DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu A nuclear receptor-like pathway regulating multidrug resistance in fungi. A nuclear receptor-like pathway regulating multidrug resistance in fungi. Nature 2008 imex curation Thakur JK., Arthanari H., Yang F., Pan SJ., Fan X., Breger J., Frueh DP., Gulshan K., Li DK., Mylonakis E., Struhl K., Moye-Rowley WS., Cormack BP., Wagner G., Näär AM. Only protein-protein interactions in vitro In vitro pull down pull down predetermined predetermined participant predetermined Thakur JK., Arthanari H., Yang F., Pan SJ., Fan X., Breger J., Frueh DP., Gulshan K., Li DK., Mylonakis E., Struhl K., Moye-Rowley WS., Cormack BP., Wagner G., Näär AM. DIP original experiment: DIP-250261X Nature 2008 IMEx A nuclear receptor-like pathway regulating multidrug resistance in fungi. A nuclear receptor-like pathway regulating multidrug resistance in fungi. A nuclear receptor-like pathway regulating multidrug resistance in fungi. Nature 2008 imex curation Thakur JK., Arthanari H., Yang F., Pan SJ., Fan X., Breger J., Frueh DP., Gulshan K., Li DK., Mylonakis E., Struhl K., Moye-Rowley WS., Cormack BP., Wagner G., Näär AM. Only protein-protein interactions in vitro In vitro pull down pull down predetermined predetermined participant predetermined Thakur JK., Arthanari H., Yang F., Pan SJ., Fan X., Breger J., Frueh DP., Gulshan K., Li DK., Mylonakis E., Struhl K., Moye-Rowley WS., Cormack BP., Wagner G., Näär AM. DIP original experiment: DIP-250259X Nature 2008 IMEx A nuclear receptor-like pathway regulating multidrug resistance in fungi. A nuclear receptor-like pathway regulating multidrug resistance in fungi. A nuclear receptor-like pathway regulating multidrug resistance in fungi. Nature 2008 imex curation Thakur JK., Arthanari H., Yang F., Pan SJ., Fan X., Breger J., Frueh DP., Gulshan K., Li DK., Mylonakis E., Struhl K., Moye-Rowley WS., Cormack BP., Wagner G., Näär AM. Only protein-protein interactions in vitro In vitro pull down pull down predetermined predetermined participant predetermined Thakur JK., Arthanari H., Yang F., Pan SJ., Fan X., Breger J., Frueh DP., Gulshan K., Li DK., Mylonakis E., Struhl K., Moye-Rowley WS., Cormack BP., Wagner G., Näär AM. DIP original experiment: DIP-250264X Nature 2008 IMEx A nuclear receptor-like pathway regulating multidrug resistance in fungi. A nuclear receptor-like pathway regulating multidrug resistance in fungi. A nuclear receptor-like pathway regulating multidrug resistance in fungi. Nature 2008 imex curation Thakur JK., Arthanari H., Yang F., Pan SJ., Fan X., Breger J., Frueh DP., Gulshan K., Li DK., Mylonakis E., Struhl K., Moye-Rowley WS., Cormack BP., Wagner G., Näär AM. Only protein-protein interactions yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Thakur JK., Arthanari H., Yang F., Pan SJ., Fan X., Breger J., Frueh DP., Gulshan K., Li DK., Mylonakis E., Struhl K., Moye-Rowley WS., Cormack BP., Wagner G., Näär AM. DIP original experiment: DIP-250255X Nature 2008 IMEx A nuclear receptor-like pathway regulating multidrug resistance in fungi. A nuclear receptor-like pathway regulating multidrug resistance in fungi. A nuclear receptor-like pathway regulating multidrug resistance in fungi. Nature 2008 imex curation Thakur JK., Arthanari H., Yang F., Pan SJ., Fan X., Breger J., Frueh DP., Gulshan K., Li DK., Mylonakis E., Struhl K., Moye-Rowley WS., Cormack BP., Wagner G., Näär AM. Only protein-protein interactions in vitro In vitro pull down pull down predetermined predetermined participant predetermined Thakur JK., Arthanari H., Yang F., Pan SJ., Fan X., Breger J., Frueh DP., Gulshan K., Li DK., Mylonakis E., Struhl K., Moye-Rowley WS., Cormack BP., Wagner G., Näär AM. DIP original experiment: DIP-250263X Nature 2008 IMEx A nuclear receptor-like pathway regulating multidrug resistance in fungi. A nuclear receptor-like pathway regulating multidrug resistance in fungi. A nuclear receptor-like pathway regulating multidrug resistance in fungi. Nature 2008 imex curation Thakur JK., Arthanari H., Yang F., Pan SJ., Fan X., Breger J., Frueh DP., Gulshan K., Li DK., Mylonakis E., Struhl K., Moye-Rowley WS., Cormack BP., Wagner G., Näär AM. Only protein-protein interactions in vitro In vitro pull down pull down predetermined predetermined participant predetermined Thakur JK., Arthanari H., Yang F., Pan SJ., Fan X., Breger J., Frueh DP., Gulshan K., Li DK., Mylonakis E., Struhl K., Moye-Rowley WS., Cormack BP., Wagner G., Näär AM. DIP original experiment: DIP-250265X Nature 2008 IMEx A nuclear receptor-like pathway regulating multidrug resistance in fungi. A nuclear receptor-like pathway regulating multidrug resistance in fungi. A nuclear receptor-like pathway regulating multidrug resistance in fungi. Nature 2008 imex curation Thakur JK., Arthanari H., Yang F., Pan SJ., Fan X., Breger J., Frueh DP., Gulshan K., Li DK., Mylonakis E., Struhl K., Moye-Rowley WS., Cormack BP., Wagner G., Näär AM. Only protein-protein interactions in vitro In vitro pull down pull down predetermined predetermined participant predetermined Thakur JK., Arthanari H., Yang F., Pan SJ., Fan X., Breger J., Frueh DP., Gulshan K., Li DK., Mylonakis E., Struhl K., Moye-Rowley WS., Cormack BP., Wagner G., Näär AM. DIP original experiment: DIP-250256X Nature 2008 IMEx A nuclear receptor-like pathway regulating multidrug resistance in fungi. A nuclear receptor-like pathway regulating multidrug resistance in fungi. A nuclear receptor-like pathway regulating multidrug resistance in fungi. Nature 2008 imex curation Thakur JK., Arthanari H., Yang F., Pan SJ., Fan X., Breger J., Frueh DP., Gulshan K., Li DK., Mylonakis E., Struhl K., Moye-Rowley WS., Cormack BP., Wagner G., Näär AM. Only protein-protein interactions in vitro In vitro pull down pull down predetermined predetermined participant predetermined Thakur JK., Arthanari H., Yang F., Pan SJ., Fan X., Breger J., Frueh DP., Gulshan K., Li DK., Mylonakis E., Struhl K., Moye-Rowley WS., Cormack BP., Wagner G., Näär AM. DIP original experiment: DIP-250266X Nature 2008 IMEx A nuclear receptor-like pathway regulating multidrug resistance in fungi. A nuclear receptor-like pathway regulating multidrug resistance in fungi. A nuclear receptor-like pathway regulating multidrug resistance in fungi. Nature 2008 imex curation Thakur JK., Arthanari H., Yang F., Pan SJ., Fan X., Breger J., Frueh DP., Gulshan K., Li DK., Mylonakis E., Struhl K., Moye-Rowley WS., Cormack BP., Wagner G., Näär AM. Only protein-protein interactions in vitro In vitro nmr nuclear magnetic resonance NMR NMR nmr predetermined predetermined participant predetermined Thakur JK., Arthanari H., Yang F., Pan SJ., Fan X., Breger J., Frueh DP., Gulshan K., Li DK., Mylonakis E., Struhl K., Moye-Rowley WS., Cormack BP., Wagner G., Näär AM. DIP original experiment: DIP-250258X Nature 2008 IMEx A nuclear receptor-like pathway regulating multidrug resistance in fungi. A nuclear receptor-like pathway regulating multidrug resistance in fungi. A nuclear receptor-like pathway regulating multidrug resistance in fungi. Nature 2008 imex curation Thakur JK., Arthanari H., Yang F., Pan SJ., Fan X., Breger J., Frueh DP., Gulshan K., Li DK., Mylonakis E., Struhl K., Moye-Rowley WS., Cormack BP., Wagner G., Näär AM. Only protein-protein interactions in vitro In vitro pull down pull down weight silver stain molecular weight estimation by silver staining weight silver stain Thakur JK., Arthanari H., Yang F., Pan SJ., Fan X., Breger J., Frueh DP., Gulshan K., Li DK., Mylonakis E., Struhl K., Moye-Rowley WS., Cormack BP., Wagner G., Näär AM. DIP original experiment: DIP-250260X Nature 2008 IMEx A nuclear receptor-like pathway regulating multidrug resistance in fungi. A nuclear receptor-like pathway regulating multidrug resistance in fungi. A nuclear receptor-like pathway regulating multidrug resistance in fungi. Nature 2008 imex curation Thakur JK., Arthanari H., Yang F., Pan SJ., Fan X., Breger J., Frueh DP., Gulshan K., Li DK., Mylonakis E., Struhl K., Moye-Rowley WS., Cormack BP., Wagner G., Näär AM. Only protein-protein interactions in vitro In vitro nmr nuclear magnetic resonance NMR NMR nmr predetermined predetermined participant predetermined Thakur JK., Arthanari H., Yang F., Pan SJ., Fan X., Breger J., Frueh DP., Gulshan K., Li DK., Mylonakis E., Struhl K., Moye-Rowley WS., Cormack BP., Wagner G., Näär AM. DIP original experiment: DIP-250257X Nature 2008 IMEx A nuclear receptor-like pathway regulating multidrug resistance in fungi. A nuclear receptor-like pathway regulating multidrug resistance in fungi. A nuclear receptor-like pathway regulating multidrug resistance in fungi. Nature 2008 imex curation Thakur JK., Arthanari H., Yang F., Pan SJ., Fan X., Breger J., Frueh DP., Gulshan K., Li DK., Mylonakis E., Struhl K., Moye-Rowley WS., Cormack BP., Wagner G., Näär AM. Only protein-protein interactions in vitro In vitro pull down pull down predetermined predetermined participant predetermined Thakur JK., Arthanari H., Yang F., Pan SJ., Fan X., Breger J., Frueh DP., Gulshan K., Li DK., Mylonakis E., Struhl K., Moye-Rowley WS., Cormack BP., Wagner G., Näär AM. DIP original experiment: DIP-250262X Nature 2008 IMEx A nuclear receptor-like pathway regulating multidrug resistance in fungi. med15_human Mediator of RNA polymerase II transcription subunit 15 MED15 ARC105 CTG7A Mediator complex subunit 15 Positive cofactor 2 glutamine/Q-rich-associated protein TPA-inducible gene 1 protein Activator-recruited cofactor 105 kDa component CTG repeat protein 7a Trinucleotide repeat-containing gene 7 protein TIG1 PCQAP TNRC7 protein protein human Homo sapiens Human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protein Q96RN5 original sequence version: 124 DIP protein Q96RN5 original sequence version: 114 DIP protein Q96RN5 original sequence version: 86 BB6AC6C63ED2F97E creb1_human Cyclic AMP-responsive element-binding protein 1 CREB1 protein protein human Homo sapiens Human MTMESGAENQQSGDAAVTEAENQQMTVQAQPQIATLAQVSMPAAHATSSAPTVTLVQLPNGQTVQVHGVIQAAQPSVIQSPQVQTVQISTIAESEDSQESVDSVTDSQKRREILSRRPSYRKILNDLSSDAPGVPRIEEEKSEEETSAPAITTVTVPTPIYQTSSGQYIAITQGGAIQLANNGTDGVQGLQTLTMTNAAATQPGTTILQYAQTTDGQQILVPSNQVVVQAASGDVQTYQIRTAPTSTIAPGVVMASSPALPTQPAEEAARKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKSD DIP protein P16220 original sequence version: 169 DIP protein P16220 original sequence version: 158 F5BA8200EE5184B7 cbp_mouse Histone lysine acetyltransferase CREBBP Crebbp Cbp Protein-lysine acetyltransferase CREBBP protein protein mouse Mus musculus Mouse MAENLLDGPPNPKRAKLSSPGFSANDNTDFGSLFDLENDLPDELIPNGELSLLNSGNLVPDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSTNMASLGAMGKSPLNQGDSSTPNLPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPATSQTGPGICMNANFNQTHPGLLNSNSGHSLMNQAQQGQAQVMNGSLGAAGRGRGAGMPYPAPAMQGATSSVLAETLTQVSPQMAGHAGLNTAQAGGMTKMGMTGTTSPFGQPFSQTGGQQMGATGVNPQLASKQSMVNSLPAFPTDIKNTSVTTVPNMSQLQTSVGIVPTQAIATGPTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGAGQQNATSLSNPNPIDPSSMQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPPAHQQMRTLNALGNNPMSIPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGSLSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPASGAQPPVIPPAQSVRPPNGPLPLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMASVPGMAISPSRMPQPPNMMGTHANNIMAQAPTQNQFLPQNQFPSSSGAMSVNSVGMGQPAAQAGVSQGQVPGAALPNPLNMLAPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHPTAPGMTPPQPAAPTQPSTPVSSGQTPTPTPGSVPSAAQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHTQPPGTPLSQAAASIDNRVPTPSSVTSAETSSQQPGPDVPMLEMKTEVQTDDAEPEPTESKGEPRSEMMEEDLQGSSQVKEETDTTEQKSEPMEVEEKKPEVKVEAKEEEENSSNDTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQNTALIAPHQIQGRVYISYLDSIHFFRPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERIINDYKDIFKQANEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKKEESTAASETPEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQKLYATMEKHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHTHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVNMSPAGFPNVARTQPPTIVSAGKPTNQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRANINNGMPPGRAGMGTPGSQMTPVGLNVPRPNQVSGPVMSSMPPGQWQQAPIPQQQPMPGMPRPVMSMQAQAAVAGPRMPNVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPPQPAMGGLNPQGQALNIMNPGHNPNMTNMNPQYREMVRRQLLQHQQQQQQQQQQQQQQQNSASLAGGMAGHSQFQQPQGPGGYAPAMQQQRMQQHLPIQGSSMGQMAAPMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSMDQGHLGNPEQSAMLPQLNTPNRSALSSELSLVGDTTGDTLEKFVEGL DIP protein P45481 original sequence version: 148 DIP protein P45481 original sequence version: 126 DIP protein P45481 original sequence version: 152 DIP protein P45481 original sequence version: 115 DIP protein P45481 original sequence version: 127 DIP protein P45481 original sequence version: 123 DIP protein P45481 original sequence version: 149 DIP protein P45481 original sequence version: 156 DIP protein P45481 original sequence version: 169 DIP protein P45481 original sequence version: 175 DIP protein P45481 original sequence version: 135 D89AF52B7BD33347 med15_yeast Mediator of RNA polymerase II transcription subunit 15 YOL051W GAL11 RAR3 SPT13 ABE1 MED15 SDS4 Mediator complex subunit 15 Transcription regulatory protein GAL11 Basal expression activator protein 1 Autonomous replication regulatory protein 3 Defective silencing suppressor protein 4 Ty insertion suppressor protein 13 protein protein yeast Saccharomyces cerevisiae Baker's yeast MSAAPVQDKDTLSNAERAKNVNGLLQVLMDINTLNGGSSDTADKIRIHAKNFEAALFAKSSSKKEYMDSMNEKVAVMRNTYNTRKNAVTAAAANNNIKPVEQHHINNLKNSGNSANNMNVNMNLNPQMFLNQQAQARQQVAQQLRNQQQQQQQQQQQQRRQLTPQQQQLVNQMKVAPIPKQLLQRIPNIPPNINTWQQVTALAQQKLLTPQDMEAAKEVYKIHQQLLFKARLQQQQAQAQAQANNNNNGLPQNGNINNNINIPQQQQMQPPNSSANNNPLQQQSSQNTVPNVLNQINQIFSPEEQRSLLQEAIETCKNFEKTQLGSTMTEPVKQSFIRKYINQKALRKIQALRDVKNNNNANNNGSNLQRAQNVPMNIIQQQQQQNTNNNDTIATSATPNAAAFSQQQNASSKLYQMQQQQQAQAQAQAQAQAQAQAQAQAQAAQAAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAHAQHQPSQQPQQAQQQPNPLHGLTPTAKDVEVIKQLSLDASKTNLRLTDVTNSLSNEEKEKIKMKLKQGQKLFVQVSNFAPQVYIITKNENFLKEVFQLRIFVKEILEKCAEGIFVVKLDTVDRLIIKYQKYWESMRIQILRRQAILRQQQQMANNNGNPGTTSTGNNNNIATQQNMQQSLQQMQHLQQLKMQQQQQQQQQQQQQQQQQQQQQQQHIYPSSTPGVANYSAMANAPGNNIPYMNHKNTSSMDFLNSMENTPKVPVSAAATPSLNKTINGKVNGRTKSNTIPVTSIPSTNKKLSISNAASQQPTPRSASNTAKSTPNTNPSPLKTQTKNGTPNPNNMKTVQSPMGAQPSYNSAIIENAFRKEELLLKDLEIRKLEISSRFKHRQEIFKDSPMDLFMSTLGDCLGIKDEEMLTSCTIPKAVVDHINGSGKRKPTKAAQRARDQDSIDISIKDNKLVMKSKFNKSNRSYSIALSNVAAIFKGIGGNFKDLSTLVHSSSPSTSSNMDVGNPRKRKASVLEISPQDSIASVLSPDSNIMSDSKKIKVDSPDDPFMTKSGATTSEKQEVTNEAPFLTSGTSSEQFNVWDWNNWTSAT 275C78721B5415C7 275C78721B5415C7 q66wf3_cangb PDR1 AO440_000017 protein protein cangb Candida glabrata Yeast Torulopsis glabrata MQTLETTSKSNPGEVKAQKPSTRRTKVGKACDSCRRRKIKCNGLKPCPSCTIYGCECTYTDAKSTKNLKSNDAGKPKPTGRVSKNKETTRIDKDIRKSEQQYVPINANIHVGPRFPSENILNGYPQCGAPQNNVVGNPLAVNPQCHRGLSETPMSSTFKESNLRDDRLLQSSDTDDMRNGDSEERDLKGSDSENVKSKDNKSDPLIIYKDDTHIESTVNKLTQAVNELKSLQNAPSSIKSSIDAIELQLRNILDNWKPEVDFEKAKINESATTKSLETNLLRNKYTNHVHLTRFRIWIDYKNANKNNHFMGECGFSLAESFFASNQPLVDELFGLYSQVEAFSLQGLGYCVHLYEPYMKTEEAIKLMKETLYIILRFIDICVHHINEESISIANPLETYLRKKHLMPMTPTPRSSYGSPQSASTKSLVSKIIERIPQPFIESVTNVSSLQLLDLRDDESKMFGTLLNMCKSIRRKFDSVMSDYDSIVTEKSEGEQNDGKVTVAEFTSLCEAEEMLLALCYNYYNLTLYSFFEFGTNIEYMEHLLLLLEEQLALDEYYGFEKVLNVAVANAKKMGFHRWEFYVGYEESTAEKRRLLWWKLYNYEKASTMKKGFFSVIDDATVNCLLPKIFRNFGYLDRVEFLENIQKPMDLSVFSDVPISVLCKYGELALTIVTSEFHEKFLYADRYTSIRNSAKPPTLKNQLIKEIVDGIAYTETSYEAIRKQTAKLWDIALGKVTKDKINKEDTAAASKFTLSYEYHRFRLINMADNLIARLMVKPKSDWLISVMKGHLNRLYEHWKVMNEIILSMDNDYSIATTFEYYAPSCLCLATQTFLIVRNMEMDDVKMMVAVYKRFLNLGMFLQSAKVCSLADSHTFRDFSRSFSFITIISRLMIIEFMQIKELTKVEFIEKFSEVCPDLADLPPMLLDPNSCLYFSLLQQIKKSGFTLSFKKILEDARMMDFNYDRNLDSEAIKKCNGEFSKSMPSCTNVSDTTTAVSDNSAKKKASMGSARVNSTDTLTASPLSGLRNQTQLDSKDSVPSLEAYTPIDSVSDVPTGEINVPFPPVYNQNGLDQQTTYNLGTLDEFVNKGDLNELYNSLWGDLFSDVYL DIP protein Q66WF3 original sequence version: 41 myb_human Transcriptional activator Myb MYB Proto-oncogene c-Myb protein protein human Homo sapiens Human MARRPRHSIYSSDEDDEDFEMCDHDYDGLLPKSGKRHLGKTRWTREEDEKLKKLVEQNGTDDWKVIANYLPNRTDVQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHLNPEVKKTSWTEEEDRIIYQAHKRLGNRWAEIAKLLPGRTDNAIKNHWNSTMRRKVEQEGYLQESSKASQPAVATSFQKNSHLMGFAQAPPTAQLPATGQPTVNNDYSYYHISEAQNVSSHVPYPVALHVNIVNVPQPAAAAIQRHYNDEDPEKEKRIKELELLLMSTENELKGQQVLPTQNHTCSYPGWHSTTIADHTRPHGDSAPVSCLGEHHSTPSLPADPGSLPEESASPARCMIVHQGTILDNVKNLLEFAETLQFIDSFLNTSSNHENSDLEMPSLTSTPLIGHKLTVTTPFHRDQTVKTQKENTVFRTPAIKRSILESSPRTPTPFKHALAAQEIKYGPLKMLPQTPSHLVEDLQDVIKQESDESGIVAEFQENGPPLLKKIKQEVESPTDKSGNFFCSHHWEGDSLNTQLFTQTSPVADAPNILTSSVLMAPASEDEDNVLKAFTVPKNRSLASPLQPCSSTWEPASCGKMEEQMTSSSQARKYVNAFSARTLVM DIP protein P10242 original sequence version: 144 DIP protein P10242 original sequence version: 133 DIP protein P10242 original sequence version: 157 FD5E6694020426ED pdr1_yeast Transcription factor PDR1 PDR1 ANT1 BOR2 CYH3 NRA2 SMR2 AMY1 TIL1 TPE1 TPE3 Pleiotropic drug resistance protein 1 YGL013C protein protein yeast Saccharomyces cerevisiae Baker's yeast MRGLTPKNGVHIETGPDTESSADSSNFSTGFSGKIRKPRSKVSKACDNCRKRKIKCNGKFPCASCEIYSCECTFSTRQGGARIKNLHKTSLEGTTVQVKEETDSSSTSFSNPQRCTDGPCAVEQPTKFFENFKLGGRSSGDNSGSDGKNDDDVNRNGFYEDDSESQATLTSLQTTLKNLKEMAHLGTHVTSAIESIELQISDLLKRWEPKVRTKELATTKFYPNKSIETQLMKNKYCDVVHLTRYAAWSNNKKDQDTSSQPLIDEIFGLYSPFQFLSLQGIGKCFQNYRSKSKCEIFPRTAKETIYIMLRFFDVCFHHINQGCVSIANPLENYLQKMNLLPSTPSSISSAGSPNTAHTKSHVALVINHLPQPFVRNITGISNSELLSEMNNDISMFGILLKMLDMHKNSYQNFLMEITSNPSVAKNTQSIDVLQEFIHYCQAGEALIALCYSYYNSTLYNYVDFTCDITHLEQLLYFLDLLFWLSEIYGFEKVLNVAVHFVSRVGLSRWEFYVGLDENFAERRRNLWWKAFYFEKTLASKLGYPSNIDDSKINCLLPKNFRDVGFLDNRDFIENVHLVRRSEAFDNMCISDLKYYGELAVLQIVSHFSSSVLFNEKFTSIRNTSKPSVVREKLLFEVLEIFNETEMKYDAIKEQTGKLFDIAFSKDSTELKVSREDKIMASKFVLFYEHHFCRMVNESDNIVARLCVHRRPSILIENLKIYLHKIYKSWTDMNKILLDFDNDYSVYRSFAHYSISCIILVSQAFSVAEFIKVNDVVNMIRVFKRFLDIKIFSENETNEHVFNSQSFKDYTRAFSFLTIVTRIMLLAYGESSSTNLDVISKYIDENAPDLKGIIELVLDTNSCAYRFLLEPVQKSGFHLTVSQMLKNRKFQEPLMSNEDNKQMKHNSGKNLNPDLPSLKTGTSCLLNGIESPQLPFNGRSAPSPVRNNSLPEFAQLPSFRSLSVSDMINPDYAQPTNGQNNTQVQSNKPINAQQQIPTSVQVPFMNTNEINNNNNNNNNNKNNINNINNNNSNNFSATSFNLGTLDEFVNNGDLEDLYSILWSDVYPDS 391BA6C52770436C 391BA6C52770436C med15_canga Mediator of RNA polymerase II transcription subunit 15 GAL11 MED15 Mediator complex subunit 15 Transcription regulatory protein GAL11 CAGL0H06215g protein protein canga Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) Yeast Torulopsis glabrata MSSKETIPMHQRSQNVAELLTVLMDINKINGGDSTTAEKMKVHAKSFEAALFEKSSSKEEYQKTMKSKIDAMRSTRDKRKRESVGSASMMANLGQDGTNNNNNNNNNNNNNLNMAASFMGGDMFGRNQSPAQNSNANTNLNTNVGPGVNGPNGNDGTANPQMFMNQQAQARQQAAARQLKNRQMGGSSAQQQQLTQQQQQLLNQMRVAPIPKELLQRIPNLPPGVTTWEQVTALAQQNRLSAQDMSIAKDIYKIHQQYLIKAKLQQQQQRQQQQRQQGNPDVNNNMAGSNNNNNNNLPMAQQQMQQRQQQQQQSQQQQNRNPNQRHNVLSQINQMFTADEQRALLQEAMEACKNFQKTHFGGQMSDANKQAFIKKFINSKALKKLEAMRMAQGGNNNANLNKGQADMLQRQQANMQMNQQQQRAAQNQRRGPVMNDAVSQGYNNQMNSAADSTMNNSNQPMNIGNNGVNMIPNQSQQQQQTNRPKEQTPQQPQQRIQSNRSVPMLNPTPEDVEVVRRISAEAAKTQLRLTDLTNSLTPQERDEIKKRLQKNQQLFAQVSSYAPQVYLFTKSESFLKEVLQLRIFIKEILEKCSKGIYVVKLDTVDKLVIKYQKYWESMKIQLLRRQQLLQQQQQQQQQGMDPNRAQNSQQQQQQNQANMQQARNRKPTKNQTTPAIAASVAMNMNDKGASMSPALQKAGSAVPNFAQQMSPNMTPGTIPPTNVLSPHSQSHIPMVSPTMAKAASAAALKNDTASSSRRGSTKPRGKSTAPVTGKKTSNAPTPQVVPATVPSTTNLSAAGTPNIRNKSATPLTAGLSPKSTIRSNSNTALASAKTPSPMTVSIPQPGNSSVFKKEEEYLSKLQLRKEEIRFRQKQRLDILSSSPVDLFLTTVADCLGINDEEIELINKIPETTADNINNTGKKKLTKAAQKLRDKEILNVSIQVGEKDKLIMSSKAPDKVMDYSISAMSLAAVFKNLSSTGSLNNIALSGSNATTSKDIGNIYSHTGGVKRKFDEVEISPNSNGSPSASIMSESKKIKIDSPEDMFVTHSSEAAKGTNNSSLMDSGKEGSCKSMAGSATEVNDTSIWDWNFWTSIE 903F3DF1ADC85348 q6fut5_canga Mediator of RNA polymerase II transcription subunit 15 GAL11B CAGL0F00803g protein protein canga Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) Yeast Torulopsis glabrata MSLDVSVRERTRNMNQLMRILMDINHLNGGDSGVLEKLRLSARNFESAIYEKSSTKQEYMASMREKIEGMQQTLQQKKHTPATPSQQVPPPQQQQQQQGSQPRITLTPQQQQLLLSKMQLAVIPQQLLSKIPNLPAGVSTWKDVTELASKNMLDQRTMEIVRGVYKVHQQLLLKASFEQQRKRQPPQQQQPQQPQQQQQQQQQQQQQQQQQQQQQQSPQNVTNGNLFHILLRLFQDEFLSSKYQEQLSKLFKMEEIKHIIQQAIEVGKKYATQRYQLGHMLTNEERVVFFKKFLNHVILKKMEETKGSNKTDATMMNLTDNHTQMGTGQESTVPQQFNTDQVISNNQMPVNNFNMNMNNNQMPQQPFQQQMPQLTLQQQQNLFQQQLQQQQQQQQQQQQQQQQAQIQAQQQQQQQQQQQQQQQQQQQQQQQLLMQNLAATKLDIEEIRNISMKAAKLQLQLTDLTNTLTNEEKDAIRSRLKTNQKLFVQVSNFAPQVYMMTKSKNFLKEVFQLRIFVKEILEKCANGIFVVKLETVDKLIMKYQRYWDSMRVQLLRRQSQTKQQEIQGALQQMQRVEAQNNNNNNNYNNNNNNNSTNNNTNNNPQMPNLNNSNIITNFSTPFQVPIATPNNITNAVKKESRKPSVSASNASTPGTTSGKAKPKSRSNRQNSRSNSINEVSSDSTKQPQTTEAVSKEEAAKIHEANVRKSEILSRFKHRQKLFITSPADLFLSTLGDCLGLKCEEIETSYKIPKNMADFINGVKISKTEQRIRTQDTVVTSVVDNKLLMQSKTGGDKRTYGIDPAALSAVFKGVQGTTNMNTLQLFSSSSLSPVTEENA C578A30B903526C1 p36956-1 Sterol regulatory element-binding protein 1 SREBF1 BHLHD1 SREBP1 Class D basic helix-loop-helix protein 1 Sterol regulatory element-binding transcription factor 1 protein protein human Homo sapiens Human MDEPPFSEAALEQALGEPCDLDAALLTDIEDMLQLINNQDSDFPGLFDPPYAGSGAGGTDPASPDTSSPGSLSPPPATLSSSLEAFLSGPQAAPSPLSPPQPAPTPLKMYPSMPAFSPGPGIKEESVPLSILQTPTPQPLPGALLPQSFPAPAPPQFSSTPVLGYPSPPGGFSTGSPPGNTQQPLPGLPLASPPGVPPVSLHTQVQSVVPQQLLTVTAAPTAAPVTTTVTSQIQQVPVLLQPHFIKADSLLLTAMKTDGATVKAAGLSPLVSGTTVQTGPLPTLVSGGTILATVPLVVDAEKLPINRLAAGSKAPASAQSRGEKRTAHNAIEKRYRSSINDKIIELKDLVVGTEAKLNKSAVLRKAIDYIRFLQHSNQKLKQENLSLRTAVHKSKSLKDLVSACGSGGNTDVLMEGVKTEVEDTLTPPPSDAGSPFQSSPLSLGSRGSGSGGSGSDSEPDSPVFEDSKAKPEQRPSLHSRGMLDRSRLALCTLVFLCLSCNPLASLLGARGLPSPSDTTSVYHSPGRNVLGTESRDGPGWAQWLLPPVVWLLNGLLVLVSLVLLFVYGEPVTRPHSGPAVYFWRHRKQADLDLARGDFAQAAQQLWLALRALGRPLPTSHLDLACSLLWNLIRHLLQRLWVGRWLAGRAGGLQQDCALRVDASASARDAALVYHKLHQLHTMGKHTGGHLTATNLALSALNLAECAGDAVSVATLAEIYVAAALRVKTSLPRALHFLTRFFLSSARQACLAQSGSVPPAMQWLCHPVGHRFFVDGDWSVLSTPWESLYSLAGNPVDPLAQVTQLFREHLLERALNCVTQPNPSPGSADGDKEFSDALGYLQLLNSCSDAAGAPAYSFSISSSMATTTGVDPVAKWWASLTAVVIHWLRRDEEAAERLCPLVEHLPRVLQESERPLPRAALHSFKAARALLGCAKAESGPASLTICEKASGYLQDSLATTPASSSIDKAVQLFLCDLLLVVRTSLWRQQQPPAPAPAAQGTSSRPQASALELRGFQRDLSSLRRLAQSFRPAMRRVFLHEATARLMAGASPTRTHQLLDRSLRRRAGPGGKGGAVAELEPRPTRREHAEALLLASCYLPPGFLSAPGQRVGMLAEAARTLEKLGDRRLLHDCQQMLMRLGGGTTVTSS DIP protein P36956-1 original sequence version: 150 DIP protein P36956-1 original sequence version: 91 DIP protein P36956 original sequence version: 151 58F28870739FF259 crebbp-creb1-3 12 18 unspecified role unspecified role prey prey Region 270-325 Region 270-325 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain human Homo sapiens Human 14 unspecified role unspecified role prey prey human Homo sapiens Human 15 unspecified role unspecified role bait bait Region 590-671 Region 590-671 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain GST-tag GST-tag tag tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecolx Escherichia coli 19 unspecified role unspecified role prey prey Region 966-1068 Region 966-1068 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 22 unspecified role unspecified role prey prey spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm physical association physical association scgal11p-scpdr1p-1 4 16 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged c-term range C-terminal range c-term range c-term range C-terminal range c-term range Region 1-100 Region 1-100 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 19 unspecified role unspecified role prey prey Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association med15-scpdr1p-1 5 13 unspecified role unspecified role bait bait Region 9-77 Region 9-77 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 19 unspecified role unspecified role prey prey Region 966-1068 Region 966-1068 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 22 unspecified role unspecified role prey prey spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm physical association physical association cggal11bp-pdr1-1 6 21 unspecified role unspecified role bait bait Region 1-77 Region 1-77 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain GST-tag GST-tag tag tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecolx Escherichia coli 17 unspecified role unspecified role prey prey Region 1074-1104 Region 1074-1104 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain in vitro In vitro direct interaction direct interaction scgal11p-srebf1-1 10 22 unspecified role unspecified role prey prey spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm 16 unspecified role unspecified role bait bait Region 1-100 Region 1-100 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain GST-tag GST-tag tag tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecolx Escherichia coli direct interaction direct interaction scgal11p-srebf1-2 9 22 unspecified role unspecified role unspecified role unspecified role Region 17-42 Region 17-42 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain in vitro In vitro 16 unspecified role unspecified role unspecified role unspecified role Region 1-100 Region 1-100 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction pdr1-1 8 16 unspecified role unspecified role prey prey Region 1-100 Region 1-100 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain GST-tag GST-tag tag tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecolx Escherichia coli 17 unspecified role unspecified role prey prey Region 1074-1104 Region 1074-1104 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain in vitro In vitro direct interaction direct interaction scgal11p-scpdr1p-2 11 16 unspecified role unspecified role unspecified role unspecified role Region 1-100 Region 1-100 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 19 unspecified role unspecified role unspecified role unspecified role Region 1049-1060 Region 1049-1060 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain in vitro In vitro direct interaction direct interaction scgal11p-scpdr1p-3 7 16 unspecified role unspecified role bait bait GST-tag GST-tag tag tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range Region 1-100 Region 1-100 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain P19659:p.Val27Asp V27D mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain V D This feature has been corrected as a result of our quality control procedures. The original label was 'V27D'. Wed May 02 15:31:45 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'val27asp' Tue Jun 30 18:07:43 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Val27Asp' P19659:p.Lys63Gln K63Q mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain K Q This feature has been corrected as a result of our quality control procedures. The original label was 'K63Q'. Wed May 02 14:53:15 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'lys63gln' Tue Jun 30 16:41:24 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Lys63Gln' P19659:p.Ser69Asp S69D mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain S D This feature has been corrected as a result of our quality control procedures. The original label was 'S69D'. Wed May 02 15:44:07 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ser69asp' Tue Jun 30 16:52:47 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ser69Asp' P19659:p.Val76Asp V76D mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain V D This feature has been corrected as a result of our quality control procedures. The original label was 'V76D'. Wed May 02 19:25:07 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'val76asp' Tue Jun 30 17:26:52 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Val76Asp' P19659:p.Met77Glu M77E mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain M E This feature has been corrected as a result of our quality control procedures. The original label was 'M77E'. Wed May 02 16:29:58 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'met77glu' Tue Jun 30 16:44:46 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Met77Glu' P19659:p.Arg78Leu R78L mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain R L This feature has been corrected as a result of our quality control procedures. The original label was 'R78L'. Wed May 02 14:37:57 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'arg78leu' Tue Jun 30 16:57:40 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Arg78Leu' ecolx Escherichia coli 19 unspecified role unspecified role prey prey Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association scgal11p-scpdr1p-4 1 19 unspecified role unspecified role prey prey Region 966-1068 Region 966-1068 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 22 unspecified role unspecified role prey prey spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm 16 unspecified role unspecified role bait bait Region 1-100 Region 1-100 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain GST-tag GST-tag tag tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecolx Escherichia coli physical association physical association scgal11p-scpdr1p-5 2 16 unspecified role unspecified role bait bait Region 1-100 Region 1-100 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain GST-tag GST-tag tag tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecolx Escherichia coli 19 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association cggal11ap-pdr1-1 3 20 unspecified role unspecified role bait bait Region 1-79 Region 1-79 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain GST-tag GST-tag tag tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecolx Escherichia coli 17 unspecified role unspecified role prey prey Region 1074-1104 Region 1074-1104 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain in vitro In vitro direct interaction direct interaction