DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Proceedings of the National Academy of Sciences of the United States of America 2009 imex curation Kline CF., Kurata HT., Hund TJ., Cunha SR., Koval OM., Wright PJ., Christensen M., Anderson ME., Nichols CG., Mohler PJ. Only protein-protein interactions mouse Mus musculus Mouse anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Kline CF., Kurata HT., Hund TJ., Cunha SR., Koval OM., Wright PJ., Christensen M., Anderson ME., Nichols CG., Mohler PJ. DIP original experiment: DIP-216472X Proceedings of the National Academy of Sciences of the United States of America 2009 IMEx Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Proceedings of the National Academy of Sciences of the United States of America 2009 imex curation Kline CF., Kurata HT., Hund TJ., Cunha SR., Koval OM., Wright PJ., Christensen M., Anderson ME., Nichols CG., Mohler PJ. Only protein-protein interactions human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip predetermined predetermined participant predetermined Kline CF., Kurata HT., Hund TJ., Cunha SR., Koval OM., Wright PJ., Christensen M., Anderson ME., Nichols CG., Mohler PJ. DIP original experiment: DIP-216468X Proceedings of the National Academy of Sciences of the United States of America 2009 IMEx Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Proceedings of the National Academy of Sciences of the United States of America 2009 imex curation Kline CF., Kurata HT., Hund TJ., Cunha SR., Koval OM., Wright PJ., Christensen M., Anderson ME., Nichols CG., Mohler PJ. Only protein-protein interactions in vitro In vitro pull down pull down predetermined predetermined participant predetermined Kline CF., Kurata HT., Hund TJ., Cunha SR., Koval OM., Wright PJ., Christensen M., Anderson ME., Nichols CG., Mohler PJ. DIP original experiment: DIP-216463X Proceedings of the National Academy of Sciences of the United States of America 2009 IMEx Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Proceedings of the National Academy of Sciences of the United States of America 2009 imex curation Kline CF., Kurata HT., Hund TJ., Cunha SR., Koval OM., Wright PJ., Christensen M., Anderson ME., Nichols CG., Mohler PJ. Only protein-protein interactions human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Kline CF., Kurata HT., Hund TJ., Cunha SR., Koval OM., Wright PJ., Christensen M., Anderson ME., Nichols CG., Mohler PJ. DIP original experiment: DIP-216467X Proceedings of the National Academy of Sciences of the United States of America 2009 IMEx Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Proceedings of the National Academy of Sciences of the United States of America 2009 imex curation Kline CF., Kurata HT., Hund TJ., Cunha SR., Koval OM., Wright PJ., Christensen M., Anderson ME., Nichols CG., Mohler PJ. Only protein-protein interactions rat Rattus norvegicus (Rat) Rat anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Kline CF., Kurata HT., Hund TJ., Cunha SR., Koval OM., Wright PJ., Christensen M., Anderson ME., Nichols CG., Mohler PJ. DIP original experiment: DIP-216462X Proceedings of the National Academy of Sciences of the United States of America 2009 IMEx Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Proceedings of the National Academy of Sciences of the United States of America 2009 imex curation Kline CF., Kurata HT., Hund TJ., Cunha SR., Koval OM., Wright PJ., Christensen M., Anderson ME., Nichols CG., Mohler PJ. Only protein-protein interactions mouse Mus musculus Mouse anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Kline CF., Kurata HT., Hund TJ., Cunha SR., Koval OM., Wright PJ., Christensen M., Anderson ME., Nichols CG., Mohler PJ. DIP original experiment: DIP-216471X Proceedings of the National Academy of Sciences of the United States of America 2009 IMEx Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Proceedings of the National Academy of Sciences of the United States of America 2009 imex curation Kline CF., Kurata HT., Hund TJ., Cunha SR., Koval OM., Wright PJ., Christensen M., Anderson ME., Nichols CG., Mohler PJ. Only protein-protein interactions human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip predetermined predetermined participant predetermined Kline CF., Kurata HT., Hund TJ., Cunha SR., Koval OM., Wright PJ., Christensen M., Anderson ME., Nichols CG., Mohler PJ. DIP original experiment: DIP-216470X Proceedings of the National Academy of Sciences of the United States of America 2009 IMEx Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Proceedings of the National Academy of Sciences of the United States of America 2009 imex curation Kline CF., Kurata HT., Hund TJ., Cunha SR., Koval OM., Wright PJ., Christensen M., Anderson ME., Nichols CG., Mohler PJ. Only protein-protein interactions human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip predetermined predetermined participant predetermined Kline CF., Kurata HT., Hund TJ., Cunha SR., Koval OM., Wright PJ., Christensen M., Anderson ME., Nichols CG., Mohler PJ. DIP original experiment: DIP-216469X Proceedings of the National Academy of Sciences of the United States of America 2009 IMEx Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Proceedings of the National Academy of Sciences of the United States of America 2009 imex curation Kline CF., Kurata HT., Hund TJ., Cunha SR., Koval OM., Wright PJ., Christensen M., Anderson ME., Nichols CG., Mohler PJ. Only protein-protein interactions in vitro In vitro pull down pull down predetermined predetermined participant predetermined Kline CF., Kurata HT., Hund TJ., Cunha SR., Koval OM., Wright PJ., Christensen M., Anderson ME., Nichols CG., Mohler PJ. DIP original experiment: DIP-216464X Proceedings of the National Academy of Sciences of the United States of America 2009 IMEx Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Proceedings of the National Academy of Sciences of the United States of America 2009 imex curation Kline CF., Kurata HT., Hund TJ., Cunha SR., Koval OM., Wright PJ., Christensen M., Anderson ME., Nichols CG., Mohler PJ. Only protein-protein interactions mouse Mus musculus Mouse anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Kline CF., Kurata HT., Hund TJ., Cunha SR., Koval OM., Wright PJ., Christensen M., Anderson ME., Nichols CG., Mohler PJ. DIP original experiment: DIP-216474X Proceedings of the National Academy of Sciences of the United States of America 2009 IMEx Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Proceedings of the National Academy of Sciences of the United States of America 2009 imex curation Kline CF., Kurata HT., Hund TJ., Cunha SR., Koval OM., Wright PJ., Christensen M., Anderson ME., Nichols CG., Mohler PJ. Only protein-protein interactions human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip predetermined predetermined participant predetermined Kline CF., Kurata HT., Hund TJ., Cunha SR., Koval OM., Wright PJ., Christensen M., Anderson ME., Nichols CG., Mohler PJ. DIP original experiment: DIP-216465X Proceedings of the National Academy of Sciences of the United States of America 2009 IMEx Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Proceedings of the National Academy of Sciences of the United States of America 2009 imex curation Kline CF., Kurata HT., Hund TJ., Cunha SR., Koval OM., Wright PJ., Christensen M., Anderson ME., Nichols CG., Mohler PJ. Only protein-protein interactions in vitro In vitro pull down pull down autoradiography autoradiography Kline CF., Kurata HT., Hund TJ., Cunha SR., Koval OM., Wright PJ., Christensen M., Anderson ME., Nichols CG., Mohler PJ. DIP original experiment: DIP-216466X Proceedings of the National Academy of Sciences of the United States of America 2009 IMEx Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Proceedings of the National Academy of Sciences of the United States of America 2009 imex curation Kline CF., Kurata HT., Hund TJ., Cunha SR., Koval OM., Wright PJ., Christensen M., Anderson ME., Nichols CG., Mohler PJ. Only protein-protein interactions mouse Mus musculus Mouse anti bait coip anti bait coimmunoprecipitation anti bait coip predetermined predetermined participant predetermined Kline CF., Kurata HT., Hund TJ., Cunha SR., Koval OM., Wright PJ., Christensen M., Anderson ME., Nichols CG., Mohler PJ. DIP original experiment: DIP-216473X Proceedings of the National Academy of Sciences of the United States of America 2009 IMEx Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. p97582_rat protein protein rat Rattus norvegicus (Rat) Rat LRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGAYIQAITESGLTPIPVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGEVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGVTPLHLASQEGHTDMVTLVLEKGANIHMSTKSGLTSLHLAAEEDKVNVADILTKHGADQDAYTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEVTTTTTTITEKHKLNAPETMTEVLDVSDEEGDDTVTGDGGEYLRPEDLKELGDDSLPSS DIP protein P97582 original sequence version: 55 DC5A6AC78825D223 q09428-1 ATP-binding cassette sub-family C member 8 ABCC8 HRINS SUR SUR1 Sulfonylurea receptor 1 protein protein human Homo sapiens Human MPLAFCGSENHSAAYRVDQGVLNNGCFVDALNVVPHVFLLFITFPILFIGWGSQSSKVHIHHSTWLHFPGHNLRWILTFMLLFVLVCEIAEGILSDGVTESHHLHLYMPAGMAFMAAVTSVVYYHNIETSNFPKLLIALLVYWTLAFITKTIKFVKFLDHAIGFSQLRFCLTGLLVILYGMLLLVEVNVIRVRRYIFFKTPREVKPPEDLQDLGVRFLQPFVNLLSKGTYWWMNAFIKTAHKKPIDLRAIGKLPIAMRALTNYQRLCEAFDAQVRKDIQGTQGARAIWQALSHAFGRRLVLSSTFRILADLLGFAGPLCIFGIVDHLGKENDVFQPKTQFLGVYFVSSQEFLANAYVLAVLLFLALLLQRTFLQASYYVAIETGINLRGAIQTKIYNKIMHLSTSNLSMGEMTAGQICNLVAIDTNQLMWFFFLCPNLWAMPVQIIVGVILLYYILGVSALIGAAVIILLAPVQYFVATKLSQAQRSTLEYSNERLKQTNEMLRGIKLLKLYAWENIFRTRVETTRRKEMTSLRAFAIYTSISIFMNTAIPIAAVLITFVGHVSFFKEADFSPSVAFASLSLFHILVTPLFLLSSVVRSTVKALVSVQKLSEFLSSAEIREEQCAPHEPTPQGPASKYQAVPLRVVNRKRPAREDCRGLTGPLQSLVPSADGDADNCCVQIMGGYFTWTPDGIPTLSNITIRIPRGQLTMIVGQVGCGKSSLLLAALGEMQKVSGAVFWSSLPDSEIGEDPSPERETATDLDIRKRGPVAYASQKPWLLNATVEENIIFESPFNKQRYKMVIEACSLQPDIDILPHGDQTQIGERGINLSGGQRQRISVARALYQHANVVFLDDPFSALDIHLSDHLMQAGILELLRDDKRTVVLVTHKLQYLPHADWIIAMKDGTIQREGTLKDFQRSECQLFEHWKTLMNRQDQELEKETVTERKATEPPQGLSRAMSSRDGLLQDEEEEEEEAAESEEDDNLSSMLHQRAEIPWRACAKYLSSAGILLLSLLVFSQLLKHMVLVAIDYWLAKWTDSALTLTPAARNCSLSQECTLDQTVYAMVFTVLCSLGIVLCLVTSVTVEWTGLKVAKRLHRSLLNRIILAPMRFFETTPLGSILNRFSSDCNTIDQHIPSTLECLSRSTLLCVSALAVISYVTPVFLVALLPLAIVCYFIQKYFRVASRDLQQLDDTTQLPLLSHFAETVEGLTTIRAFRYEARFQQKLLEYTDSNNIASLFLTAANRWLEVRMEYIGACVVLIAAVTSISNSLHRELSAGLVGLGLTYALMVSNYLNWMVRNLADMELQLGAVKRIHGLLKTEAESYEGLLAPSLIPKNWPDQGKIQIQNLSVRYDSSLKPVLKHVNALIAPGQKIGICGRTGSGKSSFSLAFFRMVDTFEGHIIIDGIDIAKLPLHTLRSRLSIILQDPVLFSGTIRFNLDPERKCSDSTLWEALEIAQLKLVVKALPGGLDAIITEGGENFSQGQRQLFCLARAFVRKTSIFIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILSADLVIVLKRGAILEFDKPEKLLSRKDSVFASFVRADK DIP protein Q09428-1 original sequence version: 112 kcj11_human ATP-sensitive inward rectifier potassium channel 11 KCNJ11 IKATP Inward rectifier K(+) channel Kir6.2 Potassium channel, inwardly rectifying subfamily J member 11 protein protein human Homo sapiens Human MLSRKGIIPEEYVLTRLAEDPAEPRYRARQRRARFVSKKGNCNVAHKNIREQGRFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFAMAWWLIAFAHGDLAPSEGTAEPCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDLRKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANSPLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAEEDGRYSVDYSKFGNTIKVPTPLCTARQLDEDHSLLEALTLASARGPLRKRSVPMAKAKPKFSISPDSLS DIP protein Q14654 original sequence version: 117 8345E7DBCE897344 scn5a_human Sodium channel protein type 5 subunit alpha Sodium channel protein type V subunit alpha Voltage-gated sodium channel subunit alpha Nav1.5 Sodium channel protein cardiac muscle subunit alpha SCN5A hH1 protein protein human Homo sapiens Human MANFLLPRGTSSFRRFTRESLAAIEKRMAEKQARGSTTLQESREGLPEEEAPRPQLDLQASKKLPDLYGNPPQELIGEPLEDLDPFYSTQKTFIVLNKGKTIFRFSATNALYVLSPFHPIRRAAVKILVHSLFNMLIMCTILTNCVFMAQHDPPPWTKYVEYTFTAIYTFESLVKILARGFCLHAFTFLRDPWNWLDFSVIIMAYTTEFVDLGNVSALRTFRVLRALKTISVISGLKTIVGALIQSVKKLADVMVLTVFCLSVFALIGLQLFMGNLRHKCVRNFTALNGTNGSVEADGLVWESLDLYLSDPENYLLKNGTSDVLLCGNSSDAGTCPEGYRCLKAGENPDHGYTSFDSFAWAFLALFRLMTQDCWERLYQQTLRSAGKIYMIFFMLVIFLGSFYLVNLILAVVAMAYEEQNQATIAETEEKEKRFQEAMEMLKKEHEALTIRGVDTVSRSSLEMSPLAPVNSHERRSKRRKRMSSGTEECGEDRLPKSDSEDGPRAMNHLSLTRGLSRTSMKPRSSRGSIFTFRRRDLGSEADFADDENSTAGESESHHTSLLVPWPLRRTSAQGQPSPGTSAPGHALHGKKNSTVDCNGVVSLLGAGDPEATSPGSHLLRPVMLEHPPDTTTPSEEPGGPQMLTSQAPCVDGFEEPGARQRALSAVSVLTSALEELEESRHKCPPCWNRLAQRYLIWECCPLWMSIKQGVKLVVMDPFTDLTITMCIVLNTLFMALEHYNMTSEFEEMLQVGNLVFTGIFTAEMTFKIIALDPYYYFQQGWNIFDSIIVILSLMELGLSRMSNLSVLRSFRLLRVFKLAKSWPTLNTLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKNYSELRDSDSGLLPRWHMMDFFHAFLIIFRILCGEWIETMWDCMEVSGQSLCLLVFLLVMVIGNLVVLNLFLALLLSSFSADNLTAPDEDREMNNLQLALARIQRGLRFVKRTTWDFCCGLLRQRPQKPAALAAQGQLPSCIATPYSPPPPETEKVPPTRKETRFEEGEQPGQGTPGDPEPVCVPIAVAESDTDDQEEDEENSLGTEEESSKQQESQPVSGGPEAPPDSRTWSQVSATASSEAEASASQADWRQQWKAEPQAPGCGETPEDSCSEGSTADMTNTAELLEQIPDLGQDVKDPEDCFTEGCVRRCPCCAVDTTQAPGKVWWRLRKTCYHIVEHSWFETFIIFMILLSSGALAFEDIYLEERKTIKVLLEYADKMFTYVFVLEMLLKWVAYGFKKYFTNAWCWLDFLIVDVSLVSLVANTLGFAEMGPIKSLRTLRALRPLRALSRFEGMRVVVNALVGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFGRCINQTEGDLPLNYTIVNNKSQCESLNLTGELYWTKVKVNFDNVGAGYLALLQVATFKGWMDIMYAAVDSRGYEEQPQWEYNLYMYIYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKLGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPLNKYQGFIFDIVTKQAFDVTIMFLICLNMVTMMVETDDQSPEKINILAKINLLFVAIFTGECIVKLAALRHYYFTNSWNIFDFVVVILSIVGTVLSDIIQKYFFSPTLFRVIRLARIGRILRLIRGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYSIFGMANFAYVKWEAGIDDMFNFQTFANSMLCLFQITTSAGWDGLLSPILNTGPPYCDPTLPNSNGSRGDCGSPAVGILFFTTYIIISFLIVVNMYIAIILENFSVATEESTEPLSEDDFDMFYEIWEKFDPEATQFIEYSVLSDFADALSEPLRIAKPNQISLINMDLPMVSGDRIHCMDILFAFTKRVLGESGEMDALKIQMEEKFMAANPSKISYEPITTTLRRKHEEVSAMVIQRAFRRHLLQRSLKHASFLFRQQAGSGLSEEDAPEREGLIAYVMSENFSRPLGPPSSSSISSTSFPPSYDSVTRATSDNLQVRGSDYSHSEDLADFPPSPDRDRESIV DIP protein Q14524 original sequence version: 163 DIP protein Q14524 original sequence version: 119 DIP protein Q14524 original sequence version: 138 This sequence has been withdrawn from Uniprot. 841E3A365931190B kcj11_mouse ATP-sensitive inward rectifier potassium channel 11 Kcnj11 Inward rectifier K(+) channel Kir6.2 Potassium channel, inwardly rectifying subfamily J member 11 protein protein mouse Mus musculus Mouse MLSRKGIIPEEYVLTRLAEDPAEPRYRTRERRARFVSKKGNCNVAHKNIREQGRFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFAMVWWLIAFAHGDLAPGEGTNVPCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVITLRHGRLCFMLRVGDLRKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNGIFLVAPLIIYHVIDSNSPLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAEEDGRYSVDYSKFGNTIKVPTPLCTARQLDEDRSLLDALTLASSRGPLRKRSVAVAKAKPKFSISPDSLS DIP protein Q61743 original sequence version: 89 mint This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium 6AFBFFD284C92C3A kcj11_rat ATP-sensitive inward rectifier potassium channel 11 Kcnj11 BIR Inward rectifier K(+) channel Kir6.2 Potassium channel, inwardly rectifying subfamily J member 11 protein protein rat Rattus norvegicus (Rat) Rat MLSRKGIIPEEYVLTRLAEDPTEPRYRTRERRARFVSKKGNCNVAHKNIREQGRFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFAMVWWLIAFAHGDLAPGEGTNVPCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVITLRHGRLCFMLRVGDLRKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDSNSPLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAEEDGRYSVDYSKFGNTVKVPTPLCTARQLDEDRSLLDALTLASSRGPLRKRSVAVAKAKPKFSISPDSLS DIP protein P70673 original sequence version: 86 C8E59AD298DE4F13 ank3_human Ankyrin-3 Ankyrin-G ANK3 protein protein human Homo sapiens Human MAHAASQLKKNRDLEINAEEEPEKKRKHRKRSRDRKKKSDANASYLRAARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDTLKIVTEETMTTTTVTEKHKMNVPETMNEVLDMSDDEVRKANAPEMLSDGEYISDVEEGEDAMTGDTDKYLGPQDLKELGDDSLPAEGYMGFSLGARSASLRSFSSDRSYTLNRSSYARDSMMIEELLVPSKEQHLTFTREFDSDSLRHYSWAADTLDNVNLVSSPIHSGFLVSFMVDARGGSMRGSRHHGMRIIIPPRKCTAPTRITCRLVKRHKLANPPPMVEGEGLASRLVEMGPAGAQFLGPVIVEIPHFGSMRGKERELIVLRSENGETWKEHQFDSKNEDLTELLNGMDEELDSPEELGKKRICRIITKDFPQYFAVVSRIKQESNQIGPEGGILSSTTVPLVQASFPEGALTKRIRVGLQAQPVPDEIVKKILGNKATFSPIVTVEPRRRKFHKPITMTIPVPPPSGEGVSNGYKGDTTPNLRLLCSITGGTSPAQWEDITGTTPLTFIKDCVSFTTNVSARFWLADCHQVLETVGLATQLYRELICVPYMAKFVVFAKMNDPVESSLRCFCMTDDKVDKTLEQQENFEEVARSKDIEVLEGKPIYVDCYGNLAPLTKGGQQLVFNFYSFKENRLPFSIKIRDTSQEPCGRLSFLKEPKTTKGLPQTAVCNLNITLPAHKKETESDQDDEIEKTDRRQSFASLALRKRYSYLTEPGMIERSTGATRSLPTTYSYKPFFSTRPYQSWTTAPITVPGPAKSGFTSLSSSSSNTPSASPLKSIWSVSTPSPIKSTLGASTTSSVKSISDVASPIRSFRTMSSPIKTVVSQSPYNIQVSSGTLARAPAVTEATPLKGLASNSTFSSRTSPVTTAGSLLERSSITMTPPASPKSNINMYSSSLPFKSIITSAAPLISSPLKSVVSPVKSAVDVISSAKITMASSLSSPVKQMPGHAEVALVNGSISPLKYPSSSTLINGCKATATLQEKISSATNSVSSVVSAATDTVEKVFSTTTAMPFSPLRSYVSAAPSAFQSLRTPSASALYTSLGSSISATTSSVTSSIITVPVYSVVNVLPEPALKKLPDSNSFTKSAAALLSPIKTLTTETHPQPHFSRTSSPVKSSLFLAPSALKLSTPSSLSSSQEILKDVAEMKEDLMRMTAILQTDVPEEKPFQPELPKEGRIDDEEPFKIVEKVKEDLVKVSEILKKDVCVDNKGSPKSPKSDKGHSPEDDWIEFSSEEIREARQQAAASQSPSLPERVQVKAKAASEKDYNLTKVIDYLTNDIGSSSLTNLKYKFEDAKKDGEERQKRVLKPAIALQEHKLKMPPASMRTSTSEKELCKMADSFFGTDTILESPDDFSQHDQDKSPLSDSGFETRSEKTPSAPQSAESTGPKPLFHEVPIPPVITETRTEVVHVIRSYDPSAGDVPQTQPEEPVSPKPSPTFMELEPKPTTSSIKEKVKAFQMKASSEEDDHNRVLSKGMRVKEETHITTTTRMVYHSPPGGEGASERIEETMSVHDIMKAFQSGRDPSKELAGLFEHKSAVSPDVHKSAAETSAQHAEKDNQMKPKLERIIEVHIEKGNQAEPTEVIIRETKKHPEKEMYVYQKDLSRGDINLKDFLPEKHDAFPCSEEQGQQEEEELTAEESLPSYLESSRVNTPVSQEEDSRPSSAQLISDDSYKTLKLLSQHSIEYHDDELSELRGESYRFAEKMLLSEKLDVSHSDTEESVTDHAGPPSSELQGSDKRSREKIATAPKKEILSKIYKDVSENGVGKVSKDEHFDKVTVLHYSGNVSSPKHAMWMRFTEDRLDRGREKLIYEDRVDRTVKEAEEKLTEVSQFFRDKTEKLNDELQSPEKKARPKNGKEYSSQSPTSSSPEKVLLTELLASNDEWVKARQHGPDGQGFPKAEEKAPSLPSSPEKMVLSQQTEDSKSTVEAKGSISQSKAPDGPQSGFQLKQSKLSSIRLKFEQGTHAKSKDMSQEDRKSDGQSRIPVKKIQESKLPVYQVFAREKQQKAIDLPDESVSVQKDFMVLKTKDEHAQSNEIVVNDSGSDNVKKQRTEMSSKAMPDSFSEQQAKDLACHITSDLATRGPWDKKVFRTWESSGATNNKSQKEKLSHVLVHDVRENHIGHPESKSVDQKNEFMSVTERERKLLTNGSLSEIKEMTVKSPSKKVLYREYVVKEGDHPGGLLDQPSRRSESSAVSHIPVRVADERRMLSSNIPDGFCEQSAFPKHELSQKLSQSSMSKETVETQHFNSIEDEKVTYSEISKVSKHQSYVGLCPPLEETETSPTKSPDSLEFSPGKESPSSDVFDHSPIDGLEKLAPLAQTEGGKEIKTLPVYVSFVQVGKQYEKEIQQGGVKKIISQECKTVQETRGTFYTTRQQKQPPSPQGSPEDDTLEQVSFLDSSGKSPLTPETPSSEEVSYEFTSKTPDSLIAYIPGKPSPIPEVSEESEEEEQAKSTSLKQTTVEETAVEREMPNDVSKDSNQRPKNNRVAYIEFPPPPPLDADQIESDKKHHYLPEKEVDMIEVNLQDEHDKYQLAEPVIRVQPPSPVPPGADVSDSSDDESIYQPVPVKKYTFKLKEVDDEQKEKPKASAEKASNQKELESNGSGKDNEFGLGLDSPQNEIAQNGNNDQSITECSIATTAEFSHDTDATEIDSLDGYDLQDEDDGLTESDSKLPIQAMEIKKDIWNTEGILKPADRSFSQSKLEVIEEEGKVGPDEDKPPSKSSSSEKTPDKTDQKSGAQFFTLEGRHPDRSVFPDTYFSYKVDEEFATPFKTVATKGLDFDPWSNNRGDDEVFDSKSREDETKPFGLAVEDRSPATTPDTTPARTPTDESTPTSEPNPFPFHEGKMFEMTRSGAIDMSKRDFVEERLQFFQIGEHTSEGKSGDQGEGDKSMVTATPQPQSGDTTVETNLERNVETPTVEPNPSIPTSGECQEGTSSSGSLEKSAAATNTSKVDPKLRTPIKMGISASTMTMKKEGPGEITDKIEAVMTSCQGLENETITMISNTANSQMGVRPHEKHDFQKDNFNNNNNLDSSTIQTDNIMSNIVLTEHSAPTCTTEKDNPVKVSSGKKTGVLQGHCVRDKQKVLGEQQKTKELIGIRQKSKLPIKATSPKDTFPPNHMSNTKASKMKQVSQSEKTKALTTSSCVDVKSRIPVKNTHRDNIIAVRKACATQKQGQPEKGKAKQLPSKLPVKVRSTCVTTTTTTATTTTTTTTTTTTSCTVKVRKSQLKEVCKHSIEYFKGISGETLKLVDRLSEEEKKMQSELSDEEESTSRNTSLSETSRGGQPSVTTKSARDKKTEAAPLKSKSEKAGSEKRSSRRTGPQSPCERTDIRMAIVADHLGLSWTELARELNFSVDEINQIRVENPNSLISQSFMLLKKWVTRDGKNATTDALTSVLTKINRIDIVTLLEGPIFDYGNISGTRSFADENNVFHDPVDGWQNETSSGNLESCAQARRVTGGLLDRLDDSPDQCRDSITSYLKGEAGKFEANGSHTEITPEAKTKSYFPESQNDVGKQSTKETLKPKIHGSGHVEEPASPLAAYQKSLEETSKLIIEETKPCVPVSMKKMSRTSPADGKPRLSLHEEEGSSGSEQKQGEGFKVKTKKEIRHVEKKSHS DIP protein Q12955 original sequence version: 96 DIP protein Q12955 original sequence version: 94 F6F9FABD09F15C13 ank2_human Ankyrin-2 ANKB ANK2 Brain ankyrin Ankyrin-B Non-erythroid ankyrin protein protein human Homo sapiens Human MMNEDAAQKSDSGEKFNGSSQRRKRPKKSDSNASFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEVTTTTTTITEKHKLNVPETMTEVLDVSDEEGDDTMTGDGGEYLRPEDLKELGDDSLPSSQFLDGMNYLRYSLEGGRSDSLRSFSSDRSHTLSHASYLRDSAVMDDSVVIPSHQVSTLAKEAERNSYRLSWGTENLDNVALSSSPIHSGFLVSFMVDARGGAMRGCRHNGLRIIIPPRKCTAPTRVTCRLVKRHRLATMPPMVEGEGLASRLIEVGPSGAQFLGKLHLPTAPPPLNEGESLVSRILQLGPPGTKFLGPVIVEIPHFAALRGKERELVVLRSENGDSWKEHFCDYTEDELNEILNGMDEVLDSPEDLEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVPQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATFSPIVTLEPRRRKFHKPITMTIPVPKASSDVMLNGFGGDAPTLRLLCSITGGTTPAQWEDITGTTPLTFVNECVSFTTNVSARFWLIDCRQIQESVTFASQVYREIICVPYMAKFVVFAKSHDPIEARLRCFCMTDDKVDKTLEQQENFAEVARSRDVEVLEGKPIYVDCFGNLVPLTKSGQHHIFSFFAFKENRLPLFVKVRDTTQEPCGRLSFMKEPKSTRGLVHQAICNLNITLPIYTKESESDQEQEEEIDMTSEKNDETESTETSVLKSHLVNEVPVLASPDLLSEVSEMKQDLIKMTAILTTDVSDKAGSIKVKELVKAAEEEPGEPFEIVERVKEDLEKVNEILRSGTCTRDESSVQSSRSERGLVEEEWVIVSDEEIEEARQKAPLEITEYPCVEVRIDKEIKGKVEKDSTGLVNYLTDDLNTCVPLPKEQLQTVQDKAGKKCEALAVGRSSEKEGKDIPPDETQSTQKQHKPSLGIKKPVRRKLKEKQKQKEEGLQASAEKAELKKGSSEESLGEDPGLAPEPLPTVKATSPLIEETPIGSIKDKVKALQKRVEDEQKGRSKLPIRVKGKEDVPKKTTHRPHPAASPSLKSERHAPGSPSPKTERHSTLSSSAKTERHPPVSPSSKTEKHSPVSPSAKTERHSPASSSSKTEKHSPVSPSTKTERHSPVSSTKTERHPPVSPSGKTDKRPPVSPSGRTEKHPPVSPGRTEKRLPVSPSGRTDKHQPVSTAGKTEKHLPVSPSGKTEKQPPVSPTSKTERIEETMSVRELMKAFQSGQDPSKHKTGLFEHKSAKQKQPQEKGKVRVEKEKGPILTQREAQKTENQTIKRGQRLPVTGTAESKRGVRVSSIGVKKEDAAGGKEKVLSHKIPEPVQSVPEEESHRESEVPKEKMADEQGDMDLQISPDRKTSTDFSEVIKQELEDNDKYQQFRLSEETEKAQLHLDQVLTSPFNTTFPLDYMKDEFLPALSLQSGALDGSSESLKNEGVAGSPCGSLMEGTPQISSEESYKHEGLAETPETSPESLSFSPKKSEEQTGETKESTKTETTTEIRSEKEHPTTKDITGGSEERGATVTEDSETSTESFQKEATLGSPKDTSPKRQDDCTGSCSVALAKETPTGLTEEAACDEGQRTFGSSAHKTQTDSEVQESTATSDETKALPLPEASVKTDTGTESKPQGVIRSPQGLELALPSRDSEVLSAVADDSLAVSHKDSLEASPVLEDNSSHKTPDSLEPSPLKESPCRDSLESSPVEPKMKAGIFPSHFPLPAAVAKTELLTEVASVRSRLLRDPDGSAEDDSLEQTSLMESSGKSPLSPDTPSSEEVSYEVTPKTTDVSTPKPAVIHECAEEDDSENGEKKRFTPEEEMFKMVTKIKMFDELEQEAKQKRDYKKEPKQEESSSSSDPDADCSVDVDEPKHTGSGEDESGVPVLVTSESRKVSSSSESEPELAQLKKGADSGLLPEPVIRVQPPSPLPSSMDSNSSPEEVQFQPVVSKQYTFKMNEDTQEEPGKSEEEKDSESHLAEDRHAVSTEAEDRSYDKLNRDTDQPKICDGHGCEAMSPSSSAAPVSSGLQSPTGDDVDEQPVIYKESLALQGTHEKDTEGEELDVSRAESPQADCPSESFSSSSSLPHCLVSEGKELDEDISATSSIQKTEVTKTDETFENLPKDCPSQDSSITTQTDRFSMDVPVSDLAENDEIYDPQITSPYENVPSQSFFSSEESKTQTDANHTTSFHSSEVYSVTITSPVEDVVVASSSSGTVLSKESNFEGQDIKMESQQESTLWEMQSDSVSSSFEPTMSATTTVVGEQISKVIITKTDVDSDSWSEIREDDEAFEARVKEEEQKIFGLMVDRQSQGTTPDTTPARTPTEEGTPTSEQNPFLFQEGKLFEMTRSGAIDMTKRSYADESFHFFQIGQESREETLSEDVKEGATGADPLPLETSAESLALSESKETVDDEADLLPDDVSEEVEEIPASDAQLNSQMGISASTETPTKEAVSVGTKDLPTVQTGDIPPLSGVKQISCPDSSEPAVQVQLDFSTLTRSVYSDRGDDSPDSSPEEQKSVIEIPTAPMENVPFTESKSKIPVRTMPTSTPAPPSAEYESSVSEDFLSSVDEENKADEAKPKSKLPVKVPLQRVEQQLSDLDTSVQKTVAPQGQDMASIAPDNRSKSESDASSLDSKTKCPVKTRSYTETETESRERAEELELESEEGATRPKILTSRLPVKSRSTTSSCRGGTSPTKESKEHFFDLYRNSIEFFEEISDEASKLVDRLTQSEREQEIVSDDESSSALEVSVIENLPPVETEHSVPEDIFDTRPIWDESIETLIERIPDENGHDHAEDPQDEQERIEERLAYIADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWLERDGKHATDTNLVECLTKINRMDIVHLMETNTEPLQERISHSYAEIEQTITLDHSEGFSVLQEELCTAQHKQKEEQAVSKESETCDHPPIVSEEDISVGYSTFQDGVPKTEGDSSATALFPQTHKEQVQQDFSGKMQDLPEESSLEYQQEYFVTTPGTETSETQKAMIVPSSPSKTPEEVSTPAEEEKLYLQTPTSSERGGSPIIQEPEEPSEHREESSPRKTSLVIVESADNQPETCERLDEDAAFEKGDDMPEIPPETVTEEEYIDEHGHTVVKKVTRKIIRRYVSSEGTEKEEIMVQGMPQEPVNIEEGDGYSKVIKRVVLKSDTEQSEDNNE DIP protein Q01484 original sequence version: 113 41C1A240CC5A3B72 b2rus7_mouse Abcc8 protein protein mouse Mus musculus Mouse MPLAFCGTENHSAAYRVDQGVLNNGCFVDALNVVPHVFLLFITFPILFIGWGSQSSKVHIHHSTWLHFPGHNLRWILTFMLLFVLVCEIAEGILSDGVTESRHLHLYMPAGMAFMAAITSVVYYHNIETSNFPKLLIALLIYWTLAFITKTIKFVKFYDHAIGFSQLRFCLTGLLVILYGMLLLVEINVIRVRRYIFFKTPREVKPPEDLQDLGVRFLQPFVNLLSKGTYWWMNAFIKTAHRKPIDLRAIGKLPIAMRALTNYQRLCAAFDAQARKDTQSQQGARAIWRALCHAFGRRLVLSSTFRILADLLGFAGPLCIFGIVDHLGKENHVFQPKTQFLGVYFVSSQEFLGNAYVLAVLLFLALLLQRTFLQASYYVAIETGINLRGAIQTKIYNKIMHLSTSNLSMGEMTAGQICNLVAIDTNQLMWFFFLCPNLWAMPVQIIVGVILLYYILGVSALIGAAVIILLAPVQYFVATKLSQAQRSTLEYSNERLKQTNEMLRGIKLLKLYAWENIFCSRVEMTRRKEMTSLRAFAVYTSISIFMNTAIPIAAVLITFVGHVSFFKESDFSPSVAFASLSLFHILVTPLFLLSSVVRSTVKALVSVQKLSEFLSSAEIREEQCAPREPAPQGQAGKYQAVPLKVVNRKRPAREEVRDLLGPLQRLTPSMDGDADNFCVQIIGGFFTWTPDGIPTLSNITIRIPRGQLTMIVGQVGCGKSSLLLATLGEMQRVSGAVFWNSSLPDSEGEDPRYCLRTSNPERETAADSDARSRGPVAYASQKPWLLNATVEENITFESPFNKQRYKMVIEACSLQPDIDILPHGDQTQIGERGINLSGGQRQRISVARALYQHTNVVFLDDPFSALDVHLSDHLMQAGILELLRDDKRTVVLVTHKLQYLPHADWIIAMKDGTIQREGTLKDFQRSECQLFEHWKTLMNRQDQELEKETVMERKAPEPSQGLPRAMSSRDGLLLDEDEEEEEAAESEEDDNLSSVLHQRAKIPWRACTKYLSSAGVLLLSLLVFSQLLKHMVLVAIDYWLAKWTDSALVLSPAARNCSLSQECALDQSVYAMVFTVLCSLGIALCLVTSVTVEWTGLKVAKRLHRSLLNRIILAPMRFFETTPLGSILNRFSSDCNTIDQHIPSTLECLSRSTLLCVSALTVISYVTPVFLVALLPLAVVCYFIQKYFRVASRDLQQLDDTTQLPLLSHFAETVEGLTTIRAFRYEARFQQKLLEYTDSNNIASLFLTAANRWLEVRMEYIGACVVLIAAATSISNSLHRELSAGLVGLGLTYALMVSNYLNWMVRNLADMEIQLGAVKRIHTLLKTEAESYEGLLAPSLIPKNWPDQGKIQIQNLSVRYDSSLKPVLKHVNALIAPGQKIGICGRTGSGKSSFSLAFFRMVDMFEGRIIIDGIDIAKLPLHTLRSRLSIILQDPVLFSGTIRFNLDPEKKCSDSTLWEALEIAQLKLVVKALPGGLDAIITEGGENFSQGQRQLFCLARAFVRKTSIFIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILSADLVMVLKRGAILEFDKPEKLLSQKDSVFASFVRADK DIP protein B2RUS7 original sequence version: 27 661159D6319EFD53 ank2_mouse Ankyrin-2 Brain ankyrin AnkB Ank2 Ankyrin-B protein protein mouse Mus musculus Mouse MMNEDAAQKSDSGEKFNGSSQRRKRPKKSDSNASFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERKAPLLARTKNGLSPLHMAAQGDHVECVKHLLQYKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADRDAYTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEVTTTTTTITEKHKLNVPETMTEVLDVSDEEGDDTVTGDGGEYLRPEDLKELGDDSLPSSQFLDGMNYLRYSLEGGRSDSLRSFSSDRSHTLSHASYLRDSAMIDDTVVIPSHQVSALAKEAERNSYRLSWGTENLDNVALSSSPIHSGFLVSFMVDARGGAMRGCRHNGLRIIIPPRKCTAPTRVTCRLVKRHRLATMPPMVEGEGLASRLIEVGPSGAQFLGPVIVEIPHFAALRGKERELVVLRSENGDSWKEHFCDYTEDELNEILNGMDEVLDSPEDLEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVSQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATFSPIVTLEPRRRKFHKPITMTIPVPKASSDVMLNGFGGDAPTLRLLCSITGGTTPAQWEDITGTTPLTFVNECVSFTTNVSARFWLIDCRQIQESVAFASQVYREIICVPYMAKFVVFAKSHDPIEARLRCFCMTDDKVDKTLEQQENFSEVARSRDVEVLEGKPIYVDCFGNLVPLTKSGQHHIFSFFAFKENRLPLFVKVRDTTQEPCGRLSFMKEPKSTRGLVHQAICNLNITLPIYAKESESDQEPEEEIGMTSEKNDETESTETSVLKSHLVNEVPVLASPDLLSEVSEMKQDLIKMTAILTTDVSDKAGSLKVKELAKAGEEEPGEPFEIVERVKEDLEKVNAILRSGTCMRDEGRARSSQSERELEEEWVIVSDEEIQEAKQHAPVEIDEHPCIEVRVDRETKAKVEKDSTGLVNYLTDDLNSYTSPHEKKPHTAPEKSGETSQASAVGKSSESNKGKATSAEEKQSAQKQLKPGLAIKKPVRRKLKEKQKQKEESSQSSEEKTELKKGSSEESVDEDRGLVPEPLPTAKATSPLIEETPIGSIKDKVKALQKRVEDEQKGRSKLPVRVKGKEDVPKRTTPRTHPAVSPSSKSSTSSKAERHSSLSSSAKPERHTPVSPSSKNEKLSPVSPSAKTERHSPVFSGKPEKHSPGSPSTKNERHSPVSSLKTERHTPGSPSGKTDKRPPVPSSGRTEKHPPVSPGKTEKHLPGSPSIRTPEKPAPGSATGKHEKHLPVSPGKTEKQPPISPTSKTERIEETMSVRELMKAFQSGQDPSKHKTGLFEHKSAKQKQPQDKSKSRVEKEKGHTVTQREVTQRETQRIESQTAKRGQRFQVSAATESRRFRSTTITVGLRMEDPVRERFERTPIIKTPEVVPSVAAEESHRGSEKIVDEQGDMDFQISPDRKTSTDFSEVIKQELEDNDKYQQFRLTEDTEKAQVHLDQVITSPFNTAFPLDYMKDEFLPALSLQSGALGGSSESLKQEVIAGSPCSSLMEGTPQISSEESYKHEGLAETPETSPESLSFSPKKSEEQIGEAKETTKVGTPTDIHSEKELPITNDITDSSQKQGAGVTRGSEPSTEHSQKEVTQDPHKDVCSKQDGCPESQSVSLASEVFTEKGSCGESQLPLVSSAFKTQSESETQESLTPSEVTKPFPPSDASVKTAEGTEPKPQGAIRSPQGLELPLPNRDSEVLSPMADESLAVSHKDSLEASPVLEDNSSHKTPDSLEPSPLKESPCRDSLESSPVEPKMKAGILPSHFPLPAAIAKTDLVAEVASMRSRLLRDPDGSAEDDSLEQTSLMESSGKSPLSPDTPSSEEVSYEVTPKPSDSSTPKPAVIHECAEEDDSENGEKKRFTPEEEMFKMVTKIKTFDELEQEAKQKRDYKKEPRQDGSSSASDPDADYSAEVNDEKQMAGTEGEGEVPVLVTSENRKVSSSSSESEPELTQLSKGADSGLLTEPVIRVQPPSPLPSSIDSNSSPEEATQFQPIVPKQYTFKMNEEIQEEPATSEDKDCKSHLAEDSQTHSADAADGSDGDLNRETTQPETCDGHGCETVSPSNSATPVSLGVQSPEHKDVDKPLAIDKDSLAHQDTCENDREEREFDPSGVESTQADLPNESSSLSSRCAIPEGNESAKEIASPSSPVKVEVTITDQALESMPEDCPIQDSSTTMQTERFAMDVPVSELAETDENSDPQIISPYENVPSSSFFSAEPSKIQTDTCHSTVVHSPEVYSVIIRSSPEDVVVTNSSNRTVSGEESHCESHDLETESEQKSALWAAQSDAPPLAVAPTASDAASVTGEQASKVIITKTDADADSWSEIREDDAAFEARVKEEEQKIFGLMVDRQSQGTTPDTTPARTPTEEGTPTSEQNPFLFQEGKLFEMTRSGAIDMTKRPYADESLHFFQIGQESNEEAISEDLKEGATGAEPPQTETTSESLELSEPKEAMDDEGELLPDDVSEEIEDLPASDANIDSQVIISASTETPTKEAVSTAVEEPPTTQRSDSLSTVKQTPRPAVPGPVGQLDFSPVTRSVYSGQDDESPESSPEEQKSVIEIPTAPVDNVPSAESKPQIPIRTLPTLVPAPPSAEDESAFSDDFPSSLDEDSKEGGAKPKSKIPVKAPTQRTEWQPSPTDIPLQKTAVPQGQETLSRAPDGRSKSESDASSLDAKTKCPVKARSYIETETESRERAEGFESESEDGATKPKLFASRLPVKSRSTSSSGRPGTSPTRESREHFFDLYRNSIEFFEEISDEASKLVDRLTQSEREQEPPSDDESSSALEVSVIESLPPVDIEHSAPEDIFDTRPIWDESIETMIERIPDENGHDRAEDPQDEQERMEERLAYIADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWLERDGKHATDTILIECLTKINRMDIVHLLETNTEPLQERMGRSYAEIEQTITLDHSEGFSVLPDELCAAKEKKEQEASKESESSDHPPMVSEEDISVGYSTFQDCLPKTEGDSPAAALSPQMHQEPVQQDFSGKTQDQQEYYVTTPGAEVEDPQKATAVPDSLCKTPEDISTPPEGTKPCLQTPVTSERGSPIVQEPEEASEPKEESSPRKTSLVIVESTDDQSQVFERLDGDAAFQKGDDMPDIPPETVTEEEYVDENGHTVVKKVTRKIIRRYVSSDGTEKEEVTMQGMPQEPVNIEDGDNYSKVIKRVVLKSDTQQSEDNNE DIP protein Q8C8R3 original sequence version: 58 A779A20AA489DB34 ank2-kcnj11-1 5 19 unspecified role unspecified role prey prey rat Rattus norvegicus (Rat) Rat 14 unspecified role unspecified role bait bait rat Rattus norvegicus (Rat) Rat physical association physical association kcnj11-ank2-1 12 21 unspecified role unspecified role prey prey 35S-label 35S-label 35s radiolabel 35s radiolabel 35S s35 radiolabelled S35 s35 radiolabelled 35S S35 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Region 1-861 Region 1-861 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain in vitro In vitro 16 unspecified role unspecified role bait bait Region 313-325 Region 313-325 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain Biotin-tag Biotin-tag biotin tag biotin tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range Q14654:p.Glu322Lys E322K mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain E K This feature has been corrected as a result of our quality control procedures. The original label was 'E322K'. Wed May 02 16:28:44 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'glu322lys' Tue Jun 30 19:04:03 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Glu322Lys' in vitro In vitro direct interaction direct interaction ank2-kcnj11-2 3 21 unspecified role unspecified role bait bait Membrane-binding domain Region 1-861 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecolx Escherichia coli 16 unspecified role unspecified role prey prey 35S-label 35S-label 35s radiolabel 35s radiolabel 35S s35 radiolabelled S35 s35 radiolabelled 35S S35 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Region 1-330 Region 1-330 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain Q14654:p.Glu321Lys E321K mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain E K This feature has been corrected as a result of our quality control procedures. The original label was 'E321K'. Wed May 02 16:57:27 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'glu321lys' Tue Jun 30 20:16:16 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Glu321Lys' Q14654:p.Glu322Lys E322K mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain E K This feature has been corrected as a result of our quality control procedures. The original label was 'E322K'. Wed May 02 17:41:01 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'glu322lys' Tue Jun 30 19:05:43 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Glu322Lys' Q14654:p.Asp323Lys D323K mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain D K This feature has been corrected as a result of our quality control procedures. The original label was 'D323K'. Wed May 02 15:30:33 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'asp323lys' Tue Jun 30 19:00:26 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Asp323Lys' in vitro In vitro direct interaction direct interaction ank2-abcc8-1 10 22 unspecified role unspecified role prey prey mouse Mus musculus Mouse 23 unspecified role unspecified role bait bait mouse Mus musculus Mouse physical association physical association kcnj11-abcc8-1 6 18 unspecified role unspecified role bait bait mouse Mus musculus Mouse 22 unspecified role unspecified role prey prey human Homo sapiens Human physical association physical association ank2-kcnj11-3 7 21 unspecified role unspecified role bait bait human Homo sapiens Human 16 unspecified role unspecified role prey prey Q14654:p.Glu322Lys E322K mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain E K This feature has been corrected as a result of our quality control procedures. The original label was 'E322K'. Wed May 02 14:49:31 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'glu322lys' Tue Jun 30 18:49:49 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Glu322Lys' human Homo sapiens Human physical association physical association kcnj11-ank2-2 1 18 unspecified role unspecified role bait bait mouse Mus musculus Mouse 23 unspecified role unspecified role prey prey mouse Mus musculus Mouse physical association physical association kcnj11-ank2-3 4 21 unspecified role unspecified role prey prey human Homo sapiens Human 16 unspecified role unspecified role bait bait Q14654:p.Glu322Lys E322K mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain E K This feature has been corrected as a result of our quality control procedures. The original label was 'E322K'. Wed May 02 15:45:24 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'glu322lys' Tue Jun 30 16:41:21 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Glu322Lys' human Homo sapiens Human physical association physical association ank3-scn5a-1 9 20 unspecified role unspecified role bait bait Membrane-binding domain Region 1-886 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecolx Escherichia coli 17 unspecified role unspecified role prey prey Q14524:p.Glu1053Lys E1053K mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain E K This feature has been corrected as a result of our quality control procedures. The original label was 'E1053K'. Wed May 02 16:48:29 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'glu1053lys' Tue Jun 30 19:40:56 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Glu1053Lys' 35S-label 35S-label 35s radiolabel 35s radiolabel 35S s35 radiolabelled S35 s35 radiolabelled 35S S35 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined DII-DIII loop domain Region 1047-1055 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain in vitro In vitro direct interaction direct interaction kcnj11-abcc8-2 2 16 unspecified role unspecified role bait bait human Homo sapiens Human 15 unspecified role unspecified role prey prey human Homo sapiens Human physical association physical association ank2-abcc8-2 8 21 unspecified role unspecified role bait bait human Homo sapiens Human 16 unspecified role unspecified role prey prey Q14654:p.Glu322Lys E322K mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain E K This feature has been corrected as a result of our quality control procedures. The original label was 'E322K'. Wed May 02 16:19:37 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'glu322lys' Tue Jun 30 16:57:46 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Glu322Lys' human Homo sapiens Human 15 unspecified role unspecified role prey prey human Homo sapiens Human association association kcnj11-abcc8-3 11 21 unspecified role unspecified role prey prey human Homo sapiens Human 16 unspecified role unspecified role bait bait human Homo sapiens Human 15 unspecified role unspecified role prey prey human Homo sapiens Human association association ank2-kcnj11-4 13 18 unspecified role unspecified role prey prey mouse Mus musculus Mouse 23 unspecified role unspecified role bait bait mouse Mus musculus Mouse physical association physical association