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  <entry>
    <source releaseDate="2022-02-03">
      <names>
        <shortLabel>DIP</shortLabel>
        <fullName>Database of Interacting Proteins</fullName>
      </names>
      <xref>
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      </xref>
      <attributeList>
        <attribute name="postaladdress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
        <attribute name="url" nameAc="MI:0614">http://dip.doe-mbi.ucla.edu/</attribute>
        <attribute name="contact-email" nameAc="MI:0634">dip@mbi.ucla.edu</attribute>
      </attributeList>
    </source>
    <experimentList>
      <experimentDescription id="1">
        <names>
          <fullName>A conserved structural motif mediates formation of the periplasmic rings in the type III secretion system.</fullName>
        </names>
        <bibref>
          <xref>
            <primaryRef db="pubmed" dbAc="MI:0446" id="19396170" refType="primary-reference" refTypeAc="MI:0358"/>
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          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">A conserved structural motif mediates formation of the periplasmic rings in the type III secretion system.</attribute>
            <attribute name="journal" nameAc="MI:0885">Nature structural &amp; molecular biology</attribute>
            <attribute name="publication year" nameAc="MI:0886">2009</attribute>
            <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
            <attribute name="author-list" nameAc="MI:0636">Spreter T.,  Yip CK.,  Sanowar S.,  André I.,  Kimbrough TG.,  Vuckovic M.,  Pfuetzner RA.,  Deng W.,  Yu AC.,  Finlay BB.,  Baker D.,  Miller SI.,  Strynadka NC.</attribute>
            <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
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        <xref>
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        </xref>
        <hostOrganismList>
          <hostOrganism ncbiTaxId="90371">
            <names>
              <shortLabel>saltm</shortLabel>
              <fullName>Salmonella typhimurium</fullName>
            </names>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>3d-em</shortLabel>
            <fullName>3D electron microscopy</fullName>
            <alias type="synonym" typeAc="MI:1041">3D-EM</alias>
            <alias type="synonym" typeAc="MI:1041">electron tomog</alias>
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          </xref>
        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>predetermined</shortLabel>
            <fullName>predetermined participant</fullName>
            <alias type="synonym" typeAc="MI:1041">predetermined</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
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          </xref>
        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Spreter T., Yip CK., Sanowar S., André I., Kimbrough TG., Vuckovic M., Pfuetzner RA., Deng W., Yu AC., Finlay BB., Baker D., Miller SI., Strynadka NC.</attribute>
          <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-133023X</attribute>
          <attribute name="journal" nameAc="MI:0885">Nature structural &amp; molecular biology</attribute>
          <attribute name="publication year" nameAc="MI:0886">2009</attribute>
          <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
          <attribute name="title" nameAc="MI:1091">A conserved structural motif mediates formation of the periplasmic rings in the type III secretion system.</attribute>
        </attributeList>
      </experimentDescription>
      <experimentDescription id="2">
        <names>
          <fullName>A conserved structural motif mediates formation of the periplasmic rings in the type III secretion system.</fullName>
        </names>
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          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">A conserved structural motif mediates formation of the periplasmic rings in the type III secretion system.</attribute>
            <attribute name="journal" nameAc="MI:0885">Nature structural &amp; molecular biology</attribute>
            <attribute name="publication year" nameAc="MI:0886">2009</attribute>
            <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
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            <attribute name="imex curation" nameAc="MI:0959"/>
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        </bibref>
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        </xref>
        <hostOrganismList>
          <hostOrganism ncbiTaxId="90371">
            <names>
              <shortLabel>saltm</shortLabel>
              <fullName>Salmonella typhimurium</fullName>
            </names>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>molecular sieving</shortLabel>
            <fullName>molecular sieving</fullName>
            <alias type="go synonym" typeAc="MI:0303">Gel Filtration</alias>
            <alias type="go synonym" typeAc="MI:0303">Size Exclusion Chromatography</alias>
            <alias type="synonym" typeAc="MI:1041">Size Exclusion Chromatography</alias>
            <alias type="synonym" typeAc="MI:1041">Gel Filtration</alias>
            <alias type="synonym" typeAc="MI:1041">Sizing column</alias>
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        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>predetermined</shortLabel>
            <fullName>predetermined participant</fullName>
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        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Spreter T., Yip CK., Sanowar S., André I., Kimbrough TG., Vuckovic M., Pfuetzner RA., Deng W., Yu AC., Finlay BB., Baker D., Miller SI., Strynadka NC.</attribute>
          <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-133022X</attribute>
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          <attribute name="publication year" nameAc="MI:0886">2009</attribute>
          <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
          <attribute name="title" nameAc="MI:1091">A conserved structural motif mediates formation of the periplasmic rings in the type III secretion system.</attribute>
        </attributeList>
      </experimentDescription>
    </experimentList>
    <interactorList>
      <interactor id="3">
        <names>
          <shortLabel>sctc1_salty</shortLabel>
          <fullName>SPI-1 type 3 secretion system secretin</fullName>
          <alias type="gene name" typeAc="MI:0301">sctC1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Protein InvG</alias>
          <alias type="gene name synonym" typeAc="MI:0302">invG</alias>
          <alias type="locus name" typeAc="MI:0305">STM2898</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P35672" version="76" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensemblbacteria" id="AAL21778" version="SP_133" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15771877" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensemblbacteria" id="AAL21778" version="SP_133" refType="transcript"/>
          <secondaryRef db="ensemblbacteria" id="STM2898" version="SP_133" refType="gene"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0009279" version="SP_133"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0009306" version="SP_133"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0015627" version="SP_133"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030254" version="SP_133"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030257" version="SP_133"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" version="SP_133"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003522" version="SP_133"/>
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          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR005644" version="SP_133"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR038591" version="SP_133"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2Y9K" version="SP_133"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3J1V" version="SP_133"/>
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          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6DV3" version="SP_133"/>
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          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7AHI" version="SP_133"/>
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          <secondaryRef db="refseq" dbAc="MI:0481" id="WP_000848113.1"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-48517N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
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            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
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        </interactorType>
        <organism ncbiTaxId="99287">
          <names>
            <shortLabel>salty</shortLabel>
            <fullName>Salmonella typhimurium</fullName>
          </names>
        </organism>
        <sequence>MKTHILLARVLACAALVLVTPGYSSEKIPVTGSGFVAKDDSLRTFFDAMALQLKEPVIVSKMAARKKITGNFEFHDPNALLEKLSLQLGLIWYFDGQAIYIYDASEMRNAVVSLRNVSLNEFNNFLKRSGLYNKNYPLRGDNRKGTFYVSGPPVYVDMVVNAATMMDKQNDGIELGRQKIGVMRLNNTFVGDRTYNLRDQKMVIPGIATAIERLLQGEEQPLGNIVSSEPPAMPAFSANGEKGKAANYAGGMSLQEALKQNAAAGNIKIVAYPDTNSLLVKGTAEQVHFIEMLVKALDVAKRHVELSLWIVDLNKSDLERLGTSWSGSITIGDKLGVSLNQSSISTLDGSRFIAAVNALEEKKQATVVSRPVLLTQENVPAIFDNNRTFYTKLIGERNVALEHVTYGTMIRVLPRFSADGQIEMSLDIEDGNDKTPQSDTTTSVDALPEVGRTLISTIARVPHGKSLLVGGYTRDANTDTVQSIPFLGKLPLIGSLFRYSSKNKSNVVRVFMIEPKEIVDPLTPDASESVNNILKQSGAWSGDDKLQKWVRVYLDRGQEAIK</sequence>
        <attributeList>
          <attribute name="crc64">8022905BE256058D</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
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          <shortLabel>invg-1</shortLabel>
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        <participantList>
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                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
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                  <shortLabel>unspecified role</shortLabel>
                  <fullName>unspecified role</fullName>
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                <names>
                  <shortLabel>saltm</shortLabel>
                  <fullName>Salmonella typhimurium</fullName>
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      </interaction>
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                <fullName>unspecified role</fullName>
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                  <fullName>unspecified role</fullName>
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            <hostOrganismList>
              <hostOrganism ncbiTaxId="90371">
                <names>
                  <shortLabel>saltm</shortLabel>
                  <fullName>Salmonella typhimurium</fullName>
                </names>
              </hostOrganism>
            </hostOrganismList>
          </participant>
        </participantList>
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            <fullName>direct interaction</fullName>
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