DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Phosphorylation of aquaporin-2 regulates its endocytosis and protein-protein interactions. Phosphorylation of aquaporin-2 regulates its endocytosis and protein-protein interactions. Proceedings of the National Academy of Sciences of the United States of America 2010 imex curation Moeller HB., Praetorius J., Rützler MR., Fenton RA. Only protein-protein interactions canlf Canis familiaris (dog) Canis lupus familiaris Dog Canis familiaris anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Moeller HB., Praetorius J., Rützler MR., Fenton RA. DIP original experiment: DIP-215861X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx Phosphorylation of aquaporin-2 regulates its endocytosis and protein-protein interactions. Phosphorylation of aquaporin-2 regulates its endocytosis and protein-protein interactions. Phosphorylation of aquaporin-2 regulates its endocytosis and protein-protein interactions. Proceedings of the National Academy of Sciences of the United States of America 2010 imex curation Moeller HB., Praetorius J., Rützler MR., Fenton RA. Only protein-protein interactions canlf Canis familiaris (dog) Canis lupus familiaris Dog Canis familiaris anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Moeller HB., Praetorius J., Rützler MR., Fenton RA. DIP original experiment: DIP-215862X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx Phosphorylation of aquaporin-2 regulates its endocytosis and protein-protein interactions. hsp71_canlf Heat shock 70 kDa protein 1 HSPA1 Hsp70 protein protein canlf Canis familiaris (dog) Canis lupus familiaris Dog Canis familiaris MAKSAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVVNDGDKPKVQVSYKGETKAFYPEEISSMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRDRVSAKNALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELEQVCNPIITGLYQGAGGPGAGGFGAQAPKGGSGSGPTIEEVD DIP protein Q7YQC6 original sequence version: 57 mint In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage D1D80C3689346C88 anxa2_canlf Annexin A2 ANX2 ANXA2 Annexin-2 protein protein canlf Canis familiaris (dog) Canis lupus familiaris Dog Canis familiaris MSTVHEILCKLSLEGDHSTPPSAYGSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNEQRQDIAFAYQRRTKKELASALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARDLYDAGVKRKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKGDYQKALLYLCGGDD DIP protein Q6TEQ7 original sequence version: 50 Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity mint 91BE3A08FF76260E aqp2_mouse Aquaporin-2 Aqp2 ADH water channel Aquaporin-CD Collecting duct water channel protein WCH-CD Water channel protein for renal collecting duct cph protein protein mouse Mus musculus Mouse MWELRSIAFSRAVLAEFLATLLFVFFGLGSALQWASSPPSVLQIAVAFGLGIGTLVQALGHVSGAHINPAVTVACLVGCHVSFLRAAFYVAAQLLGAVAGAAILHEITPVEIRGDLAVNALHNNATAGQAVTVELFLTMQLVLCIFASTDERRSDNLGSPALSIGFSVTLGHLLGIYFTGCSMNPARSLAPAVVTGKFDDHWVFWIGPLVGAVIGSLLYNYLLFPSTKSLQERLAVLKGLEPDTDWEEREVRRRQSVELHSPQSLPRGSKA DIP protein P56402 original sequence version: 86 aqp2-anxa2-1 1 4 unspecified role unspecified role prey prey canlf Canis familiaris (dog) Canis lupus familiaris Dog Canis familiaris 5 unspecified role unspecified role bait bait P56402:p.Ser256Ala S256A mutation increasing mutation increasing interaction mutation increasing mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain S A This feature has been corrected as a result of our quality control procedures. The original label was 'S256A'. Wed May 02 16:55:22 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ser256ala' Tue Jun 30 19:32:41 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ser256Ala' canlf Canis familiaris (dog) Canis lupus familiaris Dog Canis familiaris physical association physical association aqp2-hspa1-1 2 3 unspecified role unspecified role prey prey canlf Canis familiaris (dog) Canis lupus familiaris Dog Canis familiaris 5 unspecified role unspecified role bait bait P56402:p.Ser269Asp S269D mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain S D This feature has been corrected as a result of our quality control procedures. The original label was 'S269D'. Wed May 02 15:25:16 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ser269asp' Tue Jun 30 19:26:52 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ser269Asp' canlf Canis familiaris (dog) Canis lupus familiaris Dog Canis familiaris physical association physical association