DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure (London, England : 1993) 2011 imex curation Bolanos-Garcia VM., Lischetti T., Matak-Vinković D., Cota E., Simpson PJ., Chirgadze DY., Spring DR., Robinson CV., Nilsson J., Blundell TL. Only protein-protein interactions yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Bolanos-Garcia VM., Lischetti T., Matak-Vinković D., Cota E., Simpson PJ., Chirgadze DY., Spring DR., Robinson CV., Nilsson J., Blundell TL. DIP original experiment: DIP-252378X Structure (London, England : 1993) 2011 IMEx Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure (London, England : 1993) 2011 imex curation Bolanos-Garcia VM., Lischetti T., Matak-Vinković D., Cota E., Simpson PJ., Chirgadze DY., Spring DR., Robinson CV., Nilsson J., Blundell TL. Only protein-protein interactions in vitro In vitro itc isothermal titration calorimetry ITC ITC itc predetermined predetermined participant predetermined Bolanos-Garcia VM., Lischetti T., Matak-Vinković D., Cota E., Simpson PJ., Chirgadze DY., Spring DR., Robinson CV., Nilsson J., Blundell TL. DIP original experiment: DIP-252383X Structure (London, England : 1993) 2011 IMEx Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure (London, England : 1993) 2011 imex curation Bolanos-Garcia VM., Lischetti T., Matak-Vinković D., Cota E., Simpson PJ., Chirgadze DY., Spring DR., Robinson CV., Nilsson J., Blundell TL. Only protein-protein interactions yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Bolanos-Garcia VM., Lischetti T., Matak-Vinković D., Cota E., Simpson PJ., Chirgadze DY., Spring DR., Robinson CV., Nilsson J., Blundell TL. DIP original experiment: DIP-252379X Structure (London, England : 1993) 2011 IMEx Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure (London, England : 1993) 2011 imex curation Bolanos-Garcia VM., Lischetti T., Matak-Vinković D., Cota E., Simpson PJ., Chirgadze DY., Spring DR., Robinson CV., Nilsson J., Blundell TL. Only protein-protein interactions in vitro In vitro ms of complexes mass spectrometry studies of complexes ms of complexes predetermined predetermined participant predetermined Bolanos-Garcia VM., Lischetti T., Matak-Vinković D., Cota E., Simpson PJ., Chirgadze DY., Spring DR., Robinson CV., Nilsson J., Blundell TL. DIP original experiment: DIP-252382X Structure (London, England : 1993) 2011 IMEx Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure (London, England : 1993) 2011 imex curation Bolanos-Garcia VM., Lischetti T., Matak-Vinković D., Cota E., Simpson PJ., Chirgadze DY., Spring DR., Robinson CV., Nilsson J., Blundell TL. Only protein-protein interactions in vitro In vitro molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Bolanos-Garcia VM., Lischetti T., Matak-Vinković D., Cota E., Simpson PJ., Chirgadze DY., Spring DR., Robinson CV., Nilsson J., Blundell TL. DIP original experiment: DIP-252386X Structure (London, England : 1993) 2011 IMEx Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure (London, England : 1993) 2011 imex curation Bolanos-Garcia VM., Lischetti T., Matak-Vinković D., Cota E., Simpson PJ., Chirgadze DY., Spring DR., Robinson CV., Nilsson J., Blundell TL. Only protein-protein interactions in vitro In vitro fluorescence spectr classical fluorescence spectroscopy fluorescence spectr predetermined predetermined participant predetermined Bolanos-Garcia VM., Lischetti T., Matak-Vinković D., Cota E., Simpson PJ., Chirgadze DY., Spring DR., Robinson CV., Nilsson J., Blundell TL. DIP original experiment: DIP-252390X Structure (London, England : 1993) 2011 IMEx Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure (London, England : 1993) 2011 imex curation Bolanos-Garcia VM., Lischetti T., Matak-Vinković D., Cota E., Simpson PJ., Chirgadze DY., Spring DR., Robinson CV., Nilsson J., Blundell TL. Only protein-protein interactions in vitro In vitro molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Bolanos-Garcia VM., Lischetti T., Matak-Vinković D., Cota E., Simpson PJ., Chirgadze DY., Spring DR., Robinson CV., Nilsson J., Blundell TL. DIP original experiment: DIP-252381X Structure (London, England : 1993) 2011 IMEx Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure (London, England : 1993) 2011 imex curation Bolanos-Garcia VM., Lischetti T., Matak-Vinković D., Cota E., Simpson PJ., Chirgadze DY., Spring DR., Robinson CV., Nilsson J., Blundell TL. Only protein-protein interactions yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Bolanos-Garcia VM., Lischetti T., Matak-Vinković D., Cota E., Simpson PJ., Chirgadze DY., Spring DR., Robinson CV., Nilsson J., Blundell TL. DIP original experiment: DIP-252380X Structure (London, England : 1993) 2011 IMEx Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure (London, England : 1993) 2011 imex curation Bolanos-Garcia VM., Lischetti T., Matak-Vinković D., Cota E., Simpson PJ., Chirgadze DY., Spring DR., Robinson CV., Nilsson J., Blundell TL. Only protein-protein interactions in vitro In vitro nmr nuclear magnetic resonance NMR NMR nmr predetermined predetermined participant predetermined Bolanos-Garcia VM., Lischetti T., Matak-Vinković D., Cota E., Simpson PJ., Chirgadze DY., Spring DR., Robinson CV., Nilsson J., Blundell TL. DIP original experiment: DIP-252384X Structure (London, England : 1993) 2011 IMEx Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure (London, England : 1993) 2011 imex curation Bolanos-Garcia VM., Lischetti T., Matak-Vinković D., Cota E., Simpson PJ., Chirgadze DY., Spring DR., Robinson CV., Nilsson J., Blundell TL. Only protein-protein interactions in vitro In vitro ms of complexes mass spectrometry studies of complexes ms of complexes predetermined predetermined participant predetermined Bolanos-Garcia VM., Lischetti T., Matak-Vinković D., Cota E., Simpson PJ., Chirgadze DY., Spring DR., Robinson CV., Nilsson J., Blundell TL. DIP original experiment: DIP-252387X Structure (London, England : 1993) 2011 IMEx Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure (London, England : 1993) 2011 imex curation Bolanos-Garcia VM., Lischetti T., Matak-Vinković D., Cota E., Simpson PJ., Chirgadze DY., Spring DR., Robinson CV., Nilsson J., Blundell TL. Only protein-protein interactions in vitro In vitro cd circular dichroism CD CD cd predetermined predetermined participant predetermined Bolanos-Garcia VM., Lischetti T., Matak-Vinković D., Cota E., Simpson PJ., Chirgadze DY., Spring DR., Robinson CV., Nilsson J., Blundell TL. DIP original experiment: DIP-252385X Structure (London, England : 1993) 2011 IMEx Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure (London, England : 1993) 2011 imex curation Bolanos-Garcia VM., Lischetti T., Matak-Vinković D., Cota E., Simpson PJ., Chirgadze DY., Spring DR., Robinson CV., Nilsson J., Blundell TL. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Bolanos-Garcia VM., Lischetti T., Matak-Vinković D., Cota E., Simpson PJ., Chirgadze DY., Spring DR., Robinson CV., Nilsson J., Blundell TL. DIP original experiment: DIP-252389X Structure (London, England : 1993) 2011 IMEx Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. Structure (London, England : 1993) 2011 imex curation Bolanos-Garcia VM., Lischetti T., Matak-Vinković D., Cota E., Simpson PJ., Chirgadze DY., Spring DR., Robinson CV., Nilsson J., Blundell TL. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Bolanos-Garcia VM., Lischetti T., Matak-Vinković D., Cota E., Simpson PJ., Chirgadze DY., Spring DR., Robinson CV., Nilsson J., Blundell TL. DIP original experiment: DIP-252388X Structure (London, England : 1993) 2011 IMEx Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site. bub1b_human Mitotic checkpoint serine/threonine-protein kinase BUB1 beta MAD3/BUB1-related protein kinase Mitotic checkpoint kinase MAD3L SSK1 BUB1B BUBR1 MAD3L Protein SSK1 protein protein human Homo sapiens Human MAAVKKEGGALSEAMSLEGDEWELSKENVQPLRQGRIMSTLQGALAQESACNNTLQQQKRAFEYEIRFYTGNDPLDVWDRYISWTEQNYPQGGKESNMSTLLERAVEALQGEKRYYSDPRFLNLWLKLGRLCNEPLDMYSYLHNQGIGVSLAQFYISWAEEYEARENFRKADAIFQEGIQQKAEPLERLQSQHRQFQARVSRQTLLALEKEEEEEVFESSVPQRSTLAELKSKGKKTARAPIIRVGGALKAPSQNRGLQNPFPQQMQNNSRITVFDENADEASTAELSKPTVQPWIAPPMPRAKENELQAGPWNTGRSLEHRPRGNTASLIAVPAVLPSFTPYVEETARQPVMTPCKIEPSINHILSTRKPGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQIASESQKIPGMTLSSSVCQVNCCARETSLAENIWQEQPHSKGPSVPFSIFDEFLLSEKKNKSPPADPPRVLAQRRPLAVLKTSESITSNEDVSPDVCDEFTGIEPLSEDAIITGFRNVTICPNPEDTCDFARAARFVSTPFHEIMSLKDLPSDPERLLPEEDLDVKTSEDQQTACGTIYSQTLSIKKLSPIIEDSREATHSSGFSGSSASVASTSSIKCLQIPEKLELTNETSENPTQSPWCSQYRRQLLKSLPELSASAELCIEDRPMPKLEIEKEIELGNEDYCIKREYLICEDYKLFWVAPRNSAELTVIKVSSQPVPWDFYINLKLKERLNEDFDHFCSCYQYQDGCIVWHQYINCFTLQDLLQHSEYITHEITVLIIYNLLTIVEMLHKAEIVHGDLSPRCLILRNRIHDPYDCNKNNQALKIVDFSYSVDLRVQLDVFTLSGFRTVQILEGQKILANCSSPYQVDLFGIADLAHLLLFKEHLQVFWDGSFWKLSQNISELKDGELWNKFFVRILNANDEATVSVLGELAAEMNGVFDTTFQSHLNKALWKVGKLTSPGALLFQ DIP protein O60566 original sequence version: 106 DIP protein O60566 original sequence version: 130 DIP protein O60566-1 original sequence version: 119 DIP protein O60566-1 original sequence version: 154 DIP protein O60566 original sequence version: 154 F7871103A56E6B46 md2l1_human Mitotic spindle assembly checkpoint protein MAD2A MAD2L1 MAD2 Mitotic arrest deficient 2-like protein 1 protein protein human Homo sapiens Human MALQLSREQGITLRGSAEIVAEFFSFGINSILYQRGIYPSETFTRVQKYGLTLLVTTDLELIKYLNNVVEQLKDWLYKCSVQKLVVVISNIESGEVLERWQFDIECDKTAKDDSAPREKSQKAIQDEIRSVIRQITATVTFLPLLEVSCSFDLLIYTDKDLVVPEKWEESGPQFITNSEEVRLRSFTTTIHKVNSMVAYKIPVND DIP protein Q13257 original sequence version: 133 DIP protein Q13257 original sequence version: 78 DIP protein Q13257 original sequence version: 105 DIP protein Q13257 original sequence version: 120 DIP protein Q13257 original sequence version: 127 DIP protein Q13257 original sequence version: 116 DIP protein Q13257 original sequence version: 150 DIP protein Q13257 original sequence version: 156 DIP protein Q13257 original sequence version: 134 B8DCBF0043836764 q8ng31-2 Kinetochore scaffold 1 KNL1 ALL1-fused gene from chromosome 15q14 protein Bub-linking kinetochore protein CASC5 Cancer susceptibility candidate gene 5 protein Cancer/testis antigen 29 KIAA1570 Kinetochore-null protein 1 Protein CASC5 Protein D40/AF15q14 protein protein human Homo sapiens Human MDGVSSEANEENDNIERPVRRRHSSILKPPRSPLQDLRGGNERVQESNALRNKKNSRRVSFADTIKVFQTESHMKIVRKSEMEETETGENLLLIQNKKLEDNYCEITGMNTLLSAPIHTQMQQKEFSIIEHTRERKHANDQTVIFSDENQMDLTSSHTVMITKGLLDNPISEKSTKIDTTSFLANLKLHTEDSRMKKEVNFSVDQNTSSENKIDFNDFIKRLKTGKCSAFPDVPDKENFEIPIYSKEPNSASSTHQMHVSLKEDENNSNITRLFREKDDGMNFTQCHTANIQTLIPTSSETNSRESKGNDITIYGNDFMDLTFNHTLQILPATGNFSEIENQTQNAMDVTTGYGTKASGNKTVFKSKQNTAFQDLSINSADKIHITRSHIMGAETHIVSQTCNQDARILAMTPESIYSNPSIQGCKTVFYSSCNDAMEMTKCLSNMREEKNLLKHDSNYAKMYCNPDAMSSLTEKTIYSGEENMDITKSHTVAIDNQIFKQDQSNVQIAAAPTPEKEMMLQNLMTTSEDGKMNVNCNSVPHVSKERIQQSLSNPLSISLTDRKTELLSGENMDLTESHTSNLGSQVPLAAYNLAPESTSESHSQSKSSSDECEEITKSRNEPFQRSDIIAKNSLTDTWNKDKDWVLKILPYLDKDSPQSADCNQEIATSHNIVYCGGVLDKQITNRNTVSWEQSLFSTTKPLFSSGQFSMKNHDTAISSHTVKSVLGQNSKLAEPLRKSLSNPTPDYCHDKMIICSEEEQNMDLTKSHTVVIGFGPSELQELGKTNLEHTTGQLTTMNRQIAVKVEKCGKSPIEKSGVLKSNCIMDVLEDESVQKPKFPKEKQNVKIWGRKSVGGPKIDKTIVFSEDDKNDMDITKSYTIEINHRPLLEKRDCHLVPLAGTSETILYTCRQDDMEITRSHTTALECKTVSPDEITTRPMDKTVVFVDNHVELEMTESHTVFIDYQEKERTDRPNFELSQRKSLGTPTVICTPTEESVFFPGNGESDRLVANDSQLTPLEEWSNNRGPVEVADNMELSKSATCKNIKDVQSPGFLNEPLSSKSQRRKSLKLKNDKTIVFSENHKNDMDITQSCMVEIDNESALEDKEDFHLAGASKTILYSCGQDDMEITRSHTTALECKTLLPNEIAIRPMDKTVLFTDNYSDLEVTDSHTVFIDCQATEKILEENPKFGIGKGKNLGVSFPKDNSCVQEIAEKQALAVGNKIVLHTEQKQQLFAATNRTTNEIIKFHSAAMDEKVIGKVVDQACTLEKAQVESCQLNNRDRRNVDFTSSHATAVCGSSDNYSCLPNVISCTDNLEGSAMLLCDKDEEKANYCPVQNDLAYANDFASEYYLESEGQPLSAPCPLLEKEEVIQTSTKGQLDCVITLHKDQDLIKDPRNLLANQTLVYSQDLGEMTKLNSKRVSFKLPKDQMKVYVDDIYVIPQPHFSTDQPPLPKKGQSSINKEEVILSKAGNKSLNIIENSSAPICENKPKILNSEEWFAAACKKELKENIQTTNYNTALDFHSNSDVTKQVIQTHVNAGEAPDPVITSNVPCFHSIKPNLNNLNGKTGEFLAFQTVHLPPLPEQLLELGNKAHNDMHIVQATEIHNINIISSNAKDSRDEENKKSHNGAETTSLPPKTVFKDKVRRCSLGIFLPRLPNKRNCSVTGIDDLEQIPADTTDINHLETQPVSSKDSGIGSVAGKLNLSPSQYINEENLPVYPDEINSSDSINIETEEKALIETYQKEISPYENKMGKTCNSQKRTWVQEEEDIHKEKKIRKNEIKFSDTTQDREIFDHHTEEDIDKSANSVLIKNLSRTPSSCSSSLDSIKADGTSLDFSTYRSSQMESQFLRDTICEESLREKLQDGRITIREFFILLQVHILIQKPRQSNLPGNFTVNTPPTPEDLMLSQYVYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEELLDQLSLSEWDVVEWSDDQAVFTFVYDTIQLTITFEESVVGFPFLDKRYRKIVDVNFQSLLDEDQAPPSSLLVHKLIFQYVEEKESWKKTCTTQHQLPKMLEEFSLVVHHCRLLGEEIEYLKRWGPNYNLMNIDINNNELRLLFSSSAAFAKFEITLFLSAYYPSVPLPSTIQNHVGNTSQDDIATILSKVPLENNYLKNVVKQIYQDLFQDCHFYH DIP protein Q8NG31-2 original sequence version: 59 DIP protein Q8NG31-2 original sequence version: 72 DIP protein Q8NG31-2 original sequence version: 115 A04548DF87BCA275 cdc20_human Cell division cycle protein 20 homolog CDC20 p55CDC protein protein human Homo sapiens Human MAQFAFESDLHSLLQLDAPIPNAPPARWQRKAKEAAGPAPSPMRAANRSHSAGRTPGRTPGKSSSKVQTTPSKPGGDRYIPHRSAAQMEVASFLLSKENQPENSQTPTKKEHQKAWALNLNGFDVEEAKILRLSGKPQNAPEGYQNRLKVLYSQKATPGSSRKTCRYIPSLPDRILDAPEIRNDYYLNLVDWSSGNVLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWNSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLWRCFELDPARRREREKASAAKSSLIHQGIR DIP protein Q12834 original sequence version: 132 DIP protein Q12834 original sequence version: 74 DIP protein Q12834 original sequence version: 100 DIP protein Q12834 original sequence version: 118 DIP protein Q12834 original sequence version: 125 DIP protein Q12834 original sequence version: 114 DIP protein Q12834 original sequence version: 147 DIP protein Q12834 original sequence version: 162 FD5C967AF84089E8 bub3_human Mitotic checkpoint protein BUB3 BUB3 protein protein human Homo sapiens Human MTGSNEFKLNQPPEDGISSVKFSPNTSQFLLVSSWDTSVRLYDVPANSMRLKYQHTGAVLDCAFYDPTHAWSGGLDHQLKMHDLNTDQENLVGTHDAPIRCVEYCPEVNVMVTGSWDQTVKLWDPRTPCNAGTFSQPEKVYTLSVSGDRLIVGTAGRRVLVWDLRNMGYVQQRRESSLKYQTRCIRAFPNKQGYVLSSIEGRVAVEYLDPSPEVQKKKYAFKCHRLKENNIEQIYPVNAISFHNIHNTFATGGSDGFVNIWDPFNKKRLCQFHRYPTSIASLAFSNDGTTLAIASSYMYEMDDTEHPEDGIFIRQVTDAETKPKSPCT DIP protein O43684 original sequence version: 108 DIP protein O43684 original sequence version: 140 2915572A57368E5A knl1_human Kinetochore scaffold 1 KNL1 ALL1-fused gene from chromosome 15q14 protein Bub-linking kinetochore protein CASC5 Cancer susceptibility candidate gene 5 protein Cancer/testis antigen 29 KIAA1570 Kinetochore-null protein 1 Protein CASC5 Protein D40/AF15q14 protein protein human Homo sapiens Human MDGVSSEANEENDNIERPVRRRHSSILKPPRSPLQDLRGGNERVQESNALRNKKNSRRVSFADTIKVFQTESHMKIVRKSEMEGCSAMVPSQLQLLPPGFKRFSCLSLPETETGENLLLIQNKKLEDNYCEITGMNTLLSAPIHTQMQQKEFSIIEHTRERKHANDQTVIFSDENQMDLTSSHTVMITKGLLDNPISEKSTKIDTTSFLANLKLHTEDSRMKKEVNFSVDQNTSSENKIDFNDFIKRLKTGKCSAFPDVPDKENFEIPIYSKEPNSASSTHQMHVSLKEDENNSNITRLFREKDDGMNFTQCHTANIQTLIPTSSETNSRESKGNDITIYGNDFMDLTFNHTLQILPATGNFSEIENQTQNAMDVTTGYGTKASGNKTVFKSKQNTAFQDLSINSADKIHITRSHIMGAETHIVSQTCNQDARILAMTPESIYSNPSIQGCKTVFYSSCNDAMEMTKCLSNMREEKNLLKHDSNYAKMYCNPDAMSSLTEKTIYSGEENMDITKSHTVAIDNQIFKQDQSNVQIAAAPTPEKEMMLQNLMTTSEDGKMNVNCNSVPHVSKERIQQSLSNPLSISLTDRKTELLSGENMDLTESHTSNLGSQVPLAAYNLAPESTSESHSQSKSSSDECEEITKSRNEPFQRSDIIAKNSLTDTWNKDKDWVLKILPYLDKDSPQSADCNQEIATSHNIVYCGGVLDKQITNRNTVSWEQSLFSTTKPLFSSGQFSMKNHDTAISSHTVKSVLGQNSKLAEPLRKSLSNPTPDYCHDKMIICSEEEQNMDLTKSHTVVIGFGPSELQELGKTNLEHTTGQLTTMNRQIAVKVEKCGKSPIEKSGVLKSNCIMDVLEDESVQKPKFPKEKQNVKIWGRKSVGGPKIDKTIVFSEDDKNDMDITKSYTIEINHRPLLEKRDCHLVPLAGTSETILYTCRQDDMEITRSHTTALECKTVSPDEITTRPMDKTVVFVDNHVELEMTESHTVFIDYQEKERTDRPNFELSQRKSLGTPTVICTPTEESVFFPGNGESDRLVANDSQLTPLEEWSNNRGPVEVADNMELSKSATCKNIKDVQSPGFLNEPLSSKSQRRKSLKLKNDKTIVFSENHKNDMDITQSCMVEIDNESALEDKEDFHLAGASKTILYSCGQDDMEITRSHTTALECKTLLPNEIAIRPMDKTVLFTDNYSDLEVTDSHTVFIDCQATEKILEENPKFGIGKGKNLGVSFPKDNSCVQEIAEKQALAVGNKIVLHTEQKQQLFAATNRTTNEIIKFHSAAMDEKVIGKVVDQACTLEKAQVESCQLNNRDRRNVDFTSSHATAVCGSSDNYSCLPNVISCTDNLEGSAMLLCDKDEEKANYCPVQNDLAYANDFASEYYLESEGQPLSAPCPLLEKEEVIQTSTKGQLDCVITLHKDQDLIKDPRNLLANQTLVYSQDLGEMTKLNSKRVSFKLPKDQMKVYVDDIYVIPQPHFSTDQPPLPKKGQSSINKEEVILSKAGNKSLNIIENSSAPICENKPKILNSEEWFAAACKKELKENIQTTNYNTALDFHSNSDVTKQVIQTHVNAGEAPDPVITSNVPCFHSIKPNLNNLNGKTGEFLAFQTVHLPPLPEQLLELGNKAHNDMHIVQATEIHNINIISSNAKDSRDEENKKSHNGAETTSLPPKTVFKDKVRRCSLGIFLPRLPNKRNCSVTGIDDLEQIPADTTDINHLETQPVSSKDSGIGSVAGKLNLSPSQYINEENLPVYPDEINSSDSINIETEEKALIETYQKEISPYENKMGKTCNSQKRTWVQEEEDIHKEKKIRKNEIKFSDTTQDREIFDHHTEEDIDKSANSVLIKNLSRTPSSCSSSLDSIKADGTSLDFSTYRSSQMESQFLRDTICEESLREKLQDGRITIREFFILLQVHILIQKPRQSNLPGNFTVNTPPTPEDLMLSQYVYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEELLDQLSLSEWDVVEWSDDQAVFTFVYDTIQLTITFEESVVGFPFLDKRYRKIVDVNFQSLLDEDQAPPSSLLVHKLIFQYVEEKESWKKTCTTQHQLPKMLEEFSLVVHHCRLLGEEIEYLKRWGPNYNLMNIDINNNELRLLFSSSAAFAKFEITLFLSAYYPSVPLPSTIQNHVGNTSQDDIATILSKVPLENNYLKNVVKQIYQDLFQDCHFYH DIP protein Q8NG31 original sequence version: 72 DIP protein Q8NG31 original sequence version: 115 8E29150CA4F5B5C1 bub1b-bub3-2 12 19 unspecified role unspecified role prey prey human Homo sapiens Human 14 unspecified role unspecified role bait bait Venus-tag Venus-tag fluorescent prot tag fluorescent protein tag fluorescent prot tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human 18 unspecified role unspecified role prey prey human Homo sapiens Human 17 unspecified role unspecified role prey prey human Homo sapiens Human 15 unspecified role unspecified role prey prey human Homo sapiens Human association association knl1-bub1b-1 1 14 unspecified role unspecified role prey prey Region 57-220 Region 57-220 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 16 unspecified role unspecified role bait bait Region 227-250 Region 227-250 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association bub1b-knl1-1 5 14 unspecified role unspecified role unspecified role unspecified role Region 57-220 Region 57-220 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain O60566:p.[Tyr141Ala;Leu142Ala] Y141A/L142A mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain L A certain certain sequence position certain certain certain sequence position certain Y A This feature has been corrected as a result of our quality control procedures. The original label was 'Y141A/L142A'. Wed May 02 18:20:13 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'tyr141ala,leu142ala' Tue Jun 30 17:11:36 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Tyr141Ala;Leu142Ala]' O60566:p.[Leu128Ala;Leu131Ala] L128A/L131A mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain L A certain certain sequence position certain certain certain sequence position certain L A This feature has been corrected as a result of our quality control procedures. The original label was 'L128A/L131A'. Wed May 02 16:06:47 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu128ala,leu131ala' Tue Jun 30 17:42:26 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Leu128Ala;Leu131Ala]' ecolx Escherichia coli 16 unspecified role unspecified role unspecified role unspecified role Region 212-222 Region 212-222 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain in vitro In vitro direct interaction direct interaction bub1b-knl1-2 4 14 unspecified role unspecified role unspecified role unspecified role Region 57-220 Region 57-220 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 16 unspecified role unspecified role unspecified role unspecified role Region 212-222 Region 212-222 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain Q8NG31-2:p.[Ile213Ala;Phe215Ala;Phe218Ala] I213A/F215A/F218A mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain F A certain certain sequence position certain certain certain sequence position certain F A certain certain sequence position certain certain certain sequence position certain I A This feature has been corrected as a result of our quality control procedures. The original label was 'I213A/F215A/F218A'. Wed May 02 14:24:42 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ile213ala,phe215ala,phe218ala' Tue Jun 30 18:15:17 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Ile213Ala;Phe215Ala;Phe218Ala]' Q8NG31-2:p.[Phe215Ala;Phe218Ala] F215A/F218A mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain F A certain certain sequence position certain certain certain sequence position certain F A This feature has been corrected as a result of our quality control procedures. The original label was 'F215A/F218A'. Wed May 02 16:18:40 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe215ala,phe218ala' Tue Jun 30 17:30:15 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Phe215Ala;Phe218Ala]' Q8NG31-2:p.[Phe215Ala;Ile219Ala] F215A/I219A mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain I A certain certain sequence position certain certain certain sequence position certain F A This feature has been corrected as a result of our quality control procedures. The original label was 'F215A/I219A'. Wed May 02 17:54:40 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe215ala,ile219ala' Tue Jun 30 15:44:31 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Phe215Ala;Ile219Ala]' in vitro In vitro direct interaction direct interaction knl1-bub1b-2 3 14 unspecified role unspecified role prey prey Region 57-220 Region 57-220 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain O60566:p.[Leu128Ala;Leu131Ala] L128A/L131A mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain L A certain certain sequence position certain certain certain sequence position certain L A This feature has been corrected as a result of our quality control procedures. The original label was 'L128A/L131A'. Wed May 02 14:58:17 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu128ala,leu131ala' Tue Jun 30 16:52:00 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Leu128Ala;Leu131Ala]' O60566:p.[Tyr141Ala;Leu142Ala] Y141A/L142A mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain L A certain certain sequence position certain certain certain sequence position certain Y A This feature has been corrected as a result of our quality control procedures. The original label was 'Y141A/L142A'. Wed May 02 19:17:53 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'tyr141ala,leu142ala' Tue Jun 30 18:19:28 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Tyr141Ala;Leu142Ala]' yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 16 unspecified role unspecified role bait bait Region 225-250 Region 225-250 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association bub1b-knl1-3 2 14 unspecified role unspecified role unspecified role unspecified role Region 57-220 Region 57-220 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 16 unspecified role unspecified role unspecified role unspecified role Region 208-226 Region 208-226 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain in vitro In vitro direct interaction direct interaction bub3-bub1b-1 8 14 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 18 unspecified role unspecified role bait bait yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association bub1b-knl1-4 9 14 unspecified role unspecified role unspecified role unspecified role Region 57-220 Region 57-220 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 16 unspecified role unspecified role unspecified role unspecified role Region 208-226 Region 208-226 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain in vitro In vitro direct interaction direct interaction bub1b-knl1-5 10 14 unspecified role unspecified role unspecified role unspecified role Region 57-220 Region 57-220 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain O60566:p.[Tyr141Ala;Leu142Ala] Y141A/L142A mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain L A certain certain sequence position certain certain certain sequence position certain Y A This feature has been corrected as a result of our quality control procedures. The original label was 'Y141A/L142A'. Wed May 02 19:01:22 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'tyr141ala,leu142ala' Tue Jun 30 18:02:39 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Tyr141Ala;Leu142Ala]' O60566:p.[Leu128Ala;Leu131Ala] L128A/L131A mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain L A certain certain sequence position certain certain certain sequence position certain L A This feature has been corrected as a result of our quality control procedures. The original label was 'L128A/L131A'. Wed May 02 16:20:23 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu128ala,leu131ala' Tue Jun 30 18:46:11 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Leu128Ala;Leu131Ala]' ecolx Escherichia coli 16 unspecified role unspecified role unspecified role unspecified role Region 212-222 Region 212-222 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain in vitro In vitro direct interaction direct interaction bub1b-knl1-6 6 14 unspecified role unspecified role unspecified role unspecified role Region 57-220 Region 57-220 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 16 unspecified role unspecified role unspecified role unspecified role Region 208-226 Region 208-226 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain in vitro In vitro direct interaction direct interaction bub1b-knl1-7 7 14 unspecified role unspecified role unspecified role unspecified role Region 57-220 Region 57-220 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 16 unspecified role unspecified role unspecified role unspecified role Region 212-222 Region 212-222 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain Q8NG31-2:p.[Ile213Ala;Phe215Ala;Phe218Ala] I213A/F215A/F218A mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain F A certain certain sequence position certain certain certain sequence position certain F A certain certain sequence position certain certain certain sequence position certain I A This feature has been corrected as a result of our quality control procedures. The original label was 'I213A/F215A/F218A'. Wed May 02 15:27:13 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ile213ala,phe215ala,phe218ala' Tue Jun 30 17:12:30 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Ile213Ala;Phe215Ala;Phe218Ala]' Q8NG31-2:p.[Phe215Ala;Phe218Ala] F215A/F218A mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain F A certain certain sequence position certain certain certain sequence position certain F A This feature has been corrected as a result of our quality control procedures. The original label was 'F215A/F218A'. Wed May 02 19:41:59 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe215ala,phe218ala' Tue Jun 30 17:29:36 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Phe215Ala;Phe218Ala]' Q8NG31-2:p.[Phe215Ala;Ile219Ala] F215A/I219A mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain I A certain certain sequence position certain certain certain sequence position certain F A This feature has been corrected as a result of our quality control procedures. The original label was 'F215A/I219A'. Wed May 02 16:49:54 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe215ala,ile219ala' Tue Jun 30 18:42:21 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Phe215Ala;Ile219Ala]' in vitro In vitro direct interaction direct interaction bub1b-knl1-8 11 14 unspecified role unspecified role unspecified role unspecified role Region 57-220 Region 57-220 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 16 unspecified role unspecified role unspecified role unspecified role Region 208-226 Region 208-226 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain in vitro In vitro direct interaction direct interaction bub1b-cdc20-4 13 14 unspecified role unspecified role bait bait O60566:p.[Tyr141Ala;Leu142Ala] Y141A/L142A mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain L A certain certain sequence position certain certain certain sequence position certain Y A This feature has been corrected as a result of our quality control procedures. The original label was 'Y141A/L142A'. Wed May 02 18:50:15 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'tyr141ala,leu142ala' Tue Jun 30 16:50:01 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Tyr141Ala;Leu142Ala]' O60566:p.[Leu128Ala;Leu131Ala] L128A/L131A mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain L A certain certain sequence position certain certain certain sequence position certain L A This feature has been corrected as a result of our quality control procedures. The original label was 'L128A/L131A'. Wed May 02 17:48:59 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu128ala,leu131ala' Tue Jun 30 18:41:43 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Leu128Ala;Leu131Ala]' Venus-tag Venus-tag fluorescent prot tag fluorescent protein tag fluorescent prot tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human 17 unspecified role unspecified role prey prey human Homo sapiens Human 15 unspecified role unspecified role prey prey human Homo sapiens Human association association