DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Structure of the Drosophila apoptosome at 6.9 å resolution. Structure of the Drosophila apoptosome at 6.9 å resolution. Structure (London, England : 1993) 2011 imex curation Yuan S., Yu X., Topf M., Dorstyn L., Kumar S., Ludtke SJ., Akey CW. Only protein-protein interactions in vitro In vitro 3d-em 3D electron microscopy 3D-EM electron tomog predetermined predetermined participant predetermined Yuan S., Yu X., Topf M., Dorstyn L., Kumar S., Ludtke SJ., Akey CW. DIP original experiment: DIP-218741X Structure (London, England : 1993) 2011 IMEx Structure of the Drosophila apoptosome at 6.9 å resolution. Structure of the Drosophila apoptosome at 6.9 å resolution. Structure of the Drosophila apoptosome at 6.9 å resolution. Structure (London, England : 1993) 2011 imex curation Yuan S., Yu X., Topf M., Dorstyn L., Kumar S., Ludtke SJ., Akey CW. Only protein-protein interactions in vitro In vitro density sedimentation cosedimentation through density gradient density sedimentation predetermined predetermined participant predetermined Yuan S., Yu X., Topf M., Dorstyn L., Kumar S., Ludtke SJ., Akey CW. DIP original experiment: DIP-218740X Structure (London, England : 1993) 2011 IMEx Structure of the Drosophila apoptosome at 6.9 å resolution. Structure of the Drosophila apoptosome at 6.9 å resolution. Structure of the Drosophila apoptosome at 6.9 å resolution. Structure (London, England : 1993) 2011 imex curation Yuan S., Yu X., Topf M., Dorstyn L., Kumar S., Ludtke SJ., Akey CW. Only protein-protein interactions in vitro In vitro density sedimentation cosedimentation through density gradient density sedimentation predetermined predetermined participant predetermined Yuan S., Yu X., Topf M., Dorstyn L., Kumar S., Ludtke SJ., Akey CW. DIP original experiment: DIP-218742X Structure (London, England : 1993) 2011 IMEx Structure of the Drosophila apoptosome at 6.9 å resolution. Structure of the Drosophila apoptosome at 6.9 å resolution. Structure of the Drosophila apoptosome at 6.9 å resolution. Structure (London, England : 1993) 2011 imex curation Yuan S., Yu X., Topf M., Dorstyn L., Kumar S., Ludtke SJ., Akey CW. Only protein-protein interactions in vitro In vitro 3d-em 3D electron microscopy 3D-EM electron tomog predetermined predetermined participant predetermined Yuan S., Yu X., Topf M., Dorstyn L., Kumar S., Ludtke SJ., Akey CW. DIP original experiment: DIP-218743X Structure (London, England : 1993) 2011 IMEx Structure of the Drosophila apoptosome at 6.9 å resolution. dronc_drome Caspase Dronc Dronc NEDD2-like caspase Nc CG8091 protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MQPPELEIGMPKRHREHIRKNLNILVEWTNYERLAMECVQQGILTVQMLRNTQDLNGKPFNMDEKDVRVEQHRRLLLKITQRGPTAYNLLINALRNINCLDAAVLLESVDESDSRPPFISLNERRTSRKSADIVDTPSPEASEGPCVSKLRNEPLGALTPYVGVVDGPEVKKSKKIHGGDSAILGTYKMQSRFNRGVLLMVNIMDYPDQNRRRIGAEKDSKSLIHLFQELNFTIFPYGNVNQDQFFKLLTMVTSSSYVQNTECFVMVLMTHGNSVEGKEKVEFCDGSVVDMQKIKDHFQTAKCPYLVNKPKVLMFPFCRGDEYDLGHPKNQGNLMEPVYTAQEEKWPDTQTEGIPSPSTNVPSLADTLVCYANTPGYVTHRDLDTGSWYIQKFCQVMADHAHDTDLEDILKKTSEAVGNKRTKKGSMQTGAYDNLGFNKKLYFNPGFFNE DIP protein Q9XYF4 original sequence version: 92 640A9725202A7E65 q7kli1_drome Dark Ark Ark-RB Hac1 dapaf-1L APAF-1 APAF1 ARK Apaf-1 Apaf-I Apaf1 D-Apaf-1 DARK Dapaf-1 Dmel\CG6829 HAC-1 HAC1 Hac-1 T1 anon-53Fa apaf-1 apaf1 arc ark dAPAF-1 dApaf-1 dApaf1 dArk dapaf dapaf-1 dapaf-1S dark hac-1 hac1 l(2)SH0173 CG6829 Dmel_CG6829 Apaf protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MDFETGEHQYQYKDILSVFEDAFVDNFDCKDVQDMPKSILSKEEIDHIIMSKDAVSGTLRLFWTLLSKQEEMVQKFVEEVLRINYKFLMSPIKTEQRQPSMMTRMYIEQRDRLYNDNQVFAKYNVSRLQPYLKLRQALLELRPAKNVLIDGVLGSGKTWVALDVCLSYKVQCKMDFKIFWLNLKNCNSPETVLEMLQKLLYQIDPNWTSRSDHSSNIKLRIHSIQAELRRLLKSKPYENCLLVLLNVQNAKAWNAFNLSCKILLTTRFKQVTDFLSAATTTHISLDHHSMTLTPDEVKSLLLKYLDCRPQDLPREVLTTNPRRLSIIAESIRDGLATWDNWKHVNCDKLTTIIESSLNVLEPAEYRKMFDRLSVFPPSAHIPTILLSLIWFDVIKSDVMVVVNKLHKYSLVEKQPKESTISIPSIYLELKVKLENEYALHRSIVDHYNIPKTFDSDDLIPPYLDQYFYSHIGHHLKNIEHPERMTLFRMVFLDFRFLEQKIRHDSTAWNASGSILNTLQQLKFYKPYICDNDPKYERLVNAILDFLPKIEENLICSKYTDLLRIALMAEDEAIFEEAHKQVQRFDDRVWFTNHGRFHQHRQIINLGDNEGRHAVYLHNDFCLIALASGQILLTDVSLEGEDTYLLRDESDSSDILRMAVFNQQKHLITLHCNGSVKLWSLWPDCPGRRHSGGSKQQLVNSVVKRFIGSYANLKIVAFYLNEDAGLPEANIQLHVAFINGDVSILNWDEQDQEFKLSHVPVLKTMQSGIRCFVQVLKRYYVVCTSNCTLTVWDLTNGSSNTLELHVFNVENDTPLALDVFDERSKTATVLLIFKYSVWRLNFLPGLSVSLQSEAVQLPEGSFITCGKRSTDGRYLLLGTSEGLIVYDLKISDPVLRSNVSEHIECVDIYELFDPVYKYIVLCGAKGKQVVHVHTLRSVSGSNSHQNREIAWVHSADEISVMTKACLEPNVYLRSLMDMTRERTQLLAVDSKERIHLIKPAISRISEWSTITPTHAASNCKINAISAFNDEQIFVGYVDGVIIDVIHDTALPQQFIEEPIDYLKQVSPNILVASAHSAQKTVIFQLEKIDPLQPNDQWPLMMDVSTKYASLQEGQYIILFSDHGVCHLDIANPSAFVKPKDSEEYIVGFDLKNSLLFLAYENNIIDVFRLIFSCNQLRYEQICEEEIAQKAKISYLVATDDGTMLAMGFENGTLELFAVENRKVQLIYSIEEVHEHCIRQLLFSPCKLLLISCAEQLCFWNVTHMRNNQLEREQKRRRSRRHKQHSVTQEDAVDAAPIAADIDVDVTFVADEFHPVNRGTAELWRNKRGNAIRPELLACVKFVGNEARQFFTDAHFSHFYAIDDEGVYYHLQLLELSRLQPPPDPVTLDIANQYEDLKNLRILDSPLMQDSDSEGADVVGNLVLEKNGGVARATPILEEASS DIP protein Q7KLI1 original sequence version: 50 74EFEAD06E54FA74 dark-1 2 6 unspecified role unspecified role unspecified role unspecified role spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm direct interaction direct interaction dark-2 1 6 unspecified role unspecified role unspecified role unspecified role spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm direct interaction direct interaction dark-dronc-1 3 5 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli 6 unspecified role unspecified role unspecified role unspecified role spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm direct interaction direct interaction dark-dronc-2 4 5 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli 6 unspecified role unspecified role unspecified role unspecified role spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm direct interaction direct interaction