DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Phosphorylation of MCM3 on Ser-112 regulates its incorporation into the MCM2-7 complex. Phosphorylation of MCM3 on Ser-112 regulates its incorporation into the MCM2-7 complex. Proceedings of the National Academy of Sciences of the United States of America 2008 imex curation Lin DI., Aggarwal P., Diehl JA. Only protein-protein interactions mouse Mus musculus Mouse anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Lin DI., Aggarwal P., Diehl JA. DIP original experiment: DIP-111088X Proceedings of the National Academy of Sciences of the United States of America 2008 IMEx Phosphorylation of MCM3 on Ser-112 regulates its incorporation into the MCM2-7 complex. Phosphorylation of MCM3 on Ser-112 regulates its incorporation into the MCM2-7 complex. Phosphorylation of MCM3 on Ser-112 regulates its incorporation into the MCM2-7 complex. Proceedings of the National Academy of Sciences of the United States of America 2008 imex curation Lin DI., Aggarwal P., Diehl JA. Only protein-protein interactions mouse Mus musculus Mouse anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Lin DI., Aggarwal P., Diehl JA. DIP original experiment: DIP-111089X Proceedings of the National Academy of Sciences of the United States of America 2008 IMEx Phosphorylation of MCM3 on Ser-112 regulates its incorporation into the MCM2-7 complex. Phosphorylation of MCM3 on Ser-112 regulates its incorporation into the MCM2-7 complex. Phosphorylation of MCM3 on Ser-112 regulates its incorporation into the MCM2-7 complex. Proceedings of the National Academy of Sciences of the United States of America 2008 imex curation Lin DI., Aggarwal P., Diehl JA. Only protein-protein interactions mouse Mus musculus Mouse anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Lin DI., Aggarwal P., Diehl JA. DIP original experiment: DIP-111090X Proceedings of the National Academy of Sciences of the United States of America 2008 IMEx Phosphorylation of MCM3 on Ser-112 regulates its incorporation into the MCM2-7 complex. mcm7_mouse DNA replication licensing factor MCM7 CDC47 homolog Mcm7 Cdc47 Mcmd7 protein protein mouse Mus musculus Mouse MALKDYAIEKEKVKKFLQEFYYENELGKKQFKYGTQLVHLAHREQVALYVDLDDIAEDDPELVDSICENAKRYSRLFGDVVQELLPEYKEKEVVNKDVLDVYIEHRLMMEQRSRDPGAVRNPQNQYPSELMRRFELYFRGPSSSKPRVIREVRADSVGKLLTVRGIVTRVSEVKPRMVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSKFVKFQEMKIQEHSDQVPVGNIPRSITVVLEGENTRIAQPGDHVSVTGIFLPVLRTGFQQMAQGLLSETYLEAHWIVKMTKSDDDVSGAGELSSEELKQIAEEDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQSPQGMKIRGNIHICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNVQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPAQFEPLDMKLMRRYIAMCHERQPTVPESLADYITAAYVEMRREARASKDATYTSARTLLAILRLSTALARLRMVDIVEKEDVNEAIRLMEMSKDSLLGEKGQTARTQRPADVIFATIRELVSRGRSVHFSEAEQRCISRGFTPAQFQAALDEYEELNVWQVNTSRTRITFV DIP protein Q61881 original sequence version: 65 019AE8E04BB8EB3C mcm3_mouse DNA replication licensing factor MCM3 Mcm3 Mcmd Mcmd3 DNA polymerase alpha holoenzyme-associated protein P1 P1-MCM3 protein protein mouse Mus musculus Mouse MAGTVVLDDVELREAQRDYLDFLDDEEDQGIYQNKVRELISDNQYRLIVSVNDLRRKNEKRANRLLNNAFEELVAFQRALKDFVASIDATYAKQYEEFYIGLEGSFGSKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEENNPLETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKVKPGDRIQVVGTYRCLPGKKGCYTSGTFRTVLIACNVKQMSKDIQPAFSADDIAKIKKFSKTRSKDVFEQLARSLAPSIHGHDYVKKAILCLLLGGVERELENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHQYRAPGEQDGDALPLGSSVDILATDDPDFTQDDQQDTRIYEKHDSLLHGTKKKKEKMVSAAFMKKYIHVAKIIKPTLTQESAAYIAEEYSRLRSQDSMSSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKASEDESDLEDEEEKSQEDTEQKRKRRKTHAKDGESYDPYDFSEAETQMPQVHTPKTDDSQEKTDDSQETQDSQKVELSEPRLKAFKAALLEVFQEAHEQSVGMLHLTESINRNREEPFSSEEIQACLSRMQDDNQVMVSEGIVFLI DIP protein P25206 original sequence version: 76 3C8653CF13D0F140 mcm5_mouse DNA replication licensing factor MCM5 Mcm5 Cdc46 Mcmd5 CDC46 homolog P1-CDC46 protein protein mouse Mus musculus Mouse MSGFDDPGIFYSDSFGGDPGAEEGQARKSQLQRRFKEFLRQYRVGTDRTGFTFKYRDELKRHYNLGEYWIEVEMEDLASFDEELADHLHKQPAEHLQLLEEAAKEVADEVTRPRPAGDELLQDIQVMLKSDASPSSIRILKSDMMSHLVKIPGIIISASAVRAKATRISIQCRSCHNTLTNIAMRPGLEGYALPRKCNMDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCDRYLCDKVVPGNRVTIMGIYSIKKFGLNPSKGRDRVGVGIRSSYIRVLGIQVDTDGSGRSFAGSVSPQEEEEFRRLAALPNIYELISKSISPSIFGGMDMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVIRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDETKGEDNIDFMPTILSRFDMIFIVKDEHNEERDMMLAKHVMTLHVSALTQTQAVEGEIDLAKMKKFIAYCRARCGPRLSAEAAEKLKNRYIIMRSGARQHERDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVSTLDAALSGNLSGVEGFTTQEDQEMLSRIEKQLKRRFAIGSQVSEHSIVQDFTKQKYPEHAIRKVLQLMLRRGEIQHRMQRKVLYRLK DIP protein P49718 original sequence version: 51 06B4DCABCECDD5D2 mcm2_mouse DNA replication licensing factor MCM2 Minichromosome maintenance protein 2 homolog Nuclear protein BM28 Mcm2 Bm28 Cdcl1 Kiaa0030 Mcmd2 protein protein mouse Mus musculus Mouse MAESSESLSASSPARQRRRISDPLTSSPGRSSRRADALTSSPGRDLPPFEDESEGLLGTEGPMEEEEDGEELIGDGMERDYRPIPELDVYEAEGLALDDEDVEELTASQREAAERTMRQRDREAGRGLGRMRRGLLYDSSEEDEERPARKRRHVERATEDGEEDEEMIESIENLEDLKGHSVREWVSMAGPRLEIHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQIFDEAALEVVLAMYPKYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCSKCNFVLGPFCQSQNQEVKPGSCPECQSAGPFEINMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNTANGFPVFATIILANHVAKKDNKVAVGELTDEDVKMITGLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDVLCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKKDEGLTNGGTLEPAMPNTYGVEPLPQEVLKKYIIYAKERVRPKLNQMDQDKVARMYSDLRKESMATGSIPITVRHIESMIRMAEAHARMHLRDYVMEDDVNMAIRVMMESFIDTQKFSVMRSMRKTFARYLSFRRDNNDLLLFILKQLVAEQVTYQRNRFGAQQDTIEIPEKDLMDKARQINIHNLSAFYDSDLFKFNKFSRDLKRKLILQQF DIP protein P97310 original sequence version: 77 7B61C13DAD1CAC58 mcm3-mcm5-7 3 6 unspecified role unspecified role prey prey mouse Mus musculus Mouse 5 unspecified role unspecified role bait bait P25206:p.Ser112Ala S112A mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain S A This feature has been corrected as a result of our quality control procedures. The original label was 'S112A'. Wed May 02 20:00:15 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ser112ala' Tue Jun 30 16:39:41 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ser112Ala' Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range P25206:p.[Ser112Ala;Thr719Ala] S112A/T719A mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain T A certain certain sequence position certain certain certain sequence position certain S A This feature has been corrected as a result of our quality control procedures. The original label was 'S112A/T719A'. Wed May 02 18:46:22 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ser112ala,thr719ala' Tue Jun 30 18:06:59 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Ser112Ala;Thr719Ala]' P25206:p.[Ser112Ala;Ser611Ala] S112A/S611A mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain S A certain certain sequence position certain certain certain sequence position certain S A This feature has been corrected as a result of our quality control procedures. The original label was 'S112A/S611A'. Wed May 02 18:35:13 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ser112ala,ser611ala' Tue Jun 30 16:47:14 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Ser112Ala;Ser611Ala]' P25206:p.[Ser112Ala;Thr464Ala;Ser611Ala;Thr719Ala] S112A/S611A/T464A/T719A mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain T A certain certain sequence position certain certain certain sequence position certain S A certain certain sequence position certain certain certain sequence position certain T A certain certain sequence position certain certain certain sequence position certain S A This feature has been corrected as a result of our quality control procedures. The original label was 'S112A/S611A/T464A/T719A'. Wed May 02 19:30:46 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ser112ala,thr464ala,ser611ala,thr719ala' Tue Jun 30 18:26:20 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Ser112Ala;Thr464Ala;Ser611Ala;Thr719Ala]' mouse Mus musculus Mouse physical association physical association mcm3-mcm2-8 1 7 unspecified role unspecified role prey prey mouse Mus musculus Mouse 5 unspecified role unspecified role bait bait P25206:p.Ser112Ala S112A mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain S A This feature has been corrected as a result of our quality control procedures. The original label was 'S112A'. Wed May 02 20:13:48 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ser112ala' Tue Jun 30 16:03:41 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ser112Ala' Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range mouse Mus musculus Mouse physical association physical association mcm3-mcm7-2 2 4 unspecified role unspecified role prey prey mouse Mus musculus Mouse 5 unspecified role unspecified role bait bait P25206:p.Ser112Ala S112A mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain S A This feature has been corrected as a result of our quality control procedures. The original label was 'S112A'. Wed May 02 17:41:33 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ser112ala' Tue Jun 30 18:11:48 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ser112Ala' Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range mouse Mus musculus Mouse physical association physical association