DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Nature 2012 imex curation Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. Only protein-protein interactions yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. DIP original experiment: DIP-254572X Nature 2012 IMEx Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Nature 2012 imex curation Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. Only protein-protein interactions in vitro In vitro methyltransferase as methyltransferase assay methyltransferase as weight autoradiogra molecular weight estimation by autoradiography weight autoradiogra Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. DIP original experiment: DIP-254565X Nature 2012 IMEx Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Nature 2012 imex curation Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. Only protein-protein interactions in vitro In vitro methyltransferase as methyltransferase assay methyltransferase as weight autoradiogra molecular weight estimation by autoradiography weight autoradiogra Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. DIP original experiment: DIP-254568X Nature 2012 IMEx Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Nature 2012 imex curation Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. DIP original experiment: DIP-254559X Nature 2012 IMEx Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Nature 2012 imex curation Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. Only protein-protein interactions in vitro In vitro pull down pull down predetermined predetermined participant predetermined Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. DIP original experiment: DIP-254574X Nature 2012 IMEx Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Nature 2012 imex curation Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. Only protein-protein interactions in vitro In vitro methyltransferase as methyltransferase assay methyltransferase as weight autoradiogra molecular weight estimation by autoradiography weight autoradiogra Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. DIP original experiment: DIP-254566X Nature 2012 IMEx Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Nature 2012 imex curation Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. Only protein-protein interactions in vitro In vitro methyltransferase as methyltransferase assay methyltransferase as weight autoradiogra molecular weight estimation by autoradiography weight autoradiogra Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. DIP original experiment: DIP-254569X Nature 2012 IMEx Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Nature 2012 imex curation Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. Only protein-protein interactions in vitro In vitro pull down pull down anti tag western anti tag western blot anti tag western Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. DIP original experiment: DIP-254577X Nature 2012 IMEx Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Nature 2012 imex curation Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. Only protein-protein interactions yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. DIP original experiment: DIP-254557X Nature 2012 IMEx Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Nature 2012 imex curation Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. Only protein-protein interactions in vitro In vitro pull down pull down anti tag western anti tag western blot anti tag western Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. DIP original experiment: DIP-254561X Nature 2012 IMEx Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Nature 2012 imex curation Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. Only protein-protein interactions in vitro In vitro pull down pull down western blot western blot Immuno blot Immuno blot Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. DIP original experiment: DIP-254562X Nature 2012 IMEx Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Nature 2012 imex curation Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. Only protein-protein interactions in vitro In vitro pull down pull down predetermined predetermined participant predetermined Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. DIP original experiment: DIP-254573X Nature 2012 IMEx Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Nature 2012 imex curation Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. Only protein-protein interactions in vitro In vitro methyltransferase as methyltransferase assay methyltransferase as weight autoradiogra molecular weight estimation by autoradiography weight autoradiogra Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. DIP original experiment: DIP-254567X Nature 2012 IMEx Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Nature 2012 imex curation Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. Only protein-protein interactions in vitro In vitro pull down pull down predetermined predetermined participant predetermined Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. DIP original experiment: DIP-254563X Nature 2012 IMEx Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Nature 2012 imex curation Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. DIP original experiment: DIP-254571X Nature 2012 IMEx Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Nature 2012 imex curation Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. DIP original experiment: DIP-254558X Nature 2012 IMEx Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Nature 2012 imex curation Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. Only protein-protein interactions yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. DIP original experiment: DIP-254556X Nature 2012 IMEx Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Nature 2012 imex curation Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. Only protein-protein interactions in vitro In vitro methyltransferase as methyltransferase assay methyltransferase as weight autoradiogra molecular weight estimation by autoradiography weight autoradiogra Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. DIP original experiment: DIP-254570X Nature 2012 IMEx Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Nature 2012 imex curation Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. Only protein-protein interactions in vitro In vitro pull down pull down anti tag western anti tag western blot anti tag western Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. DIP original experiment: DIP-254576X Nature 2012 IMEx Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Nature 2012 imex curation Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. Only protein-protein interactions in vitro In vitro pull down pull down predetermined predetermined participant predetermined Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. DIP original experiment: DIP-254575X Nature 2012 IMEx Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Nature 2012 imex curation Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. Only protein-protein interactions in vitro In vitro pull down pull down anti tag western anti tag western blot anti tag western Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. DIP original experiment: DIP-254578X Nature 2012 IMEx Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Nature 2012 imex curation Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. Only protein-protein interactions human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. DIP original experiment: DIP-254564X Nature 2012 IMEx Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Nature 2012 imex curation Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. Only protein-protein interactions in vitro In vitro pull down pull down western blot western blot Immuno blot Immuno blot Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. DIP original experiment: DIP-254560X Nature 2012 IMEx Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Nature 2012 imex curation Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. Only protein-protein interactions in vitro In vitro methyltransferase as methyltransferase assay methyltransferase as weight autoradiogra molecular weight estimation by autoradiography weight autoradiogra Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. DIP original experiment: DIP-254579X Nature 2012 IMEx Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Nature 2012 imex curation Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. Only protein-protein interactions in vitro In vitro methyltransferase as methyltransferase assay methyltransferase as predetermined predetermined participant predetermined Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. DIP original experiment: DIP-254581X Nature 2012 IMEx Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Nature 2012 imex curation Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. Only protein-protein interactions in vitro In vitro methyltransferase as methyltransferase assay methyltransferase as predetermined predetermined participant predetermined Zhang L., Ding X., Cui J., Xu H., Chen J., Gong YN., Hu L., Zhou Y., Ge J., Lu Q., Liu L., Chen S., Shao F. DIP original experiment: DIP-254580X Nature 2012 IMEx Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. tab2_human TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TAB2 KIAA0733 MAP3K7IP2 TAK1-binding protein 2 Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 TGF-beta-activated kinase 1-binding protein 2 protein protein human Homo sapiens Human MAQGSHQIDFQVLHDLRQKFPEVPEVVVSRCMLQNNNNLDACCAVLSQESTRYLYGEGDLNFSDDSGISGLRNHMTSLNLDLQSQNIYHHGREGSRMNGSRTLTHSISDGQLQGGQSNSELFQQEPQTAPAQVPQGFNVFGMSSSSGASNSAPHLGFHLGSKGTSSLSQQTPRFNPIMVTLAPNIQTGRNTPTSLHIHGVPPPVLNSPQGNSIYIRPYITTPGGTTRQTQQHSGWVSQFNPMNPQQVYQPSQPGPWTTCPASNPLSHTSSQQPNQQGHQTSHVYMPISSPTTSQPPTIHSSGSSQSSAHSQYNIQNISTGPRKNQIEIKLEPPQRNNSSKLRSSGPRTSSTSSSVNSQTLNRNQPTVYIAASPPNTDELMSRSQPKVYISANAATGDEQVMRNQPTLFISTNSGASAASRNMSGQVSMGPAFIHHHPPKSRAIGNNSATSPRVVVTQPNTKYTFKITVSPNKPPAVSPGVVSPTFELTNLLNHPDHYVETENIQHLTDPTLAHVDRISETRKLSMGSDDAAYTQALLVHQKARMERLQRELEIQKKKLDKLKSEVNEMENNLTRRRLKRSNSISQIPSLEEMQQLRSCNRQLQIDIDCLTKEIDLFQARGPHFNPSAIHNFYDNIGFVGPVPPKPKDQRSIIKTPKTQDTEDDEGAQWNCTACTFLNHPALIRCEQCEMPRHF DIP protein Q9NYJ8 original sequence version: 61 DIP protein Q9NYJ8 original sequence version: 107 DIP protein Q9NYJ8 original sequence version: 99 DIP protein Q9NYJ8 original sequence version: 100 DIP protein Q9NYJ8-1 original sequence version: 100 47BB8709320084D7 shrpn_human Sharpin SHARPIN SIPL1 Shank-associated RH domain-interacting protein Shank-interacting protein-like 1 PSEC0216 protein protein human Homo sapiens Human MAPPAGGAAAAASDLGSAAVLLAVHAAVRPLGAGPDAEAQLRRLQLSADPERPGRFRLELLGAGPGAVNLEWPLESVSYTIRGPTQHELQPPPGGPGTLSLHFLNPQEAQRWAVLVRGATVEGQNGSKSNSPPALGPEACPVSLPSPPEASTLKGPPPEADLPRSPGNLTEREELAGSLARAIAGGDEKGAAQVAAVLAQHRVALSVQLQEACFPPGPIRLQVTLEDAASAASAASSAHVALQVHPHCTVAALQEQVFSELGFPPAVQRWVIGRCLCVPERSLASYGVRQDGDPAFLYLLSAPREAPATGPSPQHPQKMDGELGRLFPPSLGLPPGPQPAASSLPSPLQPSWSCPSCTFINAPDRPGCEMCSTQRPCTWDPLAAAST DIP protein Q9H0F6 original sequence version: 80 DIP protein Q9H0F6 original sequence version: 89 DIP protein Q9H0F6-1 original sequence version: 68 DIP protein Q9H0F6 original sequence version: 68 DIP protein Q9H0F6-1 original sequence version: 72 DIP protein Q9H0F6 original sequence version: 91 33EE4BF66936AB60 rnf31_human E3 ubiquitin-protein ligase RNF31 Zinc in-between-RING-finger ubiquitin-associated domain protein RNF31 ZIBRA HOIL-1-interacting protein RING finger protein 31 RING-type E3 ubiquitin transferase RNF31 protein protein human Homo sapiens Human MPGEEEERAFLVAREELASALRRDSGQAFSLEQLRPLLASSLPLAARYLQLDAARLVRCNAHGEPRNYLNTLSTALNILEKYGRNLLSPQRPRYWRGVKFNNPVFRSTVDAVQGGRDVLRLYGYTEEQPDGLSFPEGQEEPDEHQVATVTLEVLLLRTELSLLLQNTHPRQQALEQLLEDKVEDDMLQLSEFDPLLREIAPGPLTTPSVPGSTPGPCFLCGSAPGTLHCPSCKQALCPACDHLFHGHPSRAHHLRQTLPGVLQGTHLSPSLPASAQPRPQSTSLLALGDSSLSSPNPASAHLPWHCAACAMLNEPWAVLCVACDRPRGCKGLGLGTEGPQGTGGLEPDLARGRWACQSCTFENEAAAVLCSICERPRLAQPPSLVVDSRDAGICLQPLQQGDALLASAQSQVWYCIHCTFCNSSPGWVCVMCNRTSSPIPAQHAPRPYASSLEKGPPKPGPPRRLSAPLPSSCGDPEKQRQDKMREEGLQLVSMIREGEAAGACPEEIFSALQYSGTEVPLQWLRSELPYVLEMVAELAGQQDPGLGAFSCQEARRAWLDRHGNLDEAVEECVRTRRRKVQELQSLGFGPEEGSLQALFQHGGDVSRALTELQRQRLEPFRQRLWDSGPEPTPSWDGPDKQSLVRRLLAVYALPSWGRAELALSLLQETPRNYELGDVVEAVRHSQDRAFLRRLLAQECAVCGWALPHNRMQALTSCECTICPDCFRQHFTIALKEKHITDMVCPACGRPDLTDDTQLLSYFSTLDIQLRESLEPDAYALFHKKLTEGVLMRDPKFLWCAQCSFGFIYEREQLEATCPQCHQTFCVRCKRQWEEQHRGRSCEDFQNWKRMNDPEYQAQGLAMYLQENGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNKCPEPNCRVKKSLHGHHPRDCLFYLRDWTALRLQKLLQDNNVMFNTEPPAGARAVPGGGCRVIEQKEVPNGLRDEACGKETPAGYAGLCQAHYKEYLVSLINAHSLDPATLYEVEELETATERYLHVRPQPLAGEDPPAYQARLLQKLTEEVPLGQSIPRRRK DIP protein Q96EP0 original sequence version: 118 DIP protein Q96EP0-1 original sequence version: 145 DIP protein Q96EP0-1 original sequence version: 91 DIP protein Q96EP0 original sequence version: 91 DIP protein Q96EP0-1 original sequence version: 98 DIP protein Q96EP0-1 original sequence version: 120 CFAD183A14F764BA hoil1_human RanBP-type and C3HC4-type zinc finger-containing protein 1 RBCK1 C20orf18 RNF54 UBCE7IP3 XAP3 XAP4 Ubiquitin-conjugating enzyme 7-interacting protein 3 Hepatitis B virus X-associated protein 4 HBV-associated factor 4 RING finger protein 54 Heme-oxidized IRP2 ubiquitin ligase 1 RING-type E3 ubiquitin transferase HOIL-1 protein protein human Homo sapiens Human MDEKTKKAEEMALSLTRAVAGGDEQVAMKCAIWLAEQRVPLSVQLKPEVSPTQDIRLWVSVEDAQMHTVTIWLTVRPDMTVASLKDMVFLDYGFPPVLQQWVIGQRLARDQETLHSHGVRQNGDSAYLYLLSARNTSLNPQELQRERQLRMLEDLGFKDLTLQPRGPLEPGPPKPGVPQEPGRGQPDAVPEPPPVGWQCPGCTFINKPTRPGCEMCCRARPEAYQVPASYQPDEEERARLAGEEEALRQYQQRKQQQQEGNYLQHVQLDQRSLVLNTEPAECPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQEAEVSCPFIDNTYSCSGKLLEREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFEDDVNEFTCPVCFHVNCLLCKAIHEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQGEAMRCPQCQIVVQKKDGCDWIRCTVCHTEICWVTKGPRWGPGGPGDTSGGCRCRVNGIPCHPSCQNCH DIP protein Q9BYM8 original sequence version: 114 DIP protein Q9BYM8 original sequence version: 124 DIP protein Q9BYM8-1 original sequence version: 102 DIP protein Q9BYM8 original sequence version: 102 DIP protein Q9BYM8-1 original sequence version: 107 DIP protein Q9BYM8-1 original sequence version: 126 C6EF957B1F152FF2 m3k7_human Mitogen-activated protein kinase kinase kinase 7 MAP3K7 TAK1 Transforming growth factor-beta-activated kinase 1 protein protein human Homo sapiens Human MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAFIVELRQLSRVNHPNIVKLYGACLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTACDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPGADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDTIKRLESKLLKNQAKQQSESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIAATTAYSKPKRGHRKTASFGNILDVPEIVISGNGQPRRRSIQDLTVTGTEPGQVSSRSSSPSVRMITTSGPTSEKPTRSHPWTPDDSTDTNGSDNSIPMAYLTLDHQLQPLAPCPNSKESMAVFEQHCKMAQEYMKVQTEIALLLQRKQELVAELDQDEKDQQNTSRLVQEHKKLLDENKSLSTYYQQCKKQLEVIRSQQQKRQGTS DIP protein O43318 original sequence version: 145 DIP protein O43318 original sequence version: 138 DIP protein O43318 original sequence version: 131 3D8F8147CD174013 tab1_human TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TAB1 MAP3K7IP1 TGF-beta-activated kinase 1-binding protein 1 Mitogen-activated protein kinase kinase kinase 7-interacting protein 1 protein protein human Homo sapiens Human MAAQRRSLLQSEQQPSWTDDLPLCHLSGVGSASNRSYSADGKGTESHPPEDSWLKFRSENNCFLYGVFNGYDGNRVTNFVAQRLSAELLLGQLNAEHAEADVRRVLLQAFDVVERSFLESIDDALAEKASLQSQLPEGVPQHQLPPQYQKILERLKTLEREISGGAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGLQVTQLNVDHTTENEDELFRLSQLGLDAGKIKQVGIICGQESTRRIGDYKVKYGYTDIDLLSAAKSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLYKALEAAHGPGQANQEIAAMIDTEFAKQTSLDAVAQAVVDRVKRIHSDTFASGGERARFCPRHEDMTLLVRNFGYPLGEMSQPTPSPAPAAGGRVYPVSVPYSSAQSTSKTSVTLSLVMPSQGQMVNGAHSASTLDEATPTLTNQSPTLTLQSTNTHTQSSSSSSDGGLFRSRPAHSLPPGEDGRVEPYVDFAEFYRLWSVDHGEQSVVTAP DIP protein Q15750 original sequence version: 74 DIP protein Q15750 original sequence version: 110 DIP protein Q15750 original sequence version: 111 A45743288718983A ubiq_human UBIQ_HUMAN protein protein human Homo sapiens Human MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG nlee_eco27 Cysteine S-methyltransferase NleE E2348C_3232 nleE Effector protein NleE Non-LEE-encoded type III effector E protein protein eco27 Escherichia coli O127:H6 (strain E2348/69 / EPEC) MINPVTNTQGVSPINTKYAEHVVKNIYPKIKHDYFNESPNIYDKKYISGITRGVAELKQEEFVNEKARRFSYMKTMYSVCPEAFEPISRNEASTPEGSWLTVISGKRPMGQFSVDSLYNPDLHALCELPDICCKIFPKENNDFLYIVVVYRNDSPLGEQRANRFIELYNIKRDIMQELNYELPELKAVKSEMIIAREMGEIFSYMPGEIDSYMKYINNKLSKIE DIP protein B7UI22 original sequence version: 14 vps36_yeast Vacuolar protein-sorting-associated protein 36 VPS36 GRD12 VAC3 VPL11 YLR417W ESCRT-II complex subunit VPS36 protein protein yeast Saccharomyces cerevisiae Baker's yeast MEYWHYVETTSSGQPLLREGEKDIFIDQSVGLYHGKSKILQRQRGRIFLTSQRIIYIDDAKPTQNSLGLELDDLAYVNYSSGFLTRSPRLILFFKDPSSKDELGKSAETASADVVSTWVCPICMVSNETQGEFTKDTLPTPICINCGVPADYELTKSSINCSNAIDPNANPQNQFGVNSENICPACTFANHPQIGNCEICGHRLPNASKVRSKLNRLNFHDSRVHIELEKNSLARNKSSHSALSSSSSTGSSTEFVQLSFRKSDGVLFSQATERALENILTEKNKHIFNQNVVSVNGVDMRKGASSHEYNNEVPFIETKLSRIGISSLEKSRENQLLNNDILFNNALTDLNKLMSLATSIERLYKNSNITMKTKTLNLQDESTVNEPKTRRPLLILDREKFLNKELFLDEIAREIYEFTLSEFKDLNSDTNYMIITLVDLYAMYNKSMRIGTGLISPMEMREACERFEHLGLNELKLVKVNKRILCVTSEKFDVVKEKLVDLIGDNPGSDLLRLTQILSSNNSKSNWTLGILMEVLQNCVDEGDLLIDKQLSGIYYYKNSYWPSHI 60DDD4EA3A620409 60DDD4EA3A620409 q8n5c8-1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 TAB3 MAP3K7IP3 Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 NF-kappa-B-activating protein 1 TAK1-binding protein 3 TGF-beta-activated kinase 1-binding protein 3 Tab3a protein protein human Homo sapiens Human MAQSSPQLDIQVLHDLRQRFPEIPEGVVSQCMLQNNNNLEACCRALSQESSKYLYMEYHSPDDNRMNRNRLLHINLGIHSPSSYHPGDGAQLNGGRTLVHSSSDGHIDPQHAAGKQLICLVQEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPPPPPSYMHIPRYSTNPITVTVSQNLPSGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSSGRQTPQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHSVAYLPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSPRNQHSLYTATTPPSSSPSRGISSQPKPPFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTTVFKITVGRATTENLLNLVDQEERSAAPEPIQPISVIPGSGGEKGSHKYQRSSSSGSDDYAYTQALLLHQRARMERLAKQLKLEKEELERLKSEVNGMEHDLMQRRLRRVSCTTAIPTPEEMTRLRSMNRQLQINVDCTLKEVDLLQSRGNFDPKAMNNFYDNIEPGPVVPPKPSKKDSSDPCTIERKARRISVTSKVQADIHDTQAAAADEHRTGSTQSPRTQPRDEDYEGAPWNCDSCTFLNHPALNRCEQCEMPRYT DIP protein Q8N5C8-1 original sequence version: 78 2FAC686AE5CDB1E5 map3k7-tab1-2 17 32 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 31 unspecified role unspecified role bait bait yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association rnf31-ub-3 12 29 unspecified role unspecified role bait bait NZF1 domain Region 350-379 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecolx Escherichia coli 33 unspecified role unspecified role prey prey direct interaction direct interaction map3k7-tab1-3 22 27 unspecified role unspecified role prey prey human Homo sapiens Human 32 unspecified role unspecified role prey prey human Homo sapiens Human 31 unspecified role unspecified role bait bait human Homo sapiens Human association association b7ui22_eco27-tab3-1 9 36 unspecified role unspecified role prey prey Region 1-683 Region 1-683 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 34 unspecified role unspecified role bait bait yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association b7ui22_eco27-tab2-1 25 27 enzyme target enzyme target substrate substrate unspecified role unspecified role NZF domain Region 665-693 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain metC673 metC673 mecys methylated cysteine MeCys modified residue ms mass detection of residue modification modified residue ms certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 34 enzyme enzyme unspecified role unspecified role ecolx Escherichia coli methylation methylation reaction methylation rnf31-sharpin-8 1 28 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 29 unspecified role unspecified role bait bait yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association b7ui22_eco27-tab3-2 2 36 enzyme target enzyme target substrate substrate unspecified role unspecified role NZF domain Region 684-712 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 34 enzyme enzyme unspecified role unspecified role region Δ209-214 required to bind necessary binding region required to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain This feature has been corrected as a result of our quality control procedures. The original label was 'Δ209-214'. ecolx Escherichia coli methylation methylation reaction methylation tab3-b7ui22_eco27-1 16 36 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human Homo sapiens Human 34 unspecified role unspecified role prey prey GFP-tag GFP-tag gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human physical association physical association rbck1-ub-3 20 30 unspecified role unspecified role bait bait NZF domain Region 193-222 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecolx Escherichia coli 33 unspecified role unspecified role prey prey direct interaction direct interaction b7ui22_eco27-tab2-2 6 27 enzyme target enzyme target substrate substrate unspecified role unspecified role NZF domain Region 665-693 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 34 enzyme enzyme unspecified role unspecified role region Δ209-214 required to bind necessary binding region required to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain This feature has been corrected as a result of our quality control procedures. The original label was 'Δ209-214'. ecolx Escherichia coli methylation methylation reaction methylation tab2-b7ui22_eco27-1 4 27 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human 34 unspecified role unspecified role prey prey GFP-tag GFP-tag gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human physical association physical association b7ui22_eco27-tab2-3 3 27 enzyme target enzyme target substrate substrate unspecified role unspecified role human Homo sapiens Human 34 enzyme enzyme unspecified role unspecified role region Δ209-214 required to bind necessary binding region required to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain This feature has been corrected as a result of our quality control procedures. The original label was 'Δ209-214'. ecolx Escherichia coli methylation methylation reaction methylation sharpin-ub-3 5 28 unspecified role unspecified role bait bait NZF domain Region 340-387 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecolx Escherichia coli 33 unspecified role unspecified role prey prey direct interaction direct interaction b7ui22_eco27-tab3-3 13 36 enzyme target enzyme target substrate substrate unspecified role unspecified role human Homo sapiens Human 34 enzyme enzyme unspecified role unspecified role region Δ209-214 required to bind necessary binding region required to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain This feature has been corrected as a result of our quality control procedures. The original label was 'Δ209-214'. ecolx Escherichia coli methylation methylation reaction methylation ub-tab3-1 23 33 unspecified role unspecified role bait bait SBP-tag SBP-tag sbp sbp n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal 36 unspecified role unspecified role prey prey Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human Homo sapiens Human physical association physical association b7ui22_eco27-tab3-4 7 36 enzyme target enzyme target substrate substrate unspecified role unspecified role NZF domain Region 684-712 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain Q8N5C8-1:p.Cys706Ser C706S mutation disrupting mutation disrupting interaction mutation disrupting substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain C S This feature has been corrected as a result of our quality control procedures. The original label was 'C706S'. Wed May 02 15:30:34 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'cys706ser' Tue Jun 30 16:30:50 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Cys706Ser' Q8N5C8-1:p.Cys703Ser C703S mutation disrupting mutation disrupting interaction mutation disrupting substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain C S This feature has been corrected as a result of our quality control procedures. The original label was 'C703S'. Wed May 02 15:25:39 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'cys703ser' Tue Jun 30 18:49:26 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Cys703Ser' Q8N5C8-1:p.Cys689Ser C689S mutation disrupting mutation disrupting interaction mutation disrupting substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain C S This feature has been corrected as a result of our quality control procedures. The original label was 'C689S'. Wed May 02 20:25:23 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'cys689ser' Tue Jun 30 19:29:19 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Cys689Ser' Q8N5C8-1:p.Cys692Met C692M/L mutation disrupting rate mutation disrupting interaction rate mutation disrupting rate substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain C M Wed May 02 17:48:33 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'cys692met' Tue Jun 30 17:12:19 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Cys692Met' Q8N5C8-1:p.Cys692Leu mutation disrupting rate mutation disrupting interaction rate mutation disrupting rate certain certain sequence position certain certain certain sequence position certain C L Wed May 02 17:18:04 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'cys692leu' Tue Jun 30 17:53:37 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Cys692Leu' ecolx Escherichia coli 34 enzyme enzyme unspecified role unspecified role ecolx Escherichia coli methylation methylation reaction methylation ub-sharpin-3 8 28 unspecified role unspecified role prey prey Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human 33 unspecified role unspecified role bait bait physical association physical association ub-tab2-1 10 27 unspecified role unspecified role prey prey Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human 33 unspecified role unspecified role bait bait SBP-tag SBP-tag sbp sbp n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal physical association physical association ub-rnf31-2 19 29 unspecified role unspecified role prey prey Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human 33 unspecified role unspecified role bait bait physical association physical association tab3-ub-1 11 33 unspecified role unspecified role prey prey 36 unspecified role unspecified role bait bait GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined NZF domain Region 684-712 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain Q8N5C8-1:p.Cys692Met C692M/L mutation disrupting rate mutation disrupting interaction rate mutation disrupting rate substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain C M Wed May 02 18:13:18 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'cys692met' Tue Jun 30 16:58:41 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Cys692Met' Q8N5C8-1:p.Cys692Leu mutation disrupting rate mutation disrupting interaction rate mutation disrupting rate certain certain sequence position certain certain certain sequence position certain C L Wed May 02 15:53:54 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'cys692leu' Tue Jun 30 19:30:14 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Cys692Leu' ecolx Escherichia coli direct interaction direct interaction b7ui22_eco27-vps36-1 24 35 enzyme target enzyme target substrate substrate unspecified role unspecified role NZF domain Region 178-206 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 34 enzyme enzyme unspecified role unspecified role ecolx Escherichia coli methylation methylation reaction methylation tab2-ub-1 14 27 unspecified role unspecified role bait bait Q9NYJ8:p.Cys673Leu mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength certain certain sequence position certain certain certain sequence position certain C L Wed May 02 18:11:40 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'cys673leu' Tue Jun 30 15:36:28 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Cys673Leu' GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range NZF domain Region 665-693 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain Q9NYJ8:p.Cys673Met C673M/L mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain C M Wed May 02 18:43:58 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'cys673met' Tue Jun 30 17:59:14 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Cys673Met' ecolx Escherichia coli 33 unspecified role unspecified role prey prey direct interaction direct interaction b7ui22_eco27-tab3-5 26 36 enzyme target enzyme target substrate substrate unspecified role unspecified role NZF domain Region 684-712 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain metC692 metC692 mecys methylated cysteine MeCys modified residue ms mass detection of residue modification modified residue ms certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 34 enzyme enzyme unspecified role unspecified role ecolx Escherichia coli methylation methylation reaction methylation b7ui22_eco27-tab2-4 18 27 enzyme target enzyme target substrate substrate unspecified role unspecified role Q9NYJ8:p.Cys673Leu mutation disrupting rate mutation disrupting interaction rate mutation disrupting rate certain certain sequence position certain certain certain sequence position certain C L Wed May 02 16:18:14 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'cys673leu' Tue Jun 30 17:10:36 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Cys673Leu' NZF domain Region 665-693 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain Q9NYJ8:p.Cys673Met C673M/L mutation disrupting rate mutation disrupting interaction rate mutation disrupting rate substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain C M Wed May 02 15:04:31 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'cys673met' Tue Jun 30 20:04:51 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Cys673Met' Q9NYJ8:p.Cys687Ser C687S mutation disrupting mutation disrupting interaction mutation disrupting substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain C S This feature has been corrected as a result of our quality control procedures. The original label was 'C687S'. Wed May 02 14:32:51 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'cys687ser' Tue Jun 30 15:37:50 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Cys687Ser' Q9NYJ8:p.Cys684Ser C684S mutation disrupting mutation disrupting interaction mutation disrupting substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain C S This feature has been corrected as a result of our quality control procedures. The original label was 'C684S'. Wed May 02 19:58:52 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'cys684ser' Tue Jun 30 17:35:18 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Cys684Ser' Q9NYJ8:p.Cys670Ser C670S mutation disrupting mutation disrupting interaction mutation disrupting substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain C S This feature has been corrected as a result of our quality control procedures. The original label was 'C670S'. Wed May 02 14:46:02 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'cys670ser' Tue Jun 30 16:53:02 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Cys670Ser' ecolx Escherichia coli 34 enzyme enzyme unspecified role unspecified role ecolx Escherichia coli methylation methylation reaction methylation ub-rbck1-3 21 30 unspecified role unspecified role prey prey Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human 33 unspecified role unspecified role bait bait physical association physical association tab3-b7ui22_eco27-2 15 36 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Region1-683 Region1-683 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human 34 unspecified role unspecified role prey prey EGFP-tag EGFP-tag egfp tag enhanced green fluorescent protein tag enhanced green fluorescent protein EGFP enhanced green fluorescent protein EGFP egfp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human physical association physical association