DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Oxidation state of the XRCC1 N-terminal domain regulates DNA polymerase beta binding affinity. Oxidation state of the XRCC1 N-terminal domain regulates DNA polymerase beta binding affinity. Proceedings of the National Academy of Sciences of the United States of America 2010 imex curation Cuneo MJ., London RE. Only protein-protein interactions in vitro In vitro fluorescence spectr classical fluorescence spectroscopy fluorescence spectr predetermined predetermined participant predetermined Cuneo MJ., London RE. DIP original experiment: DIP-216400X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx Oxidation state of the XRCC1 N-terminal domain regulates DNA polymerase beta binding affinity. Oxidation state of the XRCC1 N-terminal domain regulates DNA polymerase beta binding affinity. Oxidation state of the XRCC1 N-terminal domain regulates DNA polymerase beta binding affinity. Proceedings of the National Academy of Sciences of the United States of America 2010 imex curation Cuneo MJ., London RE. Only protein-protein interactions in vitro In vitro saxs x ray scattering saxs predetermined predetermined participant predetermined Cuneo MJ., London RE. DIP original experiment: DIP-216399X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx Oxidation state of the XRCC1 N-terminal domain regulates DNA polymerase beta binding affinity. Oxidation state of the XRCC1 N-terminal domain regulates DNA polymerase beta binding affinity. Oxidation state of the XRCC1 N-terminal domain regulates DNA polymerase beta binding affinity. Proceedings of the National Academy of Sciences of the United States of America 2010 imex curation Cuneo MJ., London RE. Only protein-protein interactions in vitro In vitro x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Cuneo MJ., London RE. DIP original experiment: DIP-216401X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx Oxidation state of the XRCC1 N-terminal domain regulates DNA polymerase beta binding affinity. dpolb_rat DNA polymerase beta Polb protein protein rat Rattus norvegicus (Rat) Rat MSKRKAPQETLNGGITDMLVELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVTGIGPSAARKLVDEGIKTLEDLRKNEDKLNHHQRIGLKYFEDFEKRIPREEMLQMQDIVLNEVKKLDPEYIATVCGSFRRGAESSGDMDVLLTHPNFTSESSKQPKLLHRVVEQLQKVRFITDTLSKGETKFMGVCQLPSENDENEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEQDIFDYIQWRYREPKDRSE DIP protein P06766 original sequence version: 116 DIP protein P06766 original sequence version: 154 xrcc1_human DNA repair protein XRCC1 XRCC1 X-ray repair cross-complementing protein 1 protein protein human Homo sapiens Human MPEIRLRHVVSCSSQDSTHCAENLLKADTYRKWRAAKAGEKTISVVLQLEKEEQIHSVDIGNDGSAFVEVLVGSSAGGAGEQDYEVLLVTSSFMSPSESRSGSNPNRVRMFGPDKLVRAAAEKRWDRVKIVCSQPYSKDSPFGLSFVRFHSPPDKDEAEAPSQKVTVTKLGQFRVKEEDESANSLRPGALFFSRINKTSPVTASDPAGPSYAAATLQASSAASSASPVSRAIGSTSKPQESPKGKRKLDLNQEEKKTPSKPPAQLSPSVPKRPKLPAPTRTPATAPVPARAQGAVTGKPRGEGTEPRRPRAGPEELGKILQGVVVVLSGFQNPFRSELRDKALELGAKYRPDWTRDSTHLICAFANTPKYSQVLGLGGRIVRKEWVLDCHRMRRRLPSRRYLMAGPGSSSEEDEASHSGGSGDEAPKLPQKQPQTKTKPTQAAGPSSPQKPPTPEETKAASPVLQEDIDIEGVQSEGQDNGAEDSGDTEDELRRVAEQKEHRLPPGQEENGEDPYAGSTDENTDSEEHQEPPDLPVPELPDFFQGKHFFLYGEFPGDERRKLIRYVTAFNGELEDNMSDRVQFVITAQEWDPSFEEALMDNPSLAFVRPRWIYSCNEKQKLLPHQLYGVVPQA DIP protein P18887 original sequence version: 120 DIP protein P18887 original sequence version: 161 30DB3321234DBFC2 polb-xrcc1-1 2 4 unspecified role unspecified role unspecified role unspecified role Catalytic domain Region 91-335 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 5 unspecified role unspecified role unspecified role unspecified role N-terminal domain Region 1-151 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction polb-xrcc1-2 3 4 unspecified role unspecified role unspecified role unspecified role Catalytic domain Region 91-335 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 5 unspecified role unspecified role unspecified role unspecified role N-terminal domain Region 1-151 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction polb-xrcc1-3 1 4 unspecified role unspecified role unspecified role unspecified role Catalytic domain Region 91-335 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ABD-label ABD-label fluorescent dye fluorescent dye label fluorescent dye certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 5 unspecified role unspecified role unspecified role unspecified role N-terminal domain Region 1-181 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction