DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Structural basis of HIV-1 resistance to AZT by excision. Structural basis of HIV-1 resistance to AZT by excision. Nature structural & molecular biology 2010 imex curation Tu X., Das K., Han Q., Bauman JD., Clark AD., Hou X., Frenkel YV., Gaffney BL., Jones RA., Boyer PL., Hughes SH., Sarafianos SG., Arnold E. Only protein-protein interactions ecolx Escherichia coli x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Tu X., Das K., Han Q., Bauman JD., Clark AD., Hou X., Frenkel YV., Gaffney BL., Jones RA., Boyer PL., Hughes SH., Sarafianos SG., Arnold E. DIP original experiment: DIP-217652X Nature structural & molecular biology 2010 IMEx Structural basis of HIV-1 resistance to AZT by excision. Structural basis of HIV-1 resistance to AZT by excision. Structural basis of HIV-1 resistance to AZT by excision. Nature structural & molecular biology 2010 imex curation Tu X., Das K., Han Q., Bauman JD., Clark AD., Hou X., Frenkel YV., Gaffney BL., Jones RA., Boyer PL., Hughes SH., Sarafianos SG., Arnold E. Only protein-protein interactions ecolx Escherichia coli pull down pull down predetermined predetermined participant predetermined Tu X., Das K., Han Q., Bauman JD., Clark AD., Hou X., Frenkel YV., Gaffney BL., Jones RA., Boyer PL., Hughes SH., Sarafianos SG., Arnold E. DIP original experiment: DIP-217650X Nature structural & molecular biology 2010 IMEx Structural basis of HIV-1 resistance to AZT by excision. Structural basis of HIV-1 resistance to AZT by excision. Structural basis of HIV-1 resistance to AZT by excision. Nature structural & molecular biology 2010 imex curation Tu X., Das K., Han Q., Bauman JD., Clark AD., Hou X., Frenkel YV., Gaffney BL., Jones RA., Boyer PL., Hughes SH., Sarafianos SG., Arnold E. Only protein-protein interactions ecolx Escherichia coli ion exchange chrom ion exchange chromatography IEC IEC ion exchange chrom predetermined predetermined participant predetermined Tu X., Das K., Han Q., Bauman JD., Clark AD., Hou X., Frenkel YV., Gaffney BL., Jones RA., Boyer PL., Hughes SH., Sarafianos SG., Arnold E. DIP original experiment: DIP-217651X Nature structural & molecular biology 2010 IMEx Structural basis of HIV-1 resistance to AZT by excision. Structural basis of HIV-1 resistance to AZT by excision. Structural basis of HIV-1 resistance to AZT by excision. Nature structural & molecular biology 2010 imex curation Tu X., Das K., Han Q., Bauman JD., Clark AD., Hou X., Frenkel YV., Gaffney BL., Jones RA., Boyer PL., Hughes SH., Sarafianos SG., Arnold E. Only protein-protein interactions ecolx Escherichia coli pull down pull down predetermined predetermined participant predetermined Tu X., Das K., Han Q., Bauman JD., Clark AD., Hou X., Frenkel YV., Gaffney BL., Jones RA., Boyer PL., Hughes SH., Sarafianos SG., Arnold E. DIP original experiment: DIP-217649X Nature structural & molecular biology 2010 IMEx Structural basis of HIV-1 resistance to AZT by excision. p66 Reverse transcriptase protein protein 9hiv1 Human immunodeficiency virus 1 p51 Reverse transcriptase p51 subunit protein protein 9hiv1 Human immunodeficiency virus 1 p51-p66-1 3 6 unspecified role unspecified role unspecified role unspecified role Region 1-428 Region 1-428 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 5 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction p51-p66-2 4 6 unspecified role unspecified role bait bait His-tag His-tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal ecolx Escherichia coli 5 unspecified role unspecified role prey prey ecolx Escherichia coli physical association physical association p51-p66-3 1 6 unspecified role unspecified role unspecified role unspecified role Region 1-428 Region 1-428 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 5 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction p51-p66-4 2 6 unspecified role unspecified role bait bait His-tag His-tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag c-terminal c-terminal position c-term carboxy-terminus c-terminus c-term c-terminus carboxy-terminus c-terminal c-terminal c-terminal position c-term carboxy-terminus c-terminus c-term c-terminus carboxy-terminus c-terminal Region 1-428 Region 1-428 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 5 unspecified role unspecified role prey prey ecolx Escherichia coli physical association physical association