DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Alzheimer's disease peptide beta-amyloid interacts with fibrinogen and induces its oligomerization. Alzheimer's disease peptide beta-amyloid interacts with fibrinogen and induces its oligomerization. Proceedings of the National Academy of Sciences of the United States of America 2010 imex curation Ahn HJ., Zamolodchikov D., Cortes-Canteli M., Norris EH., Glickman JF., Strickland S., Ahn HJ., Zamolodchikov D., Cortes-Canteli M., Norris EH., Glickman JF., Strickland S. Alzheimers - Interactions investigated in the context of Alzheimers disease Only protein-protein interactions in vitro In vitro pull down pull down predetermined predetermined participant predetermined Ahn HJ., Zamolodchikov D., Cortes-Canteli M., Norris EH., Glickman JF., Strickland S. Alzheimers - Interactions investigated in the context of Alzheimers disease DIP original experiment: DIP-220646X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx Alzheimer's disease peptide beta-amyloid interacts with fibrinogen and induces its oligomerization. fibb_human Fibrinogen beta chain FGB protein protein human Homo sapiens Human MKRMVSWSFHKLKTMKHLLLLLLCVFLVKSQGVNDNEEGFFSARGHRPLDKKREEAPSLRPAPPPISGGGYRARPAKAAATQKKVERKAPDAGGCLHADPDLGVLCPTGCQLQEALLQQERPIRNSVDELNNNVEAVSQTSSSSFQYMYLLKDLWQKRQKQVKDNENVVNEYSSELEKHQLYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPFFPQQ DIP protein P02675 original sequence version: 111 DIP protein P02675 original sequence version: 153 DIP protein P02675 original sequence version: 149 DIP protein P02675 original sequence version: 147 B92FFB9976AB53C5 p05067-pro_0000000092 Amyloid-beta protein 42 Alzheimer disease amyloid protein Cerebral vascular amyloid peptide APP A4 AD1 ABPP PreA4 Protease nexin-II APPI Amyloid precursor protein Amyloid-beta A4 protein Alzheimer disease amyloid A4 protein homolog Amyloid-beta (A4) precursor protein protein protein human Homo sapiens Human DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA 672 713 3AC85563D7858C37 abeta(142)-fgb-1 1 3 unspecified role unspecified role bait bait Biotin-tag Biotin-tag biotin tag biotin tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined [EBI-15893522]N-terminal positions must always be 1. Actual positions : 0-0 [EBI-15893522]0-0 in vitro In vitro 2 unspecified role unspecified role prey prey Region 396-444 Region 396-444 sufficient to bind sufficient binding region sufficient to bind de novo protein sequence de novo protein sequencing by mass spectrometry de novo protein sequence MS/MS certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human direct interaction direct interaction