DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu LRRC26 auxiliary protein allows BK channel activation at resting voltage without calcium. LRRC26 auxiliary protein allows BK channel activation at resting voltage without calcium. Nature 2010 imex curation Yan J., Aldrich RW. Only protein-protein interactions human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip predetermined predetermined participant predetermined Yan J., Aldrich RW. DIP original experiment: DIP-254341X Nature 2010 IMEx LRRC26 auxiliary protein allows BK channel activation at resting voltage without calcium. LRRC26 auxiliary protein allows BK channel activation at resting voltage without calcium. LRRC26 auxiliary protein allows BK channel activation at resting voltage without calcium. Nature 2010 imex curation Yan J., Aldrich RW. Only protein-protein interactions human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Yan J., Aldrich RW. DIP original experiment: DIP-254345X Nature 2010 IMEx LRRC26 auxiliary protein allows BK channel activation at resting voltage without calcium. LRRC26 auxiliary protein allows BK channel activation at resting voltage without calcium. LRRC26 auxiliary protein allows BK channel activation at resting voltage without calcium. Nature 2010 imex curation Yan J., Aldrich RW. Only protein-protein interactions human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Yan J., Aldrich RW. DIP original experiment: DIP-254343X Nature 2010 IMEx LRRC26 auxiliary protein allows BK channel activation at resting voltage without calcium. LRRC26 auxiliary protein allows BK channel activation at resting voltage without calcium. LRRC26 auxiliary protein allows BK channel activation at resting voltage without calcium. Nature 2010 imex curation Yan J., Aldrich RW. Only protein-protein interactions human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip predetermined predetermined participant predetermined Yan J., Aldrich RW. DIP original experiment: DIP-254344X Nature 2010 IMEx LRRC26 auxiliary protein allows BK channel activation at resting voltage without calcium. LRRC26 auxiliary protein allows BK channel activation at resting voltage without calcium. LRRC26 auxiliary protein allows BK channel activation at resting voltage without calcium. Nature 2010 imex curation Yan J., Aldrich RW. Only protein-protein interactions human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip predetermined predetermined participant predetermined Yan J., Aldrich RW. DIP original experiment: DIP-254342X Nature 2010 IMEx LRRC26 auxiliary protein allows BK channel activation at resting voltage without calcium. lrc26_human Leucine-rich repeat-containing protein 26 LRRC26 CAPC BK channel auxiliary gamma subunit LRRC26 Cytokeratin-associated protein in cancer protein protein human Homo sapiens Human MRGPSWSRPRPLLLLLLLLSPWPVWAQVSATASPSGSLGAPDCPEVCTCVPGGLASCSALSLPAVPPGLSLRLRALLLDHNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNPWGCGCALRPLCAWLRRHPLPASEAETVLCVWPGRLTLSPLTAFSDAAFSHCAQPLALRDLAVVYTLGPASFLVSLASCLALGSGLTACRARRRRLRTAALRPPRPPDPNPDPDPHGCASPADPGSPAAAAQA DIP protein Q2I0M4 original sequence version: 40 q12791-5 Calcium-activated potassium channel subunit alpha-1 KCNMA1 KCNMA SLO BK channel BKCA alpha Calcium-activated potassium channel, subfamily M subunit alpha-1 K(VCA)alpha KCa1.1 Maxi K channel Slo-alpha Slo1 Slowpoke homolog protein protein human Homo sapiens Human MANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIPVTMEVPCDSRGQRMWWAFLASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSVKDWAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKSSSVHSIPSTANRQNRPKSRESRDKQKYVQEERL DIP protein Q12791-5 original sequence version: 102 DIP protein Q12791-5 original sequence version: 115 kcma1_human Calcium-activated potassium channel subunit alpha-1 KCNMA1 KCNMA SLO Calcium-activated potassium channel, subfamily M subunit alpha-1 Maxi K channel BK channel K(VCA)alpha BKCA alpha KCa1.1 Slowpoke homolog Slo-alpha Slo1 protein protein human Homo sapiens Human MANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIPVTMEVPCDSRGQRMWWAFLASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSVKDWAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRPKMSIYKRMRRACCFDCGRSERDCSCMSGRVRGNVDTLERAFPLSSVSVNDCSTSFRAFEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKSSSVHSIPSTANRQNRPKSRESRDKQKYVQEERL DIP protein Q12791 original sequence version: 72 DIP protein Q12791 original sequence version: 102 DIP protein Q12791 original sequence version: 115 DF9BFEAF374BE553 kcnma1-lrrc26-1 1 8 unspecified role unspecified role bait bait human Homo sapiens Human 6 unspecified role unspecified role prey prey human Homo sapiens Human physical association physical association kcnma1-lrrc26-2 4 7 unspecified role unspecified role bait bait human Homo sapiens Human 6 unspecified role unspecified role prey prey Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range Transmembrane domain Region 262-282 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human physical association physical association kcnma1-lrrc26-3 5 8 unspecified role unspecified role bait bait human Homo sapiens Human 6 unspecified role unspecified role prey prey human Homo sapiens Human physical association physical association lrrc26-kcnma1-1 2 7 unspecified role unspecified role prey prey human Homo sapiens Human 6 unspecified role unspecified role bait bait human Homo sapiens Human physical association physical association lrrc26-kcnma1-2 3 8 unspecified role unspecified role prey prey human Homo sapiens Human 6 unspecified role unspecified role bait bait human Homo sapiens Human physical association physical association