DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. Proceedings of the National Academy of Sciences of the United States of America 2010 imex curation Fu X., Yucer N., Liu S., Li M., Yi P., Mu JJ., Yang T., Chu J., Jung SY., O'Malley BW., Gu W., Qin J., Wang Y. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip predetermined predetermined participant predetermined Fu X., Yucer N., Liu S., Li M., Yi P., Mu JJ., Yang T., Chu J., Jung SY., O'Malley BW., Gu W., Qin J., Wang Y. DIP original experiment: DIP-254202X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. Proceedings of the National Academy of Sciences of the United States of America 2010 imex curation Fu X., Yucer N., Liu S., Li M., Yi P., Mu JJ., Yang T., Chu J., Jung SY., O'Malley BW., Gu W., Qin J., Wang Y. Only protein-protein interactions in vitro In vitro comigration in sds comigration in sds page comigration in sds predetermined predetermined participant predetermined Fu X., Yucer N., Liu S., Li M., Yi P., Mu JJ., Yang T., Chu J., Jung SY., O'Malley BW., Gu W., Qin J., Wang Y. DIP original experiment: DIP-254197X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. Proceedings of the National Academy of Sciences of the United States of America 2010 imex curation Fu X., Yucer N., Liu S., Li M., Yi P., Mu JJ., Yang T., Chu J., Jung SY., O'Malley BW., Gu W., Qin J., Wang Y. Only protein-protein interactions human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Fu X., Yucer N., Liu S., Li M., Yi P., Mu JJ., Yang T., Chu J., Jung SY., O'Malley BW., Gu W., Qin J., Wang Y. DIP original experiment: DIP-254190X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. Proceedings of the National Academy of Sciences of the United States of America 2010 imex curation Fu X., Yucer N., Liu S., Li M., Yi P., Mu JJ., Yang T., Chu J., Jung SY., O'Malley BW., Gu W., Qin J., Wang Y. Only protein-protein interactions human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip de novo protein sequence de novo protein sequencing by mass spectrometry de novo protein sequence Fu X., Yucer N., Liu S., Li M., Yi P., Mu JJ., Yang T., Chu J., Jung SY., O'Malley BW., Gu W., Qin J., Wang Y. DIP original experiment: DIP-254198X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. Proceedings of the National Academy of Sciences of the United States of America 2010 imex curation Fu X., Yucer N., Liu S., Li M., Yi P., Mu JJ., Yang T., Chu J., Jung SY., O'Malley BW., Gu W., Qin J., Wang Y. Only protein-protein interactions human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip predetermined predetermined participant predetermined Fu X., Yucer N., Liu S., Li M., Yi P., Mu JJ., Yang T., Chu J., Jung SY., O'Malley BW., Gu W., Qin J., Wang Y. DIP original experiment: DIP-254194X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. Proceedings of the National Academy of Sciences of the United States of America 2010 imex curation Fu X., Yucer N., Liu S., Li M., Yi P., Mu JJ., Yang T., Chu J., Jung SY., O'Malley BW., Gu W., Qin J., Wang Y. Only protein-protein interactions human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Fu X., Yucer N., Liu S., Li M., Yi P., Mu JJ., Yang T., Chu J., Jung SY., O'Malley BW., Gu W., Qin J., Wang Y. DIP original experiment: DIP-254192X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. Proceedings of the National Academy of Sciences of the United States of America 2010 imex curation Fu X., Yucer N., Liu S., Li M., Yi P., Mu JJ., Yang T., Chu J., Jung SY., O'Malley BW., Gu W., Qin J., Wang Y. Only protein-protein interactions in vitro In vitro comigration in sds comigration in sds page comigration in sds western blot western blot Immuno blot Immuno blot Fu X., Yucer N., Liu S., Li M., Yi P., Mu JJ., Yang T., Chu J., Jung SY., O'Malley BW., Gu W., Qin J., Wang Y. DIP original experiment: DIP-254203X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. Proceedings of the National Academy of Sciences of the United States of America 2010 imex curation Fu X., Yucer N., Liu S., Li M., Yi P., Mu JJ., Yang T., Chu J., Jung SY., O'Malley BW., Gu W., Qin J., Wang Y. Only protein-protein interactions in vitro In vitro pull down pull down predetermined predetermined participant predetermined Fu X., Yucer N., Liu S., Li M., Yi P., Mu JJ., Yang T., Chu J., Jung SY., O'Malley BW., Gu W., Qin J., Wang Y. DIP original experiment: DIP-254200X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. Proceedings of the National Academy of Sciences of the United States of America 2010 imex curation Fu X., Yucer N., Liu S., Li M., Yi P., Mu JJ., Yang T., Chu J., Jung SY., O'Malley BW., Gu W., Qin J., Wang Y. Only protein-protein interactions human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Fu X., Yucer N., Liu S., Li M., Yi P., Mu JJ., Yang T., Chu J., Jung SY., O'Malley BW., Gu W., Qin J., Wang Y. DIP original experiment: DIP-254191X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. Proceedings of the National Academy of Sciences of the United States of America 2010 imex curation Fu X., Yucer N., Liu S., Li M., Yi P., Mu JJ., Yang T., Chu J., Jung SY., O'Malley BW., Gu W., Qin J., Wang Y. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip predetermined predetermined participant predetermined Fu X., Yucer N., Liu S., Li M., Yi P., Mu JJ., Yang T., Chu J., Jung SY., O'Malley BW., Gu W., Qin J., Wang Y. DIP original experiment: DIP-254195X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. Proceedings of the National Academy of Sciences of the United States of America 2010 imex curation Fu X., Yucer N., Liu S., Li M., Yi P., Mu JJ., Yang T., Chu J., Jung SY., O'Malley BW., Gu W., Qin J., Wang Y. Only protein-protein interactions in vitro In vitro pull down pull down western blot western blot Immuno blot Immuno blot Fu X., Yucer N., Liu S., Li M., Yi P., Mu JJ., Yang T., Chu J., Jung SY., O'Malley BW., Gu W., Qin J., Wang Y. DIP original experiment: DIP-254201X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. Proceedings of the National Academy of Sciences of the United States of America 2010 imex curation Fu X., Yucer N., Liu S., Li M., Yi P., Mu JJ., Yang T., Chu J., Jung SY., O'Malley BW., Gu W., Qin J., Wang Y. Only protein-protein interactions in vitro In vitro pull down pull down predetermined predetermined participant predetermined Fu X., Yucer N., Liu S., Li M., Yi P., Mu JJ., Yang T., Chu J., Jung SY., O'Malley BW., Gu W., Qin J., Wang Y. DIP original experiment: DIP-254193X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. Proceedings of the National Academy of Sciences of the United States of America 2010 imex curation Fu X., Yucer N., Liu S., Li M., Yi P., Mu JJ., Yang T., Chu J., Jung SY., O'Malley BW., Gu W., Qin J., Wang Y. Only protein-protein interactions in vitro In vitro pull down pull down predetermined predetermined participant predetermined Fu X., Yucer N., Liu S., Li M., Yi P., Mu JJ., Yang T., Chu J., Jung SY., O'Malley BW., Gu W., Qin J., Wang Y. DIP original experiment: DIP-254199X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. Proceedings of the National Academy of Sciences of the United States of America 2010 imex curation Fu X., Yucer N., Liu S., Li M., Yi P., Mu JJ., Yang T., Chu J., Jung SY., O'Malley BW., Gu W., Qin J., Wang Y. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip predetermined predetermined participant predetermined Fu X., Yucer N., Liu S., Li M., Yi P., Mu JJ., Yang T., Chu J., Jung SY., O'Malley BW., Gu W., Qin J., Wang Y. DIP original experiment: DIP-254196X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. mdm2_human E3 ubiquitin-protein ligase Mdm2 MDM2 p53-binding protein Mdm2 Oncoprotein Mdm2 Double minute 2 protein RING-type E3 ubiquitin transferase Mdm2 protein protein human Homo sapiens Human MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP DIP protein Q00987 original sequence version: 93 DIP protein Q00987-1 original sequence version: 192 DIP protein Q00987 original sequence version: 88 DIP protein Q00987 original sequence version: 180 DIP protein Q00987 original sequence version: 188 DIP protein Q00987 original sequence version: 189 DIP protein Q00987 original sequence version: 115 DIP protein Q00987-1 original sequence version: null DIP protein Q00987 original sequence version: 149 DIP protein Q00987 original sequence version: 146 DIP protein Q00987 original sequence version: 140 DIP protein Q00987 original sequence version: 183 DIP protein Q00987 original sequence version: 145 DIP protein Q00987 original sequence version: 182 DIP protein Q00987 original sequence version: 151 DIP protein Q00987 original sequence version: 156 DIP protein Q00987-1 original sequence version: 160 DIP protein Q00987 original sequence version: 160 DIP protein Q00987 original sequence version: 168 DIP protein Q00987 original sequence version: 186 DIP protein Q00987 original sequence version: 206 F37CE163876BC983 rfwd3_human E3 ubiquitin-protein ligase RFWD3 RFWD3 RING finger and WD repeat domain-containing protein 3 RNF201 RING finger protein 201 protein protein human Homo sapiens Human MAHEAMEYDVQVQLNHAEQQPAPAGMASSQGGPALLQPVPADVVSSQGVPSILQPAPAEVISSQATPPLLQPAPQLSVDLTEVEVLGEDTVENINPRTSEQHRQGSDGNHTIPASSLHSMTNFISGLQRLHGMLEFLRPSSSNHSVGPMRTRRRVSASRRARAGGSQRTDSARLRAPLDAYFQVSRTQPDLPATTYDSETRNPVSEELQVSSSSDSDSDSSAEYGGVVDQAEESGAVILEEQLAGVSAEQEVTCIDGGKTLPKQPSPQKSEPLLPSASMDEEEGDTCTICLEQWTNAGDHRLSALRCGHLFGYRCISTWLKGQVRKCPQCNKKARHSDIVVLYARTLRALDTSEQERMKSSLLKEQMLRKQAELESAQCRLQLQVLTDKCTRLQRRVQDLQKLTSHQSQNLQQPRGSQAWVLSCSPSSQGQHKHKYHFQKTFTVSQAGNCRIMAYCDALSCLVISQPSPQASFLPGFGVKMLSTANMKSSQYIPMHGKQIRGLAFSSYLRGLLLSASLDNTIKLTSLETNTVVQTYNAGRPVWSCCWCLDEANYIYAGLANGSILVYDVRNTSSHVQELVAQKARCPLVSLSYMPRAASAAFPYGGVLAGTLEDASFWEQKMDFSHWPHVLPLEPGGCIDFQTENSSRHCLVTYRPDKNHTTIRSVLMEMSYRLDDTGNPICSCQPVHTFFGGPTCKLLTKNAIFQSPENDGNILVCTGDEAANSALLWDAASGSLLQDLQTDQPVLDICPFEVNRNSYLATLTEKMVHIYKWE DIP protein Q6PCD5 original sequence version: 68 EF6E0E186FD2E580 ubiq_human UBIQ_HUMAN protein protein human Homo sapiens Human MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG q00987-11 E3 ubiquitin-protein ligase Mdm2 MDM2 Double minute 2 protein Oncoprotein Mdm2 p53-binding protein Mdm2 RING-type E3 ubiquitin transferase Mdm2 protein protein human Homo sapiens Human MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP DIP protein Q00987-11 original sequence version: 149 DIP protein Q00987-11 original sequence version: 151 CFEC32F36132D8FA p53_human Cellular tumor antigen p53 TP53 P53 Tumor suppressor p53 Phosphoprotein p53 Antigen NY-CO-13 protein protein human Homo sapiens Human MEEPQSDPSVEPPLSQETFSDLWKLLPENNVLSPLPSQAMDDLMLSPDDIEQWFTEDPGPDEAPRMPEAAPPVAPAPAAPTPAAPAPAPSWPLSSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKMFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHERCSDSDGLAPPQHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRPILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLRKKGEPHHELPPGSTKRALPNNTSSSPQPKKKPLDGEYFTLQIRGRERFEMFRELNEALELKDAQAGKEPGGSRAHSSHLKSKKGQSTSRHKKLMFKTEGPDSD DIP protein P04637 original sequence version: 121 DIP protein P04637 original sequence version: 115 DIP protein P04637-1 original sequence version: 224 DIP protein P04637 original sequence version: 117 DIP protein P04637-1 original sequence version: 226 DIP protein P04637 original sequence version: 226 DIP protein P04637 original sequence version: 212 DIP protein P04637 original sequence version: 220 DIP protein P04637-1 original sequence version: 220 DIP protein P04637-1 original sequence version: 145 DIP protein P04637 original sequence version: 146 DIP protein P04637 original sequence version: 145 DIP protein P04637 original sequence version: 166 DIP protein P04637-1 original sequence version: 166 DIP protein P04637 original sequence version: 169 DIP protein P04637 original sequence version: 177 DIP protein P04637 original sequence version: 175 DIP protein P04637-1 original sequence version: 175 DIP protein P04637-1 original sequence version: 172 DIP protein P04637-1 original sequence version: 169 DIP protein P04637 original sequence version: 170 DIP protein P04637 original sequence version: 172 DIP protein P04637-1 original sequence version: 194 DIP protein P04637 original sequence version: 196 DIP protein P04637 original sequence version: 185 DIP protein P04637-1 original sequence version: 191 DIP protein P04637 original sequence version: 191 DIP protein P04637 original sequence version: 180 DIP protein P04637-1 original sequence version: 197 DIP protein P04637 original sequence version: 183 DIP protein P04637-1 original sequence version: 183 DIP protein P04637-1 original sequence version: 185 DIP protein P04637 original sequence version: 199 DIP protein P04637 original sequence version: 201 DIP protein P04637 original sequence version: 189 DIP protein P04637 original sequence version: 235 DIP protein P04637 original sequence version: 230 DIP protein P04637 original sequence version: 234 DIP protein P04637-1 original sequence version: 234 DIP protein P04637-1 original sequence version: 235 DIP protein P04637 original sequence version: 239 DIP protein P04637-1 original sequence version: 212 DIP protein P04637-1 original sequence version: 213 DIP protein P04637 original sequence version: 213 DIP protein P04637 original sequence version: 206 DIP protein P04637-1 original sequence version: 188 DIP protein P04637-1 original sequence version: 228 DIP protein P04637 original sequence version: 208 DIP protein P04637 original sequence version: 240 DIP protein P04637-1 original sequence version: 240 DIP protein P04637 original sequence version: 204 DIP protein P04637-1 original sequence version: 204 DIP protein P04637-1 original sequence version: 209 DIP protein P04637-1 original sequence version: 203 DIP protein P04637 original sequence version: 221 DIP protein P04637-1 original sequence version: 152 DIP protein P04637 original sequence version: 217 DIP protein P04637-1 original sequence version: 140 DIP protein P04637 original sequence version: 215 DIP protein P04637 original sequence version: 214 DIP protein P04637-1 original sequence version: 182 DIP protein P04637 original sequence version: 182 DIP protein P04637 original sequence version: 188 DIP protein P04637 original sequence version: 192 DIP protein P04637-1 original sequence version: 192 DIP protein P04637 original sequence version: 218 DIP protein P04637-1 original sequence version: 218 AD5C149FD8106131 tp53-ub-11 5 19 unspecified role unspecified role bait bait human Homo sapiens Human 17 unspecified role unspecified role prey prey HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal human Homo sapiens Human physical association physical association rfwd3-mdm2-1 3 19 unspecified role unspecified role prey prey human Homo sapiens Human 15 unspecified role unspecified role prey prey human Homo sapiens Human 16 unspecified role unspecified role bait bait human Homo sapiens Human association association rfwd3-tp53-1 13 19 unspecified role unspecified role prey prey Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecolx Escherichia coli 16 unspecified role unspecified role bait bait GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecolx Escherichia coli direct interaction direct interaction rfwd3-mdm2-2 4 15 unspecified role unspecified role prey prey human Homo sapiens Human 16 unspecified role unspecified role bait bait human Homo sapiens Human physical association physical association rfwd3-mdm2-3 1 18 unspecified role unspecified role prey prey Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human Homo sapiens Human 16 unspecified role unspecified role bait bait V5-tag V5-tag v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human physical association physical association tp53-rfwd3-1 9 19 unspecified role unspecified role bait bait human Homo sapiens Human 16 unspecified role unspecified role prey prey human Homo sapiens Human physical association physical association rfwd3-mdm2-4 8 18 unspecified role unspecified role prey prey His-tag His-tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined ecolx Escherichia coli 16 unspecified role unspecified role bait bait GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecolx Escherichia coli direct interaction direct interaction tp53-ub-12 10 19 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human 17 unspecified role unspecified role prey prey HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal human Homo sapiens Human physical association physical association tp53-ub-13 7 19 unspecified role unspecified role unspecified role unspecified role Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecolx Escherichia coli 17 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction tp53-mdm2-32 6 16 unspecified role unspecified role prey prey human Homo sapiens Human 15 unspecified role unspecified role prey prey human Homo sapiens Human 19 unspecified role unspecified role bait bait human Homo sapiens Human association association mdm2-rfwd3-1 14 18 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human Homo sapiens Human 16 unspecified role unspecified role prey prey V5-tag V5-tag v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human physical association physical association rfwd3-mdm2-5 11 18 unspecified role unspecified role prey prey His-tag His-tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Region 126-497 Region 126-497 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain Region 1-439 Region 1-439 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain region Δ185-285 required to bind necessary binding region required to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain This feature has been corrected as a result of our quality control procedures. The original label was 'Δ185-285'. ecolx Escherichia coli 16 unspecified role unspecified role bait bait GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecolx Escherichia coli direct interaction direct interaction rfwd3-mdm2-6 12 19 unspecified role unspecified role prey prey Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecolx Escherichia coli 18 unspecified role unspecified role prey prey His-tag His-tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined ecolx Escherichia coli 16 unspecified role unspecified role bait bait GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecolx Escherichia coli association association rfwd3-ub-1 2 17 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli 16 unspecified role unspecified role unspecified role unspecified role GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecolx Escherichia coli direct interaction direct interaction