DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu T-cadherin structures reveal a novel adhesive binding mechanism. T-cadherin structures reveal a novel adhesive binding mechanism. Nature structural & molecular biology 2010 imex curation Ciatto C., Bahna F., Zampieri N., VanSteenhouse HC., Katsamba PS., Ahlsen G., Harrison OJ., Brasch J., Jin X., Posy S., Vendome J., Ranscht B., Jessell TM., Honig B., Shapiro L. Only protein-protein interactions ecolx Escherichia coli x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Ciatto C., Bahna F., Zampieri N., VanSteenhouse HC., Katsamba PS., Ahlsen G., Harrison OJ., Brasch J., Jin X., Posy S., Vendome J., Ranscht B., Jessell TM., Honig B., Shapiro L. DIP original experiment: DIP-217034X Nature structural & molecular biology 2010 IMEx T-cadherin structures reveal a novel adhesive binding mechanism. T-cadherin structures reveal a novel adhesive binding mechanism. T-cadherin structures reveal a novel adhesive binding mechanism. Nature structural & molecular biology 2010 imex curation Ciatto C., Bahna F., Zampieri N., VanSteenhouse HC., Katsamba PS., Ahlsen G., Harrison OJ., Brasch J., Jin X., Posy S., Vendome J., Ranscht B., Jessell TM., Honig B., Shapiro L. Only protein-protein interactions ecolx Escherichia coli solution sedimentati cosedimentation in solution solution sedimentati predetermined predetermined participant predetermined Ciatto C., Bahna F., Zampieri N., VanSteenhouse HC., Katsamba PS., Ahlsen G., Harrison OJ., Brasch J., Jin X., Posy S., Vendome J., Ranscht B., Jessell TM., Honig B., Shapiro L. DIP original experiment: DIP-217038X Nature structural & molecular biology 2010 IMEx T-cadherin structures reveal a novel adhesive binding mechanism. T-cadherin structures reveal a novel adhesive binding mechanism. T-cadherin structures reveal a novel adhesive binding mechanism. Nature structural & molecular biology 2010 imex curation Ciatto C., Bahna F., Zampieri N., VanSteenhouse HC., Katsamba PS., Ahlsen G., Harrison OJ., Brasch J., Jin X., Posy S., Vendome J., Ranscht B., Jessell TM., Honig B., Shapiro L. Only protein-protein interactions ecolx Escherichia coli x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Ciatto C., Bahna F., Zampieri N., VanSteenhouse HC., Katsamba PS., Ahlsen G., Harrison OJ., Brasch J., Jin X., Posy S., Vendome J., Ranscht B., Jessell TM., Honig B., Shapiro L. DIP original experiment: DIP-217036X Nature structural & molecular biology 2010 IMEx T-cadherin structures reveal a novel adhesive binding mechanism. T-cadherin structures reveal a novel adhesive binding mechanism. T-cadherin structures reveal a novel adhesive binding mechanism. Nature structural & molecular biology 2010 imex curation Ciatto C., Bahna F., Zampieri N., VanSteenhouse HC., Katsamba PS., Ahlsen G., Harrison OJ., Brasch J., Jin X., Posy S., Vendome J., Ranscht B., Jessell TM., Honig B., Shapiro L. Only protein-protein interactions in vitro In vitro spr surface plasmon resonance Optical biosensor BIAcore(r) BIAcore(r) Optical biosensor spr predetermined predetermined participant predetermined Ciatto C., Bahna F., Zampieri N., VanSteenhouse HC., Katsamba PS., Ahlsen G., Harrison OJ., Brasch J., Jin X., Posy S., Vendome J., Ranscht B., Jessell TM., Honig B., Shapiro L. DIP original experiment: DIP-217037X Nature structural & molecular biology 2010 IMEx T-cadherin structures reveal a novel adhesive binding mechanism. T-cadherin structures reveal a novel adhesive binding mechanism. T-cadherin structures reveal a novel adhesive binding mechanism. Nature structural & molecular biology 2010 imex curation Ciatto C., Bahna F., Zampieri N., VanSteenhouse HC., Katsamba PS., Ahlsen G., Harrison OJ., Brasch J., Jin X., Posy S., Vendome J., Ranscht B., Jessell TM., Honig B., Shapiro L. Only protein-protein interactions ecolx Escherichia coli solution sedimentati cosedimentation in solution solution sedimentati predetermined predetermined participant predetermined Ciatto C., Bahna F., Zampieri N., VanSteenhouse HC., Katsamba PS., Ahlsen G., Harrison OJ., Brasch J., Jin X., Posy S., Vendome J., Ranscht B., Jessell TM., Honig B., Shapiro L. DIP original experiment: DIP-217035X Nature structural & molecular biology 2010 IMEx T-cadherin structures reveal a novel adhesive binding mechanism. q8vdk4_mouse Cadherin-13 Cdh13 protein protein mouse Mus musculus Mouse MQPRTPLTLCVLLSQVLLVTSADDLECTPGFQQKVLHIHQPAEFIEDQPVLNLTFSDCKGNEKLHYEVSSPHFKVNSDGTLVALRNITAVGRTLFVHARTPHAEDMAELVIVGGKDIQGSLQDIFKFARTSPVPRQKRSIVVSPILIPENQRQPFPRDVGKVVDSDRPEGSKFRLTGKGVDQDPKGTFRINENTGSVSVTRTLDRETIATYQLYVETTDASGKTLEGPVPLEVIVIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFYIDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIVIDDKNDHSPKFTKKEFQATVEEGAVGVIVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGPSSTATVHITVLDVNEGPVFYPDPMMVTKQENISVGSVLLTVNATDPDSLQHQTIRYSVYKDPAGWLSINPINGTVDTTAVLDRESPFVHNSVYTALFLAIDSGNPPATGTGTLLITLEDINDNAPVIYPTVAEVCDDARNLSVVILGASDKDLHPNTDPFKFEIHKQTVPDKVWKISKINNTHALVSLLQNLNKANYNLPIMVTDSGKPPMTNITDLRVQVCSCKNSKVDCNGAGALHLSLSLLLLFSLLSLLSGL DIP protein Q8VDK4 original sequence version: 47 mint CA5CA791C46A2FFB cadh1_mouse Cadherin-1 Epithelial cadherin Uvomorulin ARC-1 Cdh1 protein protein mouse Mus musculus Mouse MGARCRSFSALLLLLQVSSWLCQELEPESCSPGFSSEVYTFPVPERHLERGHVLGRVRFEGCTGRPRTAFFSEDSRFKVATDGTITVKRHLKLHKLETSFLVRARDSSHRELSTKVTLKSMGHHHHRHHHRDPASESNPELLMFPSVYPGLRRQKRDWVIPPISCPENEKGEFPKNLVQIKSNRDKETKVFYSITGQGADKPPVGVFIIERETGWLKVTQPLDREAIAKYILYSHAVSSNGEAVEDPMEIVITVTDQNDNRPEFTQEVFEGSVAEGAVPGTSVMKVSATDADDDVNTYNAAIAYTIVSQDPELPHKNMFTVNRDTGVISVLTSGLDRESYPTYTLVVQAADLQGEGLSTTAKAVITVKDINDNAPVFNPSTYQGQVPENEVNARIATLKVTDDDAPNTPAWKAVYTVVNDPDQQFVVVTDPTTNDGILKTAKGLDFEAKQQYILHVRVENEEPFEGSLVPSTATVTVDVVDVNEAPIFMPAERRVEVPEDFGVGQEITSYTAREPDTFMDQKITYRIWRDTANWLEINPETGAIFTRAEMDREDAEHVKNSTYVALIIATDDGSPIATGTGTLLLVLLDVNDNAPIPEPRNMQFCQRNPQPHIITILDPDLPPNTSPFTAELTHGASVNWTIEYNDAAQESLILQPRKDLEIGEYKIHLKLADNQNKDQVTTLDVHVCDCEGTVNNCMKAGIVAAGLQVPAILGILGGILALLILILLLLLFLRRRTVVKEPLLPPDDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPQYRPRPANPDEIGNFIDENLKAADSDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDQDQDYDYLNEWGNRFKKLADMYGGGEDD DIP protein P09803 original sequence version: 92 DIP protein P09803 original sequence version: 116 DIP protein P09803 original sequence version: 124 DIP protein P09803 original sequence version: 128 DIP protein P09803 original sequence version: 141 DIP protein P09803 original sequence version: 174 7A6444148D3D5983 cad13_chick Cadherin-13 CDH13 Truncated cadherin protein protein chick Gallus gallus (Chicken) Chicken MQHKTQLTLSFLLSQVLLLACAEDLECTPGFQQKVFYIEQPFEFTEDQPILNLVFDDCKGNNKLNFEVSNPDFKVEHDGSLVALKNVSEAGRALFVHARSEHAEDMAEILIVGADEKHDALKEIFKIEGNLGIPRQKRAILATPILIPENQRPPFPRSVGKVIRSEGTEGAKFRLSGKGVDQDPKGIFRINEISGDVSVTRPLDREAIANYELEVEVTDLSGKIIDGPVRLDISVIDQNDNRPMFKEGPYVGHVMEGSPTGTTVMRMTAFDADDPSTDNALLRYNILKQTPTKPSPNMFYIDPEKGDIVTVVSPVLLDRETMETPKYELVIEAKDMGGHDVGLTGTATATILIDDKNDHPPEFTKKEFQATVKEGVTGVIVNLTVGDRDDPATGAWRAVYTIINGNPGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDPLIPDIAYGPSSTATVQITVEDVNEGPVFHPNPMTVTKQENIPIGSIVLTVNATDPDTLQHQTIRYSVYKDPASWLEINPTNGTVATTAVLDRESPHVQDNKYTALFLAIDSGNPPATGTGTLHITLEDVNDNVPSLYPTLAKVCDDAKDLRVVVLGASDKDLHPNTDPFKFELSKQSGPEKLWRINKLNNTHAQVVLLQNLKKANYNIPISVTDSGKPPLTNNTELKLQVCSCKKSRMDCSASDALHISMTLILLSLFSLFCL DIP protein P33150 original sequence version: 76 cdh13-cdh13-1 4 6 unspecified role unspecified role bait bait EC1-EC2 domain Region 140-355 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 6 unspecified role unspecified role prey prey EC1-EC2 domain Region 140-355 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain Q8VDK4:p.Arg152Glu R152E mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain R E This feature has been corrected as a result of our quality control procedures. The original label was 'R152E'. Wed May 02 16:45:03 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'arg152glu' Tue Jun 30 20:23:10 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Arg152Glu' Q8VDK4:p.[Arg152Glu;Asp278Ser] R152E/D278S mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain D S certain certain sequence position certain certain certain sequence position certain R E This feature has been corrected as a result of our quality control procedures. The original label was 'R152E/D278S'. Wed May 02 16:39:19 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'arg152glu,asp278ser' Tue Jun 30 20:25:46 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Arg152Glu;Asp278Ser]' Q8VDK4:p.Arg152Ser R152S mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain R S This feature has been corrected as a result of our quality control procedures. The original label was 'R152S'. Wed May 02 18:44:27 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'arg152ser' Tue Jun 30 19:15:06 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Arg152Ser' Q8VDK4:p.[Arg152Ser;Asp278Ser] R152S/D278S mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain D S certain certain sequence position certain certain certain sequence position certain R S This feature has been corrected as a result of our quality control procedures. The original label was 'R152S/D278S'. Wed May 02 19:47:50 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'arg152ser,asp278ser' Tue Jun 30 18:39:51 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Arg152Ser;Asp278Ser]' ecolx Escherichia coli direct interaction direct interaction cdh13-1 1 8 unspecified role unspecified role unspecified role unspecified role EC1-EC2 domain Region 140-355 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction cdh13-2 5 6 unspecified role unspecified role unspecified role unspecified role EC1-EC2 domain Region 140-355 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain Q8VDK4:p.Arg152Glu R152E mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain R E This feature has been corrected as a result of our quality control procedures. The original label was 'R152E'. Wed May 02 18:17:37 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'arg152glu' Tue Jun 30 18:12:00 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Arg152Glu' ecolx Escherichia coli direct interaction direct interaction cdh13-3 3 6 unspecified role unspecified role unspecified role unspecified role EC1-EC2 domain Region 140-355 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction cdh1-10 2 7 unspecified role unspecified role unspecified role unspecified role EC1-EC2 domain Region 157-369 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction