DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Nature structural & molecular biology 2011 imex curation Oberoi J., Fairall L., Watson PJ., Yang JC., Czimmerer Z., Kampmann T., Goult BT., Greenwood JA., Gooch JT., Kallenberger BC., Nagy L., Neuhaus D., Schwabe JW. Only protein-protein interactions in vitro In vitro fps fluorescence polarization spectroscopy Fluorescence anisotropy FPS FPS Fluorescence anisotropy fps predetermined predetermined participant predetermined Oberoi J., Fairall L., Watson PJ., Yang JC., Czimmerer Z., Kampmann T., Goult BT., Greenwood JA., Gooch JT., Kallenberger BC., Nagy L., Neuhaus D., Schwabe JW. DIP original experiment: DIP-255415X Nature structural & molecular biology 2011 IMEx Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Nature structural & molecular biology 2011 imex curation Oberoi J., Fairall L., Watson PJ., Yang JC., Czimmerer Z., Kampmann T., Goult BT., Greenwood JA., Gooch JT., Kallenberger BC., Nagy L., Neuhaus D., Schwabe JW. Only protein-protein interactions in vitro In vitro pull down pull down weight by comassie molecular weight estimation by coomasie staining weight by comassie Oberoi J., Fairall L., Watson PJ., Yang JC., Czimmerer Z., Kampmann T., Goult BT., Greenwood JA., Gooch JT., Kallenberger BC., Nagy L., Neuhaus D., Schwabe JW. DIP original experiment: DIP-255417X Nature structural & molecular biology 2011 IMEx Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Nature structural & molecular biology 2011 imex curation Oberoi J., Fairall L., Watson PJ., Yang JC., Czimmerer Z., Kampmann T., Goult BT., Greenwood JA., Gooch JT., Kallenberger BC., Nagy L., Neuhaus D., Schwabe JW. Only protein-protein interactions ecolx Escherichia coli molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Oberoi J., Fairall L., Watson PJ., Yang JC., Czimmerer Z., Kampmann T., Goult BT., Greenwood JA., Gooch JT., Kallenberger BC., Nagy L., Neuhaus D., Schwabe JW. DIP original experiment: DIP-255408X Nature structural & molecular biology 2011 IMEx Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Nature structural & molecular biology 2011 imex curation Oberoi J., Fairall L., Watson PJ., Yang JC., Czimmerer Z., Kampmann T., Goult BT., Greenwood JA., Gooch JT., Kallenberger BC., Nagy L., Neuhaus D., Schwabe JW. Only protein-protein interactions in vitro In vitro pull down pull down weight by comassie molecular weight estimation by coomasie staining weight by comassie Oberoi J., Fairall L., Watson PJ., Yang JC., Czimmerer Z., Kampmann T., Goult BT., Greenwood JA., Gooch JT., Kallenberger BC., Nagy L., Neuhaus D., Schwabe JW. DIP original experiment: DIP-255412X Nature structural & molecular biology 2011 IMEx Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Nature structural & molecular biology 2011 imex curation Oberoi J., Fairall L., Watson PJ., Yang JC., Czimmerer Z., Kampmann T., Goult BT., Greenwood JA., Gooch JT., Kallenberger BC., Nagy L., Neuhaus D., Schwabe JW. Only protein-protein interactions in vitro In vitro pull down pull down weight by comassie molecular weight estimation by coomasie staining weight by comassie Oberoi J., Fairall L., Watson PJ., Yang JC., Czimmerer Z., Kampmann T., Goult BT., Greenwood JA., Gooch JT., Kallenberger BC., Nagy L., Neuhaus D., Schwabe JW. DIP original experiment: DIP-255407X Nature structural & molecular biology 2011 IMEx Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Nature structural & molecular biology 2011 imex curation Oberoi J., Fairall L., Watson PJ., Yang JC., Czimmerer Z., Kampmann T., Goult BT., Greenwood JA., Gooch JT., Kallenberger BC., Nagy L., Neuhaus D., Schwabe JW. Only protein-protein interactions in vitro In vitro fps fluorescence polarization spectroscopy Fluorescence anisotropy FPS FPS Fluorescence anisotropy fps predetermined predetermined participant predetermined Oberoi J., Fairall L., Watson PJ., Yang JC., Czimmerer Z., Kampmann T., Goult BT., Greenwood JA., Gooch JT., Kallenberger BC., Nagy L., Neuhaus D., Schwabe JW. DIP original experiment: DIP-255414X Nature structural & molecular biology 2011 IMEx Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Nature structural & molecular biology 2011 imex curation Oberoi J., Fairall L., Watson PJ., Yang JC., Czimmerer Z., Kampmann T., Goult BT., Greenwood JA., Gooch JT., Kallenberger BC., Nagy L., Neuhaus D., Schwabe JW. Only protein-protein interactions ecolx Escherichia coli x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Oberoi J., Fairall L., Watson PJ., Yang JC., Czimmerer Z., Kampmann T., Goult BT., Greenwood JA., Gooch JT., Kallenberger BC., Nagy L., Neuhaus D., Schwabe JW. DIP original experiment: DIP-255409X Nature structural & molecular biology 2011 IMEx Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Nature structural & molecular biology 2011 imex curation Oberoi J., Fairall L., Watson PJ., Yang JC., Czimmerer Z., Kampmann T., Goult BT., Greenwood JA., Gooch JT., Kallenberger BC., Nagy L., Neuhaus D., Schwabe JW. Only protein-protein interactions in vitro In vitro molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Oberoi J., Fairall L., Watson PJ., Yang JC., Czimmerer Z., Kampmann T., Goult BT., Greenwood JA., Gooch JT., Kallenberger BC., Nagy L., Neuhaus D., Schwabe JW. DIP original experiment: DIP-255401X Nature structural & molecular biology 2011 IMEx Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Nature structural & molecular biology 2011 imex curation Oberoi J., Fairall L., Watson PJ., Yang JC., Czimmerer Z., Kampmann T., Goult BT., Greenwood JA., Gooch JT., Kallenberger BC., Nagy L., Neuhaus D., Schwabe JW. Only protein-protein interactions human Homo sapiens Human 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Oberoi J., Fairall L., Watson PJ., Yang JC., Czimmerer Z., Kampmann T., Goult BT., Greenwood JA., Gooch JT., Kallenberger BC., Nagy L., Neuhaus D., Schwabe JW. DIP original experiment: DIP-255410X Nature structural & molecular biology 2011 IMEx Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Nature structural & molecular biology 2011 imex curation Oberoi J., Fairall L., Watson PJ., Yang JC., Czimmerer Z., Kampmann T., Goult BT., Greenwood JA., Gooch JT., Kallenberger BC., Nagy L., Neuhaus D., Schwabe JW. Only protein-protein interactions in vitro In vitro pull down pull down weight by comassie molecular weight estimation by coomasie staining weight by comassie Oberoi J., Fairall L., Watson PJ., Yang JC., Czimmerer Z., Kampmann T., Goult BT., Greenwood JA., Gooch JT., Kallenberger BC., Nagy L., Neuhaus D., Schwabe JW. DIP original experiment: DIP-255403X Nature structural & molecular biology 2011 IMEx Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Nature structural & molecular biology 2011 imex curation Oberoi J., Fairall L., Watson PJ., Yang JC., Czimmerer Z., Kampmann T., Goult BT., Greenwood JA., Gooch JT., Kallenberger BC., Nagy L., Neuhaus D., Schwabe JW. Only protein-protein interactions in vitro In vitro pull down pull down weight by comassie molecular weight estimation by coomasie staining weight by comassie Oberoi J., Fairall L., Watson PJ., Yang JC., Czimmerer Z., Kampmann T., Goult BT., Greenwood JA., Gooch JT., Kallenberger BC., Nagy L., Neuhaus D., Schwabe JW. DIP original experiment: DIP-255404X Nature structural & molecular biology 2011 IMEx Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Nature structural & molecular biology 2011 imex curation Oberoi J., Fairall L., Watson PJ., Yang JC., Czimmerer Z., Kampmann T., Goult BT., Greenwood JA., Gooch JT., Kallenberger BC., Nagy L., Neuhaus D., Schwabe JW. Only protein-protein interactions in vitro In vitro pull down pull down weight by comassie molecular weight estimation by coomasie staining weight by comassie Oberoi J., Fairall L., Watson PJ., Yang JC., Czimmerer Z., Kampmann T., Goult BT., Greenwood JA., Gooch JT., Kallenberger BC., Nagy L., Neuhaus D., Schwabe JW. DIP original experiment: DIP-255405X Nature structural & molecular biology 2011 IMEx Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Nature structural & molecular biology 2011 imex curation Oberoi J., Fairall L., Watson PJ., Yang JC., Czimmerer Z., Kampmann T., Goult BT., Greenwood JA., Gooch JT., Kallenberger BC., Nagy L., Neuhaus D., Schwabe JW. Only protein-protein interactions in vitro In vitro pull down pull down weight by comassie molecular weight estimation by coomasie staining weight by comassie Oberoi J., Fairall L., Watson PJ., Yang JC., Czimmerer Z., Kampmann T., Goult BT., Greenwood JA., Gooch JT., Kallenberger BC., Nagy L., Neuhaus D., Schwabe JW. DIP original experiment: DIP-255406X Nature structural & molecular biology 2011 IMEx Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Nature structural & molecular biology 2011 imex curation Oberoi J., Fairall L., Watson PJ., Yang JC., Czimmerer Z., Kampmann T., Goult BT., Greenwood JA., Gooch JT., Kallenberger BC., Nagy L., Neuhaus D., Schwabe JW. Only protein-protein interactions human Homo sapiens Human 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Oberoi J., Fairall L., Watson PJ., Yang JC., Czimmerer Z., Kampmann T., Goult BT., Greenwood JA., Gooch JT., Kallenberger BC., Nagy L., Neuhaus D., Schwabe JW. DIP original experiment: DIP-255411X Nature structural & molecular biology 2011 IMEx Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Nature structural & molecular biology 2011 imex curation Oberoi J., Fairall L., Watson PJ., Yang JC., Czimmerer Z., Kampmann T., Goult BT., Greenwood JA., Gooch JT., Kallenberger BC., Nagy L., Neuhaus D., Schwabe JW. Only protein-protein interactions in vitro In vitro pull down pull down weight by comassie molecular weight estimation by coomasie staining weight by comassie Oberoi J., Fairall L., Watson PJ., Yang JC., Czimmerer Z., Kampmann T., Goult BT., Greenwood JA., Gooch JT., Kallenberger BC., Nagy L., Neuhaus D., Schwabe JW. DIP original experiment: DIP-255413X Nature structural & molecular biology 2011 IMEx Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Nature structural & molecular biology 2011 imex curation Oberoi J., Fairall L., Watson PJ., Yang JC., Czimmerer Z., Kampmann T., Goult BT., Greenwood JA., Gooch JT., Kallenberger BC., Nagy L., Neuhaus D., Schwabe JW. Only protein-protein interactions in vitro In vitro nmr nuclear magnetic resonance NMR NMR nmr predetermined predetermined participant predetermined Oberoi J., Fairall L., Watson PJ., Yang JC., Czimmerer Z., Kampmann T., Goult BT., Greenwood JA., Gooch JT., Kallenberger BC., Nagy L., Neuhaus D., Schwabe JW. DIP original experiment: DIP-255402X Nature structural & molecular biology 2011 IMEx Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Nature structural & molecular biology 2011 imex curation Oberoi J., Fairall L., Watson PJ., Yang JC., Czimmerer Z., Kampmann T., Goult BT., Greenwood JA., Gooch JT., Kallenberger BC., Nagy L., Neuhaus D., Schwabe JW. Only protein-protein interactions in vitro In vitro pull down pull down weight by comassie molecular weight estimation by coomasie staining weight by comassie Oberoi J., Fairall L., Watson PJ., Yang JC., Czimmerer Z., Kampmann T., Goult BT., Greenwood JA., Gooch JT., Kallenberger BC., Nagy L., Neuhaus D., Schwabe JW. DIP original experiment: DIP-255416X Nature structural & molecular biology 2011 IMEx Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. gps2_human G protein pathway suppressor 2 GPS2 protein protein human Homo sapiens Human MPALLERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQSDLTTLTSAAYQQSLTVHTGTHLLSMQGSPGGHNRPGTLMAADRAKQMFGPQVLTTRHYVGSAAAFAGTPEHGQFQGSPGGAYGTAQPPPHYGPTQPAYSPSQQLRAPSAFPAVQYLSQPQPQPYAVHGHFQPTQTGFLQPGGALSLQKQMEHANQQTGFSDSSSLRPMHPQALHPAPGLLASPQLPVQMQPAGKSGFAATSQPGPRLPFIQHSQNPRFYHK DIP protein Q13227 original sequence version: 63 DIP protein Q13227 original sequence version: 83 AE65DA578C978C9B a0a024rbs3_human hCG_25303 NCOR2 protein protein human Homo sapiens Human MSGSTQPVAQTWRATEPRYPPHSLSYPVQIARTHTDVGLLEYQHHSRDYASHLSPGSIIQPQRRRPSLLSEFQPGNERSQELHLRPESHSYLPELGKSEMEFIESKRPRLELLPDPLLRPSPLLATGQPAGSEDLTKDRSLTGKLEPVSPPSPPHTDPELELVPPRLSKEELIQNMDRVDREITMVEQQISKLKKKQQQLEEEAAKPPEPEKPVSPPPIESKHRSLVQIIYDENRKKAEAAHRILEGLGPQVELPLYNQPSDTRQYHENIKINQAMRKKLILYFKRRNHARKQWEQKFCQRYDQLMEAWEKKVERIENNPRRRAKESKVREYYEKQFPEIRKQRELQERMQSRVGQRGSGLSMSAARSEHEVSEIIDGLSEQENLEKQMRQLAVIPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEKPEVENDKEDLLKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITRSMANEANSEEAITPQQSAELASMELNESSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIQVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPTISNPPPLISSAKHPSVLERQIGAISQGMSVQLHVPYSEHAKAPVGPVTMGLPLPMDPKKLAPFSGVKQEQLSPRGQAGPPESLGVPTAQEASVLRGTALGSVPGGSITKGIPSTRVPSDSAITYRGSITHGTPADVLYKGTITRIIGEDSPSRLDRGREDSLPKGHVIYEGKKGHVLSYEGGMSVTQCSKEDGRSSSGPPHETAAPKRTYDMMEGRVGRAISSASIEGLMGRAIPPERHSPHHLKEQHHIRGSITQGIPRSYVEAQEDYLRREAKLLKREGTPPPPPPSRDLTEAYKTQALGPLKLKPAHEGLVATVKEAGRSIHEIPREELRHTPELPLAPRPLKEGSITQGTPLKYDTGASTTGSKKHDVRSLIGSPGRTFPPVHPLDVMADARALERACYEESLKSRPGTASSSGGSIARGAPVIVPELGKPRQSPLTYEDHGAPFAGHLPRGSPVTTREPTPRLQEGSLSSSKASQDRKLTSTPREIAKSPHSTVPEHHPHPISPYEHLLRGVSGVDLYRSHIPLAFDPTSIPRGIPLDAAAAYYLPRHLAPNPTYPHLYPPYLIRGYPDTAALENRQTIINDYITSQQMHHNAATAMAQRADMLRGLSPRESSLALNYAAGPRGIIDLSQVPHLPVLVPPTPGTPATAMDRLAYLPTAPQPFSSRHSSSPLSPGGPTHLTKPTTTSSSERERDRDRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGSSGSSGGGGGSSSRPASHSHAHQHSPISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSPVRPAATFPPATHCPLGGTLDGVYPTLMEPVLLPKEAPRVARPERPRADTGHAFLAKPPARSGLEPASSPSKGSEPRPLVPPVSGHATIARTPAKNLAPHHASPDPPAPPASASDPHREKTQSKPFSIQELELRSLGYHGSSYSPEGVEPVSPVSSPSLTHDKGLPKHLEELDKSHLEGELRPKQPGPVKLGGEAAHLPHLRPLPESQPSSSPLLQTAPGVKGHQRVVTLAQHISEVITQDYTRHHPQQLSAPLPAPLYSFPGASCPVLDLRRPPSDLYLPPPDHGAPARGSPHSEGGKRSPEPNKTSVLGGGEDGIEPVSPPEGMTEPGHSRSAVYPLLYRDGEQTEPSRMGSKSPGNTSQPPAFFSKLTESNSAMVKSKKQEINKKLNTHNRNEPEYNISQPGTEIFNMPAITGTGLMTYRSQAVQEHASTNMGLEAIIRKALMGKYDQWEESPPLSANAFNPLNASASLPAAMPITAADGRSDHTLTSPGGGGKAKVSGRPSSRKAKSPAPGLASGDRPPSVSSVHSEGDCNRRTPLTNRVWEDRPSSAGSTPFPYNPLIMRLQAGVMASPPPPGLPAGSGPLAGPHHAWDEEPKPLLCSQYETLSDSE DIP protein Q9Y618-3 original sequence version: 124 o60907-2 F-box-like/WD repeat-containing protein TBL1X TBL1X TBL1 SMAP55 Transducin beta-like protein 1X Transducin-beta-like protein 1, X-linked protein protein human Homo sapiens Human MSITSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGTLVPPAALISILQKGLQYVEAEISINEDGTVFDGRPIESLSLIDAVMPDVVQTRQQAFREKLAQQQASAAAAAAAATAAATAATTTSAGVSHQNPSKNREATVNGEENRAHSVNNHAKPMEIDGEVEIPSSKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNTNGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSYRGTGGIFEVCWNARGDKVGASASDGSVCVLDLRK DIP protein O60907-2 original sequence version: 102 gps2-tbl1x-1 15 20 unspecified role unspecified role prey prey Region 1-90 Region 1-90 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 18 unspecified role unspecified role bait bait Region 1-60 Region 1-60 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range Q13227:p.[His19Ala;Arg20Glu;Ile22Ala] H19A/R20E/I22A mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain I A certain certain sequence position certain certain certain sequence position certain R E certain certain sequence position certain certain certain sequence position certain H A This feature has been corrected as a result of our quality control procedures. The original label was 'H19A/R20E/I22A'. Wed May 02 20:16:33 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'his19ala,arg20glu,ile22ala' Tue Jun 30 19:47:15 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[His19Ala;Arg20Glu;Ile22Ala]' ecolx Escherichia coli physical association physical association ncor2-gps2-1 12 20 unspecified role unspecified role prey prey Region 1-90 Region 1-90 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 19 unspecified role unspecified role bait bait Region 167-297 Region 167-297 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined ecolx Escherichia coli 18 unspecified role unspecified role prey prey Region 1-90 Region 1-90 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli association association gps2-ncor2-1 8 19 unspecified role unspecified role unspecified role unspecified role Region 167-207 Region 167-207 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 18 unspecified role unspecified role unspecified role unspecified role Region 53-90 Region 53-90 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction tbl1x-1 7 20 unspecified role unspecified role unspecified role unspecified role Region 1-71 Region 1-71 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction tbl1x-2 3 20 unspecified role unspecified role unspecified role unspecified role Region 1-71 Region 1-71 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction gps2-ncor2-2 16 19 unspecified role unspecified role unspecified role unspecified role Region 167-207 Region 167-207 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 18 unspecified role unspecified role unspecified role unspecified role Region 53-90 Region 53-90 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction ncor2-tbl1x-1 17 20 unspecified role unspecified role prey prey Region 1-90 Region 1-90 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain O60907-2:p.Val60Asn V60N mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain V N This feature has been corrected as a result of our quality control procedures. The original label was 'V60N'. Wed May 02 17:13:30 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'val60asn' Tue Jun 30 17:22:19 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Val60Asn' O60907-2:p.Leu57Gln L57Q/A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain L Q Wed May 02 18:48:08 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu57gln' Tue Jun 30 17:59:39 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Leu57Gln' O60907-2:p.Pro45Gly P45G mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain P G This feature has been corrected as a result of our quality control procedures. The original label was 'P45G'. Wed May 02 16:08:33 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'pro45gly' Tue Jun 30 17:01:32 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Pro45Gly' O60907-2:p.Ile39Ala I39A mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain I A This feature has been corrected as a result of our quality control procedures. The original label was 'I39A'. Wed May 02 15:13:43 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ile39ala' Tue Jun 30 16:39:11 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ile39Ala' O60907-2:p.Leu57Ala mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength certain certain sequence position certain certain certain sequence position certain L A Wed May 02 17:37:53 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu57ala' Tue Jun 30 19:06:27 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Leu57Ala' ecolx Escherichia coli 19 unspecified role unspecified role bait bait GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Region 227-297 Region 227-297 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli physical association physical association tbl1x-gps2-1 13 20 unspecified role unspecified role bait bait Region 1-90 Region 1-90 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain His-tag His-tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecolx Escherichia coli 18 unspecified role unspecified role prey prey Region 1-90 Region 1-90 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli physical association physical association tbl1x-ncor2-1 9 19 unspecified role unspecified role prey prey Region 227-251 Region 227-251 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain A0A024RBS3:p.[His242Ala;Arg243Glu;Leu245Ala] H242A/R243E/L245A mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain L A certain certain sequence position certain certain certain sequence position certain R E certain certain sequence position certain certain certain sequence position certain H A This feature has been corrected as a result of our quality control procedures. The original label was 'H242A/R243E/L245A'. Wed May 02 16:07:05 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'his242ala,arg243glu,leu245ala' Tue Jun 30 18:34:22 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[His242Ala;Arg243Glu;Leu245Ala]' human Homo sapiens Human 20 unspecified role unspecified role bait bait Region 1-90 Region 1-90 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human physical association physical association ncor2-gps2-2 10 19 unspecified role unspecified role bait bait Region 167-207 Region 167-207 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined ecolx Escherichia coli 18 unspecified role unspecified role prey prey Region 53-90 Region 53-90 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli physical association physical association ncor2-tbl1x-2 14 19 unspecified role unspecified role bait bait Region 227-251 Region 227-251 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain A0A024RBS3:p.[His242Ala;Arg243Glu;Leu245Ala] H242A/R243E/L245A mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain L A certain certain sequence position certain certain certain sequence position certain R E certain certain sequence position certain certain certain sequence position certain H A This feature has been corrected as a result of our quality control procedures. The original label was 'H242A/R243E/L245A'. Wed May 02 16:44:42 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'his242ala,arg243glu,leu245ala' Tue Jun 30 16:20:26 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[His242Ala;Arg243Glu;Leu245Ala]' human Homo sapiens Human 20 unspecified role unspecified role prey prey Region 1-90 Region 1-90 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human physical association physical association ncor2-tbl1x-3 6 19 unspecified role unspecified role unspecified role unspecified role Region 227-260 Region 227-260 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain BODIPY-label BODIPY-label bodipy label bodipy label undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined ecolx Escherichia coli 20 unspecified role unspecified role unspecified role unspecified role Region 1-90 Region 1-90 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction ncor2-tbl1x-4 4 20 unspecified role unspecified role prey prey Region 1-90 Region 1-90 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 19 unspecified role unspecified role bait bait GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Region 227-297 Region 227-297 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain A0A024RBS3:p.[His242Ala;Arg243Glu;Leu245Ala] H242A/R243E/L245A mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain L A certain certain sequence position certain certain certain sequence position certain R E certain certain sequence position certain certain certain sequence position certain H A This feature has been corrected as a result of our quality control procedures. The original label was 'H242A/R243E/L245A'. Wed May 02 20:12:30 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'his242ala,arg243glu,leu245ala' Tue Jun 30 16:40:35 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[His242Ala;Arg243Glu;Leu245Ala]' ecolx Escherichia coli physical association physical association gps2-tbl1x-2 2 20 unspecified role unspecified role prey prey Region 1-90 Region 1-90 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain O60907-2:p.Val60Asn V60N mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain V N This feature has been corrected as a result of our quality control procedures. The original label was 'V60N'. Wed May 02 16:50:07 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'val60asn' Tue Jun 30 16:45:46 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Val60Asn' O60907-2:p.Leu57Gln L57Q/A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain L Q Wed May 02 19:17:10 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu57gln' Tue Jun 30 17:32:31 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Leu57Gln' O60907-2:p.Leu57Ala mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength certain certain sequence position certain certain certain sequence position certain L A Wed May 02 20:00:41 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu57ala' Tue Jun 30 18:03:26 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Leu57Ala' ecolx Escherichia coli 18 unspecified role unspecified role bait bait Region 1-60 Region 1-60 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecolx Escherichia coli physical association physical association ncor2-tbl1x-5 11 20 unspecified role unspecified role prey prey Region 1-71 Region 1-71 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 19 unspecified role unspecified role bait bait Region 227-297 Region 227-297 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined ecolx Escherichia coli physical association physical association tbl1x-gps2-2 5 20 unspecified role unspecified role bait bait Region 1-60 Region 1-60 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecolx Escherichia coli 18 unspecified role unspecified role prey prey Region 1-71 Region 1-71 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli physical association physical association gps2-tbl1x-3 1 18 unspecified role unspecified role unspecified role unspecified role Region 1-52 Region 1-52 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain BODIPY-label BODIPY-label bodipy label bodipy label n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecolx Escherichia coli 20 unspecified role unspecified role unspecified role unspecified role Region 1-90 Region 1-90 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction