFGSSVRWFEFLHPGQVYRLIAPGPATPMLFEKDGSSCISRRPLELAGCASCLTVQDNWTLELESSQDIQDVLDANKSLPESSLTDLLSDNFTDSLVSFSAEILSRTLCEPLVASLWMKLGNTGAMRRCVKLTVALETAECEFPPHLDVYIEDPHLPPSLGLLPGARVHFSQLEKRVSRSHNVYCCFRSSTYVQVLSFPPETTISIPLPHIYLAELLQGGQSPFQATASCHIVSVFSLQLFWVCAYCTSICRQGKCTRLGSTCPTQTAISQAIIRLLVEDGTAEAVVTCRNHHVAAALGLCPREWASLLDFVQVPGRVVLQFAGPGAQLESSARVDEPMTMFLWTLCTSPSVLRPIVLSFELERKPSKIVPLEPPRLQRFQCGELPFLTHVNPRLRLSCLSIRESEYSSSLGILASSC DIP protein Q2NKJ3-1 original sequence version: 50 stn1-tpp1-1 12 16 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 19 unspecified role unspecified role bait bait yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast direct interaction direct interaction ten1-ctc1-1 2 19 unspecified role unspecified role prey prey human Homo sapiens Human 20 unspecified role unspecified role prey prey human Homo sapiens Human 17 unspecified role unspecified role bait bait His-tag His-tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human association association ctc1-stn1-1 3 19 unspecified role unspecified role prey prey Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range human Homo sapiens Human 20 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human Homo sapiens Human physical association physical association stn1-ctc1-1 6 19 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged c-term range C-terminal range c-term range c-term range C-terminal range c-term range human Homo sapiens Human 20 unspecified role unspecified role prey prey V5-tag V5-tag v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human Homo sapiens Human physical association physical association ctc1-tpp1-1 1 16 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 20 unspecified role unspecified role bait bait Region 844-1217 Region 844-1217 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast direct interaction direct interaction ctc1-stn1-2 15 19 unspecified role unspecified role unspecified role unspecified role human Homo sapiens Human 20 unspecified role unspecified role unspecified role unspecified role human Homo sapiens Human 17 unspecified role unspecified role unspecified role unspecified role human Homo sapiens Human physical association physical association ctc1-tpp1-2 4 16 unspecified role unspecified role prey prey V5-tag V5-tag v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human Homo sapiens Human 20 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human Homo sapiens Human physical association physical association stn1-pot1-2 14 18 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 19 unspecified role unspecified role bait bait yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast direct interaction direct interaction ctc1-stn1-3 8 19 unspecified role unspecified role prey prey human Homo sapiens Human 20 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Region 844-1217 Region 844-1217 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human physical association physical association ten1-stn1-9 7 19 unspecified role unspecified role prey prey human Homo sapiens Human 17 unspecified role unspecified role bait bait His-tag His-tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human physical association physical association tpp1-ctc1-1 9 16 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human Homo sapiens Human 20 unspecified role unspecified role prey prey V5-tag V5-tag v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Region 1-701 Region 1-701 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain Region 844-1217 Region 844-1217 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human physical association physical association ctc1-stn1-4 10 19 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 20 unspecified role unspecified role bait bait Region 844-1217 Region 844-1217 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast direct interaction direct interaction pot1-tpp1-1 5 16 unspecified role unspecified role prey prey human Homo sapiens Human 18 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human physical association physical association stn1-tpp1-2 11 19 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged c-term range C-terminal range c-term range c-term range C-terminal range c-term range human Homo sapiens Human 16 unspecified role unspecified role prey prey V5-tag V5-tag v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human Homo sapiens Human physical association physical association ctc1-pot1-1 13 18 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 20 unspecified role unspecified role bait bait Region 844-1217 Region 844-1217 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast direct interaction direct interaction