DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Structure and allostery of the PKA RIIβ tetrameric holoenzyme. Structure and allostery of the PKA RIIβ tetrameric holoenzyme. Science (New York, N.Y.) 2012 imex curation Zhang P., Smith-Nguyen EV., Keshwani MM., Deal MS., Kornev AP., Taylor SS. Only protein-protein interactions in vitro In vitro x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Zhang P., Smith-Nguyen EV., Keshwani MM., Deal MS., Kornev AP., Taylor SS. DIP original experiment: DIP-268301X Science (New York, N.Y.) 2012 IMEx Structure and allostery of the PKA RIIβ tetrameric holoenzyme. Structure and allostery of the PKA RIIβ tetrameric holoenzyme. Structure and allostery of the PKA RIIβ tetrameric holoenzyme. Science (New York, N.Y.) 2012 imex curation Zhang P., Smith-Nguyen EV., Keshwani MM., Deal MS., Kornev AP., Taylor SS. Only protein-protein interactions in vitro In vitro saxs x ray scattering saxs predetermined predetermined participant predetermined Zhang P., Smith-Nguyen EV., Keshwani MM., Deal MS., Kornev AP., Taylor SS. DIP original experiment: DIP-268300X Science (New York, N.Y.) 2012 IMEx Structure and allostery of the PKA RIIβ tetrameric holoenzyme. Structure and allostery of the PKA RIIβ tetrameric holoenzyme. Structure and allostery of the PKA RIIβ tetrameric holoenzyme. Science (New York, N.Y.) 2012 imex curation Zhang P., Smith-Nguyen EV., Keshwani MM., Deal MS., Kornev AP., Taylor SS. Only protein-protein interactions in vitro In vitro molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Zhang P., Smith-Nguyen EV., Keshwani MM., Deal MS., Kornev AP., Taylor SS. DIP original experiment: DIP-268299X Science (New York, N.Y.) 2012 IMEx Structure and allostery of the PKA RIIβ tetrameric holoenzyme. kap3_mouse cAMP-dependent protein kinase type II-beta regulatory subunit Prkar2b protein protein mouse Mus musculus Mouse MSIEIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGAARFGHEGRTWGDAGAAAGGGIPSKGVNFAEEPMRSDSENGEEEEAAEAGAFNAPVINRFTRRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDIVEPTA DIP protein P31324 original sequence version: 140 DIP protein P31324 original sequence version: 139 DIP protein P31324 original sequence version: 144 DIP protein P31324 original sequence version: 98 24196C3037789827 kapca_mouse cAMP-dependent protein kinase catalytic subunit alpha Prkaca Pkaca protein protein mouse Mus musculus Mouse MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF DIP protein P05132 original sequence version: 185 DIP protein P05132 original sequence version: 186 DIP protein P05132-1 original sequence version: 145 DIP protein P05132-1 original sequence version: 193 DIP protein P05132-1 original sequence version: 199 DIP protein P05132 original sequence version: 163 DIP protein P05132 original sequence version: 192 DIP protein P05132-1 original sequence version: 197 DIP protein P05132-1 original sequence version: 149 02F85D66EB21A1FA prkaca-prkar2b-8 3 4 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli 5 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction prkaca-prkar2b-9 2 4 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli 5 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction prkaca-prkar2b-10 1 4 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli 5 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction