DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex. The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex. Nature 2009 imex curation Park BS., Song DH., Kim HM., Choi BS., Lee H., Lee JO. Only protein-protein interactions trini Trichoplusia ni (Cabbage looper) Cabbage looper molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Park BS., Song DH., Kim HM., Choi BS., Lee H., Lee JO. DIP original experiment: DIP-249870X Nature 2009 IMEx The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex. The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex. The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex. Nature 2009 imex curation Park BS., Song DH., Kim HM., Choi BS., Lee H., Lee JO. Only protein-protein interactions trini Trichoplusia ni (Cabbage looper) Cabbage looper x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Park BS., Song DH., Kim HM., Choi BS., Lee H., Lee JO. DIP original experiment: DIP-249871X Nature 2009 IMEx The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex. o00206-1 Toll-like receptor 4 TLR4 hToll protein protein human Homo sapiens Human MMSASRLAGTLIPAMAFLSCVRPESWEPCVEVVPNITYQCMELNFYKIPDNLPFSTKNLDLSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGAYQSLSHLSTLILTGNPIQSLALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAHNLIQSFKLPEYFSNLTNLEHLDLSSNKIQSIYCTDLRVLHQMPLLNLSLDLSLNPMNFIQPGAFKEIRLHKLTLRNNFDSLNVMKTCIQGLAGLEVHRLVLGEFRNEGNLEKFDKSALEGLCNLTIEEFRLAYLDYYLDDIIDLFNCLTNVSSFSLVSVTIERVKDFSYNFGWQHLELVNCKFGQFPTLKLKSLKRLTFTSNKGGNAFSEVDLPSLEFLDLSRNGLSFKGCCSQSDFGTTSLKYLDLSFNGVITMSSNFLGLEQLEHLDFQHSNLKQMSEFSVFLSLRNLIYLDISHTHTRVAFNGIFNGLSSLEVLKMAGNSFQENFLPDIFTELRNLTFLDLSQCQLEQLSPTAFNSLSSLQVLNMSHNNFFSLDTFPYKCLNSLQVLDYSLNHIMTSKKQELQHFPSSLAFLNLTQNDFACTCEHQSFLQWIKDQRQLLVEVERMECATPSDKQGMPVLSLNITCQMNKTIIGVSVLSVLVVSVVAVLVYKFYFHLMLLAGCIKYGRGENIYDAFVIYSSQDEDWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAIAANIIHEGFHKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLSSRAGIIFIVLQKVEKTLLRQQVELYRLLSRNTYLEWEDSVLGRHIFWRRLRKALLDGKSWNPEGTVGTGCNWQEATSI DIP protein O00206-1 original sequence version: 86 DIP protein O00206-1 original sequence version: 91 DIP protein O00206 original sequence version: 135 DIP protein O00206 original sequence version: 138 ly96_human Lymphocyte antigen 96 Protein MD-2 ESOP-1 LY96 ESOP1 MD2 protein protein human Homo sapiens Human MLPFLFFSTLFSSIFTEAQKQYWVCNSSDASISYTYCDKMQYPISINVNPCIELKRSKGLLHIFYIPRRDLKQLYFNLYITVNTMNLPKRKEVICRGSDDDYSFCRALKGETVNTTISFSFKGIKFSKGKYKCVVEAISGSPEEMLFCLEFVILHQPNSN DIP protein Q9Y6Y9 original sequence version: 79 DIP protein Q9Y6Y9 original sequence version: 86 DIP protein Q9Y6Y9 original sequence version: 109 DIP protein Q9Y6Y9 original sequence version: 112 0F92AFF583637C6B ly96-tlr4-8 1 3 unspecified role unspecified role unspecified role unspecified role Region 27-631 Region 27-631 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain trini Trichoplusia ni (Cabbage looper) Cabbage looper 4 unspecified role unspecified role unspecified role unspecified role Region 19-160 Region 19-160 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain trini Trichoplusia ni (Cabbage looper) Cabbage looper direct interaction direct interaction ly96-tlr4-9 2 3 unspecified role unspecified role unspecified role unspecified role Region 27-631 Region 27-631 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain trini Trichoplusia ni (Cabbage looper) Cabbage looper 4 unspecified role unspecified role unspecified role unspecified role Region 19-160 Region 19-160 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain trini Trichoplusia ni (Cabbage looper) Cabbage looper direct interaction direct interaction