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  <entry>
    <source releaseDate="2022-02-04">
      <names>
        <shortLabel>DIP</shortLabel>
        <fullName>Database of Interacting Proteins</fullName>
      </names>
      <xref>
        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="identity" refTypeAc="MI:0356"/>
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      </xref>
      <attributeList>
        <attribute name="postaladdress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
        <attribute name="url" nameAc="MI:0614">http://dip.doe-mbi.ucla.edu/</attribute>
        <attribute name="contact-email" nameAc="MI:0634">dip@mbi.ucla.edu</attribute>
      </attributeList>
    </source>
    <experimentList>
      <experimentDescription id="1">
        <names>
          <fullName>Caenorhabditis elegans HCF-1 functions in longevity maintenance as a DAF-16 regulator.</fullName>
        </names>
        <bibref>
          <xref>
            <primaryRef db="pubmed" dbAc="MI:0446" id="18828672" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="doi" dbAc="MI:0574" id="10.1371/journal.pbio.0060233" refType="primary-reference" refTypeAc="MI:0358"/>
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          </xref>
          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">Caenorhabditis elegans HCF-1 functions in longevity maintenance as a DAF-16 regulator.</attribute>
            <attribute name="journal" nameAc="MI:0885">PLoS biology</attribute>
            <attribute name="publication year" nameAc="MI:0886">2008</attribute>
            <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
            <attribute name="author-list" nameAc="MI:0636">Li J.,  Ebata A.,  Dong Y.,  Rizki G.,  Iwata T.,  Lee SS.</attribute>
            <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
          </attributeList>
        </bibref>
        <xref>
          <primaryRef db="imex" dbAc="MI:0670" id="IM-9609" refType="imex-primary" refTypeAc="MI:0662"/>
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        </xref>
        <hostOrganismList>
          <hostOrganism ncbiTaxId="6239">
            <names>
              <shortLabel>caeel</shortLabel>
              <fullName>Caenorhabditis elegans</fullName>
            </names>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>anti bait coip</shortLabel>
            <fullName>anti bait coimmunoprecipitation</fullName>
            <alias type="synonym" typeAc="MI:1041">anti bait coip</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0006" refType="identity" refTypeAc="MI:0356"/>
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          </xref>
        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>predetermined</shortLabel>
            <fullName>predetermined participant</fullName>
            <alias type="synonym" typeAc="MI:1041">predetermined</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
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          </xref>
        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Li J., Ebata A., Dong Y., Rizki G., Iwata T., Lee SS.</attribute>
          <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-113510X</attribute>
          <attribute name="journal" nameAc="MI:0885">PLoS biology</attribute>
          <attribute name="publication year" nameAc="MI:0886">2008</attribute>
          <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
          <attribute name="title" nameAc="MI:1091">Caenorhabditis elegans HCF-1 functions in longevity maintenance as a DAF-16 regulator.</attribute>
        </attributeList>
      </experimentDescription>
      <experimentDescription id="2">
        <names>
          <fullName>Caenorhabditis elegans HCF-1 functions in longevity maintenance as a DAF-16 regulator.</fullName>
        </names>
        <bibref>
          <xref>
            <primaryRef db="pubmed" dbAc="MI:0446" id="18828672" refType="primary-reference" refTypeAc="MI:0358"/>
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            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-16221231" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="imex" dbAc="MI:0670" id="IM-9609" refType="imex-primary" refTypeAc="MI:0662"/>
          </xref>
          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">Caenorhabditis elegans HCF-1 functions in longevity maintenance as a DAF-16 regulator.</attribute>
            <attribute name="journal" nameAc="MI:0885">PLoS biology</attribute>
            <attribute name="publication year" nameAc="MI:0886">2008</attribute>
            <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
            <attribute name="author-list" nameAc="MI:0636">Li J.,  Ebata A.,  Dong Y.,  Rizki G.,  Iwata T.,  Lee SS.</attribute>
            <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
          </attributeList>
        </bibref>
        <xref>
          <primaryRef db="imex" dbAc="MI:0670" id="IM-9609" refType="imex-primary" refTypeAc="MI:0662"/>
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        </xref>
        <hostOrganismList>
          <hostOrganism ncbiTaxId="6239">
            <names>
              <shortLabel>caeel</shortLabel>
              <fullName>Caenorhabditis elegans</fullName>
            </names>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>anti tag coip</shortLabel>
            <fullName>anti tag coimmunoprecipitation</fullName>
            <alias type="synonym" typeAc="MI:1041">anti tag coip</alias>
          </names>
          <xref>
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          </xref>
        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>western blot</shortLabel>
            <fullName>western blot</fullName>
            <alias type="go synonym" typeAc="MI:0303">Immuno blot</alias>
            <alias type="synonym" typeAc="MI:1041">Immuno blot</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
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          </xref>
        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Li J., Ebata A., Dong Y., Rizki G., Iwata T., Lee SS.</attribute>
          <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-113509X</attribute>
          <attribute name="journal" nameAc="MI:0885">PLoS biology</attribute>
          <attribute name="publication year" nameAc="MI:0886">2008</attribute>
          <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
          <attribute name="title" nameAc="MI:1091">Caenorhabditis elegans HCF-1 functions in longevity maintenance as a DAF-16 regulator.</attribute>
        </attributeList>
      </experimentDescription>
    </experimentList>
    <interactorList>
      <interactor id="3">
        <names>
          <shortLabel>hcf1</shortLabel>
          <fullName>Hcf1 related protein 1, confirmed by transcript evidence</fullName>
        </names>
        <xref>
          <primaryRef db="intact" dbAc="MI:0469" id="EBI-16221250" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q18654" version="59" refType="uniprot-removed-ac"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
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            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="6239">
          <names>
            <shortLabel>caeel</shortLabel>
            <fullName>Caenorhabditis elegans</fullName>
          </names>
        </organism>
        <attributeList>
          <attribute name="no-uniprot-update"/>
          <attribute name="caution" nameAc="MI:0618">The sequence has been withdrawn from uniprot.</attribute>
        </attributeList>
      </interactor>
      <interactor id="4">
        <names>
          <shortLabel>foxo_caeel</shortLabel>
          <fullName>Forkhead box protein O</fullName>
          <alias type="gene name synonym" typeAc="MI:0302">Abnormal dauer formation protein 16</alias>
          <alias type="gene name" typeAc="MI:0301">daf-16</alias>
          <alias type="orf name" typeAc="MI:0306">R13H8.1</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="O16850" version="TrEMBL_51" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O16849" version="SP_67" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O18676" version="SP_67" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q86S42" version="SP_67" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1770827" refType="intact-secondary"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="F3NWW7" version="SP_90" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="F3NWX0" version="SP_90" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="G4RQR7" version="SP_90" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="G4S686" version="SP_90" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="G4SKG3" version="SP_90" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="G4SKH0" version="SP_90" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="ensemblmetazoa" id="R13H8.1h.1" version="SP_174" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-324028" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001021593.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001021594.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001021595.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001021597.1"/>
          <secondaryRef db="wormbase" dbAc="MI:0487" id="R13H8.1a"/>
          <secondaryRef db="wormbase" dbAc="MI:0487" id="R13H8.1b"/>
          <secondaryRef db="wormbase" dbAc="MI:0487" id="R13H8.1c"/>
          <secondaryRef db="wormbase" dbAc="MI:0487" id="R13H8.1e"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001021596.1"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-CEL-9607240"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001021598.2"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001251490.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001251492.1"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-CEL-9614399"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-CEL-9615017"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-CEL-9617629"/>
          <secondaryRef db="wormbase" dbAc="MI:0487" id="R13H8.1d"/>
          <secondaryRef db="wormbase" dbAc="MI:0487" id="R13H8.1f"/>
          <secondaryRef db="wormbase" dbAc="MI:0487" id="R13H8.1g"/>
          <secondaryRef db="wormbase" dbAc="MI:0487" id="R13H8.1h"/>
          <secondaryRef db="ensemblmetazoa" id="R13H8.1h.1" version="SP_174" refType="transcript"/>
          <secondaryRef db="ensemblmetazoa" id="WBGene00000912" version="SP_174" refType="gene"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000122" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000977" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000978" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000981" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0002119" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0002821" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003700" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006355" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006357" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006974" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006979" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007568" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007614" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008013" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008286" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008340" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008582" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0009411" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0010286" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0010468" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0010564" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0010628" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0010883" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0017151" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0019899" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0031625" version="SP_174"/>
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          <secondaryRef db="go" dbAc="MI:0448" id="GO:0034599" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0034605" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0040015" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0040024" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042594" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043065" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043565" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043620" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045887" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045944" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0046890" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0050829" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0050830" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0060537" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0061065" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0061066" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071889" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0140297" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1900075" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1900426" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1905909" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1990381" version="SP_174"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001766" version="SP_174"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR030456" version="SP_174"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036388" version="SP_174"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036390" version="SP_174"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045087" version="SP_174"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-CEL-198693"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-CEL-211163"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-CEL-5687128"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-25581N"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-CEL-5689880"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-CEL-1181150"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-CEL-9617828"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-CEL-9634638"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="6239">
          <names>
            <shortLabel>caeel</shortLabel>
            <fullName>Caenorhabditis elegans</fullName>
          </names>
        </organism>
        <sequence>MQLEQKSSLHCSKCRNFLQKFSQDMQAWNCRELDSPLPSDITLHNLEPARPDSGMSFSTDFDDDFFNLDLHQQERSASFGGVTQYSQQFLREKCSFSPYFHTSLETVDSGRTSLYGSNEQCGQLGGASSNGSTAMLHTPDGSNSHQTSFPSDFRMSESPDDTVSGKKTTTRRNAWGNMSYAELITTAIMASPEKRLTLAQVYEWMVQNVPYFRDKGDSNSSAGWKNSIRHNLSLHSRFMRIQNEGAGKSSWWVINPDAKPGRNPRRTRERSNTIETTTKAQLEKSRRGAKKRIKERALMGSLHSTLNGNSIAGSIQTISHDLYDDDSMQGAFDNVPSSFRPRTQSNLSIPGSSSRVSPAIGSDIYDDLEFPSWVGESVPAIPSDIVDRTDQMRIDATTHIGGVQIKQESKPIKTEPIAPPPSYHELNSVRGSCAQNPLLRNPIVPSTNFKPMPLPGAYGNYQNGGITPINWLSTSNSSPLPGIQSCGIVAAQHTVASSSALPIDLENLTLPDQPLMDTMDVDALIRHELSQAGGQHIHFDL</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein O16850 original sequence version: 118</attribute>
          <attribute name="remark-internal">DIP protein O16850 original sequence version: 61</attribute>
          <attribute name="crc64">8A36A86311A32CBB</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="5" imexId="IM-9609-1">
        <names>
          <shortLabel>daf_16-hcf1-1</shortLabel>
        </names>
        <xref>
          <primaryRef db="dip" dbAc="MI:0465" id="DIP-88303E" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-16221252" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-9609-1" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>2</experimentRef>
        </experimentList>
        <participantList>
          <participant id="6">
            <interactorRef>3</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="6239">
                <names>
                  <shortLabel>caeel</shortLabel>
                  <fullName>Caenorhabditis elegans</fullName>
                </names>
              </hostOrganism>
            </hostOrganismList>
          </participant>
          <participant id="7">
            <interactorRef>4</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <featureList>
              <feature id="8">
                <names>
                  <shortLabel>GFP-tag</shortLabel>
                  <fullName>GFP-tag</fullName>
                </names>
                <xref>
                  <primaryRef db="intact" dbAc="MI:0469" id="EBI-16221257" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>gfp tag</shortLabel>
                    <fullName>green fluorescent protein tag</fullName>
                    <alias type="go synonym" typeAc="MI:0303">GFP</alias>
                    <alias type="go synonym" typeAc="MI:0303">green fluorescent protein</alias>
                    <alias type="synonym" typeAc="MI:1041">GFP</alias>
                    <alias type="synonym" typeAc="MI:1041">green fluorescent protein</alias>
                    <alias type="synonym" typeAc="MI:1041">gfp tag</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0367" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608965" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="7491768" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>c-term range</shortLabel>
                        <fullName>C-terminal range</fullName>
                        <alias type="synonym" typeAc="MI:1041">c-term range</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:1039" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-2929799" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14760721" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <endStatus>
                      <names>
                        <shortLabel>c-term range</shortLabel>
                        <fullName>C-terminal range</fullName>
                        <alias type="synonym" typeAc="MI:1041">c-term range</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:1039" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-2929799" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14760721" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                  </featureRange>
                </featureRangeList>
              </feature>
            </featureList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="6239">
                <names>
                  <shortLabel>caeel</shortLabel>
                  <fullName>Caenorhabditis elegans</fullName>
                </names>
              </hostOrganism>
            </hostOrganismList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>physical association</shortLabel>
            <fullName>physical association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
      </interaction>
      <interaction id="9" imexId="IM-9609-2">
        <names>
          <shortLabel>hcf1-daf_16-1</shortLabel>
        </names>
        <xref>
          <primaryRef db="dip" dbAc="MI:0465" id="DIP-88303E" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-16221271" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-9609-2" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="10">
            <interactorRef>3</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="6239">
                <names>
                  <shortLabel>caeel</shortLabel>
                  <fullName>Caenorhabditis elegans</fullName>
                </names>
              </hostOrganism>
            </hostOrganismList>
          </participant>
          <participant id="11">
            <interactorRef>4</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <featureList>
              <feature id="12">
                <names>
                  <shortLabel>GFP-tag</shortLabel>
                  <fullName>GFP-tag</fullName>
                </names>
                <xref>
                  <primaryRef db="intact" dbAc="MI:0469" id="EBI-16221276" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>gfp tag</shortLabel>
                    <fullName>green fluorescent protein tag</fullName>
                    <alias type="go synonym" typeAc="MI:0303">GFP</alias>
                    <alias type="go synonym" typeAc="MI:0303">green fluorescent protein</alias>
                    <alias type="synonym" typeAc="MI:1041">GFP</alias>
                    <alias type="synonym" typeAc="MI:1041">green fluorescent protein</alias>
                    <alias type="synonym" typeAc="MI:1041">gfp tag</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0367" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608965" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="7491768" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>c-term range</shortLabel>
                        <fullName>C-terminal range</fullName>
                        <alias type="synonym" typeAc="MI:1041">c-term range</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:1039" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-2929799" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14760721" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <endStatus>
                      <names>
                        <shortLabel>c-term range</shortLabel>
                        <fullName>C-terminal range</fullName>
                        <alias type="synonym" typeAc="MI:1041">c-term range</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:1039" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-2929799" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14760721" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                  </featureRange>
                </featureRangeList>
              </feature>
            </featureList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="6239">
                <names>
                  <shortLabel>caeel</shortLabel>
                  <fullName>Caenorhabditis elegans</fullName>
                </names>
              </hostOrganism>
            </hostOrganismList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>physical association</shortLabel>
            <fullName>physical association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
      </interaction>
    </interactionList>
  </entry>
</entrySet>