DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Modular mechanism of Wnt signaling inhibition by Wnt inhibitory factor 1. Modular mechanism of Wnt signaling inhibition by Wnt inhibitory factor 1. Nature structural & molecular biology 2011 imex curation Malinauskas T., Aricescu AR., Lu W., Siebold C., Jones EY. Only protein-protein interactions in vitro In vitro spr surface plasmon resonance Optical biosensor BIAcore(r) BIAcore(r) Optical biosensor spr predetermined predetermined participant predetermined Malinauskas T., Aricescu AR., Lu W., Siebold C., Jones EY. DIP original experiment: DIP-218627X Nature structural & molecular biology 2011 IMEx Modular mechanism of Wnt signaling inhibition by Wnt inhibitory factor 1. wnt3a_mouse Protein Wnt-3a Wnt3a Wnt-3a protein protein mouse Mus musculus Mouse MAPLGYLLVLCSLKQALGSYPIWWSLAVGPQYSSLSTQPILCASIPGLVPKQLRFCRNYVEIMPSVAEGVKAGIQECQHQFRGRRWNCTTVSNSLAIFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGSAAICGCSSRLQGSPGEGWKWGGCSEDIEFGGMVSREFADARENRPDARSAMNRHNNEAGRQAIASHMHLKCKCHGLSGSCEVKTCWWSQPDFRTIGDFLKDKYDSASEMVVEKHRESRGWVETLRPRYTYFKVPTERDLVYYEASPNFCEPNPETGSFGTRDRTCNVSSHGIDGCDLLCCGRGHNARTERRREKCHCVFHWCCYVSCQECTRVYDVHTCK DIP protein P27467 original sequence version: 126 DIP protein P27467 original sequence version: 101 DIP protein P27467 original sequence version: 121 DIP protein P27467 original sequence version: 140 DIP protein P27467 original sequence version: 109 7ADFC5B38A8EFF63 wif1_human Wnt inhibitory factor 1 WIF1 UNQ191/PRO217 protein protein human Homo sapiens Human MARRSAFPAAALWLWSILLCLLALRAEAGPPQEESLYLWIDAHQARVLIGFEEDILIVSEGKMAPFTHDFRKAQQRMPAIPVNIHSMNFTWQAAGQAEYFYEFLSLRSLDKGIMADPTVNVPLLGTVPHKASVVQVGFPCLGKQDGVAAFEVDVIVMNSEGNTILQTPQNAIFFKTCQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGFYGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNKRYEASLIHALRPAGAQLRQHTPSLKKAEERRDPPESNYIW DIP protein Q9Y5W5 original sequence version: 99 32ADFA6644833E9D wnt3a-wif1-1 1 2 unspecified role unspecified role bait bait mouse Mus musculus Mouse 3 unspecified role unspecified role prey prey Region 35-346 Region 35-346 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain Q9Y5W5:p.Met77Trp M77W mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain M W This feature has been corrected as a result of our quality control procedures. The original label was 'M77W'. Wed May 02 17:56:24 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'met77trp' Tue Jun 30 17:56:49 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Met77Trp' human Homo sapiens Human direct interaction direct interaction