DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Nature 2009 imex curation Trompette A., Divanovic S., Visintin A., Blanchard C., Hegde RS., Madan R., Thorne PS., Wills-Karp M., Gioannini TL., Weiss JP., Karp CL. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Trompette A., Divanovic S., Visintin A., Blanchard C., Hegde RS., Madan R., Thorne PS., Wills-Karp M., Gioannini TL., Weiss JP., Karp CL. DIP original experiment: DIP-249759X Nature 2009 IMEx Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Nature 2009 imex curation Trompette A., Divanovic S., Visintin A., Blanchard C., Hegde RS., Madan R., Thorne PS., Wills-Karp M., Gioannini TL., Weiss JP., Karp CL. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Trompette A., Divanovic S., Visintin A., Blanchard C., Hegde RS., Madan R., Thorne PS., Wills-Karp M., Gioannini TL., Weiss JP., Karp CL. DIP original experiment: DIP-249761X Nature 2009 IMEx Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Nature 2009 imex curation Trompette A., Divanovic S., Visintin A., Blanchard C., Hegde RS., Madan R., Thorne PS., Wills-Karp M., Gioannini TL., Weiss JP., Karp CL. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Trompette A., Divanovic S., Visintin A., Blanchard C., Hegde RS., Madan R., Thorne PS., Wills-Karp M., Gioannini TL., Weiss JP., Karp CL. DIP original experiment: DIP-249757X Nature 2009 IMEx Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Nature 2009 imex curation Trompette A., Divanovic S., Visintin A., Blanchard C., Hegde RS., Madan R., Thorne PS., Wills-Karp M., Gioannini TL., Weiss JP., Karp CL. Only protein-protein interactions spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm comigration in sds comigration in sds page comigration in sds anti tag western anti tag western blot anti tag western Trompette A., Divanovic S., Visintin A., Blanchard C., Hegde RS., Madan R., Thorne PS., Wills-Karp M., Gioannini TL., Weiss JP., Karp CL. DIP original experiment: DIP-249763X Nature 2009 IMEx Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Nature 2009 imex curation Trompette A., Divanovic S., Visintin A., Blanchard C., Hegde RS., Madan R., Thorne PS., Wills-Karp M., Gioannini TL., Weiss JP., Karp CL. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip predetermined predetermined participant predetermined Trompette A., Divanovic S., Visintin A., Blanchard C., Hegde RS., Madan R., Thorne PS., Wills-Karp M., Gioannini TL., Weiss JP., Karp CL. DIP original experiment: DIP-249758X Nature 2009 IMEx Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Nature 2009 imex curation Trompette A., Divanovic S., Visintin A., Blanchard C., Hegde RS., Madan R., Thorne PS., Wills-Karp M., Gioannini TL., Weiss JP., Karp CL. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip predetermined predetermined participant predetermined Trompette A., Divanovic S., Visintin A., Blanchard C., Hegde RS., Madan R., Thorne PS., Wills-Karp M., Gioannini TL., Weiss JP., Karp CL. DIP original experiment: DIP-249760X Nature 2009 IMEx Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Nature 2009 imex curation Trompette A., Divanovic S., Visintin A., Blanchard C., Hegde RS., Madan R., Thorne PS., Wills-Karp M., Gioannini TL., Weiss JP., Karp CL. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip predetermined predetermined participant predetermined Trompette A., Divanovic S., Visintin A., Blanchard C., Hegde RS., Madan R., Thorne PS., Wills-Karp M., Gioannini TL., Weiss JP., Karp CL. DIP original experiment: DIP-249764X Nature 2009 IMEx Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Nature 2009 imex curation Trompette A., Divanovic S., Visintin A., Blanchard C., Hegde RS., Madan R., Thorne PS., Wills-Karp M., Gioannini TL., Weiss JP., Karp CL. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip predetermined predetermined participant predetermined Trompette A., Divanovic S., Visintin A., Blanchard C., Hegde RS., Madan R., Thorne PS., Wills-Karp M., Gioannini TL., Weiss JP., Karp CL. DIP original experiment: DIP-249762X Nature 2009 IMEx Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Nature 2009 imex curation Trompette A., Divanovic S., Visintin A., Blanchard C., Hegde RS., Madan R., Thorne PS., Wills-Karp M., Gioannini TL., Weiss JP., Karp CL. Only protein-protein interactions in vitro In vitro pull down pull down predetermined predetermined participant predetermined Trompette A., Divanovic S., Visintin A., Blanchard C., Hegde RS., Madan R., Thorne PS., Wills-Karp M., Gioannini TL., Weiss JP., Karp CL. DIP original experiment: DIP-249765X Nature 2009 IMEx Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. ly96_human Lymphocyte antigen 96 Protein MD-2 ESOP-1 LY96 ESOP1 MD2 protein protein human Homo sapiens Human MLPFLFFSTLFSSIFTEAQKQYWVCNSSDASISYTYCDKMQYPISINVNPCIELKRSKGLLHIFYIPRRDLKQLYFNLYITVNTMNLPKRKEVICRGSDDDYSFCRALKGETVNTTISFSFKGIKFSKGKYKCVVEAISGSPEEMLFCLEFVILHQPNSN DIP protein Q9Y6Y9 original sequence version: 79 DIP protein Q9Y6Y9 original sequence version: 86 DIP protein Q9Y6Y9 original sequence version: 109 DIP protein Q9Y6Y9 original sequence version: 112 0F92AFF583637C6B all2_derpt Mite group 2 allergen Der p 2 DERP2 Allergen Der p II DPX protein protein derpt Dermatophagoides pteronyssinus European house dust mite MMYKILCLSLLVAAVARDQVDVKDCANHEIKKVLVPGCHGSEPCIIHRGKPFQLEAVFEANQNTKTAKIEIKASIDGLEVDVPGIDPNACHYMKCPLVKGQQYDIKYTWNVPKIAPKSENVVVTVKVMGDDGVLACAIATHAKIRD DIP protein P49278 original sequence version: 63 o00206-1 Toll-like receptor 4 TLR4 hToll protein protein human Homo sapiens Human MMSASRLAGTLIPAMAFLSCVRPESWEPCVEVVPNITYQCMELNFYKIPDNLPFSTKNLDLSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGAYQSLSHLSTLILTGNPIQSLALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAHNLIQSFKLPEYFSNLTNLEHLDLSSNKIQSIYCTDLRVLHQMPLLNLSLDLSLNPMNFIQPGAFKEIRLHKLTLRNNFDSLNVMKTCIQGLAGLEVHRLVLGEFRNEGNLEKFDKSALEGLCNLTIEEFRLAYLDYYLDDIIDLFNCLTNVSSFSLVSVTIERVKDFSYNFGWQHLELVNCKFGQFPTLKLKSLKRLTFTSNKGGNAFSEVDLPSLEFLDLSRNGLSFKGCCSQSDFGTTSLKYLDLSFNGVITMSSNFLGLEQLEHLDFQHSNLKQMSEFSVFLSLRNLIYLDISHTHTRVAFNGIFNGLSSLEVLKMAGNSFQENFLPDIFTELRNLTFLDLSQCQLEQLSPTAFNSLSSLQVLNMSHNNFFSLDTFPYKCLNSLQVLDYSLNHIMTSKKQELQHFPSSLAFLNLTQNDFACTCEHQSFLQWIKDQRQLLVEVERMECATPSDKQGMPVLSLNITCQMNKTIIGVSVLSVLVVSVVAVLVYKFYFHLMLLAGCIKYGRGENIYDAFVIYSSQDEDWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAIAANIIHEGFHKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLSSRAGIIFIVLQKVEKTLLRQQVELYRLLSRNTYLEWEDSVLGRHIFWRRLRKALLDGKSWNPEGTVGTGCNWQEATSI DIP protein O00206-1 original sequence version: 86 DIP protein O00206-1 original sequence version: 91 DIP protein O00206 original sequence version: 135 DIP protein O00206 original sequence version: 138 cd14_human Monocyte differentiation antigen CD14 CD14 Myeloid cell-specific leucine-rich glycoprotein protein protein human Homo sapiens Human MERASCLLLLLLPLVHVSATTPEPCELDDEDFRCVCNFSEPQPDWSEAFQCVSAVEVEIHAGGLNLEPFLKRVDADADPRQYADTVKALRVRRLTVGAAQVPAQLLVGALRVLAYSRLKELTLEDLKITGTMPPLPLEATGLALSSLRLRNVSWATGRSWLAELQQWLKPGLKVLSIAQAHSPAFSCEQVRAFPALTSLDLSDNPGLGERGLMAALCPHKFPAIQNLALRNTGMETPTGVCAALAAAGVQPHSLDLSHNSLRATVNPSAPRCMWSSALNSLNLSFAGLEQVPKGLPAKLRVLDLSCNRLNRAPQPDELPEVDNLTLDGNPFLVPGTALPHEGSMNSGVVPACARSTLSVGVSGTLVLLQGARGFA DIP protein P08571 original sequence version: 96 DIP protein P08571 original sequence version: null 1746CDB41F394F8D ly86_human Lymphocyte antigen 86 LY86 MD1 Protein MD-1 protein protein human Homo sapiens Human MKGFTATLFLWTLIFPSCSGGGGGKAWPTHVVCSDSGLEVLYQSCDPLQDFGFSVEKCSKQLKSNINIRFGIILREDIKELFLDLALMSQGSSVLNFSYPICEAALPKFSFCGRRKGEQIYYAGPVNNPEFTIPQGEYQVLLELYTEKRSTVACANATIMCS DIP protein O95711 original sequence version: 88 DIP protein O95711 original sequence version: 81 3E6497E2DB4C6F27 derp2-ly96-1 1 10 unspecified role unspecified role prey prey Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged c-term range C-terminal range c-term range c-term range C-terminal range c-term range human Homo sapiens Human 11 unspecified role unspecified role bait bait HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range human Homo sapiens Human physical association physical association derp2-tlr4-1 3 12 unspecified role unspecified role prey prey YFP-tag YFP-tag yfp tag yellow fluorescent protein tag YFP yellow fluorescent protein yellow fluorescent protein YFP yfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range human Homo sapiens Human 11 unspecified role unspecified role bait bait HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range human Homo sapiens Human physical association physical association derp2-1 4 11 unspecified role unspecified role unspecified role unspecified role His-tag His-tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm covalent binding covalent binding derp2-cd14-1 2 13 unspecified role unspecified role prey prey Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged c-term range C-terminal range c-term range c-term range C-terminal range c-term range human Homo sapiens Human 11 unspecified role unspecified role bait bait HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range human Homo sapiens Human physical association physical association ly86-ly96-1 7 14 unspecified role unspecified role bait bait HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range human Homo sapiens Human 10 unspecified role unspecified role prey prey Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged c-term range C-terminal range c-term range c-term range C-terminal range c-term range human Homo sapiens Human physical association physical association ly96-derp2-1 6 10 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged c-term range C-terminal range c-term range c-term range C-terminal range c-term range human Homo sapiens Human 11 unspecified role unspecified role prey prey HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range human Homo sapiens Human physical association physical association tlr4-derp2-1 5 12 unspecified role unspecified role bait bait YFP-tag YFP-tag yfp tag yellow fluorescent protein tag YFP yellow fluorescent protein yellow fluorescent protein YFP yfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range human Homo sapiens Human 11 unspecified role unspecified role prey prey HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range human Homo sapiens Human physical association physical association ly96-tlr4-7 8 10 unspecified role unspecified role bait bait HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range human Homo sapiens Human 12 unspecified role unspecified role prey prey YFP-tag YFP-tag yfp tag yellow fluorescent protein tag YFP yellow fluorescent protein yellow fluorescent protein YFP yfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range human Homo sapiens Human physical association physical association tlr4-derp2-2 9 12 unspecified role unspecified role bait bait Fc-tag Fc-tag fusion protein fusion protein c-term range C-terminal range c-term range c-term range C-terminal range c-term range Region 24-631 Region 24-631 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human 11 unspecified role unspecified role prey prey derpt Dermatophagoides pteronyssinus European house dust mite direct interaction direct interaction