DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu SDH5, a gene required for flavination of succinate dehydrogenase, is mutated in paraganglioma. SDH5, a gene required for flavination of succinate dehydrogenase, is mutated in paraganglioma. Science (New York, N.Y.) 2009 imex curation Hao HX., Khalimonchuk O., Schraders M., Dephoure N., Bayley JP., Kunst H., Devilee P., Cremers CW., Schiffman JD., Bentz BG., Gygi SP., Winge DR., Kremer H., Rutter J. Only protein-protein interactions yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast tap tandem affinity purification TAP TAP tap western blot western blot Immuno blot Immuno blot Hao HX., Khalimonchuk O., Schraders M., Dephoure N., Bayley JP., Kunst H., Devilee P., Cremers CW., Schiffman JD., Bentz BG., Gygi SP., Winge DR., Kremer H., Rutter J. DIP original experiment: DIP-266797X Science (New York, N.Y.) 2009 IMEx SDH5, a gene required for flavination of succinate dehydrogenase, is mutated in paraganglioma. SDH5, a gene required for flavination of succinate dehydrogenase, is mutated in paraganglioma. SDH5, a gene required for flavination of succinate dehydrogenase, is mutated in paraganglioma. Science (New York, N.Y.) 2009 imex curation Hao HX., Khalimonchuk O., Schraders M., Dephoure N., Bayley JP., Kunst H., Devilee P., Cremers CW., Schiffman JD., Bentz BG., Gygi SP., Winge DR., Kremer H., Rutter J. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Hao HX., Khalimonchuk O., Schraders M., Dephoure N., Bayley JP., Kunst H., Devilee P., Cremers CW., Schiffman JD., Bentz BG., Gygi SP., Winge DR., Kremer H., Rutter J. DIP original experiment: DIP-266798X Science (New York, N.Y.) 2009 IMEx SDH5, a gene required for flavination of succinate dehydrogenase, is mutated in paraganglioma. sdha_yeast Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial SDH1 SDHA YKL148C YKL602 Flavoprotein subunit of complex II protein protein yeast Saccharomyces cerevisiae Baker's yeast MLSLKKSALSKLTLLRNTRTFTSSALVRQTQGSVNGSASRSADGKYHIIDHEYDCVVIGAGGAGLRAAFGLAEAGYKTACISKLFPTRSHTVAAQGGINAALGNMHKDNWKWHMYDTVKGSDWLGDQDSIHYMTREAPKSIIELEHYGVPFSRTENGKIYQRAFGGQTKEYGKGAQAYRTCAVADRTGHALLHTLYGQALRHDTHFFIEYFALDLLTHNGEVVGVIAYNQEDGTIHRFRAHKTIIATGGYGRAYFSCTSAHTCTGDGNAMVSRAGFPLQDLEFVQFHPSGIYGSGCLITEGARGEGGFLVNSEGERFMERYAPTAKDLACRDVVSRAITMEIREGRGVGKKKDHMYLQLSHLPPEVLKERLPGISETAAIFAGVDVTKEPIPIIPTVHYNMGGIPTKWNGEALTIDEETGEDKVIPGLMACGEAACVSVHGANRLGANSLLDLVVFGRAVAHTVADTLQPGLPHKPLPSDLGKESIANLDKLRNANGSRSTAEIRMNMKQTMQKDVSVFRTQSSLDEGVRNITAVEKTFDDVKTTDRSMIWNSDLVETLELQNLLTCASQTAVSAANRKESRGAHAREDYPNRDDEHWMKHTLSWQKDVAAPVTLKYRRVIDHTLDEKECPSVPPTVRAY A657E440B8ED58E2 A657E440B8ED58E2 sdhf2_yeast Succinate dehydrogenase assembly factor 2, mitochondrial SDH5 EMI5 YOL071W protein protein yeast Saccharomyces cerevisiae Baker's yeast MHNMFPALTKTLSLQGYKIINSQTGSAAWSCGRRWFSSDKDDHDDVVTRIKIAPIKRTNEPLDKKRARLIYQSRKRGILETDLLLSGFAAKYLKKMNEEELEEYDSLLNELDWDIYYWATKNFKTSPLPDKWANSKLLKQLQEFSENKEKEILSMPDLSKYQ 8CDF8E943D46A12D sdha_human Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial SDHA SDH2 SDHF Flavoprotein subunit of complex II protein protein human Homo sapiens Human MSGVRGLSRLLSARRLALAKAWPTVLQTGTRGFHFTVDGNKRASAKVSDSISAQYPVVDHEFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNWRWHFYDTVKGSDWLGDQDAIHYMTEQAPAAVVELENYGMPFSRTEDGKIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIEDGSIHRIRAKNTVVATGGYGRTYFSCTSAHTSTGDGTAMITRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGCGPEKDHVYLQLHHLPPEQLATRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVLRHVNGQDQIVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIEESCRPGDKVPPIKPNAGEESVMNLDKLRFADGSIRTSELRLSMQKSMQNHAAVFRVGSVLQEGCGKISKLYGDLKHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKVRIDEYDYSKPIQGQQKKPFEEHWRKHTLSYVDVGTGKVTLEYRPVIDKTLNEADCATVPPAIRSY DIP protein P31040 original sequence version: 196 DIP protein P31040 original sequence version: 181 180B664E3FFD0B34 sdhf2_human Succinate dehydrogenase assembly factor 2, mitochondrial SDHAF2 C11orf79 SDH5 PGL2 protein protein human Homo sapiens Human MAVSTVFSTSSLMLALSRHSLLSPLLSVTSFRRFYRGDSPTDSQKDMIEIPLPPWQERTDESIETKRARLLYESRKRGMLENCILLSLFAKEHLQHMTEKQLNLYDRLINEPSNDWDIYYWATEAKPAPEIFENEVMALLRDFAKNKNKEQRLRAPDLEYLFEKPR DIP protein Q9NX18 original sequence version: 106 AB31FD150E1B6ECA ysdh5-ysdh1-1 1 3 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 4 unspecified role unspecified role bait bait TAP-tag TAP-tag tandem tag tandem tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association sdhaf2-sdha-1 2 5 unspecified role unspecified role prey prey human Homo sapiens Human 6 unspecified role unspecified role bait bait Q9NX18:p.Gly78Arg G78R mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain G R This feature has been corrected as a result of our quality control procedures. The original label was 'G78R'. Wed May 02 15:28:29 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'gly78arg' Tue Jun 30 18:12:06 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Gly78Arg' Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range human Homo sapiens Human physical association physical association