DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Structure and function of sphingosine-1-phosphate lyase, a key enzyme of sphingolipid metabolism. Structure and function of sphingosine-1-phosphate lyase, a key enzyme of sphingolipid metabolism. Structure (London, England : 1993) 2010 imex curation Bourquin F., Riezman H., Capitani G., Grütter MG. Only protein-protein interactions ecolx Escherichia coli solution sedimentati cosedimentation in solution solution sedimentati predetermined predetermined participant predetermined Bourquin F., Riezman H., Capitani G., Grütter MG. DIP original experiment: DIP-217137X Structure (London, England : 1993) 2010 IMEx Structure and function of sphingosine-1-phosphate lyase, a key enzyme of sphingolipid metabolism. Structure and function of sphingosine-1-phosphate lyase, a key enzyme of sphingolipid metabolism. Structure and function of sphingosine-1-phosphate lyase, a key enzyme of sphingolipid metabolism. Structure (London, England : 1993) 2010 imex curation Bourquin F., Riezman H., Capitani G., Grütter MG. Only protein-protein interactions ecolx Escherichia coli solution sedimentati cosedimentation in solution solution sedimentati predetermined predetermined participant predetermined Bourquin F., Riezman H., Capitani G., Grütter MG. DIP original experiment: DIP-217138X Structure (London, England : 1993) 2010 IMEx Structure and function of sphingosine-1-phosphate lyase, a key enzyme of sphingolipid metabolism. Structure and function of sphingosine-1-phosphate lyase, a key enzyme of sphingolipid metabolism. Structure and function of sphingosine-1-phosphate lyase, a key enzyme of sphingolipid metabolism. Structure (London, England : 1993) 2010 imex curation Bourquin F., Riezman H., Capitani G., Grütter MG. Only protein-protein interactions ecolx Escherichia coli molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Bourquin F., Riezman H., Capitani G., Grütter MG. DIP original experiment: DIP-217139X Structure (London, England : 1993) 2010 IMEx Structure and function of sphingosine-1-phosphate lyase, a key enzyme of sphingolipid metabolism. Structure and function of sphingosine-1-phosphate lyase, a key enzyme of sphingolipid metabolism. Structure and function of sphingosine-1-phosphate lyase, a key enzyme of sphingolipid metabolism. Structure (London, England : 1993) 2010 imex curation Bourquin F., Riezman H., Capitani G., Grütter MG. Only protein-protein interactions ecolx Escherichia coli molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Bourquin F., Riezman H., Capitani G., Grütter MG. DIP original experiment: DIP-217140X Structure (London, England : 1993) 2010 IMEx Structure and function of sphingosine-1-phosphate lyase, a key enzyme of sphingolipid metabolism. Structure and function of sphingosine-1-phosphate lyase, a key enzyme of sphingolipid metabolism. Structure and function of sphingosine-1-phosphate lyase, a key enzyme of sphingolipid metabolism. Structure (London, England : 1993) 2010 imex curation Bourquin F., Riezman H., Capitani G., Grütter MG. Only protein-protein interactions ecolx Escherichia coli x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Bourquin F., Riezman H., Capitani G., Grütter MG. DIP original experiment: DIP-217135X Structure (London, England : 1993) 2010 IMEx Structure and function of sphingosine-1-phosphate lyase, a key enzyme of sphingolipid metabolism. Structure and function of sphingosine-1-phosphate lyase, a key enzyme of sphingolipid metabolism. Structure and function of sphingosine-1-phosphate lyase, a key enzyme of sphingolipid metabolism. Structure (London, England : 1993) 2010 imex curation Bourquin F., Riezman H., Capitani G., Grütter MG. Only protein-protein interactions ecolx Escherichia coli x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Bourquin F., Riezman H., Capitani G., Grütter MG. DIP original experiment: DIP-217136X Structure (London, England : 1993) 2010 IMEx Structure and function of sphingosine-1-phosphate lyase, a key enzyme of sphingolipid metabolism. sgpl_yeast Sphingosine-1-phosphate lyase BST1 DPL1 YDR294C D9819.5 Sphingosine-1-phosphate aldolase Bestowed of sphingosine tolerance 1 protein protein yeast Saccharomyces cerevisiae Baker's yeast MSGVSNKTVSINGWYGMPIHLLREEGDFAQFMILTINELKIAIHGYLRNTPWYNMLKDYLFVIFCYKLISNFFYLLKVYGPVRLAVRTYEHSSRRLFRWLLDSPFLRGTVEKEVTKVKQSIEDELIRSDSQLMNFPQLPSNGIPQDDVIEELNKLNDLIPHTQWKEGKVSGAVYHGGDDLIHLQTIAYEKYCVANQLHPDVFPAVRKMESEVVSMVLRMFNAPSDTGCGTTTSGGTESLLLACLSAKMYALHHRGITEPEIIAPVTAHAGFDKAAYYFGMKLRHVELDPTTYQVDLGKVKKFINKNTILLVGSAPNFPHGIADDIEGLGKIAQKYKLPLHVDSCLGSFIVSFMEKAGYKNLPLLDFRVPGVTSISCDTHKYGFAPKGSSVIMYRNSDLRMHQYYVNPAWTGGLYGSPTLAGSRPGAIVVGCWATMVNMGENGYIESCQEIVGAAMKFKKYIQENIPDLNIMGNPRYSVISFSSKTLNIHELSDRLSKKGWHFNALQKPVALHMAFTRLSAHVVDEICDILRTTVQELKSESNSKPSPDGTSALYGVAGSVKTAGVADKLIVGFLDALYKLGPGEDTATK 75FAF8182AF72266 75FAF8182AF72266 q67py4_symth STH1274 protein protein symth symth MLSAFSPPLPCDPARSHPTPEFPSSLQDYCEIRGIQSQPPARRDPTMDWLASLRSQIKPYRDRFPSHARLPRAGLPRAEILAEIAAMGAAESPAWRDGYASGAVYHGDEHHIAFLNEVYALQSQSNPLHPDLWPSTAKFEAEVVAMTAHMLGGDAAGGTVCGTVTSGGTESLLLAMKTYRDWARATKGITAPEAVVPVSAHAAFDKAAQYFGIKLVRTPLDADYRADVAAMREAITPNTVVVAGSAPGYPHGVVDPIPEIAALAAEHGIGCHVDACLGGFILPWAERLGYPVPPFDFRLEGVTSVSADTHKYGYGAKGTSVILYRRPDLLHYQYFIAADWPGGLYFSPTFAGSRPGALSATAWAAMLSLGEEGYLDATRRILQAADRLKAGVRAIPSLKILGDPLWVIAVASDELNIYQVMEEMAGRGWRLNGLHRPPAFHVALTLRHTEPGVVDRFLADLQDAVAQVRAHPEKATGMAPVYGMAAAAPPELVRQVLTGFIDLLYEV AE4EF2F847858910 stspl-1 5 8 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction stspl-2 3 8 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction dpl1p-1 6 7 unspecified role unspecified role unspecified role unspecified role Region 103-589 Region 103-589 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction dpl1p-2 4 7 unspecified role unspecified role unspecified role unspecified role Region 103-589 Region 103-589 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction stspl-3 1 8 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction dpl1p-3 2 7 unspecified role unspecified role unspecified role unspecified role Region 103-589 Region 103-589 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction